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Conserved domains on  [gi|2047910773|gb|KAG6583581|]
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CASP-like protein 5A2, partial [Cucurbita argyrosperma subsp. sororia]

Protein Classification

CASP domain-containing protein( domain architecture ID 10517609)

CASP (Casparian strip membrane protein) domain-containing protein similar to CASPs, which are four-membrane-span proteins that mediate the deposition of Casparian strips in the endodermis by recruiting the lignin polymerization machinery

Gene Ontology:  GO:0016020
PubMed:  21593871

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CASP_dom pfam04535
Casparian strip membrane protein domain; This domain is found mainly in plant proteins known ...
 32-161 2.95e-23

Casparian strip membrane protein domain; This domain is found mainly in plant proteins known as Casparian strip membrane proteins (CASPs) and CASP-like proteins (CASPLs). CASPs are four-membrane-span proteins that mediate the deposition of Casparian strips in the endodermis by recruiting the lignin polymerization machinery. Interestingly, the CASP first extracellular loop was found conserved in euphyllophytes but absent in plants lacking Casparian strips.


:

Pssm-ID: 367980  Cd Length: 150  Bit Score: 91.22  E-value: 2.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773  32 GMPGTRGGLALRFFQFLFAAAALVVMATTSD------------FPSVTAFCYLVAAAGLQSLWSLFLAFIDIYALLVKRs 99
Cdd:pfam04535   1 GRPLRLAELVLRLAAFVLALAAAVVMGTNKQtksfffiqfkakFSDYPAFRYLVVANAIAAGYSLLQLVLSVYSLSRKR- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773 100 LQNCRIVSLFTIGDGITSTLTFAAACASAGIT-VLIDNDIGS-----CSENH--CVQFETATAMAFISWF 161
Cdd:pfam04535  80 LRSAALAWLLFILDQVMAYLLLSAASAAAAIVyLARNGNSHAqwlkiCNQFGrfCNRVAASVALSFLAFL 149
 
Name Accession Description Interval E-value
CASP_dom pfam04535
Casparian strip membrane protein domain; This domain is found mainly in plant proteins known ...
 32-161 2.95e-23

Casparian strip membrane protein domain; This domain is found mainly in plant proteins known as Casparian strip membrane proteins (CASPs) and CASP-like proteins (CASPLs). CASPs are four-membrane-span proteins that mediate the deposition of Casparian strips in the endodermis by recruiting the lignin polymerization machinery. Interestingly, the CASP first extracellular loop was found conserved in euphyllophytes but absent in plants lacking Casparian strips.


Pssm-ID: 367980  Cd Length: 150  Bit Score: 91.22  E-value: 2.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773  32 GMPGTRGGLALRFFQFLFAAAALVVMATTSD------------FPSVTAFCYLVAAAGLQSLWSLFLAFIDIYALLVKRs 99
Cdd:pfam04535   1 GRPLRLAELVLRLAAFVLALAAAVVMGTNKQtksfffiqfkakFSDYPAFRYLVVANAIAAGYSLLQLVLSVYSLSRKR- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773 100 LQNCRIVSLFTIGDGITSTLTFAAACASAGIT-VLIDNDIGS-----CSENH--CVQFETATAMAFISWF 161
Cdd:pfam04535  80 LRSAALAWLLFILDQVMAYLLLSAASAAAAIVyLARNGNSHAqwlkiCNQFGrfCNRVAASVALSFLAFL 149
 
Name Accession Description Interval E-value
CASP_dom pfam04535
Casparian strip membrane protein domain; This domain is found mainly in plant proteins known ...
 32-161 2.95e-23

Casparian strip membrane protein domain; This domain is found mainly in plant proteins known as Casparian strip membrane proteins (CASPs) and CASP-like proteins (CASPLs). CASPs are four-membrane-span proteins that mediate the deposition of Casparian strips in the endodermis by recruiting the lignin polymerization machinery. Interestingly, the CASP first extracellular loop was found conserved in euphyllophytes but absent in plants lacking Casparian strips.


Pssm-ID: 367980  Cd Length: 150  Bit Score: 91.22  E-value: 2.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773  32 GMPGTRGGLALRFFQFLFAAAALVVMATTSD------------FPSVTAFCYLVAAAGLQSLWSLFLAFIDIYALLVKRs 99
Cdd:pfam04535   1 GRPLRLAELVLRLAAFVLALAAAVVMGTNKQtksfffiqfkakFSDYPAFRYLVVANAIAAGYSLLQLVLSVYSLSRKR- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773 100 LQNCRIVSLFTIGDGITSTLTFAAACASAGIT-VLIDNDIGS-----CSENH--CVQFETATAMAFISWF 161
Cdd:pfam04535  80 LRSAALAWLLFILDQVMAYLLLSAASAAAAIVyLARNGNSHAqwlkiCNQFGrfCNRVAASVALSFLAFL 149
MARVEL pfam01284
Membrane-associating domain; MARVEL domain-containing proteins are often found in ...
 55-169 6.27e-04

Membrane-associating domain; MARVEL domain-containing proteins are often found in lipid-associating proteins - such as Occludin and MAL family proteins. It may be part of the machinery of membrane apposition events, such as transport vesicle biogenesis.


Pssm-ID: 366555  Cd Length: 136  Bit Score: 38.47  E-value: 6.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2047910773  55 VVMATTSDFPSVT-----AFCYLVAAAGLQSLWSLFLAFIDIYALLVKRSLqncRIVSLFTIGDGITSTLTFAAACASA- 128
Cdd:pfam01284  19 IVLGLIASLIAYAgsypsAVNFAVFVAVFSFLIALFFLLLYLFGYSYFPSI---AWPLIDLIFDALAALFWLAAFIALAa 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2047910773 129 GITVLIDNDIGSCSENHCVQFETATAMAFISWFTALPSFFM 169
Cdd:pfam01284  96 ALRGHSENQGSGDLTRRCRAAQAAIAFGFFAWLLFLASAVL 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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