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Conserved domains on  [gi|930084891|gb|KPH23225|]
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hypothetical protein AOT41_00630 [Limosilactobacillus fermentum]

Protein Classification

Asp23/Gls24 family envelope stress response protein( domain architecture ID 10003467)

Asp23/Gls24 family envelope stress response protein similar to Staphylococcus aureus alkaline shock protein 23 (Asp23) and Streptococcus pyogenes stress response regulator gls24 homolog

PubMed:  7864904

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YloU COG1302
Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family [Function ...
 10-120 1.81e-29

Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family [Function unknown];


:

Pssm-ID: 440913  Cd Length: 118  Bit Score: 102.55  E-value: 1.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 930084891  10 GMIDIANDVICDGCWRRATDNYGVVGMASRnpLKDGVNQILGRDSFHQGVVIRQQDNGIAVDVYIIVGYGTKISAVSKSV 89
Cdd:COG1302    7 GKITIADEVIAKIAGIAALEVYGVVGMAGG--FADGIAELLGRKNLTKGVKVEVGEDQVAIDLYVVVEYGVNIPEVAENV 84

                         90       100       110
                 ....*....|....*....|....*....|.
gi 930084891  90 QEKVKYNLEAMLGVTANSVNIMVQGVRVLGD 120
Cdd:COG1302   85 QENVKYAVEKMTGLEVVEVNVHVQGVRFPEE 115
 
Name Accession Description Interval E-value
YloU COG1302
Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family [Function ...
 10-120 1.81e-29

Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family [Function unknown];


Pssm-ID: 440913  Cd Length: 118  Bit Score: 102.55  E-value: 1.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 930084891  10 GMIDIANDVICDGCWRRATDNYGVVGMASRnpLKDGVNQILGRDSFHQGVVIRQQDNGIAVDVYIIVGYGTKISAVSKSV 89
Cdd:COG1302    7 GKITIADEVIAKIAGIAALEVYGVVGMAGG--FADGIAELLGRKNLTKGVKVEVGEDQVAIDLYVVVEYGVNIPEVAENV 84

                         90       100       110
                 ....*....|....*....|....*....|.
gi 930084891  90 QEKVKYNLEAMLGVTANSVNIMVQGVRVLGD 120
Cdd:COG1302   85 QENVKYAVEKMTGLEVVEVNVHVQGVRFPEE 115
Asp23 pfam03780
Asp23 family, cell envelope-related function; The alkaline shock protein Asp23 was identified ...
 10-116 9.79e-28

Asp23 family, cell envelope-related function; The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria. UniProtKB:Q2FW64.


Pssm-ID: 427500  Cd Length: 108  Bit Score: 97.97  E-value: 9.79e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 930084891   10 GMIDIANDVICDGCWRRATDNYGVVGMASRnpLKDGVNQILGRDSFHQGVVIRQQDNG-IAVDVYIIVGYGTKISAVSKS 88
Cdd:pfam03780   3 GEITIADEVIAKIAGIAATEVDGVVGMAGG--LKDGLAERLGRENLTKGVKVEVGEEGqVAVDLYVIVEYGVSIPEVAEN 80

                          90       100
                  ....*....|....*....|....*...
gi 930084891   89 VQEKVKYNLEAMLGVTANSVNIMVQGVR 116
Cdd:pfam03780  81 IQENVKYAVETMTGLEVVEVNVHVQGVR 108
 
Name Accession Description Interval E-value
YloU COG1302
Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family [Function ...
 10-120 1.81e-29

Uncharacterized conserved protein YloU, alkaline shock protein (Asp23) family [Function unknown];


Pssm-ID: 440913  Cd Length: 118  Bit Score: 102.55  E-value: 1.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 930084891  10 GMIDIANDVICDGCWRRATDNYGVVGMASRnpLKDGVNQILGRDSFHQGVVIRQQDNGIAVDVYIIVGYGTKISAVSKSV 89
Cdd:COG1302    7 GKITIADEVIAKIAGIAALEVYGVVGMAGG--FADGIAELLGRKNLTKGVKVEVGEDQVAIDLYVVVEYGVNIPEVAENV 84

                         90       100       110
                 ....*....|....*....|....*....|.
gi 930084891  90 QEKVKYNLEAMLGVTANSVNIMVQGVRVLGD 120
Cdd:COG1302   85 QENVKYAVEKMTGLEVVEVNVHVQGVRFPEE 115
Asp23 pfam03780
Asp23 family, cell envelope-related function; The alkaline shock protein Asp23 was identified ...
 10-116 9.79e-28

Asp23 family, cell envelope-related function; The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria. UniProtKB:Q2FW64.


Pssm-ID: 427500  Cd Length: 108  Bit Score: 97.97  E-value: 9.79e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 930084891   10 GMIDIANDVICDGCWRRATDNYGVVGMASRnpLKDGVNQILGRDSFHQGVVIRQQDNG-IAVDVYIIVGYGTKISAVSKS 88
Cdd:pfam03780   3 GEITIADEVIAKIAGIAATEVDGVVGMAGG--LKDGLAERLGRENLTKGVKVEVGEEGqVAVDLYVIVEYGVSIPEVAEN 80

                          90       100
                  ....*....|....*....|....*...
gi 930084891   89 VQEKVKYNLEAMLGVTANSVNIMVQGVR 116
Cdd:pfam03780  81 IQENVKYAVETMTGLEVVEVNVHVQGVR 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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