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Conserved domains on  [gi|985348059|gb|KXA30828|]
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N-acetylmuramic acid phosphotransfer permease [Klebsiella pneumoniae]

Protein Classification

PTS N-acetylmuramic acid transporter subunit IIBC( domain architecture ID 11484382)

PTS N-acetylmuramic acid transporter subunit IIBC is component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
murP PRK09586
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
 1-477 0e+00

PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed


:

Pssm-ID: 181971 [Multi-domain]  Cd Length: 476  Bit Score: 872.46  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   1 MAKITKEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMN 80
Cdd:PRK09586   1 MAKISSELLNTILTRVGGPGNIASCGNCMTRLRLTLHDSSLVDPAAIKTIEGVKGVILSDDQVQVVLGPGKAQRAAKAMN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  81 GLLEAAPAAAPTLADVAAEKKQALKGRQTSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLEnAHPNASLVA 160
Cdd:PRK09586  81 ELLGEAAAPVQDLAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIEQVMHVP-ADAQGTLPD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 161 LIGYMKVFSKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFVLGYNPEATSGFYAGISTFFGHGIDPRGNIIGVLIAAI 240
Cdd:PRK09586 160 ALNYMKVFSKGLFTFLSILIGYNAQQAFGGTGVNGAIIASLFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 241 LGAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGNPFGSAVLAGLFLLAVMFGVHQ 320
Cdd:PRK09586 240 AGARIERMVRRFMPDDLDMILTSLITLLITGALAFLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQ 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 321 GFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFVTA 400
Cdd:PRK09586 320 GFIPVYFALMDSQGFNSLFPILAMAGAGQVGAALALYWRAQKHSALRTQVKGAIIPGLLGVGEPLIYGVTLPRMKPFVTA 399

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 985348059 401 CLGGACGGFFVGLIAWLGLPVGLNTVFGPSGLVALPLMTSGSGIYAGMAVYAGGLAVSYLCGFVLTWLFGSKNVDLS 477
Cdd:PRK09586 400 CLGGAAGGFFIGLIAWLGLPVGLNSVFGPSGLVALPLMTSAQGILPGMAVYAGGLLVAYVCGFIFTTLFGCKNVDLD 476
 
Name Accession Description Interval E-value
murP PRK09586
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
 1-477 0e+00

PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed


Pssm-ID: 181971 [Multi-domain]  Cd Length: 476  Bit Score: 872.46  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   1 MAKITKEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMN 80
Cdd:PRK09586   1 MAKISSELLNTILTRVGGPGNIASCGNCMTRLRLTLHDSSLVDPAAIKTIEGVKGVILSDDQVQVVLGPGKAQRAAKAMN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  81 GLLEAAPAAAPTLADVAAEKKQALKGRQTSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLEnAHPNASLVA 160
Cdd:PRK09586  81 ELLGEAAAPVQDLAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIEQVMHVP-ADAQGTLPD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 161 LIGYMKVFSKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFVLGYNPEATSGFYAGISTFFGHGIDPRGNIIGVLIAAI 240
Cdd:PRK09586 160 ALNYMKVFSKGLFTFLSILIGYNAQQAFGGTGVNGAIIASLFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 241 LGAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGNPFGSAVLAGLFLLAVMFGVHQ 320
Cdd:PRK09586 240 AGARIERMVRRFMPDDLDMILTSLITLLITGALAFLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQ 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 321 GFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFVTA 400
Cdd:PRK09586 320 GFIPVYFALMDSQGFNSLFPILAMAGAGQVGAALALYWRAQKHSALRTQVKGAIIPGLLGVGEPLIYGVTLPRMKPFVTA 399

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 985348059 401 CLGGACGGFFVGLIAWLGLPVGLNTVFGPSGLVALPLMTSGSGIYAGMAVYAGGLAVSYLCGFVLTWLFGSKNVDLS 477
Cdd:PRK09586 400 CLGGAAGGFFIGLIAWLGLPVGLNSVFGPSGLVALPLMTSAQGILPGMAVYAGGLLVAYVCGFIFTTLFGCKNVDLD 476
PtsG1 COG1263
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ...
 105-475 8.09e-68

Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];


Pssm-ID: 440875 [Multi-domain]  Cd Length: 463  Bit Score: 224.05  E-value: 8.09e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 105 KGRQTSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLENAHPNASLVALigyMKVFSKGMFTFLSILIGYNA 184
Cdd:COG1263    1 AKKKKNPLFRFLQKIGGIFMPPIPVLPAAGLLLGLGALLTNPGLLGEGSFLSGTYQI---LNAAGDAVFYFLPLLFAIGA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 185 QKAFGGSGVNGAIIASLFVLGYNPEATsGFYAGISTFFG--HGIDPRGNIIGVLIAAILGAWVERQVRRVMPANLDMILT 262
Cdd:COG1263   78 AKGFGGNPALAAVIGYLLVHPTLLNAY-AVAGGYISFLGipTLIGYQGGVFPGILAGWLAAYLEKFLKKKLPDALGFFFV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 263 SAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGN--PFGSAVLAGLFLLAVMFGVHQGFVPVYFALVDAQGFNSLFP 340
Cdd:COG1263  157 PILTLLIMVPLALLVIGPIWPPIGNGIAAGLGWIYGLagAIGGFIYGFLYRLLVPTGLHHGLNPIFWFLLGGTGDDGLFP 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 341 ILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFL-GIGEPLIYGVTLPRMKPFVTACLGGACGGFFVGLIAWLGl 419
Cdd:COG1263  237 ILAAAMFGQPGAALAVYLKAKPNKKVKGLAISAALTAFLtGITEPAEFGFNLVAPKLFIAHAIGGGLGGAIAGLLGVKA- 315

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 985348059 420 pvglnTVFGPSGLVALPLMTSGSGiyAGMAVYAGGLAVSYLCGFVLTWLFGSKNVD 475
Cdd:COG1263  316 -----FSFGVGGLIDFPSILNPGA--TNLLLYLIGLVIAFVYYFVFTFLIGREDEE 364
PTS-II-ABC-beta TIGR01995
PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS ...
 6-472 1.06e-63

PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.


Pssm-ID: 273919 [Multi-domain]  Cd Length: 610  Bit Score: 217.22  E-value: 1.06e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059    6 KEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMNgllea 85
Cdd:TIGR01995   2 QDLAKAIIENVGGKENIESVTHCATRLRFTLKDDAKADTEKLKKISGVITVVKSGGQYQVVIGNDVNDVYQALMD----- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   86 apaaaPTLADVAAEKKQALKGRqtSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLEnahPNASLVALIGYM 165
Cdd:TIGR01995  77 -----VLGLDDQAEDDDSKGKK--SILNKLIDLISGVFTPLLPALAGAGLLKAVLTLLTMTGLIS---ADSQTYQILNAM 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  166 kvfSKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFVlgyNPEATSGFYAGIS-TFFGHGIDP---RGNIIGVLIAAIL 241
Cdd:TIGR01995 147 ---GDAVFYFLPILLAITAAKRFKVNPYLAAAIGAALL---HPTLVAMVGSGKPvTFFGIPVTLmsySSSVIPVILAVWL 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  242 GAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGNP--FGSAVLAGLFLLAVMFGVH 319
Cdd:TIGR01995 221 MSYVEKFLKKVIPGALKNFLTPLLVMLITVPLTLLIIGPLGNYAGEGISSGILFLYEVSpwLAGALLAALWPVLVMFGLH 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  320 QGFVPVYFALVDAQGFNSLF-PILAMAGAGQVGAALALFWRAKrDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFV 398
Cdd:TIGR01995 301 WAMIPIVINNIATQGFDPLIlPASLAANFAQGGAALAVMLRTK-NKKLKALAGSATISALFGITEPAIYGVNLPLKKPFY 379

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985348059  399 TACLGGACGGFFVGLIAwlglpVGLNTVFGPsGLVALPlMTSGSGIYAGMAVYAGGLAVSYLCGFVLTWLFGSK 472
Cdd:TIGR01995 380 AAMIGGAVGGAIIGIGS-----VKAFTAFAP-GLLGLP-MFINPSDGANFISALIAIVISFVVSFVLTYFIGFK 446
PTS_EIIC pfam02378
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ...
 122-404 2.08e-28

Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.


Pssm-ID: 367061  Cd Length: 315  Bit Score: 114.37  E-value: 2.08e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  122 IFTPLIPGFIAVGLLLGFATLAEQVFVLENAHPNAsLVALIGYMKVFSKGMFTFLSILIGYNAQKAF-GGSGVNGAIIAS 200
Cdd:pfam02378   3 GFMPPIPLLIAGGILLGLGNLPNDTTGLPAGGFTG-DSPLAEILKQAGSAAFGILPILFAIGIAYGLaGGDGVAGAAGLI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  201 LFVLGYNPEATSGF--------YAGISTFFGHGIDPRGNIIGVLIAAILGAWVERQVRRVMPANLDMILTSAVTLLIMGA 272
Cdd:pfam02378  82 GLLSFNLAAAISVAltaaglsgGGNILGIGLGATGVFGAIIPGLLAAYLYNRFEKNITIKLPDSLPFFVGKRFVPIITGF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  273 VTFTVIMPIGGWLFTGMS------WLFLHLNGNPFGSAVLAGLFLLAVMFGVHQGFVPVYFALV---------------D 331
Cdd:pfam02378 162 VTLLVIGPVLGLIWPAIQgglnalGLLLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFLPiggsnpianqqaygaG 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985348059  332 AQGFNSLFPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKP-FVTACLGG 404
Cdd:pfam02378 242 AAHILTGGFDVMFGGPGATLALYAAAFLFKKSKVKKLLGSAALTPFLFGITEPLEFGFPFVLNPPfFIPAILAG 315
PTS_IIB_glc cd00212
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ...
 6-83 8.34e-28

PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation


Pssm-ID: 238130 [Multi-domain]  Cd Length: 78  Bit Score: 105.69  E-value: 8.34e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 985348059   6 KEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMNGLL 83
Cdd:cd00212    1 EQLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLGGVKGVVKNGGQYQVIIGPGVADVYKEAIKLLG 78
 
Name Accession Description Interval E-value
murP PRK09586
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
 1-477 0e+00

PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed


Pssm-ID: 181971 [Multi-domain]  Cd Length: 476  Bit Score: 872.46  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   1 MAKITKEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMN 80
Cdd:PRK09586   1 MAKISSELLNTILTRVGGPGNIASCGNCMTRLRLTLHDSSLVDPAAIKTIEGVKGVILSDDQVQVVLGPGKAQRAAKAMN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  81 GLLEAAPAAAPTLADVAAEKKQALKGRQTSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLEnAHPNASLVA 160
Cdd:PRK09586  81 ELLGEAAAPVQDLAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIEQVMHVP-ADAQGTLPD 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 161 LIGYMKVFSKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFVLGYNPEATSGFYAGISTFFGHGIDPRGNIIGVLIAAI 240
Cdd:PRK09586 160 ALNYMKVFSKGLFTFLSILIGYNAQQAFGGTGVNGAIIASLFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 241 LGAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGNPFGSAVLAGLFLLAVMFGVHQ 320
Cdd:PRK09586 240 AGARIERMVRRFMPDDLDMILTSLITLLITGALAFLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQ 319

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 321 GFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFVTA 400
Cdd:PRK09586 320 GFIPVYFALMDSQGFNSLFPILAMAGAGQVGAALALYWRAQKHSALRTQVKGAIIPGLLGVGEPLIYGVTLPRMKPFVTA 399

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 985348059 401 CLGGACGGFFVGLIAWLGLPVGLNTVFGPSGLVALPLMTSGSGIYAGMAVYAGGLAVSYLCGFVLTWLFGSKNVDLS 477
Cdd:PRK09586 400 CLGGAAGGFFIGLIAWLGLPVGLNSVFGPSGLVALPLMTSAQGILPGMAVYAGGLLVAYVCGFIFTTLFGCKNVDLD 476
PtsG1 COG1263
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ...
 105-475 8.09e-68

Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];


Pssm-ID: 440875 [Multi-domain]  Cd Length: 463  Bit Score: 224.05  E-value: 8.09e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 105 KGRQTSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLENAHPNASLVALigyMKVFSKGMFTFLSILIGYNA 184
Cdd:COG1263    1 AKKKKNPLFRFLQKIGGIFMPPIPVLPAAGLLLGLGALLTNPGLLGEGSFLSGTYQI---LNAAGDAVFYFLPLLFAIGA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 185 QKAFGGSGVNGAIIASLFVLGYNPEATsGFYAGISTFFG--HGIDPRGNIIGVLIAAILGAWVERQVRRVMPANLDMILT 262
Cdd:COG1263   78 AKGFGGNPALAAVIGYLLVHPTLLNAY-AVAGGYISFLGipTLIGYQGGVFPGILAGWLAAYLEKFLKKKLPDALGFFFV 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 263 SAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGN--PFGSAVLAGLFLLAVMFGVHQGFVPVYFALVDAQGFNSLFP 340
Cdd:COG1263  157 PILTLLIMVPLALLVIGPIWPPIGNGIAAGLGWIYGLagAIGGFIYGFLYRLLVPTGLHHGLNPIFWFLLGGTGDDGLFP 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 341 ILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFL-GIGEPLIYGVTLPRMKPFVTACLGGACGGFFVGLIAWLGl 419
Cdd:COG1263  237 ILAAAMFGQPGAALAVYLKAKPNKKVKGLAISAALTAFLtGITEPAEFGFNLVAPKLFIAHAIGGGLGGAIAGLLGVKA- 315

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 985348059 420 pvglnTVFGPSGLVALPLMTSGSGiyAGMAVYAGGLAVSYLCGFVLTWLFGSKNVD 475
Cdd:COG1263  316 -----FSFGVGGLIDFPSILNPGA--TNLLLYLIGLVIAFVYYFVFTFLIGREDEE 364
PTS-II-ABC-beta TIGR01995
PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS ...
 6-472 1.06e-63

PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.


Pssm-ID: 273919 [Multi-domain]  Cd Length: 610  Bit Score: 217.22  E-value: 1.06e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059    6 KEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMNgllea 85
Cdd:TIGR01995   2 QDLAKAIIENVGGKENIESVTHCATRLRFTLKDDAKADTEKLKKISGVITVVKSGGQYQVVIGNDVNDVYQALMD----- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   86 apaaaPTLADVAAEKKQALKGRqtSAVQKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLEnahPNASLVALIGYM 165
Cdd:TIGR01995  77 -----VLGLDDQAEDDDSKGKK--SILNKLIDLISGVFTPLLPALAGAGLLKAVLTLLTMTGLIS---ADSQTYQILNAM 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  166 kvfSKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFVlgyNPEATSGFYAGIS-TFFGHGIDP---RGNIIGVLIAAIL 241
Cdd:TIGR01995 147 ---GDAVFYFLPILLAITAAKRFKVNPYLAAAIGAALL---HPTLVAMVGSGKPvTFFGIPVTLmsySSSVIPVILAVWL 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  242 GAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHLNGNP--FGSAVLAGLFLLAVMFGVH 319
Cdd:TIGR01995 221 MSYVEKFLKKVIPGALKNFLTPLLVMLITVPLTLLIIGPLGNYAGEGISSGILFLYEVSpwLAGALLAALWPVLVMFGLH 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  320 QGFVPVYFALVDAQGFNSLF-PILAMAGAGQVGAALALFWRAKrDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFV 398
Cdd:TIGR01995 301 WAMIPIVINNIATQGFDPLIlPASLAANFAQGGAALAVMLRTK-NKKLKALAGSATISALFGITEPAIYGVNLPLKKPFY 379

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985348059  399 TACLGGACGGFFVGLIAwlglpVGLNTVFGPsGLVALPlMTSGSGIYAGMAVYAGGLAVSYLCGFVLTWLFGSK 472
Cdd:TIGR01995 380 AAMIGGAVGGAIIGIGS-----VKAFTAFAP-GLLGLP-MFINPSDGANFISALIAIVISFVVSFVLTYFIGFK 446
PRK09824 PRK09824
PTS system beta-glucoside-specific transporter subunits IIABC; Provisional
 6-470 4.61e-52

PTS system beta-glucoside-specific transporter subunits IIABC; Provisional


Pssm-ID: 236627 [Multi-domain]  Cd Length: 627  Bit Score: 186.07  E-value: 4.61e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   6 KEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGpgkaQTAAEMMNGLLEA 85
Cdd:PRK09824   4 TELAREIVAGVGGADNIVSLMHCATRLRFKLKDNSKAQAEVLKKNPGVIMVVESGGQFQVVIG----NHVADVFLAVNSV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  86 APAAAPTLADVAAEKKQALKGRqtsavqkFLAKFATIFTPLIPGFIAVGLLLGFATLAeqvFVLENAHPNAslvaliGYM 165
Cdd:PRK09824  80 AGLGEKAQQAPENDKKGNLLNR-------FIDVISGIFTPLIGVMAATGILKGMLALA---LTFGWTTEQS------GTY 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 166 KVF---SKGMFTFLSILIGYNAQKAFGG----SGVNGA------IIASlFVLGYNPEATSGFYAGISTFFghgIDPRGNI 232
Cdd:PRK09824 144 KILfaaSDALFFFFPIILGYTAGKKFGGnpftAMVIGGalvhplMIAA-FEAGQKADALGLDFLGIPVTL---LNYSSSV 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 233 IGVLIAAILGAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGW----LFTGMSWLFlhlNGNP-FGSAVLA 307
Cdd:PRK09824 220 IPIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVIVPLTFLLIGPLATWlselLAAGYQWLY---QAVPaFAGAVMG 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 308 GLFLLAVMFGVHQGFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAkRDSLLRTQIKGAIIPGFLGIGEPLIY 387
Cdd:PRK09824 297 AFWQVFVIFGLHWGLVPLMINNLTVLGHDTMLPLLMPAVMAQVGAALGVFLCT-RDAQKKVVAGSAFLAGLFGITEPAVY 375

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 388 GVTLPRMKPFVTACLGGACGGFFVGLIAWLGLPVGLNTVFGPSGlvalplMTSGSGIYAgmAVYAG--GLAVSYLCGFVL 465
Cdd:PRK09824 376 GVNLPLKRPFIFGCISGALGAAIIGYAQTKVYSFGLPSIFTFMQ------TIPPTGIDF--TVWASviGTVIAIGCAFVG 447


                 ....*
gi 985348059 466 TWLFG 470
Cdd:PRK09824 448 TVMFG 452
PRK11007 PRK11007
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
 1-413 2.59e-37

PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional


Pssm-ID: 182896  Cd Length: 473  Bit Score: 142.52  E-value: 2.59e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   1 MAKITKEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGpgkaQTAAEMMN 80
Cdd:PRK11007   2 MSKINQQDIDRLIELVGGRENIATVSHCITRLRFVLNDPANADPKEIEQLPMVKGCFTNAGQFQVVIG----TEVGDYYK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  81 GLLEaapaaapTLADVAAEKKQA-LKGRQT-SAVQKFLAKFATIFTPLIPGFIAVGLLLGF------------ATLAEQV 146
Cdd:PRK11007  78 ALIA-------TTGQAEVDKEQAkKAARQNmKWHERLISHFAEIFFPLLPALISGGLILGFrnvigdipmsdgQTLAQMY 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 147 FVLENAHpnaSLVALIGymkvfsKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFVlgyNPEATSGFYAGIST------ 220
Cdd:PRK11007 151 PFWQTIY---DFLWLIG------EAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLV---SPQLMNAYLLGQQLpevwdf 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 221 --FFGHGIDPRGNIIGVLIAAILGAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWLFLHL-N 297
Cdd:PRK11007 219 glFSIEKVGYQAQVIPALLAGLALGFIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVKALmT 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 298 GN--PFGSAVLAGLFLLAVMFGVHQGFVPVYFALVDAQGFNSLFPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAiI 375
Cdd:PRK11007 299 GSfaPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQASAVVGIIIISRKHNEREISVPAA-I 377

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 985348059 376 PGFLGIGEPLIYGVTLPRMKPFVTACLGGACGGFFVGL 413
Cdd:PRK11007 378 SAYLGVTEPAMYGINLKYRFPMLCAMIGSALAGLICGL 415
PRK09796 PRK09796
PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional
 1-407 8.65e-29

PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional


Pssm-ID: 182081  Cd Length: 472  Bit Score: 118.36  E-value: 8.65e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059   1 MAKITKEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMN 80
Cdd:PRK09796   1 MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDALIDSPTLKTIPGVLGVVRSDNQCQVIIGNTVSQAFQEVVS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  81 GLLEAAPAaaptlADVAAEKKQALKGRQTsavqKFLAKFATIFTPLIPGFIAVGLLLGFATLAEQVFVLENAHPNASLVA 160
Cdd:PRK09796  81 LLPGDMQP-----AQPVGKPKLTLRRIGA----GILDALIGTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILN 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 161 LIGymkvfsKGMFTFLSILIGYNAQKAFGGSGVNGAIIASLFV----LGYNPEATSG---FYAGISTffgHGIDPRGNII 233
Cdd:PRK09796 152 VIG------DGAFFFLPLMVAASAAIKFKTNMSLAIAIAGVLVhpsfIELMAKAAQGehvEFALIPV---TAVKYTYTVI 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 234 GVLIAAILGAWVERQVRRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGWLFTGMSWL--FLHLNGNPFGSAVLAGLFL 311
Cdd:PRK09796 223 PALVMTWCLSYIERWVDRITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGSAISALvyTIHGYLGWLSVAIMGALWP 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059 312 LAVMFGVHQGFVPVYFALVDAQGFNSL-FPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFLGIGEPLIYGVT 390
Cdd:PRK09796 303 LLVMTGMHRVFTPTIIQTIAETGKEGMvMPSEIGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVA 382

                        410
                 ....*....|....*....
gi 985348059 391 LpRMKPFVTACL--GGACG 407
Cdd:PRK09796 383 I-RLKRPLIASLisGFICG 400
PTS_EIIC pfam02378
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ...
 122-404 2.08e-28

Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.


Pssm-ID: 367061  Cd Length: 315  Bit Score: 114.37  E-value: 2.08e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  122 IFTPLIPGFIAVGLLLGFATLAEQVFVLENAHPNAsLVALIGYMKVFSKGMFTFLSILIGYNAQKAF-GGSGVNGAIIAS 200
Cdd:pfam02378   3 GFMPPIPLLIAGGILLGLGNLPNDTTGLPAGGFTG-DSPLAEILKQAGSAAFGILPILFAIGIAYGLaGGDGVAGAAGLI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  201 LFVLGYNPEATSGF--------YAGISTFFGHGIDPRGNIIGVLIAAILGAWVERQVRRVMPANLDMILTSAVTLLIMGA 272
Cdd:pfam02378  82 GLLSFNLAAAISVAltaaglsgGGNILGIGLGATGVFGAIIPGLLAAYLYNRFEKNITIKLPDSLPFFVGKRFVPIITGF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  273 VTFTVIMPIGGWLFTGMS------WLFLHLNGNPFGSAVLAGLFLLAVMFGVHQGFVPVYFALV---------------D 331
Cdd:pfam02378 162 VTLLVIGPVLGLIWPAIQgglnalGLLLIIAGGILGGLIFGFLERLLWPFGLHGAFIAIFWFLPiggsnpianqqaygaG 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985348059  332 AQGFNSLFPILAMAGAGQVGAALALFWRAKRDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKP-FVTACLGG 404
Cdd:pfam02378 242 AAHILTGGFDVMFGGPGATLALYAAAFLFKKSKVKKLLGSAALTPFLFGITEPLEFGFPFVLNPPfFIPAILAG 315
PTS_IIB_glc cd00212
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ...
 6-83 8.34e-28

PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation


Pssm-ID: 238130 [Multi-domain]  Cd Length: 78  Bit Score: 105.69  E-value: 8.34e-28
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 985348059   6 KEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMNGLL 83
Cdd:cd00212    1 EQLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLGGVKGVVKNGGQYQVIIGPGVADVYKEAIKLLG 78
PtsG2 COG1264
Phosphotransferase system IIB components [Carbohydrate transport and metabolism];
6-80 1.61e-25

Phosphotransferase system IIB components [Carbohydrate transport and metabolism];


Pssm-ID: 440876 [Multi-domain]  Cd Length: 76  Bit Score: 99.42  E-value: 1.61e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 985348059   6 KEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIdGVMGVIVSDEQFQVVLGPGKAQTAAEMMN 80
Cdd:COG1264    1 KELAKDILEALGGKENIVSVDHCATRLRVTVKDPSKVDEAALKKL-GVKGVVKNGGQVQVIIGPGVDKVADEIEK 74
pts-Glc TIGR00852
PTS system, maltose and glucose-specific subfamily, IIC component; The PTS Glucose-Glucoside ...
 173-450 1.27e-24

PTS system, maltose and glucose-specific subfamily, IIC component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIC domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273299  Cd Length: 289  Bit Score: 103.17  E-value: 1.27e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  173 FTFLSILIGYNAQKAFGGSGVNGAIIASLFVLGYNPEATSGFYAGISTFFGHGIDP---RGNIIGVLIAAILGAWVERQV 249
Cdd:TIGR00852   5 FFFLPLLFAIGAAKGFGGNPYLGAALAGILVHPVLNNAMGVGAQAVGNFFGFEIAKvgyTGVVGPIIVGAIALALHERFL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  250 RRVMPANLDMILTSAVTLLIMGAVTFTVIMPIGGW-----LFTGMSWLFLHlnGNPFGSAVLAGLFLLAVMFGVHQGFVP 324
Cdd:TIGR00852  85 DKKLPDVLGFFLGPRFVVIIAGFVAILLIGPLGRVwppvgISALLHWLYSA--GGALGGAIFGFLYRLLVPTGLHHIFYA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985348059  325 VYFALV---DAQGFNSLFPILAMAGAGQVGAALALFWRAKrDSLLRTQIKGAIIPGFLGIGEPLIYGVTLPRMKPFVTAC 401
Cdd:TIGR00852 163 IFIQLIaggTVIGGGQVIPGDALANMAQGGAALAVFFTAG-DAKFKSIGLPAAFSAGLGITEPAMYGVALRERRPFVAGL 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 985348059  402 LGGACGGFFVGLIawlGLPVGLNTVFGPSGLVAL--PLMTSGSGIYAGMAV 450
Cdd:TIGR00852 242 IGSALLTAFLTGI---TEPLEFLFLFGAPGLYSIhaVLAGSIFTVAIGMGI 289
PRK14905 PRK14905
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ...
 7-84 1.14e-10

triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional


Pssm-ID: 184898 [Multi-domain]  Cd Length: 355  Bit Score: 63.13  E-value: 1.14e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 985348059   7 EMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPGKAQTAAEMMNGLLE 84
Cdd:PRK14905 276 EIAIQLIDHLGGKDNISALTHCASRIRVMLRNDGHIDKSAIEKIDCVKGLFSIANQYQIILGAGIVEKIHEEMKALLA 353
PTS_EIIB pfam00367
phosphotransferase system, EIIB;
10-41 1.75e-10

phosphotransferase system, EIIB;


Pssm-ID: 459785 [Multi-domain]  Cd Length: 32  Bit Score: 55.45  E-value: 1.75e-10
                          10        20        30
                  ....*....|....*....|....*....|..
gi 985348059   10 ARILAHVGGAANVAQAGNCMTRLRLTLRDESL 41
Cdd:pfam00367   1 KEILEALGGKENIKSVDHCATRLRLTVKDESK 32
PRK10110 PRK10110
PTS maltose transporter subunit IICB;
12-83 2.49e-07

PTS maltose transporter subunit IICB;


Pssm-ID: 182245 [Multi-domain]  Cd Length: 530  Bit Score: 53.20  E-value: 2.49e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 985348059  12 ILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQiDGVMGVIVSDEQ-FQVVLGPgKAQTAAEMMNGLL 83
Cdd:PRK10110 455 ILEALGGADNIVSLDNCITRLRLSVKDMSLVDVQALKD-NRAIGVVQLNQHnLQVVIGP-QVQSVKDEMAGLM 525
EIIB_glc TIGR00826
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) ...
 12-68 2.39e-06

PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIB domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273288 [Multi-domain]  Cd Length: 88  Bit Score: 45.43  E-value: 2.39e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 985348059   12 ILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQiDGVMGVIVSDEQFQVVLG 68
Cdd:TIGR00826  33 QIQALGGTGNVNKVDACITRLRVGVADVSKVDDAVLKK-LGAHGVNPLQRAVQVISG 88
EIIB_glc TIGR00826
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) ...
 30-70 1.07e-04

PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIB domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273288 [Multi-domain]  Cd Length: 88  Bit Score: 40.80  E-value: 1.07e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 985348059   30 TRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLGPG 70
Cdd:TIGR00826   1 TRLRLKTPGREKADEEAIAAGEGVKGVFTAAGQIQALGGTG 41
PRK09702 PRK09702
PTS sugar transporter subunit IIB;
10-68 2.35e-04

PTS sugar transporter subunit IIB;


Pssm-ID: 77355 [Multi-domain]  Cd Length: 161  Bit Score: 41.62  E-value: 2.35e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 985348059  10 ARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIDGVMGVIVSDEQFQVVLG 68
Cdd:PRK09702  74 AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVIIG 132
PRK11089 PRK11089
PTS system glucose-specific transporter subunits IIBC; Provisional
 2-69 9.99e-04

PTS system glucose-specific transporter subunits IIBC; Provisional


Pssm-ID: 182955 [Multi-domain]  Cd Length: 477  Bit Score: 41.62  E-value: 9.99e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 985348059   2 AKITKEMIARILAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIdGVMGVIVSDEQFQVVLGP 69
Cdd:PRK11089 395 ATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKL-GAAGVVVAGSGVQAIFGT 461
PRK10255 PRK10255
PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional
 13-83 6.82e-03

PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional


Pssm-ID: 182338 [Multi-domain]  Cd Length: 648  Bit Score: 39.08  E-value: 6.82e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 985348059  13 LAHVGGAANVAQAGNCMTRLRLTLRDESLADSAAIRQIdGVMGVIVSDEQ-FQVVLGpGKAQTAAEMMNGLL 83
Cdd:PRK10255 397 IAAVGGTDNLKAIDACITRLRLTVADSARVNDAMCKRL-GASGVVKLNKQtIQVIVG-AKAESIGDAMKKVV 466
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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