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Conserved domains on  [gi|985331389|gb|KXA14947|]
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fructose-1,6-bisphosphate aldolase, class II [Clostridium perfringens]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10097223)

class II fructose-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

CATH:  3.20.20.70
EC:  4.1.2.13
Gene Ontology:  GO:0004332|GO:0046872|GO:0006096
PubMed:  12206759
SCOP:  4003234

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 6-286 2.69e-139

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


:

Pssm-ID: 238477  Cd Length: 276  Bit Score: 393.82  E-value: 2.69e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   6 AKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEELkiTVPVALHLD 85
Cdd:cd00947    1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYA-GLELLVAMVKAAAERA--SVPVALHLD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  86 HG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA-GEIADPAECKQIA 163
Cdd:cd00947   78 HGsSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDeGLLTDPEEAEEFV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 164 EL-GVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFAEA 242
Cdd:cd00947  158 EEtGVDALAVAIGTSHGAYKGGEPKLDFDRLKEIAERV-NVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAA 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 985331389 243 TRKYIEAGKdlegKGFDPRKLLNPGFEAIKATVKEKMELFGSVN 286
Cdd:cd00947  237 LREYLAENP----KEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
 
Name Accession Description Interval E-value
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 6-286 2.69e-139

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 393.82  E-value: 2.69e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   6 AKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEELkiTVPVALHLD 85
Cdd:cd00947    1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYA-GLELLVAMVKAAAERA--SVPVALHLD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  86 HG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA-GEIADPAECKQIA 163
Cdd:cd00947   78 HGsSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDeGLLTDPEEAEEFV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 164 EL-GVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFAEA 242
Cdd:cd00947  158 EEtGVDALAVAIGTSHGAYKGGEPKLDFDRLKEIAERV-NVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAA 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 985331389 243 TRKYIEAGKdlegKGFDPRKLLNPGFEAIKATVKEKMELFGSVN 286
Cdd:cd00947  237 LREYLAENP----KEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 3-288 3.32e-139

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 393.65  E-value: 3.32e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389    3 LVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKItVPVAL 82
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSI-VPVAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   83 HLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA-GEIADPAECK 160
Cdd:TIGR01859  80 HLDHGsSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEKeAELADPDEAE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  161 QIA-ELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSF 239
Cdd:TIGR01859 160 QFVkETGVDYLAAAIGTSHGKYKGE-PGLDFERLKEIKELT-NIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAF 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 985331389  240 AEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:TIGR01859 238 TAAIRKVLTEKKDE----YDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 2-288 1.84e-133

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 379.05  E-value: 1.84e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   2 ALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEELkiTVPVA 81
Cdd:COG0191    1 MLVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYA-GLEYLAAMVRAAAEEA--SVPVA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  82 LHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVG---AGEIADPA 157
Cdd:COG0191   78 LHLDHGaSFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVddaEALYTDPE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 158 ECKQ-IAELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQ 236
Cdd:COG0191  158 EAAEfVEETGVDALAVAIGTVHGVYKGE-PKLDFDRLKEIREAV-PVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLR 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 985331389 237 LSFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:COG0191  236 LAFTAAVREYLAENPDK----YDPRKYLKPAREAMKEVVKEKIRLFGSAGKA 283
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
4-287 7.02e-130

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 369.82  E-value: 7.02e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389    4 VNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAA-KYMCGFKTIVGMVNGMLEELKitVPVAL 82
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAaKYAGGAEALAALVRAAAEAAG--VPVAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   83 HLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEI-ADPAECK 160
Cdd:pfam01116  79 HLDHGaSFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLyTDPEEAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  161 QIAE-LGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSF 239
Cdd:pfam01116 159 EFVEaTGVDALAVAIGNVHGVYKPG-PKLDFDRLKEIQEAV-PVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAF 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 985331389  240 AEATRKYieagkdleGKGFDPRKLLNPGFEAIKATVKEKMELFGSVNR 287
Cdd:pfam01116 237 TAAVREY--------PPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 1-288 1.58e-122

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 351.88  E-value: 1.58e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKITVPV 80
Cdd:PRK07315   1 MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKNLIENLVESMGITVPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHGSYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEIADPAECK 160
Cdd:PRK07315  81 AIHLDHGHYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 161 QIAELGVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATGDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFA 240
Cdd:PRK07315 161 AMVETGIDFLAAGIGNIHGPYPENWEGLDLDHLEKLTEAVPGFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFA 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 985331389 241 EATRKYIEAGKDLEG-----KGFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK07315 241 NATRKFARDYEANEAeydkkKLFDPRKFLAPGVKAIQASVEERIDVFGSANKA 293
 
Name Accession Description Interval E-value
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 6-286 2.69e-139

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 393.82  E-value: 2.69e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   6 AKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEELkiTVPVALHLD 85
Cdd:cd00947    1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYA-GLELLVAMVKAAAERA--SVPVALHLD 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  86 HG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA-GEIADPAECKQIA 163
Cdd:cd00947   78 HGsSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDeGLLTDPEEAEEFV 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 164 EL-GVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFAEA 242
Cdd:cd00947  158 EEtGVDALAVAIGTSHGAYKGGEPKLDFDRLKEIAERV-NVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAA 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 985331389 243 TRKYIEAGKdlegKGFDPRKLLNPGFEAIKATVKEKMELFGSVN 286
Cdd:cd00947  237 LREYLAENP----KEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 3-288 3.32e-139

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 393.65  E-value: 3.32e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389    3 LVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKItVPVAL 82
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSI-VPVAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   83 HLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA-GEIADPAECK 160
Cdd:TIGR01859  80 HLDHGsSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEKeAELADPDEAE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  161 QIA-ELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSF 239
Cdd:TIGR01859 160 QFVkETGVDYLAAAIGTSHGKYKGE-PGLDFERLKEIKELT-NIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAF 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 985331389  240 AEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:TIGR01859 238 TAAIRKVLTEKKDE----YDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 2-288 1.84e-133

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 379.05  E-value: 1.84e-133
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   2 ALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEELkiTVPVA 81
Cdd:COG0191    1 MLVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYA-GLEYLAAMVRAAAEEA--SVPVA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  82 LHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVG---AGEIADPA 157
Cdd:COG0191   78 LHLDHGaSFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVddaEALYTDPE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 158 ECKQ-IAELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQ 236
Cdd:COG0191  158 EAAEfVEETGVDALAVAIGTVHGVYKGE-PKLDFDRLKEIREAV-PVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLR 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 985331389 237 LSFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:COG0191  236 LAFTAAVREYLAENPDK----YDPRKYLKPAREAMKEVVKEKIRLFGSAGKA 283
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
4-287 7.02e-130

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 369.82  E-value: 7.02e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389    4 VNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAA-KYMCGFKTIVGMVNGMLEELKitVPVAL 82
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAaKYAGGAEALAALVRAAAEAAG--VPVAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   83 HLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEI-ADPAECK 160
Cdd:pfam01116  79 HLDHGaSFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLyTDPEEAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  161 QIAE-LGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSF 239
Cdd:pfam01116 159 EFVEaTGVDALAVAIGNVHGVYKPG-PKLDFDRLKEIQEAV-PVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAF 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 985331389  240 AEATRKYieagkdleGKGFDPRKLLNPGFEAIKATVKEKMELFGSVNR 287
Cdd:pfam01116 237 TAAVREY--------PPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 1-288 6.42e-128

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 365.49  E-value: 6.42e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389    1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKITVPV 80
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGLGAISAMVKAMSEAYPYGVPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA---GEIADP 156
Cdd:TIGR00167  81 ALHLDHGaSEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGVSVAdesALYTDP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  157 AECKQIAEL-GVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:TIGR00167 161 EEAKEFVKLtGVDSLAAAIGNVHGVYKGEPKGLDFERLEEIQKYV-NLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTEL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 985331389  236 QLSFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:TIGR00167 240 QIAFAAAVRNYYAENKDY----YDPRVWLRPGEKAMKEVVLEKIKLFGSANKA 288
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 1-288 1.58e-122

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 351.88  E-value: 1.58e-122
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKITVPV 80
Cdd:PRK07315   1 MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKNLIENLVESMGITVPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHGSYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEIADPAECK 160
Cdd:PRK07315  81 AIHLDHGHYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 161 QIAELGVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATGDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFA 240
Cdd:PRK07315 161 AMVETGIDFLAAGIGNIHGPYPENWEGLDLDHLEKLTEAVPGFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFA 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 985331389 241 EATRKYIEAGKDLEG-----KGFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK07315 241 NATRKFARDYEANEAeydkkKLFDPRKFLAPGVKAIQASVEERIDVFGSANKA 293
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 1-288 2.85e-116

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 335.80  E-value: 2.85e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKITVPV 80
Cdd:PRK08610   1 MPLVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTVVKMVEGLMHDLNITIPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEI-ADPAE 158
Cdd:PRK08610  81 AIHLDHGsSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIyADPKE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 159 CKQIAE-LGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATGdMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQL 237
Cdd:PRK08610 161 CQELVEkTGIDALAPALGSVHGPYKGE-PKLGFKEMEEIGLSTG-LPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 985331389 238 SFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK08610 239 ASAKAVRDVLNNDKEV----YDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 1-288 4.33e-113

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 327.78  E-value: 4.33e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKITVPV 80
Cdd:PRK07709   1 MPLVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEI-ADPAE 158
Cdd:PRK07709  81 AIHLDHGsSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGVIyADPAE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 159 CKQIAE-LGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATGdMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQL 237
Cdd:PRK07709 161 CKHLVEaTGIDCLAPALGSVHGPYKGE-PNLGFAEMEQVRDFTG-VPLVLHGGTGIPTADIEKAISLGTSKINVNTENQI 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 985331389 238 SFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK07709 239 EFTKAVREVLNKDQEV----YDPRKFIGPGRDAIKATVIGKIREFGSNGKA 285
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
1-288 4.16e-91

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 271.60  E-value: 4.16e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmCGFKTIVGMVNGMLEelKITVPV 80
Cdd:PRK12857   1 MMLVTVAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKY-AGIEYISAMVRTAAE--KASVPV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGV-VGAGE--IADP 156
Cdd:PRK12857  78 ALHLDHGtDFEQVMKCIRNGFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDItVDEREaaMTDP 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 157 AECKQIA-ELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:PRK12857 158 EEARRFVeETGVDALAIAIGTAHGPYKGE-PKLDFDRLAKIKELV-NIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNI 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 985331389 236 QLSFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK12857 236 REAFVARLREVLEKNPDE----IDPRKILGPAREAAKEVIREKIRLFGSAGKA 284
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 1-288 8.57e-82

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 248.12  E-value: 8.57e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEelKITVPV 80
Cdd:PRK09195   1 MYLVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYA-GTEYLLAIVSAAAK--QYHHPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEIA---DP 156
Cdd:PRK09195  78 ALHLDHHeKFDDIAQKVRSGVRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDLQVDEADAlytDP 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 157 AECKQIAE-LGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:PRK09195 158 AQAREFVEaTGIDSLAVAIGTAHGMYKGE-PKLDFDRLENIRQWV-NIPLVLHGASGLPTKDIQQTIKLGICKVNVATEL 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 985331389 236 QLSFAEATRKYIEAGKDLEgkgfDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK09195 236 KIAFSQALKNYLTEHPEAN----DPRHYLQPAKSAMKDVVSKVIADCGCEGKA 284
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
1-288 8.82e-79

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 240.37  E-value: 8.82e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmCGFKTIVGMVNGMLEELKItvPV 80
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSY-AGTDYIVAIAEVAARKYNI--PL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEIA---DP 156
Cdd:PRK12737  78 ALHLDHHeDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAmytNP 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 157 AECKQ-IAELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:PRK12737 158 DAAAEfVERTGIDSLAVAIGTAHGLYKGE-PKLDFERLAEIREKV-SIPLVLHGASGVPDEDVKKAISLGICKVNVATEL 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 985331389 236 QLSFAEATRKYIEAGKDLEgkgfDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK12737 236 KIAFSDAVKKYFYENPKAN----DPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
3-287 1.21e-63

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 202.51  E-value: 1.21e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   3 LVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMLEELKiTVPVAL 82
Cdd:PRK05835   2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYM-GIDMAVGMVKIMCERYP-HIPVAL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  83 HLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVV---GAGEIADPAE 158
Cdd:PRK05835  80 HLDHGtTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISvdeKDAVLVNPKE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 159 CKQ-IAELGVTMLAAGIGNIHGKYpaNWAG---LNFEALANIKAATgDMPLVLHGGTGIPSDM----------------- 217
Cdd:PRK05835 160 AEQfVKESQVDYLAPAIGTSHGAF--KFKGepkLDFERLQEVKRLT-NIPLVLHGASAIPDDVrksyldaggdlkgskgv 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 985331389 218 ----IAEAISLGVSKINVNTECQLSFAEATRKYieAGKDleGKGFDPRKLLNPGFEAIKATVKEKMELFGSVNR 287
Cdd:PRK05835 237 pfefLQESVKGGINKVNTDTDLRIAFIAEVRKV--ANED--KSQFDLRKFFSPAQLALKNVVKERMKLLGSANK 306
PRK06806 PRK06806
class II aldolase;
1-288 2.40e-63

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 200.75  E-value: 2.40e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmcgfkTIVGMVNGMLEEL--KITV 78
Cdd:PRK06806   1 MPLVQMKELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAEVRLNH-----SPLHLIGPLMVAAakQAKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  79 PVALHLDHGSYQGAI-DAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAG-EIADP 156
Cdd:PRK06806  76 PVAVHFDHGMTFEKIkEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEmLLTST 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 157 AECKQ-IAELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:PRK06806 156 TEAKRfAEETDVDALAVAIGNAHGMYNGD-PNLRFDRLQEINDVV-HIPLVLHGGSGISPEDFKKCIQHGIRKINVATAT 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 985331389 236 QLSFAEATRKYIEAGKDlegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK06806 234 FNSVITAVNNLVLNTPY-----SDYFTYHQDVIKAAYENVKKHMQIFGSENKA 281
PRK08185 PRK08185
hypothetical protein; Provisional
 7-288 3.37e-62

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 198.03  E-value: 3.37e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   7 KEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmcgfktiVG--MVNGMLEELKIT-VPVALH 83
Cdd:PRK08185   2 KELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDF-------LGdnFFAYVRERAKRSpVPFVIH 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  84 LDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVV-GAGEI--ADPAEC 159
Cdd:PRK08185  75 LDHGaTIEDVMRAIRCGFTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTIGNTGTSIEgGVSEIiyTDPEQA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 160 KQ-IAELGVTMLAAGIGNIHGKYPANWA-GLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQL 237
Cdd:PRK08185 155 EDfVSRTGVDTLAVAIGTAHGIYPKDKKpELQMDLLKEINERV-DIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKY 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 985331389 238 SFAEATRKYIEAGKDLegkgFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK08185 234 AFFKKVREILSDNPSL----YEPNQIYPSAIEAAKEVVRHKMDLFNSTGKA 280
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
1-288 6.32e-62

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 198.41  E-value: 6.32e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGfkTIVG-MVNG---MLEELKI 76
Cdd:PRK07084   7 LGLVNTREMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANA--TLLRyMAQGaveYAKELGC 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  77 TVPVALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGA-GEIA 154
Cdd:PRK07084  85 PIPIVLHLDHGdSFELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEhHTYT 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 155 DPAECKQ-IAELGVTMLAAGIGNIHGKY---PANW-AGLNFEALANIKAATGDMPLVLHGGT------------------ 211
Cdd:PRK07084 165 QPEEVEDfVKKTGVDSLAISIGTSHGAYkfkPGQCpPPLRFDILEEIEKRIPGFPIVLHGSSsvpqeyvktineyggklk 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 212 ---GIPSDMIAEAISLGVSKINVNTECQLSFAEATRKYIeagkDLEGKGFDPRKLLNPGFEAIKATVKEK-MELFGSVNR 287
Cdd:PRK07084 245 daiGIPEEQLRKAAKSAVCKINIDSDGRLAMTAAIRKVF----DEKPEEFDPRKYLGPARDELKKLYKHKiINVLGSNGK 320


                 .
gi 985331389 288 A 288
Cdd:PRK07084 321 A 321
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
1-287 9.52e-61

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 194.48  E-value: 9.52e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNGMleELKITVPV 80
Cdd:PRK12738   1 MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHI-ALEEIYALCSAY--STTYNMPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHGSYQGAID-AMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEIA---DP 156
Cdd:PRK12738  78 ALHLDHHESLDDIRrKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAfltDP 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 157 AECKQIAEL-GVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:PRK12738 158 QEAKRFVELtGVDSLAVAIGTAHGLYSKT-PKIDFQRLAEIREVV-DVPLVLHGASDVPDEFVRRTIELGVTKVNVATEL 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 985331389 236 QLSFAEATRKYIEAGKDlegkGFDPRKLLNPGFEAIKATVKEKMELFGSVNR 287
Cdd:PRK12738 236 KIAFAGAVKAWFAENPQ----GNDPRYYMRVGMDAMKEVVRNKINVCGSANR 283
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
1-288 4.91e-59

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 189.96  E-value: 4.91e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMcGFKTIVGMVNgmLEELKITVPV 80
Cdd:PRK06801   1 MALISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYI-SLESLVEAVK--FEAARHDIPV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVV-GAGEIA---D 155
Cdd:PRK06801  78 VLNLDHGlHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALyGEADSAkftD 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 156 PAECKQ-IAELGVTMLAAGIGNIHGKYPANwAGLNFEALANIKAATGdMPLVLHGGTGIPSDMIAEAISLGVSKINVNT- 233
Cdd:PRK06801 158 PQLARDfVDRTGIDALAVAIGNAHGKYKGE-PKLDFARLAAIHQQTG-LPLVLHGGSGISDADFRRAIELGIHKINFYTg 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 985331389 234 --ECQLSFAEATRKYIEAGKDlegkgfDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PRK06801 236 msQAALAAVEQRMTHRHAIYD------EFAELLLGIEEAISDTVAQQMRIFGSAGQA 286
PLN02858 PLN02858
fructose-bisphosphate aldolase
 5-288 1.35e-57

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 198.92  E-value: 1.35e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389    5 NAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmcGFKTIVGMVngMLEELKITVPVALHL 84
Cdd:PLN02858 1101 STKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALKQ--GGIPLVSCC--IAAAEQASVPITVHF 1176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   85 DHGSYQGA-IDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDGVVGAGEIADPAECKQ-- 161
Cdd:PLN02858 1177 DHGTSKHElLEALELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGTEDGLTVEEYEAKLTDVDQak 1256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  162 --IAELGVTMLAAGIGNIHGKYPANWAGLNFEALANIKAATGD--MPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQL 237
Cdd:PLN02858 1257 efIDETGIDALAVCIGNVHGKYPASGPNLRLDLLKELRALSSKkgVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRT 1336

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 985331389  238 SFAEATRKyieagkdleGKGFDPRKLLNPGFEAIKATVKEKMELFGSVNRA 288
Cdd:PLN02858 1337 AYMEALSS---------PKKTDLIDVMSAAKEAMKAVVAEKLRLFGSAGKA 1378
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
1-288 5.06e-53

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 176.30  E-value: 5.06e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmCGFKTIVGMVNGMLEELKiTVPV 80
Cdd:PRK09196   1 MALISLRQLLDHAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKY-AGEPFLRHLILAAVEEYP-HIPV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHGSY----QGAIdamDAGFSSVMFDGS-------HYSIEENIVKTKEIINLAAAKNVSVEAEVGSIG-------G 142
Cdd:PRK09196  79 VMHQDHGNSpatcQRAI---QLGFTSVMMDGSlkadgktPASYEYNVDVTRKVVEMAHACGVSVEGELGCLGsletgmgG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 143 EEDGVVGAGE------IADPAECKQ-IAELGVTMLAAGIGNIHGKY----PANWAGLNFEALANIKAATGDMPLVLHGGT 211
Cdd:PRK09196 156 EEDGHGAEGKlshdqlLTDPEEAADfVKKTQVDALAIAIGTSHGAYkftrKPTGDVLAIDRIKEIHARLPNTHLVMHGSS 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 212 GIPSDM---------------------IAEAISLGVSKINVNTECQLSFAEATRKYIEAGKdlegKGFDPRKLLNPGFEA 270
Cdd:PRK09196 236 SVPQELldiineyggdmpetygvpveeIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAENP----SEFDPRKYLKPAMEA 311

                        330
                 ....*....|....*...
gi 985331389 271 IKATVKEKMELFGSVNRA 288
Cdd:PRK09196 312 MKKICKARYEAFGTAGQA 329
gatY PRK07998
class II aldolase;
1-279 3.70e-52

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 172.25  E-value: 3.70e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKyMCGFKTIVGMVNGMLEelKITVPV 80
Cdd:PRK07998   1 MPLVNGRILLDRIQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQ-LSGYDYIYEIVKRHAD--KMDVPV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHG-SYQGAIDAMDAGFSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIGGEEDG-VVGAGEIADPAE 158
Cdd:PRK07998  78 SLHLDHGkTFEDVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDDhVSEADCKTEPEK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 159 CKQIAE-LGVTMLAAGIGNIHG--KYPanwaGLNFEALANIKAATgDMPLVLHGGTGIPSDMIAEAISLGVSKINVNTEC 235
Cdd:PRK07998 158 VKDFVErTGCDMLAVSIGNVHGleDIP----RIDIPLLKRIAEVS-PVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDL 232

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 985331389 236 QlsfaeatRKYIEA-GKDLEGKG--FDPRKLLNPGFEAIKATVKEKM 279
Cdd:PRK07998 233 R-------KAFITTvGKAYVNNHneANLARVMAKAKQAVEEDVYSKI 272
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
1-288 4.88e-50

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 168.42  E-value: 4.88e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   1 MALVNAKEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYmCGFKTIVGMVNGMLEELKiTVPV 80
Cdd:PRK13399   1 MALITLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKY-AGDAMLRHMVLAAAEMYP-DIPI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  81 ALHLDHGSYQGA-IDAMDAGFSSVMFDGS-------HYSIEENIVKTKEIINLAAAKNVSVEAEVGSIG-------GEED 145
Cdd:PRK13399  79 CLHQDHGNSPATcQSAIRSGFTSVMMDGSlladgktPASYDYNVDVTRRVTEMAHAVGVSVEGELGCLGsletgeaGEED 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 146 GVVGAGEIA------DPAECKQ-IAELGVTMLAAGIGNIHGKY----PANWAGLNFEALANIKAATGDMPLVLHGGT--- 211
Cdd:PRK13399 159 GVGAEGKLShdqmltDPDQAVDfVQRTGVDALAIAIGTSHGAYkftrKPDGDILAIDRIEEIHARLPNTHLVMHGSSsvp 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 212 ------------------GIPSDMIAEAISLGVSKINVNTECQLSFAEATRKYIEAGKDlegkGFDPRKLLNPGFEAIKA 273
Cdd:PRK13399 239 qelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRLAMTGAIRKVLAEHPS----EFDPRKALKPAMKAMTA 314

                        330
                 ....*....|....*
gi 985331389 274 TVKEKMELFGSVNRA 288
Cdd:PRK13399 315 LCKQRFEAFGTAGQA 329
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 7-286 8.14e-48

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 162.67  E-value: 8.14e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   7 KEMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCGFKTIVGMVNGMLEELKIT--------- 77
Cdd:cd00453    2 QKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISgahhvhqma 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  78 ----VPVALHLDHGSYQGAID---AMDAG-----------FSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGS 139
Cdd:cd00453   82 ehygVPVILHTDHCAKKLLPWidgLLDAGekhfaatgkplFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGC 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 140 IGGEEDGVVGAGEIA-----DPAECKQIAEL-----GVTMLAAGIGNIHGKYPANWAGLNFEALANIK--------AATG 201
Cdd:cd00453  162 TGGEEDGVDNSHMDAsalytQPEDVDYAYTElskisPRFTIAASFGNVHGVYKKGNVVLTPTILRDSQeyvskkhnLPHN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 202 DMPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFAEATRKYIEA-------------GKDLEG-KGFDPRKLLNPG 267
Cdd:cd00453  242 SLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKAneaylqgqlgnpkGEDQPNkKYYDPRVWLRAG 321

                        330
                 ....*....|....*....
gi 985331389 268 FEAIKATVKEKMELFGSVN 286
Cdd:cd00453  322 QTSMIARLEKAFQELNAID 340
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 8-287 9.08e-42

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 146.86  E-value: 9.08e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   8 EMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCG--------FKTIVGMVNG------MLEE 73
Cdd:PRK09197  11 EMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGkgvkddgqGAAVLGAIAGakhvheVAEH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  74 LKitVPVALHLDHGSYQ------GAIDA----MDAG----FSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGS 139
Cdd:PRK09197  91 YG--VPVILHTDHCAKKllpwidGLLDAgekhFAAGgkplFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTLEIELGV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 140 IGGEEDGVVGAGEIAD-----PAE-CKQIAELGVT----MLAAGIGNIHGKY-PANwAGLNFEALANI------KAATGD 202
Cdd:PRK09197 169 TGGEEDGVDNSHEDNSklytqPEDvLYAYEALGKIsgrfTIAASFGNVHGVYkPGN-VKLRPEILKDSqeyvskKFGLPA 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 203 MP--LVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFAEATRKYIEAGKD-LEG-------------KGFDPRKLLNP 266
Cdd:PRK09197 248 KPfdFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDyLQGqvgnpegedkpnkKYYDPRVWLRA 327

                        330       340
                 ....*....|....*....|.
gi 985331389 267 GFEAIKATVKEKMELFGSVNR 287
Cdd:PRK09197 328 AEASMAARLEEAFEDLNSIGV 348
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 8-287 1.95e-38

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 138.27  E-value: 1.95e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389   8 EMLNKAREGKYAVGQFNINNLEWTKAILLTAQENNSPVILGVSEGAAKYMCG--------FKTIVGMVNGMLEELKIT-- 77
Cdd:cd00946    6 KLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGkglknekqKASIAGAIAAAHHVRSMAeh 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389  78 --VPVALHLDHGS------YQGAIDAMDAG--------FSSVMFDGSHYSIEENIVKTKEIINLAAAKNVSVEAEVGSIG 141
Cdd:cd00946   86 ygVPVVLHTDHCAkkllpwFDGLLEADEEYfkqhgeplFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEMEIGITG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 142 GEEDGVVGAGEIAD-----PAEC-KQIAELGVT----MLAAGIGNIHGKYPANWAGLNFEALAN----IKAATGD----- 202
Cdd:cd00946  166 GEEDGVDNSGVDNAelytqPEDVwYVYEALSKIspnfSIAAAFGNVHGVYKPGNVKLQPEILGEhqdyVREKLGLaddkp 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 985331389 203 MPLVLHGGTGIPSDMIAEAISLGVSKINVNTECQLSFAEATRKYIEAGKD--------LEG------KGFDPRKLLNPGF 268
Cdd:cd00946  246 LYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDylqgqignPEGpdkpnkKYYDPRVWLREGE 325

                        330
                 ....*....|....*....
gi 985331389 269 EAIKATVKEKMELFGSVNR 287
Cdd:cd00946  326 KSMVARVKKAFEDLNSVNK 344
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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