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Conserved domains on  [gi|1775891392|gb|KAE8650977|]
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hypothetical protein Csa_000712 [Cucumis sativus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 1000136)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
256-972 2.32e-63

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 233.97  E-value: 2.32e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  256 DFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLlQGSLPD--FPSSRPLQTLVLQGTKFSGTLPEsiGYFENLT 333
Cdd:PLN00113    67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQL-SGPIPDdiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLE 143
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNRLngsllstkweelpnlvnldlrnn 412
Cdd:PLN00113   144 TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPnSLTNLTSLEFLTLASNQL----------------------- 200
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  413 siTGNVPSSLFNLQTIRKIQLNYNLFSGSL-NELSNVSSflLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRL 491
Cdd:PLN00113   201 --VGQIPRELGQMKSLKWIYLGYNNLSGEIpYEIGGLTS--LNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPI 276
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  492 NLTVFkqlknitrlelssnslsvetestdsssfpqmttlklascnlrmfpgflkNQSKLNSLDLSHNDLQGEIPLWIWGL 571
Cdd:PLN00113   277 PPSIF-------------------------------------------------SLQKLISLDLSDNSLSGEIPELVIQL 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  572 ENLNQLNLscnslvgfegppknlssslylldlhsnkfegplsffpssaayldFSNNsfssaiipaigqylsstvffslsr 651
Cdd:PLN00113   308 QNLEILHL--------------------------------------------FSNN------------------------ 319
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  652 nrIQGNIPESICDSKSLQVLDLSNNDLSGMFPQCLTEKNdNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRV 731
Cdd:PLN00113   320 --FTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHN-NLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEI 396
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  732 PKSLSNCRYLEVLDLGKNSIDDIFPCSLKSISTLRVLVLRSNKFHGKFgcQDTNGTWKSLQIVDISRNYFNGSISgkcie 811
Cdd:PLN00113   397 PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRI--NSRKWDMPSLQMLSLARNKFFGGLP----- 469
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  812 kwkamvdeEDFSKSRANHLRFNFFKFSAVNYQDTVTitskgldveltkiLTVFTSIDFSCNLFNGHIPAEIGELKALYLL 891
Cdd:PLN00113   470 --------DSFGSKRLENLDLSRNQFSGAVPRKLGS-------------LSELMQLKLSENKLSGEIPDELSSCKKLVSL 528
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  892 NFSHNYLSGEIPSSIGNLSQLGSLDLSRNRLTGQIPQQLAGLSFLSVLNLSYNLLVGMIPIGSQFQTFSEDSFIGNEGLC 971
Cdd:PLN00113   529 DLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLC 608

                   .
gi 1775891392  972 G 972
Cdd:PLN00113   609 G 609
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
16-622 6.47e-57

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 214.33  E-value: 6.47e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   16 FLFLSVGISLVsgrcpdDQHSLLLQLKNDLvynSSFSKKLVHWNERVDYCNWNGVNCTDGC-VTDLDLSEELILGGIdnS 94
Cdd:PLN00113    18 FLFLNFSMLHA------EELELLLSFKSSI---NDPLKYLSNWNSSADVCLWQGITCNNSSrVVSIDLSGKNISGKI--S 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   95 SSLFSLRFLRTLNLGFNRFNSLMPSG-FNRLSNLSVLNMSNSGFNGQIPIeiSNLTGLVSLDLTSSplfqfpTLKLENPN 173
Cdd:PLN00113    87 SAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNN------MLSGEIPN 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  174 lrtfvqnlsNLGelilngvdlsaqgrewckalssSLLNLTVLSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPVPDN 253
Cdd:PLN00113   159 ---------DIG----------------------SFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRE 207
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  254 YADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLLQGSLPDFPSSRPLQTLVLQGTKFSGTLPESIGYFENLT 333
Cdd:PLN00113   208 LGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLI 287
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLA------------------------SCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNR 388
Cdd:PLN00113   288 SLDLSdnslsgeipelviqlqnleilhlfSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPkNLGKHNNLTVLDLSTNN 367
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  389 LNGSLLSTKWEElPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSGSL-NELSNVSsfLLDTLDLESNRLEGPF 467
Cdd:PLN00113   368 LTGEIPEGLCSS-GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELpSEFTKLP--LVYFLDISNNNLQGRI 444
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  468 PMSFLELQGLKILSLSFNNFTGrlNLTVFKQLKNITRLELSSNSLSvETESTDSSSFPQMTTLKLASCNLR-MFPGFLKN 546
Cdd:PLN00113   445 NSRKWDMPSLQMLSLARNKFFG--GLPDSFGSKRLENLDLSRNQFS-GAVPRKLGSLSELMQLKLSENKLSgEIPDELSS 521
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1775891392  547 QSKLNSLDLSHNDLQGEIPLWIWGLENLNQLNLSCNSLVGFEGPPKNLSSSLYLLDLHSNKFEGPLsffPSSAAYL 622
Cdd:PLN00113   522 CKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSL---PSTGAFL 594
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
256-972 2.32e-63

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 233.97  E-value: 2.32e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  256 DFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLlQGSLPD--FPSSRPLQTLVLQGTKFSGTLPEsiGYFENLT 333
Cdd:PLN00113    67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQL-SGPIPDdiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLE 143
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNRLngsllstkweelpnlvnldlrnn 412
Cdd:PLN00113   144 TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPnSLTNLTSLEFLTLASNQL----------------------- 200
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  413 siTGNVPSSLFNLQTIRKIQLNYNLFSGSL-NELSNVSSflLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRL 491
Cdd:PLN00113   201 --VGQIPRELGQMKSLKWIYLGYNNLSGEIpYEIGGLTS--LNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPI 276
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  492 NLTVFkqlknitrlelssnslsvetestdsssfpqmttlklascnlrmfpgflkNQSKLNSLDLSHNDLQGEIPLWIWGL 571
Cdd:PLN00113   277 PPSIF-------------------------------------------------SLQKLISLDLSDNSLSGEIPELVIQL 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  572 ENLNQLNLscnslvgfegppknlssslylldlhsnkfegplsffpssaayldFSNNsfssaiipaigqylsstvffslsr 651
Cdd:PLN00113   308 QNLEILHL--------------------------------------------FSNN------------------------ 319
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  652 nrIQGNIPESICDSKSLQVLDLSNNDLSGMFPQCLTEKNdNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRV 731
Cdd:PLN00113   320 --FTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHN-NLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEI 396
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  732 PKSLSNCRYLEVLDLGKNSIDDIFPCSLKSISTLRVLVLRSNKFHGKFgcQDTNGTWKSLQIVDISRNYFNGSISgkcie 811
Cdd:PLN00113   397 PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRI--NSRKWDMPSLQMLSLARNKFFGGLP----- 469
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  812 kwkamvdeEDFSKSRANHLRFNFFKFSAVNYQDTVTitskgldveltkiLTVFTSIDFSCNLFNGHIPAEIGELKALYLL 891
Cdd:PLN00113   470 --------DSFGSKRLENLDLSRNQFSGAVPRKLGS-------------LSELMQLKLSENKLSGEIPDELSSCKKLVSL 528
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  892 NFSHNYLSGEIPSSIGNLSQLGSLDLSRNRLTGQIPQQLAGLSFLSVLNLSYNLLVGMIPIGSQFQTFSEDSFIGNEGLC 971
Cdd:PLN00113   529 DLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLC 608

                   .
gi 1775891392  972 G 972
Cdd:PLN00113   609 G 609
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
16-622 6.47e-57

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 214.33  E-value: 6.47e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   16 FLFLSVGISLVsgrcpdDQHSLLLQLKNDLvynSSFSKKLVHWNERVDYCNWNGVNCTDGC-VTDLDLSEELILGGIdnS 94
Cdd:PLN00113    18 FLFLNFSMLHA------EELELLLSFKSSI---NDPLKYLSNWNSSADVCLWQGITCNNSSrVVSIDLSGKNISGKI--S 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   95 SSLFSLRFLRTLNLGFNRFNSLMPSG-FNRLSNLSVLNMSNSGFNGQIPIeiSNLTGLVSLDLTSSplfqfpTLKLENPN 173
Cdd:PLN00113    87 SAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNN------MLSGEIPN 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  174 lrtfvqnlsNLGelilngvdlsaqgrewckalssSLLNLTVLSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPVPDN 253
Cdd:PLN00113   159 ---------DIG----------------------SFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRE 207
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  254 YADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLLQGSLPDFPSSRPLQTLVLQGTKFSGTLPESIGYFENLT 333
Cdd:PLN00113   208 LGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLI 287
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLA------------------------SCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNR 388
Cdd:PLN00113   288 SLDLSdnslsgeipelviqlqnleilhlfSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPkNLGKHNNLTVLDLSTNN 367
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  389 LNGSLLSTKWEElPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSGSL-NELSNVSsfLLDTLDLESNRLEGPF 467
Cdd:PLN00113   368 LTGEIPEGLCSS-GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELpSEFTKLP--LVYFLDISNNNLQGRI 444
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  468 PMSFLELQGLKILSLSFNNFTGrlNLTVFKQLKNITRLELSSNSLSvETESTDSSSFPQMTTLKLASCNLR-MFPGFLKN 546
Cdd:PLN00113   445 NSRKWDMPSLQMLSLARNKFFG--GLPDSFGSKRLENLDLSRNQFS-GAVPRKLGSLSELMQLKLSENKLSgEIPDELSS 521
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1775891392  547 QSKLNSLDLSHNDLQGEIPLWIWGLENLNQLNLSCNSLVGFEGPPKNLSSSLYLLDLHSNKFEGPLsffPSSAAYL 622
Cdd:PLN00113   522 CKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSL---PSTGAFL 594
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
122-542 2.59e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 106.94  E-value: 2.59e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  122 NRLSNLSVLNMSNSGFNGQIPIEISNLTGLVSLDLTSSPLFQFPTLKLENPNLRTFVQNLSNLGELILNGVDLSAQGREW 201
Cdd:COG4886      8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  202 CKALSSSLLNLTVLSLSGCalsgpldSSLAKLRYLSDIRLDNNIFSSpVPDNYADFPTLTSLHLGSSNLSgEFPQSIFQV 281
Cdd:COG4886     88 GLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DLPEPLGNL 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  282 STLQTLDLSNNKLlqGSLPDFPSSRP-LQTLVLQGTKFSgTLPESIGYFENLTKLDLASCNFGgSIPNSILNLTQLTYLD 360
Cdd:COG4886    159 TNLKSLDLSNNQL--TDLPEELGNLTnLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLD 234
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  361 LSSNKFVgPVPSFSQLKNLTVLNLAHNRLNGSllsTKWEELPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSG 440
Cdd:COG4886    235 LSNNQLT-DLPELGNLTNLEELDLSNNQLTDL---PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNL 310
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  441 SLNELSNVSSFLLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRLNLTVFKQLKNITRLELSSNSLSVETESTD 520
Cdd:COG4886    311 LELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
                          410       420
                   ....*....|....*....|..
gi 1775891392  521 SSSFPQMTTLKLASCNLRMFPG 542
Cdd:COG4886    391 LLLLTTTAGVLLLTLALLDAVN 412
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
36-448 1.93e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.98  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   36 SLLLQLKNDLVYNSSFSKKLVHWNERVDYCNWNGVNCTDGCVTDLDLSEELILGGIDNSSSLFSLRFLRTLNLGFNRfns 115
Cdd:COG4886     31 LLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE--- 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  116 lmpsGFNRLSNLSVLNMSNSGFNgQIPIEISNLTGLVSLDLTSSPLFQFPTlklenpnlrtFVQNLSNLGELILNGVDLS 195
Cdd:COG4886    108 ----ELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTDLPE----------PLGNLTNLKSLDLSNNQLT 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  196 AQGREwckalSSSLLNLTVLSLSGCALSgPLDSSLAKLRYLSDIRLDNNIFSSpVPDNYADFPTLTSLHLGSSNLSgEFP 275
Cdd:COG4886    173 DLPEE-----LGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTD-LPEPLANLTNLETLDLSNNQLT-DLP 244
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  276 qSIFQVSTLQTLDLSNNKLlqGSLPDFPSSRPLQTLVLQGTKFSGTLPESIGYFENLTKLDLASCNFGGSIPNSILNLTQ 355
Cdd:COG4886    245 -ELGNLTNLEELDLSNNQL--TDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLT 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  356 LTYLDLSSNKFVGPVPSFSQLKNLTVLNLAHNRLNGSLLSTKWEELPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNY 435
Cdd:COG4886    322 TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVL 401
                          410
                   ....*....|...
gi 1775891392  436 NLFSGSLNELSNV 448
Cdd:COG4886    402 LLTLALLDAVNTE 414
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
353-532 2.92e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 55.56  E-value: 2.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  353 LTQLTYLDLSsNKFVGPVPSFSQLKNLTVLNLAHNRLngsllsTKWEEL---PNLVNLDLRNNSIT--GNVpSSLFNLQt 427
Cdd:cd21340      1 LKRITHLYLN-DKNITKIDNLSLCKNLKVLYLYDNKI------TKIENLeflTNLTHLYLQNNQIEkiENL-ENLVNLK- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  428 irKIQLNYNLFSgSLNELSNVSSflLDTLDLESNRLEGPFPMSFLE------LQGLKILSLSFNNFTgrlNLTVFKQLKN 501
Cdd:cd21340     72 --KLYLGGNRIS-VVEGLENLTN--LEELHIENQRLPPGEKLTFDPrslaalSNSLRVLNISGNNID---SLEPLAPLRN 143
                          170       180       190
                   ....*....|....*....|....*....|..
gi 1775891392  502 ITRLELSSNSLSVETESTDS-SSFPQMTTLKL 532
Cdd:cd21340    144 LEQLDASNNQISDLEELLDLlSSWPSLRELDL 175
LRR_8 pfam13855
Leucine rich repeat;
667-727 5.66e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.13  E-value: 5.66e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  667 SLQVLDLSNNDLSGMFPQCLTeKNDNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNI 727
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGAFK-GLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
103-161 4.33e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 4.33e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1775891392  103 LRTLNLGFNRFNSLMPSGFNRLSNLSVLNMSNSGFNGQIPIEISNLTGLVSLDLTSSPL 161
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
256-972 2.32e-63

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 233.97  E-value: 2.32e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  256 DFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLlQGSLPD--FPSSRPLQTLVLQGTKFSGTLPEsiGYFENLT 333
Cdd:PLN00113    67 NSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQL-SGPIPDdiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLE 143
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNRLngsllstkweelpnlvnldlrnn 412
Cdd:PLN00113   144 TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPnSLTNLTSLEFLTLASNQL----------------------- 200
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  413 siTGNVPSSLFNLQTIRKIQLNYNLFSGSL-NELSNVSSflLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRL 491
Cdd:PLN00113   201 --VGQIPRELGQMKSLKWIYLGYNNLSGEIpYEIGGLTS--LNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPI 276
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  492 NLTVFkqlknitrlelssnslsvetestdsssfpqmttlklascnlrmfpgflkNQSKLNSLDLSHNDLQGEIPLWIWGL 571
Cdd:PLN00113   277 PPSIF-------------------------------------------------SLQKLISLDLSDNSLSGEIPELVIQL 307
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  572 ENLNQLNLscnslvgfegppknlssslylldlhsnkfegplsffpssaayldFSNNsfssaiipaigqylsstvffslsr 651
Cdd:PLN00113   308 QNLEILHL--------------------------------------------FSNN------------------------ 319
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  652 nrIQGNIPESICDSKSLQVLDLSNNDLSGMFPQCLTEKNdNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRV 731
Cdd:PLN00113   320 --FTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHN-NLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEI 396
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  732 PKSLSNCRYLEVLDLGKNSIDDIFPCSLKSISTLRVLVLRSNKFHGKFgcQDTNGTWKSLQIVDISRNYFNGSISgkcie 811
Cdd:PLN00113   397 PKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRI--NSRKWDMPSLQMLSLARNKFFGGLP----- 469
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  812 kwkamvdeEDFSKSRANHLRFNFFKFSAVNYQDTVTitskgldveltkiLTVFTSIDFSCNLFNGHIPAEIGELKALYLL 891
Cdd:PLN00113   470 --------DSFGSKRLENLDLSRNQFSGAVPRKLGS-------------LSELMQLKLSENKLSGEIPDELSSCKKLVSL 528
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  892 NFSHNYLSGEIPSSIGNLSQLGSLDLSRNRLTGQIPQQLAGLSFLSVLNLSYNLLVGMIPIGSQFQTFSEDSFIGNEGLC 971
Cdd:PLN00113   529 DLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLC 608

                   .
gi 1775891392  972 G 972
Cdd:PLN00113   609 G 609
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
201-805 4.17e-62

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 230.12  E-value: 4.17e-62
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  201 WCKALSSSLLNLTVLSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPVPDN-YADFPTLTSLHLGSSNLSGEFPQSif 279
Cdd:PLN00113    60 WQGITCNNSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPRG-- 137
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  280 QVSTLQTLDLSNNKllqgslpdfpssrplqtlvlqgtkFSGTLPESIGYFENLTKLDLASCNFGGSIPNSILNLTQLTYL 359
Cdd:PLN00113   138 SIPNLETLDLSNNM------------------------LSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFL 193
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  360 DLSSNKFVGPVPS-FSQLKNLTVLNLAHNRLNGSLlSTKWEELPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLF 438
Cdd:PLN00113   194 TLASNQLVGQIPReLGQMKSLKWIYLGYNNLSGEI-PYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKL 272
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  439 SGSLNElSNVSSFLLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRLNLTVfKQLKNITRLELSSNSLSVEtes 518
Cdd:PLN00113   273 SGPIPP-SIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVAL-TSLPRLQVLQLWSNKFSGE--- 347
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  519 tdsssfpqmttlklascnlrmFPGFLKNQSKLNSLDLSHNDLQGEIPLWIWGLENLNQLNLSCNSLVGfEGPPKNLSSsl 598
Cdd:PLN00113   348 ---------------------IPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEG-EIPKSLGAC-- 403
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  599 ylldlhsnkfegplsffpSSAAYLDFSNNSFSSAIiPAIGQYLSSTVFFSLSRNRIQGNIPESICDSKSLQVLDLSNNDL 678
Cdd:PLN00113   404 ------------------RSLRRVRLQDNSFSGEL-PSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKF 464
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  679 SGMFPQclTEKNDNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRVPKSLSNCRYLEVLDLGKNSIDDIFPCS 758
Cdd:PLN00113   465 FGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPAS 542
                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1775891392  759 LKSISTLRVLVLRSNKFHGKFgcqDTN-GTWKSLQIVDISRNYFNGSI 805
Cdd:PLN00113   543 FSEMPVLSQLDLSQNQLSGEI---PKNlGNVESLVQVNISHNHLHGSL 587
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
16-622 6.47e-57

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 214.33  E-value: 6.47e-57
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   16 FLFLSVGISLVsgrcpdDQHSLLLQLKNDLvynSSFSKKLVHWNERVDYCNWNGVNCTDGC-VTDLDLSEELILGGIdnS 94
Cdd:PLN00113    18 FLFLNFSMLHA------EELELLLSFKSSI---NDPLKYLSNWNSSADVCLWQGITCNNSSrVVSIDLSGKNISGKI--S 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   95 SSLFSLRFLRTLNLGFNRFNSLMPSG-FNRLSNLSVLNMSNSGFNGQIPIeiSNLTGLVSLDLTSSplfqfpTLKLENPN 173
Cdd:PLN00113    87 SAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNN------MLSGEIPN 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  174 lrtfvqnlsNLGelilngvdlsaqgrewckalssSLLNLTVLSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPVPDN 253
Cdd:PLN00113   159 ---------DIG----------------------SFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRE 207
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  254 YADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLLQGSLPDFPSSRPLQTLVLQGTKFSGTLPESIGYFENLT 333
Cdd:PLN00113   208 LGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLI 287
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLA------------------------SCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNR 388
Cdd:PLN00113   288 SLDLSdnslsgeipelviqlqnleilhlfSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPkNLGKHNNLTVLDLSTNN 367
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  389 LNGSLLSTKWEElPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSGSL-NELSNVSsfLLDTLDLESNRLEGPF 467
Cdd:PLN00113   368 LTGEIPEGLCSS-GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELpSEFTKLP--LVYFLDISNNNLQGRI 444
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  468 PMSFLELQGLKILSLSFNNFTGrlNLTVFKQLKNITRLELSSNSLSvETESTDSSSFPQMTTLKLASCNLR-MFPGFLKN 546
Cdd:PLN00113   445 NSRKWDMPSLQMLSLARNKFFG--GLPDSFGSKRLENLDLSRNQFS-GAVPRKLGSLSELMQLKLSENKLSgEIPDELSS 521
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1775891392  547 QSKLNSLDLSHNDLQGEIPLWIWGLENLNQLNLSCNSLVGFEGPPKNLSSSLYLLDLHSNKFEGPLsffPSSAAYL 622
Cdd:PLN00113   522 CKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSL---PSTGAFL 594
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
122-542 2.59e-24

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 106.94  E-value: 2.59e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  122 NRLSNLSVLNMSNSGFNGQIPIEISNLTGLVSLDLTSSPLFQFPTLKLENPNLRTFVQNLSNLGELILNGVDLSAQGREW 201
Cdd:COG4886      8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  202 CKALSSSLLNLTVLSLSGCalsgpldSSLAKLRYLSDIRLDNNIFSSpVPDNYADFPTLTSLHLGSSNLSgEFPQSIFQV 281
Cdd:COG4886     88 GLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTD-LPEELANLTNLKELDLSNNQLT-DLPEPLGNL 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  282 STLQTLDLSNNKLlqGSLPDFPSSRP-LQTLVLQGTKFSgTLPESIGYFENLTKLDLASCNFGgSIPNSILNLTQLTYLD 360
Cdd:COG4886    159 TNLKSLDLSNNQL--TDLPEELGNLTnLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLD 234
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  361 LSSNKFVgPVPSFSQLKNLTVLNLAHNRLNGSllsTKWEELPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSG 440
Cdd:COG4886    235 LSNNQLT-DLPELGNLTNLEELDLSNNQLTDL---PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNL 310
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  441 SLNELSNVSSFLLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRLNLTVFKQLKNITRLELSSNSLSVETESTD 520
Cdd:COG4886    311 LELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLL 390
                          410       420
                   ....*....|....*....|..
gi 1775891392  521 SSSFPQMTTLKLASCNLRMFPG 542
Cdd:COG4886    391 LLLLTTTAGVLLLTLALLDAVN 412
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
171-576 1.04e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 99.24  E-value: 1.04e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  171 NPNLRTFVQNLSNLGELILNGVDLSAQGREWCKALSSSLLNLTVLSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPV 250
Cdd:COG4886      2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  251 PDNYADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKL--LQGSLPDFPSsrpLQTLVLQGTKFSgTLPESIGY 328
Cdd:COG4886     82 LSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLtdLPEELANLTN---LKELDLSNNQLT-DLPEPLGN 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  329 FENLTKLDLASCNFGgSIPNSILNLTQLTYLDLSSNKFVGPVPSFSQLKNLTVLNLAHNRLngSLLSTKWEELPNLVNLD 408
Cdd:COG4886    158 LTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQL--TDLPEPLANLTNLETLD 234
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  409 LRNNSITgNVPSsLFNLQTIRKIQLNYNLFSgSLNELSNVSSflLDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFT 488
Cdd:COG4886    235 LSNNQLT-DLPE-LGNLTNLEELDLSNNQLT-DLPPLANLTN--LKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLN 309
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  489 GRLNLTVFKQLKNITRLELSSNSLSVETESTDSSSFPQMTTLKLASCNLRMFPGFLKNQSKLNSLDLSHNDLQGEIPLWI 568
Cdd:COG4886    310 LLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTL 389

                   ....*...
gi 1775891392  569 WGLENLNQ 576
Cdd:COG4886    390 LLLLLTTT 397
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
140-564 1.77e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 98.47  E-value: 1.77e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  140 QIPIEISNLTGLVSLDLTSSPLFQFPTLKLENPNLRTFVQNLSNLGELILNGVDLSAQGREWCKALSSSLLNLTVLSLSG 219
Cdd:COG4886      2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLL 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  220 CALSGPLDSSLAKLRYLSDIRLDNNIFSSpvpdnyaDFPTLTSLHLGSSNLSgEFPQSIFQVSTLQTLDLSNNKL--LQG 297
Cdd:COG4886     82 LSLLLLGLTDLGDLTNLTELDLSGNEELS-------NLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLtdLPE 153
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  298 SLPDFPSsrpLQTLVLQGTKFSgTLPESIGYFENLTKLDLASCNFGgSIPNSILNLTQLTYLDLSSNKFVGPVPSFSQLK 377
Cdd:COG4886    154 PLGNLTN---LKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT 228
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  378 NLTVLNLAHNRLNgSLLStkWEELPNLVNLDLRNNSITGnvPSSLFNLQTIRKIQLNYNLFSG----SLNELSNVSSFLL 453
Cdd:COG4886    229 NLETLDLSNNQLT-DLPE--LGNLTNLEELDLSNNQLTD--LPPLANLTNLKTLDLSNNQLTDlklkELELLLGLNSLLL 303
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  454 DTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRLNLTVFKQLKNITRLELSSNSLSVETESTDSSSFPQMTTLKLA 533
Cdd:COG4886    304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383
                          410       420       430
                   ....*....|....*....|....*....|.
gi 1775891392  534 SCNLRMFPGFLKNQSKLNSLDLSHNDLQGEI 564
Cdd:COG4886    384 LLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
235-579 4.39e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.23  E-value: 4.39e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  235 YLSDIRLDNNIFSSPVPDNYADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLLQGSLPDFPSSRPLQTLVLQ 314
Cdd:COG4886      1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  315 GTKFSGTLPESIGYFENLTKLDLascnfggSIPNSILNLTQLTYLDLSSNKFVGPVPSFSQLKNLTVLNLAHNRLngSLL 394
Cdd:COG4886     81 LLSLLLLGLTDLGDLTNLTELDL-------SGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL--TDL 151
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  395 STKWEELPNLVNLDLRNNSITgNVPSSLFNLQTIRKIQLNYNLFSGSLNELSNVSSflLDTLDLESNRLEgPFPMSFLEL 474
Cdd:COG4886    152 PEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQITDLPEPLGNLTN--LEELDLSGNQLT-DLPEPLANL 227
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  475 QGLKILSLSFNNFTgrlNLTVFKQLKNITRLELSSNSLsveTESTDSSSFPQMTTLKLASCNLR-MFPGFLKNQSKLNSL 553
Cdd:COG4886    228 TNLETLDLSNNQLT---DLPELGNLTNLEELDLSNNQL---TDLPPLANLTNLKTLDLSNNQLTdLKLKELELLLGLNSL 301
                          330       340
                   ....*....|....*....|....*.
gi 1775891392  554 DLSHNDLQGEIPLWIWGLENLNQLNL 579
Cdd:COG4886    302 LLLLLLLNLLELLILLLLLTTLLLLL 327
PLN03150 PLN03150
hypothetical protein; Provisional
876-1016 1.47e-16

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 84.87  E-value: 1.47e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  876 GHIPAEIGELKALYLLNFSHNYLSGEIPSSIGNLSQLGSLDLSRNRLTGQIPQQLAGLSFLSVLNLSYNLLVGMIP--IG 953
Cdd:PLN03150   432 GFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPaaLG 511
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1775891392  954 SQFQTFSEDSFIGNEGLCGYPLPNKCKtaihPTSDTSNKksdsvadadwqfvfIGVGFGVGAA 1016
Cdd:PLN03150   512 GRLLHRASFNFTDNAGLCGIPGLRACG----PHLSVGAK--------------IGIAFGVSVA 556
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
36-448 1.93e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 79.98  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   36 SLLLQLKNDLVYNSSFSKKLVHWNERVDYCNWNGVNCTDGCVTDLDLSEELILGGIDNSSSLFSLRFLRTLNLGFNRfns 115
Cdd:COG4886     31 LLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE--- 107
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  116 lmpsGFNRLSNLSVLNMSNSGFNgQIPIEISNLTGLVSLDLTSSPLFQFPTlklenpnlrtFVQNLSNLGELILNGVDLS 195
Cdd:COG4886    108 ----ELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTDLPE----------PLGNLTNLKSLDLSNNQLT 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  196 AQGREwckalSSSLLNLTVLSLSGCALSgPLDSSLAKLRYLSDIRLDNNIFSSpVPDNYADFPTLTSLHLGSSNLSgEFP 275
Cdd:COG4886    173 DLPEE-----LGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTD-LPEPLANLTNLETLDLSNNQLT-DLP 244
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  276 qSIFQVSTLQTLDLSNNKLlqGSLPDFPSSRPLQTLVLQGTKFSGTLPESIGYFENLTKLDLASCNFGGSIPNSILNLTQ 355
Cdd:COG4886    245 -ELGNLTNLEELDLSNNQL--TDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLT 321
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  356 LTYLDLSSNKFVGPVPSFSQLKNLTVLNLAHNRLNGSLLSTKWEELPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNY 435
Cdd:COG4886    322 TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVL 401
                          410
                   ....*....|...
gi 1775891392  436 NLFSGSLNELSNV 448
Cdd:COG4886    402 LLTLALLDAVNTE 414
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
405-835 9.72e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 77.67  E-value: 9.72e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  405 VNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSGSLNELSNVSSFLLDTLDLESNRLEGPFPMSFLELQGLKILSLSF 484
Cdd:COG4886      1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  485 NNFTGRLNLTVFKQLKNITRLELSSNslsvetesTDSSSFPQMTTLKLASCNLRMFPGFLKNQSKLNSLDLSHNDLQgEI 564
Cdd:COG4886     81 LLSLLLLGLTDLGDLTNLTELDLSGN--------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLT-DL 151
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  565 PLWIWGLENLNQLNLSCNSLVGfegppknlssslylldlhsnkfegplsffpssaayldfsnnsfssaiIPAIGQYLSST 644
Cdd:COG4886    152 PEPLGNLTNLKSLDLSNNQLTD-----------------------------------------------LPEELGNLTNL 184
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  645 VFFSLSRNRIQgNIPESICDSKSLQVLDLSNNDLSGMfPQCLTeKNDNLVVLNLRENALNgSIPNaFPANCSLRTLDLSG 724
Cdd:COG4886    185 KELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTDL-PEPLA-NLTNLETLDLSNNQLT-DLPE-LGNLTNLEELDLSN 259
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  725 NNIEGrvPKSLSNCRYLEVLDLGKNSIDDIFPCSLKSISTLRVLVLRSNKFHGKFGCQDTNGTWKSLQIVDISRNYFNGS 804
Cdd:COG4886    260 NQLTD--LPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTL 337
                          410       420       430
                   ....*....|....*....|....*....|.
gi 1775891392  805 ISGKCIEKWKAMVDEEDFSKSRANHLRFNFF 835
Cdd:COG4886    338 TTLALSLSLLALLTLLLLLNLLSLLLTLLLT 368
PLN03150 PLN03150
hypothetical protein; Provisional
696-778 4.70e-11

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 66.76  E-value: 4.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  696 LNLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRVPKSLSNCRYLEVLDLGKNSIDDIFPCSLKSISTLRVLVLRSNKF 775
Cdd:PLN03150   423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                   ...
gi 1775891392  776 HGK 778
Cdd:PLN03150   503 SGR 505
PLN03150 PLN03150
hypothetical protein; Provisional
648-735 8.75e-10

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 62.91  E-value: 8.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  648 SLSRNRIQGNIPESICDSKSLQVLDLSNNDLSGMFPQCLTEKNdNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNI 727
Cdd:PLN03150   424 GLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSIT-SLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                   ....*...
gi 1775891392  728 EGRVPKSL 735
Cdd:PLN03150   503 SGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
291-372 3.19e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 60.99  E-value: 3.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  291 NNKLLQGSLP-DFPSSRPLQTLVLQGTKFSGTLPESIGYFENLTKLDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGP 369
Cdd:PLN03150   426 DNQGLRGFIPnDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGR 505

                   ...
gi 1775891392  370 VPS 372
Cdd:PLN03150   506 VPA 508
PLN03150 PLN03150
hypothetical protein; Provisional
335-422 8.91e-09

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 59.44  E-value: 8.91e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  335 LDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNRLNGSLLSTkWEELPNLVNLDLRNNS 413
Cdd:PLN03150   423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPpSLGSITSLEVLDLSYNSFNGSIPES-LGQLTSLRILNLNGNS 501

                   ....*....
gi 1775891392  414 ITGNVPSSL 422
Cdd:PLN03150   502 LSGRVPAAL 510
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
654-946 1.20e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 58.79  E-value: 1.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  654 IQGNIPESICDSKSLQVLDLSNNDLSGmfpqclteKNDNLVVLNLRENALNgSIPNAFPANCSLRTLDLSGNNIEgRVPK 733
Cdd:COG4886     84 LLLLGLTDLGDLTNLTELDLSGNEELS--------NLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLT-DLPE 153
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  734 SLSNCRYLEVLDLGKNSIDDIfPCSLKSISTLRVLVLRSNKfhgkfgcqdtngtwkslqivdisrnyfngsisgkciekw 813
Cdd:COG4886    154 PLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQ--------------------------------------- 193
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  814 kamvdeedfsksranhlrfnffkfsavnyqdtvtITSkgldveltkiltvftsidfscnlfnghIPAEIGELKALYLLNF 893
Cdd:COG4886    194 ----------------------------------ITD---------------------------LPEPLGNLTNLEELDL 212
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1775891392  894 SHNYLSgEIPSSIGNLSQLGSLDLSRNRLTgQIPqQLAGLSFLSVLNLSYNLL 946
Cdd:COG4886    213 SGNQLT-DLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQL 262
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
353-532 2.92e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 55.56  E-value: 2.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  353 LTQLTYLDLSsNKFVGPVPSFSQLKNLTVLNLAHNRLngsllsTKWEEL---PNLVNLDLRNNSIT--GNVpSSLFNLQt 427
Cdd:cd21340      1 LKRITHLYLN-DKNITKIDNLSLCKNLKVLYLYDNKI------TKIENLeflTNLTHLYLQNNQIEkiENL-ENLVNLK- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  428 irKIQLNYNLFSgSLNELSNVSSflLDTLDLESNRLEGPFPMSFLE------LQGLKILSLSFNNFTgrlNLTVFKQLKN 501
Cdd:cd21340     72 --KLYLGGNRIS-VVEGLENLTN--LEELHIENQRLPPGEKLTFDPrslaalSNSLRVLNISGNNID---SLEPLAPLRN 143
                          170       180       190
                   ....*....|....*....|....*....|..
gi 1775891392  502 ITRLELSSNSLSVETESTDS-SSFPQMTTLKL 532
Cdd:cd21340    144 LEQLDASNNQISDLEELLDLlSSWPSLRELDL 175
PLN03150 PLN03150
hypothetical protein; Provisional
671-759 2.04e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.21  E-value: 2.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  671 LDLSNNDLSGMFPQCLTeKNDNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRVPKSLSNCRYLEVLDLGKNS 750
Cdd:PLN03150   423 LGLDNQGLRGFIPNDIS-KLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501

                   ....*....
gi 1775891392  751 IDDIFPCSL 759
Cdd:PLN03150   502 LSGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
891-951 2.06e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.21  E-value: 2.06e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  891 LNFSHNYLSGEIPSSIGNLSQLGSLDLSRNRLTGQIPQQLAGLSFLSVLNLSYNLLVGMIP 951
Cdd:PLN03150   423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIP 483
PLN03150 PLN03150
hypothetical protein; Provisional
382-488 2.13e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 55.21  E-value: 2.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  382 LNLAHNRLNGSLLSTkWEELPNLVNLDLRNNSITGNVPSSLFNLQTIRKIQLNYNLFSGSLNE-LSNVSSflLDTLDLES 460
Cdd:PLN03150   423 LGLDNQGLRGFIPND-ISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPEsLGQLTS--LRILNLNG 499
                           90       100
                   ....*....|....*....|....*...
gi 1775891392  461 NRLEGPFPMSfleLQGLKILSLSFnNFT 488
Cdd:PLN03150   500 NSLSGRVPAA---LGGRLLHRASF-NFT 523
PLN03150 PLN03150
hypothetical protein; Provisional
861-907 4.01e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 54.05  E-value: 4.01e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 1775891392  861 LTVFTSIDFSCNLFNGHIPAEIGELKALYLLNFSHNYLSGEIPSSIG 907
Cdd:PLN03150   465 ITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
PLN03150 PLN03150
hypothetical protein; Provisional
215-308 4.33e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 54.05  E-value: 4.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  215 LSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPVPDNYADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKl 294
Cdd:PLN03150   423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS- 501
                           90
                   ....*....|....
gi 1775891392  295 LQGSLPDFPSSRPL 308
Cdd:PLN03150   502 LSGRVPAALGGRLL 515
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
258-463 5.10e-07

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 53.64  E-value: 5.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  258 PTLTSLHLGSSNLSGEFPQSIFQV----STLQTLDLSNNKLLQGSLPdfpssrplqtlvlqgtkfsgTLPESIGYFENLT 333
Cdd:COG5238    208 TTVTTLWLKRNPIGDEGAEILAEAlkgnKSLTTLDLSNNQIGDEGVI--------------------ALAEALKNNTTVE 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  334 KLDLaSCNFGG-----SIPNSILNLTQLTYLDLSSNKFVGP-----VPSFSQLKNLTVLNLAHNRLNGS---LLSTKWEE 400
Cdd:COG5238    268 TLYL-SGNQIGaegaiALAKALQGNTTLTSLDLSVNRIGDEgaialAEGLQGNKTLHTLNLAYNGIGAQgaiALAKALQE 346
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  401 LPNLVNLDLRNNSITGN----VPSSLFNLQTIRKIQLNYNLFSG----SLNELSNVSSflLDTLDLESNRL 463
Cdd:COG5238    347 NTTLHSLDLSDNQIGDEgaiaLAKYLEGNTTLRELNLGKNNIGKqgaeALIDALQTNR--LHTLILDGNLI 415
PLN03150 PLN03150
hypothetical protein; Provisional
235-327 5.14e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 54.05  E-value: 5.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  235 YLSDIRLDNNIFSSPVPDNYADFPTLTSLHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKlLQGSLPD-FPSSRPLQTLVL 313
Cdd:PLN03150   419 FIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNS-FNGSIPEsLGQLTSLRILNL 497
                           90
                   ....*....|....
gi 1775891392  314 QGTKFSGTLPESIG 327
Cdd:PLN03150   498 NGNSLSGRVPAALG 511
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
500-838 1.05e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.16  E-value: 1.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  500 KNITRLELSSNSLSvetesTDSSSFP-QMTTLKLASCNLRMFPGFLK--------NQSKLNSL-----------DLSHND 559
Cdd:PRK15370   178 NNKTELRLKILGLT-----TIPACIPeQITTLILDNNELKSLPENLQgniktlyaNSNQLTSIpatlpdtiqemELSINR 252
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  560 LQgEIPLWIwgLENLNQLNLSCNSLVGFegpPKNLSSSLYLLDLHSNKFEGPLSFFPSSAAYLDFSNNSFSsaiipaigq 639
Cdd:PRK15370   253 IT-ELPERL--PSALQSLDLFHNKISCL---PENLPEELRYLSVYDNSIRTLPAHLPSGITHLNVQSNSLT--------- 317
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  640 YLSSTVFFSLSRNRIQGN----IPESIcdSKSLQVLDLSNNDLSgMFPQCLTEkndNLVVLNLRENALNgSIPNAFPAnc 715
Cdd:PRK15370   318 ALPETLPPGLKTLEAGENaltsLPASL--PPELQVLDVSKNQIT-VLPETLPP---TITTLDVSRNALT-NLPENLPA-- 388
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  716 SLRTLDLSGNNIeGRVPKSLSNcrYLEVLDLGKNSIDDIFPCSLKSISTLRVLvLRSNKFHGK---FGCQDtngtwksLQ 792
Cdd:PRK15370   389 ALQIMQASRNNL-VRLPESLPH--FRGEGPQPTRIIVEYNPFSERTIQNMQRL-MSSVGYQGPrvlFAMGD-------FS 457
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1775891392  793 IVDISRNYFngsisgKCIEKWKAMVDEEDFSKSRANHLRFNFFKFS 838
Cdd:PRK15370   458 IVRVTRPLH------QAVQGWLTNLEEEDVNQWRAFETEVNAAAFS 497
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
647-783 1.11e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.97  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  647 FSLSRNRIQGNIPESICD----SKSLQVLDLSNNDLSGMFPQCLTE---KNDNLVVLNLRENALN----GSIPNAFPANC 715
Cdd:cd00116    142 LVLGRNRLEGASCEALAKalraNRDLKELNLANNGIGDAGIRALAEglkANCNLEVLDLNNNGLTdegaSALAETLASLK 221
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1775891392  716 SLRTLDLSGNNIEGR-----VPKSLSNCRYLEVLDLGKNSIDDI----FPCSLKSISTLRVLVLRSNKFhGKFGCQD 783
Cdd:cd00116    222 SLEVLNLGDNNLTDAgaaalASALLSPNISLLTLSLSCNDITDDgakdLAEVLAEKESLLELDLRGNKF-GEEGAQL 297
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
611-774 3.26e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 50.43  E-value: 3.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  611 PLSFFPSSAA--YLDFSNNSFSSAiipaigqylSSTVFFSLSRnriqgnipesicdSKSLQVLDLSNN---DLSGMFPQC 685
Cdd:cd00116     73 LLQGLTKGCGlqELDLSDNALGPD---------GCGVLESLLR-------------SSSLQELKLNNNglgDRGLRLLAK 130
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  686 -LTEKNDNLVVL----NLRENALNGSIPNAFPANCSLRTLDLSGNNIEGRVPKSL-----SNCRyLEVLDLGKNSIDD-- 753
Cdd:cd00116    131 gLKDLPPALEKLvlgrNRLEGASCEALAKALRANRDLKELNLANNGIGDAGIRALaeglkANCN-LEVLDLNNNGLTDeg 209
                          170       180
                   ....*....|....*....|...
gi 1775891392  754 --IFPCSLKSISTLRVLVLRSNK 774
Cdd:cd00116    210 asALAETLASLKSLEVLNLGDNN 232
PLN03150 PLN03150
hypothetical protein; Provisional
609-708 4.07e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 50.97  E-value: 4.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  609 EGPLSFFPSSAAYL------DFSNNSFSSAIIPAIGQyLSSTVFFSLSRNRIQGNIPESICDSKSLQVLDLSNNDLSGMF 682
Cdd:PLN03150   428 QGLRGFIPNDISKLrhlqsiNLSGNSIRGNIPPSLGS-ITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRV 506
                           90       100
                   ....*....|....*....|....*.
gi 1775891392  683 PQCLTEKNDNLVVLNLRENALNGSIP 708
Cdd:PLN03150   507 PAALGGRLLHRASFNFTDNAGLCGIP 532
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
304-586 4.37e-06

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 51.03  E-value: 4.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  304 SSRPLQTLVLQGTKFSGTLPEsIGYFENLTKLDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVPSFSQLKNLTVLN 383
Cdd:PLN03210   632 SLTGLRNIDLRGSKNLKEIPD-LSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDMSRCENLEILPTGINLKSLYRLN 710
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  384 LAH-NRLNGSL-LSTkweelpNLVNLDLRNNSITgNVPSSLfNLQTIRKIQLnYNLFSGSLNELSNVSSFLLDTLDLESN 461
Cdd:PLN03210   711 LSGcSRLKSFPdIST------NISWLDLDETAIE-EFPSNL-RLENLDELIL-CEMKSEKLWERVQPLTPLMTMLSPSLT 781
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  462 RLegpfpmSFLELQGLKILSLSFNNFTgrlnltvfkqlkNITRLELsSNSLSVETESTdSSSFPQMTTLKLASCN-LRMF 540
Cdd:PLN03210   782 RL------FLSDIPSLVELPSSIQNLH------------KLEHLEI-ENCINLETLPT-GINLESLESLDLSGCSrLRTF 841
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1775891392  541 PGFLKNQSKLNsldLSHNDLQgEIPLWIWGLENLNQLNLS-CNSLVG 586
Cdd:PLN03210   842 PDISTNISDLN---LSRTGIE-EVPWWIEKFSNLSFLDMNgCNNLQR 884
PLN03150 PLN03150
hypothetical protein; Provisional
263-350 6.62e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 50.20  E-value: 6.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  263 LHLGSSNLSGEFPQSIFQVSTLQTLDLSNNKLLQGSLPDFPSSRPLQTLVLQGTKFSGTLPESIGYFENLTKLDLASCNF 342
Cdd:PLN03150   423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502

                   ....*...
gi 1775891392  343 GGSIPNSI 350
Cdd:PLN03150   503 SGRVPAAL 510
PLN03150 PLN03150
hypothetical protein; Provisional
67-161 1.29e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.43  E-value: 1.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392   67 WNGVNC----TDG--CVTDLDLSEELILGGIDNSSSlfSLRFLRTLNLGFNRFNSLMPSGFNRLSNLSVLNMSNSGFNGQ 140
Cdd:PLN03150   404 WSGADCqfdsTKGkwFIDGLGLDNQGLRGFIPNDIS--KLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGS 481
                           90       100
                   ....*....|....*....|.
gi 1775891392  141 IPIEISNLTGLVSLDLTSSPL 161
Cdd:PLN03150   482 IPESLGQLTSLRILNLNGNSL 502
LRR_8 pfam13855
Leucine rich repeat;
667-727 5.66e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.13  E-value: 5.66e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  667 SLQVLDLSNNDLSGMFPQCLTeKNDNLVVLNLRENALNGSIPNAFPANCSLRTLDLSGNNI 727
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGAFK-GLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
331-389 7.38e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 7.38e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  331 NLTKLDLASCNFGGSIPNSILNLTQLTYLDLSSNKFVGPVP-SFSQLKNLTVLNLAHNRL 389
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPgAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
147-366 8.48e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 46.19  E-value: 8.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  147 NLTGLVSLDLTSSPLfqfptlkleNPNLRTFVQNL---SNLGELILNGVDLSAQG-REWCKALSSSLLNLTVLSLSGCAL 222
Cdd:cd00116     79 KGCGLQELDLSDNAL---------GPDGCGVLESLlrsSSLQELKLNNNGLGDRGlRLLAKGLKDLPPALEKLVLGRNRL 149
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  223 SGPLDSSLAK-LRYLSDIRL----DNNIFSSPVPDNYADFPTLTSL-----------HLGSSNLSGEFPQSIFqvstLQT 286
Cdd:cd00116    150 EGASCEALAKaLRANRDLKElnlaNNGIGDAGIRALAEGLKANCNLevldlnnngltDEGASALAETLASLKS----LEV 225
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  287 LDLSNNKLlqgslpdfpSSRPLQTLVlqgtkfSGTLPESIGyfenLTKLDLASCNFG----GSIPNSILNLTQLTYLDLS 362
Cdd:cd00116    226 LNLGDNNL---------TDAGAAALA------SALLSPNIS----LLTLSLSCNDITddgaKDLAEVLAEKESLLELDLR 286

                   ....
gi 1775891392  363 SNKF 366
Cdd:cd00116    287 GNKF 290
LRR_8 pfam13855
Leucine rich repeat;
716-775 1.23e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 1.23e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  716 SLRTLDLSGNNIEGRVPKSLSNCRYLEVLDLGKNSIDDIFPCSLKSISTLRVLVLRSNKF 775
Cdd:pfam13855    2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
716-773 1.31e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.39  E-value: 1.31e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  716 SLRTLDLSGNNIEGrvPKSLSNCRYLEVLDLGKNSIDDI--FPCSLKSISTLRVLVLRSN 773
Cdd:cd21340    121 SLRVLNISGNNIDS--LEPLAPLRNLEQLDASNNQISDLeeLLDLLSSWPSLRELDLTGN 178
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
230-436 1.43e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 45.42  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  230 LAKLRYLSDIRLDNNIFS----SPVPDNYADFPTLTSLHLGSSNLSGE------FPQSIFQVSTLQTLDLSNNKL---LQ 296
Cdd:cd00116     19 LPKLLCLQVLRLEGNTLGeeaaKALASALRPQPSLKELCLSLNETGRIprglqsLLQGLTKGCGLQELDLSDNALgpdGC 98
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  297 GSLPDFPSSRPLQTLVL-------QGTKFSGT-LPESIgyfENLTKLDLASCNFGGSIPNSILNL----TQLTYLDLSSN 364
Cdd:cd00116     99 GVLESLLRSSSLQELKLnnnglgdRGLRLLAKgLKDLP---PALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANN 175
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  365 KFVGP--------VPSFSQLKNLTVLNLAHNRLNGSLLSTKWEELPNLVNLDLRNNSITGN-----VPSSLFNLQTIRKI 431
Cdd:cd00116    176 GIGDAgiralaegLKANCNLEVLDLNNNGLTDEGASALAETLASLKSLEVLNLGDNNLTDAgaaalASALLSPNISLLTL 255

                   ....*
gi 1775891392  432 QLNYN 436
Cdd:cd00116    256 SLSCN 260
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
659-749 1.49e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.39  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  659 PESICD-SKSLQVLDLSNNDLSGMFP-QCLTekndNLVVLNLRENALN--GSIPNAFPANCSLRTLDLSGNNIeGRVPK- 733
Cdd:cd21340    112 PRSLAAlSNSLRVLNISGNNIDSLEPlAPLR----NLEQLDASNNQISdlEELLDLLSSWPSLRELDLTGNPV-CKKPKy 186
                           90
                   ....*....|....*....
gi 1775891392  734 ---SLSNCRYLEVLDlGKN 749
Cdd:cd21340    187 rdkIILASKSLEVLD-GKE 204
LRR_8 pfam13855
Leucine rich repeat;
453-512 1.72e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.72e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  453 LDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTgRLNLTVFKQLKNITRLELSSNSL 512
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT-TLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
888-946 2.47e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.20  E-value: 2.47e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1775891392  888 LYLLNFSHNYLSGEIPSSIGNLSQLGSLDLSRNRLTGQIPQQLAGLSFLSVLNLSYNLL 946
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
354-414 2.87e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.87e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1775891392  354 TQLTYLDLSSNKFVG-PVPSFSQLKNLTVLNLAHNRLNGslLSTKW-EELPNLVNLDLRNNSI 414
Cdd:pfam13855    1 PNLRSLDLSNNRLTSlDDGAFKGLSNLKVLDLSNNLLTT--LSPGAfSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
453-513 4.16e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.42  E-value: 4.16e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  453 LDTLDLESNRLEGPFPMSFLELQGLKILSLSFNNFTGRLNLTVfKQLKNITRLELSSNSLS 513
Cdd:PLN03150   444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESL-GQLTSLRILNLNGNSLS 503
LRR_8 pfam13855
Leucine rich repeat;
103-161 4.33e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 4.33e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1775891392  103 LRTLNLGFNRFNSLMPSGFNRLSNLSVLNMSNSGFNGQIPIEISNLTGLVSLDLTSSPL 161
Cdd:pfam13855    3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
525-584 1.12e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 1.12e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  525 PQMTTLKLASCNL-RMFPGFLKNQSKLNSLDLSHNDLQGEIPLWIWGLENLNQLNLSCNSL 584
Cdd:pfam13855    1 PNLRSLDLSNNRLtSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
80-142 1.57e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.50  E-value: 1.57e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1775891392   80 LDLSEELILGGIdnSSSLFSLRFLRTLNLGFNRFNSLMPSGFNRLSNLSVLNMSNSGFNGQIP 142
Cdd:PLN03150   447 INLSGNSIRGNI--PPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
622-753 1.82e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 42.08  E-value: 1.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  622 LDFSNNSFSSAIIPAIGQYLSS--TVF-FSLSRNRI--QG--NIPESICDSKSLQVLDLSNNDLSG----MFPQCLTEkN 690
Cdd:COG5238    185 VYLGCNQIGDEGIEELAEALTQntTVTtLWLKRNPIgdEGaeILAEALKGNKSLTTLDLSNNQIGDegviALAEALKN-N 263
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1775891392  691 DNLVVLNLRENAL--NG--SIPNAFPANCSLRTLDLSGNNIEGR----VPKSLSNCRYLEVLDLGKNSIDD 753
Cdd:COG5238    264 TTVETLYLSGNQIgaEGaiALAKALQGNTTLTSLDLSVNRIGDEgaiaLAEGLQGNKTLHTLNLAYNGIGA 334
PLN03150 PLN03150
hypothetical protein; Provisional
520-586 2.35e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.11  E-value: 2.35e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1775891392  520 DSSSFPQMTTLKLASCNLR-MFPGFLKNQSKLNSLDLSHNDLQGEIPLWIWGLENLNQLNLSCNSLVG 586
Cdd:PLN03150   437 DISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSG 504
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
666-799 4.75e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.77  E-value: 4.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  666 KSLQVLDLSNNDLSGM--FPQCLtekndNLVVLNLRENALNgSIPNaFPANCSLRTLDLSGNNI---EGrvpksLSNCRY 740
Cdd:cd21340      2 KRITHLYLNDKNITKIdnLSLCK-----NLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNNQIekiEN-----LENLVN 69
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1775891392  741 LEVLDLGKNSIDDIfpCSLKSISTLRVLVL------RSNKFHgkFGCQDTNGTWKSLQIVDISRN 799
Cdd:cd21340     70 LKKLYLGGNRISVV--EGLENLTNLEELHIenqrlpPGEKLT--FDPRSLAALSNSLRVLNISGN 130
PLN03150 PLN03150
hypothetical protein; Provisional
182-278 5.06e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 40.95  E-value: 5.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1775891392  182 SNLGELILNGVDLSAQG-REWCKALSSSLLNLTVLSLSGCALSGPLDSSLAKLRYLSDIRLDNNIFSSPVPDNYADFPTL 260
Cdd:PLN03150   413 STKGKWFIDGLGLDNQGlRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSL 492
                           90
                   ....*....|....*...
gi 1775891392  261 TSLHLGSSNLSGEFPQSI 278
Cdd:PLN03150   493 RILNLNGNSLSGRVPAAL 510
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
347-415 8.72e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 39.00  E-value: 8.72e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1775891392  347 PNSILNLTQ-LTYLDLSSNKFVGPVPsFSQLKNLTVLNLAHNRLNG-----SLLSTkweeLPNLVNLDLRNNSIT 415
Cdd:cd21340    112 PRSLAALSNsLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISDleellDLLSS----WPSLRELDLTGNPVC 181
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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