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Conserved domains on  [gi|2047911347|gb|KAG6584155|]
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Protein transport protein Sec61 subunit gamma, partial [Cucurbita argyrosperma subsp. sororia]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 1575)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

CATH:  1.20.5.1030
Gene Ontology:  GO:0043952|GO:0065002|GO:0006605
SCOP:  4005885
TCDB:  3.A.5

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
secE super family cl00481
preprotein translocase subunit SecE; Reviewed
 79-123 8.29e-15

preprotein translocase subunit SecE; Reviewed


The actual alignment was detected with superfamily member PTZ00478:

Pssm-ID: 469787  Cd Length: 81  Bit Score: 64.35  E-value: 8.29e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2047911347  79 VVDPLREFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVG 123
Cdd:PTZ00478   19 VVSGVQEFANDSRRLIRKCTKPDAKEYTNIAYACSVGFFIMGFIG 63
 
Name Accession Description Interval E-value
PTZ00478 PTZ00478
Sec superfamily; Provisional
 79-123 8.29e-15

Sec superfamily; Provisional


Pssm-ID: 185656  Cd Length: 81  Bit Score: 64.35  E-value: 8.29e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2047911347  79 VVDPLREFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVG 123
Cdd:PTZ00478   19 VVSGVQEFANDSRRLIRKCTKPDAKEYTNIAYACSVGFFIMGFIG 63
secE_euk_arch TIGR00327
protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes ...
 80-123 1.60e-08

protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes archaeal SEC61-like and eukaryotic SEC61 but not bacterial secE proteins, for which a Pfam pfam00584 (SecE) has been created. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273016  Cd Length: 61  Bit Score: 47.84  E-value: 1.60e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2047911347  80 VDPLREFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVG 123
Cdd:TIGR00327   3 IEAPVEFIKEGTRVLAVCKKPDLEEYLKVAKVTGIGIIIVGIIG 46
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 84-127 3.75e-07

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 43.96  E-value: 3.75e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2047911347  84 REFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVGLGHD 127
Cdd:pfam00584   1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVD 44
 
Name Accession Description Interval E-value
PTZ00478 PTZ00478
Sec superfamily; Provisional
 79-123 8.29e-15

Sec superfamily; Provisional


Pssm-ID: 185656  Cd Length: 81  Bit Score: 64.35  E-value: 8.29e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2047911347  79 VVDPLREFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVG 123
Cdd:PTZ00478   19 VVSGVQEFANDSRRLIRKCTKPDAKEYTNIAYACSVGFFIMGFIG 63
secE_euk_arch TIGR00327
protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes ...
 80-123 1.60e-08

protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic; This model describes archaeal SEC61-like and eukaryotic SEC61 but not bacterial secE proteins, for which a Pfam pfam00584 (SecE) has been created. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273016  Cd Length: 61  Bit Score: 47.84  E-value: 1.60e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2047911347  80 VDPLREFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVG 123
Cdd:TIGR00327   3 IEAPVEFIKEGTRVLAVCKKPDLEEYLKVAKVTGIGIIIVGIIG 46
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 84-127 3.75e-07

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 43.96  E-value: 3.75e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2047911347  84 REFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVGLGHD 127
Cdd:pfam00584   1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVD 44
secE PRK09400
preprotein translocase subunit SecE; Reviewed
 83-123 1.03e-05

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236497  Cd Length: 61  Bit Score: 40.61  E-value: 1.03e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2047911347  83 LREFAKDSVRLVKRCHKPDRKEFTKVAVRTAIGFVVMGFVG 123
Cdd:PRK09400   10 VKNFLEDYKRVLKVARKPTREEFLLVAKVTGLGILLIGLIG 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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