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Conserved domains on  [gi|358365890|dbj|GAA82512|]
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actin-binding protein [Aspergillus luchuensis IFO 4308]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 9-426 6.68e-86

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member PTZ00421:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 493  Bit Score: 276.00  E-value: 6.68e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890   9 SKYRHVFGRPTRkssQEQCYDNLRVSKNAWD-TNLVKANPKYLSVNWEAGGGGAfaVIPLEERGKLPERIPLFRGHTAVV 87
Cdd:PTZ00421   4 SRFRHTQGVPAR---PDRHFLNVTPSTALWDcSNTIACNDRFIAVPWQQLGSTA--VLKHTDYGKLASNPPILLGQEGPI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  88 LDTDWNPFNDDLIASGSDDGKVFLWRVPENFTLRPDLDPdeiqdvapVGKLSGHPKKIGHVLFNPAAENILATASGDYTV 167
Cdd:PTZ00421  79 IDVAFNPFDPQKLFTASEDGTIMGWGIPEEGLTQNISDP--------IVHLQGHTKKVGIVSFHPSAMNVLASAGADMVV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 168 KIWDIEAGAPKLTL-NLGDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVWLGEHDRIATTG 246
Cdd:PTZ00421 151 NVWDVERGKAVEVIkCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSQRCLWAKRKDLIITLG 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 247 FSKMSDRQLALWDIRAPREPINgFKTLDSISGVCMPFWDEGTQCLYLAGRGDGNIRYFELENDKFEYLAEYKSADPQRGI 326
Cdd:PTZ00421 231 CSKSQQRQIMLWDTRKMASPYS-TVDLDQSSALFIPFFDEDTNLLYIGSKGEGNIRCFELMNERLTFCSSYSSVEPHKGL 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 327 AFMPKRGVNTHDNEVARaFKTVNDGYIEPISFIVPRRA--ETFQDDIYPPTTGLKPAMGPSEWLAGKEAIPPKISMANLY 404
Cdd:PTZ00421 310 CMMPKWSLDTRKCEIAR-FYALTYHSLYTIQMLLPRKQadSELQVDVYPPTFADHPAITADEYFSGGNAEPLVYDMSAVF 388

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 358365890 405 EG-------------EGLKEVTGVQ-DAPTSTMGAS 426
Cdd:PTZ00421 389 DGtspelmgasalspSGKPRHSGVSvPASTSAMTHS 424
flhF super family cl35529
flagellar biosynthesis protein FlhF;
455-585 2.43e-04

flagellar biosynthesis protein FlhF;


The actual alignment was detected with superfamily member PRK06995:

Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 43.80  E-value: 2.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 455 VAKPAPSMKEQGASMAAMVSKFADDEEAETVEEDSSF----EEVQKPVERPARSPEASSPSIKASPWHQKEEEVKTQAAS 530
Cdd:PRK06995  55 AAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAkrltAQREQLVARAAAPAAPEAQAPAAPAERAAAENAARRLAR 134

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 358365890 531 PAKSSPViTPVAAPAdistgAAVAADAVQR------------EIGAIKDLIAEQTKTIASQAQQMQS 585
Cdd:PRK06995 135 AAAAAPR-PRVPADA-----AAAVADAVKArierivndtvmqELRSLRGMLEEQLASLAWGERQRRD 195
 
Name Accession Description Interval E-value
PTZ00421 PTZ00421
coronin; Provisional
 9-426 6.68e-86

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 276.00  E-value: 6.68e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890   9 SKYRHVFGRPTRkssQEQCYDNLRVSKNAWD-TNLVKANPKYLSVNWEAGGGGAfaVIPLEERGKLPERIPLFRGHTAVV 87
Cdd:PTZ00421   4 SRFRHTQGVPAR---PDRHFLNVTPSTALWDcSNTIACNDRFIAVPWQQLGSTA--VLKHTDYGKLASNPPILLGQEGPI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  88 LDTDWNPFNDDLIASGSDDGKVFLWRVPENFTLRPDLDPdeiqdvapVGKLSGHPKKIGHVLFNPAAENILATASGDYTV 167
Cdd:PTZ00421  79 IDVAFNPFDPQKLFTASEDGTIMGWGIPEEGLTQNISDP--------IVHLQGHTKKVGIVSFHPSAMNVLASAGADMVV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 168 KIWDIEAGAPKLTL-NLGDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVWLGEHDRIATTG 246
Cdd:PTZ00421 151 NVWDVERGKAVEVIkCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSQRCLWAKRKDLIITLG 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 247 FSKMSDRQLALWDIRAPREPINgFKTLDSISGVCMPFWDEGTQCLYLAGRGDGNIRYFELENDKFEYLAEYKSADPQRGI 326
Cdd:PTZ00421 231 CSKSQQRQIMLWDTRKMASPYS-TVDLDQSSALFIPFFDEDTNLLYIGSKGEGNIRCFELMNERLTFCSSYSSVEPHKGL 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 327 AFMPKRGVNTHDNEVARaFKTVNDGYIEPISFIVPRRA--ETFQDDIYPPTTGLKPAMGPSEWLAGKEAIPPKISMANLY 404
Cdd:PTZ00421 310 CMMPKWSLDTRKCEIAR-FYALTYHSLYTIQMLLPRKQadSELQVDVYPPTFADHPAITADEYFSGGNAEPLVYDMSAVF 388

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 358365890 405 EG-------------EGLKEVTGVQ-DAPTSTMGAS 426
Cdd:PTZ00421 389 DGtspelmgasalspSGKPRHSGVSvPASTSAMTHS 424
DUF1899 pfam08953
Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic ...
 4-72 8.68e-37

Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic proteins. Function is unknown.


Pssm-ID: 462645 [Multi-domain]  Cd Length: 66  Bit Score: 131.08  E-value: 8.68e-37
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 358365890    4 RFVRSSKYRHVFGRPTRKssqEQCYDNLRVSKNAWDTNLVKANPKYLSVNWEAGGGGAFAVIPLEERGK 72
Cdd:pfam08953   1 RFVRASKFRHVYGKPAKK---ELCYDNIKVTKNAWDSNFIAANPKFLAVNWESSGGGAFAVLPLNQTGR 66
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 80-332 5.02e-28

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 113.97  E-value: 5.02e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  80 FRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWRVPENFTLRpdldpdeiqdvapvgKLSGHPKKIGHVLFNPAAENiLA 159
Cdd:cd00200    5 LKGHTGGVTCVAFSP-DGKLLATGSGDGTIKVWDLETGELLR---------------TLKGHTGPVRDVAASADGTY-LA 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 160 TASGDYTVKIWDIEAGAPKLTLN--LGDiVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVwlG 237
Cdd:cd00200   68 SGSSDKTIRLWDLETGECVRTLTghTSY-VSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAF--S 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 238 EHDRIATTGfskMSDRQLALWDIRAPREpingFKTL----DSISGVCmpfWDEGTQCLYLAGrGDGNIRYFELENDKFEY 313
Cdd:cd00200  145 PDGTFVASS---SQDGTIKLWDLRTGKC----VATLtghtGEVNSVA---FSPDGEKLLSSS-SDGTIKLWDLSTGKCLG 213

                        250
                 ....*....|....*....
gi 358365890 314 LAEYKSaDPQRGIAFMPKR 332
Cdd:cd00200  214 TLRGHE-NGVNSVAFSPDG 231
WD40 COG2319
WD40 repeat [General function prediction only];
75-265 1.84e-26

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 111.93  E-value: 1.84e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  75 ERIPLFRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWRVPENftlrpdldpdeiqdvAPVGKLSGHPKKIGHVLFNPAa 154
Cdd:COG2319  153 KLLRTLTGHSGAVTSVAFSP-DGKLLASGSDDGTVRLWDLATG---------------KLLRTLTGHTGAVRSVAFSPD- 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 155 ENILATASGDYTVKIWDIEAGAPKLTLNL-GDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAknSRS 233
Cdd:COG2319  216 GKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGG--VNS 293

                        170       180       190
                 ....*....|....*....|....*....|...
gi 358365890 234 V-WLGEHDRIATTGfskmSDRQLALWDIRAPRE 265
Cdd:COG2319  294 VaFSPDGKLLASGS----DDGTVRLWDLATGKL 322
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 80-112 3.18e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.23  E-value: 3.18e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 358365890    80 FRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLW 112
Cdd:smart00320   8 LKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLW 39
flhF PRK06995
flagellar biosynthesis protein FlhF;
455-585 2.43e-04

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 43.80  E-value: 2.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 455 VAKPAPSMKEQGASMAAMVSKFADDEEAETVEEDSSF----EEVQKPVERPARSPEASSPSIKASPWHQKEEEVKTQAAS 530
Cdd:PRK06995  55 AAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAkrltAQREQLVARAAAPAAPEAQAPAAPAERAAAENAARRLAR 134

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 358365890 531 PAKSSPViTPVAAPAdistgAAVAADAVQR------------EIGAIKDLIAEQTKTIASQAQQMQS 585
Cdd:PRK06995 135 AAAAAPR-PRVPADA-----AAAVADAVKArierivndtvmqELRSLRGMLEEQLASLAWGERQRRD 195
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 494-567 7.18e-03

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 37.45  E-value: 7.18e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 358365890 494 VQKPVERPARSPEASSPSIKASPW--HQKEEEVKTQAASPAKSSPVITPVAAPADISTGAAVAADAVQreIGAIKD 567
Cdd:COG3147    2 AEEAAAAPAAAAAPAAPAAAAAPApaAAAAAAAPKPAAKPAAPKPAAAAAAAPAAKAAAPAGGGWVVQ--LGAFSN 75
 
Name Accession Description Interval E-value
PTZ00421 PTZ00421
coronin; Provisional
 9-426 6.68e-86

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 276.00  E-value: 6.68e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890   9 SKYRHVFGRPTRkssQEQCYDNLRVSKNAWD-TNLVKANPKYLSVNWEAGGGGAfaVIPLEERGKLPERIPLFRGHTAVV 87
Cdd:PTZ00421   4 SRFRHTQGVPAR---PDRHFLNVTPSTALWDcSNTIACNDRFIAVPWQQLGSTA--VLKHTDYGKLASNPPILLGQEGPI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  88 LDTDWNPFNDDLIASGSDDGKVFLWRVPENFTLRPDLDPdeiqdvapVGKLSGHPKKIGHVLFNPAAENILATASGDYTV 167
Cdd:PTZ00421  79 IDVAFNPFDPQKLFTASEDGTIMGWGIPEEGLTQNISDP--------IVHLQGHTKKVGIVSFHPSAMNVLASAGADMVV 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 168 KIWDIEAGAPKLTL-NLGDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVWLGEHDRIATTG 246
Cdd:PTZ00421 151 NVWDVERGKAVEVIkCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSQRCLWAKRKDLIITLG 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 247 FSKMSDRQLALWDIRAPREPINgFKTLDSISGVCMPFWDEGTQCLYLAGRGDGNIRYFELENDKFEYLAEYKSADPQRGI 326
Cdd:PTZ00421 231 CSKSQQRQIMLWDTRKMASPYS-TVDLDQSSALFIPFFDEDTNLLYIGSKGEGNIRCFELMNERLTFCSSYSSVEPHKGL 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 327 AFMPKRGVNTHDNEVARaFKTVNDGYIEPISFIVPRRA--ETFQDDIYPPTTGLKPAMGPSEWLAGKEAIPPKISMANLY 404
Cdd:PTZ00421 310 CMMPKWSLDTRKCEIAR-FYALTYHSLYTIQMLLPRKQadSELQVDVYPPTFADHPAITADEYFSGGNAEPLVYDMSAVF 388

                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 358365890 405 EG-------------EGLKEVTGVQ-DAPTSTMGAS 426
Cdd:PTZ00421 389 DGtspelmgasalspSGKPRHSGVSvPASTSAMTHS 424
PTZ00420 PTZ00420
coronin; Provisional
 28-405 4.17e-76

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 252.56  E-value: 4.17e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  28 YDNLRVSKNAWDTNLVKANPKYLSVNWEAGGGGAFAVIPLEERGKLPERIPLfRGHTAVVLDTDWNPFNDDLIASGSDDG 107
Cdd:PTZ00420  19 FDDLRICSRVIDSCGIACSSGFVAVPWEVEGGGLIGAIRLENQMRKPPVIKL-KGHTSSILDLQFNPCFSEILASGSEDL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 108 KVFLWRVPENftlrpDLDPDEIQDvaPVGKLSGHPKKIGHVLFNPAAENILATASGDYTVKIWDIEAGAPKLTLNLGDIV 187
Cdd:PTZ00420  98 TIRVWEIPHN-----DESVKEIKD--PQCILKGHKKKISIIDWNPMNYYIMCSSGFDSFVNIWDIENEKRAFQINMPKKL 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 188 QSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVWL----GEHDRIATTGFSKMSDRQLALWDIRAP 263
Cdd:PTZ00420 171 SSLKWNIKGNLLSGTCVGKHMHIIDPRKQEIASSFHIHDGGKNTKNIWIdglgGDDNYILSTGFSKNNMREMKLWDLKNT 250

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 264 REPINGFkTLDSISGVCMPFWDEGTQCLYLAGRGDGNIRYFELENDKFEYLAEYKSADPQRGIAFMPKRGVNTHDNEVAR 343
Cdd:PTZ00420 251 TSALVTM-SIDNASAPLIPHYDESTGLIYLIGKGDGNCRYYQHSLGSIRKVNEYKSCSPFRSFGFLPKQICDVYKCEIGR 329

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 358365890 344 AFKTVNDGYIEPISFIVPRRAET-FQDDIYPPTTGLKPAMGPSEWLAGKEAIPPKISMANLYE 405
Cdd:PTZ00420 330 VYKNENNSSIRPISFYVPRKNPTkFQEDLYPPILMHDPERSSRNWIDGKDNKMKRINIKDLTE 392
DUF1899 pfam08953
Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic ...
 4-72 8.68e-37

Domain of unknown function (DUF1899); This set of domains is found in various eukaryotic proteins. Function is unknown.


Pssm-ID: 462645 [Multi-domain]  Cd Length: 66  Bit Score: 131.08  E-value: 8.68e-37
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 358365890    4 RFVRSSKYRHVFGRPTRKssqEQCYDNLRVSKNAWDTNLVKANPKYLSVNWEAGGGGAFAVIPLEERGK 72
Cdd:pfam08953   1 RFVRASKFRHVYGKPAKK---ELCYDNIKVTKNAWDSNFIAANPKFLAVNWESSGGGAFAVLPLNQTGR 66
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 80-332 5.02e-28

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 113.97  E-value: 5.02e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  80 FRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWRVPENFTLRpdldpdeiqdvapvgKLSGHPKKIGHVLFNPAAENiLA 159
Cdd:cd00200    5 LKGHTGGVTCVAFSP-DGKLLATGSGDGTIKVWDLETGELLR---------------TLKGHTGPVRDVAASADGTY-LA 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 160 TASGDYTVKIWDIEAGAPKLTLN--LGDiVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVwlG 237
Cdd:cd00200   68 SGSSDKTIRLWDLETGECVRTLTghTSY-VSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAF--S 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 238 EHDRIATTGfskMSDRQLALWDIRAPREpingFKTL----DSISGVCmpfWDEGTQCLYLAGrGDGNIRYFELENDKFEY 313
Cdd:cd00200  145 PDGTFVASS---SQDGTIKLWDLRTGKC----VATLtghtGEVNSVA---FSPDGEKLLSSS-SDGTIKLWDLSTGKCLG 213

                        250
                 ....*....|....*....
gi 358365890 314 LAEYKSaDPQRGIAFMPKR 332
Cdd:cd00200  214 TLRGHE-NGVNSVAFSPDG 231
WD40 COG2319
WD40 repeat [General function prediction only];
75-265 1.84e-26

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 111.93  E-value: 1.84e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  75 ERIPLFRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWRVPENftlrpdldpdeiqdvAPVGKLSGHPKKIGHVLFNPAa 154
Cdd:COG2319  153 KLLRTLTGHSGAVTSVAFSP-DGKLLASGSDDGTVRLWDLATG---------------KLLRTLTGHTGAVRSVAFSPD- 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 155 ENILATASGDYTVKIWDIEAGAPKLTLNL-GDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAknSRS 233
Cdd:COG2319  216 GKLLASGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGG--VNS 293

                        170       180       190
                 ....*....|....*....|....*....|...
gi 358365890 234 V-WLGEHDRIATTGfskmSDRQLALWDIRAPRE 265
Cdd:COG2319  294 VaFSPDGKLLASGS----DDGTVRLWDLATGKL 322
WD40 COG2319
WD40 repeat [General function prediction only];
74-261 8.98e-26

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 110.00  E-value: 8.98e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  74 PERIPLFRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWrvpenftlrpDLDPDEiqdvaPVGKLSGHPKKIGHVLFNPA 153
Cdd:COG2319  236 GKLLRTLTGHSGSVRSVAFSP-DGRLLASGSADGTVRLW----------DLATGE-----LLRTLTGHSGGVNSVAFSPD 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 154 AeNILATASGDYTVKIWDIEAGAPKLTLN-LGDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSr 232
Cdd:COG2319  300 G-KLLASGSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTS- 377

                        170       180
                 ....*....|....*....|....*....
gi 358365890 233 SVWLGEHDRIATTGFskmsDRQLALWDIR 261
Cdd:COG2319  378 VAFSPDGRTLASGSA----DGTVRLWDLA 402
WD40 COG2319
WD40 repeat [General function prediction only];
74-330 7.97e-25

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 106.92  E-value: 7.97e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  74 PERIPLFRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWRVpenftlrpdldpdeiQDVAPVGKLSGHPKKIGHVLFNPa 153
Cdd:COG2319  110 GLLLRTLTGHTGAVRSVAFSP-DGKTLASGSADGTVRLWDL---------------ATGKLLRTLTGHSGAVTSVAFSP- 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 154 AENILATASGDYTVKIWDIEAGAPKLTLNL-GDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAknSR 232
Cdd:COG2319  173 DGKLLASGSDDGTVRLWDLATGKLLRTLTGhTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGS--VR 250

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 233 SV-WLGEHDRIATTGfskmSDRQLALWDIRAPREPINGFKTLDSISGVCM-PfwdEGTqclYLA-GRGDGNIRYFELEND 309
Cdd:COG2319  251 SVaFSPDGRLLASGS----ADGTVRLWDLATGELLRTLTGHSGGVNSVAFsP---DGK---LLAsGSDDGTVRLWDLATG 320

                        250       260
                 ....*....|....*....|..
gi 358365890 310 KFeyLAEYK-SADPQRGIAFMP 330
Cdd:COG2319  321 KL--LRTLTgHTGAVRSVAFSP 340
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 80-259 2.22e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 97.41  E-value: 2.22e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  80 FRGHTAVVLDTDWNPFNDdLIASGSDDGKVFLWrvpenftlrpdlDPDEIQdvaPVGKLSGHPKKIGHVLFNPAAENiLA 159
Cdd:cd00200  131 LRGHTDWVNSVAFSPDGT-FVASSSQDGTIKLW------------DLRTGK---CVATLTGHTGEVNSVAFSPDGEK-LL 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 160 TASGDYTVKIWDIEAGAPKLTLNL-GDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSrSVWLGE 238
Cdd:cd00200  194 SSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTS-LAWSPD 272

                        170       180
                 ....*....|....*....|.
gi 358365890 239 HDRIATTGFskmsDRQLALWD 259
Cdd:cd00200  273 GKRLASGSA----DGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
74-265 3.35e-22

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 99.22  E-value: 3.35e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  74 PERIPLFRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWRVPENFTLRPdldpdeiqdvapvgkLSGHPKKIGHVLFNPA 153
Cdd:COG2319   68 GALLATLLGHTAAVLSVAFSP-DGRLLASASADGTVRLWDLATGLLLRT---------------LTGHTGAVRSVAFSPD 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 154 AEnILATASGDYTVKIWDIEAGAPKLTLNL-GDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSr 232
Cdd:COG2319  132 GK-TLASGSADGTVRLWDLATGKLLRTLTGhSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRS- 209

                        170       180       190
                 ....*....|....*....|....*....|...
gi 358365890 233 SVWLGEHDRIATTGfskmSDRQLALWDIRAPRE 265
Cdd:COG2319  210 VAFSPDGKLLASGS----ADGTVRLWDLATGKL 238
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 134-311 1.81e-19

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 88.93  E-value: 1.81e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 134 PVGKLSGHPKKIGHVLFNPaAENILATASGDYTVKIWDIEAGAPKLTL-NLGDIVQSQSWSANGSLLVTTSRDKKLRIWD 212
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSP-DGKLLATGSGDGTIKVWDLETGELLRTLkGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 213 VRQERPAHETQGHSGAKNSrSVWLgEHDRIATTGfskMSDRQLALWDIRAPREpingFKTLDSISG-VCMPFWDEGTQcL 291
Cdd:cd00200   80 LETGECVRTLTGHTSYVSS-VAFS-PDGRILSSS---SRDKTIKVWDVETGKC----LTTLRGHTDwVNSVAFSPDGT-F 149

                        170       180
                 ....*....|....*....|
gi 358365890 292 YLAGRGDGNIRYFELENDKF 311
Cdd:cd00200  150 VASSSQDGTIKLWDLRTGKC 169
WD40_4 pfam16300
Type of WD40 repeat; Most members of this family form part of the 7-bladed beta-propeller at ...
 353-395 2.25e-17

Type of WD40 repeat; Most members of this family form part of the 7-bladed beta-propeller at the N-terminus of coronin proteins.


Pssm-ID: 465087 [Multi-domain]  Cd Length: 44  Bit Score: 75.63  E-value: 2.25e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 358365890  353 IEPISFIVPRRA-ETFQDDIYPPTTGLKPAMGPSEWLAGKEAIP 395
Cdd:pfam16300   1 IEPISFTVPRKSkEDFQDDLYPDTAGTEPALTAEEWLSGKNAEP 44
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 79-171 6.93e-09

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 57.34  E-value: 6.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  79 LFRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLWrvpenftlrpDLDPDEiqdvaPVGKLSGHPKKIGHVLFNPAAeNIL 158
Cdd:cd00200  214 TLRGHENGVNSVAFSP-DGYLLASGSEDGTIRVW----------DLRTGE-----CVQTLSGHTNSVTSLAWSPDG-KRL 276

                         90
                 ....*....|...
gi 358365890 159 ATASGDYTVKIWD 171
Cdd:cd00200  277 ASGSADGTIRIWD 289
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 83-306 3.88e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 56.25  E-value: 3.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  83 HTAVVLDTDWNPFNDDLIASGSDDGKVFLWRVPENFTLrpdldpDEIQDVApvgklsghpkKIGHVLFNPAAENILATAS 162
Cdd:PLN00181 574 HEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSI------GTIKTKA----------NICCVQFPSESGRSLAFGS 637

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 163 GDYTVKIWDIEagAPKLTLnLGDIVQSQSWS----ANGSLLVTTSRDKKLRIWDVR------QERPAHETQGHSGAKNsr 232
Cdd:PLN00181 638 ADHKVYYYDLR--NPKLPL-CTMIGHSKTVSyvrfVDSSTLVSSSTDNTLKLWDLSmsisgiNETPLHSFMGHTNVKN-- 712

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 233 SVWLGEHDRIATTGfskmSDRQLALWDIRAPREPING--FKTLDSISG------------VCmpfWdEGTQCLYLAGRGD 298
Cdd:PLN00181 713 FVGLSVSDGYIATG----SETNEVFVYHKAFPMPVLSykFKTIDPVSGlevddasqfissVC---W-RGQSSTLVAANST 784


                 ....*...
gi 358365890 299 GNIRYFEL 306
Cdd:PLN00181 785 GNIKILEM 792
WD40 COG2319
WD40 repeat [General function prediction only];
130-310 4.71e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 55.69  E-value: 4.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 130 QDVAPVGKLSGHPKKIGHVLFNPAAEnILATASGDYTVKIWDIEAGAPKLTLNLG-DIVQSQSWSANGSLLVTTSRDKKL 208
Cdd:COG2319   24 ALGALLLLLLGLAAAVASLAASPDGA-RLAAGAGDLTLLLLDAAAGALLATLLGHtAAVLSVAFSPDGRLLASASADGTV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 209 RIWDVRQERPAHETQGHSGAKNSRSvWLGEHDRIATTGfskmSDRQLALWDIRAPREPingfKTL----DSISGVCmpFW 284
Cdd:COG2319  103 RLWDLATGLLLRTLTGHTGAVRSVA-FSPDGKTLASGS----ADGTVRLWDLATGKLL----RTLtghsGAVTSVA--FS 171

                        170       180
                 ....*....|....*....|....*..
gi 358365890 285 DEGTqclYLA-GRGDGNIRYFELENDK 310
Cdd:COG2319  172 PDGK---LLAsGSDDGTVRLWDLATGK 195
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 92-268 6.78e-07

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 52.40  E-value: 6.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  92 WNPFNDDLIASGSDDGKVFLWRVPENftlrpdldpdeiqdvAPVGKLSGHPKKIGHVLFNPAAENILATASGDYTVKIWD 171
Cdd:PLN00181 540 WNSYIKSQVASSNFEGVVQVWDVARS---------------QLVTEMKEHEKRVWSIDYSSADPTLLASGSDDGSVKLWS 604

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 172 IEAGAPKLTLNL-GDIVQSQSWSANGSLLVTTSRDKKLRIWDVRQER-PAHETQGHSgaKNSRSVWLGEhdriATTGFSK 249
Cdd:PLN00181 605 INQGVSIGTIKTkANICCVQFPSESGRSLAFGSADHKVYYYDLRNPKlPLCTMIGHS--KTVSYVRFVD----SSTLVSS 678

                        170
                 ....*....|....*....
gi 358365890 250 MSDRQLALWDIRAPREPIN 268
Cdd:PLN00181 679 STDNTLKLWDLSMSISGIN 697
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 80-112 3.18e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.23  E-value: 3.18e-06
                           10        20        30
                   ....*....|....*....|....*....|...
gi 358365890    80 FRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLW 112
Cdd:smart00320   8 LKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLW 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 134-171 1.36e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.30  E-value: 1.36e-05
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 358365890   134 PVGKLSGHPKKIGHVLFNPAaENILATASGDYTVKIWD 171
Cdd:smart00320   4 LLKTLKGHTGPVTSVAFSPD-GKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
80-112 2.11e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.56  E-value: 2.11e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 358365890   80 FRGHTAVVLDTDWNPfNDDLIASGSDDGKVFLW 112
Cdd:pfam00400   7 LEGHTGSVTSLAFSP-DGKLLASGSDDGTVKVW 38
WD40 pfam00400
WD domain, G-beta repeat;
134-171 6.98e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 6.98e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 358365890  134 PVGKLSGHPKKIGHVLFNPAaENILATASGDYTVKIWD 171
Cdd:pfam00400   3 LLKTLEGHTGSVTSLAFSPD-GKLLASGSDDGTVKVWD 39
flhF PRK06995
flagellar biosynthesis protein FlhF;
455-585 2.43e-04

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 43.80  E-value: 2.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 455 VAKPAPSMKEQGASMAAMVSKFADDEEAETVEEDSSF----EEVQKPVERPARSPEASSPSIKASPWHQKEEEVKTQAAS 530
Cdd:PRK06995  55 AAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAkrltAQREQLVARAAAPAAPEAQAPAAPAERAAAENAARRLAR 134

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 358365890 531 PAKSSPViTPVAAPAdistgAAVAADAVQR------------EIGAIKDLIAEQTKTIASQAQQMQS 585
Cdd:PRK06995 135 AAAAAPR-PRVPADA-----AAAVADAVKArierivndtvmqELRSLRGMLEEQLASLAWGERQRRD 195
WD40 pfam00400
WD domain, G-beta repeat;
185-212 7.40e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 37.32  E-value: 7.40e-04
                          10        20
                  ....*....|....*....|....*...
gi 358365890  185 DIVQSQSWSANGSLLVTTSRDKKLRIWD 212
Cdd:pfam00400  12 GSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 191-212 9.90e-04

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 36.91  E-value: 9.90e-04
                           10        20
                   ....*....|....*....|..
gi 358365890   191 SWSANGSLLVTTSRDKKLRIWD 212
Cdd:smart00320  19 AFSPDGKYLASGSDDGTIKLWD 40
WD40 COG2319
WD40 repeat [General function prediction only];
158-279 1.81e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 41.05  E-value: 1.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890 158 LATASGDYTVKIWDIEAGAPKLTLNLG-DIVQSQSWSANGSLLVTTSRDKKLRIWDVRQERPAHETQGHSGAKNSRSVWL 236
Cdd:COG2319    9 LAAASADLALALLAAALGALLLLLLGLaAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSP 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 358365890 237 GEHdRIATTGfskmSDRQLALWDIRAPREPINGFKTLDSISGV 279
Cdd:COG2319   89 DGR-LLASAS----ADGTVRLWDLATGLLLRTLTGHTGAVRSV 126
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 117-218 2.12e-03

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 40.83  E-value: 2.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 358365890  117 NFTLRPDLDPD-EI-QDVAPvgklsghPKKIGhvlfNPAAENI---------LATASGDYTVKIWDIEAGAPKLTLNLGD 185
Cdd:pfam20426  47 NFTFSGSQDPFfGIgSDVLS-------PRKIG----SPLAENVelgaqcfatLQTPSENFLISCGNWENSFQVISLNDGR 115

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 358365890  186 IVQSQ----------SWSANGSLLVTTSRDKKLRIWDVRQERP 218
Cdd:pfam20426 116 MVQSIrqhkdvvscvAVTSDGSILATGSYDTTVMVWEVLRGRS 158
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 494-567 7.18e-03

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 37.45  E-value: 7.18e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 358365890 494 VQKPVERPARSPEASSPSIKASPW--HQKEEEVKTQAASPAKSSPVITPVAAPADISTGAAVAADAVQreIGAIKD 567
Cdd:COG3147    2 AEEAAAAPAAAAAPAAPAAAAAPApaAAAAAAAPKPAAKPAAPKPAAAAAAAPAAKAAAPAGGGWVVQ--LGAFSN 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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