NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|700189430|gb|KGN44663|]
View 

hypothetical protein Csa_015732 [Cucumis sativus]

Protein Classification

CBM9 family sugar-binding protein; cytochrome and DOMON domain-containing protein( domain architecture ID 10176446)

sugar-binding protein similar to Carbohydrate family 9 binding domain (CBM9-2); cytochrome and DOMON domain-containing protein may bind heme and participate in electron transport reactions

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DOMON_CIL1_like cd09629
DOMON-like domain of Brassica carinata CIL1 and similar proteins; Brassica carinata CIL1 has ...
 36-188 4.66e-61

DOMON-like domain of Brassica carinata CIL1 and similar proteins; Brassica carinata CIL1 has been described as involved in suppression of axillary meristem development. It contains a single DOMON domain, the function of which is unclear. Members in this diverse family of plant proteins may have a cytochrome b561 domain C-terminal to the DOMON domain, some members from Arabidopsis have been characterized as auxin-responsive or auxin-induced proteins. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.


:

Pssm-ID: 187687  Cd Length: 152  Bit Score: 189.40  E-value: 4.66e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430  36 FTNCQDLPYLHAFLHWSYNPKNSSLSIAFLAPPPTTAGWVAWAVNPTATGMAGSQAFLAafF---TKSLTVRTFNITSYN 112
Cdd:cd09629    1 FAACNDLPTLGASLHWTYNASNSTLDVAFRATPPSSSGWVAWGINPTGTGMVGTQALVA--FrnsNGSVLVYTYNITSYT 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700189430 113 SVRPSPTLSFPFWDLASQSSDDLFAIFVTVKVPEKSSSLNQVWQVGASVDSsmGVPAVHEFKPDNLKSRGVLVFDG 188
Cdd:cd09629   79 KLGEPLPLSFDVSDLSAEYSGGEMTIFATLKLPSNLTSVNHVWQVGPAVTG--GSPGPHPTSGANLASKGTLDLLT 152
 
Name Accession Description Interval E-value
DOMON_CIL1_like cd09629
DOMON-like domain of Brassica carinata CIL1 and similar proteins; Brassica carinata CIL1 has ...
 36-188 4.66e-61

DOMON-like domain of Brassica carinata CIL1 and similar proteins; Brassica carinata CIL1 has been described as involved in suppression of axillary meristem development. It contains a single DOMON domain, the function of which is unclear. Members in this diverse family of plant proteins may have a cytochrome b561 domain C-terminal to the DOMON domain, some members from Arabidopsis have been characterized as auxin-responsive or auxin-induced proteins. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.


Pssm-ID: 187687  Cd Length: 152  Bit Score: 189.40  E-value: 4.66e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430  36 FTNCQDLPYLHAFLHWSYNPKNSSLSIAFLAPPPTTAGWVAWAVNPTATGMAGSQAFLAafF---TKSLTVRTFNITSYN 112
Cdd:cd09629    1 FAACNDLPTLGASLHWTYNASNSTLDVAFRATPPSSSGWVAWGINPTGTGMVGTQALVA--FrnsNGSVLVYTYNITSYT 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700189430 113 SVRPSPTLSFPFWDLASQSSDDLFAIFVTVKVPEKSSSLNQVWQVGASVDSsmGVPAVHEFKPDNLKSRGVLVFDG 188
Cdd:cd09629   79 KLGEPLPLSFDVSDLSAEYSGGEMTIFATLKLPSNLTSVNHVWQVGPAVTG--GSPGPHPTSGANLASKGTLDLLT 152
DUF568 pfam04526
Protein of unknown function (DUF568); Family of uncharacterized plant proteins.
 86-186 2.97e-26

Protein of unknown function (DUF568); Family of uncharacterized plant proteins.


Pssm-ID: 461343  Cd Length: 100  Bit Score: 98.49  E-value: 2.97e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430   86 MAGSQAFLAafFTKS---LTVRTFNITSYNSVRPSPtLSFPFWDLASQSSDDLFAIFVTVKVPE-KSSSLNQVWQVGASV 161
Cdd:pfam04526   1 MVGAQALIA--FDPSngsVVVKTYNLTSYTGISEPD-LSFDVSDLSAEYSGGEMTIFATLKLPPgNSTTVNHVWQVGPSV 77

                          90       100
                  ....*....|....*....|....*
gi 700189430  162 DSsmGVPAVHEFKPDNLKSRGVLVF 186
Cdd:pfam04526  78 SG--GSPAIHPTSGDNLNSKGTLDL 100
DoH smart00664
Possible catecholamine-binding domain present in a variety of eukaryotic proteins; A ...
 48-180 1.27e-09

Possible catecholamine-binding domain present in a variety of eukaryotic proteins; A predominantly beta-sheet domain present as a regulatory N-terminal domain in dopamine beta-hydroxylase, mono-oxygenase X and SDR2. Its function remains unknown at present (Ponting, Human Molecular Genetics, in press).


Pssm-ID: 214768  Cd Length: 148  Bit Score: 55.51  E-value: 1.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430    48 FLHWSYNPKNSslsIAF-LAPPPTTAGWVAWAVNPTaTGMAGSQAFLAAFFTKS-LTVRTFNITSYNSvrPSPTLSFPFW 125
Cdd:smart00664   5 FLSWSVDGENS---IAFeLSGPTSTNGWVAIGFSPD-GQMAGADVVVAWVDNNGrVTVKDYYTPGYGP--PVEDDQQDVT 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 700189430   126 DLASQSSDD--LFAIF-VTVKVPEK------SSSLNQVWQVGAsvDSSMGVPAVHEFKPDNLKS 180
Cdd:smart00664  79 DLLSATYENgvLTCRFrRKLGSNDPddksllDGTVHVLWAKGP--LSPNGGLGYHDFSLKSTKK 140
 
Name Accession Description Interval E-value
DOMON_CIL1_like cd09629
DOMON-like domain of Brassica carinata CIL1 and similar proteins; Brassica carinata CIL1 has ...
 36-188 4.66e-61

DOMON-like domain of Brassica carinata CIL1 and similar proteins; Brassica carinata CIL1 has been described as involved in suppression of axillary meristem development. It contains a single DOMON domain, the function of which is unclear. Members in this diverse family of plant proteins may have a cytochrome b561 domain C-terminal to the DOMON domain, some members from Arabidopsis have been characterized as auxin-responsive or auxin-induced proteins. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.


Pssm-ID: 187687  Cd Length: 152  Bit Score: 189.40  E-value: 4.66e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430  36 FTNCQDLPYLHAFLHWSYNPKNSSLSIAFLAPPPTTAGWVAWAVNPTATGMAGSQAFLAafF---TKSLTVRTFNITSYN 112
Cdd:cd09629    1 FAACNDLPTLGASLHWTYNASNSTLDVAFRATPPSSSGWVAWGINPTGTGMVGTQALVA--FrnsNGSVLVYTYNITSYT 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 700189430 113 SVRPSPTLSFPFWDLASQSSDDLFAIFVTVKVPEKSSSLNQVWQVGASVDSsmGVPAVHEFKPDNLKSRGVLVFDG 188
Cdd:cd09629   79 KLGEPLPLSFDVSDLSAEYSGGEMTIFATLKLPSNLTSVNHVWQVGPAVTG--GSPGPHPTSGANLASKGTLDLLT 152
DUF568 pfam04526
Protein of unknown function (DUF568); Family of uncharacterized plant proteins.
 86-186 2.97e-26

Protein of unknown function (DUF568); Family of uncharacterized plant proteins.


Pssm-ID: 461343  Cd Length: 100  Bit Score: 98.49  E-value: 2.97e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430   86 MAGSQAFLAafFTKS---LTVRTFNITSYNSVRPSPtLSFPFWDLASQSSDDLFAIFVTVKVPE-KSSSLNQVWQVGASV 161
Cdd:pfam04526   1 MVGAQALIA--FDPSngsVVVKTYNLTSYTGISEPD-LSFDVSDLSAEYSGGEMTIFATLKLPPgNSTTVNHVWQVGPSV 77

                          90       100
                  ....*....|....*....|....*
gi 700189430  162 DSsmGVPAVHEFKPDNLKSRGVLVF 186
Cdd:pfam04526  78 SG--GSPAIHPTSGDNLNSKGTLDL 100
DoH smart00664
Possible catecholamine-binding domain present in a variety of eukaryotic proteins; A ...
 48-180 1.27e-09

Possible catecholamine-binding domain present in a variety of eukaryotic proteins; A predominantly beta-sheet domain present as a regulatory N-terminal domain in dopamine beta-hydroxylase, mono-oxygenase X and SDR2. Its function remains unknown at present (Ponting, Human Molecular Genetics, in press).


Pssm-ID: 214768  Cd Length: 148  Bit Score: 55.51  E-value: 1.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 700189430    48 FLHWSYNPKNSslsIAF-LAPPPTTAGWVAWAVNPTaTGMAGSQAFLAAFFTKS-LTVRTFNITSYNSvrPSPTLSFPFW 125
Cdd:smart00664   5 FLSWSVDGENS---IAFeLSGPTSTNGWVAIGFSPD-GQMAGADVVVAWVDNNGrVTVKDYYTPGYGP--PVEDDQQDVT 78

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 700189430   126 DLASQSSDD--LFAIF-VTVKVPEK------SSSLNQVWQVGAsvDSSMGVPAVHEFKPDNLKS 180
Cdd:smart00664  79 DLLSATYENgvLTCRFrRKLGSNDPddksllDGTVHVLWAKGP--LSPNGGLGYHDFSLKSTKK 140
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH