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Conserved domains on  [gi|630601724|gb|KCZ01797|]
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enoyl-CoA hydratase/isomerase family protein [Acinetobacter baumannii 25691_8]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 23-339 4.87e-109

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 322.50  E-value: 4.87e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   23 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALD 102
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  103 LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGLFTGLTGSIMTA 180
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLS-RlpGELGLYLALTGARLNG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  181 AGAYSIGWATHICE-AQRDNVLQKVLNINWahypaGDFRAIDDTLNSLHR--PVAAGPLQNSLDVIHSVCRGSSFEQDYQ 257
Cdd:pfam16113 161 ADALAAGLATHYVPsARLPALEEALAALDW-----SDPADVDAVLAEFAEesDPPPSPLAAHREAIDRCFSADTVEEIIA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  258 AIVSLRDAsSDWLRQASENLQKGSPSTAAITWLLWQWGKQVhSWDEVFDLEAQISEWKIRHPDFVEGVRARLVDKDLSPE 337
Cdd:pfam16113 236 ALEAEADG-DEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL-SLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPK 313


                  ..
gi 630601724  338 WK 339
Cdd:pfam16113 314 WS 315
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 23-339 4.87e-109

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 322.50  E-value: 4.87e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   23 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALD 102
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  103 LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGLFTGLTGSIMTA 180
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLS-RlpGELGLYLALTGARLNG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  181 AGAYSIGWATHICE-AQRDNVLQKVLNINWahypaGDFRAIDDTLNSLHR--PVAAGPLQNSLDVIHSVCRGSSFEQDYQ 257
Cdd:pfam16113 161 ADALAAGLATHYVPsARLPALEEALAALDW-----SDPADVDAVLAEFAEesDPPPSPLAAHREAIDRCFSADTVEEIIA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  258 AIVSLRDAsSDWLRQASENLQKGSPSTAAITWLLWQWGKQVhSWDEVFDLEAQISEWKIRHPDFVEGVRARLVDKDLSPE 337
Cdd:pfam16113 236 ALEAEADG-DEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL-SLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPK 313


                  ..
gi 630601724  338 WK 339
Cdd:pfam16113 314 WS 315
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 12-339 7.96e-79

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 245.50  E-value: 7.96e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA 91
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPLAA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGL 169
Cdd:PRK05617  83 DRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLS-RapGALGT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 170 FTGLTGSIMTAAGAYSIGWATH-ICEAQRDNVLQKVLNINWAHYPAGdfraIDDTLNSLHRPVAAGPLQNSLDVIHSVCR 248
Cdd:PRK05617 162 YLALTGARISAADALYAGLADHfVPSADLPALLDALISLRWDSGADV----VDAALAAFATPAPASELAAQRAWIDECFA 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 249 GSSFEqdyqAIV-SLRDASSDWLRQASENLQKGSPSTAAITWllwqwgKQVH-----SWDEVFDLEAQISEWKIRHPDFV 322
Cdd:PRK05617 238 GDTVE----DIIaALEADGGEFAAKTADTLRSRSPTSLKVTL------EQLRrarglTLEECLRRELRLALAMLRSPDFV 307

                        330
                 ....*....|....*..
gi 630601724 323 EGVRARLVDKDLSPEWK 339
Cdd:PRK05617 308 EGVRAVLIDKDRNPKWS 324
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 14-207 3.42e-45

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 153.87  E-value: 3.42e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDVRKLRQLviNQEVETANK 93
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAAL--SDAGEEARA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  94 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGLFT 171
Cdd:cd06558   78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLvgPARAREL 157

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 630601724 172 GLTGSIMTAAGAYSIGWATHICEAqrDNVLQKVLNI 207
Cdd:cd06558  158 LLTGRRISAEEALELGLVDEVVPD--EELLAAALEL 191
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 17-195 8.56e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 128.36  E-value: 8.56e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  17 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDvrkLRQLVINQEVETANKFFQ 96
Cdd:COG1024    4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGAD---LKELAAAADPEEARAFAR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  97 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIG------LF 170
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRL--VGlarakeLL 157

                        170       180
                 ....*....|....*....|....*
gi 630601724 171 tgLTGSIMTAAGAYSIGWATHICEA 195
Cdd:COG1024  158 --LTGRRIDAEEALELGLVNRVVPD 180
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 17-161 2.85e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 67.94  E-value: 2.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   17 EAKNGWRIVRLNRPKS-LHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFF 95
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 630601724   96 QQEYAldlLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSR--LAMPEINIGLYPDVGASRFL 161
Cdd:TIGR02441  98 QEMFE---RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRL 162
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 23-339 4.87e-109

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 322.50  E-value: 4.87e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   23 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALD 102
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRLN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  103 LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGLFTGLTGSIMTA 180
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLS-RlpGELGLYLALTGARLNG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  181 AGAYSIGWATHICE-AQRDNVLQKVLNINWahypaGDFRAIDDTLNSLHR--PVAAGPLQNSLDVIHSVCRGSSFEQDYQ 257
Cdd:pfam16113 161 ADALAAGLATHYVPsARLPALEEALAALDW-----SDPADVDAVLAEFAEesDPPPSPLAAHREAIDRCFSADTVEEIIA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  258 AIVSLRDAsSDWLRQASENLQKGSPSTAAITWLLWQWGKQVhSWDEVFDLEAQISEWKIRHPDFVEGVRARLVDKDLSPE 337
Cdd:pfam16113 236 ALEAEADG-DEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL-SLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPK 313


                  ..
gi 630601724  338 WK 339
Cdd:pfam16113 314 WS 315
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 12-339 7.96e-79

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 245.50  E-value: 7.96e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA 91
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPLAA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGL 169
Cdd:PRK05617  83 DRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLS-RapGALGT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 170 FTGLTGSIMTAAGAYSIGWATH-ICEAQRDNVLQKVLNINWAHYPAGdfraIDDTLNSLHRPVAAGPLQNSLDVIHSVCR 248
Cdd:PRK05617 162 YLALTGARISAADALYAGLADHfVPSADLPALLDALISLRWDSGADV----VDAALAAFATPAPASELAAQRAWIDECFA 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 249 GSSFEqdyqAIV-SLRDASSDWLRQASENLQKGSPSTAAITWllwqwgKQVH-----SWDEVFDLEAQISEWKIRHPDFV 322
Cdd:PRK05617 238 GDTVE----DIIaALEADGGEFAAKTADTLRSRSPTSLKVTL------EQLRrarglTLEECLRRELRLALAMLRSPDFV 307

                        330
                 ....*....|....*..
gi 630601724 323 EGVRARLVDKDLSPEWK 339
Cdd:PRK05617 308 EGVRAVLIDKDRNPKWS 324
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 14-207 3.42e-45

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 153.87  E-value: 3.42e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDVRKLRQLviNQEVETANK 93
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAAL--SDAGEEARA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  94 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGLFT 171
Cdd:cd06558   78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLvgPARAREL 157

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 630601724 172 GLTGSIMTAAGAYSIGWATHICEAqrDNVLQKVLNI 207
Cdd:cd06558  158 LLTGRRISAEEALELGLVDEVVPD--EELLAAALEL 191
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 12-338 1.48e-42

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 153.21  E-value: 1.48e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETA 91
Cdd:PLN02851  42 DQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADVVSLYHLINEGNVEEC 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLF 170
Cdd:PLN02851 121 KLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRlPGYLGEY 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 171 TGLTGSIMTAAGAYSIGWATHICEAQRDNVLQK-----------VLNINWAHYpaGDFRAIDDTlNSLHRpvaagplqns 239
Cdd:PLN02851 201 LALTGQKLNGVEMIACGLATHYCLNARLPLIEErlgklltddpaVIEDSLAQY--GDLVYPDKS-SVLHK---------- 267

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 240 LDVIHSVCRGSSFEQDYQAIVSLRDASSD-WLRQASENLQKGSPSTAAITWLLWQWGKqVHSWDEVFDLEAQIS---EWK 315
Cdd:PLN02851 268 IETIDKCFGHDTVEEIIEALENEAASSYDeWCKKALKKIKEASPLSLKVTLQSIREGR-FQTLDQCLAREYRISlcgVSK 346

                        330       340
                 ....*....|....*....|...
gi 630601724 316 IRHPDFVEGVRARLVDKDLSPEW 338
Cdd:PLN02851 347 WVSGDFCEGVRARLVDKDFAPKW 369
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 14-339 3.14e-41

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 149.10  E-value: 3.14e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANK 93
Cdd:PLN02988  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDIEQGNWRLGAN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  94 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLFTG 172
Cdd:PLN02988  90 FFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRlPGFFGEYVG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 173 LTGSIMTAAGAYSIGWATHICEAQRDNVLQKVLNINWAHYPAgdFRAIDDTLNSLHRPVAAGPLQNSLDVIHSVCRGSSF 252
Cdd:PLN02988 170 LTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPT--FASTILDAYTQHPRLKPQSAYHRLDVIDRCFSRRTV 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 253 EQDYQAIVslRDASSD---WLRQASENLQKGSPSTAAITWLLWQWGK-------QVHSWDEVFD-LEAQISEwkirhpDF 321
Cdd:PLN02988 248 EEIISALE--REATQEadgWISATIQALKKASPASLKISLRSIREGRlqgvgqcLIREYRMVCHvMKGEISK------DF 319

                        330
                 ....*....|....*...
gi 630601724 322 VEGVRARLVDKDLSPEWK 339
Cdd:PLN02988 320 VEGCRAILVDKDKNPKWE 337
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 14-345 8.27e-41

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 147.64  E-value: 8.27e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANK 93
Cdd:PLN02874  13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGRESDDSCLEVV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  94 FfqQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLFTG 172
Cdd:PLN02874  92 Y--RMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRlPGHLGEYLA 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 173 LTGSIMTAAGAYSIGWATHICEAQRDNVLQK-VLNINwahypAGDFRAIDDTLNSLHRPVAAGP--LQNSLDVIHSVCRG 249
Cdd:PLN02874 170 LTGARLNGKEMVACGLATHFVPSEKLPELEKrLLNLN-----SGDESAVQEAIEEFSKDVQADEdsILNKQSWINECFSK 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 250 SSFEQDYQAIVS-LRDASSDWLRQASENLQKGSPSTAAITWLLWQWGKQvHSWDEVFDLEAQISEWKIR---HPDFVEGV 325
Cdd:PLN02874 245 DTVEEIIKAFESeASKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRK-QSLAECLKKEFRLTMNILRstvSDDVYEGI 323

                        330       340
                 ....*....|....*....|..
gi 630601724 326 RARLVDKDLSPEW--KACEDLT 345
Cdd:PLN02874 324 RALVIDKDNAPKWnpSTLDEVT 345
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 17-195 8.56e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 128.36  E-value: 8.56e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  17 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDvrkLRQLVINQEVETANKFFQ 96
Cdd:COG1024    4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGAD---LKELAAAADPEEARAFAR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  97 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIG------LF 170
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRL--VGlarakeLL 157

                        170       180
                 ....*....|....*....|....*
gi 630601724 171 tgLTGSIMTAAGAYSIGWATHICEA 195
Cdd:COG1024  158 --LTGRRIDAEEALELGLVNRVVPD 180
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 14-344 7.07e-32

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 124.03  E-value: 7.07e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANK 93
Cdd:PLN02157  39 VLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSLYHLRKRGSPDAIRE 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  94 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLFTG 172
Cdd:PLN02157 118 FFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHlPGRLGEYLG 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 173 LTGSIMTAAGAYSIGWATHICEAQRDNVLQKVLNINWAHYPAGDFRAIDDTLNSLHrPVAAGPLQNsLDVIHSVCRGSSF 252
Cdd:PLN02157 198 LTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESCLEKCAEVAH-PEKTGVIRR-IDLLEKCFSHDTV 275

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 253 EQ--DYQAIVSLRDASSdWLRQASENLQKGSPSTAAITWLLWQWGKqVHSWDEVFDLEAQISEWKIRHP---DFVEGVRA 327
Cdd:PLN02157 276 EEiiDSLEIEAGRRKDT-WCITTLRRLKESSPLSLKVALRSIREGR-LQTLDQCLIREYRMSLQGLIGPmsgNFCEGVRA 353

                        330       340
                 ....*....|....*....|...
gi 630601724 328 RLVDKDLSPEW------KACEDL 344
Cdd:PLN02157 354 RLIDKDEAPKWdppsleKVSEDM 376
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 17-164 3.71e-23

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 97.05  E-value: 3.71e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   17 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDVRKLRQLVINQEVETANKFfq 96
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYRENV-- 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 630601724   97 qeYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR 164
Cdd:pfam00378  78 --LDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRI 143
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 10-236 6.57e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 85.30  E-value: 6.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  10 HPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQL--VINQE 87
Cdd:PRK06688   3 MVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVL-TGAGRAFSAGGDIKDFPKAppKPPDE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  88 VETANKFFQQeyaldllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdrgQI 167
Cdd:PRK06688  82 LAPVNRFLRA-------IAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLP---RL 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 630601724 168 glfTG--------LTGSIMTAAGAYSIGWATHIceaqrdnvlqkvlninwahYPAGDFRAIDDtlnSLHRPVAAGPL 236
Cdd:PRK06688 152 ---IGraraaemlLLGEPLSAEEALRIGLVNRV-------------------VPAAELDAEAD---AQAAKLAAGPA 203
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
12-194 4.80e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 83.01  E-value: 4.80e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLrqlvinqevetA 91
Cdd:PRK07509   3 DRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVIL-SGEGGAFCAGLDVKSV-----------A 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKFFQQEYALDLLLH---NYAK-----------PVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGA 157
Cdd:PRK07509  71 SSPGNAVKLLFKRLPgnaNLAQrvslgwrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAG 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 630601724 158 SRFLadRGQIG-----LFTgLTGSIMTAAGAYSIGWATHICE 194
Cdd:PRK07509 151 TVSL--RGLVRkdvarELT-YTARVFSAEEALELGLVTHVSD 189
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
14-194 8.45e-18

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 82.10  E-value: 8.45e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA-- 91
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGll 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 -NKFFQQeyaldllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQIGLF 170
Cdd:PRK05809  86 gNKVFRK-------LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKA 158

                        170       180
                 ....*....|....*....|....*.
gi 630601724 171 TGL--TGSIMTAAGAYSIGWATHICE 194
Cdd:PRK05809 159 KELiyTGDMINAEEALRIGLVNKVVE 184
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
12-192 1.66e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 81.34  E-value: 1.66e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA 91
Cdd:PRK05980   3 DTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVAL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFL---ADRGQiG 168
Cdd:PRK05980  83 RDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLprlAGRKR-A 161

                        170       180
                 ....*....|....*....|....
gi 630601724 169 LFTGLTGSIMTAAGAYSIGWATHI 192
Cdd:PRK05980 162 LELLLTGDAFSAERALEIGLVNAV 185
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 11-207 5.07e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 80.10  E-value: 5.07e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  11 PDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRklrqlvinqEVET 90
Cdd:PRK08138   7 DVVLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIK---------EFAT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  91 ANkffqqeyALDLLL---HNY-------AKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRF 160
Cdd:PRK08138  77 AG-------AIEMYLrhtERYweaiaqcPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQR 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 630601724 161 LAdRGqIGLFTG----LTGSIMTAAGAYSIGWATHICEaqRDNVLQKVLNI 207
Cdd:PRK08138 150 LV-RA-VGKFKAmrmaLTGCMVPAPEALAIGLVSEVVE--DEQTLPRALEL 196
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 8-195 6.75e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 79.75  E-value: 6.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   8 SYHPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQE 87
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  88 VETAnkFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgQI 167
Cdd:PRK06127  87 AVAA--YEQAVEAAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVD--LV 162

                        170       180       190
                 ....*....|....*....|....*....|....
gi 630601724 168 G------LFtgLTGSIMTAAGAYSIGWATHICEA 195
Cdd:PRK06127 163 GpsaakdLF--YTARRFDAAEALRIGLVHRVTAA 194
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 13-196 6.73e-15

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 73.65  E-value: 6.73e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  13 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVInqeVETAN 92
Cdd:PRK09674   3 ELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVI-TGNARFFAAGADLNEMAEKDL---AATLN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  93 KFFQQEYALdllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS-RFLADRGQ-IGLF 170
Cdd:PRK09674  79 DPRPQLWQR---LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTqRLIRSVGKsLASQ 155

                        170       180
                 ....*....|....*....|....*.
gi 630601724 171 TGLTGSIMTAAGAYSIGWATHICEAQ 196
Cdd:PRK09674 156 MVLTGESITAQQAQQAGLVSEVFPPE 181
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 15-207 1.60e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 72.84  E-value: 1.60e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  15 VEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVR---KLRQLVINQEV--- 88
Cdd:PRK07657   7 VDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKeraGMNEEQVRHAVsli 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  89 -ETANKFFQqeyaldlllhnYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQI 167
Cdd:PRK07657  87 rTTMEMVEQ-----------LPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGV 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 630601724 168 GLFTGL--TGSIMTAAGAYSIGWATHICEaqRDNVLQKVLNI 207
Cdd:PRK07657 156 GRAKELiyTGRRISAQEAKEIGLVEFVVP--AHLLEEKAIEI 195
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 24-194 2.10e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 69.30  E-value: 2.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  24 IVRLNRPKSLHALDESIVTALLRVFEDF-RDDEQVKAIwLDSTTPKAFCAGGDvrkLRQLVINQEVETANKFF---QQEY 99
Cdd:PRK06494  16 IVTLNRPEVMNALHLDAHFELEEVFDDFaADPEQWVAI-VTGAGDKAFSAGND---LKEQAAGGKRGWPESGFgglTSRF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 100 ALDlllhnyaKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgQIGLFTG----LTG 175
Cdd:PRK06494  92 DLD-------KPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPR--QIGLKRAmgmiLTG 162

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 630601724 176 SIMTAAGAYSIG-----------------WATHICE 194
Cdd:PRK06494 163 RRVTAREGLELGfvnevvpagellaaaerWADDILA 198
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 8-183 2.44e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 66.22  E-value: 2.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   8 SYHPDLVVEEAKNGwrIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRklrqlvinqe 87
Cdd:PRK05862   2 AYETILVETRGRVG--LITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIK---------- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  88 vETANKFFQQEYALDLL-----LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS---- 158
Cdd:PRK05862  69 -EMADLSFMDVYKGDYItnwekVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSqrlt 147

                        170       180
                 ....*....|....*....|....*
gi 630601724 159 RFLADRGQIGLFtgLTGSIMTAAGA 183
Cdd:PRK05862 148 RAVGKAKAMDLC--LTGRMMDAAEA 170
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 17-161 2.85e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 67.94  E-value: 2.85e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   17 EAKNGWRIVRLNRPKS-LHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFF 95
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 630601724   96 QQEYAldlLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSR--LAMPEINIGLYPDVGASRFL 161
Cdd:TIGR02441  98 QEMFE---RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRL 162
PLN02600 PLN02600
enoyl-CoA hydratase
 25-172 7.59e-12

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 64.83  E-value: 7.59e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVrKLRQLVINQEVEtanKFFQQEYALDLL 104
Cdd:PLN02600   8 LRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADL-KERRKMSPSEVQ---KFVNSLRSTFSS 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 630601724 105 LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA-----DRGQIGLFTG 172
Cdd:PLN02600  84 LEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPrlvgrSRAKELIFTG 156
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
25-197 2.67e-11

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 63.17  E-value: 2.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSlHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDvrkLRQLVINQEVETANKF-----FQQEY 99
Cdd:PRK03580  16 ITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWD---LKAAAEGEAPDADFGPggfagLTEIF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 100 ALDlllhnyaKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGLFTGLTGSI 177
Cdd:PRK03580  92 DLD-------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRlpPAIANEMVMTGRR 164

                        170       180
                 ....*....|....*....|
gi 630601724 178 MTAAGAYSIGWATHICEAQR 197
Cdd:PRK03580 165 MDAEEALRWGIVNRVVPQAE 184
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 25-196 2.92e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 63.02  E-value: 2.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVEtaNKFFQQEYAlDLL 104
Cdd:PRK05995  17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMAGYSDDE--NRADARRLA-DML 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 105 --LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS---RFLADRGQIGLFtgLTGSIMT 179
Cdd:PRK05995  93 raIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPyviRAMGERAARRYF--LTAERFD 170

                        170
                 ....*....|....*..
gi 630601724 180 AAGAYSIGWATHICEAQ 196
Cdd:PRK05995 171 AAEALRLGLVHEVVPAE 187
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 23-162 3.81e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 62.71  E-value: 3.81e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  23 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDvrkLRQLVINQEVETAnkffQQEYALD 102
Cdd:PRK07511  14 LVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGN---LNRLLENRAKPPS----VQAASID 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 630601724 103 LL------LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA 162
Cdd:PRK07511  86 GLhdwiraIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLA 151
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 11-195 3.84e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 62.70  E-value: 3.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  11 PDLVVEEAKNGWRIVrLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLvinqevET 90
Cdd:PRK06144   8 DELLLEVRGGIARIT-FNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAF------ST 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  91 ANKFFQQEYALDLLLH---NYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPeI-----------NIG-LYPDV 155
Cdd:PRK06144  81 AEDAVAYERRIDRVLGaleQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP-IartlgnclsmsNLArLVALL 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 630601724 156 GASRFladRGQIglftgLTGSIMTAAGAYSIGWATHICEA 195
Cdd:PRK06144 160 GAARV---KDML-----FTARLLEAEEALAAGLVNEVVED 191
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 12-194 5.08e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 62.44  E-value: 5.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQlvinQEVETA 91
Cdd:PRK05870   3 DPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADLTALGA----APGRPA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGL 169
Cdd:PRK05870  78 EDGLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAvgPQVAR 157

                        170       180
                 ....*....|....*....|....*
gi 630601724 170 FTGLTGSIMTAAGAYSIGWATHICE 194
Cdd:PRK05870 158 AALLFGMRFDAEAAVRHGLALMVAD 182
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 24-207 1.17e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 61.19  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  24 IVRLNRPKSlHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLvinQEVETANKFFQQEYALDL 103
Cdd:PRK07658  14 VITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVI-HGEGRFFSAGADIKEFTSV---TEAEQATELAQLGQVTFE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 104 LLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFL---ADRGQiGLFTGLTGSIMTA 180
Cdd:PRK07658  89 RVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLpryVGKAK-ALEMMLTSEPITG 167

                        170       180
                 ....*....|....*....|....*..
gi 630601724 181 AGAYSIGWATHICEAQRdnVLQKVLNI 207
Cdd:PRK07658 168 AEALKWGLVNGVFPEET--LLDDAKKL 192
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 14-187 1.17e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 61.20  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  14 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEqvKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANK 93
Cdd:PRK07659   8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESS--AHIVVLRGNGRGFSAGGDIKMMLSSNDESKFDGVMN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  94 FFQQeyaLDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIGLFTG- 172
Cdd:PRK07659  86 TISE---IVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKR--VGENKAk 160

                        170
                 ....*....|....*...
gi 630601724 173 ---LTGSIMTAAGAYSIG 187
Cdd:PRK07659 161 qiiWEGKKLSATEALDLG 178
PLN02921 PLN02921
naphthoate synthase
 25-131 1.31e-10

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 61.73  E-value: 1.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDvrklrqlvinQEVETANKFFQQEYA---- 100
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGD----------QAVRGKDGYVGPDDAgrln 149

                         90       100       110
                 ....*....|....*....|....*....|....
gi 630601724 101 -LDLLLH--NYAKPVVVWGEGYVMGGGLGLFMAA 131
Cdd:PLN02921 150 vLDLQIQirRLPKPVIAMVAGYAVGGGHILHMVC 183
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 12-197 2.16e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 60.37  E-value: 2.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDVRKLRQLVINQEVETA 91
Cdd:PRK06190   4 PILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADP-AFCAGLDLKELGGDGSAYGAQDA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  92 NKffqqeyALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQIGLF- 170
Cdd:PRK06190  83 LP------NPSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRAr 156

                        170       180
                 ....*....|....*....|....*...
gi 630601724 171 -TGLTGSIMTAAGAYSIGWATHICEAQR 197
Cdd:PRK06190 157 rMSLTGDFLDAADALRAGLVTEVVPHDE 184
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
44-187 5.58e-10

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 61.07  E-value: 5.58e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  44 LLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALdllLHNYAKPVVVWGEGYVMGG 123
Cdd:PRK11154  39 VRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQQLFAE---IEALPIPVVAAIHGACLGG 115

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 124 GLGLFMAAPFRLVT--PYSRLAMPEINIGLYPDVGASRFLADRgqIGLFTG----LTGSIMTAAGAYSIG 187
Cdd:PRK11154 116 GLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRL--IGVSTAldmiLTGKQLRAKQALKLG 183
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 13-162 9.30e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 58.64  E-value: 9.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  13 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLV--------- 83
Cdd:PRK06072   1 MIKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEFAPDFaidlretfy 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  84 -INQEVETANKFFQQeyALDlllhnyakpvvvwgeGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA 162
Cdd:PRK06072  80 pIIREIRFSDKIYIS--AIN---------------GVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLL 142
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 17-327 1.81e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 57.83  E-value: 1.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  17 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANKFFQ 96
Cdd:PRK07260   7 EVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG-KVFSVGGDLVEMKRAVDEDDVQSLVKIAE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  97 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAsRFLADRGqIGLFTG---- 172
Cdd:PRK07260  86 LVNEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGG-LFLLTRA-IGLNRAthla 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 173 LTGSIMTAAGAYSIGWATHICEAQRdnvLQKVLNinwahypagdfraiddtlnslhrpvaagplqnsldvihsvcrgssf 252
Cdd:PRK07260 164 MTGEALTAEKALEYGFVYRVAESEK---LEKTCE---------------------------------------------- 194

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 630601724 253 eqdyQAIVSLRDASSDwlrqasenlqkgspSTAAITWLLWQwgKQVHSWDEVFDLEAQISEWKIRHPDFVEGVRA 327
Cdd:PRK07260 195 ----QLLKKLRRGSSN--------------SYAAIKSLVWE--SFFKGWEDYAKLELALQESLAFKEDFKEGVRA 249
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
11-151 2.58e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 57.40  E-value: 2.58e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  11 PDLVVEEAKNGWRIVRLNRPkSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVrKLRQLVInqevet 90
Cdd:PRK06495   3 MSQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADL-KGRPDVI------ 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 630601724  91 ankffqqEYALDLLLHNY------------AKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGL 151
Cdd:PRK06495  74 -------KGPGDLRAHNRrtrecfhairecAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL 139
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 10-187 2.88e-09

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 57.26  E-value: 2.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  10 HPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDvrkLRQLVINQEVE 89
Cdd:PRK08139   9 EAPLLLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHD---LKEMRAARGLA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  90 TANKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLY---PDVGASRFLADRGQ 166
Cdd:PRK08139  85 YFRALFARCSRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRNVPRKQA 164

                        170       180
                 ....*....|....*....|.
gi 630601724 167 IGLFtgLTGSIMTAAGAYSIG 187
Cdd:PRK08139 165 MEML--LTGEFIDAATAREWG 183
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 31-195 4.43e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 56.58  E-value: 4.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  31 KSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLvinqEVETANKFFQQEYALDLLLHNYAK 110
Cdd:PRK06143  26 GSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATL----DQASAEAFISRLRDLCDAVRHFPV 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 111 PVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLyPDV------------GASRFLAdrgqiglftgLTGSIM 178
Cdd:PRK06143 102 PVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVihaallprligwARTRWLL----------LTGETI 170

                        170
                 ....*....|....*..
gi 630601724 179 TAAGAYSIGWATHICEA 195
Cdd:PRK06143 171 DAAQALAWGLVDRVVPL 187
PLN02888 PLN02888
enoyl-CoA hydratase
 13-207 7.49e-09

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 55.91  E-value: 7.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  13 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDVRKLRQlVINQEVET-- 90
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGR-AFCSGVDLTAAEE-VFKGDVKDve 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  91 ANKFFQQEYAldlllhnyAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIGLF 170
Cdd:PLN02888  89 TDPVAQMERC--------RKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRI--IGAN 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 630601724 171 ----TGLTGSIMTAAGAYSIGWATHICEAqrDNVLQKVLNI 207
Cdd:PLN02888 159 rareVSLTAMPLTAETAERWGLVNHVVEE--SELLKKAREV 197
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
11-195 7.74e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 55.80  E-value: 7.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  11 PDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDeqVKAIWLDSTTPKaFCAGGDVRKLRQLVINQEVET 90
Cdd:PRK08150   1 PSLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHH 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  91 ANKFFQqeyALDLLLHNyAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQIGLF 170
Cdd:PRK08150  78 SRRWHR---VFDKIQYG-RVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARM 153

                        170       180
                 ....*....|....*....|....*..
gi 630601724 171 TG--LTGSIMTAAGAYSIGWATHICEA 195
Cdd:PRK08150 154 TDmmLTGRVYDAQEGERLGLAQYLVPA 180
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 24-197 6.87e-08

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 53.11  E-value: 6.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  24 IVRLNRPKSLHALDESIVTALLRVFEDFRDDEqVKAIWLDSTT-PKAFCAGGDVRKLRQ-----LVINQEVETANKFFQQ 97
Cdd:PRK11423  16 TITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSgSKVWSAGHDIHELPSggrdpLSYDDPLRQILRMIQK 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  98 eyaldlllhnYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGL-YPDVGASRFLADRGqIGLFTGL--T 174
Cdd:PRK11423  95 ----------FPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVpYNLSGILNFTNDAG-FHIVKEMffT 163

                        170       180
                 ....*....|....*....|...
gi 630601724 175 GSIMTAAGAYSIGWATHICEAQR 197
Cdd:PRK11423 164 ASPITAQRALAVGILNHVVEVEE 186
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
13-190 1.08e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 52.38  E-value: 1.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  13 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETAN 92
Cdd:PRK07827   7 LVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVL-THTGGTFCAGADLSEAGGGGGDPYDAAVA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  93 KFFQQEYALDLLLHnYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDV------------GASRF 160
Cdd:PRK07827  86 RAREMTALLRAIVE-LPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIisltllprlsprAAARY 164

                        170       180       190
                 ....*....|....*....|....*....|
gi 630601724 161 LadrgqiglftgLTGSIMTAAGAYSIGWAT 190
Cdd:PRK07827 165 Y-----------LTGEKFGAAEAARIGLVT 183
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
11-192 4.38e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 50.49  E-value: 4.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  11 PDLVVEEaKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQlviNQEVET 90
Cdd:PRK07799   5 PHALVEQ-RGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATK---KPPGDS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  91 ANKFFQQEYALDLLL--HNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPdVGASRFLADRgQI- 167
Cdd:PRK07799  80 FKDGSYDPSRIDALLkgRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVRLVR-QIp 157

                        170       180
                 ....*....|....*....|....*...
gi 630601724 168 ---GLFTGLTGSIMTAAGAYSIGWATHI 192
Cdd:PRK07799 158 ytvACDLLLTGRHITAAEAKEIGLIGHV 185
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
 12-162 4.78e-07

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 50.62  E-value: 4.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724   12 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDvRKLRQlvinqevETA 91
Cdd:TIGR01929   3 DIRYEKSTDGIAKITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGD-QKVRG-------DYG 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 630601724   92 NKFFQQEYALDLL-----LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA 162
Cdd:TIGR01929  75 YIDDSGVHRLNVLdvqrqIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMA 150
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
25-187 8.69e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 49.97  E-value: 8.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKL----RQLVINQEVETANKFFQQeyA 100
Cdd:PRK06142  19 VTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVL-SGSGKHFSYGIDLPAMagvfGQLGKDGLARPRTDLRRE--I 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 101 LDL-----LLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGA------------SRFLAd 163
Cdd:PRK06142  96 LRLqaainAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSlqrlpriigdghLRELA- 174

                        170       180
                 ....*....|....*....|....
gi 630601724 164 rgqiglftgLTGSIMTAAGAYSIG 187
Cdd:PRK06142 175 ---------LTGRDIDAAEAEKIG 189
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 27-124 1.54e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 49.12  E-value: 1.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  27 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGD--VRKLRQLVINQEVETANkffqqeyALDL- 103
Cdd:PRK07396  28 INRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDqkVRGYGGYVDDDGVPRLN-------VLDLq 100

                         90       100
                 ....*....|....*....|..
gi 630601724 104 -LLHNYAKPVVVWGEGYVMGGG 124
Cdd:PRK07396 101 rLIRTCPKPVIAMVAGYAIGGG 122
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
27-197 2.12e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 48.52  E-value: 2.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  27 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVI---NQEVETANKFFQQEYALDL 103
Cdd:PRK07468  20 LNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTadrATRIEEARRLAMMLKALND 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 104 LlhnyAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQI-GLFTGLTGSIMTAAG 182
Cdd:PRK07468  99 L----PKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEAnARRVFMSARLFDAEE 174

                        170
                 ....*....|....*
gi 630601724 183 AYSIGWATHICEAQR 197
Cdd:PRK07468 175 AVRLGLLSRVVPAER 189
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
24-157 9.46e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 46.50  E-value: 9.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  24 IVRLNRPKSLHAL-DESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETANkfFQQEYA-- 100
Cdd:PRK09245  15 TLTMNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKDMRARVGAFGGSPAD--IRQGYRhg 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 630601724 101 ---LDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYP-DVGA 157
Cdd:PRK09245  92 iqrIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPgDGGA 152
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 10-182 2.19e-05

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 45.34  E-value: 2.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  10 HPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVE 89
Cdd:PRK07110   3 MKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVIL-TGYPNYFATGGTQEGLLSLQTGKGTF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  90 TANKFFqqeyaldLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIGL 169
Cdd:PRK07110  82 TEANLY-------SLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEK--LGL 152

                        170
                 ....*....|...
gi 630601724 170 FTGLTgSIMTAAG 182
Cdd:PRK07110 153 ALGQE-MLLTARY 164
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 70-163 7.00e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 43.67  E-value: 7.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  70 FCAGGDVRKLRQLViNQEVETANKFFQQeyALDLLLhNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINI 149
Cdd:PRK05869  64 FSAGDDMPELRTLS-AQEADTAARVRQQ--AVDAVA-AIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILA 139

                         90
                 ....*....|....
gi 630601724 150 GLYPDVGASRFLAD 163
Cdd:PRK05869 140 GLAPSGDGMARLTR 153
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 25-192 7.40e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 43.86  E-value: 7.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSLHALDESIVTALLRVFEDfRDDEQVKAIWLDSTTPkAFCAGGDVrklrqlvinqevetANKFFQQEY--ALD 102
Cdd:PRK07854  13 IELQRPERRNALNAELCEELREAVRK-AVDESARAIVLTGQGT-VFCAGADL--------------SGDVYADDFpdALI 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 103 LLLHNY-AKPVVVWGE--GYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPD----------VGASR----FLADR- 164
Cdd:PRK07854  77 EMLHAIdAAPVPVIAAinGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDnwtirrlsslVGGGRaramLLGAEk 156

                        170       180       190
                 ....*....|....*....|....*....|
gi 630601724 165 --GQIGLFTGLTGSIMTAAGAysIGWATHI 192
Cdd:PRK07854 157 ltAEQALATGMANRIGTLADA--QAWAAEI 184
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 13-187 1.57e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 42.90  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  13 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKlrqlviNQEVETAN 92
Cdd:PRK05864  11 VLVDHPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVL-TGAGRGFSSGADHKS------AGVVPHVE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  93 KFFQQEYALD---------LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLY-PDVGASrFLA 162
Cdd:PRK05864  84 GLTRPTYALRsmellddviLALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLS-YLL 162

                        170       180
                 ....*....|....*....|....*....
gi 630601724 163 DRGqIGLFTG----LTGSIMTAAGAYSIG 187
Cdd:PRK05864 163 PRA-IGSSRAfeimLTGRDVDAEEAERIG 190
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 24-187 2.06e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 42.69  E-value: 2.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  24 IVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYA--- 100
Cdd:PRK08260  16 TITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLSAGGNTFDLDAPRTPVEADEEDRAdps 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 101 ----------LDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgQIGLF 170
Cdd:PRK08260  95 ddgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPR--LVGLQ 172

                        170       180
                 ....*....|....*....|.
gi 630601724 171 TGL----TGSIMTAAGAYSIG 187
Cdd:PRK08260 173 TALewvySGRVFDAQEALDGG 193
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 27-156 2.15e-04

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 42.58  E-value: 2.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  27 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLV----------INQEVETANKFFQ 96
Cdd:PLN02664  23 LNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTLNSISeqsssgdrgrSGERLRRKIKFLQ 101

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  97 QEYALdllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVG 156
Cdd:PLN02664 102 DAITA---IEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLG 158
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
17-187 3.05e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 41.88  E-value: 3.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  17 EAKNGWRIVRLNRPKsLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANKffq 96
Cdd:PRK07938   7 TPEPGIAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLRAEG-RGFNAGVDIKELQATPGFTALIDANR--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  97 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEIniglypdvgasrflaDRGQIGLFTGL--- 173
Cdd:PRK07938  82 GCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEV---------------DRGALGAATHLqrl 146

                        170       180
                 ....*....|....*....|....*
gi 630601724 174 -----------TGSIMTAAGAYSIG 187
Cdd:PRK07938 147 vpqhlmralffTAATITAAELHHFG 171
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
23-131 4.31e-04

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 41.55  E-value: 4.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  23 RIVrLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETAnkfFQQEyALD 102
Cdd:PRK07327  24 EIV-LNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDFEVRAR---VWRE-ARD 97

                         90       100       110
                 ....*....|....*....|....*....|.
gi 630601724 103 LLLH--NYAKPVVVWGEGYVMGGGLGLFMAA 131
Cdd:PRK07327  98 LVYNviNCDKPIVSAIHGPAVGAGLVAALLA 128
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
27-153 5.02e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 41.21  E-value: 5.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  27 LNRPKSLHALDESIVTALLRVFEDFRDDeqVKAIWLDSTtPKAFCAGGDVRKLRQLVINQEVETankfFQQEYALDLLLH 106
Cdd:PRK07112  19 LHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGL-PEVFCFGADFSAIAEKPDAGRADL----IDAEPLYDLWHR 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 630601724 107 NYAKPVVVWG--EGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYP 153
Cdd:PRK07112  92 LATGPYVTIAhvRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP 140
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 24-187 6.70e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 41.06  E-value: 6.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  24 IVRLNRPKSlHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKF---FQQeya 100
Cdd:PRK09076  15 ILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFgeaFEA--- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 101 ldllLHNYaKPVVVWG-EGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgqiglFTG------- 172
Cdd:PRK09076  91 ----LSAF-RGVSIAAiNGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPW------LVGegwakrm 159

                        170
                 ....*....|....*.
gi 630601724 173 -LTGSIMTAAGAYSIG 187
Cdd:PRK09076 160 iLCGERVDAATALRIG 175
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
13-158 7.66e-04

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 41.39  E-value: 7.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  13 LVVEEAKNGwrIVRL--NRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDVRKLRQL------VI 84
Cdd:PRK11730   8 LQVDWLEDG--IAELvfDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKD-AFIVGADITEFLSLfaapeeEL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 630601724  85 NQEVETANKFFQQEYALDLllhnyakPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS 158
Cdd:PRK11730  85 SQWLHFANSIFNRLEDLPV-------PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGT 151
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
 24-77 8.94e-04

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 40.57  E-value: 8.94e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 630601724  24 IVRL--NRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPK-----AFCAGGDVR 77
Cdd:COG0447   28 IARIaiNRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGPSkdggwAFCSGGDQR 88
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
17-187 9.85e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 40.55  E-value: 9.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  17 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKA-IWLDstTPKAFCAGGDVRKLrqlvinQEVETANKFF 95
Cdd:PRK06023  11 GAHPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAhVFLG--TEGCFSAGNDMQDF------LAAAMGGTSF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  96 QQEyALDLL--LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASrFLADR--GQIGLFT 171
Cdd:PRK06023  83 GSE-ILDFLiaLAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSS-LLAPRlmGHQRAFA 160

                        170
                 ....*....|....*..
gi 630601724 172 GLT-GSIMTAAGAYSIG 187
Cdd:PRK06023 161 LLAlGEGFSAEAAQEAG 177
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 27-155 2.57e-03

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 39.02  E-value: 2.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  27 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQ---LVINQEVETANKFFQQEYALdl 103
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLAWMQQsadLDYNTNLDDARELAELMYNL-- 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 630601724 104 llHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDV 155
Cdd:PRK05674  98 --YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAV 147
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 62-164 6.01e-03

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 37.97  E-value: 6.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  62 LDSTTPKAFCAGGDVRKLRQLVINQEVETAnkffqQEYA---LDLLLHNY---AKPVVVWG--EGYVMGGGLGLFMAAPF 133
Cdd:PRK08788  71 LASDVPGVFNLGGDLALFAELIRAGDRDAL-----LAYAracVDGVHAFHrgfGAGAISIAlvQGDALGGGFEAALSHHT 145

                         90       100       110
                 ....*....|....*....|....*....|.
gi 630601724 134 RLVTPYSRLAMPEINIGLYPDVGASRFLADR 164
Cdd:PRK08788 146 IIAERGAKMGFPEILFNLFPGMGAYSFLARR 176
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 25-187 7.74e-03

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 37.68  E-value: 7.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724  25 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALDLL 104
Cdd:PRK09120  21 VTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVL-TGAGDAWSAGMDLKEYFRETDAQPEILQERIRREAYGWWRR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630601724 105 LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD--RGQIGLFTGLTGSIMTAAG 182
Cdd:PRK09120 100 LRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADtvGHRDALYYIMTGETFTGRK 179


                 ....*
gi 630601724 183 AYSIG 187
Cdd:PRK09120 180 AAEMG 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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