NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|521760479|gb|JAA97765|]
View 

Annexin A7-like protein [Crotalus horridus]

Protein Classification

annexin( domain architecture ID 10446041)

annexin belongs to a family of calcium- and phospholipid-binding proteins that have been implicated in many cellular processes, including channel formation, membrane fusion, vesicle transport, and regulation of phospholipase A2 activity

CATH:  1.10.220.10
Gene Ontology:  GO:0005509|GO:0005544|GO:0048306|GO:0003723
PubMed:  15059252|1646719
SCOP:  4001063
TCDB:  1.A.31

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 158-223 2.74e-31

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 114.49  E-value: 2.74e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  158 RDAEILRKAMKGFGTDEQAIIDVVSNRSNEQRQQIKSAFKTMYGKDLIKDLKSELSGNMEELILAL 223
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 230-295 7.98e-28

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 105.25  E-value: 7.98e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  230 YDAWSLRHAMKGAGTQENVLIEILCTRTNREIQEIVQCYKSEFGRDIEHDVRADTSGHFERLLVSM 295
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 389-454 8.12e-25

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 96.77  E-value: 8.12e-25
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  389 FFAERLYHAMKGAGTDDSTLVRIIVTRSEIDLVQIKQLFTQMYHKTLATMISSDTGGDYRSLLLAI 454
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 313-379 9.00e-19

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


:

Pssm-ID: 395139  Cd Length: 66  Bit Score: 79.82  E-value: 9.00e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 521760479  313 QDAQRLYQAgEGKLGTDESCFNMILASRSFPQLKATVEAYSQIANRDLLSTIGREFSGNVERGLKTI 379
Cdd:pfam00191   1 YDAELLRKA-MKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
PHA03378 super family cl33729
EBNA-3B; Provisional
 23-169 2.75e-08

EBNA-3B; Provisional


The actual alignment was detected with superfamily member PHA03378:

Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 56.23  E-value: 2.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  23 EYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEfPGFAGYPTAPGGYPPASSGYPG-LPQPGGMPTY---PGGAGFGVPP 98
Cdd:PHA03378 688 QWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAA-TGRARPPAAAPGRARPPAAAPGrARPPAAAPGRarpPAAAPGRARP 766

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 521760479  99 SGSGFGCPQPQPQTYSGGGPVQMPAGYPggrTPSTPlqPAALTQSMQgTIQPAPNFDAGRDAEILRKAMKG 169
Cdd:PHA03378 767 PAAAPGAPTPQPPPQAPPAPQQRPRGAP---TPQPP--PQAGPTSMQ-LMPRAAPGQQGPTKQILRQLLTG 831
 
Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 158-223 2.74e-31

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 114.49  E-value: 2.74e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  158 RDAEILRKAMKGFGTDEQAIIDVVSNRSNEQRQQIKSAFKTMYGKDLIKDLKSELSGNMEELILAL 223
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 230-295 7.98e-28

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 105.25  E-value: 7.98e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  230 YDAWSLRHAMKGAGTQENVLIEILCTRTNREIQEIVQCYKSEFGRDIEHDVRADTSGHFERLLVSM 295
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 389-454 8.12e-25

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 96.77  E-value: 8.12e-25
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  389 FFAERLYHAMKGAGTDDSTLVRIIVTRSEIDLVQIKQLFTQMYHKTLATMISSDTGGDYRSLLLAI 454
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
171-223 6.26e-24

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 94.01  E-value: 6.26e-24
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 521760479   171 GTDEQAIIDVVSNRSNEQRQQIKSAFKTMYGKDLIKDLKSELSGNMEELILAL 223
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
ANX smart00335
Annexin repeats;
243-295 7.67e-21

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 85.54  E-value: 7.67e-21
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 521760479   243 GTQENVLIEILCTRTNREIQEIVQCYKSEFGRDIEHDVRADTSGHFERLLVSM 295
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 313-379 9.00e-19

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 79.82  E-value: 9.00e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 521760479  313 QDAQRLYQAgEGKLGTDESCFNMILASRSFPQLKATVEAYSQIANRDLLSTIGREFSGNVERGLKTI 379
Cdd:pfam00191   1 YDAELLRKA-MKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
402-454 9.20e-19

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 79.37  E-value: 9.20e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 521760479   402 GTDDSTLVRIIVTRSEIDLVQIKQLFTQMYHKTLATMISSDTGGDYRSLLLAI 454
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
ANX smart00335
Annexin repeats;
327-376 6.11e-12

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 60.11  E-value: 6.11e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 521760479   327 GTDESCFNMILASRSFPQLKATVEAYSQIANRDLLSTIGREFSGNVERGL 376
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLL 50
PHA03378 PHA03378
EBNA-3B; Provisional
 23-169 2.75e-08

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 56.23  E-value: 2.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  23 EYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEfPGFAGYPTAPGGYPPASSGYPG-LPQPGGMPTY---PGGAGFGVPP 98
Cdd:PHA03378 688 QWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAA-TGRARPPAAAPGRARPPAAAPGrARPPAAAPGRarpPAAAPGRARP 766

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 521760479  99 SGSGFGCPQPQPQTYSGGGPVQMPAGYPggrTPSTPlqPAALTQSMQgTIQPAPNFDAGRDAEILRKAMKG 169
Cdd:PHA03378 767 PAAAPGAPTPQPPPQAPPAPQQRPRGAP---TPQPP--PQAGPTSMQ-LMPRAAPGQQGPTKQILRQLLTG 831
MISS pfam15822
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ...
 2-153 1.12e-04

MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.


Pssm-ID: 318115 [Multi-domain]  Cd Length: 238  Bit Score: 43.44  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    2 SYPGYPPSGYPSfpgypptgqEYPPANQYSYPAVPGGFPP-VGGSEYNVAP-PTGEFPGFAGYPTAPGGYPPASSGYPGL 79
Cdd:pfam15822  21 PKPGQPPQGWPG---------SNPWNNPSAPPAVPSGLPPsTAPSTVPFGPaPTGMYPSIPLTGPSPGPPAPFPPSGPSC 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 521760479   80 PQPGG---MPTYPGGAGFGVPPSGSgfgCPQPQ-PQTYsgGGPVQMPAGYPGGRTPSTPLQPAALTQSMQgtiQPAPN 153
Cdd:pfam15822  92 PPPGGpypAPTVPGPGPIGPYPTPN---MPFPElPRPY--GAPTDPAAAAPSGPWGSMSSGPWAPGMGGQ---YPAPN 161
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 7-160 7.49e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 38.89  E-value: 7.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   7 PPSGYPSFP--GYPPTGQEYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEFPGFAGYPTAP----GGYPPASSGYP-GL 79
Cdd:COG5180  311 PPATRPVRPpgGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPrpgsSGGDGAPFQPPnGA 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  80 PQPGGM----PTYPGGAGFGVPPSGSGfGCPQPQPQTYSGGGPVQMPAGYPGGRTPSTPLQPA-ALTQSMQGTIQPAPNF 154
Cdd:COG5180  391 PQPGLGrrgaPGPPMGAGDLVQAALDG-GGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAgLADQAGAAASTAMADF 469


                 ....*.
gi 521760479 155 DAGRDA 160
Cdd:COG5180  470 VAPVTD 475
 
Name Accession Description Interval E-value
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 158-223 2.74e-31

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 114.49  E-value: 2.74e-31
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  158 RDAEILRKAMKGFGTDEQAIIDVVSNRSNEQRQQIKSAFKTMYGKDLIKDLKSELSGNMEELILAL 223
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 230-295 7.98e-28

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 105.25  E-value: 7.98e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  230 YDAWSLRHAMKGAGTQENVLIEILCTRTNREIQEIVQCYKSEFGRDIEHDVRADTSGHFERLLVSM 295
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 389-454 8.12e-25

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 96.77  E-value: 8.12e-25
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479  389 FFAERLYHAMKGAGTDDSTLVRIIVTRSEIDLVQIKQLFTQMYHKTLATMISSDTGGDYRSLLLAI 454
Cdd:pfam00191   1 YDAELLRKAMKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
171-223 6.26e-24

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 94.01  E-value: 6.26e-24
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 521760479   171 GTDEQAIIDVVSNRSNEQRQQIKSAFKTMYGKDLIKDLKSELSGNMEELILAL 223
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
ANX smart00335
Annexin repeats;
243-295 7.67e-21

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 85.54  E-value: 7.67e-21
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 521760479   243 GTQENVLIEILCTRTNREIQEIVQCYKSEFGRDIEHDVRADTSGHFERLLVSM 295
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
Annexin pfam00191
Annexin; This family of annexins also includes giardin that has been shown to function as an ...
 313-379 9.00e-19

Annexin; This family of annexins also includes giardin that has been shown to function as an annexin.


Pssm-ID: 395139  Cd Length: 66  Bit Score: 79.82  E-value: 9.00e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 521760479  313 QDAQRLYQAgEGKLGTDESCFNMILASRSFPQLKATVEAYSQIANRDLLSTIGREFSGNVERGLKTI 379
Cdd:pfam00191   1 YDAELLRKA-MKGLGTDESTLIEILATRSNAQLQAIREAYKKLYGKDLEKDIKSETSGDFEKLLLAL 66
ANX smart00335
Annexin repeats;
402-454 9.20e-19

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 79.37  E-value: 9.20e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 521760479   402 GTDDSTLVRIIVTRSEIDLVQIKQLFTQMYHKTLATMISSDTGGDYRSLLLAI 454
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLLLAL 53
ANX smart00335
Annexin repeats;
327-376 6.11e-12

Annexin repeats;


Pssm-ID: 197661  Cd Length: 53  Bit Score: 60.11  E-value: 6.11e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 521760479   327 GTDESCFNMILASRSFPQLKATVEAYSQIANRDLLSTIGREFSGNVERGL 376
Cdd:smart00335   1 GTDEKTLIEILASRSNAQLQAIKQAYKKRYGKDLEDDIKSETSGDFEKLL 50
PHA03378 PHA03378
EBNA-3B; Provisional
 23-169 2.75e-08

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 56.23  E-value: 2.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  23 EYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEfPGFAGYPTAPGGYPPASSGYPG-LPQPGGMPTY---PGGAGFGVPP 98
Cdd:PHA03378 688 QWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAA-TGRARPPAAAPGRARPPAAAPGrARPPAAAPGRarpPAAAPGRARP 766

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 521760479  99 SGSGFGCPQPQPQTYSGGGPVQMPAGYPggrTPSTPlqPAALTQSMQgTIQPAPNFDAGRDAEILRKAMKG 169
Cdd:PHA03378 767 PAAAPGAPTPQPPPQAPPAPQQRPRGAP---TPQPP--PQAGPTSMQ-LMPRAAPGQQGPTKQILRQLLTG 831
PHA03378 PHA03378
EBNA-3B; Provisional
 4-141 2.33e-05

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 46.98  E-value: 2.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   4 PGYPPSGYPSfPGYPP---TGQEYPPAnqysypAVPGGFPPVGGSEYNVAPPTGEfPGFAGYPTAPGGYPPASSGYPGLP 80
Cdd:PHA03378 703 PMRPPAAPPG-RAQRPaaaTGRARPPA------AAPGRARPPAAAPGRARPPAAA-PGRARPPAAAPGRARPPAAAPGAP 774

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 521760479  81 QPGGMPTYPGGagfgvpPSGSGFGCPQPQPQTYSGGGPVQ-MPAGYPGGRTPSTPLQPAALT 141
Cdd:PHA03378 775 TPQPPPQAPPA------PQQRPRGAPTPQPPPQAGPTSMQlMPRAAPGQQGPTKQILRQLLT 830
MISS pfam15822
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ...
 2-153 1.12e-04

MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.


Pssm-ID: 318115 [Multi-domain]  Cd Length: 238  Bit Score: 43.44  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    2 SYPGYPPSGYPSfpgypptgqEYPPANQYSYPAVPGGFPP-VGGSEYNVAP-PTGEFPGFAGYPTAPGGYPPASSGYPGL 79
Cdd:pfam15822  21 PKPGQPPQGWPG---------SNPWNNPSAPPAVPSGLPPsTAPSTVPFGPaPTGMYPSIPLTGPSPGPPAPFPPSGPSC 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 521760479   80 PQPGG---MPTYPGGAGFGVPPSGSgfgCPQPQ-PQTYsgGGPVQMPAGYPGGRTPSTPLQPAALTQSMQgtiQPAPN 153
Cdd:pfam15822  92 PPPGGpypAPTVPGPGPIGPYPTPN---MPFPElPRPY--GAPTDPAAAAPSGPWGSMSSGPWAPGMGGQ---YPAPN 161
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 5-150 4.84e-04

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 42.69  E-value: 4.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    5 GYPPSGYPSFPGYPPTGQEYPPANQYsyPAVPGGFPPVGGSEynvAPPTGEFPGFAGYPTAPGGYPPASSGYPGLPQPGG 84
Cdd:pfam09606 154 QAGGMMQPSSGQPGSGTPNQMGPNGG--PGQGQAGGMNGGQQ---GPMGGQMPPQMGVPGMPGPADAGAQMGQQAQANGG 228

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479   85 MPTYPGGAGFGVPPSGSGFGCPQP----------QPQTYSGGGPVQMPAGYPGGRTPSTPLQPAALTQSMQGTIQP 150
Cdd:pfam09606 229 MNPQQMGGAPNQVAMQQQQPQQQGqqsqlgmginQMQQMPQGVGGGAGQGGPGQPMGPPGQQPGAMPNVMSIGDQN 304
PHA03247 PHA03247
large tegument protein UL36; Provisional
 4-152 6.36e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 6.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    4 PGYPPSGYPSfPGYPPtgqeyPPANQYSYPAVPGGFPP---------VGGSEYNVAPPTGEFPGfagYPTAPGgYPPASS 74
Cdd:PHA03247 2816 AALPPAASPA-GPLPP-----PTSAQPTAPPPPPGPPPpslplggsvAPGGDVRRRPPSRSPAA---KPAAPA-RPPVRR 2885

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 521760479   75 gypgLPQPggmPTYPGGAGFGVPPSG-SGFGCPQPQPQTYSGGGPVQMPAGYPGGRTPSTPLQPAALTQSMQGTIQPAP 152
Cdd:PHA03247 2886 ----LARP---AVSRSTESFALPPDQpERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 3-143 6.49e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 42.45  E-value: 6.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    3 YPGYPPSGYPSFPGYPPTgqeyPPANQYSYPAVP-----GGFPPVGGSeYNVAPPTGEFPGfagyPTAPGGYPPASSGYP 77
Cdd:pfam03154 238 HPQRLPSPHPPLQPMTQP----PPPSQVSPQPLPqpslhGQMPPMPHS-LQTGPSHMQHPV----PPQPFPLTPQSSQSQ 308

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479   78 GLPQPGGMPTYPGGAGFGVPPSGSGFGCPQPQPQTYSGGGPVQMPAGYPggrTPSTPLQPAALTQS 143
Cdd:pfam03154 309 VPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKP---PPTTPIPQLPNPQS 371
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 4-152 9.45e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.99  E-value: 9.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    4 PGyPPSGYPSFPgypPTGQEYPPANQYSYPAVPGGFPpvggSEYNVAPPTGEFPGFAGYPTAPGGYPPASSGYPGLPQPG 83
Cdd:PRK10263  364 PG-PQTGEPVIA---PAPEGYPQQSQYAQPAVQYNEP----LQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYA 435

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 521760479   84 GMPTYPGGAGFGVPPSGSGFGCPQPQPQTYSgggPVQMPAGYPGGRTPSTPLQPaaltqsmQGTIQPAP 152
Cdd:PRK10263  436 PAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQ---TYQQPAAQEPLYQQPQPVEQ-------QPVVEPEP 494
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 34-161 9.57e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 9.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  34 AVPGGFPPVGGSEYNVAPPTGEFPGFAGYPTAPGGYPPASSGYPGLPQPGGMPTYPGGAGFGVPPSGSGFGCPQPQPQTY 113
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 521760479 114 SGGGPVqmpagYPGGRTPSTPLQPAALTQSMQGTIQPAPNFDAGRDAE 161
Cdd:PRK07764 666 GDGWPA-----KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT 708
PHA03247 PHA03247
large tegument protein UL36; Provisional
 4-154 1.69e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    4 PGYPPSGYPSFPGYPPTGQEYPPANQysyPAVPGGFPPVGgseynvAPPTGEFPGFAGYPTAP-GGYPPASSGYPGLPQP 82
Cdd:PHA03247 2722 PPGPAAARQASPALPAAPAPPAVPAG---PATPGGPARPA------RPPTTAGPPAPAPPAAPaAGPPRRLTRPAVASLS 2792

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 521760479   83 GGMPTYPGGAGFGVPPSG-SGFGCPQPQPQTYSGGGPvqmPAGYPGGRTPSTPLQPAALTQSMQGTIQPAPNF 154
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAvLAPAAALPPAASPAGPLP---PPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDV 2862
FAP pfam07174
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ...
 12-97 1.80e-03

Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.


Pssm-ID: 429334  Cd Length: 301  Bit Score: 40.29  E-value: 1.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   12 PSFPGYPPTGQEYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEFPGFAGYPTAPGGYPPASSGYPGLPQPGGMPTYPGG 91
Cdd:pfam07174  43 PAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNAPNAPPPPADPNAPPPPPADPNAPPPPAVDPNAPEPGRIDNAVGG 122


                  ....*.
gi 521760479   92 AGFGVP 97
Cdd:pfam07174 123 FSYVVP 128
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
 8-124 2.00e-03

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 40.58  E-value: 2.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   8 PSGYPS-FPGYPPTGQEYPPANqysyPAVPGGFPPVGGSEynVAPPTGEFPGfagyptaPGGYPPASSGYPGLPQPGGMP 86
Cdd:PRK13729 130 ATGEPVpQMPASPPGPEGEPQP----GNTPVSFPPQGSVA--VPPPTAFYPG-------NGVTPPPQVTYQSVPVPNRIQ 196

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 521760479  87 TY-----PGGAGFGVP--PSGSgF----------------GCPQPQPQTYSGGGPVQMPAG 124
Cdd:PRK13729 197 RKtftynEGKKGPSLPyiPSGS-FakamliegadanasvtGNESTVPMQLRITGLVEMPNS 256
Pro-rich pfam15240
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
 4-134 2.07e-03

Proline-rich protein; This family includes several eukaryotic proline-rich proteins.


Pssm-ID: 464580 [Multi-domain]  Cd Length: 167  Bit Score: 38.87  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    4 PGYPPSGYPSFPGYPPTGQEYPPanqysyPAVPGGFPPVGGSEYNVAPPTGEFPGfaGYPTAPGGYPPASSGYPGLPQPG 83
Cdd:pfam15240  47 QGPPPGGFPPQPPASDDPPGPPP------PGGPQQPPPQGGKQKPQGPPPQGGPR--PPPGKPQGPPPQGGNQQQGPPPP 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 521760479   84 GMPTYPGGAGFGVPPSGSGFGCPQPQPQTYSGGGPVQMPagyPGGRTPSTP 134
Cdd:pfam15240 119 GKPQGPPPQGGGPPPQGGNQQGPPPPPPGNPQGPPQRPP---QPGNPQGPP 166
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 16-157 2.34e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 2.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  16 GYPPTGQEYPPAnqysyPAVPGGFPPVGGSeynvAPPTGEFPGFAGYPTAPGGYPPASSGYPGLPQPGGMPTYPGGAGFG 95
Cdd:PRK07764 384 RLGVAGGAGAPA-----AAAPSAAAAAPAA----APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP 454

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 521760479  96 VPPSGsgfgcPQPQPQTYSGGGPVQMPAGYPGGRTPSTPLQPAALTQSMQGTIQPAPNFDAG 157
Cdd:PRK07764 455 SPPPA-----AAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
Pro-rich pfam15240
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
 8-120 3.09e-03

Proline-rich protein; This family includes several eukaryotic proline-rich proteins.


Pssm-ID: 464580 [Multi-domain]  Cd Length: 167  Bit Score: 38.48  E-value: 3.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    8 PSGYPSFPGYPPTGQEYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEFPGfagyPTAPGGYPPASSGYPGLPQPggmpt 87
Cdd:pfam15240  73 PQQPPPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQG----PPPQGGGPPPQGGNQQGPPP----- 143

                          90       100       110
                  ....*....|....*....|....*....|...
gi 521760479   88 ypggagfgvPPSGSGFGCPQPQPQTYSGGGPVQ 120
Cdd:pfam15240 144 ---------PPPGNPQGPPQRPPQPGNPQGPPQ 167
PHA03247 PHA03247
large tegument protein UL36; Provisional
 4-139 3.55e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 3.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    4 PGYPP-SGYPSFPGYPPTGQEYPPANQYSYPAVPGGFPP----------VGGSEYNVAPPTgEFPGFAGYP--------- 63
Cdd:PHA03247 2589 PDAPPqSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPppspspaanePDPHPPPTVPPP-ERPRDDPAPgrvsrprra 2667

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521760479   64 TAPGGYPPASSGYPGLPQPGGMPTYPGGAGFGVPPSGSgfGCPQPQPQTYSGGGPVQMPAGYPGGRTPSTPLQPAA 139
Cdd:PHA03247 2668 RRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPP--PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAP 2741
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 16-166 4.21e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 39.66  E-value: 4.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  16 GYPPTGQEYPPANQYSYPAVPggfPPVGGSEYNVAPPTGEFPGFAgyptAPGGYPPASSGYPGLPQPGGMPTYP--GGAG 93
Cdd:PRK14959 378 ASAPSGSAAEGPASGGAATIP---TPGTQGPQGTAPAAGMTPSSA----APATPAPSAAPSPRVPWDDAPPAPPrsGIPP 450

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 521760479  94 FGVPPSGSGFGCPQPQPQTYSGGG--PVQMPAGYPGGRTPSTPLQPAALTQSMQGTiqpapNFDAGRDAEILRKA 166
Cdd:PRK14959 451 RPAPRMPEASPVPGAPDSVASASDapPTLGDPSDTAEHTPSGPRTWDGFLEFCQGR-----NGQGGRLATVLRQA 520
PHA03247 PHA03247
large tegument protein UL36; Provisional
 14-139 4.79e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 4.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   14 FPGYPptGQEYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEFPGFAGYPTAPGG--YPP------------AS--SGYP 77
Cdd:PHA03247 2474 FPGAP--VYRRPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGepVHPrmltwirgleelASddAGDP 2551

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 521760479   78 GLPQPGGMPtyPGGAGFGVPPS-----------GSGFGCPQPQPQTYSGGGPVQmPAGYPGGRTPSTPLQPAA 139
Cdd:PHA03247 2552 PPPLPPAAP--PAAPDRSVPPPrpaprpsepavTSRARRPDAPPQSARPRAPVD-DRGDPRGPAPPSPLPPDT 2621
DUF3824 pfam12868
Domain of unknwon function (DUF3824); This is a repeating domain found in fungal proteins. It ...
 5-82 5.36e-03

Domain of unknwon function (DUF3824); This is a repeating domain found in fungal proteins. It is proline-rich, and the function is not known.


Pssm-ID: 372351 [Multi-domain]  Cd Length: 145  Bit Score: 37.41  E-value: 5.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479    5 GYPPSGYPSFPGYPPT--GQEYPPANQY-----SYPAVPGGFPP-VGGSEYNVA---PPTGEFPgfagyPTAPGGYPPAS 73
Cdd:pfam12868  55 PYSPSPYPPSPAGPYAsqGQYYPETNYFppppgSTPQPPVDPQPnAPPPPYNPAdypPPPGAAP-----PPQPYQYPPPP 129


                  ....*....
gi 521760479   74 SGYPGLPQP 82
Cdd:pfam12868 130 GPDPYAPRP 138
dnaA PRK14086
chromosomal replication initiator protein DnaA;
4-137 6.94e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 39.04  E-value: 6.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   4 PGYP-------PSGYPSFP----------GYPPtGQEYPPANQYSYPAVPGgfppvggseynvAPPTGEFPGFAGYPTAP 66
Cdd:PRK14086 144 PAYPayqqrpePGAWPRAAddygwqqqrlGFPP-RAPYASPASYAPEQERD------------REPYDAGRPEYDQRRRD 210

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 521760479  67 GGYPPASSGYPG-------LPQPGGmptypGGAGFGVPPSGSGFGCPQPQPQTYSGGGPVQMPAGYPGGRTPSTPLQP 137
Cdd:PRK14086 211 YDHPRPDWDRPRrdrtdrpEPPPGA-----GHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGEPTARLNP 283
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 7-160 7.49e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 38.89  E-value: 7.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   7 PPSGYPSFP--GYPPTGQEYPPANQYSYPAVPGGFPPVGGSEYNVAPPTGEFPGFAGYPTAP----GGYPPASSGYP-GL 79
Cdd:COG5180  311 PPATRPVRPpgGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPrpgsSGGDGAPFQPPnGA 390

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479  80 PQPGGM----PTYPGGAGFGVPPSGSGfGCPQPQPQTYSGGGPVQMPAGYPGGRTPSTPLQPA-ALTQSMQGTIQPAPNF 154
Cdd:COG5180  391 PQPGLGrrgaPGPPMGAGDLVQAALDG-GGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAgLADQAGAAASTAMADF 469


                 ....*.
gi 521760479 155 DAGRDA 160
Cdd:COG5180  470 VAPVTD 475
dnaA PRK14086
chromosomal replication initiator protein DnaA;
7-150 8.92e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 38.65  E-value: 8.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   7 PPSGYPSFPGYPPTGQEYPPANQYSYPAVPGGFPPvgGSEYnvAPPTGEFPGFAGYPTAPG-GYPPASSGYPGLPQPGGM 85
Cdd:PRK14086 142 ARPAYPAYQQRPEPGAWPRAADDYGWQQQRLGFPP--RAPY--ASPASYAPEQERDREPYDaGRPEYDQRRRDYDHPRPD 217

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 521760479  86 PTYPGGAGFGVPPSGSGFGCPQpqpqtYSGGGPVQMPAGYPGGRTPSTPLQPAALTQSMQGTIQP 150
Cdd:PRK14086 218 WDRPRRDRTDRPEPPPGAGHVH-----RGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGEP 277
DUF1373 pfam07117
Protein of unknown function (DUF1373); This family consists of several hypothetical proteins ...
 56-152 9.48e-03

Protein of unknown function (DUF1373); This family consists of several hypothetical proteins which seem to be specific to Oryzias latipes (Japanese ricefish). Members of this family are typically around 200 residues in length. The function of this family is unknown.


Pssm-ID: 462093 [Multi-domain]  Cd Length: 212  Bit Score: 37.46  E-value: 9.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521760479   56 FPGFAGYPTAPGGYPPASSGYPGLPQPGGMPTYPGGAGFGVPPSGSGFGCPQPQPQTYSGGGPVQMPAGYPGGRTPSTPL 135
Cdd:pfam07117  35 PPGQEPEPPRPEEEEGQGGGGGTFPFPGSPEPEPGGGGSGPMPMSASAPEPEPAKAKPQRPAPAQGHGHGGGGDSDSSGS 114

                          90
                  ....*....|....*..
gi 521760479  136 QPAALTQSMQGTIQPAP 152
Cdd:pfam07117 115 GSGHQGSGGAGAGAGAP 131
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH