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Conserved domains on  [gi|636385644|gb|KDL62848|]
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DNA replication protein dnaC [Klebsiella variicola]

Protein Classification

DNA replication protein DnaC( domain architecture ID 11482982)

DNA replication protein DnaC is a loading factor that complexes with the C-terminus of helicase DnaB and inhibits it from unwinding the dsDNA at a replication fork; a member of the AAA+ ATPase family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 3-246 7.42e-177

DNA replication protein DnaC; Validated


:

Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 485.81  E-value: 7.42e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   3 MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECEG 82
Cdd:PRK07952   1 MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGRIRSAALERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  83 QMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLSDL 162
Cdd:PRK07952  81 QMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNSETSEEQLLNDL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 163 SKVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV 242
Cdd:PRK07952 161 SNVDLLVIDEIGVQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSRV 240


                 ....
gi 636385644 243 TGKE 246
Cdd:PRK07952 241 TGKE 244
 
Name Accession Description Interval E-value
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 3-246 7.42e-177

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 485.81  E-value: 7.42e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   3 MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECEG 82
Cdd:PRK07952   1 MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGRIRSAALERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  83 QMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLSDL 162
Cdd:PRK07952  81 QMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNSETSEEQLLNDL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 163 SKVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV 242
Cdd:PRK07952 161 SNVDLLVIDEIGVQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSRV 240


                 ....
gi 636385644 243 TGKE 246
Cdd:PRK07952 241 TGKE 244
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-241 7.29e-28

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 106.40  E-value: 7.29e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   1 MSMKNVGDLMKRL-----------QKMMPAHIEPAFktgEELLAwqkeqGRLRSEALERENRamKMQRTFNRSGIRPlhq 69
Cdd:COG1484    1 MLMEELKELLKALklpgmaealdeLLAQAACDELSY---EEFLA-----LLLEAEVAEREQR--RIERRLKAARFPA--- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  70 NCSFDNYRVEC-----EGQMNALARARqYVEEfDGNIasfIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAM 144
Cdd:COG1484   68 AKTLEDFDFDAqpgldRRQILELATLD-FIER-GENL---ILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNEL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 145 KDTFGNRetSEEQLLSDLSKVDLLVIDEIGMQTESRYEKVIINQIVDRRsSSKRPTgMLTnSN--MEEMNKLLGERVM-- 220
Cdd:COG1484  143 KEARADG--RLERLLKRLAKVDLLILDELGYLPLDAEGAELLFELISDR-YERRST-IIT-SNlpFSEWGEVFGDPTLat 217

                        250       260
                 ....*....|....*....|....
gi 636385644 221 ---DRMrLGNSLWVIFNWESYRHR 241
Cdd:COG1484  218 ailDRL-VHHAHIIELKGESYRLK 240
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 41-239 1.52e-18

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 81.36  E-value: 1.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  41 LRSEALERENRAMKM--------------------QRTFNRSGIRPLHQnCSFdnyrvecegqmnaLARARqyveefdgN 100
Cdd:NF038214  35 LEAELAERENRRIERrlkrarfpaaktledfdftaAPGLDKAQIRELAT-LDF-------------IERAE--------N 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 101 IasfIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDtfGNRETSEEQLLSDLSKVDLLVIDEIGMQTESR 180
Cdd:NF038214  93 V---LLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQ--ARADGRLGRLLRRLARYDLLIIDELGYLPFSR 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 636385644 181 YEKVIINQIVDRRsSSKRPTgMLTnSNM--EEMNKLLGERVM-----DRMrLGNSLWVIFNWESYR 239
Cdd:NF038214 168 EGANLLFELIADR-YERGST-IIT-SNLpfSEWGEVFGDPTLaaailDRL-VHHAHILELKGESYR 229
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 97-241 1.12e-14

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 70.94  E-value: 1.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   97 FDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKdtFGNRETSEEQLLSDLSKVDLLVIDEIGMQ 176
Cdd:pfam01695  88 FIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLK--RAHGDGKLTRKLQQLLKPDVLILDEWGYL 165

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  177 TESRYEKVIINQIVDRRsSSKRPTGMLTNSNMEEMNKLLGERVM-----DRMrLGNSLWVIFNWESYRHR 241
Cdd:pfam01695 166 PLDQAEANLLFQVISKR-YEHRSIILTSNLPFGEWGQVFGDAVLatailDRL-LHHCHIVPIKGESYRLK 233
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 82-174 1.34e-13

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 66.40  E-value: 1.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  82 GQMNALARARQYVEEFDGNiaSFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKD--TFGNRETSEEQLL 159
Cdd:cd00009    2 GQEEAIEALREALELPPPK--NLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVaeLFGHFLVRLLFEL 79

                         90
                 ....*....|....*
gi 636385644 160 SDLSKVDLLVIDEIG 174
Cdd:cd00009   80 AEKAKPGVLFIDEID 94
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 105-229 7.40e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.15  E-value: 7.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   105 IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLSD-------------LSKVDLLVID 171
Cdd:smart00382   6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSgelrlrlalalarKLKPDVLILD 85

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 636385644   172 EIGMQTESRYEKVIINQIVDRRSSSKRPTG-----MLTNSNMEEMNKLLGERVMDRMRLGNSL 229
Cdd:smart00382  86 EITSLLDAEQEALLLLLEELRLLLLLKSEKnltviLTTNDEKDLGPALLRRRFDRRIVLLLIL 148
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 13-173 4.98e-08

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 52.92  E-value: 4.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   13 LQKMMPAHIEPAFKTGEEllawqKEQGRLRSEALERENRamkmQRTFNRSGIRPLHQNCSFDNYrVECEGQMNALARARQ 92
Cdd:TIGR00362  59 LQELFGAEIEIEFTVGED-----EEELEPNSKKPEPAPP----EAPAPPSSASGLNPKYTFDNF-VVGKSNRLAHAAALA 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   93 yVEEFDGNIAS--FIFsGKPGTGKNHLAAAICNELLLR--GKSVLIIT----VADIMSAMKdtfgNRETseEQLLSDLSK 164
Cdd:TIGR00362 129 -VAENPGKAYNplFIY-GGVGLGKTHLLHAIGNEILENnpNAKVLYVSsekfTNDFVNALR----NNKM--EEFKEKYRS 200


                  ....*....
gi 636385644  165 VDLLVIDEI 173
Cdd:TIGR00362 201 VDLLLIDDI 209
 
Name Accession Description Interval E-value
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 3-246 7.42e-177

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 485.81  E-value: 7.42e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   3 MKNVGDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECEG 82
Cdd:PRK07952   1 MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGRIRSAALERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  83 QMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLSDL 162
Cdd:PRK07952  81 QMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNSETSEEQLLNDL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 163 SKVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRHRV 242
Cdd:PRK07952 161 SNVDLLVIDEIGVQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSRV 240


                 ....
gi 636385644 243 TGKE 246
Cdd:PRK07952 241 TGKE 244
PRK12377 PRK12377
putative replication protein; Provisional
 3-242 1.77e-106

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 307.92  E-value: 1.77e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   3 MKNV--GDLMKRLQKMMPAHIEPAFKTGEELLAWQKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVEC 80
Cdd:PRK12377   1 MKNIatGGVLERIRRLAPQGVQPPFRTVDEWREWQLAEGRKRSEEINRQNQQLRVEKILNRSGIQPLHRKCSFANYQVQN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  81 EGQMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNREtSEEQLLS 160
Cdd:PRK12377  81 DGQRYALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVTVPDVMSRLHESYDNGQ-SGEKFLQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 161 DLSKVDLLVIDEIGMQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMRLGNSLWVIFNWESYRH 240
Cdd:PRK12377 160 ELCKVDLLVLDEIGIQRETKNEQVVLNQIIDRRTASMRSVGMLTNLNHEAMSTLLGERVMDRMTMNGGRWVNFNWESWRP 239


                 ..
gi 636385644 241 RV 242
Cdd:PRK12377 240 NV 241
PRK08116 PRK08116
hypothetical protein; Validated
 35-246 1.24e-28

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 108.95  E-value: 1.24e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  35 QKEQGRLRSEALERENRAMKMQRTFNRSGIRPLHQNCSFDNYRVEcEGQMNALARARQYVEEFDGNIAS---FIFSGKPG 111
Cdd:PRK08116  46 EREAEEAKEREEENREKQRRIERLKSNSLLDEKFRNSTFENFLFD-KGSEKAYKIARKYVKKFEEMKKEnvgLLLWGSVG 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 112 TGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNR-ETSEEQLLSDLSKVDLLVIDEIGMQTESRYEKVIINQIV 190
Cdd:PRK08116 125 TGKTYLAACIANELIEKGVPVIFVNFPQLLNRIKSTYKSSgKEDENEIIRSLVNADLLILDDLGAERDTEWAREKVYNII 204

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 636385644 191 DRRSSSKRPTGMLTNSNMEEMNKLLGERVMDRMrLGNSLWVIFNWESYRhRVTGKE 246
Cdd:PRK08116 205 DSRYRKGLPTIVTTNLSLEELKNQYGKRIYDRI-LEMCTPVENEGKSYR-KEIAKE 258
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-241 7.29e-28

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 106.40  E-value: 7.29e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   1 MSMKNVGDLMKRL-----------QKMMPAHIEPAFktgEELLAwqkeqGRLRSEALERENRamKMQRTFNRSGIRPlhq 69
Cdd:COG1484    1 MLMEELKELLKALklpgmaealdeLLAQAACDELSY---EEFLA-----LLLEAEVAEREQR--RIERRLKAARFPA--- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  70 NCSFDNYRVEC-----EGQMNALARARqYVEEfDGNIasfIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAM 144
Cdd:COG1484   68 AKTLEDFDFDAqpgldRRQILELATLD-FIER-GENL---ILLGPPGTGKTHLAIALGHEACRAGYRVRFTTAPDLVNEL 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 145 KDTFGNRetSEEQLLSDLSKVDLLVIDEIGMQTESRYEKVIINQIVDRRsSSKRPTgMLTnSN--MEEMNKLLGERVM-- 220
Cdd:COG1484  143 KEARADG--RLERLLKRLAKVDLLILDELGYLPLDAEGAELLFELISDR-YERRST-IIT-SNlpFSEWGEVFGDPTLat 217

                        250       260
                 ....*....|....*....|....
gi 636385644 221 ---DRMrLGNSLWVIFNWESYRHR 241
Cdd:COG1484  218 ailDRL-VHHAHIIELKGESYRLK 240
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 73-222 7.43e-20

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 86.49  E-value: 7.43e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  73 FDNYRVECEGQ-----M-NALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKD 146
Cdd:PRK06835 149 YSDEKDDDEPLsprknMeKILEKCKNFIENFDKNNENLLFYGNTGTGKTFLSNCIAKELLDRGKSVIYRTADELIEILRE 228

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 636385644 147 TFGNRETSEEQLLSDLSKVDLLVIDEIGmqTESRYE--KVIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGERVMDR 222
Cdd:PRK06835 229 IRFNNDKELEEVYDLLINCDLLIIDDLG--TEKITEfsKSELFNLINKRLLRQKKMIISTNLSLEELLKTYSERISSR 304
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 41-239 1.52e-18

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 81.36  E-value: 1.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  41 LRSEALERENRAMKM--------------------QRTFNRSGIRPLHQnCSFdnyrvecegqmnaLARARqyveefdgN 100
Cdd:NF038214  35 LEAELAERENRRIERrlkrarfpaaktledfdftaAPGLDKAQIRELAT-LDF-------------IERAE--------N 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 101 IasfIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDtfGNRETSEEQLLSDLSKVDLLVIDEIGMQTESR 180
Cdd:NF038214  93 V---LLLGPPGTGKTHLAIALGYAACRQGYRVRFTTAADLVEQLAQ--ARADGRLGRLLRRLARYDLLIIDELGYLPFSR 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 636385644 181 YEKVIINQIVDRRsSSKRPTgMLTnSNM--EEMNKLLGERVM-----DRMrLGNSLWVIFNWESYR 239
Cdd:NF038214 168 EGANLLFELIADR-YERGST-IIT-SNLpfSEWGEVFGDPTLaaailDRL-VHHAHILELKGESYR 229
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
 97-241 1.12e-14

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 70.94  E-value: 1.12e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   97 FDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKdtFGNRETSEEQLLSDLSKVDLLVIDEIGMQ 176
Cdd:pfam01695  88 FIDRAQNVVLLGPPGVGKTHLAIALGVEACRAGYSVRFTSAADLVNQLK--RAHGDGKLTRKLQQLLKPDVLILDEWGYL 165

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  177 TESRYEKVIINQIVDRRsSSKRPTGMLTNSNMEEMNKLLGERVM-----DRMrLGNSLWVIFNWESYRHR 241
Cdd:pfam01695 166 PLDQAEANLLFQVISKR-YEHRSIILTSNLPFGEWGQVFGDAVLatailDRL-LHHCHIVPIKGESYRLK 233
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 82-174 1.34e-13

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 66.40  E-value: 1.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  82 GQMNALARARQYVEEFDGNiaSFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKD--TFGNRETSEEQLL 159
Cdd:cd00009    2 GQEEAIEALREALELPPPK--NLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVaeLFGHFLVRLLFEL 79

                         90
                 ....*....|....*
gi 636385644 160 SDLSKVDLLVIDEIG 174
Cdd:cd00009   80 AEKAKPGVLFIDEID 94
PRK08181 PRK08181
transposase; Validated
 44-241 3.08e-11

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 61.87  E-value: 3.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  44 EALERENRamKMQRTFNRSGIRPLHQNCSFDNYRVE--CEGQMNALARARQYVeefdGNIASFIFSGKPGTGKNHLAAAI 121
Cdd:PRK08181  53 ELAERARR--RIERHLAEAHLPPGKTLDSFDFEAVPmvSKAQVMAIAAGDSWL----AKGANLLLFGPPGGGKSHLAAAI 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 122 CNELLLRGKSVLIITVADIMSAMKdtFGNRETSEEQLLSDLSKVDLLVIDEIGMQTESRYEKVIINQIVDRRssSKRPTG 201
Cdd:PRK08181 127 GLALIENGWRVLFTRTTDLVQKLQ--VARRELQLESAIAKLDKFDLLILDDLAYVTKDQAETSVLFELISAR--YERRSI 202

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 636385644 202 MLT-NSNMEEMNKLLGERVM-----DRMrLGNSLWVIFNWESYRHR 241
Cdd:PRK08181 203 LITaNQPFGEWNRVFPDPAMtlaavDRL-VHHATIFEMNVESYRRR 247
PRK06921 PRK06921
hypothetical protein; Provisional
 54-244 1.20e-10

hypothetical protein; Provisional


Pssm-ID: 180750 [Multi-domain]  Cd Length: 266  Bit Score: 60.18  E-value: 1.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  54 KMQRTFNRSGIRPLHQNCSFDNYRVECEGQM--NALARARQYVEEFDgNIA-----SFIFSGKPGTGKNHLAAAICNELL 126
Cdd:PRK06921  64 KIERLLKASEITEAFRKLTFKNFKTEGKPQAikDAYECAVEYVKDFE-KIQesrknSIALLGQPGSGKTHLLTAAANELM 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 127 LR-GKSVLIITVADIMSAMKDTFGNRETSeeqlLSDLSKVDLLVIDEI-----GMQTESRYEKVIINQIVDRRSSSKRPT 200
Cdd:PRK06921 143 RKkGVPVLYFPFVEGFGDLKDDFDLLEAK----LNRMKKVEVLFIDDLfkpvnGKPRATEWQIEQMYSVLNYRYLNHKPI 218

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 636385644 201 GMLTNSNMEEMNKL---LGERVMDRmrlGNSLWVIFNWESY--RHRVTG 244
Cdd:PRK06921 219 LISSELTIDELLDIdeaLGSRIVEM---CKDYLVIIKGDSFelNHRLEG 264
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
 70-224 8.85e-10

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 57.57  E-value: 8.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  70 NCSFDNYRVECEGQMNALARARQYVEEF--DGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDT 147
Cdd:PRK08939 123 QASLADIDLDDRDRLDALMAALDFLEAYppGEKVKGLYLYGDFGVGKSYLLAAIANELAKKGVSSTLLHFPEFIRELKNS 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 148 FGNRETSEEqlLSDLSKVDLLVIDEIGMQTES---RYEkvIINQIVDRRSSSKRPTGMLTNSNMEEMNKLLGE------- 217
Cdd:PRK08939 203 ISDGSVKEK--IDAVKEAPVLMLDDIGAEQMSswvRDE--VLGVILQYRMQEELPTFFTSNFDFDELEHHLAYtqrgede 278

                        170
                 ....*....|..
gi 636385644 218 -----RVMDRMR 224
Cdd:PRK08939 279 twkaaRIMERIR 290
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
67-173 1.24e-09

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 57.12  E-value: 1.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  67 LHQNCSFDNYRVeceGQMNALARA--RQyVEEFDGNIASFIF-SGKPGTGKNHLAAAICNELLLR--GKSVLIITVADIM 141
Cdd:COG0593    1 LNPRYTFDNFVV---GPSNRLAHAaaLA-VAEWPGKAYNPLFlYGGVGLGKTHLLHAIGNEALENnpGARVVYLTAEEFT 76

                         90       100       110
                 ....*....|....*....|....*....|..
gi 636385644 142 SAMKDTFGNRETseEQLLSDLSKVDLLVIDEI 173
Cdd:COG0593   77 NDFINAIRNNTI--EEFKEKYRSVDVLLIDDI 106
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 105-229 7.40e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.15  E-value: 7.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   105 IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEQLLSD-------------LSKVDLLVID 171
Cdd:smart00382   6 LIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSgelrlrlalalarKLKPDVLILD 85

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 636385644   172 EIGMQTESRYEKVIINQIVDRRSSSKRPTG-----MLTNSNMEEMNKLLGERVMDRMRLGNSL 229
Cdd:smart00382  86 EITSLLDAEQEALLLLLEELRLLLLLKSEKnltviLTTNDEKDLGPALLRRRFDRRIVLLLIL 148
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 13-173 4.98e-08

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 52.92  E-value: 4.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   13 LQKMMPAHIEPAFKTGEEllawqKEQGRLRSEALERENRamkmQRTFNRSGIRPLHQNCSFDNYrVECEGQMNALARARQ 92
Cdd:TIGR00362  59 LQELFGAEIEIEFTVGED-----EEELEPNSKKPEPAPP----EAPAPPSSASGLNPKYTFDNF-VVGKSNRLAHAAALA 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   93 yVEEFDGNIAS--FIFsGKPGTGKNHLAAAICNELLLR--GKSVLIIT----VADIMSAMKdtfgNRETseEQLLSDLSK 164
Cdd:TIGR00362 129 -VAENPGKAYNplFIY-GGVGLGKTHLLHAIGNEILENnpNAKVLYVSsekfTNDFVNALR----NNKM--EEFKEKYRS 200


                  ....*....
gi 636385644  165 VDLLVIDEI 173
Cdd:TIGR00362 201 VDLLLIDDI 209
DEXXQc_SF1 cd18043
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ...
 103-186 1.74e-05

DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350801 [Multi-domain]  Cd Length: 127  Bit Score: 42.96  E-value: 1.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 103 SFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVAD-----------IMSAMKDTfgnretseEQLLSDLSKVDLLVID 171
Cdd:cd18043   16 NVVIQGPPGTGKSQTIANIIANALARGKRVLFVSEKKaaldvvrfpcwIMSPLSVS--------QYLPLNRNLFDLVIFD 87

                         90       100
                 ....*....|....*....|..
gi 636385644 172 EIG-MQTES------RYEKVII 186
Cdd:cd18043   88 EASqIPIEEalpalfRGKQVVV 109
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
 82-175 2.52e-05

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 43.31  E-value: 2.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  82 GQMNALARArqyveeFDGNIasFIFSGKPGTGKNHLAAAICNELLLRGKSVLI-------------ITVAD---IMSAMK 145
Cdd:cd17933    1 EQKAAVRLV------LRNRV--SVLTGGAGTGKTTTLKALLAALEAEGKRVVLaaptgkaakrlseSTGIEastIHRLLG 72

                         90       100       110
                 ....*....|....*....|....*....|
gi 636385644 146 DTFGnrETSEEQLLSDLSKVDLLVIDEIGM 175
Cdd:cd17933   73 INPG--GGGFYYNEENPLDADLLIVDEASM 100
DEXSc_Pif1_like cd18037
DEAD-box helicase domain of Pif1; Pif1 and other members of this family are RecD-like ...
 106-175 2.61e-04

DEAD-box helicase domain of Pif1; Pif1 and other members of this family are RecD-like helicases involved in maintaining genome stability through unwinding double-stranded DNAs (dsDNAs), DNA/RNA hybrids, and G quadruplex (G4) structures. The members of Pif1 helicase subfamily studied so far all appear to contribute to telomere maintenance. Pif1 is a member of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350795 [Multi-domain]  Cd Length: 183  Bit Score: 40.70  E-value: 2.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 106 FSGKPGTGKNHLAAAICNELLLRGKSVlIIT----VA---------------DIMSAMKDTFGNRETSEEQLLSDLSKVD 166
Cdd:cd18037   17 FTGSAGTGKSYLLRRIIRALPSRPKRV-AVTastgIAacniggttlhsfagiGLGSEPAEDLLERVKRSPYLVQRWRKCD 95


                 ....*....
gi 636385644 167 LLVIDEIGM 175
Cdd:cd18037   96 VLIIDEISM 104
PRK06526 PRK06526
transposase; Provisional
 105-174 3.98e-04

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 40.62  E-value: 3.98e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 105 IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFGNRETSEEqlLSDLSKVDLLVIDEIG 174
Cdd:PRK06526 102 VFLGPPGTGKTHLAIGLGIRACQAGHRVLFATAAQWVARLAAAHHAGRLQAE--LVKLGRYPLLIVDEVG 169
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 105-190 7.13e-04

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 40.28  E-value: 7.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 105 IFSGKPGTGKNHLAAAICNELllrGKSVLIITVADIMS--------AMKDTFgnretseeQLLSDLSKVdLLVIDEI--- 173
Cdd:COG0464  195 LLYGPPGTGKTLLARALAGEL---GLPLIEVDLSDLVSkyvgetekNLREVF--------DKARGLAPC-VLFIDEAdal 262

                         90       100
                 ....*....|....*....|
gi 636385644 174 ---GMQTESRYEKVIINQIV 190
Cdd:COG0464  263 agkRGEVGDGVGRRVVNTLL 282
PRK09183 PRK09183
transposase/IS protein; Provisional
 105-193 7.30e-04

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 39.69  E-value: 7.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 105 IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMkDTFGNRETSEEQLLSDLSKVDLLVIDEIGMQTESRYEKV 184
Cdd:PRK09183 106 VLLGPSGVGKTHLAIALGYEAVRAGIKVRFTTAADLLLQL-STAQRQGRYKTTLQRGVMAPRLLIIDEIGYLPFSQEEAN 184


                 ....*....
gi 636385644 185 IINQIVDRR 193
Cdd:PRK09183 185 LFFQVIAKR 193
Bac_DnaA pfam00308
Bacterial dnaA protein;
67-173 7.75e-04

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 39.62  E-value: 7.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644   67 LHQNCSFDNYrVECEGQMNALARARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELL--LRGKSVLIITVADIMSAM 144
Cdd:pfam00308   1 LNPRYTFENF-VIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALqnAPNLRVVYLTAEEFLNDF 79

                          90       100
                  ....*....|....*....|....*....
gi 636385644  145 KDTFGNRETseEQLLSDLSKVDLLVIDEI 173
Cdd:pfam00308  80 VDAIRDNKT--NQFKEKYRNVDVLLIDDI 106
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 105-173 8.78e-04

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 38.34  E-value: 8.78e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636385644  105 IFSGKPGTGKNHLAAAICNELllrGKSVLIITVADIMSAMkdtFGNRETSEEQLLSDLSKV--DLLVIDEI 173
Cdd:pfam00004   2 LLYGPPGTGKTTLAKAVAKEL---GAPFIEISGSELVSKY---VGESEKRLRELFEAAKKLapCVIFIDEI 66
44 PHA02544
clamp loader, small subunit; Provisional
 91-172 1.09e-03

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 39.59  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  91 RQYVEefDGNIASFIF-SGKPGTGKNHLAAAICNELllrGKSVLIITVADimsAMKDTFGNRETSEEQLLSDLSKVDLLV 169
Cdd:PHA02544  34 KSIVK--KGRIPNMLLhSPSPGTGKTTVAKALCNEV---GAEVLFVNGSD---CRIDFVRNRLTRFASTVSLTGGGKVII 105


                 ...
gi 636385644 170 IDE 172
Cdd:PHA02544 106 IDE 108
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 105-173 2.12e-03

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 37.66  E-value: 2.12e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636385644 105 IFSGKPGTGKNHLAAAICNELllrGKSVLIITVADIMSAMkdtFGNRETSEEQLLSDLSKV--DLLVIDEI 173
Cdd:cd19503   38 LLHGPPGTGKTLLARAVANEA---GANFLSISGPSIVSKY---LGESEKNLREIFEEARSHapSIIFIDEI 102
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 103-190 2.47e-03

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 37.65  E-value: 2.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644 103 SFIFSGKPGTGKNHLAAAICNELllrGKSVLIITVADIMS--------AMKDTFgnretseeQLLSDLSKVdLLVIDEI- 173
Cdd:cd19481   28 GILLYGPPGTGKTLLAKALAGEL---GLPLIVVKLSSLLSkyvgesekNLRKIF--------ERARRLAPC-ILFIDEId 95

                         90       100
                 ....*....|....*....|...
gi 636385644 174 ------GMQTESRYEKVIINQIV 190
Cdd:cd19481   96 aigrkrDSSGESGELRRVLNQLL 118
rfc PRK00440
replication factor C small subunit; Reviewed
 82-126 3.52e-03

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 37.93  E-value: 3.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 636385644  82 GQMNALARARQYVEEfdGNIASFIFSGKPGTGKNHLAAAICNELL 126
Cdd:PRK00440  21 GQEEIVERLKSYVKE--KNMPHLLFAGPPGTGKTTAALALARELY 63
PLN03025 PLN03025
replication factor C subunit; Provisional
 82-126 4.05e-03

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 37.79  E-value: 4.05e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 636385644  82 GQMNALARARQYVEefDGNIASFIFSGKPGTGKNHLAAAICNELL 126
Cdd:PLN03025  17 GNEDAVSRLQVIAR--DGNMPNLILSGPPGTGKTTSILALAHELL 59
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 99-173 4.06e-03

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 37.76  E-value: 4.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 636385644  99 GNIASFIFSGKPGTGKNHLAAAICNELllrGKSVLII-----TVADIMSAMKDTFGNRETSEEqllsdlskvDLLVIDEI 173
Cdd:PRK13342  34 GRLSSMILWGPPGTGKTTLARIIAGAT---DAPFEALsavtsGVKDLREVIEEARQRRSAGRR---------TILFIDEI 101
SIMIBI cd01983
SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal ...
 104-170 4.17e-03

SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal recognition particle, MinD, and BioD), consists of signal recognition particle (SRP) GTPases, the assemblage of MinD-like ATPases, which are involved in protein localization, chromosome partitioning, and membrane transport, and a group of metabolic enzymes with kinase or related phosphate transferase activity. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.


Pssm-ID: 349751 [Multi-domain]  Cd Length: 107  Bit Score: 35.87  E-value: 4.17e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 636385644 104 FIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADI----MSAMKDTFGNRETSEEQLLSdlSKVDLLVI 170
Cdd:cd01983    4 AVTGGKGGVGKTTLAAALAVALAAKGYKVLLIDLDDYvlidGGGGLETGLLLGTIVALLAL--KKADEVIV 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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