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Conserved domains on  [gi|358339740|dbj|GAA47741|]
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ccr4-not transcription complex [Clonorchis sinensis]

Protein Classification

zf-CCCH_3 and ZnF_C3H1 domain-containing protein( domain architecture ID 11788354)

zf-CCCH_3 and ZnF_C3H1 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_C3H1 smart00356
zinc finger;
960-980 6.76e-05

zinc finger;


:

Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 40.69  E-value: 6.76e-05
                           10        20
                   ....*....|....*....|.
gi 358339740   960 CKFWEMGECFKGPTCPFLHGY 980
Cdd:smart00356   7 CKFFKRGYCPRGDRCKFAHPL 27
zf-CCCH_3 super family cl25863
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
 936-978 5.62e-03

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


The actual alignment was detected with superfamily member pfam15663:

Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 37.44  E-value: 5.62e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 358339740  936 CSFYLRGHCKKED-CEFAHDLT----KVTCKFWEMGECFKgPTCPFLH 978
Cdd:pfam15663   8 CYFFYYSTCTKGDsCPFRHCEAalgnETVCTLWQEGRCFR-PVCRFRH 54
 
Name Accession Description Interval E-value
ZnF_C3H1 smart00356
zinc finger;
960-980 6.76e-05

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 40.69  E-value: 6.76e-05
                           10        20
                   ....*....|....*....|.
gi 358339740   960 CKFWEMGECFKGPTCPFLHGY 980
Cdd:smart00356   7 CKFFKRGYCPRGDRCKFAHPL 27
zf-CCCH_3 pfam15663
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
 936-978 5.62e-03

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 37.44  E-value: 5.62e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 358339740  936 CSFYLRGHCKKED-CEFAHDLT----KVTCKFWEMGECFKgPTCPFLH 978
Cdd:pfam15663   8 CYFFYYSTCTKGDsCPFRHCEAalgnETVCTLWQEGRCFR-PVCRFRH 54
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 960-978 8.66e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 34.70  E-value: 8.66e-03
                          10
                  ....*....|....*....
gi 358339740  960 CKFWEMGECFKGPTCPFLH 978
Cdd:pfam18345   1 CKFFLKGRCRYGDKCRFAH 19
 
Name Accession Description Interval E-value
ZnF_C3H1 smart00356
zinc finger;
960-980 6.76e-05

zinc finger;


Pssm-ID: 214632 [Multi-domain]  Cd Length: 27  Bit Score: 40.69  E-value: 6.76e-05
                           10        20
                   ....*....|....*....|.
gi 358339740   960 CKFWEMGECFKGPTCPFLHGY 980
Cdd:smart00356   7 CKFFKRGYCPRGDRCKFAHPL 27
zf-CCCH_3 pfam15663
Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically ...
 936-978 5.62e-03

Zinc-finger containing family; zf-CCCH_3 family is found in eukaryotes, and is typically between 155 and 169 amino acids in length.


Pssm-ID: 464787 [Multi-domain]  Cd Length: 110  Bit Score: 37.44  E-value: 5.62e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 358339740  936 CSFYLRGHCKKED-CEFAHDLT----KVTCKFWEMGECFKgPTCPFLH 978
Cdd:pfam15663   8 CYFFYYSTCTKGDsCPFRHCEAalgnETVCTLWQEGRCFR-PVCRFRH 54
zf_CCCH_4 pfam18345
Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch ...
 960-978 8.66e-03

Zinc finger domain; This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.


Pssm-ID: 465719 [Multi-domain]  Cd Length: 19  Bit Score: 34.70  E-value: 8.66e-03
                          10
                  ....*....|....*....
gi 358339740  960 CKFWEMGECFKGPTCPFLH 978
Cdd:pfam18345   1 CKFFLKGRCRYGDKCRFAH 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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