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Conserved domains on  [gi|585105330|gb|EWM24040|]
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Poly A polymerase, head domain protein [Nannochloropsis gaditana]

Protein Classification

tRNA nucleotidyltransferase/poly(A) polymerase family protein( domain architecture ID 1904300)

tRNA nucleotidyltransferase/poly(A) polymerase family protein, such as CC-adding tRNA nucleotidyltransferase, which is involved in the process of adding nucleotides to the 3' end of transfer RNA (tRNA) molecules

CATH:  3.30.460.10
EC:  2.7.7.-
Gene Ontology:  GO:0008033|GO:0000166|GO:0046872|GO:0016779|GO:0000049
PubMed:  3009457|10075991

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PcnB super family cl43211
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ...
 190-409 1.33e-39

tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification


The actual alignment was detected with superfamily member COG0617:

Pssm-ID: 440382 [Multi-domain]  Cd Length: 391  Bit Score: 145.73  E-value: 1.33e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 190 RLFKTMLAVVKD-ENLGTTLRVAGGWVRDKVLGHwsadgEV-DIDIALDNLmGSDFAAMLNGWLAKRgrqvyNVGIisan 267
Cdd:COG0617    1 RLSPNALKVLEAlEEAGFEAYLVGGAVRDLLLGR-----PPkDIDIVTVAT-PEEVAALFRKALRTV-----PVGR---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 268 ptksKHLeTATMRVGSFSIDFVNLRTEAYTDESRIPS--MGiGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMR 345
Cdd:COG0617   66 ----DFG-TVTVVFGGEKIEVATARTERYYGDGRRPFveFG-DTLEEDLARRDFTINALAYDLNDGELIDPFG-GLADLE 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585105330 346 EGVIRTPLPALTTLLDDPLRVLRAVRFASRLAFSISDELVVAASDprvHGALAHKVSRERIGSE 409
Cdd:COG0617  139 ARVIRTVGDPEERFREDPLRILRAVRFAARLGFTIEPETLAAIRE---MAGLLDRLSAERVWDE 199
 
Name Accession Description Interval E-value
PcnB COG0617
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ...
 190-409 1.33e-39

tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440382 [Multi-domain]  Cd Length: 391  Bit Score: 145.73  E-value: 1.33e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 190 RLFKTMLAVVKD-ENLGTTLRVAGGWVRDKVLGHwsadgEV-DIDIALDNLmGSDFAAMLNGWLAKRgrqvyNVGIisan 267
Cdd:COG0617    1 RLSPNALKVLEAlEEAGFEAYLVGGAVRDLLLGR-----PPkDIDIVTVAT-PEEVAALFRKALRTV-----PVGR---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 268 ptksKHLeTATMRVGSFSIDFVNLRTEAYTDESRIPS--MGiGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMR 345
Cdd:COG0617   66 ----DFG-TVTVVFGGEKIEVATARTERYYGDGRRPFveFG-DTLEEDLARRDFTINALAYDLNDGELIDPFG-GLADLE 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585105330 346 EGVIRTPLPALTTLLDDPLRVLRAVRFASRLAFSISDELVVAASDprvHGALAHKVSRERIGSE 409
Cdd:COG0617  139 ARVIRTVGDPEERFREDPLRILRAVRFAARLGFTIEPETLAAIRE---MAGLLDRLSAERVWDE 199
NT_ClassII-CCAase cd05398
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ...
 202-346 5.47e-37

Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.


Pssm-ID: 143388 [Multi-domain]  Cd Length: 139  Bit Score: 131.56  E-value: 5.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 202 ENLGTTLRVAGGWVRDKVLGHWSADgevdIDIALDNlMGSDFAAMLNgwlakrgrQVYNVGIISANptksKHLETATMRV 281
Cdd:cd05398   13 KALGYEAYLVGGAVRDLLLGRPPKD----IDIATDA-DGPEFAEALF--------KKIGGRVVGLG----EEFGTATVVI 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 585105330 282 GSFSIDFVNLRTEAYTDESRIPSMGIGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMRE 346
Cdd:cd05398   76 NGLTIDVATLRTETYTDPGRRPPVVGFTIEEDLLRRDFTINAMAYDLDDGELIDPFG-GLKDLEN 139
PolyA_pol pfam01743
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ...
 208-350 9.16e-31

Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.


Pssm-ID: 396348 [Multi-domain]  Cd Length: 126  Bit Score: 114.30  E-value: 9.16e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330  208 LRVAGGWVRDKVLGHWSADgevdIDIALD---NLMGSDFAAMLNGWLAKrGRQVYNVGIISANPTkskhLETATMRVGSF 284
Cdd:pfam01743   1 LYIVGGAVRDLLLGKTPKD----VDIATDatpEQVATLFRRRRIVHLLS-GIEFGTIHVIFGNQI----LEVATFRIEFD 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585105330  285 SIDFVNLRTEAYTdesripsmgiGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMREGVIR 350
Cdd:pfam01743  72 ESDFRNPRSEEYT----------GTLEEDAKRRDFTINALAYNPNSGEVIDYFG-GIKDLKSGVIR 126
PRK13299 PRK13299
tRNA CCA-pyrophosphorylase; Provisional
 292-406 1.28e-17

tRNA CCA-pyrophosphorylase; Provisional


Pssm-ID: 237339 [Multi-domain]  Cd Length: 394  Bit Score: 84.12  E-value: 1.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 292 RTEA-YTDESRiPS--MGIGSPEEDAMRRDLTINALFYNLHtGQIEDFCGrGLRDMREGVIRTPLPALTTLLDDPLRVLR 368
Cdd:PRK13299  85 RTESeYVDYRR-PSevTFVRSLEEDLKRRDFTINAIAMDEN-GEIIDLFD-GLEDLKNRLIRAVGNAEERFQEDALRMMR 161

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 585105330 369 AVRFASRLAFSISDELVVAASDprvHGALAHKVSRERI 406
Cdd:PRK13299 162 AVRFASQLGFDLETETFEAMKT---QAPLLEKISVERI 196
pcnB TIGR01942
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ...
 308-383 2.98e-16

poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).


Pssm-ID: 130997 [Multi-domain]  Cd Length: 410  Bit Score: 79.84  E-value: 2.98e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585105330  308 GSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMREGVIRTPLPALTTLLDDPLRVLRAVRFASRLAFSISDE 383
Cdd:TIGR01942 114 GTLEEDAWRRDFTVNALYYDPSREVIIDYVG-GMEDLKNRRLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDES 188
 
Name Accession Description Interval E-value
PcnB COG0617
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ...
 190-409 1.33e-39

tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440382 [Multi-domain]  Cd Length: 391  Bit Score: 145.73  E-value: 1.33e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 190 RLFKTMLAVVKD-ENLGTTLRVAGGWVRDKVLGHwsadgEV-DIDIALDNLmGSDFAAMLNGWLAKRgrqvyNVGIisan 267
Cdd:COG0617    1 RLSPNALKVLEAlEEAGFEAYLVGGAVRDLLLGR-----PPkDIDIVTVAT-PEEVAALFRKALRTV-----PVGR---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 268 ptksKHLeTATMRVGSFSIDFVNLRTEAYTDESRIPS--MGiGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMR 345
Cdd:COG0617   66 ----DFG-TVTVVFGGEKIEVATARTERYYGDGRRPFveFG-DTLEEDLARRDFTINALAYDLNDGELIDPFG-GLADLE 138

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585105330 346 EGVIRTPLPALTTLLDDPLRVLRAVRFASRLAFSISDELVVAASDprvHGALAHKVSRERIGSE 409
Cdd:COG0617  139 ARVIRTVGDPEERFREDPLRILRAVRFAARLGFTIEPETLAAIRE---MAGLLDRLSAERVWDE 199
NT_ClassII-CCAase cd05398
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ...
 202-346 5.47e-37

Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.


Pssm-ID: 143388 [Multi-domain]  Cd Length: 139  Bit Score: 131.56  E-value: 5.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 202 ENLGTTLRVAGGWVRDKVLGHWSADgevdIDIALDNlMGSDFAAMLNgwlakrgrQVYNVGIISANptksKHLETATMRV 281
Cdd:cd05398   13 KALGYEAYLVGGAVRDLLLGRPPKD----IDIATDA-DGPEFAEALF--------KKIGGRVVGLG----EEFGTATVVI 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 585105330 282 GSFSIDFVNLRTEAYTDESRIPSMGIGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMRE 346
Cdd:cd05398   76 NGLTIDVATLRTETYTDPGRRPPVVGFTIEEDLLRRDFTINAMAYDLDDGELIDPFG-GLKDLEN 139
PolyA_pol pfam01743
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ...
 208-350 9.16e-31

Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.


Pssm-ID: 396348 [Multi-domain]  Cd Length: 126  Bit Score: 114.30  E-value: 9.16e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330  208 LRVAGGWVRDKVLGHWSADgevdIDIALD---NLMGSDFAAMLNGWLAKrGRQVYNVGIISANPTkskhLETATMRVGSF 284
Cdd:pfam01743   1 LYIVGGAVRDLLLGKTPKD----VDIATDatpEQVATLFRRRRIVHLLS-GIEFGTIHVIFGNQI----LEVATFRIEFD 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585105330  285 SIDFVNLRTEAYTdesripsmgiGSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMREGVIR 350
Cdd:pfam01743  72 ESDFRNPRSEEYT----------GTLEEDAKRRDFTINALAYNPNSGEVIDYFG-GIKDLKSGVIR 126
PRK13299 PRK13299
tRNA CCA-pyrophosphorylase; Provisional
 292-406 1.28e-17

tRNA CCA-pyrophosphorylase; Provisional


Pssm-ID: 237339 [Multi-domain]  Cd Length: 394  Bit Score: 84.12  E-value: 1.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 292 RTEA-YTDESRiPS--MGIGSPEEDAMRRDLTINALFYNLHtGQIEDFCGrGLRDMREGVIRTPLPALTTLLDDPLRVLR 368
Cdd:PRK13299  85 RTESeYVDYRR-PSevTFVRSLEEDLKRRDFTINAIAMDEN-GEIIDLFD-GLEDLKNRLIRAVGNAEERFQEDALRMMR 161

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 585105330 369 AVRFASRLAFSISDELVVAASDprvHGALAHKVSRERI 406
Cdd:PRK13299 162 AVRFASQLGFDLETETFEAMKT---QAPLLEKISVERI 196
pcnB PRK11623
poly(A) polymerase I; Provisional
 308-409 2.89e-17

poly(A) polymerase I; Provisional


Pssm-ID: 236939 [Multi-domain]  Cd Length: 472  Bit Score: 83.26  E-value: 2.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 308 GSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMREGVIRTPLPALTTLLDDPLRVLRAVRFASRLAFSISDElvVA 387
Cdd:PRK11623 159 GSIEEDAQRRDFTINSLYYSVADFTVRDYVG-GMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPE--TA 235

                         90       100
                 ....*....|....*....|..
gi 585105330 388 ASDPRVhGALAHKVSRERIGSE 409
Cdd:PRK11623 236 EPIPRL-ATLLNDIPPARLFEE 256
pcnB TIGR01942
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ...
 308-383 2.98e-16

poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).


Pssm-ID: 130997 [Multi-domain]  Cd Length: 410  Bit Score: 79.84  E-value: 2.98e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585105330  308 GSPEEDAMRRDLTINALFYNLHTGQIEDFCGrGLRDMREGVIRTPLPALTTLLDDPLRVLRAVRFASRLAFSISDE 383
Cdd:TIGR01942 114 GTLEEDAWRRDFTVNALYYDPSREVIIDYVG-GMEDLKNRRLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDES 188
cca PRK10885
multifunctional CCA addition/repair protein;
311-383 2.95e-13

multifunctional CCA addition/repair protein;


Pssm-ID: 182810 [Multi-domain]  Cd Length: 409  Bit Score: 70.65  E-value: 2.95e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585105330 311 EEDAMRRDLTINALFYNLHtGQIEDFCGrGLRDMREGVIRTPLPALTtllDDPLRVLRAVRFASRLA---FSISDE 383
Cdd:PRK10885  85 EEDLIRRDLTINAMAQDDD-GELIDPYG-GQRDLEARLLRHVSPAFA---EDPLRVLRVARFAARFAhlgFRIAPE 155
PRK13298 PRK13298
tRNA CCA-pyrophosphorylase; Provisional
 311-383 1.48e-11

tRNA CCA-pyrophosphorylase; Provisional


Pssm-ID: 237338 [Multi-domain]  Cd Length: 417  Bit Score: 65.52  E-value: 1.48e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585105330 311 EEDAMRRDLTINALFYNLHTGQIEDFCGRglRDMREGVIRTPLPALTtllDDPLRVLRAVRFASRLA---FSISDE 383
Cdd:PRK13298  85 EEDLIRRDLTINAIAQDENGNYIDPFQGK--KDIQLRLLRHVSESFI---EDPLRVLRVARFAALLVhlgFKIAKE 155
PRK13296 PRK13296
CCA tRNA nucleotidyltransferase;
311-416 2.01e-08

CCA tRNA nucleotidyltransferase;


Pssm-ID: 106256 [Multi-domain]  Cd Length: 360  Bit Score: 55.76  E-value: 2.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585105330 311 EEDAMRRDLTINALFYNLHTGQIEDFCGRGlrDMREGVIRTPLPAlttLLDDPLRVLRAVRFASRLA---FSISDELVVA 387
Cdd:PRK13296  85 EDDLKRRDLTINSIAIDQNNKVIDPFNGQA--DLQNRILRHTSIA---FIEDPLRVVRLARFKAQLSnfnFSIAQEMLAL 159

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 585105330 388 ASDPRVHGALAHkVSRERIGSE--------KRFFPSL 416
Cdd:PRK13296 160 IKELVKTGELNH-LTRERLHIEfvkalnnpKIFFTTL 195
PRK13297 PRK13297
tRNA CCA-pyrophosphorylase; Provisional
 311-383 1.46e-04

tRNA CCA-pyrophosphorylase; Provisional


Pssm-ID: 139469 [Multi-domain]  Cd Length: 364  Bit Score: 43.83  E-value: 1.46e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585105330 311 EEDAMRRDLTINALfYNLHTGQIEDFCGrGLRDMREGVIRTPLPALTtllDDPLRVLRAVRFASRLA-FSISDE 383
Cdd:PRK13297  96 EQDLQRRDLTVNAI-ARTPQGELVDPLD-GVADVRARVLRHVGEAFA---EDPVRILRLGRFAARFGdFSIAPE 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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