Eukaryotic translation initiation factor 5, partial [Cucurbita argyrosperma subsp. sororia]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
eIF2B_5 | smart00653 | domain present in translation initiation factor eIF2B and eIF5; |
60-174 | 1.06e-49 | |||
domain present in translation initiation factor eIF2B and eIF5; : Pssm-ID: 214764 Cd Length: 110 Bit Score: 170.89 E-value: 1.06e-49
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W2_eIF5 | cd11561 | C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
345-484 | 8.93e-37 | |||
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats. : Pssm-ID: 211399 Cd Length: 157 Bit Score: 135.82 E-value: 8.93e-37
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Auxin_resp | pfam06507 | Auxin response factor; A conserved region of auxin-responsive transcription factors. |
727-800 | 1.25e-28 | |||
Auxin response factor; A conserved region of auxin-responsive transcription factors. : Pssm-ID: 428981 Cd Length: 83 Bit Score: 109.55 E-value: 1.25e-28
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B3 | pfam02362 | B3 DNA binding domain; This is a family of plant transcription factors with various roles in ... |
561-663 | 3.10e-23 | |||
B3 DNA binding domain; This is a family of plant transcription factors with various roles in development, the aligned region corresponds the B3 DNA binding domain as described in this domain is found in VP1/AB13 transcription factors. Some proteins also have a second AP2 DNA binding domain pfam00847 such as RAV1. DNA binding activity was demonstrated by. : Pssm-ID: 396783 [Multi-domain] Cd Length: 101 Bit Score: 95.13 E-value: 3.10e-23
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Name | Accession | Description | Interval | E-value | |||
eIF2B_5 | smart00653 | domain present in translation initiation factor eIF2B and eIF5; |
60-174 | 1.06e-49 | |||
domain present in translation initiation factor eIF2B and eIF5; Pssm-ID: 214764 Cd Length: 110 Bit Score: 170.89 E-value: 1.06e-49
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eIF-5_eIF-2B | pfam01873 | Domain found in IF2B/IF5; This family includes the N terminus of eIF-5, and the C terminus of ... |
58-172 | 8.26e-46 | |||
Domain found in IF2B/IF5; This family includes the N terminus of eIF-5, and the C terminus of eIF-2 beta. This region corresponds to the whole of the archaebacterial eIF-2 beta homolog. The region contains a putative zinc binding C4 finger. Pssm-ID: 426485 Cd Length: 115 Bit Score: 159.99 E-value: 8.26e-46
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W2_eIF5 | cd11561 | C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
345-484 | 8.93e-37 | |||
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats. Pssm-ID: 211399 Cd Length: 157 Bit Score: 135.82 E-value: 8.93e-37
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Auxin_resp | pfam06507 | Auxin response factor; A conserved region of auxin-responsive transcription factors. |
727-800 | 1.25e-28 | |||
Auxin response factor; A conserved region of auxin-responsive transcription factors. Pssm-ID: 428981 Cd Length: 83 Bit Score: 109.55 E-value: 1.25e-28
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B3 | pfam02362 | B3 DNA binding domain; This is a family of plant transcription factors with various roles in ... |
561-663 | 3.10e-23 | |||
B3 DNA binding domain; This is a family of plant transcription factors with various roles in development, the aligned region corresponds the B3 DNA binding domain as described in this domain is found in VP1/AB13 transcription factors. Some proteins also have a second AP2 DNA binding domain pfam00847 such as RAV1. DNA binding activity was demonstrated by. Pssm-ID: 396783 [Multi-domain] Cd Length: 101 Bit Score: 95.13 E-value: 3.10e-23
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eIF5C | smart00515 | Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
400-484 | 4.11e-20 | |||
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; Pssm-ID: 214705 Cd Length: 83 Bit Score: 85.42 E-value: 4.11e-20
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B3 | smart01019 | B3 DNA binding domain; Two DNA binding proteins, RAV1 and RAV2 from Arabidopsis thaliana ... |
561-662 | 2.64e-19 | |||
B3 DNA binding domain; Two DNA binding proteins, RAV1 and RAV2 from Arabidopsis thaliana contain two distinct amino acid sequence domains found only in higher plant species. The N-terminal regions of RAV1 and RAV2 are homologous to the AP2 DNA-binding domain (see ) present in a family of transcription factors, while the C-terminal region exhibits homology to the highly conserved C-terminal domain, designated B3, of VP1/ABI3 transcription factors. The AP2 and B3-like domains of RAV1 bind autonomously to the CAACA and CACCTG motifs, respectively, and together achieve a high affinity and specificity of binding. It has been suggested that the AP2 and B3-like domains of RAV1 are connected by a highly flexible structure enabling the two domains to bind to the CAACA and CACCTG motifs in various spacings and orientations. Pssm-ID: 214977 Cd Length: 96 Bit Score: 83.50 E-value: 2.64e-19
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B3_DNA | cd10017 | Plant-specific B3-DNA binding domain; The plant-specific B3 DNA binding domain superfamily ... |
560-661 | 3.01e-19 | |||
Plant-specific B3-DNA binding domain; The plant-specific B3 DNA binding domain superfamily includes the well-characterized auxin response factor (ARF) and the LAV (Leafy cotyledon2 [LEC2]-Abscisic acid insensitive3 [ABI3]-VAL) families, as well as the RAV (Related to ABI3 and VP1) and REM (REproductive Meristem) families. LEC2 and ABI3 have been shown to be involved in seed development, while other members of the LAV family seem to have a more general role, being expressed in many organs during plant development. Members of the ARF family bind to the auxin response element and depending on presence of an activation or repression domain, they activate or repress transcription. RAV and REM families are less studied B3 protein famillies. Pssm-ID: 197383 Cd Length: 98 Bit Score: 83.53 E-value: 3.01e-19
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W2 | pfam02020 | eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
413-484 | 1.07e-17 | |||
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors. Pssm-ID: 460415 Cd Length: 76 Bit Score: 78.34 E-value: 1.07e-17
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PRK03988 | PRK03988 | translation initiation factor IF-2 subunit beta; Validated |
62-172 | 1.09e-13 | |||
translation initiation factor IF-2 subunit beta; Validated Pssm-ID: 235189 Cd Length: 138 Bit Score: 69.17 E-value: 1.09e-13
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Name | Accession | Description | Interval | E-value | |||
eIF2B_5 | smart00653 | domain present in translation initiation factor eIF2B and eIF5; |
60-174 | 1.06e-49 | |||
domain present in translation initiation factor eIF2B and eIF5; Pssm-ID: 214764 Cd Length: 110 Bit Score: 170.89 E-value: 1.06e-49
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eIF-5_eIF-2B | pfam01873 | Domain found in IF2B/IF5; This family includes the N terminus of eIF-5, and the C terminus of ... |
58-172 | 8.26e-46 | |||
Domain found in IF2B/IF5; This family includes the N terminus of eIF-5, and the C terminus of eIF-2 beta. This region corresponds to the whole of the archaebacterial eIF-2 beta homolog. The region contains a putative zinc binding C4 finger. Pssm-ID: 426485 Cd Length: 115 Bit Score: 159.99 E-value: 8.26e-46
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W2_eIF5 | cd11561 | C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase ... |
345-484 | 8.93e-37 | |||
C-terminal W2 domain of eukaryotic translation initiation factor 5; eIF5 functions as a GTPase acceleration protein (GAP), as well as a GDP dissociation inhibitor (GDI) during translational initiation in eukaryotes. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats. Pssm-ID: 211399 Cd Length: 157 Bit Score: 135.82 E-value: 8.93e-37
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Auxin_resp | pfam06507 | Auxin response factor; A conserved region of auxin-responsive transcription factors. |
727-800 | 1.25e-28 | |||
Auxin response factor; A conserved region of auxin-responsive transcription factors. Pssm-ID: 428981 Cd Length: 83 Bit Score: 109.55 E-value: 1.25e-28
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B3 | pfam02362 | B3 DNA binding domain; This is a family of plant transcription factors with various roles in ... |
561-663 | 3.10e-23 | |||
B3 DNA binding domain; This is a family of plant transcription factors with various roles in development, the aligned region corresponds the B3 DNA binding domain as described in this domain is found in VP1/AB13 transcription factors. Some proteins also have a second AP2 DNA binding domain pfam00847 such as RAV1. DNA binding activity was demonstrated by. Pssm-ID: 396783 [Multi-domain] Cd Length: 101 Bit Score: 95.13 E-value: 3.10e-23
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eIF5C | smart00515 | Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; |
400-484 | 4.11e-20 | |||
Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5; Pssm-ID: 214705 Cd Length: 83 Bit Score: 85.42 E-value: 4.11e-20
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B3 | smart01019 | B3 DNA binding domain; Two DNA binding proteins, RAV1 and RAV2 from Arabidopsis thaliana ... |
561-662 | 2.64e-19 | |||
B3 DNA binding domain; Two DNA binding proteins, RAV1 and RAV2 from Arabidopsis thaliana contain two distinct amino acid sequence domains found only in higher plant species. The N-terminal regions of RAV1 and RAV2 are homologous to the AP2 DNA-binding domain (see ) present in a family of transcription factors, while the C-terminal region exhibits homology to the highly conserved C-terminal domain, designated B3, of VP1/ABI3 transcription factors. The AP2 and B3-like domains of RAV1 bind autonomously to the CAACA and CACCTG motifs, respectively, and together achieve a high affinity and specificity of binding. It has been suggested that the AP2 and B3-like domains of RAV1 are connected by a highly flexible structure enabling the two domains to bind to the CAACA and CACCTG motifs in various spacings and orientations. Pssm-ID: 214977 Cd Length: 96 Bit Score: 83.50 E-value: 2.64e-19
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B3_DNA | cd10017 | Plant-specific B3-DNA binding domain; The plant-specific B3 DNA binding domain superfamily ... |
560-661 | 3.01e-19 | |||
Plant-specific B3-DNA binding domain; The plant-specific B3 DNA binding domain superfamily includes the well-characterized auxin response factor (ARF) and the LAV (Leafy cotyledon2 [LEC2]-Abscisic acid insensitive3 [ABI3]-VAL) families, as well as the RAV (Related to ABI3 and VP1) and REM (REproductive Meristem) families. LEC2 and ABI3 have been shown to be involved in seed development, while other members of the LAV family seem to have a more general role, being expressed in many organs during plant development. Members of the ARF family bind to the auxin response element and depending on presence of an activation or repression domain, they activate or repress transcription. RAV and REM families are less studied B3 protein famillies. Pssm-ID: 197383 Cd Length: 98 Bit Score: 83.53 E-value: 3.01e-19
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W2 | pfam02020 | eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of ... |
413-484 | 1.07e-17 | |||
eIF4-gamma/eIF5/eIF2-epsilon; This domain of unknown function is found at the C-terminus of several translation initiation factors. Pssm-ID: 460415 Cd Length: 76 Bit Score: 78.34 E-value: 1.07e-17
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W2_eIF2B_epsilon | cd11558 | C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a ... |
362-484 | 5.31e-15 | |||
C-terminal W2 domain of eukaryotic translation initiation factor 2B epsilon; eIF2B is a heteropentameric complex which functions as a guanine nucleotide exchange factor in the recycling of eIF-2 during the initiation of translation in eukaryotes. The epsilon and gamma subunits are sequence similar and both are essential in yeast. Epsilon appears to be the catalytically active subunit, with gamma enhancing its activity. The C-terminal domain of the eIF2B epsilon subunit contains bipartite motifs rich in acidic and aromatic residues, which are responsible for the interaction with eIF2. The structure of the domain resembles that of a set of concatenated HEAT repeats. Pssm-ID: 211396 Cd Length: 169 Bit Score: 73.83 E-value: 5.31e-15
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PRK03988 | PRK03988 | translation initiation factor IF-2 subunit beta; Validated |
62-172 | 1.09e-13 | |||
translation initiation factor IF-2 subunit beta; Validated Pssm-ID: 235189 Cd Length: 138 Bit Score: 69.17 E-value: 1.09e-13
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PRK12336 | PRK12336 | translation initiation factor IF-2 subunit beta; Provisional |
62-172 | 7.95e-12 | |||
translation initiation factor IF-2 subunit beta; Provisional Pssm-ID: 183451 [Multi-domain] Cd Length: 201 Bit Score: 65.35 E-value: 7.95e-12
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W2_eIF5C_like | cd11560 | C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; ... |
412-484 | 9.40e-06 | |||
C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins; eIF5C appears to be essential for the initiation of protein translation; its actual function, and specifically that of the C-terminal W2 domain, are not well understood. The Drosophila ortholog, kra (krasavietz) or exba (extra bases), may be involved in translational inhibition in neural development. The structure of this C-terminal domain resembles that of a set of concatenated HEAT repeats. Pssm-ID: 211398 [Multi-domain] Cd Length: 194 Bit Score: 47.21 E-value: 9.40e-06
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W2 | cd11473 | C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of ... |
311-457 | 6.55e-04 | |||
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; This domain is found at the C-terminus of several translation initiation factors, including the epsilon chain of eIF2b, where it has been found to catalyze the conversion of eIF2.GDP to its active eIF2.GTP form. The structure of the domain resembles that of a set of concatenated HEAT repeats. Pssm-ID: 211395 Cd Length: 135 Bit Score: 40.92 E-value: 6.55e-04
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EcoRII_N | cd10016 | N-terminal domain of type IIE restriction endonuclease EcoRII and similar proteins; N-terminal ... |
561-657 | 9.52e-04 | |||
N-terminal domain of type IIE restriction endonuclease EcoRII and similar proteins; N-terminal domain of type IIE restriction endonuclease EcoRII and similar proteins. Type II restriction endonucleases are components of restriction modification (RM) systems that protect bacteria and archaea against invading foreign DNA. They usually function as homodimers or homotetramers that cleave DNA at defined sites of 4 to 8 bp in length, and they require Mg2+, not ATP or GTP, for catalysis. EcoRII is specific for the 5'-CCWGG sequence (W stands for A or T). EcoRII consists of 2 domains, the C-terminal catalytic/dimerization domain (EcoRII-C), and the N-terminal effector DNA binding domain (EcoRII-N). To be catalytically active, EcoRII has to form a dimer. Pssm-ID: 197382 Cd Length: 142 Bit Score: 40.44 E-value: 9.52e-04
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BfiI_C_EcoRII_N_B3 | cd10015 | DNA binding domains of BfiI, EcoRII and plant B3 proteins; This family contains the N-terminal ... |
561-659 | 2.19e-03 | |||
DNA binding domains of BfiI, EcoRII and plant B3 proteins; This family contains the N-terminal DNA binding domain of type IIE restriction endonuclease EcoRII-like proteins, the C-terminal DNA binding domain of type IIS restriction endonuclease BfiI-like proteins and plant-specific B3 proteins. Type II restriction endonucleases are components of restriction modification (RM) systems that protect bacteria and archaea against invading foreign DNA. They usually function as homodimers or homotetramers that cleave DNA at defined sites of 4 to 8 bp in length, and they require Mg2+, not ATP or GTP, for catalysis. EcoRII is specific for the 5'-CCWGG sequence (W stands for A or T). EcoRII consists of 2 domains, the C-terminal catalytic/dimerization domain (EcoRII-C), and the N-terminal effector DNA binding domain (EcoRII-N). BfiI is unique in cleaving DNA at fixed positions downstream of an asymmetric sequence in the absence of Mg2+. BfiI consists of two discrete domains with distinct functions: an N-terminal catalytic domain with non-specific nuclease activity and dimerization function that is more closely related to Nuc, an EDTA-resistant nuclease from the phospholipase D (PLD) superfamily; and a C-terminal domain that specifically recognizes its target sequences, 5'-ACTGGG-3'. B3 proteins are a family of plant-specific transcription factors, involved in a great variety of processes, including seed development and auxin response. Pssm-ID: 197381 Cd Length: 109 Bit Score: 38.77 E-value: 2.19e-03
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Blast search parameters | ||||
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