|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
4-371 |
0e+00 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 663.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 4 KGKKFKKRYLVIILILLVGGMAGWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDN 83
Cdd:PRK11578 3 KRKKVKKRYLIALVIVLAGGITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 84 VKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATEMAVKQARIGT 163
Cdd:PRK11578 83 VKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAATELAVKQAQIGT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 164 IDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRAGQK 243
Cdd:PRK11578 163 IDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 244 AWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVGGNR 323
Cdd:PRK11578 243 AWFTVLGDPLTRYEGVLKDILPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNR 322
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 919609276 324 YKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGAT 371
Cdd:PRK11578 323 YKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVIIGEAKPGAA 370
|
|
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
42-363 |
7.61e-76 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 237.15 E-value: 7.61e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 42 VRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLmelnaerQQAAA 121
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQL-------AAAQA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 122 ELKLARVTLARQQQLAKTQAVSQQDLDTAATEMAVKQarigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTL 201
Cdd:COG0845 76 QLELAKAELERYKALLKKGAVSQQELDQAKAALDQAQ-------AALAAAQAALEQARANLAYTTIRAPFDGVVGERNVE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 202 QGQTVIAAQQapnILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEkiNDAIFYYARFE 281
Cdd:COG0845 149 PGQLVSAGTP---LFTIADLDPLEVEFDVPESDLARLKVGQPVTVTLDAGPGKTFEGKVTFIDPAVD--PATRTVRVRAE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 282 VPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEpvGGNRYKVALLRNGEK-REREVVIGERNDTDVEVVKGLEAGDE 360
Cdd:COG0845 224 LPNPDGLLRPGMFVRVRIVLGERENALLVPASAVVR--DGGGAYVFVVDADGKvERRPVTLGRRDGDQVEVLSGLKAGDR 301
|
...
gi 919609276 361 VII 363
Cdd:COG0845 302 VVV 304
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
39-363 |
9.48e-52 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 174.81 E-value: 9.48e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 39 TLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDqaenqikEVEATLMELNAERQQ 118
Cdd:TIGR01730 3 VATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDD-------DYQLALQAALAQLAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 119 AAAELKLARVTLARQQQLAKTQAVSQQDLDTAatEMAVKQARigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQI 198
Cdd:TIGR01730 76 AEAQLELAQRSFERAERLVKRNAVSQADLDDA--KAAVEAAQ-----ADLEAAKASLASAQLNLRYTEIRAPFDGTIGRR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 199 TTLQGQTVIAAQqapNILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYA 278
Cdd:TIGR01730 149 LVEVGAYVTAGQ---TLATIVDLDPLEADFSVPERDLPQLRRGQTLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVRA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 279 RFevPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEpvGGNRYKVALLRNGEK-REREVVIGERNDTDVEVVKGLEA 357
Cdd:TIGR01730 226 TF--PNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIE--DLNGKYVYVVKNDGKvSKRPVEVGLRNGGYVEIESGLKA 301
|
....*.
gi 919609276 358 GDEVII 363
Cdd:TIGR01730 302 GDQIVT 307
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
44-244 |
5.35e-15 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 75.15 E-value: 5.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 44 PGDLEQSVLATGKLDALRKVD-VGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAE 122
Cdd:pfam00529 1 LAPLTKGVEAPGRVVVSGNAKaVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 123 LKlarvtlaRQQQLAKTQAVSQQDLDTAATemAVKQARigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQ 202
Cdd:pfam00529 81 LD-------RLQALESELAISRQDYDGATA--QLRAAQ-----AAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTA 146
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 919609276 203 GQTVIAAQQAPNIlTLADMSTMLVKAQVSEADVIHLRAGQKA 244
Cdd:pfam00529 147 GALVAQAQANLLA-TVAQLDQIYVQITQSAAENQAEVRSELS 187
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
4-371 |
0e+00 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 663.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 4 KGKKFKKRYLVIILILLVGGMAGWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDN 83
Cdd:PRK11578 3 KRKKVKKRYLIALVIVLAGGITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 84 VKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATEMAVKQARIGT 163
Cdd:PRK11578 83 VKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAATELAVKQAQIGT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 164 IDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRAGQK 243
Cdd:PRK11578 163 IDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 244 AWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVGGNR 323
Cdd:PRK11578 243 AWFTVLGDPLTRYEGVLKDILPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNR 322
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 919609276 324 YKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGAT 371
Cdd:PRK11578 323 YKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVIIGEAKPGAA 370
|
|
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
42-363 |
7.61e-76 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 237.15 E-value: 7.61e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 42 VRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLmelnaerQQAAA 121
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQL-------AAAQA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 122 ELKLARVTLARQQQLAKTQAVSQQDLDTAATEMAVKQarigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTL 201
Cdd:COG0845 76 QLELAKAELERYKALLKKGAVSQQELDQAKAALDQAQ-------AALAAAQAALEQARANLAYTTIRAPFDGVVGERNVE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 202 QGQTVIAAQQapnILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEkiNDAIFYYARFE 281
Cdd:COG0845 149 PGQLVSAGTP---LFTIADLDPLEVEFDVPESDLARLKVGQPVTVTLDAGPGKTFEGKVTFIDPAVD--PATRTVRVRAE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 282 VPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEpvGGNRYKVALLRNGEK-REREVVIGERNDTDVEVVKGLEAGDE 360
Cdd:COG0845 224 LPNPDGLLRPGMFVRVRIVLGERENALLVPASAVVR--DGGGAYVFVVDADGKvERRPVTLGRRDGDQVEVLSGLKAGDR 301
|
...
gi 919609276 361 VII 363
Cdd:COG0845 302 VVV 304
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
39-363 |
9.48e-52 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 174.81 E-value: 9.48e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 39 TLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDqaenqikEVEATLMELNAERQQ 118
Cdd:TIGR01730 3 VATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDD-------DYQLALQAALAQLAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 119 AAAELKLARVTLARQQQLAKTQAVSQQDLDTAatEMAVKQARigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQI 198
Cdd:TIGR01730 76 AEAQLELAQRSFERAERLVKRNAVSQADLDDA--KAAVEAAQ-----ADLEAAKASLASAQLNLRYTEIRAPFDGTIGRR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 199 TTLQGQTVIAAQqapNILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYA 278
Cdd:TIGR01730 149 LVEVGAYVTAGQ---TLATIVDLDPLEADFSVPERDLPQLRRGQTLTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVRA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 279 RFevPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEpvGGNRYKVALLRNGEK-REREVVIGERNDTDVEVVKGLEA 357
Cdd:TIGR01730 226 TF--PNPDGRLLPGMFGRVTISLKVRSSAIVVPTQAVIE--DLNGKYVYVVKNDGKvSKRPVEVGLRNGGYVEIESGLKA 301
|
....*.
gi 919609276 358 GDEVII 363
Cdd:TIGR01730 302 GDQIVT 307
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
9-301 |
3.50e-44 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 155.21 E-value: 3.50e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 9 KKRYLVIILILLVGGMAGWrminaplptyqtlIVRPGDLEQSVLATGKLDAlRKVDVGAQVSGQLKTLLVSIGDNVKKDQ 88
Cdd:COG1566 6 KRRLLALVLLLLALGLALW-------------AAGRNGPDEPVTADGRVEA-RVVTVAAKVSGRVTEVLVKEGDRVKKGQ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 89 LLGVIDP-------DQAENQIKEVEATLMELNAER-------------QQAAAELKLARVTLARQQQLAKTQAVSQQDLD 148
Cdd:COG1566 72 VLARLDPtdlqaalAQAEAQLAAAEAQLARLEAELgaeaeiaaaeaqlAAAQAQLDLAQRELERYQALYKKGAVSQQELD 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 149 TAATEMAVKQAR--------------------IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIA 208
Cdd:COG1566 152 EARAALDAAQAQleaaqaqlaqaqaglreeeeLAAAQAQVAQAEAALAQAELNLARTTIRAPVDGVVTNLNVEPGEVVSA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 209 AQQapnILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEKI--------NDAIFYYARF 280
Cdd:COG1566 232 GQP---LLTIVPLDDLWVEAYVPETDLGRVKPGQPVEVRVDAYPDRVFEGKVTSISPGAGFTsppknatgNVVQRYPVRI 308
|
330 340
....*....|....*....|..
gi 919609276 281 EVPNP-KRILRLDMTAQVYIQL 301
Cdd:COG1566 309 RLDNPdPEPLRPGMSATVEIDT 330
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
22-362 |
9.34e-23 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 98.71 E-value: 9.34e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 22 GGMAGWRMinAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQ 101
Cdd:PRK11556 49 GGRRGMRS--GPLAPVQAATATEQAVPRYLTGLGTVTAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 102 IKEVEATLmelnAERQqaaAELKLARVTLARQQQLAKTQAVSQQDLDTaatemavKQARIGTIDAQIKRNRASLDTAKTN 181
Cdd:PRK11556 127 LAQAQGQL----AKDQ---ATLANARRDLARYQQLAKTNLVSRQELDA-------QQALVSETEGTIKADEASVASAQLQ 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 182 LEYTRIVAPMAGEV--------TQITTlqGQT---VIAAQQAP--NILTL--ADMSTMLvKAQVSEADVIhlragQKAWf 246
Cdd:PRK11556 193 LDYSRITAPISGRVglkqvdvgNQISS--GDTtgiVVITQTHPidLVFTLpeSDIATVV-QAQKAGKPLV-----VEAW- 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 247 tIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFevPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEpvgGNRYKV 326
Cdd:PRK11556 264 -DRTNSKKLSEGTLLSLDNQIDATTGTIKLKARF--NNQDDALFPNQFVNARMLVDTLQNAVVIPTAALQM---GNEGHF 337
|
330 340 350
....*....|....*....|....*....|....*...
gi 919609276 327 ALLRNGEKR--EREVVIGERNDTDVEVVKGLEAGDEVI 362
Cdd:PRK11556 338 VWVLNDENKvsKHLVTPGIQDSQKVVISAGLSAGDRVV 375
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
3-263 |
1.92e-20 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 91.24 E-value: 1.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 3 AKGKKFKKRYLVII--LILLVGGMAGWRMINAPLPTyqtlivrpgdleqsvlaTGKLDAlRKVDVGAQVSGQLKTLLVSI 80
Cdd:PRK10476 5 PKKSPRKKLPALAIvaLAIVALVFVIWRTDSAPSTD-----------------DAYIDA-DVVHVASEVGGRIVELAVTE 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 81 GDNVKKDQLLGVIDP-------DQAENQIKEVEATLM----ELNAER----------QQAAAELKLARVTLARQQQLAKT 139
Cdd:PRK10476 67 NQAVKKGDLLFRIDPrpyeltvAQAQADLALADAQIMttqrSVDAERsnaasaneqvERARANAKLATRTLERLEPLLAK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 140 QAVSQQDLDTAAT-----EMAVKQAR---------IGTID---AQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQ 202
Cdd:PRK10476 147 GYVSAQQVDQARTaqrdaEVSLNQALlqaqaaaaaVGGVDalvAQRAAREAALAIAELHLEDTTVRAPFDGRVVGLKVSV 226
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 919609276 203 GQTVIAAQqapNILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDI 263
Cdd:PRK10476 227 GEFAAPMQ---PIFTLIDTDHWYAIANFRETDLKNIRVGDCATVYSMIDRGRPFEGKVDSI 284
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
7-268 |
1.98e-17 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 82.32 E-value: 1.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 7 KFKKRYLVIILILLVGGMAGWRMinaplptYQtlivrpGDLEQSVLATGKLDaLRKVDVGAQVSGQLKTLLVSIGDNVKK 86
Cdd:PRK03598 2 KKKVVIGLAVVVLAAAVAGGWWW-------YQ------SRQDNGLTLYGNVD-IRTVNLGFRVGGRLASLAVDEGDAVKA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 87 DQLLGVIDP-------DQAENQIKEVEATLMELNA-----ERQQAAAELKLARVTL-------ARQQQLAKTQAVSQQDL 147
Cdd:PRK03598 68 GQVLGELDAapyenalMQAKANVSVAQAQLDLMLAgyrdeEIAQARAAVKQAQAAYdyaqnfyNRQQGLWKSRTISANDL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 148 DTAATEMAVKQAR-------------------IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGqTVIA 208
Cdd:PRK03598 148 ENARSSRDQAQATlksaqdklsqyregnrpqdIAQAKASLAQAQAALAQAELNLQDTELIAPSDGTILTRAVEPG-TMLN 226
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 209 AQQApnILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPE 268
Cdd:PRK03598 227 AGST--VFTLSLTRPVWVRAYVDERNLGQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAE 284
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
32-369 |
3.37e-16 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 79.37 E-value: 3.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 32 APLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLme 111
Cdd:PRK09859 31 AMTPEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELNSAKGSL-- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 112 lnAERQQAAAElklARVTLARQQQLAKTQAVSQQDLDTAATEMavkqariGTIDAQIKRNRASLDTAKTNLEYTRIVAPM 191
Cdd:PRK09859 109 --AKALSTASN---ARITFNRQASLLKTNYVSRQDYDTARTQL-------NEAEANVTVAKAAVEQATINLQYANVTSPI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 192 AGeVTQITTLQGQTVIAAQQAPNILTLADMSTMLV------------KAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGV 259
Cdd:PRK09859 177 TG-VSGKSSVTVGALVTANQADSLVTVQRLDPIYVdltqsvqdflrmKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGT 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 260 LKDILPTPEKINDAIFYYARFevPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVGGNRYKVALLRNGEKREREV 339
Cdd:PRK09859 256 LKFSDPTVDETTGSVTLRAIF--PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREI 333
|
330 340 350
....*....|....*....|....*....|...
gi 919609276 340 VIGERNDTDVEVVKGLEAGDEVIIG---ESRPG 369
Cdd:PRK09859 334 EASKAIGDQWVVTSGLQAGDRVIVSglqRIRPG 366
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
44-244 |
5.35e-15 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 75.15 E-value: 5.35e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 44 PGDLEQSVLATGKLDALRKVD-VGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAE 122
Cdd:pfam00529 1 LAPLTKGVEAPGRVVVSGNAKaVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 123 LKlarvtlaRQQQLAKTQAVSQQDLDTAATemAVKQARigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQ 202
Cdd:pfam00529 81 LD-------RLQALESELAISRQDYDGATA--QLRAAQ-----AAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTA 146
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 919609276 203 GQTVIAAQQAPNIlTLADMSTMLVKAQVSEADVIHLRAGQKA 244
Cdd:pfam00529 147 GALVAQAQANLLA-TVAQLDQIYVQITQSAAENQAEVRSELS 187
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
34-370 |
2.78e-14 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 73.59 E-value: 2.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 34 LPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLmeln 113
Cdd:PRK15030 37 MPAVGVVTVKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDSAKGDL---- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 114 aERQQAAAelKLARVTLARQQQLAKTQAVSQQDLDTAATEmaVKQArigtiDAQIKRNRASLDTAKTNLEYTRIVAPMAG 193
Cdd:PRK15030 113 -AKAQAAA--NIAQLTVNRYQKLLGTQYISKQEYDQALAD--AQQA-----NAAVTAAKAAVETARINLAYTKVTSPISG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 194 EVTQITTLQGqTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRA-----------GQKAWFTIAGD----PQTryeG 258
Cdd:PRK15030 183 RIGKSNVTEG-ALVQNGQATALATVQQLDPIYVDVTQSSNDFLRLKQelangtlkqenGKAKVSLITSDgikfPQD---G 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 259 VLKDILPTPEKINDAIFYYARFevPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVGGNRYKVALLRNGEKRERE 338
Cdd:PRK15030 259 TLEFSDVTVDQTTGSITLRAIF--PNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVETRP 336
|
330 340 350
....*....|....*....|....*....|....*
gi 919609276 339 VVIGERNDTDVEVVKGLEAGDEVIIG---ESRPGA 370
Cdd:PRK15030 337 IVASQAIGDKWLVTEGLKAGDRVVISglqKVRPGV 371
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
46-295 |
1.79e-13 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 68.69 E-value: 1.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 46 DLEQSVLATGKL--DALRKVDVGAQVSGQLKTLLV-SIGDNVKKDQLLGVID-PD----QAE----NQIKEVEATLMELN 113
Cdd:pfam16576 1 PLSRTIRAVGRVayDERRLAHVHARVEGWIEKLYVnATGDPVKKGQPLAELYsPElvaaQQEyllaLRSGDALSKSELLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 114 AERQQaaaeLKLARVTLARQQQLAKTQAVSQqdldtaatemavkqarigtidaqikrnrasldtaktnleYTRIVAPMAG 193
Cdd:pfam16576 81 AARQR----LRLLGMPEAQIAELERTGKVQP---------------------------------------TVTVYAPISG 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 194 EVTQITTLQGQTVIAAQqapNILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEKINDA 273
Cdd:pfam16576 118 VVTELNVREGMYVQPGD---TLFTIADLSTVWVEADVPEQDLALVKVGQPAEVTLPALPGKTFEGKVDYIYPTLDPKTRT 194
|
250 260
....*....|....*....|..
gi 919609276 274 IfyYARFEVPNPKRILRLDMTA 295
Cdd:pfam16576 195 V--RVRIELPNPDGRLKPGMFA 214
|
|
| heterocyst_DevB |
TIGR02971 |
ABC exporter membrane fusion protein, DevB family; Members of this protein family are found ... |
73-244 |
4.27e-13 |
|
ABC exporter membrane fusion protein, DevB family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. DevB from Anabaena sp. strain PCC 7120 is partially characterized as a membrane fusion protein of the DevBCA ABC exporter, probably a glycolipid exporter, required for heterocyst formation. Most Cyanobacteria have one member only, but Nostoc sp. PCC 7120 has seven members.
Pssm-ID: 213754 [Multi-domain] Cd Length: 327 Bit Score: 69.47 E-value: 4.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 73 LKTLLVSIGDNVKKDQLLGVIDP--------DQAENQIKEVEATLMELNAERQQAA------------------------ 120
Cdd:TIGR02971 27 IKKLLVAEGDRVQAGQVLAELDSrpertaelDVARTQLDEAKARLAQVRAGAKKGEiaaqraaraaaklfkdvaaqqatl 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 121 ----AELKLARVTLARQQQLAKTQAVSQQDLD------------------------------TAATEMAVKQARIGTIDA 166
Cdd:TIGR02971 107 nrleAELETAQREVDRYRSLFRDGAVSASDLDskalklrtaeeeleealasrseqidgaraaLASLAEEVRETDVDLAQA 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 919609276 167 QIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTViaaqQAPNILTLADMSTMLVKAQVSEADVIHLRAGQKA 244
Cdd:TIGR02971 187 EVKSALEAVQQAEALLELTYVKAPIDGRVLKIHAREGEVI----GSEGILEMGDTSQMYAVAEVYETDINRVRVGQRA 260
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
5-363 |
6.48e-12 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 66.36 E-value: 6.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 5 GKKFKKRYLVIILILLVGGMAGWR-----MINAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVS 79
Cdd:PRK09578 1 YEWARRRRLLLAALVALFVLAGCGkgdsdAAAAAPREATVVTVRPTSVPMTVELPGRLDAYRQAEVRARVAGIVTARTYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 80 IGDNVKKDQLLGVIDPDQaenqikeveatlmeLNAERQQAAAELKLARVT-------LARQQQLAKTQAVSQQDLDTAAT 152
Cdd:PRK09578 81 EGQEVKQGAVLFRIDPAP--------------LKAARDAAAGALAKAEAAhlaaldkRRRYDDLVRDRAVSERDYTEAVA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 153 EMavKQARigtidAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTViaAQQAPNILTLAD-MSTMLVKAQVS 231
Cdd:PRK09578 147 DE--RQAK-----AAVASAKAELARAQLQLDYATVTAPIDGRARRALVTEGALV--GQDQATPLTTVEqLDPIYVNFSQP 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 232 EADVIHLRAGQKAWfTIAGDPQTRYEG--VLKDILPTPEK------------INDAIFYYARFevPNPKRILRLDMTAQV 297
Cdd:PRK09578 218 AADVEALRRAVKSG-RATGIAQQDVAVtlVRADGSEYPLKgkllfsdlavdpTTDTVAMRALF--PNPERELLPGAYVRI 294
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 919609276 298 YIQLMDVKNVLIIPLAALGEPVGGNRYKVaLLRNGEKREREVVIGERNDTDVEVVKGLEAGDEVII 363
Cdd:PRK09578 295 ALDRAVNPRAILVPRDALLRTADSASVKV-VGQNGKVRDVEVEADQMSGRDWIVTRGLAGGERVIV 359
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
186-290 |
1.09e-10 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 58.14 E-value: 1.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 186 RIVAPMAGEVTQITTLQGQtVIAAQQapNILTLADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILP 265
Cdd:pfam13437 1 TIRAPVDGVVAELNVEEGQ-VVQAGD--PLATIVPPDRLLVEAFVPAADLGSLKKGQKVTLKLDPGSDYTLEGKVVRISP 77
|
90 100
....*....|....*....|....*
gi 919609276 266 TPEKINDAIFYYARFEVPNPKRILR 290
Cdd:pfam13437 78 TVDPDTGVIPVRVSIENPKTPIPLL 102
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
63-204 |
3.45e-08 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 54.36 E-value: 3.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 63 VDVGAQVSGQLKTllVSIGDN--VKKDQLLGVIDPDQAENQIKEVEAtlmelNAERQQAAAELKlaRVTLARQQQLAkTQ 140
Cdd:PRK10559 48 VAIAPDVSGLITQ--VNVHDNqlVKKGQVLFTIDQPRYQKALAEAEA-----DVAYYQVLAQEK--RREAGRRNRLG-VQ 117
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 919609276 141 AVSQQDLDTAATEMAvkqarigTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQ 204
Cdd:PRK10559 118 AMSREEIDQANNVLQ-------TVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGE 174
|
|
| PRK15136 |
PRK15136 |
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA; |
6-251 |
4.68e-06 |
|
multidrug efflux MFS transporter periplasmic adaptor subunit EmrA;
Pssm-ID: 185090 [Multi-domain] Cd Length: 390 Bit Score: 48.15 E-value: 4.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 6 KKFKKRYLVIILILLVggmagWRMINAPLPTYQTLIVRPGDLEQSVLATGKldalrKVDVGAQVSGQLKTLLVSIGDNVK 85
Cdd:PRK15136 15 KKKGKRKRALLLLTLL-----FIIIGVAYGIYWFLVLRHHQETDDAYVAGN-----QVQIMSQVSGSVTKVWADNTDFVK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 86 KDQLLGVIDPDQAENQIKEVEATLME---------LNAERQQAAAELK---LARVT--LARQQQLAKTQAVSQQDLDTAA 151
Cdd:PRK15136 85 EGDVLVTLDPTDAEQAFEKAKTALANsvrqthqlmINSKQYQANIELQktaLAQAQsdLNRRVPLGNANLIGREELQHAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 152 TEMAVKQARIGTIDAQIKRNRAS-LDT-----------------AKTNLEYTRIVAPMAGEVTQiTTLQgqtvIAAQQAP 213
Cdd:PRK15136 165 DAVASAQAQLDVAIQQYNANQAMiLNTpledqpavqqaatevrnAWLALQRTKIVSPMTGYVSR-RSVQ----VGAQISP 239
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 919609276 214 N--ILTLADMSTMLVKAQVSEADVIHLRAGQKAwfTIAGD 251
Cdd:PRK15136 240 TtpLMAVVPATNLWVDANFKETQLANMRIGQPA--TITSD 277
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
61-109 |
1.02e-04 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 39.35 E-value: 1.02e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 919609276 61 RKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATL 109
Cdd:pfam13533 1 PVVKIASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQLQLQQAEAQL 49
|
|
| type_I_hlyD |
TIGR01843 |
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport ... |
98-259 |
1.76e-04 |
|
type I secretion membrane fusion protein, HlyD family; Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 130902 [Multi-domain] Cd Length: 423 Bit Score: 43.07 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 98 AENQIKEVEATLMELNAERQQAAAELklarvtLARQQQLAKTQAVSQQDLDTAATEMavkQARIGTIDAQIKRNRASLDT 177
Cdd:TIGR01843 201 LERERAEAQGELGRLEAELEVLKRQI------DELQLERQQIEQTFREEVLEELTEA---QARLAELRERLNKARDRLQR 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 178 AKtnleytrIVAPMAGEVTQIT-TLQGQTVIAAQQAPNILTLADmsTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRY 256
Cdd:TIGR01843 272 LI-------IRSPVDGTVQSLKvHTVGGVVQPGETLMEIVPEDD--PLEIEAKLSPKDIGFVHVGQPAEIKFSAFPYRRY 342
|
...
gi 919609276 257 EGV 259
Cdd:TIGR01843 343 GIL 345
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
96-241 |
2.49e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 39.75 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 919609276 96 DQAENQIKEVEatlmelNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATEMAVKQARIGTIDAQIKRNRASL 175
Cdd:COG4717 149 EELEERLEELR------ELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 919609276 176 DTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQqapnILTLADMSTMLVKAQVSEADVIHLRAG 241
Cdd:COG4717 223 EELEEELEQLENELEAAALEERLKEARLLLLIAAA----LLALLGLGGSLLSLILTIAGVLFLVLG 284
|
|
| |
