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Conserved domains on  [gi|2276111379|dbj|GKM07501|]
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anti-adapter protein IraP [Klebsiella variicola]

Protein Classification

anti-adapter protein IraP( domain architecture ID 10013469)

anti-adapter protein IraP inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10244 PRK10244
anti-adapter protein IraP;
1-86 3.19e-27

anti-adapter protein IraP;


:

Pssm-ID: 236666  Cd Length: 88  Bit Score: 94.59  E-value: 3.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2276111379  1 MKNLIAELLVKLAQKEEEAKELTVQVEALEIVVTALLRHMEHDAQQALIQDIEQAIDQV-TPCPPVNDQDAMLLQQYLKK 79
Cdd:PRK10244   1 MKNLIAELLAKLAQKEEESKELTAQVEALELLVTAMLRTMGKNGQQELIEQVEGAINAVsKPDDSVPDSDTELLLTYVNK 80


                 ....*..
gi 2276111379 80 LLRHPRS 86
Cdd:PRK10244  81 LLRHPRQ 87
 
Name Accession Description Interval E-value
PRK10244 PRK10244
anti-adapter protein IraP;
1-86 3.19e-27

anti-adapter protein IraP;


Pssm-ID: 236666  Cd Length: 88  Bit Score: 94.59  E-value: 3.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2276111379  1 MKNLIAELLVKLAQKEEEAKELTVQVEALEIVVTALLRHMEHDAQQALIQDIEQAIDQV-TPCPPVNDQDAMLLQQYLKK 79
Cdd:PRK10244   1 MKNLIAELLAKLAQKEEESKELTAQVEALELLVTAMLRTMGKNGQQELIEQVEGAINAVsKPDDSVPDSDTELLLTYVNK 80


                 ....*..
gi 2276111379 80 LLRHPRS 86
Cdd:PRK10244  81 LLRHPRQ 87
Anti-adapt_IraP pfam10796
Sigma-S stabilization anti-adaptor protein; This family is conserved in Enterobacteriaceae. It ...
 1-85 2.28e-24

Sigma-S stabilization anti-adaptor protein; This family is conserved in Enterobacteriaceae. It is one of a series of proteins, expressed by these bacteria in response to stress, that help to regulate Sigma-S, the stationary phase sigma factor of Escherichia coli and Salmonella. IraP is essential for Sigma-S stabilization in some but not all starvation conditions.


Pssm-ID: 431501  Cd Length: 86  Bit Score: 87.40  E-value: 2.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2276111379  1 MKNLIAELLVKLAQKEEEAKELTVQVEALEIVVTALLRHMEHDAQQALIQDIEQAIDQVTPC-PPVNDQDAMLLQQYLKK 79
Cdd:pfam10796  1 MKNLISELLIKLAQKEAESKELTAQVEALEILVSALVLTVSKGGQQELIDSIEKAINSVPESsDEILKSDAELLLQNFQR 80


                 ....*.
gi 2276111379 80 LLRHPR 85
Cdd:pfam10796 81 LLTVSR 86
 
Name Accession Description Interval E-value
PRK10244 PRK10244
anti-adapter protein IraP;
1-86 3.19e-27

anti-adapter protein IraP;


Pssm-ID: 236666  Cd Length: 88  Bit Score: 94.59  E-value: 3.19e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2276111379  1 MKNLIAELLVKLAQKEEEAKELTVQVEALEIVVTALLRHMEHDAQQALIQDIEQAIDQV-TPCPPVNDQDAMLLQQYLKK 79
Cdd:PRK10244   1 MKNLIAELLAKLAQKEEESKELTAQVEALELLVTAMLRTMGKNGQQELIEQVEGAINAVsKPDDSVPDSDTELLLTYVNK 80


                 ....*..
gi 2276111379 80 LLRHPRS 86
Cdd:PRK10244  81 LLRHPRQ 87
Anti-adapt_IraP pfam10796
Sigma-S stabilization anti-adaptor protein; This family is conserved in Enterobacteriaceae. It ...
 1-85 2.28e-24

Sigma-S stabilization anti-adaptor protein; This family is conserved in Enterobacteriaceae. It is one of a series of proteins, expressed by these bacteria in response to stress, that help to regulate Sigma-S, the stationary phase sigma factor of Escherichia coli and Salmonella. IraP is essential for Sigma-S stabilization in some but not all starvation conditions.


Pssm-ID: 431501  Cd Length: 86  Bit Score: 87.40  E-value: 2.28e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2276111379  1 MKNLIAELLVKLAQKEEEAKELTVQVEALEIVVTALLRHMEHDAQQALIQDIEQAIDQVTPC-PPVNDQDAMLLQQYLKK 79
Cdd:pfam10796  1 MKNLISELLIKLAQKEAESKELTAQVEALEILVSALVLTVSKGGQQELIDSIEKAINSVPESsDEILKSDAELLLQNFQR 80


                 ....*.
gi 2276111379 80 LLRHPR 85
Cdd:pfam10796 81 LLTVSR 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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