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Conserved domains on  [gi|589469555|gb|EXH51377|]
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transglycosylase SLT domain protein [Acinetobacter baumannii 1412924]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ddrB-ParB pfam18763
ddrB-like ParB superfamily domain; A member of the ParB/sulfiredoxin superfamily of proteins ...
 531-661 1.18e-47

ddrB-like ParB superfamily domain; A member of the ParB/sulfiredoxin superfamily of proteins found in polyvalent proteins prototyped by the version in the phage P1 ddRB protein. These proteins are predicted to function as nucleases.


:

Pssm-ID: 436719 [Multi-domain]  Cd Length: 122  Bit Score: 165.53  E-value: 1.18e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589469555  531 MDGSSYDFAYEVKDWTDLVASNDQlygvnplypsELQPRDRTREASRQQIERMADDLKPELLGESYKLSDGAPIIGPDNV 610
Cdd:pfam18763   1 DDGRIVDVDYVVVDADDLKPSFDA----------ELQPRDRSRAASEEQIEEIAANLDPELLGDSPGASDGAPIVGKDGV 70

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 589469555  611 VESGNGRTLAIGRAYDNGRADAYREFVQNWANSRGMD-ISGLNQPVLVRTRL 661
Cdd:pfam18763  71 VESGNGRTMALRRAYEEGSADAYRQALKENAAEFGLDqIEGMDDPVLVRRRK 122
Lyz-like super family cl00222
lysozyme-like domains; This family contains several members, including soluble lytic ...
 385-432 4.36e-03

lysozyme-like domains; This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides.


The actual alignment was detected with superfamily member cd13925:

Pssm-ID: 469668 [Multi-domain]  Cd Length: 71  Bit Score: 36.59  E-value: 4.36e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 589469555 385 ETGGkfNHTAQNPTSSAYGLFQVLDDSWKNLGGKDRNNV---DEQIRIGLK 432
Cdd:cd13925   10 ESGG--NWNAVNTGNGYYGGLQFLQGTWKSVGGLGYPDDatrAEQITRAER 58
 
Name Accession Description Interval E-value
ddrB-ParB pfam18763
ddrB-like ParB superfamily domain; A member of the ParB/sulfiredoxin superfamily of proteins ...
 531-661 1.18e-47

ddrB-like ParB superfamily domain; A member of the ParB/sulfiredoxin superfamily of proteins found in polyvalent proteins prototyped by the version in the phage P1 ddRB protein. These proteins are predicted to function as nucleases.


Pssm-ID: 436719 [Multi-domain]  Cd Length: 122  Bit Score: 165.53  E-value: 1.18e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589469555  531 MDGSSYDFAYEVKDWTDLVASNDQlygvnplypsELQPRDRTREASRQQIERMADDLKPELLGESYKLSDGAPIIGPDNV 610
Cdd:pfam18763   1 DDGRIVDVDYVVVDADDLKPSFDA----------ELQPRDRSRAASEEQIEEIAANLDPELLGDSPGASDGAPIVGKDGV 70

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 589469555  611 VESGNGRTLAIGRAYDNGRADAYREFVQNWANSRGMD-ISGLNQPVLVRTRL 661
Cdd:pfam18763  71 VESGNGRTMALRRAYEEGSADAYRQALKENAAEFGLDqIEGMDDPVLVRRRK 122
RPF cd13925
core lysozyme-like domain of resuscitation-promoting factor proteins; Resuscitation-promoting ...
 385-432 4.36e-03

core lysozyme-like domain of resuscitation-promoting factor proteins; Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.


Pssm-ID: 381607 [Multi-domain]  Cd Length: 71  Bit Score: 36.59  E-value: 4.36e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 589469555 385 ETGGkfNHTAQNPTSSAYGLFQVLDDSWKNLGGKDRNNV---DEQIRIGLK 432
Cdd:cd13925   10 ESGG--NWNAVNTGNGYYGGLQFLQGTWKSVGGLGYPDDatrAEQITRAER 58
 
Name Accession Description Interval E-value
ddrB-ParB pfam18763
ddrB-like ParB superfamily domain; A member of the ParB/sulfiredoxin superfamily of proteins ...
 531-661 1.18e-47

ddrB-like ParB superfamily domain; A member of the ParB/sulfiredoxin superfamily of proteins found in polyvalent proteins prototyped by the version in the phage P1 ddRB protein. These proteins are predicted to function as nucleases.


Pssm-ID: 436719 [Multi-domain]  Cd Length: 122  Bit Score: 165.53  E-value: 1.18e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589469555  531 MDGSSYDFAYEVKDWTDLVASNDQlygvnplypsELQPRDRTREASRQQIERMADDLKPELLGESYKLSDGAPIIGPDNV 610
Cdd:pfam18763   1 DDGRIVDVDYVVVDADDLKPSFDA----------ELQPRDRSRAASEEQIEEIAANLDPELLGDSPGASDGAPIVGKDGV 70

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 589469555  611 VESGNGRTLAIGRAYDNGRADAYREFVQNWANSRGMD-ISGLNQPVLVRTRL 661
Cdd:pfam18763  71 VESGNGRTMALRRAYEEGSADAYRQALKENAAEFGLDqIEGMDDPVLVRRRK 122
RPF cd13925
core lysozyme-like domain of resuscitation-promoting factor proteins; Resuscitation-promoting ...
 385-432 4.36e-03

core lysozyme-like domain of resuscitation-promoting factor proteins; Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.


Pssm-ID: 381607 [Multi-domain]  Cd Length: 71  Bit Score: 36.59  E-value: 4.36e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 589469555 385 ETGGkfNHTAQNPTSSAYGLFQVLDDSWKNLGGKDRNNV---DEQIRIGLK 432
Cdd:cd13925   10 ESGG--NWNAVNTGNGYYGGLQFLQGTWKSVGGLGYPDDatrAEQITRAER 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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