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Conserved domains on  [gi|577034337|gb|EUC76982|]
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glucan-binding protein C, partial [Streptococcus sp. CM7]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Streccoc_I_II super family cl41447
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ...
 1-542 0e+00

antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.


The actual alignment was detected with superfamily member NF033804:

Pssm-ID: 468188 [Multi-domain]  Cd Length: 1552  Bit Score: 905.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337    1 AKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAAVKKANADNEADYQAKLAAYQTELARVQKAN 80
Cdd:NF033804  328 AKAAYEKAVEENTAKNTAIQAENEAIKQRNAAAKATYEAALKQYEADLAAVKKANAANEADYQAKLAAYQTELARVQKAN 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   81 AEAKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAKYQKDLAEYPSKLKAYEDEQAAIKAALAE 160
Cdd:NF033804  408 ADAKAAYEKAVEDNKAKNAALQAENEAIKQRNAAAKADYEAKLAKYQADLAKYKKDLAEYPAKLKAYEDEQAKIKAALAE 487

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  161 LEKHKNEDGNLTEPSAQSLVYDLEPNANLSLTTNGKFLKASAVDDAFSKSTSKgkYDQKILQLDDLDISNLEQVDDVASS 240
Cdd:NF033804  488 LEKKKNEDGYLSEPSAQSLVYDSEPNAQLSLTTDGKLLKASAVDEAFKKDTAQ--YGKKNLQLDNLNVTNLEQADATTSS 565

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  241 MELYGNFGTKAGWTTTVSSSGVAKWGSVLLERGQSATATYTNLQNSYYNGKKISKIVYKYTVDPESKFKGQ-KVWLGIFT 319
Cdd:NF033804  566 VELYGNIGDKSDWTTNVGNKTEVKWGSVLLERGQSVTATYTNLQNSYYNGKKISKIVYKYTVDPSSKFKNPgKVWLGIFT 645

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  320 DPTLGVFASAYTGQVEQNTSIFIKNEFTFYDEEGNPINFDNALLSVASLNREHNSIEMAKDYTGKFVKISGSSIGEKNGM 399
Cdd:NF033804  646 DPTLGVFASAYTGQVEKDTSIFIKNEFTFYDENGQPINFDNALLSVASLNREHNSIEMAKDYTGTFVKISGSSIGEKNGM 725

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  400 IYATDTLNFKQGEGGARWTMYKNSQSGSGWDTSDAPNSWYGAGAIKMSGSNNKVTVGATSATNVMSVSEMPKVNGKDNTE 479
Cdd:NF033804  726 IYATETLNFKKGQGGSRWTMYKNSQPGSGWDSSDAPNSWYGAGAISMSGPNNSVTVGAISATNVMPSDEMPAVPGRDNTE 805

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 577034337  480 GKKPNIWYSLNGKIRAVNVPKVTKEKPTPPVEPTSPAQPTYETEKPIEPAPVAPTYEAKPTPP 542
Cdd:NF033804  806 GKKPNIWYSLNGKIRAVNVPKITKEKPTPPVAPTAPQAPTYEVEKPLEPAPVAPTYENEPTPP 868
 
Name Accession Description Interval E-value
Streccoc_I_II NF033804
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ...
 1-542 0e+00

antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.


Pssm-ID: 468188 [Multi-domain]  Cd Length: 1552  Bit Score: 905.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337    1 AKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAAVKKANADNEADYQAKLAAYQTELARVQKAN 80
Cdd:NF033804  328 AKAAYEKAVEENTAKNTAIQAENEAIKQRNAAAKATYEAALKQYEADLAAVKKANAANEADYQAKLAAYQTELARVQKAN 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   81 AEAKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAKYQKDLAEYPSKLKAYEDEQAAIKAALAE 160
Cdd:NF033804  408 ADAKAAYEKAVEDNKAKNAALQAENEAIKQRNAAAKADYEAKLAKYQADLAKYKKDLAEYPAKLKAYEDEQAKIKAALAE 487

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  161 LEKHKNEDGNLTEPSAQSLVYDLEPNANLSLTTNGKFLKASAVDDAFSKSTSKgkYDQKILQLDDLDISNLEQVDDVASS 240
Cdd:NF033804  488 LEKKKNEDGYLSEPSAQSLVYDSEPNAQLSLTTDGKLLKASAVDEAFKKDTAQ--YGKKNLQLDNLNVTNLEQADATTSS 565

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  241 MELYGNFGTKAGWTTTVSSSGVAKWGSVLLERGQSATATYTNLQNSYYNGKKISKIVYKYTVDPESKFKGQ-KVWLGIFT 319
Cdd:NF033804  566 VELYGNIGDKSDWTTNVGNKTEVKWGSVLLERGQSVTATYTNLQNSYYNGKKISKIVYKYTVDPSSKFKNPgKVWLGIFT 645

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  320 DPTLGVFASAYTGQVEQNTSIFIKNEFTFYDEEGNPINFDNALLSVASLNREHNSIEMAKDYTGKFVKISGSSIGEKNGM 399
Cdd:NF033804  646 DPTLGVFASAYTGQVEKDTSIFIKNEFTFYDENGQPINFDNALLSVASLNREHNSIEMAKDYTGTFVKISGSSIGEKNGM 725

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  400 IYATDTLNFKQGEGGARWTMYKNSQSGSGWDTSDAPNSWYGAGAIKMSGSNNKVTVGATSATNVMSVSEMPKVNGKDNTE 479
Cdd:NF033804  726 IYATETLNFKKGQGGSRWTMYKNSQPGSGWDSSDAPNSWYGAGAISMSGPNNSVTVGAISATNVMPSDEMPAVPGRDNTE 805

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 577034337  480 GKKPNIWYSLNGKIRAVNVPKVTKEKPTPPVEPTSPAQPTYETEKPIEPAPVAPTYEAKPTPP 542
Cdd:NF033804  806 GKKPNIWYSLNGKIRAVNVPKITKEKPTPPVAPTAPQAPTYEVEKPLEPAPVAPTYENEPTPP 868
GbpC pfam08363
Glucan-binding protein C; This domain is found in the Streptococcus Glucan-binding protein C ...
 162-490 2.75e-85

Glucan-binding protein C; This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.


Pssm-ID: 400594 [Multi-domain]  Cd Length: 260  Bit Score: 264.83  E-value: 2.75e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  162 EKHKNEDGNLTEPSAQSLVYDLEPNANLSLTTNGkflkasavdDAFSKSTSKGKYDQKILQ---LDDLDIsnleqvddva 238
Cdd:pfam08363   1 EKHKNEEGYVSEALAQALVFDNEPQAQLSANTRN---------QIITKGTALLGGYSKILQstgFDVYDA---------- 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  239 ssmelygnfgtkagwtttvsssgvakwgsvlLERGQSATATYTNLQNSYYNGKKISKIVYKYTVDPESKFKGqKVWLGIF 318
Cdd:pfam08363  62 -------------------------------LKKGQPVSVTYTNLQNASYNGKKISKVEYDYTVLSSPAGTG-AVNLVLF 109

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  319 TDPTLGVFASAYTGQVEQNTSIFIKNEFTFYDEEGNPINFDNA---LLSVASLNR--EHNSIEMAKDYTGKFVKISGSSI 393
Cdd:pfam08363 110 NDPTETIFAGANTGNGDKNTDIEIRMVIKFYDEDGKEILFSKEnafVFSLSSLNHndENIHLEFVKDSTGKFVKINGSSV 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  394 G-EKNGMIYATDTLNFKQgeGGARWTMyknsqsGSGWDTSDAPNSWYGAGAIKMSGSNNKVTVGAtsatnvmsvsempkv 472
Cdd:pfam08363 190 QvHGNGKIYSTGDNDYGT--NGADLNL------PSGWDTVSAKNAYYGAGVSVTSGNRITFTFGQ--------------- 246

                         330
                  ....*....|....*...
gi 577034337  473 ngkdNTEGKKPNIWYSLN 490
Cdd:pfam08363 247 ----GDSNLPGSIWFALN 260
Agg_substance NF033875
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ...
 54-513 3.36e-20

LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.


Pssm-ID: 411439 [Multi-domain]  Cd Length: 1306  Bit Score: 94.78  E-value: 3.36e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   54 ANADNEADYQAKLAAyQTELARVQKANAEAKAAYEKAVAEN------TVANAAITAENKAIKQRNTIAKADYEAKLAQYQ 127
Cdd:NF033875  146 APAENEANKSTSIPK-EFETPDVDKAVDEAKKDPNITVVEKpaedlgNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELK 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  128 ADLAKYQKDLAEYPSKLKAyedEQAAIKAALAELEKHKNEDGNLTEPSAQSLVYDLE---PNANLSLTTNGKFLKAsavd 204
Cdd:NF033875  225 AKNEKIAKENAEIAAKNKA---EKERYEKEVAEYNKHKNENGYVNEAISKNLVFDQSvvtKDTKISSIKGGKFIKA---- 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  205 dafSKSTSKGKYDQKILQLDDLDISNLEQVDDVASSMELYGNFGTKAGWtttvsssgvakwgSVLLERGQSATATYTNLq 284
Cdd:NF033875  298 ---TDFNKVNAGDSKDIFTKLSKDMGGKATGNFQNSFVKEANLGSNGGY-------------AVLLEKNKPVTVTYTGL- 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  285 NSYYNGKKISKIVYKYTVDPESKFKGQkvWLGIFTDPTLgvfASAYTGQVEQN-TSIFIKNEFTFYDEEGNPI--NFDNA 361
Cdd:NF033875  361 NASYLGRKITKAEFVYELQSSPSQSGT--LNAVFSNDPI---ITAFVGTNNVNgKDVKTRLTIKFFDASGKEVlpDKDSP 435

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  362 L-LSVASLNREHNSI----EMAKDY--TGKFVKISGSSIGEK-NGMIYATDTLNFKQGEGGArwtmyknsqSGSGWDTSD 433
Cdd:NF033875  436 FaYALSSLNSSLTNKgghaEFVSDFgaNNAFKYINGSYVKKQaDGKFYSPEDIDYGTGPSGL---------KNSDWDAVG 506

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  434 APNSWYGAGaikmsgsnnkvtVGATSATNVMSVSEMPKVNGKDNTEGKKpnIWYSLNGKIRAVNV-PKVTKEKPTPPVEP 512
Cdd:NF033875  507 HKNAYFGSG------------VGLANTPGRISFSFGMTTKGKNVPVSSA--QWFAFSTNLNAKSIkPYQNKGNPKEPEKA 572


                  .
gi 577034337  513 T 513
Cdd:NF033875  573 T 573
PRK11281 PRK11281
mechanosensitive channel MscK;
20-179 7.11e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.14  E-value: 7.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   20 TAENKAIKQR--NTIakaDYEAKLAQYQADLAAVKK--ANADneadyqAKLAAYQTELARVQKANAEakaayekaVAENT 95
Cdd:PRK11281   55 EAEDKLVQQDleQTL---ALLDKIDRQKEETEQLKQqlAQAP------AKLRQAQAELEALKDDNDE--------ETRET 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   96 VANAAItaenkaikqrntiakADYEAKLAQYQADLAKYQKDLAEYPSKLKAY----EDEQAAIKAALAELE------KHK 165
Cdd:PRK11281  118 LSTLSL---------------RQLESRLAQTLDQLQNAQNDLAEYNSQLVSLqtqpERAQAALYANSQRLQqirnllKGG 182

                         170
                  ....*....|....
gi 577034337  166 NEDGNLTEPSAQSL 179
Cdd:PRK11281  183 KVGGKALRPSQRVL 196
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
24-173 2.28e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 2.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  24 KAIKQRNTIAKADYEAKLAQYQADLAAV-KKANADNEADYQAKLAAYQTELARVQKANaeakaayekavaentVANAAIT 102
Cdd:COG4717  348 ELQELLREAEELEEELQLEELEQEIAALlAEAGVEDEEELRAALEQAEEYQELKEELE---------------ELEEQLE 412

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 577034337 103 AENKAIKQRntIAKADYEaklaQYQADLAKYQKDLAEYPSKLKAYEDEQAAIKAALAELEkhknEDGNLTE 173
Cdd:COG4717  413 ELLGELEEL--LEALDEE----ELEEELEELEEELEELEEELEELREELAELEAELEQLE----EDGELAE 473
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 35-138 3.29e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.18  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   35 ADYEAKLAQYQADLAAVKKANADNEADYQAKLAAYQTelARVQKANAEAKAAYEKAVAENTVANAAITAENKAIKQRNTI 114
Cdd:TIGR04320 257 AALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAA--AQAALATAQKELANAQAQALQTAQNNLATAQAALANAEARL 334

                          90       100
                  ....*....|....*....|....
gi 577034337  115 AKAdyEAKLAQYQADLAKYQKDLA 138
Cdd:TIGR04320 335 AKA--KEALANLNADLAKKQAALD 356
 
Name Accession Description Interval E-value
Streccoc_I_II NF033804
antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins ...
 1-542 0e+00

antigen I/II family LPXTG-anchored adhesin; Members of the antigen I/II family are adhesins with a glucan-binding domain, two types of repetitive regions, an isopeptide bond-forming domain associated with shear resistance, and a C-terminal LPXTG motif for anchoring to the cell wall. They occur in oral Streptococci, and tend to be major cell surface adhesins. Members of this family include SspA and SspB from Streptococcus gordonii, antigen I/II from S. mutans, etc.


Pssm-ID: 468188 [Multi-domain]  Cd Length: 1552  Bit Score: 905.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337    1 AKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAAVKKANADNEADYQAKLAAYQTELARVQKAN 80
Cdd:NF033804  328 AKAAYEKAVEENTAKNTAIQAENEAIKQRNAAAKATYEAALKQYEADLAAVKKANAANEADYQAKLAAYQTELARVQKAN 407

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   81 AEAKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAKYQKDLAEYPSKLKAYEDEQAAIKAALAE 160
Cdd:NF033804  408 ADAKAAYEKAVEDNKAKNAALQAENEAIKQRNAAAKADYEAKLAKYQADLAKYKKDLAEYPAKLKAYEDEQAKIKAALAE 487

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  161 LEKHKNEDGNLTEPSAQSLVYDLEPNANLSLTTNGKFLKASAVDDAFSKSTSKgkYDQKILQLDDLDISNLEQVDDVASS 240
Cdd:NF033804  488 LEKKKNEDGYLSEPSAQSLVYDSEPNAQLSLTTDGKLLKASAVDEAFKKDTAQ--YGKKNLQLDNLNVTNLEQADATTSS 565

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  241 MELYGNFGTKAGWTTTVSSSGVAKWGSVLLERGQSATATYTNLQNSYYNGKKISKIVYKYTVDPESKFKGQ-KVWLGIFT 319
Cdd:NF033804  566 VELYGNIGDKSDWTTNVGNKTEVKWGSVLLERGQSVTATYTNLQNSYYNGKKISKIVYKYTVDPSSKFKNPgKVWLGIFT 645

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  320 DPTLGVFASAYTGQVEQNTSIFIKNEFTFYDEEGNPINFDNALLSVASLNREHNSIEMAKDYTGKFVKISGSSIGEKNGM 399
Cdd:NF033804  646 DPTLGVFASAYTGQVEKDTSIFIKNEFTFYDENGQPINFDNALLSVASLNREHNSIEMAKDYTGTFVKISGSSIGEKNGM 725

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  400 IYATDTLNFKQGEGGARWTMYKNSQSGSGWDTSDAPNSWYGAGAIKMSGSNNKVTVGATSATNVMSVSEMPKVNGKDNTE 479
Cdd:NF033804  726 IYATETLNFKKGQGGSRWTMYKNSQPGSGWDSSDAPNSWYGAGAISMSGPNNSVTVGAISATNVMPSDEMPAVPGRDNTE 805

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 577034337  480 GKKPNIWYSLNGKIRAVNVPKVTKEKPTPPVEPTSPAQPTYETEKPIEPAPVAPTYEAKPTPP 542
Cdd:NF033804  806 GKKPNIWYSLNGKIRAVNVPKITKEKPTPPVAPTAPQAPTYEVEKPLEPAPVAPTYENEPTPP 868
GbpC pfam08363
Glucan-binding protein C; This domain is found in the Streptococcus Glucan-binding protein C ...
 162-490 2.75e-85

Glucan-binding protein C; This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.


Pssm-ID: 400594 [Multi-domain]  Cd Length: 260  Bit Score: 264.83  E-value: 2.75e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  162 EKHKNEDGNLTEPSAQSLVYDLEPNANLSLTTNGkflkasavdDAFSKSTSKGKYDQKILQ---LDDLDIsnleqvddva 238
Cdd:pfam08363   1 EKHKNEEGYVSEALAQALVFDNEPQAQLSANTRN---------QIITKGTALLGGYSKILQstgFDVYDA---------- 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  239 ssmelygnfgtkagwtttvsssgvakwgsvlLERGQSATATYTNLQNSYYNGKKISKIVYKYTVDPESKFKGqKVWLGIF 318
Cdd:pfam08363  62 -------------------------------LKKGQPVSVTYTNLQNASYNGKKISKVEYDYTVLSSPAGTG-AVNLVLF 109

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  319 TDPTLGVFASAYTGQVEQNTSIFIKNEFTFYDEEGNPINFDNA---LLSVASLNR--EHNSIEMAKDYTGKFVKISGSSI 393
Cdd:pfam08363 110 NDPTETIFAGANTGNGDKNTDIEIRMVIKFYDEDGKEILFSKEnafVFSLSSLNHndENIHLEFVKDSTGKFVKINGSSV 189

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  394 G-EKNGMIYATDTLNFKQgeGGARWTMyknsqsGSGWDTSDAPNSWYGAGAIKMSGSNNKVTVGAtsatnvmsvsempkv 472
Cdd:pfam08363 190 QvHGNGKIYSTGDNDYGT--NGADLNL------PSGWDTVSAKNAYYGAGVSVTSGNRITFTFGQ--------------- 246

                         330
                  ....*....|....*...
gi 577034337  473 ngkdNTEGKKPNIWYSLN 490
Cdd:pfam08363 247 ----GDSNLPGSIWFALN 260
Agg_substance NF033875
LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, ...
 54-513 3.36e-20

LPXTG-anchored aggregation substance; Aggregation substances, as described in Enterococcus, are LPXTG-anchored large surface proteins that contribute to virulence. Several closely related paralogs may be found in a single strain.


Pssm-ID: 411439 [Multi-domain]  Cd Length: 1306  Bit Score: 94.78  E-value: 3.36e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   54 ANADNEADYQAKLAAyQTELARVQKANAEAKAAYEKAVAEN------TVANAAITAENKAIKQRNTIAKADYEAKLAQYQ 127
Cdd:NF033875  146 APAENEANKSTSIPK-EFETPDVDKAVDEAKKDPNITVVEKpaedlgNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELK 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  128 ADLAKYQKDLAEYPSKLKAyedEQAAIKAALAELEKHKNEDGNLTEPSAQSLVYDLE---PNANLSLTTNGKFLKAsavd 204
Cdd:NF033875  225 AKNEKIAKENAEIAAKNKA---EKERYEKEVAEYNKHKNENGYVNEAISKNLVFDQSvvtKDTKISSIKGGKFIKA---- 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  205 dafSKSTSKGKYDQKILQLDDLDISNLEQVDDVASSMELYGNFGTKAGWtttvsssgvakwgSVLLERGQSATATYTNLq 284
Cdd:NF033875  298 ---TDFNKVNAGDSKDIFTKLSKDMGGKATGNFQNSFVKEANLGSNGGY-------------AVLLEKNKPVTVTYTGL- 360

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  285 NSYYNGKKISKIVYKYTVDPESKFKGQkvWLGIFTDPTLgvfASAYTGQVEQN-TSIFIKNEFTFYDEEGNPI--NFDNA 361
Cdd:NF033875  361 NASYLGRKITKAEFVYELQSSPSQSGT--LNAVFSNDPI---ITAFVGTNNVNgKDVKTRLTIKFFDASGKEVlpDKDSP 435

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  362 L-LSVASLNREHNSI----EMAKDY--TGKFVKISGSSIGEK-NGMIYATDTLNFKQGEGGArwtmyknsqSGSGWDTSD 433
Cdd:NF033875  436 FaYALSSLNSSLTNKgghaEFVSDFgaNNAFKYINGSYVKKQaDGKFYSPEDIDYGTGPSGL---------KNSDWDAVG 506

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  434 APNSWYGAGaikmsgsnnkvtVGATSATNVMSVSEMPKVNGKDNTEGKKpnIWYSLNGKIRAVNV-PKVTKEKPTPPVEP 512
Cdd:NF033875  507 HKNAYFGSG------------VGLANTPGRISFSFGMTTKGKNVPVSSA--QWFAFSTNLNAKSIkPYQNKGNPKEPEKA 572


                  .
gi 577034337  513 T 513
Cdd:NF033875  573 T 573
PRK11281 PRK11281
mechanosensitive channel MscK;
20-179 7.11e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.14  E-value: 7.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   20 TAENKAIKQR--NTIakaDYEAKLAQYQADLAAVKK--ANADneadyqAKLAAYQTELARVQKANAEakaayekaVAENT 95
Cdd:PRK11281   55 EAEDKLVQQDleQTL---ALLDKIDRQKEETEQLKQqlAQAP------AKLRQAQAELEALKDDNDE--------ETRET 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   96 VANAAItaenkaikqrntiakADYEAKLAQYQADLAKYQKDLAEYPSKLKAY----EDEQAAIKAALAELE------KHK 165
Cdd:PRK11281  118 LSTLSL---------------RQLESRLAQTLDQLQNAQNDLAEYNSQLVSLqtqpERAQAALYANSQRLQqirnllKGG 182

                         170
                  ....*....|....
gi 577034337  166 NEDGNLTEPSAQSL 179
Cdd:PRK11281  183 KVGGKALRPSQRVL 196
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
24-173 2.28e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 2.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  24 KAIKQRNTIAKADYEAKLAQYQADLAAV-KKANADNEADYQAKLAAYQTELARVQKANaeakaayekavaentVANAAIT 102
Cdd:COG4717  348 ELQELLREAEELEEELQLEELEQEIAALlAEAGVEDEEELRAALEQAEEYQELKEELE---------------ELEEQLE 412

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 577034337 103 AENKAIKQRntIAKADYEaklaQYQADLAKYQKDLAEYPSKLKAYEDEQAAIKAALAELEkhknEDGNLTE 173
Cdd:COG4717  413 ELLGELEEL--LEALDEE----ELEEELEELEEELEELEEELEELREELAELEAELEQLE----EDGELAE 473
Strep_SA_rep pfam06696
Streptococcal surface antigen repeat; This family consists of a number of ~25 residue long ...
 35-59 3.15e-05

Streptococcal surface antigen repeat; This family consists of a number of ~25 residue long repeats found commonly in Streptococcal surface antigens although one copy is present in the HPSR2-heavy chain potential motor protein of Giardia lamblia. This family is often found in conjunction with pfam00746.


Pssm-ID: 336475  Cd Length: 25  Bit Score: 40.86  E-value: 3.15e-05
                          10        20
                  ....*....|....*....|....*
gi 577034337   35 ADYEAKLAQYQADLAAVKKANADNE 59
Cdd:pfam06696   1 AEYEAKLAKYEADLAAVQKANADYE 25
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
7-162 3.45e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 46.40  E-value: 3.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   7 KAVAEnTVANAAItAENKAikQRNT---IAKADYEAKLAQYQADLAAVKKANADNEADYQAKLAAYQTElARVQKAnaea 83
Cdd:COG2268  192 RKIAE-IIRDARI-AEAEA--ERETeiaIAQANREAEEAELEQEREIETARIAEAEAELAKKKAEERRE-AETARA---- 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  84 kaayekaVAENTVANAAITAEnKAIKQRNTIAKADYEAKLAQYQAD--LAKYQKDLaeypsKLKAYEDEQAAIKAALAEL 161
Cdd:COG2268  263 -------EAEAAYEIAEANAE-REVQRQLEIAEREREIELQEKEAEreEAELEADV-----RKPAEAEKQAAEAEAEAEA 329


                 .
gi 577034337 162 E 162
Cdd:COG2268  330 E 330
Strep_SA_rep pfam06696
Streptococcal surface antigen repeat; This family consists of a number of ~25 residue long ...
 117-141 1.91e-04

Streptococcal surface antigen repeat; This family consists of a number of ~25 residue long repeats found commonly in Streptococcal surface antigens although one copy is present in the HPSR2-heavy chain potential motor protein of Giardia lamblia. This family is often found in conjunction with pfam00746.


Pssm-ID: 336475  Cd Length: 25  Bit Score: 38.55  E-value: 1.91e-04
                          10        20
                  ....*....|....*....|....*
gi 577034337  117 ADYEAKLAQYQADLAKYQKDLAEYP 141
Cdd:pfam06696   1 AEYEAKLAKYEADLAAVQKANADYE 25
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 3-176 2.53e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   3 AAYEKAVAENTVANAAITAENKAIKQR---NTIAKADYEAKLAQYQADLAAVKKA--------------NADNEADyQAK 65
Cdd:COG4942   58 AALERRIAALARRIRALEQELAALEAElaeLEKEIAELRAELEAQKEELAELLRAlyrlgrqpplalllSPEDFLD-AVR 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  66 LAAYQTELARVQKANAEAKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAKYQKDLAEYPSKLK 145
Cdd:COG4942  137 RLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA 216

                        170       180       190
                 ....*....|....*....|....*....|.
gi 577034337 146 AYEDEQAAIKAALAELEKHKNEDGNLTEPSA 176
Cdd:COG4942  217 ELQQEAEELEALIARLEAEAAAAAERTPAAG 247
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 35-138 3.29e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.18  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   35 ADYEAKLAQYQADLAAVKKANADNEADYQAKLAAYQTelARVQKANAEAKAAYEKAVAENTVANAAITAENKAIKQRNTI 114
Cdd:TIGR04320 257 AALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAA--AQAALATAQKELANAQAQALQTAQNNLATAQAALANAEARL 334

                          90       100
                  ....*....|....*....|....
gi 577034337  115 AKAdyEAKLAQYQADLAKYQKDLA 138
Cdd:TIGR04320 335 AKA--KEALANLNADLAKKQAALD 356
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1-179 6.40e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 6.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   1 AKAAYEKAVAENTVANAAITAENKAIKQRNTiAKADYEAKLAQYQADLAAVKKANADNEADYQ----------AKLAAYQ 70
Cdd:COG1196  258 LEAELAELEAELEELRLELEELELELEEAQA-EEYELLAELARLEQDIARLEERRRELEERLEeleeelaeleEELEELE 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  71 TELARVQKANAEAKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQyQADLAKYQKDLAEYPSKLKAYEDE 150
Cdd:COG1196  337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA-LRAAAELAAQLEELEEAEEALLER 415

                        170       180
                 ....*....|....*....|....*....
gi 577034337 151 QAAIKAALAELEKHKNEDGNLTEPSAQSL 179
Cdd:COG1196  416 LERLEEELEELEEALAELEEEEEEEEEAL 444
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2-163 1.50e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337     2 KAAYEKAVAENTVANAAITAENKAIKQRntiaKADYEAKLAQYQADLAAVKkanaDNEADYQAKLAAYQTELARVQKANA 81
Cdd:TIGR02169  338 IEELEREIEEERKRRDKLTEEYAELKEE----LEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELD 409

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337    82 EAKAAYEKAVAENTVANAAITAENKAIKQ--------RNTIAKAdyEAKLAQYQADLAKYQKDLAEYPSKLKAYEDEQAA 153
Cdd:TIGR02169  410 RLQEELQRLSEELADLNAAIAGIEAKINEleeekedkALEIKKQ--EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSK 487

                          170
                   ....*....|
gi 577034337   154 IKAALAELEK 163
Cdd:TIGR02169  488 LQRELAEAEA 497
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 21-164 2.07e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337    21 AENKAIKQRNTIAKADYEAKLAQYQADLAAVKKA--NADNE-ADYQAKLAAYQTELARVQKANAEAKAAYEKAVAENTVA 97
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEvsELEEEiEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 577034337    98 NAAItAENKAIKQRntiakadYEAKLAQYQADLAKYQKDLAEYPSKLKAYEDEQAAIKAALAELEKH 164
Cdd:TIGR02168  322 EAQL-EELESKLDE-------LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380
AcrA COG0845
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ...
 1-77 2.39e-03

Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];


Pssm-ID: 440606 [Multi-domain]  Cd Length: 324  Bit Score: 40.31  E-value: 2.39e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 577034337   1 AKAAYEKAVAEntVANAAITAE-NKAIKQRNTIAKADYEAKLAQYQADLAAVKKAnadneadyQAKLAAYQTELARVQ 77
Cdd:COG0845   66 AQAQLAAAQAQ--LELAKAELErYKALLKKGAVSQQELDQAKAALDQAQAALAAA--------QAALEQARANLAYTT 133
Strep_SA_rep pfam06696
Streptococcal surface antigen repeat; This family consists of a number of ~25 residue long ...
 60-80 4.25e-03

Streptococcal surface antigen repeat; This family consists of a number of ~25 residue long repeats found commonly in Streptococcal surface antigens although one copy is present in the HPSR2-heavy chain potential motor protein of Giardia lamblia. This family is often found in conjunction with pfam00746.


Pssm-ID: 336475  Cd Length: 25  Bit Score: 34.70  E-value: 4.25e-03
                          10        20
                  ....*....|....*....|.
gi 577034337   60 ADYQAKLAAYQTELARVQKAN 80
Cdd:pfam06696   1 AEYEAKLAKYEADLAAVQKAN 21
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 53-159 6.30e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 38.94  E-value: 6.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   53 KANADNEADYQAKLAAYQTELARVQKANAEAKAAYEKAVAENTVANAAITAENKAIKQRNTIAKADYEAKLAQYQADLAK 132
Cdd:TIGR04320 250 PNPPNSLAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNNLATAQAALAN 329

                          90       100
                  ....*....|....*....|....*..
gi 577034337  133 YQKDLAEYPSKLKAYEDEQAAIKAALA 159
Cdd:TIGR04320 330 AEARLAKAKEALANLNADLAKKQAALD 356
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 1-167 6.97e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 39.16  E-value: 6.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   1 AKAAYEKAVAENTVANAAITAENKAIKQRNTIAKAdyEAKLAQYQADLAAvkKANADNEADYQAKLAAYQTELARVQKAN 80
Cdd:PRK05035 555 ARAKAKKAAQQAANAEAEEEVDPKKAAVAAAIARA--KAKKAAQQAASAE--PEEQVAEVDPKKAAVAAAIARAKAKKAE 630

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337  81 AEAKAAYEKAVAENTVANAAitaenkaikqrnTIAKAdyEAKLAQYQADLAKyqKDLAEYPSKlkayedeqAAIKAALAE 160
Cdd:PRK05035 631 QQANAEPEEPVDPRKAAVAA------------AIARA--KARKAAQQQANAE--PEEAEDPKK--------AAVAAAIAR 686


                 ....*..
gi 577034337 161 LEKHKNE 167
Cdd:PRK05035 687 AKAKKAA 693
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 2-139 8.35e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 38.63  E-value: 8.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577034337   2 KAAYEKAVAENTVANAAITAENKAIKQRNTIAKADyeaklAQYQADLAAVKKANADNEADYQAKLAAYQTELARvQKANA 81
Cdd:PRK09510 132 KQAEEAAAKAAAAAKAKAEAEAKRAAAAAKKAAAE-----AKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAK-KKAEA 205

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 577034337  82 EAKAAYEKAVAENTVANAAITAENKAIKqrntiAKADYEAKLAQYQADLAKYQKDLAE 139
Cdd:PRK09510 206 EAKKKAAAEAKKKAAAEAKAAAAKAAAE-----AKAAAEKAAAAKAAEKAAAAKAAAE 258
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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