|
Name |
Accession |
Description |
Interval |
E-value |
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
5-503 |
0e+00 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 970.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGNVCSFKDIKDSEKIGI 84
Cdd:NF040905 1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYPHGSYEGEILFDGEVCRFKDIRDSEALGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:NF040905 81 VIIHQELALIPYLSIAENIFLGNERAKRGVIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 165 LILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETM-VKDATVSEDRIIKGMVGR 243
Cdd:NF040905 161 LILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTIETLdCRADEVTEDRIIRGMVGR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 244 DLVNRFPKREAKIGEIYFEINDWNVFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVK 323
Cdd:NF040905 241 DLEDRYPERTPKIGEVVFEVKNWTVYHPLHPERKVVDDVSLNVRRGEIVGIAGLMGAGRTELAMSVFGRSYGRNISGTVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 324 KDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQ 403
Cdd:NF040905 321 KDGKEVDVSTVSDAIDAGLAYVTEDRKGYGLNLIDDIKRNITLANLGKVSRRGVIDENEEIKVAEEYRKKMNIKTPSVFQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 404 KTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:NF040905 401 KVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVMNEG 480
|
490 500
....*....|....*....|
gi 543000761 484 RIVGELDQKDASQESIMKCI 503
Cdd:NF040905 481 RITGELPREEASQERIMRLI 500
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
2-510 |
0e+00 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 746.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSFKDIKDSEK 81
Cdd:COG1129 1 AEPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDS--GEILLDGEPVRFRSPRDAQA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 82 IGIAIIHQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKD 161
Cdd:COG1129 79 AGIAIIHQELNLVPNLSVAENIFLGREPRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 162 VKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKdATVSEDRIIKGMV 241
Cdd:COG1129 159 ARVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPV-AELTEDELVRLMV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 242 GRDLVNRFPKREAKIGEIYFEINDWNVfdpvvdgKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGK 321
Cdd:COG1129 238 GRELEDLFPKRAAAPGEVVLEVEGLSV-------GGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGAD--PADSGE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 322 VKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSI 401
Cdd:COG1129 309 IRLDGKPVRIRSPRDAIRAGIAYVPEDRKGEGLVLDLSIRENITLASLDRLSRGGLLDRRRERALAEEYIKRLRIKTPSP 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 402 LQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:COG1129 389 EQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMR 468
|
490 500
....*....|....*....|....*....
gi 543000761 482 EGRIVGELDQKDASQESIMKCIMQSNREV 510
Cdd:COG1129 469 EGRIVGELDREEATEEAIMAAATGGAAAA 497
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-508 |
0e+00 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 662.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGNVCSFKDIKDSE 80
Cdd:PRK13549 1 MMEYLLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTYEGEIIFEGEELQASNIRDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:PRK13549 81 RAGIAIIHQELALVKELSVLENIFLGNEITPGGIMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETmVKDATVSEDRIIKGM 240
Cdd:PRK13549 161 QARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHIGT-RPAAGMTEDDIITMM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 241 VGRDLVNRFPKREAKIGEIYFEINDWNVFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHiTG 320
Cdd:PRK13549 240 VGRELTALYPREPHTIGEVILEVRNLTAWDPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRW-EG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 321 KVKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSS 400
Cdd:PRK13549 319 EIFIDGKPVKIRNPQQAIAQGIAMVPEDRKRDGIVPVMGVGKNITLAALDRFTGGSRIDDAAELKTILESIQRLKVKTAS 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 401 ILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVM 480
Cdd:PRK13549 399 PELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVM 478
|
490 500
....*....|....*....|....*...
gi 543000761 481 NEGRIVGELDQKDASQESIMKCIMQSNR 508
Cdd:PRK13549 479 HEGKLKGDLINHNLTQEQVMEAALRSEH 506
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
5-502 |
2.03e-174 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 500.69 E-value: 2.03e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSFKDIKDSEKIGI 84
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDA--GSILYLGKEVTFNGPKSSQEAGI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALIPYLSIGENIFLGNE-RAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:PRK10762 82 GIIHQELNLIPQLTIAENIFLGREfVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 164 LLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI-ETMVKDATvsEDRIIKGMVG 242
Cdd:PRK10762 162 VIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQFIaEREVADLT--EDSLIEMMVG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 243 RDLVNRFPKREAKIGEIYFEINdwNVFDPVVDgkkvikNVNLKVHRGEVVGISGLMGSGRTELAMSVFGrAYGKHiTGKV 322
Cdd:PRK10762 240 RKLEDQYPRLDKAPGEVRLKVD--NLSGPGVN------DVSFTLRKGEILGVSGLMGAGRTELMKVLYG-ALPRT-SGYV 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 323 KKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSKNQV-IDENKEIQVAEELRRKLNIKSSSI 401
Cdd:PRK10762 310 TLDGHEVVTRSPQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTALRYFSRAGGsLKHADEQQAVSDFIRLFNIKTPSM 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 402 LQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:PRK10762 390 EQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMH 469
|
490 500
....*....|....*....|.
gi 543000761 482 EGRIVGELDQKDASQESIMKC 502
Cdd:PRK10762 470 EGRISGEFTREQATQEKLMAA 490
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
5-500 |
8.55e-170 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 488.95 E-value: 8.55e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGNVCSFKDIKDSEKIGI 84
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTWDGEIYWSGSPLKASNIRDTERAGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALIPYLSIGENIFLGNERAKNG-IINWNTTHIKATEYLNRVGLKESSQTL-IKDIGVGKQQLVEIAKALAKDV 162
Cdd:TIGR02633 81 VIIHQELTLVPELSVAENIFLGNEITLPGgRMAYNAMYLRAKNLLRELQLDADNVTRpVGDYGGGQQQLVEIAKALNKQA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 163 KLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETmvKDA-TVSEDRIIKGMV 241
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVAT--KDMsTMSEDDIITMMV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 242 GRDLVNRFPKREAKIGEIYFEINDWNVFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHiTGK 321
Cdd:TIGR02633 239 GREITSLYPHEPHEIGDVILEARNLTCWDVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKF-EGN 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 322 VKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSI 401
Cdd:TIGR02633 318 VFINGKPVDIRNPAQAIRAGIAMVPEDRKRHGIVPILGVGKNITLSVLKSFCFKMRIDAAAELQIIGSAIQRLKVKTASP 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 402 LQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:TIGR02633 398 FLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIG 477
|
490
....*....|....*....
gi 543000761 482 EGRIVGELDQKDASQESIM 500
Cdd:TIGR02633 478 EGKLKGDFVNHALTQEQVL 496
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
6-504 |
2.63e-159 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 462.07 E-value: 2.63e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSFKDIKDSEKIGIA 85
Cdd:PRK11288 5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDA--GSILIDGQEMRFASTTAALAAGVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLL 165
Cdd:PRK11288 83 IIYQELHLVPEMTVAENLYLGQLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 166 ILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATVSEDRIIKGMVGRDL 245
Cdd:PRK11288 163 AFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRYVATFDDMAQVDRDQLVQAMVGREI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 246 VNRFPKREAKIGEIYFEINDwnvfdpvVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKD 325
Cdd:PRK11288 243 GDIYGYRPRPLGEVRLRLDG-------LKGPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGAT--RRTAGQVYLD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 326 GKELLLKNVRQAIENGLAYVTEDRKTAGLVLI----DNIkkNISlAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSI 401
Cdd:PRK11288 314 GKPIDIRSPRDAIRAGIMLCPEDRKAEGIIPVhsvaDNI--NIS-ARRHHLRAGCLINNRWEAENADRFIRSLNIKTPSR 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 402 LQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:PRK11288 391 EQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMR 470
|
490 500
....*....|....*....|...
gi 543000761 482 EGRIVGELDQKDASQESIMKCIM 504
Cdd:PRK11288 471 EGRIAGELAREQATERQALSLAL 493
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-499 |
3.40e-158 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 459.11 E-value: 3.40e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSE 80
Cdd:COG3845 1 MMPPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQ--PDSGEILIDGKPVRIRSPRDAI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:COG3845 79 ALGIGMVHQHFMLVPNLTVAENIVLGLEPTKGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETmVKDATVSEDRIIKGM 240
Cdd:COG3845 159 GARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGT-VDTAETSEEELAELM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 241 VGRDLVNRFPKREAKIGEIYFEINDWNVFDPvvDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITG 320
Cdd:COG3845 238 VGREVLLRVEKAPAEPGEVVLEVENLSVRDD--RGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLR--PPASG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 321 KVKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGK--LSKNQVIDENKEIQVAEELRRKLNIKS 398
Cdd:COG3845 314 SIRLDGEDITGLSPRERRRLGVAYIPEDRLGRGLVPDMSVAENLILGRYRRppFSRGGFLDRKAIRAFAEELIEEFDVRT 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 399 SSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIY 478
Cdd:COG3845 394 PGPDTPARSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIA 473
|
490 500
....*....|....*....|.
gi 543000761 479 VMNEGRIVGELDQKDASQESI 499
Cdd:COG3845 474 VMYEGRIVGEVPAAEATREEI 494
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-504 |
7.47e-147 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 430.75 E-value: 7.47e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSE 80
Cdd:PRK09700 1 MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHE--PTKGTITINNINYNKLDHKLAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPYLSIGENIFLGNERAKN----GIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:PRK09700 79 QLGIGIIYQELSVIDELTVLENLYIGRHLTKKvcgvNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 157 ALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIET-MVKDatVSEDR 235
Cdd:PRK09700 159 TLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSgMVSD--VSNDD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 236 IIKGMVGRDLVNRFPKREAKIG----EIYFEINDWNVFDpvvdgKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG 311
Cdd:PRK09700 237 IVRLMVGRELQNRFNAMKENVSnlahETVFEVRNVTSRD-----RKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 312 raYGKHITGKVKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSKNQ----VIDENKEIQVA 387
Cdd:PRK09700 312 --VDKRAGGEIRLNGKDISPRSPLDAVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKgamgLFHEVDEQRTA 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 388 EELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSEL 467
Cdd:PRK09700 390 ENQRELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSEL 469
|
490 500 510
....*....|....*....|....*....|....*...
gi 543000761 468 PEILGMCDRIYVMNEGRIVGELD-QKDASQESIMKCIM 504
Cdd:PRK09700 470 PEIITVCDRIAVFCEGRLTQILTnRDDMSEEEIMAWAL 507
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
8-501 |
1.52e-124 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 372.91 E-value: 1.52e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 8 MRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSFKDIKDSEKIGIAII 87
Cdd:PRK10982 1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDS--GSILFQGKEIDFKSSKEALENGISMV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 88 HQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLIL 167
Cdd:PRK10982 79 HQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIM 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 168 DEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETM-VKDATVseDRIIKGMVGRDLV 246
Cdd:PRK10982 159 DEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQpLAGLTM--DKIIAMMVGRSLT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 247 NRFPKREAKIGEIYFEINDWNVFDpvvdgKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDG 326
Cdd:PRK10982 237 QRFPDKENKPGEVILEVRNLTSLR-----QPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFG--IREKSAGTITLHG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 327 KELLLKNVRQAIENGLAYVTEDRKTAGLV---------LIDNIKKniSLAKLGKLSKNQVIDENKEIQVAeelrrkLNIK 397
Cdd:PRK10982 310 KKINNHNANEAINHGFALVTEERRSTGIYayldigfnsLISNIRN--YKNKVGLLDNSRMKSDTQWVIDS------MRVK 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 398 SSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRI 477
Cdd:PRK10982 382 TPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRI 461
|
490 500
....*....|....*....|....
gi 543000761 478 YVMNEGRIVGELDQKDASQESIMK 501
Cdd:PRK10982 462 LVMSNGLVAGIVDTKTTTQNEILR 485
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
5-500 |
2.78e-104 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 321.62 E-value: 2.78e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEKIGI 84
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVP--PDSGTLEIGGNPCARLTPAKAHQLGI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALIPYLSIGENIFLG---NERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKD 161
Cdd:PRK15439 89 YLVPQEPLLFPNLSVKENILFGlpkRQASMQ----------KMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 162 VKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGaTIETMVKDATVSEDRIIKGMV 241
Cdd:PRK15439 159 SRILILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDG-TIALSGKTADLSTDDIIQAIT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 242 ----GRDLVNRFPKREAKIGEIYFEINDWnvfdPVVDGKKV----IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG-R 312
Cdd:PRK15439 238 paarEKSLSASQKLWLELPGNRRQQAAGA----PVLTVEDLtgegFRNISLEVRAGEILGLAGVVGAGRTELAETLYGlR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 313 aygKHITGKVKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNIKKNISlaklgKLSKNQV---IDENKEIQVAEE 389
Cdd:PRK15439 314 ---PARGGRIMLNGKEINALSTAQRLARGLVYLPEDRQSSGLYLDAPLAWNVC-----ALTHNRRgfwIKPARENAVLER 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 390 LRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPE 469
Cdd:PRK15439 386 YRRALNIKFNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEE 465
|
490 500 510
....*....|....*....|....*....|.
gi 543000761 470 ILGMCDRIYVMNEGRIVGELDQKDASQESIM 500
Cdd:PRK15439 466 IEQMADRVLVMHQGEISGALTGAAINVDTIM 496
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
257-485 |
1.12e-75 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 236.17 E-value: 1.12e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 257 GEIYFEINDwnvfdpvVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRQ 336
Cdd:cd03215 1 GEPVLEVRG-------LSVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLR--PPASGEITLDGKPVTRRSPRD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 337 AIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLgklsknqvidenkeiqvaeelrrklniksssilqktgnLSGGNQQKV 416
Cdd:cd03215 72 AIRAGIAYVPEDRKREGLVLDLSVAENIALSSL--------------------------------------LSGGNQQKV 113
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 417 VLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:cd03215 114 VLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
6-224 |
7.15e-62 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 199.58 E-value: 7.15e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFKDIKDSEKIGIA 85
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPD--SGEILVDGKEVSFASPRDARRAGIA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQelalipyLSIGEniflgnerakngiinwntthikateylnrvglkessqtlikdigvgkQQLVEIAKALAKDVKLL 165
Cdd:cd03216 79 MVYQ-------LSVGE-----------------------------------------------RQMVEIARALARNARLL 104
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 166 ILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:cd03216 105 ILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
5-486 |
3.16e-57 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 198.59 E-value: 3.16e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPY-GSYSGDIIFEGnvcsfKDIKD-SE 80
Cdd:COG1123 4 LLEVRDLSVRYPGgdVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHgGRISGEVLLDG-----RDLLElSE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KI---GIAIIHQE--LALIPyLSIGENIFLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIA 155
Cdd:COG1123 79 ALrgrRIGMVFQDpmTQLNP-VTVGDQIAEALE---NLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 156 KALAKDVKLLILDEPTAALneeD----SDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATV 231
Cdd:COG1123 155 MALALDPDLLIADEPTTAL---DvttqAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEIL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 232 SEDRIIKGMVGRDLVNRFPKREAKIGEIYFEINDWNV--FDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsv 309
Cdd:COG1123 232 AAPQALAAVPRLGAARGRAAPAAAAAEPLLEVRNLSKryPVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLA--- 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 310 fgraygKHITGKVKKDGKELLL--KNVRQAIENGLAyvtEDRKTAGLVLID---------NIKKNIS--LAKLGKLSKNQ 376
Cdd:COG1123 309 ------RLLLGLLRPTSGSILFdgKDLTKLSRRSLR---ELRRRVQMVFQDpysslnprmTVGDIIAepLRLHGLLSRAE 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 377 VIDenkeiQVAEELRR-KLnikSSSILQKT-GNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLA 454
Cdd:COG1123 380 RRE-----RVAELLERvGL---PPDLADRYpHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQ 451
|
490 500 510
....*....|....*....|....*....|...
gi 543000761 455 EE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG1123 452 RElGLTYLFISHDLAVVRYIADRVAVMYDGRIV 484
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
6-222 |
2.13e-46 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 161.84 E-value: 2.13e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI--KDSEKI- 82
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLR--PTSGSVLFDG-----EDItgLPPHEIa 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 --GIAIIHQELALIPYLSIGENIFLG-NERAKNGIINWNTTHI------KATEYLNRVGLKESSQTLIKDIGVGKQQLVE 153
Cdd:cd03219 74 rlGIGRTFQIPRLFPELTVLENVMVAaQARTGSGLLLARARREereareRAEELLERVGLADLADRPAGELSYGQQRRLE 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 154 IAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:cd03219 154 IARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVI 222
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
5-222 |
2.44e-44 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 156.74 E-value: 2.44e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI--KDSEKI 82
Cdd:COG0411 4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYR--PTSGRILFDG-----RDItgLPPHRI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 ---GIAIIHQELALIPYLSIGENIFLG-----NERAKNGIINWNTTHI-------KATEYLNRVGLKESSQTLIKDIGVG 147
Cdd:COG0411 77 arlGIARTFQNPRLFPELTVLENVLVAaharlGRGLLAALLRLPRARReereareRAEELLERVGLADRADEPAGNLSYG 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 148 KQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLEL-ILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:COG0411 157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELiRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVI 232
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
6-233 |
2.31e-35 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 132.11 E-value: 2.31e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI-KDSEKIG- 83
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLR--PTSGEVRVLG-----EDVaRDPAEVRr 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 -IAIIHQELALIPYLSIGENI-FLGneRAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKD 161
Cdd:COG1131 74 rIGYVPQEPALYPDLTVRENLrFFA--RLYG--LPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHD 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 162 VKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGatieTMVKDATVSE 233
Cdd:COG1131 150 PELLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKG----RIVADGTPDE 217
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
6-219 |
6.13e-35 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 130.30 E-value: 6.13e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDS- 79
Cdd:cd03255 1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDR--PTSGEVRVDGtDISKLSEKELAa 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 ---EKIGIaiIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:cd03255 79 frrRHIGF--VFQSFNLLPDLTALENVELPLLLAG---VPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIAR 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 157 ALAKDVKLLILDEPTAALneeDSDNLLEL----ILELKKHGITSIIISHKlNEVMKVADSITVLRDG 219
Cdd:cd03255 154 ALANDPKIILADEPTGNL---DSETGKEVmellRELNKEAGTTIVVVTHD-PELAEYADRIIELRDG 216
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
21-172 |
4.71e-34 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 125.45 E-value: 4.71e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGNVCSFKDIKDSEKiGIAIIHQELALIPYLSIG 100
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSP--TEGTILLDGQDLTDDERKSLRK-EIGYVFQDPQLFPRLTVR 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 101 ENIFLGNErakngIINWNTTHIK--ATEYLNRVGLKESSQTLIKDIG----VGKQQLVEIAKALAKDVKLLILDEPTA 172
Cdd:pfam00005 78 ENLRLGLL-----LKGLSKREKDarAEEALEKLGLGDLADRPVGERPgtlsGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-486 |
1.20e-33 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 133.66 E-value: 1.20e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKS-TLMSVLsGIYPYGS--YSGDIIFEGnvcsf 73
Cdd:COG4172 2 MSMPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvTALSIL-RLLPDPAahPSGSILFDG----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 74 KDI-KDSEKI-----G--IAIIHQE--LALIPYLSIGENIF--------LGNERAKNGIInwntthikatEYLNRVGLKE 135
Cdd:COG4172 76 QDLlGLSERElrrirGnrIAMIFQEpmTSLNPLHTIGKQIAevlrlhrgLSGAAARARAL----------ELLERVGIPD 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 136 sSQTLIKDI-----GvGKQQLVEIAKALAKDVKLLILDEPTAALN---------------EEdsdnllelilelkkHGIT 195
Cdd:COG4172 146 -PERRLDAYphqlsG-GQRQRVMIAMALANEPDLLIADEPTTALDvtvqaqildllkdlqRE--------------LGMA 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 196 SIIISHKLNEVMKVADSITVLRDGATIET------------------------MVKDATVSEDRIIkgMVGRDLVNRFPK 251
Cdd:COG4172 210 LLLITHDLGVVRRFADRVAVMRQGEIVEQgptaelfaapqhpytrkllaaeprGDPRPVPPDAPPL--LEARDLKVWFPI 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 252 REAkigeiyfeindwnVFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVF------GRAY--GKHITGkvk 323
Cdd:COG4172 288 KRG-------------LFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLrlipseGEIRfdGQDLDG--- 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 324 KDGKELL-LK------------------NVRQAIENGLAyvtedrktaglvlIDNIkknislaklgKLSKNQvidenKEI 384
Cdd:COG4172 352 LSRRALRpLRrrmqvvfqdpfgslsprmTVGQIIAEGLR-------------VHGP----------GLSAAE-----RRA 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 385 QVAEelrrklniksssILQKTG-----------NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL 453
Cdd:COG4172 404 RVAE------------ALEEVGldpaarhryphEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDL 471
|
570 580 590
....*....|....*....|....*....|....
gi 543000761 454 -AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG4172 472 qREHGLAYLFISHDLAVVRALAHRVMVMKDGKVV 505
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
6-219 |
1.39e-33 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 125.20 E-value: 1.39e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGNVCSFKDIKDSEKIGia 85
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKP--DSGEIKVLGKDIKKEPEEVKRRIG-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLgnerakngiinwntthikateylnrvglkesSQtlikdigvGKQQLVEIAKALAKDVKLL 165
Cdd:cd03230 77 YLPEEPSLYENLTVRENLKL-------------------------------SG--------GMKQRLALAQALLHDPELL 117
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 166 ILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03230 118 ILDEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNG 171
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
6-219 |
1.50e-33 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 127.30 E-value: 1.50e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEKI-- 82
Cdd:cd03256 1 IEVENLSKTYPnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVE--PTSGSVLIDGTDINKLKGKALRQLrr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIAIIHQELALIPYLSIGENI---FLGNERAKNGIINWNTTH--IKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKA 157
Cdd:cd03256 79 QIGMIFQQFNLIERLSVLENVlsgRLGRRSTWRSLFGLFPKEekQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 158 LAKDVKLLILDEPTAALNEEDSDNLLEL-ILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03256 159 LMQQPKLILADEPVASLDPASSRQVMDLlKRINREEGITVIVSLHQVDLAREYADRIVGLKDG 221
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
5-223 |
1.51e-33 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 126.70 E-value: 1.51e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFP----GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEG-NVCSFKDIKDS 79
Cdd:COG1136 4 LLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRP--TSGEVLIDGqDISSLSERELA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 ----EKIGiaIIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIA 155
Cdd:COG1136 82 rlrrRHIG--FVFQFFNLLPELTALENVALPLLLAG---VSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIA 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 156 KALAKDVKLLILDEPTAALneeDSDNLLEL----ILELKKHGITSIIISHKLnEVMKVADSITVLRDGATIE 223
Cdd:COG1136 157 RALVNRPKLILADEPTGNL---DSKTGEEVlellRELNRELGTTIVMVTHDP-ELAARADRVIRLRDGRIVS 224
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
6-486 |
1.95e-33 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 133.00 E-value: 1.95e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDII----------------FEGN 69
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEPTSGRIIyhvalcekcgyverpsKVGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 70 VCS------------FKDIKDSEKIG----IAIIHQE-LALIPYLSIGENIF-----LGNErAKNGIInwntthiKATEY 127
Cdd:TIGR03269 81 PCPvcggtlepeevdFWNLSDKLRRRirkrIAIMLQRtFALYGDDTVLDNVLealeeIGYE-GKEAVG-------RAVDL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 128 LNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNL-LELILELKKHGITSIIISHKLNEV 206
Cdd:TIGR03269 153 IEMVQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVhNALEEAVKASGISMVLTSHWPEVI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 207 MKVADSITVLRDGATIETMVKDATVSedriiKGMVGRDLVNRFpkREAKIGEIYFEINDWNVFDPVVDgKKVIK---NVN 283
Cdd:TIGR03269 233 EDLSDKAIWLENGEIKEEGTPDEVVA-----VFMEGVSEVEKE--CEVEVGEPIIKVRNVSKRYISVD-RGVVKavdNVS 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 284 LKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVK-KDGKELLLKNVRQAIENGLA--YVTEDRKTAGL----VL 356
Cdd:TIGR03269 305 LEVKEGEIFGIVGTSGAGKTTLSKIIAGVL--EPTSGEVNvRVGDEWVDMTKPGPDGRGRAkrYIGILHQEYDLyphrTV 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 IDNIKKNISLAKLGKLSKNQVIDENKEIQVAEElrrklniKSSSILQK-TGNLSGGNQQKVVLSKWIFTDPEVLILDEPT 435
Cdd:TIGR03269 383 LDNLTEAIGLELPDELARMKAVITLKMVGFDEE-------KAEEILDKyPDELSEGERHRVALAQVLIKEPRIVILDEPT 455
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 543000761 436 RGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:TIGR03269 456 GTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIV 507
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
6-223 |
1.25e-31 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 121.89 E-value: 1.25e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEKIGIa 85
Cdd:COG4555 2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLK--PDSGSILIDGEDVRKEPREARRQIGV- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 iIHQELALIPYLSIGENI-FLGNERAKNGIINwnttHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:COG4555 79 -LPDERGLYDRLTVRENIrYFAELYGLFDEEL----KKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKV 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 165 LILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:COG4555 154 LLLDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVA 212
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
6-219 |
1.38e-31 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 121.09 E-value: 1.38e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDS--EKIG 83
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLER--PDSGEILIDG-----RDVTGVppERRN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:cd03259 74 IGMVFQDYALFPHLTVAENIAFGLKLRG---VPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPS 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 164 LLILDEPTAALNEEDSDN-LLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03259 151 LLLLDEPLSALDAKLREElREELKELQRELGITTIYVTHDQEEALALADRIAVMNEG 207
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
6-225 |
1.10e-30 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 118.73 E-value: 1.10e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGnvcsfKDIKDSEK 81
Cdd:cd03293 1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERP--TSGEVLVDG-----EPVTGPGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 82 iGIAIIHQELALIPYLSIGENIFLGNERAkngiiNWNTTHIK--ATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALA 159
Cdd:cd03293 74 -DRGYVFQQDALLPWLTVLDNVALGLELQ-----GVPKAEARerAEELLELVGLSGFENAYPHQLSGGMRQRVALARALA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 160 KDVKLLILDEPTAAL--------NEEDSDnllelilELKKHGITSIIISHKLNEVMKVADSITVL--RDGATIETM 225
Cdd:cd03293 148 VDPDVLLLDEPFSALdaltreqlQEELLD-------IWRETGKTVLLVTHDIDEAVFLADRVVVLsaRPGRIVAEV 216
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
6-219 |
2.18e-30 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 116.52 E-value: 2.18e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDSEKIGI 84
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEE--PDSGSILIDGeDLTDLEDELPPLRRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALIPYLSIGENIFLGnerakngiinwntthikateylnrvglkessqtlikdIGVGKQQLVEIAKALAKDVKL 164
Cdd:cd03229 79 GMVFQDFALFPHLTVLENIALG-------------------------------------LSGGQQQRVALARALAMDPDV 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 165 LILDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03229 122 LLLDEPTSALDPItRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
6-225 |
3.87e-30 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 116.93 E-value: 3.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVcSFKDIKDSEKIGiA 85
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIK--PDSGEITFDGKS-YQKNIEALRRIG-A 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIhQELALIPYLSIGENIFLGNE--RAKNGIINwntthikatEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:cd03268 77 LI-EAPGFYPNLTARENLRLLARllGIRKKRID---------EVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPD 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 164 LLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETM 225
Cdd:cd03268 147 LLILDEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
7-219 |
1.83e-29 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 113.11 E-value: 1.83e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfkdiKDSEKIGIAI 86
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLK--PTSGEILIDG--------KDIAKLPLEE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 87 IHQELALIPYLSIGEniflgnerakngiinwntthikateylnrvglkessqtlikdigvgkQQLVEIAKALAKDVKLLI 166
Cdd:cd00267 71 LRRRIGYVPQLSGGQ-----------------------------------------------RQRVALARALLLNPDLLL 103
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 167 LDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd00267 104 LDEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDG 156
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-224 |
1.97e-29 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 121.16 E-value: 1.97e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFP-----GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKD 75
Cdd:COG1123 256 AAEPLLEVRNLSKRYPvrgkgGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLR--PTSGSILFDG-----KD 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 76 IKDSEKIG-------IAIIHQ--ELALIPYLSIGENI---------FLGNERAKngiinwntthiKATEYLNRVGLKES- 136
Cdd:COG1123 329 LTKLSRRSlrelrrrVQMVFQdpYSSLNPRMTVGDIIaeplrlhglLSRAERRE-----------RVAELLERVGLPPDl 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 137 --------SQtlikdigvGKQQLVEIAKALAKDVKLLILDEPTAAL---------------NEEdsdnllelilelkkHG 193
Cdd:COG1123 398 adryphelSG--------GQRQRVAIARALALEPKLLILDEPTSALdvsvqaqilnllrdlQRE--------------LG 455
|
250 260 270
....*....|....*....|....*....|.
gi 543000761 194 ITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:COG1123 456 LTYLFISHDLAVVRYIADRVAVMYDGRIVED 486
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
22-486 |
5.07e-29 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 120.20 E-value: 5.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 22 DNVNLKVKSGEVHALVGENGAGKS-TLMSVL------SGIYPygsySGDIIFEGNVCSFKDIKDSEKI---GIAIIHQE- 90
Cdd:PRK15134 26 NDVSLQIEAGETLALVGESGSGKSvTALSILrllpspPVVYP----SGDIRFHGESLLHASEQTLRGVrgnKIAMIFQEp 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 91 -LALIPYLSIGENIF--------LGNERAKNGIINWntthikateyLNRVGLKESSQTLiKD----IGVGKQQLVEIAKA 157
Cdd:PRK15134 102 mVSLNPLHTLEKQLYevlslhrgMRREAARGEILNC----------LDRVGIRQAAKRL-TDyphqLSGGERQRVMIAMA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 158 LAKDVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATVSEDRi 236
Cdd:PRK15134 171 LLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPT- 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 237 ikGMVGRDLVNRFPKRE----AKIGEIYFEINDWNVFDP--------VVDGKKVIKNVNLKVHRGEVVGISGLMGSGR-- 302
Cdd:PRK15134 250 --HPYTQKLLNSEPSGDpvplPEPASPLLDVEQLQVAFPirkgilkrTVDHNVVVKNISFTLRPGETLGLVGESGSGKst 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 303 TELAMSVFGRAygkhiTGKVKKDGKELLLKNVRQAiengLAYvtedRKTAGLVLIDnikKNISLAKlgKLSKNQVIDE-- 380
Cdd:PRK15134 328 TGLALLRLINS-----QGEIWFDGQPLHNLNRRQL----LPV----RHRIQVVFQD---PNSSLNP--RLNVLQIIEEgl 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 381 ----------NKEIQVAEELrRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTII 450
Cdd:PRK15134 390 rvhqptlsaaQREQQVIAVM-EEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALL 468
|
490 500 510
....*....|....*....|....*....|....*..
gi 543000761 451 NKLAEEGK-SIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK15134 469 KSLQQKHQlAYLFISHDLHVVRALCHQVIVLRQGEVV 505
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
6-219 |
2.88e-28 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 112.33 E-value: 2.88e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypYGSYSGDIIFEGnvcsfKDIKD--SEKIG 83
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGF--ETPTSGEILLDG-----KDITNlpPHKRP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:cd03300 74 VNTVFQNYALFPHLTVFENIAFGLRLKK---LPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPK 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 164 LLILDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03300 151 VLLLDEPLGALDLKlRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKG 207
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
5-224 |
3.23e-28 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 112.21 E-value: 3.23e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSE 80
Cdd:cd03257 1 LLEVKNLSVSFPTgggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLK--PTSGSIIFDGKDLLKLSRRLRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIG--IAIIHQE--LALIPYLSIGENIflgNERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIK---DIGVGKQQLVE 153
Cdd:cd03257 79 IRRkeIQMVFQDpmSSLNPRMTIGEQI---AEPLRIHGKLSKKEARKEAVLLLLVGVGLPEEVLNRyphELSGGQRQRVA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 154 IAKALAKDVKLLILDEPTAALneeDSDNLLEL----ILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:cd03257 156 IARALALNPKLLIADEPTSAL---DVSVQAQIldllKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
7-219 |
5.65e-28 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 111.02 E-value: 5.65e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYpyGSYSGDIIFEGNVCSFKDIKD-SEKIG 83
Cdd:cd03225 1 ELKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLL--GPTSGEVLVDGKDLTKLSLKElRRKVG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 I-----------AIIHQELALIPylsigENIFLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLV 152
Cdd:cd03225 79 LvfqnpddqffgPTVEEEVAFGL-----ENLGLPEEEIEE----------RVEEALELVGLEGLRDRSPFTLSGGQKQRV 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 153 EIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03225 144 AIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDG 210
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
6-219 |
1.95e-27 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 110.12 E-value: 1.95e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSekiGIA 85
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLER--PDSGTILFGGEDATDVPVQER---NVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLG-NERAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:cd03296 78 FVFQHYALFRHMTVFDNVAFGlRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKV 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 165 LILDEPTAALN-----------EEDSDNLlelilelkkhGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03296 158 LLLDEPFGALDakvrkelrrwlRRLHDEL----------HVTTVFVTHDQEEALEVADRVVVMNKG 213
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
274-486 |
2.95e-27 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 109.34 E-value: 2.95e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHI-------TGKVKKDGKELLLKNVRQAienglayvt 346
Cdd:COG1122 12 GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLL---------RLLngllkptSGEVLVDGKDITKKNLREL--------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 347 edRKTAGLV-------LI-DNIKKNI--SLAKLGkLSKNQVIDenkeiQVAEELRRkLNIksSSILQK-TGNLSGGNQQK 415
Cdd:COG1122 74 --RRKVGLVfqnpddqLFaPTVEEDVafGPENLG-LPREEIRE-----RVEEALEL-VGL--EHLADRpPHELSGGQKQR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 416 V----VLSkwifTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG1122 143 VaiagVLA----MEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIV 213
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
7-219 |
3.91e-27 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 110.04 E-value: 3.91e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPGVKaldNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG---NVCSFKDIKDSEKIG 83
Cdd:cd03294 29 EILKKTGQTVGVN---DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIE--PTSGKVLIDGqdiAAMSRKELRELRRKK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:cd03294 104 ISMVFQSFALLPHRTVLENVAFGLEVQG---VPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPD 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 164 LLILDEPTAALneeD----SDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03294 181 ILLMDEAFSAL---DplirREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDG 237
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
6-219 |
6.41e-27 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 108.29 E-value: 6.41e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI--KDSEKI- 82
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLP--PRSGSIRFDG-----RDItgLPPHERa 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 --GIAIIHQELALIPYLSIGENIFLGNERAKNGIINWNtthikateyLNRV-----GLKESSQTLIKDIGVGKQQLVEIA 155
Cdd:cd03224 74 raGIGYVPEGRRIFPELTVEENLLLGAYARRRAKRKAR---------LERVyelfpRLKERRKQLAGTLSGGEQQMLAIA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 156 KALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03224 145 RALMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERG 208
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
6-219 |
6.73e-27 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 106.70 E-value: 6.73e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGNVCSFKDIKDSEKIg 83
Cdd:cd03228 1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDP--TSGEILIDGVDLRDLDLESLRKN- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQElaliPYL---SIGENIFLGNERakngiinwntthikateylnrvglkessqtlikdigvgkqQLVEIAKALAK 160
Cdd:cd03228 78 IAYVPQD----PFLfsgTIRENILSGGQR----------------------------------------QRIAIARALLR 113
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 161 DVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDG 219
Cdd:cd03228 114 DPPILILDEATSALDPE-TEALILEALRALAKGKTVIVIAHRLSTIRD-ADRIIVLDDG 170
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
6-223 |
9.02e-27 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 114.55 E-value: 9.02e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDsekIG 83
Cdd:COG2274 474 IELENVSFRYPGdsPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYE--PTSGRILIDG-----IDLRQ---ID 543
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIP---YL---SIGENIFLGNERAKNGIINWNTTHIKATEYLNRvgLKESSQTLIKDIGV----GKQQLVE 153
Cdd:COG2274 544 PASLRRQIGVVLqdvFLfsgTIRENITLGDPDATDEEIIEAARLAGLHDFIEA--LPMGYDTVVGEGGSnlsgGQRQRLA 621
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 154 IAKALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLnEVMKVADSITVLRDGATIE 223
Cdd:COG2274 622 IARALLRNPRILILDEATSALDAE-TEAIILENLRRLLKGRTVIIIAHRL-STIRLADRIIVLDKGRIVE 689
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
6-219 |
9.63e-27 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 107.62 E-value: 9.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGnVCSFKDIKDSEKI--G 83
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDS--GTIIIDG-LKLTDDKKNINELrqK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIFLGNERAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:cd03262 78 VGMVFQQFNLFPHLTVLENITLAPIKVKG--MSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPK 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 164 LLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03262 156 VMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDG 211
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-174 |
1.28e-26 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 108.64 E-value: 1.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFP----GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI 76
Cdd:COG1116 3 AAAPALELRGVSKRFPtgggGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEK--PTSGEVLVDG-----KPV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 77 KDSEKiGIAIIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDI-GvGKQQLVEIA 155
Cdd:COG1116 76 TGPGP-DRGVVFQEPALLPWLTVLDNVALGLELRG---VPKAERRERARELLELVGLAGFEDAYPHQLsG-GMRQRVAIA 150
|
170
....*....|....*....
gi 543000761 156 KALAKDVKLLILDEPTAAL 174
Cdd:COG1116 151 RALANDPEVLLMDEPFGAL 169
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
275-485 |
1.84e-26 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 105.56 E-value: 1.84e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLknvrqaieNGLAYVTEDRKtagl 354
Cdd:cd03230 12 KKTALDDISLTVEKGEIYGLLGPNGAGKTTLI---------KIILGLLKPDSGEIKV--------LGKDIKKEPEE---- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 vlidnIKKNISLaklgklsknqVIDEN---KEIQVAEELRrklniksssilqktgnLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:cd03230 71 -----VKRRIGY----------LPEEPslyENLTVRENLK----------------LSGGMKQRLALAQALLHDPELLIL 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:cd03230 120 DEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
277-486 |
1.87e-26 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 107.21 E-value: 1.87e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKEL--LLKNVRQAIENGLAYVTED------ 348
Cdd:cd03257 19 KALDDVSFSIKKGETLGLVGESGSGKSTLARAILG--LLKPTSGSIIFDGKDLlkLSRRLRKIRRKEIQMVFQDpmssln 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 -RKTAGLVLIDnikkniSLAKLGKLSKnqviDENKEIQVAEELRRKLNikSSSILQK-TGNLSGGNQQKVVLSKWIFTDP 426
Cdd:cd03257 97 pRMTIGEQIAE------PLRIHGKLSK----KEARKEAVLLLLVGVGL--PEEVLNRyPHELSGGQRQRVAIARALALNP 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03257 165 KLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAGKIV 225
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
16-224 |
1.95e-26 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 106.93 E-value: 1.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNvcsfkDIKDSEKI----GIAIIHQEl 91
Cdd:cd03254 14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYD--PQKGQILIDGI-----DIRDISRKslrsMIGVVLQD- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 92 aliPYL---SIGENIFLGNERAKNGIINWNTTHIKATEYLNRvgLKESSQTLIKDIG----VGKQQLVEIAKALAKDVKL 164
Cdd:cd03254 86 ---TFLfsgTIMENIRLGRPNATDEEVIEAAKEAGAHDFIMK--LPNGYDTVLGENGgnlsQGERQLLAIARAMLRDPKI 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 165 LILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVmKVADSITVLRDGATIET 224
Cdd:cd03254 161 LILDEATSNIDTE-TEKLIQEALEKLMKGRTSIIIAHRLSTI-KNADKILVLDDGKIIEE 218
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
6-233 |
2.26e-26 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 107.03 E-value: 2.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKD-SEKIG 83
Cdd:COG1122 1 IELENLSFSYPgGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLK--PTSGEVLVDGKDITKKNLRElRRKVG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 I-----------AIIHQELALIPylsigENIFLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLV 152
Cdd:COG1122 79 LvfqnpddqlfaPTVEEDVAFGP-----ENLGLPREEIRE----------RVEEALELVGLEHLADRPPHELSGGQKQRV 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 153 EIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGatieTMVKDATVS 232
Cdd:COG1122 144 AIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDG----RIVADGTPR 219
|
.
gi 543000761 233 E 233
Cdd:COG1122 220 E 220
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
276-484 |
4.84e-26 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 105.63 E-value: 4.84e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNVRQAienglayvtedRKTAGLV 355
Cdd:cd03225 14 RPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNG--LLGPTSGEVLVDGKDLTKLSLKEL-----------RRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LID--------NIKKNISLAKlgklsKNQVIDENKEIQVAEELRRKLNIKSssiLQK--TGNLSGGNQQKVVLSKWIFTD 425
Cdd:cd03225 81 FQNpddqffgpTVEEEVAFGL-----ENLGLPEEEIEERVEEALELVGLEG---LRDrsPFTLSGGQKQRVAIAGVLAMD 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:cd03225 153 PDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
274-501 |
4.96e-26 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 106.05 E-value: 4.96e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLL--KNVRQAIENGLayvTEDRKT 351
Cdd:cd03261 11 GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLL---------RLIVGLLRPDSGEVLIdgEDISGLSEAEL---YRLRRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 AGLV-----LID--NIKKNIS--LAKLGKLSKNQvIDEnkeiQVAEELRRkLNIKSSsILQKTGNLSGGNQQKVVLSKWI 422
Cdd:cd03261 79 MGMLfqsgaLFDslTVFENVAfpLREHTRLSEEE-IRE----IVLEKLEA-VGLRGA-EDLYPAELSGGMKKRVALARAL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV--GELDQKDASQESI 499
Cdd:cd03261 152 ALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVaeGTPEELRASDDPL 231
|
..
gi 543000761 500 MK 501
Cdd:cd03261 232 VR 233
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
274-503 |
5.81e-26 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 106.10 E-value: 5.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKELllKNVRQAIENGLAYVTEDRktaG 353
Cdd:COG4555 12 GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDS--GSILIDGEDV--RKEPREARRQIGVLPDER---G 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLakLGKLSKNQVIDENKEIqvaEELRRKLNIksSSIL-QKTGNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:COG4555 85 LYDRLTVRENIRY--FAELYGLFDEELKKRI---EELIELLGL--EEFLdRRVGELSTGMKKKVALARALVHDPKVLLLD 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKDASQESIMKCI 503
Cdd:COG4555 158 EPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENL 228
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
274-486 |
7.39e-26 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 105.53 E-value: 7.39e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMsvfgraygKHITGKVKKDGKELLL---------KNVRQAIenglAY 344
Cdd:COG1131 11 GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTT-I--------RMLLGLLRPTSGEVRVlgedvardpAEVRRRI----GY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 345 VTEDrktagLVLIDN--IKKNISL-AKLGKLSKNQVIdenkeiQVAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKW 421
Cdd:COG1131 78 VPQE-----PALYPDltVRENLRFfARLYGLPRKEAR------ERIDELLELFGL-TDAADRKVGTLSGGMKQRLGLALA 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG1131 146 LLHDPELLILDEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIV 210
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
6-224 |
8.48e-26 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 111.00 E-value: 8.48e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDsekIGI 84
Cdd:COG4988 337 IELEDVSFSYPgGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLP--PYSGSILING-----VDLSD---LDP 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALI---PYL---SIGENIFLGNERAkngiinwNTTHIKATeyLNRVGLKE--SS-----QTLIKDIGVG---- 147
Cdd:COG4988 407 ASWRRQIAWVpqnPYLfagTIRENLRLGRPDA-------SDEELEAA--LEAAGLDEfvAAlpdglDTPLGEGGRGlsgg 477
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 148 -KQQLVeIAKALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLnEVMKVADSITVLRDGATIET 224
Cdd:COG4988 478 qAQRLA-LARALLRDAPLLLLDEPTAHLDAE-TEAEILQALRRLAKGRTVILITHRL-ALLAQADRILVLDDGRIVEQ 552
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
5-224 |
8.93e-26 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 105.36 E-value: 8.93e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPygsYSGDIIFEGnvcsfKDIKDS 79
Cdd:cd03258 1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLeRP---TSGSVLVDG-----TDLTLL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIG-------IAIIHQELALIPYLSIGENIFLGNErakngIINWNTTHI--KATEYLNRVGLKESSQTLIKDIGVGKQQ 150
Cdd:cd03258 73 SGKElrkarrrIGMIFQHFNLLSSRTVFENVALPLE-----IAGVPKAEIeeRVLELLELVGLEDKADAYPAQLSGGQKQ 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 151 LVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:cd03258 148 RVGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEE 222
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
5-219 |
9.67e-26 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 105.90 E-value: 9.67e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGnvcsfKDIKD--SEKI 82
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKP--SSGEVLLDG-----RDLASlsRREL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 G--IAIIHQELALIPYLSIGENIFLGneRA--KNGIINWNTT-HIKATEYLNRVGLKESSQTLIKDI-GvGKQQLVEIAK 156
Cdd:COG1120 74 ArrIAYVPQEPPAPFGLTVRELVALG--RYphLGLFGRPSAEdREAVEEALERTGLEHLADRPVDELsG-GERQRVLIAR 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 157 ALAKDVKLLILDEPTAAL---------------NEEdsdnllelilelkkHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:COG1120 151 ALAQEPPLLLLDEPTSHLdlahqlevlellrrlARE--------------RGRTVVMVLHDLNLAARYADRLVLLKDG 214
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
6-222 |
1.17e-25 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 104.28 E-value: 1.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVcsfKDIKDSEKIGIa 85
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIIL--PDSGEVLFDGKP---LDIAARNRIGY- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 iIHQELALIPYLSIGEN-IFLGNERA--KNGIINWntthikATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDV 162
Cdd:cd03269 75 -LPEERGLYPKMKVIDQlVYLAQLKGlkKEEARRR------IDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDP 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 163 KLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:cd03269 148 ELLILDEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
278-486 |
1.75e-25 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 104.05 E-value: 1.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG--RAYGkhitGKVKKDGKELLLKNVRQAIENGLAYVTEDRKT-AGL 354
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGllPPRS----GSIRFDGRDITGLPPHERARAGIGYVPEGRRIfPEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKknISLAKLGKLSKNQVIDEnkeiqVAE---ELRRKLNiksssilQKTGNLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:cd03224 91 TVEENLL--LGAYARRRAKRKARLER-----VYElfpRLKERRK-------QLAGTLSGGEQQMLAIARALMSRPKLLLL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03224 157 DEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVV 211
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1-244 |
2.20e-25 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 104.69 E-value: 2.20e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-PYGsysGDIIFEGnvcsfKDIK-- 77
Cdd:PRK11300 1 MSQPLLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYkPTG---GTILLRG-----QHIEgl 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 78 DSEKI---GIAIIHQELALIPYLSIGENIFLGNER-AKNGIIN--WNTTHIK---------ATEYLNRVGLKESSQTLIK 142
Cdd:PRK11300 73 PGHQIarmGVVRTFQHVRLFREMTVIENLLVAQHQqLKTGLFSglLKTPAFRraesealdrAATWLERVGLLEHANRQAG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 143 DIGVGKQQLVEIAKALAKDVKLLILDEPTAALN-EEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGAT 221
Cdd:PRK11300 153 NLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNpKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTP 232
|
250 260
....*....|....*....|...
gi 543000761 222 IETMVKDATVSEDRIIKGMVGRD 244
Cdd:PRK11300 233 LANGTPEEIRNNPDVIKAYLGEA 255
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
5-219 |
3.66e-25 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 106.84 E-value: 3.66e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSE--KI 82
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQ--PTAGQIMLDG-----VDLSHVPpyQR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIAIIHQELALIPYLSIGENIFLG--NERAKNGIINwntthIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:PRK11607 92 PINMMFQSYALFPHMTVEQNIAFGlkQDKLPKAEIA-----SRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAK 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK11607 167 RPKLLLLDEPMGALDKKLRDRMQLEVVDILERvGVTCVMVTHDQEEAMTMAGRIAIMNRG 226
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
19-222 |
3.82e-25 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 103.14 E-value: 3.82e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVK---SGEVHALVGENGAGKSTLMSVLSGI-YPYGsysGDIIFEGnVCSFkdikDSEKI--------GIAI 86
Cdd:cd03297 8 KRLPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLeKPDG---GTIVLNG-TVLF----DSRKKinlppqqrKIGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 87 IHQELALIPYLSIGENIFLGNERAKNGIINwntthIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:cd03297 80 VFQQYALFPHLNVRENLAFGLKRKRNREDR-----ISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 167 LDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:cd03297 155 LDEPFSALDRALRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
274-481 |
1.20e-24 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 101.46 E-value: 1.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRqaiengLAYVTE----DR 349
Cdd:cd03235 10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLL--KPTSGSIRVFGKPLEKERKR------IGYVPQrrsiDR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 ----KTAGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLniksssilqktGNLSGGNQQKVVLSKWIFTD 425
Cdd:cd03235 82 dfpiSVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQI-----------GELSGGQQQRVLLARALVQD 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:cd03235 151 PDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLN 206
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
5-216 |
1.44e-24 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 103.98 E-value: 1.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-PYGSYSGDIIFEGnvcsfKDI--- 76
Cdd:COG0444 1 LLEVRNLKVYFPTrrgvVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLpPPGITSGEILFDG-----EDLlkl 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 77 --KDSEKI---GIAIIHQE--LALIPYLSIGENI--------FLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLi 141
Cdd:COG0444 76 seKELRKIrgrEIQMIFQDpmTSLNPVMTVGDQIaeplrihgGLSKAEARE----------RAIELLERVGLPDPERRL- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 142 kdigvgKQ----------QLVEIAKALAKDVKLLILDEPTAAL---------------NEEdsdnllelilelkkHGITS 196
Cdd:COG0444 145 ------DRyphelsggmrQRVMIARALALEPKLLIADEPTTALdvtiqaqilnllkdlQRE--------------LGLAI 204
|
250 260
....*....|....*....|
gi 543000761 197 IIISHKLNEVMKVADSITVL 216
Cdd:COG0444 205 LFITHDLGVVAEIADRVAVM 224
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
6-219 |
2.82e-24 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 101.04 E-value: 2.82e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDSE-KIG 83
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLR--PDSGEVLIDGeDISGLSEAELYRlRRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENI-FLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDV 162
Cdd:cd03261 79 MGMLFQSGALFDSLTVFENVaFPLRE---HTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 163 KLLILDEPTAALNEEDSDNLLE-LILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03261 156 ELLLYDEPTAGLDPIASGVIDDlIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDG 213
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
5-210 |
3.65e-24 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 100.94 E-value: 3.65e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLM---SVLSGIYpygsySGDIIFEGnvcsfKDIKDSeK 81
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLrciNKLEEIT-----SGDLIVDG-----LKVNDP-K 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 82 IGIAIIHQE-------LALIPYLSIGENIFLGNERAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEI 154
Cdd:PRK09493 70 VDERLIRQEagmvfqqFYLFPHLTALENVMFGPLRVRG--ASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAI 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 155 AKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVA 210
Cdd:PRK09493 148 ARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVA 203
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
5-180 |
3.99e-24 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 100.51 E-value: 3.99e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVcsfKDIKDSE-- 80
Cdd:COG2884 1 MIRFENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEER--PTSGQVLVNGqDL---SRLKRREip 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 ----KIGiaIIHQELALIPYLSIGENIFLGNErakngIINWNTTHIK--ATEYLNRVGLKESSQTLIKDIGVGKQQLVEI 154
Cdd:COG2884 76 ylrrRIG--VVFQDFRLLPDRTVYENVALPLR-----VTGKSRKEIRrrVREVLDLVGLSDKAKALPHELSGGEQQRVAI 148
|
170 180
....*....|....*....|....*.
gi 543000761 155 AKALAKDVKLLILDEPTAALNEEDSD 180
Cdd:COG2884 149 ARALVNRPELLLADEPTGNLDPETSW 174
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
6-219 |
4.42e-24 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 100.02 E-value: 4.42e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFKDIKDSekiGIA 85
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPT--SGRIYIGGRDVTDLPPKDR---DIA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLGNERAK------NGIINWNTTHIKATEYLNRvglkessqtLIKDIGVGKQQLVEIAKALA 159
Cdd:cd03301 76 MVFQNYALYPHMTVYDNIAFGLKLRKvpkdeiDERVREVAELLQIEHLLDR---------KPKQLSGGQRQRVALGRAIV 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 160 KDVKLLILDEP----TAALNEEdsdNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03301 147 REPKVFLMDEPlsnlDAKLRVQ---MRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDG 207
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
6-219 |
6.51e-24 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 99.40 E-value: 6.51e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPYgsySGDIIFEG-NVCSFKDIKDS--- 79
Cdd:cd03292 1 IEFINVTKTYPnGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEeLPT---SGTIRVNGqDVSDLRGRAIPylr 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGIaiIHQELALIPYLSIGENIFLGNERAKNGIINWNTthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALA 159
Cdd:cd03292 78 RKIGV--VFQDFRLLPDRNVYENVAFALEVTGVPPREIRK---RVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 160 KDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03292 153 NSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERG 212
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
6-219 |
1.01e-23 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 99.68 E-value: 1.01e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGV-KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG-IYPygsYSGDIIFEG-NVCSFKDIKDSEKI 82
Cdd:cd03295 1 IEFENVTKRYGGGkKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRlIEP---TSGEIFIDGeDIREQDPVELRRKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIAIihQELALIPYLSIGENIFLGNErakngIINWNTTHIK--ATEYLNRVGLKESS--QTLIKDIGVGKQQLVEIAKAL 158
Cdd:cd03295 78 GYVI--QQIGLFPHMTVEENIALVPK-----LLKWPKEKIRerADELLALVGLDPAEfaDRYPHELSGGQQQRVGVARAL 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 159 AKDVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03295 151 AADPPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNG 212
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
6-223 |
1.17e-23 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 104.48 E-value: 1.17e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITklF---PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGnvcsfKDIKDsekI 82
Cdd:COG1132 340 IEFENVS--FsypGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDP--TSGRILIDG-----VDIRD---L 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 G-------IAIIHQElaliPYL---SIGENIFLGNERAkngiinwntTHIKATEYLNRVGLKE--SS-----QTLIKDIG 145
Cdd:COG1132 408 TleslrrqIGVVPQD----TFLfsgTIRENIRYGRPDA---------TDEEVEEAAKAAQAHEfiEAlpdgyDTVVGERG 474
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 146 V----GKQQLVEIAKALAKDVKLLILDEPTAALneeDSDNLLELIL--ELKKHGITSIIISHKLNEVMKvADSITVLRDG 219
Cdd:COG1132 475 VnlsgGQRQRIAIARALLKDPPILILDEATSAL---DTETEALIQEalERLMKGRTTIVIAHRLSTIRN-ADRILVLDDG 550
|
....
gi 543000761 220 ATIE 223
Cdd:COG1132 551 RIVE 554
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
7-216 |
2.15e-23 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 97.99 E-value: 2.15e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsFKDIKDSEKIG--- 83
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLK--PTSGSIRVFG----KPLEKERKRIGyvp 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 -IAIIHQELaliPyLSIGENIFLGNERAKNGIINWNTTHI-KATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKD 161
Cdd:cd03235 75 qRRSIDRDF---P-ISVRDVVLMGLYGHKGLFRRLSKADKaKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQD 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 162 VKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVL 216
Cdd:cd03235 151 PDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLL 205
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-219 |
2.48e-23 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 98.51 E-value: 2.48e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDS 79
Cdd:COG1127 1 MSEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLR--PDSGEILVDGqDITGLSEKELY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 E---KIGIAIihQELALIPYLSIGENIFLGNERAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:COG1127 79 ElrrRIGMLF--QGGALFDSLTVFENVAFPLREHTD--LSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALAR 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 157 ALAKDVKLLILDEPTA---------------ALNEEdsdnllelilelkkHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:COG1127 155 ALALDPEILLYDEPTAgldpitsavidelirELRDE--------------LGLTSVVVTHDLDSAFAIADRVAVLADG 218
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
7-219 |
2.77e-23 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 96.74 E-value: 2.77e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSEKIGIAi 86
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLK--PSSGEILLDG-----KDLASLSPKELA- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 87 ihQELALIPylsigeniflgnerakngiinwntthikatEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:cd03214 73 --RKIAYVP------------------------------QALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILL 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 167 LDEPTAALneeDSDNLLE----LILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03214 121 LDEPTSHL---DIAHQIEllelLRRLARERGKTVVMVLHDLNLAARYADRVILLKDG 174
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
16-224 |
2.79e-23 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 98.38 E-value: 2.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypYGSYSGDIIFEGnvcsfKDIKD------SEKIGiaIIHQ 89
Cdd:cd03249 14 PDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERF--YDPTSGEILLDG-----VDIRDlnlrwlRSQIG--LVSQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 90 ELALIpYLSIGENIFLGNERAKngiinwNTTHIKATEYLNR----VGLKESSQTLIKDIGV----GKQQLVEIAKALAKD 161
Cdd:cd03249 85 EPVLF-DGTIAENIRYGKPDAT------DEEVEEAAKKANIhdfiMSLPDGYDTLVGERGSqlsgGQKQRIAIARALLRN 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 162 VKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIET 224
Cdd:cd03249 158 PKILLLDEATSALDAE-SEKLVQEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQ 218
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
278-488 |
3.12e-23 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 98.13 E-value: 3.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNVRQAIENGLAYVTEDRKT-AGLVL 356
Cdd:COG0410 18 VLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISG--LLPPRSGSIRFDGEDITGLPPHRIARLGIGYVPEGRRIfPSLTV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 IDNIKknislakLG--KLSKNQVIDENKEiQVAE---ELRRKLNiksssilQKTGNLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:COG0410 96 EENLL-------LGayARRDRAEVRADLE-RVYElfpRLKERRR-------QRAGTLSGGEQQMLAIGRALMSRPKLLLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 432 DEPTRG-----IDvgakyEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:COG0410 161 DEPSLGlapliVE-----EIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLE 217
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
6-223 |
4.99e-23 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 97.69 E-value: 4.99e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNvcsfkDIKD----S 79
Cdd:cd03251 1 VEFKNVTFRYPGdgPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVD--SGRILIDGH-----DVRDytlaS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGIAIIHQELALIpYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRvgLKESSQTLIKDIGV----GKQQLVEIA 155
Cdd:cd03251 74 LRRQIGLVSQDVFLF-NDTVAENIAYGRPGATREEVEEAARAANAHEFIME--LPEGYDTVIGERGVklsgGQRQRIAIA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 156 KALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:cd03251 151 RALLKDPPILILDEATSALDTE-SERLVQAALERLMKNRTTFVIAHRLSTIEN-ADRIVVLEDGKIVE 216
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
274-486 |
6.60e-23 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 96.56 E-value: 6.60e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNVRQAIenglAYVTED----- 348
Cdd:cd03226 11 KGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAG--LIKESSGSILLNGKPIKAKERRKSI----GYVMQDvdyql 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 -RKTAGLVLIDNIKknislaklgklsknqviDENKEIQVAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTDPE 427
Cdd:cd03226 85 fTDSVREELLLGLK-----------------ELDAGNEQAETVLKDLDL-YALKERHPLSLSGGQKQRLAIAAALLSGKD 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 428 VLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03226 147 LLIFDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
6-223 |
9.20e-23 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 96.48 E-value: 9.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG---IYPYGSYSGDIIFEG-NVCSFKDIKDSEK 81
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndLIPGAPDEGEVLLDGkDIYDLDVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 82 IGIAIIHQELALIPyLSIGENIFLGneRAKNGIinWNTTHIKATEY--LNRVGLKE--SSQTLIKDIGVGKQQLVEIAKA 157
Cdd:cd03260 81 RRVGMVFQKPNPFP-GSIYDNVAYG--LRLHGI--KLKEELDERVEeaLRKAALWDevKDRLHALGLSGGQQQRLCLARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 158 LAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:cd03260 156 LANEPEVLLLDEPTSALDPI-STAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVE 220
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-229 |
1.38e-22 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 96.70 E-value: 1.38e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGnvcsfKDIKDSE 80
Cdd:COG1121 2 MMMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPP--TSGTVRLFG-----KPPRRAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KiGIAIIHQELAL---IPyLSIGENIFLGNeRAKNGIINWNTT--HIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIA 155
Cdd:COG1121 75 R-RIGYVPQRAEVdwdFP-ITVRDVVLMGR-YGRRGLFRRPSRadREAVDEALERVGLEDLADRPIGELSGGQQQRVLLA 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 156 KALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSI-----TVLRDGATIETMVKDA 229
Cdd:COG1121 152 RALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVlllnrGLVAHGPPEEVLTPEN 230
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
6-174 |
1.84e-22 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 95.24 E-value: 1.84e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNvcSFKDIKDSEKIGIA 85
Cdd:COG4133 3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLP--PSAGEVLWNGE--PIRDAREDYRRRLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENI-FLGneRAKNGiinwNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:COG4133 79 YLGHADGLKPELTVRENLrFWA--ALYGL----RADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPL 152
|
170
....*....|
gi 543000761 165 LILDEPTAAL 174
Cdd:COG4133 153 WLLDEPFTAL 162
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
8-435 |
2.09e-22 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 100.14 E-value: 2.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 8 MRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEgnvcsfKDIKdsekigIAII 87
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEP--DSGEVSIP------KGLR------IGYL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 88 HQELALIPYLSIGENIFLGNER---------------------------------AKNGiinWNTTHiKATEYLNRVGLK 134
Cdd:COG0488 67 PQEPPLDDDLTVLDTVLDGDAElraleaeleeleaklaepdedlerlaelqeefeALGG---WEAEA-RAEEILSGLGFP 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 135 ESSQTliKDIGV--GKQQL-VEIAKALAKDVKLLILDEPTaalNEEDSDnllelilelkkhGI------------TSIII 199
Cdd:COG0488 143 EEDLD--RPVSElsGGWRRrVALARALLSEPDLLLLDEPT---NHLDLE------------SIewleeflknypgTVLVV 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 200 SHK---LNEvmkVADSITVLRDG----------------ATIETMVKDATVSEDRIIKGMvgRDLVNRF----------- 249
Cdd:COG0488 206 SHDryfLDR---VATRILELDRGkltlypgnysayleqrAERLEQEAAAYAKQQKKIAKE--EEFIRRFrakarkakqaq 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 250 --------------PKREAKIgEIYFEINDwNVFDPVV---------DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELA 306
Cdd:COG0488 281 srikaleklereepPRRDKTV-EIRFPPPE-RLGKKVLeleglsksyGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLL 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 307 msvfgraygKHITGKVKKDGKELLL-KNVRqaiengLAYVTEDRKT--AGLVLIDNIKknislaklgklsknQVIDENKE 383
Cdd:COG0488 359 ---------KLLAGELEPDSGTVKLgETVK------IGYFDQHQEEldPDKTVLDELR--------------DGAPGGTE 409
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 543000761 384 IQVAEELRRkLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPT 435
Cdd:COG0488 410 QEVRGYLGR-FLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPT 460
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
276-486 |
3.86e-22 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 94.27 E-value: 3.86e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKN--VRQAIENGLAYVTEDRktaG 353
Cdd:cd03269 13 VTALDDISFSVEKGEIFGLLGPNGAGKTTTI---------RMILGIILPDSGEVLFDGkpLDIAARNRIGYLPEER---G 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKN-ISLAKLGKLSKNQVIDEnkeiqvAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:cd03269 81 LYPKMKVIDQlVYLAQLKGLKKEEARRR------IDEWLERLEL-SEYANKRVEELSKGNQQKVQFIAAVIHDPELLILD 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03269 154 EPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-219 |
6.79e-22 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 97.07 E-value: 6.79e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEfiLEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGnvcsfKDIKD-- 78
Cdd:COG3839 1 MAS--LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPT--SGEILIGG-----RDVTDlp 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SEKIGIAIIHQELALIPYLSIGENIFLG-----------NERAKN-----GIinwntthikaTEYLNRvglkessqtLIK 142
Cdd:COG3839 72 PKDRNIAMVFQSYALYPHMTVYENIAFPlklrkvpkaeiDRRVREaaellGL----------EDLLDR---------KPK 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 143 DIGVGKQQLVEIAKALAKDVKLLILDEPT---------------AALNEEdsdnllelilelkkHGITSIIISHKLNEVM 207
Cdd:COG3839 133 QLSGGQRQRVALGRALVREPKVFLLDEPLsnldaklrvemraeiKRLHRR--------------LGTTTIYVTHDQVEAM 198
|
250
....*....|..
gi 543000761 208 KVADSITVLRDG 219
Cdd:COG3839 199 TLADRIAVMNDG 210
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
274-485 |
7.58e-22 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 94.39 E-value: 7.58e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRqaiengLAYV----TEDR 349
Cdd:COG1121 17 GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLL--PPTSGTVRLFGKPPRRARRR------IGYVpqraEVDW 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 K---TAG-LVLIdNIKKNISLakLGKLSKN--QVIDENKEiQV-AEELRRKlNIksssilqktGNLSGGNQQKVVLSKWI 422
Cdd:COG1121 89 DfpiTVRdVVLM-GRYGRRGL--FRRPSRAdrEAVDEALE-RVgLEDLADR-PI---------GELSGGQQQRVLLARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:COG1121 155 AQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLV 217
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
5-236 |
8.17e-22 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 94.38 E-value: 8.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEvH-ALVGENGAGKSTLMSVLSG-IYPygSYSGDI-IFE---GNVcSFKDIKd 78
Cdd:COG1119 3 LLELRNVTVRRGGKTILDDISWTVKPGE-HwAILGPNGAGKSTLLSLITGdLPP--TYGNDVrLFGerrGGE-DVWELR- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 sEKIGIaiIHQELALIpylsigeniFLGNERAKNGIIN--------WNTT----HIKATEYLNRVGLKESSQTLIKDIGV 146
Cdd:COG1119 78 -KRIGL--VSPALQLR---------FPRDETVLDVVLSgffdsiglYREPtdeqRERARELLELLGLAHLADRPFGTLSQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 147 GKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSII-ISHKLNEVMkvaDSIT---VLRDGATI 222
Cdd:COG1119 146 GEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVlVTHHVEEIP---PGIThvlLLKDGRVV 222
|
250
....*....|....
gi 543000761 223 ETMVKDATVSEDRI 236
Cdd:COG1119 223 AAGPKEEVLTSENL 236
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
275-484 |
1.17e-21 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 91.54 E-value: 1.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraygkhitgkvkkdgkelllknvrqaienglayvtEDRKTAGL 354
Cdd:cd00267 11 GRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAG-----------------------------------LLKPTSGE 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNikKNISLAKLgklsknqvidenkeiqvaEELRRKLniksSSILQktgnLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:cd00267 56 ILIDG--KDIAKLPL------------------EELRRRI----GYVPQ----LSGGQRQRVALARALLLNPDLLLLDEP 107
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:cd00267 108 TSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
6-216 |
1.20e-21 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 98.13 E-value: 1.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGV-KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEKiGI 84
Cdd:TIGR02857 322 LEFSGVSVAYPGRrPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVD--PTEGSIAVNGVPLADADADSWRD-QI 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQeLALIPYLSIGENIFLGNERAKNGIINwntthikatEYLNRVGLKESSQTL-------IKDIG----VGKQQLVE 153
Cdd:TIGR02857 399 AWVPQ-HPFLFAGTIAENIRLARPDASDAEIR---------EALERAGLDEFVAALpqgldtpIGEGGaglsGGQAQRLA 468
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 154 IAKALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLnEVMKVADSITVL 216
Cdd:TIGR02857 469 LARAFLRDAPLLLLDEPTAHLDAE-TEAEVLEALRALAQGRTVLLVTHRL-ALAALADRIVVL 529
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
6-222 |
1.65e-21 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 92.82 E-value: 1.65e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGdiifEGNVCSFKDIKDSEKI--G 83
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLK--PTSG----RATVAGHDVVREPREVrrR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIF-------LGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:cd03265 75 IGIVFQDLSVDDELTGWENLYiharlygVPGAERRE----------RIDELLDFVGLLEAADRLVKTYSGGMRRRLEIAR 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 157 ALAKDVKLLILDEPTAALNEEDSDNL-LELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:cd03265 145 SLVHRPEVLFLDEPTIGLDPQTRAHVwEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRII 211
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
6-223 |
2.38e-21 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 93.15 E-value: 2.38e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPYgsySGDIIFEGNVCSFKDiKDSEKIGI 84
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLeTPD---SGQLNIAGHQFDFSQ-KPSEKAIR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 A------IIHQELALIPYLSIGENIF--------LGNERAKngiinwntthIKATEYLNRVGLKESSQTLIKDIGVGKQQ 150
Cdd:COG4161 79 LlrqkvgMVFQQYNLWPHLTVMENLIeapckvlgLSKEQAR----------EKAMKLLARLRLTDKADRFPLHLSGGQQQ 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 151 LVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:COG4161 149 RVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIE 221
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
276-486 |
2.57e-21 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 92.33 E-value: 2.57e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHIT-GKVKKDGKELLLKNVRQAIenglAYVTEDRKTAGL 354
Cdd:cd03234 20 ARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTsGQILFNGQPRKPDQFQKCV----AYVRQDDILLPG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKKNISLAKLGKLSKnqviDENKEIQVAEELRRKLNIKS--SSILQktgNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:cd03234 96 LTVRETLTYTAILRLPRKSS----DAIRKKRVEDVLLRDLALTRigGNLVK---GISGGERRRVSIAVQLLWDPKVLILD 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKsIIIISSELP--EILGMCDRIYVMNEGRIV 486
Cdd:cd03234 169 EPTSGLDSFTALNLVSTLSQLARRNR-IVILTIHQPrsDLFRLFDRILLLSSGEIV 223
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
20-233 |
2.66e-21 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 92.93 E-value: 2.66e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDiKDSEKIGIAIIHQELALIPYlSI 99
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYV--PENGRVLVDGHDLALAD-PAWLRRQVGVVLQENVLFNR-SI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 GENIFLGNERAKNGIINWNTTHIKATEYLNRvgLKESSQTLIKDIGV----GKQQLVEIAKALAKDVKLLILDEPTAALN 175
Cdd:cd03252 93 RDNIALADPGMSMERVIEAAKLAGAHDFISE--LPEGYDTIVGEQGAglsgGQRQRIAIARALIHNPRILIFDEATSALD 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 176 EEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIETMVKDATVSE 233
Cdd:cd03252 171 YE-SEHAIMRNMHDICAGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLAE 226
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
6-224 |
3.44e-21 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 96.84 E-value: 3.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsysgdiifEGNV----CSFKDI-KDS 79
Cdd:PRK11174 350 IEAEDLEILSPdGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPY---------QGSLkingIELRELdPES 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGIAIIHQELALiPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRV--GLkessQTLIKD----IGVGKQQLVE 153
Cdd:PRK11174 421 WRKHLSWVGQNPQL-PHGTLRDNVLLGNPDASDEQLQQALENAWVSEFLPLLpqGL----DTPIGDqaagLSVGQAQRLA 495
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 154 IAKALAKDVKLLILDEPTAALnEEDSDNLLELILELKKHGITSIIISHKLNEVMKVaDSITVLRDGATIET 224
Cdd:PRK11174 496 LARALLQPCQLLLLDEPTASL-DAHSEQLVMQALNAASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQQ 564
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-233 |
3.49e-21 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 93.63 E-value: 3.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKdseKIGi 84
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILA--PDSGEVLWDGEPLDPEDRR---RIG- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 aiihqelalipYL----------SIGENI-FLGneRAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVE 153
Cdd:COG4152 75 -----------YLpeerglypkmKVGEQLvYLA--RLKG--LSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 154 IAKALAKDVKLLILDEPTAALneeDSDNLLELILELKKH---GITSIIISHKLNEVMKVADSITVLRDGatieTMVKDAT 230
Cdd:COG4152 140 LIAALLHDPELLILDEPFSGL---DPVNVELLKDVIRELaakGTTVIFSSHQMELVEELCDRIVIINKG----RKVLSGS 212
|
...
gi 543000761 231 VSE 233
Cdd:COG4152 213 VDE 215
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
262-493 |
3.80e-21 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 92.56 E-value: 3.80e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 262 EINDWNV-FDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgRA---YGKHITGKVKKDGKEL---LLKNV 334
Cdd:COG1124 3 EVRNLSVsYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLL-----RAlagLERPWSGEVTFDGRPVtrrRRKAF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 335 RQAIenglAYVTED-------RKTaglvlidnIKKNIS--LAKLGKLsknqviDENKEIqvaEELRRKLNIkSSSILQKT 405
Cdd:COG1124 78 RRRV----QMVFQDpyaslhpRHT--------VDRILAepLRIHGLP------DREERI---AELLEQVGL-PPSFLDRY 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 406 GN-LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:COG1124 136 PHqLSGGQRQRVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLrEERGLTYLFVSHDLAVVAHLCDRVAVMQNG 215
|
250
....*....|
gi 543000761 484 RIVGELDQKD 493
Cdd:COG1124 216 RIVEELTVAD 225
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
16-222 |
1.05e-20 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 90.01 E-value: 1.05e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSekigIAIIHQELALIP 95
Cdd:cd03226 11 KGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIK--ESSGSILLNGKPIKAKERRKS----IGYVMQDVDYQL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YL-SIGENIFLGNERAKNGIInwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAAL 174
Cdd:cd03226 85 FTdSVREELLLGLKELDAGNE-------QAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGL 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 543000761 175 NEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:cd03226 158 DYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
1-224 |
1.54e-20 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 92.66 E-value: 1.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAefILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygsysGDIIFEGNVCSFKDI 76
Cdd:COG4170 1 MP--LLDIRNLTIEIDTpqgrVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITK-----DNWHVTADRFRWNGI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 77 ---KDSEK-----IG--IAIIHQELA--LIPYLSIG----ENIFlgNERAKNGIINW-NTTHIKATEYLNRVGLKESsqt 139
Cdd:COG4170 74 dllKLSPRerrkiIGreIAMIFQEPSscLDPSAKIGdqliEAIP--SWTFKGKWWQRfKWRKKRAIELLHRVGIKDH--- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 140 liKDI----------GVGkqQLVEIAKALAKDVKLLILDEPTAA---------------LNEedsdnllelilelkKHGI 194
Cdd:COG4170 149 --KDImnsyphelteGEC--QKVMIAMAIANQPRLLIADEPTNAmesttqaqifrllarLNQ--------------LQGT 210
|
250 260 270
....*....|....*....|....*....|
gi 543000761 195 TSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:COG4170 211 SILLISHDLESISQWADTITVLYCGQTVES 240
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
5-224 |
2.01e-20 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 92.45 E-value: 2.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGnvcsfKDIKD-S 79
Cdd:COG1135 1 MIELENLSKTFPTkggpVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPT--SGSVLVDG-----VDLTAlS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 E--------KIGiaIIHQELALIPYLSIGENIFLGNERAKngiinWNTTHIKA--TEYLNRVGLKESSQTLIKDIGVGKQ 149
Cdd:COG1135 74 ErelraarrKIG--MIFQHFNLLSSRTVAENVALPLEIAG-----VPKAEIRKrvAELLELVGLSDKADAYPSQLSGGQK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 150 QLVEIAKALAKDVKLLILDEPTAAL---------------NEEdsdnllelilelkkHGITSIIISHKLNEVMKVADSIT 214
Cdd:COG1135 147 QRVGIARALANNPKVLLCDEATSALdpettrsildllkdiNRE--------------LGLTIVLITHEMDVVRRICDRVA 212
|
250
....*....|
gi 543000761 215 VLRDGATIET 224
Cdd:COG1135 213 VLENGRIVEQ 222
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
273-486 |
2.10e-20 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 88.65 E-value: 2.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNVRQAIENgLAYVTedrkta 352
Cdd:cd03214 9 YGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAG--LLKPSSGEILLDGKDLASLSPKELARK-IAYVP------ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 glvlidnikknislaklgklsknQVIDEnkeIQVAEELRRKLNiksssilqktgNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:cd03214 80 -----------------------QALEL---LGLAHLADRPFN-----------ELSGGERQRVLLARALAQEPPILLLD 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLA-EEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03214 123 EPTSHLDIAHQIELLELLRRLArERGKTVVMVLHDLNLAARYADRVILLKDGRIV 177
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
275-484 |
2.12e-20 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 88.40 E-value: 2.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNVRQAIENGLayVTEDRKTAGL 354
Cdd:cd03229 12 QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLL---------RCIAGLEEPDSGSILIDGEDLTDLEDE--LPPLRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLID-------NIKKNISLAklgklsknqvidenkeiqvaeelrrklniksssilqktgnLSGGNQQKVVLSKWIFTDPE 427
Cdd:cd03229 81 VFQDfalfphlTVLENIALG----------------------------------------LSGGQQQRVALARALAMDPD 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 428 VLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:cd03229 121 VLLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
6-219 |
2.23e-20 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 89.57 E-value: 2.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypYGSYSGDIIFEGNVCSFKDIKDSEKiG 83
Cdd:cd03245 3 IEFRNVSFSYPNqeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGL--YKPTSGSVLLDGTDIRQLDPADLRR-N 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIpYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRvgLKESSQTLIKDIG----VGKQQLVEIAKALA 159
Cdd:cd03245 80 IGYVPQDVTLF-YGTLRDNITLGAPLADDERILRAAELAGVTDFVNK--HPNGLDLQIGERGrglsGGQRQAVALARALL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 160 KDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNeVMKVADSITVLRDG 219
Cdd:cd03245 157 NDPPILLLDEPTSAMDMN-SEERLKERLRQLLGDKTLIIITHRPS-LLDLVDRIIVMDSG 214
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
277-488 |
3.20e-20 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 87.48 E-value: 3.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKELLLKNVRQAIENGLAYVTEdrktaglvl 356
Cdd:cd03216 14 KALDGVSLSVRRGEVHALLGENGAGKSTL-MKILSGLY-KPDSGEILVDGKEVSFASPRDARRAGIAMVYQ--------- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 idnikknislaklgklsknqvidenkeiqvaeelrrklniksssilqktgnLSGGNQQKVVLSKWIFTDPEVLILDEPTR 436
Cdd:cd03216 83 ---------------------------------------------------LSVGERQMVEIARALARNARLLILDEPTA 111
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 543000761 437 GIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03216 112 ALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
5-219 |
3.31e-20 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 90.07 E-value: 3.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYpygsySGDIIFEGNVCSF----------- 73
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLI-----TGDKSAGSHIELLgrtvqregrla 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 74 KDIKDSeKIGIAIIHQELALIPYLSIGENIF---LGNERAKNGIINWNTTHIK--ATEYLNRVGLKESSQTLIKDIGVGK 148
Cdd:PRK09984 79 RDIRKS-RANTGYIFQQFNLVNRLSVLENVLigaLGSTPFWRTCFSWFTREQKqrALQALTRVGMVHFAHQRVSTLSGGQ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 149 QQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVALRQG 229
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
5-219 |
3.41e-20 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 89.66 E-value: 3.41e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI--KDSEKI 82
Cdd:COG0410 3 MLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLP--PRSGSIRFDG-----EDItgLPPHRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 ---GIAIIHQELALIPYLSIGENIFLGNERAKNGiinwntTHIKAT------------EYLNRVGlkessQTLikdIGvG 147
Cdd:COG0410 76 arlGIGYVPEGRRIFPSLTVEENLLLGAYARRDR------AEVRADlervyelfprlkERRRQRA-----GTL---SG-G 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 148 KQQLVEIAKALAKDVKLLILDEPT---------------AALNEEdsdnllelilelkkhGITSIIISHKLNEVMKVADS 212
Cdd:COG0410 141 EQQMLAIGRALMSRPKLLLLDEPSlglapliveeifeiiRRLNRE---------------GVTILLVEQNARFALEIADR 205
|
....*..
gi 543000761 213 ITVLRDG 219
Cdd:COG0410 206 AYVLERG 212
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
274-486 |
4.82e-20 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 89.08 E-value: 4.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYGKHiTGKVKKDGKELllknvrqaienGLAYVTEDRKTAG 353
Cdd:cd03252 13 DGPVILDNISLRIKPGEVVGIVGRSGSGKSTLT-KLIQRFYVPE-NGRVLVDGHDL-----------ALADPAWLRRQVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDN------IKKNISLAKLGkLSKNQVIdENKEIQVAEELRRKLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTDP 426
Cdd:cd03252 80 VVLQENvlfnrsIRDNIALADPG-MSMERVI-EAAKLAGAHDFISELPEGYDTIVGEQGaGLSGGQRQRIAIARALIHNP 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEIlgMC-DRIYVMNEGRIV 486
Cdd:cd03252 158 RILIFDEATSALDYESEHAIMRNMHDIC-AGRTVIIIAHRLSTV--KNaDRIIVMEKGRIV 215
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
274-486 |
8.37e-20 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 88.44 E-value: 8.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFgRAYGKHiTGKVKKDG---KELLLKNVRQAIenglAYVTEDrk 350
Cdd:cd03253 12 PGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLF-RFYDVS-SGSILIDGqdiREVTLDSLRRAI----GVVPQD-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 tagLVLI-DNIKKNISLAKLGKlSKNQVIDENKEIQVAEELRRkLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTDPEV 428
Cdd:cd03253 84 ---TVLFnDTIGYNIRYGRPDA-TDEEVIEAAKAAQIHDKIMR-FPDGYDTIVGERGlKLSGGEKQRVAIARAILKNPPI 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 429 LILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:cd03253 159 LLLDEATSALDTHTEREIQAALRDVS-KGRTTIVIAHRLSTIVN-ADKIIVLKDGRIV 214
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
6-224 |
1.01e-19 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 88.15 E-value: 1.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYpyGSYSGDIIFEGNVCSFKDIKDSEKI--- 82
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLE--MPRSGTLNIAGNHFDFSKTPSDKAIrel 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 --GIAIIHQELALIPYLSIGENIF--------LGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLV 152
Cdd:PRK11124 81 rrNVGMVFQQYNLWPHLTVQQNLIeapcrvlgLSKDQALA----------RAEKLLERLRLKPYADRFPLHLSGGQQQRV 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 153 EIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:PRK11124 151 AIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQ 222
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-229 |
1.84e-19 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 87.49 E-value: 1.84e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPYgsySGDIIFEGnvcsfKD 75
Cdd:COG4181 4 SSAPIIELRGLTKTVGTgageLTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLdRPT---SGTVRLAG-----QD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 76 IKD----------SEKIGIaiIHQELALIPYLSIGENIFL-----GNERAKNgiinwntthiKATEYLNRVGLKESSQTL 140
Cdd:COG4181 76 LFAldedararlrARHVGF--VFQSFQLLPTLTALENVMLplelaGRRDARA----------RARALLERVGLGHRLDHY 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 141 IKDIGVGKQQLVEIAKALAKDVKLLILDEPTA---------------ALNEEdsdnllelilelkkHGITSIIISHKlNE 205
Cdd:COG4181 144 PAQLSGGEQQRVALARAFATEPAILFADEPTGnldaatgeqiidllfELNRE--------------RGTTLVLVTHD-PA 208
|
250 260
....*....|....*....|....
gi 543000761 206 VMKVADSITVLRDGATIETMVKDA 229
Cdd:COG4181 209 LAARCDRVLRLRAGRLVEDTAATA 232
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
276-485 |
3.27e-19 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 86.39 E-value: 3.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFG---RAYgkhiTGKVKKDGKelllkNVRQAIENGLAYVTedRKTA 352
Cdd:cd03255 17 VQALKGVSLSIEKGEFVAIVGPSGSGKSTL-LNILGgldRPT----SGEVRVDGT-----DISKLSEKELAAFR--RRHI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GLV-----LID--NIKKNISLAKL--GKLSKnqvidENKEiqVAEELRRKLNIKSSsILQKTGNLSGGNQQKVVLSKWIF 423
Cdd:cd03255 85 GFVfqsfnLLPdlTALENVELPLLlaGVPKK-----ERRE--RAEELLERVGLGDR-LNHYPSELSGGQQQRVAIARALA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 424 TDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSElPEILGMCDRIYVMNEGRI 485
Cdd:cd03255 157 NDPKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHD-PELAEYADRIIELRDGKI 218
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
261-486 |
3.80e-19 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 86.47 E-value: 3.80e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 261 FEINDWNVFDpvvDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGR----AYGKHITGKVKKDGKELLLKNVRq 336
Cdd:cd03260 1 IELRDLNVYY---GDKHALKDISLDIPKGEITALIGPSGCGKSTL-LRLLNRlndlIPGAPDEGEVLLDGKDIYDLDVD- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 337 aienglayVTEDRKTAGLV-----LID-NIKKNISLA-KLGKLSKNQVIDEN-----KEIQVAEELRRKLNIKSssilqk 404
Cdd:cd03260 76 --------VLELRRRVGMVfqkpnPFPgSIYDNVAYGlRLHGIKLKEELDERveealRKAALWDEVKDRLHALG------ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 405 tgnLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:cd03260 142 ---LSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGR 217
|
..
gi 543000761 485 IV 486
Cdd:cd03260 218 LV 219
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
243-486 |
3.87e-19 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 90.66 E-value: 3.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 243 RDLVNRFPKREAKIGEIYFEindwNV---FDPvvDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGrAYgKHIT 319
Cdd:COG2274 458 REEGRSKLSLPRLKGDIELE----NVsfrYPG--DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLG-LY-EPTS 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 320 GKVKKDG---KELLLKNVRQAIenglAYVTEDrktaGLVLIDNIKKNISLAKLGkLSKNQVIDENKEIQVAEELRR---K 393
Cdd:COG2274 530 GRILIDGidlRQIDPASLRRQI----GVVLQD----VFLFSGTIRENITLGDPD-ATDEEIIEAARLAGLHDFIEAlpmG 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 394 LNiksSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELpEILGM 473
Cdd:COG2274 601 YD---TVVGEGGSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLL-KGRTVIIIAHRL-STIRL 675
|
250
....*....|...
gi 543000761 474 CDRIYVMNEGRIV 486
Cdd:COG2274 676 ADRIIVLDKGRIV 688
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
6-177 |
3.90e-19 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 85.71 E-value: 3.90e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGeVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEKIGIa 85
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTP--PSSGTIRIDGQDVLKQPQKLRRRIGY- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 iIHQELALIPYLSIGEniFLGNERAKNGIinwNTTHIKAT--EYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVK 163
Cdd:cd03264 77 -LPQEFGVYPNFTVRE--FLDYIAWLKGI---PSKEVKARvdEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPS 150
|
170
....*....|....
gi 543000761 164 LLILDEPTAALNEE 177
Cdd:cd03264 151 ILIVDEPTAGLDPE 164
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
6-223 |
4.47e-19 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 88.60 E-value: 4.47e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFKDIKDsEKIGia 85
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQT--SGHIRFHGTDVSRLHARD-RKVG-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLG------NERAKNGIINWntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALA 159
Cdd:PRK10851 78 FVFQHYALFRHMTVFDNIAFGltvlprRERPNAAAIKA-----KVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALA 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 160 KDVKLLILDEPTAALN---------------EEDSdnllelilelkkhgITSIIISHKLNEVMKVADSITVLRDGaTIE 223
Cdd:PRK10851 153 VEPQILLLDEPFGALDaqvrkelrrwlrqlhEELK--------------FTSVFVTHDQEEAMEVADRVVVMSQG-NIE 216
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
5-175 |
5.61e-19 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 86.68 E-value: 5.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGnvcsfKDIKD--SEKi 82
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQH--GSITLDG-----KPVEGpgAER- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 giAIIHQELALIPYLSIGENIFLGNERAknGIINWNTTHiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDV 162
Cdd:PRK11248 73 --GVVFQNEGLLPWRNVQDNVAFGLQLA--GVEKMQRLE-IAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANP 147
|
170
....*....|...
gi 543000761 163 KLLILDEPTAALN 175
Cdd:PRK11248 148 QLLLLDEPFGALD 160
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
275-488 |
5.86e-19 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 85.67 E-value: 5.86e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTelamSVFgraygKHITGKVKKDGKELLLKNvrQAIEN---------GLAYV 345
Cdd:cd03218 12 KRKVVNGVSLSVKQGEIVGLLGPNGAGKT----TTF-----YMIVGLVKPDSGKILLDG--QDITKlpmhkrarlGIGYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 346 TED----RKtagLVLIDNIkknISLAKLGKLSKNQVIDEnkeiqvAEELRRKLNIKSSSiLQKTGNLSGGNQQKVVLSKW 421
Cdd:cd03218 81 PQEasifRK---LTVEENI---LAVLEIRGLSKKEREEK------LEELLEEFHITHLR-KSKASSLSGGERRRVEIARA 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03218 148 LATNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAE 214
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
7-224 |
7.07e-19 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 89.64 E-value: 7.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPGVK-ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-PygsYSGDIIFEGNvcsfkDIKD----SE 80
Cdd:PRK13657 336 EFDDVSFSYDNSRqGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFdP---QSGRILIDGT-----DIRTvtraSL 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQElALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRvglKESS-QTLIKDIGV----GKQQLVEIA 155
Cdd:PRK13657 408 RRNIAVVFQD-AGLFNRSIEDNIRVGRPDATDEEMRAAAERAQAHDFIER---KPDGyDTVVGERGRqlsgGERQRLAIA 483
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 156 KALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVmKVADSITVLRDGATIET 224
Cdd:PRK13657 484 RALLKDPPILILDEATSALDVE-TEAKVKAALDELMKGRTTFIIAHRLSTV-RNADRILVFDNGRVVES 550
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
5-219 |
7.90e-19 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 84.02 E-value: 7.90e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITklfpGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGNVCSFKDIKDSEKIGI 84
Cdd:cd03215 4 VLEVRGLS----VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPP--ASGEITLDGKPVTRRSPRDAIRAGI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AII----HQElALIPYLSIGENIFLGNerakngiinwntthikateYLNrvGlkessqtlikdigvGKQQLVEIAKALAK 160
Cdd:cd03215 78 AYVpedrKRE-GLVLDLSVAENIALSS-------------------LLS--G--------------GNQQKVVLARWLAR 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03215 122 DPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEG 180
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
5-222 |
9.60e-19 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 84.73 E-value: 9.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLF----PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsFKDIKD-- 78
Cdd:cd03266 1 MITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLE--PDAGFATVDG----FDVVKEpa 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SEKIGIAIIHQELALIPYLSIGENI-FLG-----NERAKNGIINWNTTHIKATEYLNRVGlkessqtliKDIGVGKQQLV 152
Cdd:cd03266 75 EARRRLGFVSDSTGLYDRLTARENLeYFAglyglKGDELTARLEELADRLGMEELLDRRV---------GGFSTGMRQKV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 153 EIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:cd03266 146 AIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
279-435 |
1.44e-18 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 82.31 E-value: 1.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGkhITGKVKKDGKELLLKNvRQAIENGLAYVTED-----RKTAG 353
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSP--TEGTILLDGQDLTDDE-RKSLRKEIGYVFQDpqlfpRLTVR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 lvliDNIKKNISLAKLGKLSKNQVIDEnkeiqVAEELRRKlNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDE 433
Cdd:pfam00005 78 ----ENLRLGLLLKGLSKREKDARAEE-----ALEKLGLG-DLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDE 147
|
..
gi 543000761 434 PT 435
Cdd:pfam00005 148 PT 149
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
274-486 |
1.50e-18 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 84.59 E-value: 1.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYGKHiTGKVKKDG---KELLLKNVRQAIenglAYVTEDrk 350
Cdd:cd03251 13 DGPPVLRDISLDIPAGETVALVGPSGSGKSTLV-NLIPRFYDVD-SGRILIDGhdvRDYTLASLRRQI----GLVSQD-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 taglVLI--DNIKKNISLAKLGKlSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEV 428
Cdd:cd03251 85 ----VFLfnDTVAENIAYGRPGA-TREEVEEAARAANAHEFIMELPEGYDTVIGERGVKLSGGQRQRIAIARALLKDPPI 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 429 LILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:cd03251 160 LILDEATSALDTESERLVQAALERLM-KNRTTFVIAHRLSTIEN-ADRIVVLEDGKIV 215
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
275-486 |
1.94e-18 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 83.37 E-value: 1.94e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKKDGKELLLKNVRQAIenglayvtedrktaGL 354
Cdd:cd03213 21 GKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGVSGEVLINGRPLDKRSFRKII--------------GY 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIkknislaklgkLSKNQVIDENkeIQVAEELRrklniksssilqktgNLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:cd03213 87 VPQDDI-----------LHPTLTVRET--LMFAAKLR---------------GLSGGERKRVSIALELVSNPSLLFLDEP 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEEGKSIIII----SSelpEILGMCDRIYVMNEGRIV 486
Cdd:cd03213 139 TSGLDSSSALQVMSLLRRLADTGRTIICSihqpSS---EIFELFDKLLLLSQGRVI 191
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
274-486 |
2.61e-18 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 84.16 E-value: 2.61e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNVRQAIENGLAYVTEDRKTA- 352
Cdd:cd03256 12 NGKKALKDVSLSINPGEFVALIGPSGAGKSTLL---------RCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRRQIGm 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 ---GLVLIDNIK--KNISLAKLGKLSKNQVIDEN---KEIQVAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFT 424
Cdd:cd03256 83 ifqQFNLIERLSvlENVLSGRLGRRSTWRSLFGLfpkEEKQRALAALERVGL-LDKAYQRADQLSGGQQQRVAIARALMQ 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKLA-EEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03256 162 QPKLILADEPVASLDPASSRQVMDLLKRINrEEGITVIVSLHQVDLAREYADRIVGLKDGRIV 224
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
275-488 |
3.45e-18 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 83.04 E-value: 3.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG--RAYGKHITGKVKKDGKEL-LLKNVRQAIENGLAYvteDRKT 351
Cdd:cd03268 12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGliKPDSGEITFDGKSYQKNIeALRRIGALIEAPGFY---PNLT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 AglvlidniKKNISLAKLGKLSKNQVIDENKEIqVAEELRRKlniksssilQKTGNLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:cd03268 89 A--------RENLRLLARLLGIRKKRIDEVLDV-VGLKDSAK---------KKVKGFSLGMKQRLGIALALLGNPDLLIL 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03268 151 DEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEE 207
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
6-219 |
3.79e-18 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 83.32 E-value: 3.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNvcSFKDIKDSEKIG 83
Cdd:cd03263 1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPT--SGTAYINGY--SIRTDRKAARQS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENI-FLGneRAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDV 162
Cdd:cd03263 77 LGYCPQFDALFDELTVREHLrFYA--RLKG--LPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGP 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 163 KLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03263 153 SVLLLDEPTSGLDPA-SRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDG 208
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1-245 |
4.16e-18 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 83.79 E-value: 4.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEmrNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFKDIKDSE 80
Cdd:PRK10895 1 MATLTAK--NLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRD--AGNIIIDDEDISLLPLHARA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPYLSIGENIFLGNERAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:PRK10895 77 RRGIGYLPQEASIFRRLSVYDNLMAVLQIRDD--LSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATVSEDRIIKGM 240
Cdd:PRK10895 155 NPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVY 234
|
....*
gi 543000761 241 VGRDL 245
Cdd:PRK10895 235 LGEDF 239
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
6-219 |
4.41e-18 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 83.27 E-value: 4.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKAldNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSE--KIG 83
Cdd:COG3840 2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLP--PDSGRILWNG-----QDLTALPpaERP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIFLG---------NERAkngiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEI 154
Cdd:COG3840 73 VSMLFQENNLFPHLTVAQNIGLGlrpglkltaEQRA------------QVEQALERVGLAGLLDRLPGQLSGGQRQRVAL 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 155 AKALAKDVKLLILDEPTAAL---------------NEEdsdnllelilelkkHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:COG3840 141 ARCLVRKRPILLLDEPFSALdpalrqemldlvdelCRE--------------RGLTVLMVTHDPEDAARIADRVLLVADG 206
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
1-215 |
5.63e-18 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 84.78 E-value: 5.63e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPG-----------VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGn 69
Cdd:COG4608 3 MAEPLLEVRDLKKHFPVrgglfgrtvgvVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEE--PTSGEILFDG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 70 vcsfKDIKDSEKIGIAIIHQELALI---PYLS----------IGE-----NIFLGNERAKngiinwntthiKATEYLNRV 131
Cdd:COG4608 80 ----QDITGLSGRELRPLRRRMQMVfqdPYASlnprmtvgdiIAEplrihGLASKAERRE-----------RVAELLELV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 132 GLK---------ESSqtlikdiGvGKQQLVEIAKALAKDVKLLILDEPTAAL---------N------EEdsdnllelil 187
Cdd:COG4608 145 GLRpehadryphEFS-------G-GQRQRIGIARALALNPKLIVCDEPVSALdvsiqaqvlNlledlqDE---------- 206
|
250 260
....*....|....*....|....*...
gi 543000761 188 elkkHGITSIIISHKLNEVMKVADSITV 215
Cdd:COG4608 207 ----LGLTYLFISHDLSVVRHISDRVAV 230
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
5-282 |
5.65e-18 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 85.38 E-value: 5.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypYGSYSGDIIFEGnvcsfKDIKD--SEKI 82
Cdd:PRK09452 14 LVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGF--ETPDSGRIMLDG-----QDITHvpAENR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIAIIHQELALIPYLSIGENIFLGNERAKNGiinwnTTHIKA--TEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:PRK09452 87 HVNTVFQSYALFPHMTVFENVAFGLRMQKTP-----AAEITPrvMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 161 DVKLLILDEPTAAL---------NEedsdnlleLILELKKHGITSIIISHKLNEVMKVADSITVLRDGaTIEtmvKDATV 231
Cdd:PRK09452 162 KPKVLLLDESLSALdyklrkqmqNE--------LKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDG-RIE---QDGTP 229
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 232 SEdriikgmVGRDLVNRFPKReaKIGEIyfeindwNVFDPVV----DGKKVIKNV 282
Cdd:PRK09452 230 RE-------IYEEPKNLFVAR--FIGEI-------NIFDATVierlDEQRVRANV 268
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
269-488 |
5.71e-18 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 82.80 E-value: 5.71e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 269 FDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLlKNVRQAIENgLAYVTE- 347
Cdd:cd03266 11 FRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLL--EPDAGFATVDGFDVV-KEPAEARRR-LGFVSDs 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 348 ----DRKTAglvlidniKKNIS-LAKLGKLSKNQVIDEnkeiqvAEELRRKLNIKSSsILQKTGNLSGGNQQKVVLSKWI 422
Cdd:cd03266 87 tglyDRLTA--------RENLEyFAGLYGLKGDELTAR------LEELADRLGMEEL-LDRRVGGFSTGMRQKVAIARAL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03266 152 VHDPPVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYE 217
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
6-219 |
9.80e-18 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 84.39 E-value: 9.80e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypYGSYSGDIIFEGnvcsfKDIKDS--EKIG 83
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGL--EKPTEGQIFIDG-----EDVTHRsiQQRD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALIPYLSIGENIFLG--------NERAKngiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIA 155
Cdd:PRK11432 80 ICMVFQSYALFPHMSLGENVGYGlkmlgvpkEERKQ-----------RVKEALELVDLAGFEDRYVDQISGGQQQRVALA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 156 KALAKDVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK11432 149 RALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKG 213
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
274-486 |
1.14e-17 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 81.80 E-value: 1.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNVRqaiengLAYVTEDRKTAG 353
Cdd:cd03259 11 GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLL---------RLIAGLERPDSGEILIDGRD------VTGVPPERRNIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLID-------NIKKNISLA-KLGKLSKNQVidENKEIQVAEELRRKLNIKSssilqKTGNLSGGNQQKVVLSKWIFTD 425
Cdd:cd03259 76 MVFQDyalfphlTVAENIAFGlKLRGVPKAEI--RARVRELLELVGLEGLLNR-----YPHELSGGQQQRVALARALARE 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03259 149 PSLLLLDEPLSALDAKLREELREELKELqRELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
6-223 |
1.14e-17 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 85.84 E-value: 1.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGNvcsfkDIKDSEkig 83
Cdd:PRK11176 342 IEFRNVTFTYPGkeVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDI--DEGEILLDGH-----DLRDYT--- 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQELALipylsIGENIFLGNERAKNGI------------INWNTTHIKATEYLNRvgLKESSQTLIKDIGV----G 147
Cdd:PRK11176 412 LASLRNQVAL-----VSQNVHLFNDTIANNIayarteqysreqIEEAARMAYAMDFINK--MDNGLDTVIGENGVllsgG 484
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 148 KQQLVEIAKALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:PRK11176 485 QRQRIAIARALLRDSPILILDEATSALDTE-SERAIQAALDELQKNRTSLVIAHRLSTIEK-ADEILVVEDGEIVE 558
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
5-486 |
1.15e-17 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 86.06 E-value: 1.15e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLF----PGVKALDNVNLKVKSGEVHALVGENGAGKS-TLMSVLSGIYPYGS--YSGDI--------IFEGN 69
Cdd:PRK10261 12 VLAVENLNIAFmqeqQKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQAGGlvQCDKMllrrrsrqVIELS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 70 VCSFKDIKDSEKIGIAIIHQE--LALIPYLSIGENIF--------LGNERAKngiinwntthIKATEYLNRVGLKESSQT 139
Cdd:PRK10261 92 EQSAAQMRHVRGADMAMIFQEpmTSLNPVFTVGEQIAesirlhqgASREEAM----------VEAKRMLDQVRIPEAQTI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 140 LIK---DIGVGKQQLVEIAKALAKDVKLLILDEPTAALN---EEDSDNLLELILELKKHGItsIIISHKLNEVMKVADSI 213
Cdd:PRK10261 162 LSRyphQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDvtiQAQILQLIKVLQKEMSMGV--IFITHDMGVVAEIADRV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 214 TVLRDGATIET-MVKD-----------ATVSEDRIIKGMVGRDLVNRFP--------KREAKI-------GEIYFEINDW 266
Cdd:PRK10261 240 LVMYQGEAVETgSVEQifhapqhpytrALLAAVPQLGAMKGLDYPRRFPlislehpaKQEPPIeqdtvvdGEPILQVRNL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 267 NVFDPVVDG------KKV--IKNVNLKVHRGEVVGISGLMGSGRtelamSVFGRAYGKHI---TGKVKKDGK--ELLLKN 333
Cdd:PRK10261 320 VTRFPLRSGllnrvtREVhaVEKVSFDLWPGETLSLVGESGSGK-----STTGRALLRLVesqGGEIIFNGQriDTLSPG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 334 VRQAIENGLAYVTED-------RKTAGlvliDNIKKNISLAKLGKlsknqviDENKEIQVAEELRRkLNIKSSSILQKTG 406
Cdd:PRK10261 395 KLQALRRDIQFIFQDpyasldpRQTVG----DSIMEPLRVHGLLP-------GKAAAARVAWLLER-VGLLPEHAWRYPH 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK10261 463 EFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQI 542
|
.
gi 543000761 486 V 486
Cdd:PRK10261 543 V 543
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
276-486 |
1.28e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 83.17 E-value: 1.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRqaienglayVTEDRKTAGLV 355
Cdd:PRK13637 20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLL--KPTSGKIIIDGVDITDKKVK---------LSDIRKKVGLV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LI--------DNIKKNISLA--KLGkLSKNQVideNKEIQVAEELrrkLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFT 424
Cdd:PRK13637 89 FQypeyqlfeETIEKDIAFGpiNLG-LSEEEI---ENRVKRAMNI---VGLDYEDYKDKSPfELSGGQKRRVAIAGVVAM 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK13637 162 EPKILILDEPTAGLDPKGRDEILNKIKELHKEYNmTIILVSHSMEDVAKLADRIIVMNKGKCE 224
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
273-485 |
1.83e-17 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 81.02 E-value: 1.83e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVIKNVNLKVHRGEVVGISGLMGSGRtelamSVFGRA----YGKHiTGKVKKDGKELLLKNV---RQAIenglAYV 345
Cdd:COG4619 10 VGGKPILSPVSLTLEAGECVAITGPSGSGK-----STLLRAladlDPPT-SGEIYLDGKPLSAMPPpewRRQV----AYV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 346 tedRKTAGLVLiDNIKKNISLAKLgklSKNQVIDENKEIQVAEELRRklnikSSSILQK-TGNLSGGNQQKVVLSKWIFT 424
Cdd:COG4619 80 ---PQEPALWG-GTVRDNLPFPFQ---LRERKFDRERALELLERLGL-----PPDILDKpVERLSGGERQRLALIRALLL 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:COG4619 148 QPDVLLLDEPTSALDPENTRRVEELLREYlAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
275-488 |
1.86e-17 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 81.71 E-value: 1.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKELLLKNVRQAIENGLAyvtedRK---- 350
Cdd:cd03219 12 GLVALDDVSFSVRPGEIHGLIGPNGAGKTTL-FNLISGFL-RPTSGSVLFDGEDITGLPPHEIARLGIG-----RTfqip 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 --TAGLVLIDNIKknISLAKLGKLSKNQVIDENKEIQVAEE---------LRRKLNiksssilQKTGNLSGGNQQKVVLS 419
Cdd:cd03219 85 rlFPELTVLENVM--VAAQARTGSGLLLARARREEREARERaeellervgLADLAD-------RPAGELSYGQQRRLEIA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 420 KWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03219 156 RALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAE 224
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
5-222 |
1.87e-17 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 85.55 E-value: 1.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVL-------SGIYpygSYSGDIIFEGNVCSF 73
Cdd:PRK10535 4 LLELKDIRRSYPSgeeqVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILgcldkptSGTY---RVAGQDVATLDADAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 74 KDIKdSEKIGIaiIHQELALIPYLSIGEN-----IFLGNERAKNgiinwnttHIKATEYLNRVGLKESSQTLIKDIGVGK 148
Cdd:PRK10535 81 AQLR-REHFGF--IFQRYHLLSHLTAAQNvevpaVYAGLERKQR--------LLRAQELLQRLGLEDRVEYQPSQLSGGQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 149 QQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKlNEVMKVADSITVLRDGATI 222
Cdd:PRK10535 150 QQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHD-PQVAAQAERVIEIRDGEIV 222
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
262-486 |
2.19e-17 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 83.18 E-value: 2.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 262 EINDWNVFDPVVDGK-KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG--RAYGKhITGKVKKDGKELL------LK 332
Cdd:COG0444 3 EVRNLKVYFPTRRGVvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGllPPPGI-TSGEILFDGEDLLklsekeLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 333 NVRQaieNGLAYVTED-------RKTAGLVLIDNIKKNislaklGKLSKNQVIDEnkeiqvAEELRRKLNIKS-SSIL-- 402
Cdd:COG0444 82 KIRG---REIQMIFQDpmtslnpVMTVGDQIAEPLRIH------GGLSKAEARER------AIELLERVGLPDpERRLdr 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 403 ---QktgnLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIY 478
Cdd:COG0444 147 yphE----LSGGMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHDLGVVAEIADRVA 222
|
....*...
gi 543000761 479 VMNEGRIV 486
Cdd:COG0444 223 VMYAGRIV 230
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
20-223 |
2.33e-17 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 81.00 E-value: 2.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKdseKIG-------IAIIHQEla 92
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVE--LSSGSILIDG-----VDIS---KIGlhdlrsrISIIPQD-- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 93 liPYL---SIGENIFLGNERAKNGIInwntthikatEYLNRVGLKESSQTLIKDIG-----------VGKQQLVEIAKAL 158
Cdd:cd03244 87 --PVLfsgTIRSNLDPFGEYSDEELW----------QALERVGLKEFVESLPGGLDtvveeggenlsVGQRQLLCLARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 159 AKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:cd03244 155 LRKSKILVLDEATASVDPE-TDALIQKTIREAFKDCTVLTIAHRLDTIID-SDRILVLDKGRVVE 217
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
274-484 |
3.81e-17 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 78.96 E-value: 3.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYgKHITGKVKKDG---KELLLKNVRQAIenglAYVTEDrk 350
Cdd:cd03228 13 RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLL-KLLLRLY-DPTSGEILIDGvdlRDLDLESLRKNI----AYVPQD-- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 taglVLI--DNIKKNIslaklgklsknqvidenkeiqvaeelrrklniksssilqktgnLSGGNQQKVVLSKWIFTDPEV 428
Cdd:cd03228 85 ----PFLfsGTIRENI-------------------------------------------LSGGQRQRIAIARALLRDPPI 117
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 429 LILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILgMCDRIYVMNEGR 484
Cdd:cd03228 118 LILDEATSALDPETEALILEALRALA-KGKTVIVIAHRLSTIR-DADRIIVLDDGR 171
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
276-493 |
4.13e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 81.75 E-value: 4.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRQaienglaYVTEDRKTAGLV 355
Cdd:PRK13646 20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALL--KPTTGTVTVDDITITHKTKDK-------YIRPVRKRIGMV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LI--------DNIKKNIslaKLGKLSKNQVIDENKE--IQVAEELRRKLNIKSSSILQktgnLSGGNQQKVVLSKWIFTD 425
Cdd:PRK13646 91 FQfpesqlfeDTVEREI---IFGPKNFKMNLDEVKNyaHRLLMDLGFSRDVMSQSPFQ----MSGGQMRKIAIVSILAMN 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLA-EEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKD 493
Cdd:PRK13646 164 PDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKE 232
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
7-224 |
4.92e-17 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 82.16 E-value: 4.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPygsYSGDIIFEGnvcsfKDI---KD 78
Cdd:PRK11153 3 ELKNISKVFPQggrtIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLeRP---TSGRVLVDG-----QDLtalSE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SE------KIGiaIIHQELALIPYLSIGENIFLGNERAkngiiNWNTTHIKA--TEYLNRVGLKESSQTLIKDIGVGKQQ 150
Cdd:PRK11153 75 KElrkarrQIG--MIFQHFNLLSSRTVFDNVALPLELA-----GTPKAEIKArvTELLELVGLSDKADRYPAQLSGGQKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 151 LVEIAKALAKDVKLLILDEPTAAL---------------NEEdsdnllelilelkkHGITSIIISHKLNEVMKVADSITV 215
Cdd:PRK11153 148 RVAIARALASNPKVLLCDEATSALdpattrsilellkdiNRE--------------LGLTIVLITHEMDVVKRICDRVAV 213
|
....*....
gi 543000761 216 LRDGATIET 224
Cdd:PRK11153 214 IDAGRLVEQ 222
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
16-223 |
5.94e-17 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 79.97 E-value: 5.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYpyGSYSGDIIFEGnvcsfKDIK----DSEKIGIAIIHQEL 91
Cdd:cd03253 12 PGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFY--DVSSGSILIDG-----QDIRevtlDSLRRAIGVVPQDT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 92 ALIPYlSIGENIFLGNERAKNGIInwntthIKATEYLNR----VGLKESSQTLIKDIGV----GKQQLVEIAKALAKDVK 163
Cdd:cd03253 85 VLFND-TIGYNIRYGRPDATDEEV------IEAAKAAQIhdkiMRFPDGYDTIVGERGLklsgGEKQRVAIARAILKNPP 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 164 LLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:cd03253 158 ILLLDEATSALDTH-TEREIQAALRDVSKGRTTIVIAHRLSTIVN-ADKIIVLKDGRIVE 215
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
276-486 |
6.30e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 80.81 E-value: 6.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRQAIEN-GLAYVTEDRKTAGL 354
Cdd:PRK13632 22 NNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLL--KPQSGEIKIDGITISKENLKEIRKKiGIIFQNPDNQFIGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKknISLaklgklsKNQVIDENKEIQVAEELRRKLNIKSssILQKTG-NLSGGNQQKVVLSKWIFTDPEVLILDE 433
Cdd:PRK13632 100 TVEDDIA--FGL-------ENKKVPPKKMKDIIDDLAKKVGMED--YLDKEPqNLSGGQKQRVAIASVLALNPEIIIFDE 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 434 PTRGIDVGAKYEIYTIINKLAEEG-KSIIIISSELPEILgMCDRIYVMNEGRIV 486
Cdd:PRK13632 169 STSMLDPKGKREIKKIMVDLRKTRkKTLISITHDMDEAI-LADKVIVFSEGKLI 221
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
5-224 |
7.95e-17 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 83.31 E-value: 7.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGV-----KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIifegNVCSFKDIKDS 79
Cdd:TIGR03269 279 IIKVRNVSKRYISVdrgvvKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLE--PTSGEV----NVRVGDEWVDM 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIG----------IAIIHQELALIPYLSIGEN------IFLGNERAKngiinwntthIKATEYLNRVGLKESSQTLIKD 143
Cdd:TIGR03269 353 TKPGpdgrgrakryIGILHQEYDLYPHRTVLDNlteaigLELPDELAR----------MKAVITLKMVGFDEEKAEEILD 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 144 -----IGVGKQQLVEIAKALAKDVKLLILDEPTAALNE-EDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLR 217
Cdd:TIGR03269 423 kypdeLSEGERHRVALAQVLIKEPRIVILDEPTGTMDPiTKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMR 502
|
....*..
gi 543000761 218 DGATIET 224
Cdd:TIGR03269 503 DGKIVKI 509
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
5-239 |
8.28e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 80.51 E-value: 8.28e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKD---IKDSE 80
Cdd:PRK13639 1 ILETRDLKYSYPdGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILK--PTSGEVLIKGEPIKYDKkslLEVRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAI-----------IHQELALIPYlsigeNIFLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQ 149
Cdd:PRK13639 79 TVGIVFqnpddqlfaptVEEDVAFGPL-----NLGLSKEEVEK----------RVKEALKAVGMEGFENKPPHHLSGGQK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 150 QLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDA 229
Cdd:PRK13639 144 KRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKE 223
|
250
....*....|
gi 543000761 230 TVSEDRIIKG 239
Cdd:PRK13639 224 VFSDIETIRK 233
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
6-224 |
9.23e-17 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 79.96 E-value: 9.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLS---GIYPYGSYSGDIIFEGNVCSFKDIKDSEKi 82
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNrliELYPEARVSGEVYLDGQDIFKMDVIELRR- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIAIIHQELALIPYLSIGENIFLG---NERAKNGI-----INWNTTHIKA-TEYLNRVGLKESSqtlikdIGVGKQQLVE 153
Cdd:PRK14247 83 RVQMVFQIPNPIPNLSIFENVALGlklNRLVKSKKelqerVRWALEKAQLwDEVKDRLDAPAGK------LSGGQQQRLC 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 154 IAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHgITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:PRK14247 157 IARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIVEW 226
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
275-485 |
1.69e-16 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 78.34 E-value: 1.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRtelamSVFGRAygkhITGKVKKDGKELLLKNVRqaIENGLAYVTEDRKTAGL 354
Cdd:cd03262 12 DFHVLKGIDLTVKKGEVVVIIGPSGSGK-----STLLRC----INLLEEPDSGTIIIDGLK--LTDDKKNINELRQKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLID-------NIKKNISLA--KLGKLSKNQVIDEnkeiqvAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTD 425
Cdd:cd03262 81 VFQQfnlfphlTVLENITLApiKVKGMSKAEAEER------ALELLEKVGL-ADKADAYPAQLSGGQQQRVAIARALAMN 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 426 PEVLILDEPTRGID---VGakyEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:cd03262 154 PKVMLFDEPTSALDpelVG---EVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
279-484 |
1.97e-16 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 80.54 E-value: 1.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGR-AYGKHITGKVKKDGKELLlkNVRQAIENGL-----AYVTEDRKTA 352
Cdd:PRK09473 32 VNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLlAANGRIGGSATFNGREIL--NLPEKELNKLraeqiSMIFQDPMTS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 ---GLVLIDNIKKNISLAKlgKLSKNQVIDENKEIQVA---EELRRKLNIKSSSilqktgnLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK09473 110 lnpYMRVGEQLMEVLMLHK--GMSKAEAFEESVRMLDAvkmPEARKRMKMYPHE-------FSGGMRQRVMIAMALLCRP 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:PRK09473 181 KLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 239
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
277-488 |
2.04e-16 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 78.77 E-value: 2.04e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRQAIENGLAYVTEDRKTAGLVL 356
Cdd:PRK11614 19 QALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDP--RATSGRIVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 IDNikkniSLAKLGKLSKNQVIDEnkEIQVAEELRRKLNIKSSsilQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTR 436
Cdd:PRK11614 97 VEE-----NLAMGGFFAERDQFQE--RIKWVYELFPRLHERRI---QRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSL 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 543000761 437 GIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK11614 167 GLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLE 218
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
278-486 |
2.26e-16 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 78.53 E-value: 2.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRT---ELAMSVFgraygKHITGKVKKDGKELLLKNvrqAIENGLAYVTEDRktaGL 354
Cdd:cd03299 14 KLKNVSLEVERGDYFVILGPTGSGKSvllETIAGFI-----KPDSGKILLNGKDITNLP---PEKRDISYVPQNY---AL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKKNISLAkLGKLSKNQVIDENKEIQVAEelrrKLNIksSSIL-QKTGNLSGGNQQKVVLSKWIFTDPEVLILDE 433
Cdd:cd03299 83 FPHMTVYKNIAYG-LKKRKVDKKEIERKVLEIAE----MLGI--DHLLnRKPETLSGGEQQRVAIARALVVNPKILLLDE 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 434 PTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03299 156 PFSALDVRTKEKLREELKKIRKEfGVTVLHVTHDFEEAWALADKVAIMLNGKLI 209
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
6-219 |
3.02e-16 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 78.57 E-value: 3.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypyGSYSGDIIFEGNVcSFKDIKDSekigIA 85
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGL---ETPSAGELLAGTA-PLAEARED----TR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLGneraKNGiiNWNTthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLL 165
Cdd:PRK11247 85 LMFQDARLLPWKKVIDNVGLG----LKG--QWRD---AALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 166 ILDEPTAALNE----EDSDnllELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK11247 156 LLDEPLGALDAltriEMQD---LIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEG 210
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
257-486 |
3.11e-16 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 78.04 E-value: 3.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 257 GEIYFEiNDWNVFDPvvdGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDG---KELLLKN 333
Cdd:cd03254 1 GEIEFE-NVNFSYDE---KKPVLKDINFSIKPGETVAIVGPTGAGKTTL-INLLMRFY-DPQKGQILIDGidiRDISRKS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 334 VRqaieNGLAYVTEDRktagLVLIDNIKKNISLAKLGKlSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQ 413
Cdd:cd03254 75 LR----SMIGVVLQDT----FLFSGTIMENIRLGRPNA-TDEEVIEAAKEAGAHDFIMKLPNGYDTVLGENGGNLSQGER 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 414 QKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLaEEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:cd03254 146 QLLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKL-MKGRTSIIIAHRLSTIKN-ADKILVLDDGKII 216
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
274-488 |
3.23e-16 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 81.36 E-value: 3.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYgkHIT-GKVKKDG---KELLLKNVRQAIenglAYVTEDr 349
Cdd:COG1132 351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLV-NLLLRFY--DPTsGRILIDGvdiRDLTLESLRRQI----GVVPQD- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 ktaGLVLIDNIKKNISLAKLGkLSKNQVIDENKEIQVAEELRR---KLNikssSILQKTG-NLSGGNQQKVVLSKWIFTD 425
Cdd:COG1132 423 ---TFLFSGTIRENIRYGRPD-ATDEEVEEAAKAAQAHEFIEAlpdGYD----TVVGERGvNLSGGQRQRIAIARALLKD 494
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILgMCDRIYVMNEGRIVGE 488
Cdd:COG1132 495 PPILILDEATSALDTETEALIQEALERLM-KGRTTIVIAHRLSTIR-NADRILVLDDGRIVEQ 555
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-219 |
3.61e-16 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 78.00 E-value: 3.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGiYPYGSySGDIIFEGnvcsfKDIKD-- 78
Cdd:PRK11614 1 MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCG-DPRAT-SGRIVFDG-----KDITDwq 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SEKI---GIAIIHQELALIPYLSIGENIFLGNERAKNgiinwntthikaTEYLNRVG--------LKESSQTLIKDIGVG 147
Cdd:PRK11614 74 TAKImreAVAIVPEGRRVFSRMTVEENLAMGGFFAER------------DQFQERIKwvyelfprLHERRIQRAGTMSGG 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 148 KQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK11614 142 EQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENG 213
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
6-220 |
3.68e-16 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 76.10 E-value: 3.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKA--LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGnvcsfKDIK--DSEK 81
Cdd:cd03246 1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTS--GRVRLDG-----ADISqwDPNE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 82 IG--IAIIHQELALIPYlSIGENIFLGNERakngiinwntthikateylNRVGLkessqtlikdigvgkqqlveiAKALA 159
Cdd:cd03246 74 LGdhVGYLPQDDELFSG-SIAENILSGGQR-------------------QRLGL---------------------ARALY 112
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 160 KDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLnEVMKVADSITVLRDGA 220
Cdd:cd03246 113 GNPRILVLDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRP-ETLASADRILVLEDGR 172
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
276-486 |
3.68e-16 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 77.63 E-value: 3.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDG---KELLLKNVRQAIenglAYVTEDrkta 352
Cdd:cd03245 17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTL-LKLLAGLY-KPTSGSVLLDGtdiRQLDPADLRRNI----GYVPQD---- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 gLVLI-DNIKKNISLAKLgkLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTDPEVLI 430
Cdd:cd03245 87 -VTLFyGTLRDNITLGAP--LADDERILRAAELAGVTDFVNKHPNGLDLQIGERGrGLSGGQRQAVALARALLNDPPILL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 431 LDEPTRGIDVGAKYEiytIINKLAE--EGKSIIIISSELPeILGMCDRIYVMNEGRIV 486
Cdd:cd03245 164 LDEPTSAMDMNSEER---LKERLRQllGDKTLIIITHRPS-LLDLVDRIIVMDSGRIV 217
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
274-488 |
3.72e-16 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 77.71 E-value: 3.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLL--KNVRQAIENGLAYVtedRKT 351
Cdd:COG1127 16 GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLL---------KLIIGLLRPDSGEILVdgQDITGLSEKELYEL---RRR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 AGLV-----LID--NIKKNIS--LAKLGKLSKNQVIDenkeiQVAEELRRkLNIkSSSILQKTGNLSGGNQQKVVLSKWI 422
Cdd:COG1127 84 IGMLfqggaLFDslTVFENVAfpLREHTDLSEAEIRE-----LVLEKLEL-VGL-PGAADKMPSELSGGMRKRVALARAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:COG1127 157 ALDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAE 223
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
3-174 |
5.14e-16 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 77.31 E-value: 5.14e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 3 EFILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGS-YSGDIIFEGNVCSFKDIK 77
Cdd:cd03234 1 QRVLPWWDVGLKAKNwnkyARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGtTSGQILFNGQPRKPDQFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 78 DSekigIAIIHQELALIPYLSIGE-----NIFLGNERAKNGIInwntTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLV 152
Cdd:cd03234 81 KC----VAYVRQDDILLPGLTVREtltytAILRLPRKSSDAIR----KKRVEDVLLRDLALTRIGGNLVKGISGGERRRV 152
|
170 180
....*....|....*....|..
gi 543000761 153 EIAKALAKDVKLLILDEPTAAL 174
Cdd:cd03234 153 SIAVQLLWDPKVLILDEPTSGL 174
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
5-232 |
5.70e-16 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 79.08 E-value: 5.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYpygsySGDIIFEGNVCSFKDI---- 76
Cdd:PRK15093 3 LLDIRNLTIEFKTsdgwVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVT-----KDNWRVTADRMRFDDIdllr 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 77 ---KDSEKI---GIAIIHQE--LALIPYLSIGENI--------FLGNERAKngiINWNttHIKATEYLNRVGLKESSQTL 140
Cdd:PRK15093 78 lspRERRKLvghNVSMIFQEpqSCLDPSERVGRQLmqnipgwtYKGRWWQR---FGWR--KRRAIELLHRVGIKDHKDAM 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 141 IK---DIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSI-IISHKLNEVMKVADSITVL 216
Cdd:PRK15093 153 RSfpyELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTIlLISHDLQMLSQWADKINVL 232
|
250
....*....|....*.
gi 543000761 217 RDGATIETMVKDATVS 232
Cdd:PRK15093 233 YCGQTVETAPSKELVT 248
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
274-488 |
6.16e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 78.11 E-value: 6.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMsvfgraygkHITGKVKKDGKELLLKNVRQAIENGLAYVtedRKTAG 353
Cdd:PRK13644 13 DGTPALENINLVIKKGEYIGIIGKNGSGKSTLAL---------HLNGLLRPQKGKVLVSGIDTGDFSKLQGI---RKLVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLidnikKNISLAKLGKLSKNQVIDENKEIQVAE-ELRRKLNIKSSSI-LQK-----TGNLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK13644 81 IVF-----QNPETQFVGRTVEEDLAFGPENLCLPPiEIRKRVDRALAEIgLEKyrhrsPKTLSGGQGQCVALAGILTMEP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEiLGMCDRIYVMNEGRIVGE 488
Cdd:PRK13644 156 ECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEE-LHDADRIIVMDRGKIVLE 216
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
6-219 |
6.38e-16 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 77.46 E-value: 6.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG-IYPygsYSGDIIFEGnvcsfKDIKDsekigi 84
Cdd:COG4559 2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGeLTP---SSGEVRLNG-----RPLAA------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 aIIHQELALI------------PYlSIGENIFLGneRAKNGIINWNTTHIkATEYLNRVGLKE----SSQTLikdIGvGK 148
Cdd:COG4559 68 -WSPWELARRravlpqhsslafPF-TVEEVVALG--RAPHGSSAAQDRQI-VREALALVGLAHlagrSYQTL---SG-GE 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 149 QQLVEIAKALA---KDV----KLLILDEPTAALneeDsdnllelilelKKH--------------GITSIIISHKLNEVM 207
Cdd:COG4559 139 QQRVQLARVLAqlwEPVdggpRWLFLDEPTSAL---D-----------LAHqhavlrlarqlarrGGGVVAVLHDLNLAA 204
|
250
....*....|..
gi 543000761 208 KVADSITVLRDG 219
Cdd:COG4559 205 QYADRILLLHQG 216
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
275-486 |
6.83e-16 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 77.24 E-value: 6.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRQAIENGLAYVTEDRKT-AG 353
Cdd:PRK10895 15 GRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIV--PRDAGNIIIDDEDISLLPLHARARRGIGYLPQEASIfRR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLAKlgKLSKNQVIDEnkeiqvAEELRRKLNIksSSILQKTG-NLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:PRK10895 93 LSVYDNLMAVLQIRD--DLSAEQREDR------ANELMEEFHI--EHLRDSMGqSLSGGERRRVEIARALAANPKFILLD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK10895 163 EPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLI 216
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
5-220 |
8.78e-16 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 76.36 E-value: 8.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLF---PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEK 81
Cdd:cd03248 11 IVKFQNVTFAYptrPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQ--PQGGQVLLDGKPISQYEHKYLHS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 82 IgIAIIHQElaliPYL---SIGENIFLG-----NERAKNGIINWNT-THIK--ATEYLNRVGLKESSqtlikdIGVGKQQ 150
Cdd:cd03248 89 K-VSLVGQE----PVLfarSLQDNIAYGlqscsFECVKEAAQKAHAhSFISelASGYDTEVGEKGSQ------LSGGQKQ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 151 LVEIAKALAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGA 220
Cdd:cd03248 158 RVAIARALIRNPQVLILDEATSALDAE-SEQQVQQALYDWPERRTVLVIAHRLSTVER-ADQILVLDGGR 225
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
279-486 |
9.70e-16 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 77.30 E-value: 9.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKELL------LKNVRqaienglayvtedRKTA 352
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTL-LRCINRLI-EPTSGKVLIDGQDIAamsrkeLRELR-------------RKKI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GLV-----------LIDNIKKNISLaklgklsknQVIDENKEIQVAEELRRKLNIKSSSiLQKTGNLSGGNQQKVVLSKW 421
Cdd:cd03294 105 SMVfqsfallphrtVLENVAFGLEV---------QGVPRAEREERAAEALELVGLEGWE-HKYPDELSGGMQQRVGLARA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03294 175 LAVDPDILLMDEAFSALDPLIRREMQDELLRLqAELQKTIVFITHDLDEALRLGDRIAIMKDGRLV 240
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
19-219 |
1.02e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 77.40 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSE---KIGIAIIHQELALIP 95
Cdd:PRK13637 21 KALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLK--PTSGKIIIDGVDITDKKVKLSDirkKVGLVFQYPEYQLFE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YlSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGLKESSqtlIKD-----IGVGKQQLVEIAKALAKDVKLLILDEP 170
Cdd:PRK13637 99 E-TIEKDIAFG---PINLGLSEEEIENRVKRAMNIVGLDYED---YKDkspfeLSGGQKRRVAIAGVVAMEPKILILDEP 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 171 TAALNEEDSDNLLELILEL-KKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK13637 172 TAGLDPKGRDEILNKIKELhKEYNMTIILVSHSMEDVAKLADRIIVMNKG 221
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
274-486 |
1.07e-15 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 75.75 E-value: 1.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRaygKHIT-GKVKKDGKELllkNVRQAIENGLAYVTED---- 348
Cdd:cd03301 11 GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGL---EEPTsGRIYIGGRDV---TDLPPKDRDIAMVFQNyaly 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 -RKTAglvlIDNIKKNISLAKLGKLS-KNQVIDENKEIQVAEELRRKlniksssilqkTGNLSGGNQQKVVLSKWIFTDP 426
Cdd:cd03301 85 pHMTV----YDNIAFGLKLRKVPKDEiDERVREVAELLQIEHLLDRK-----------PKQLSGGQRQRVALGRAIVREP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03301 150 KVFLMDEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
6-233 |
1.19e-15 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 76.43 E-value: 1.19e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFKDIKDSEKIGIA 85
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPD--SGKILLDGQDITKLPMHKRARLGIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLGNERAKNGIINWnttHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLL 165
Cdd:cd03218 79 YLPQEASIFRKLTVEENILAVLEIRGLSKKER---EEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFL 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 166 ILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG-----ATIETMVKDATVSE 233
Cdd:cd03218 156 LLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGkvlaeGTPEEIAANELVRK 228
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
16-223 |
1.22e-15 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 79.77 E-value: 1.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-PYGsysGDIIFEGnvcsfKDIKDSEKigiAIIHQELALI 94
Cdd:TIGR00958 492 PDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYqPTG---GQVLLDG-----VPLVQYDH---HYLHRQVALV 560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 ---PYL---SIGENIFLGNERAKNGIInwnTTHIKATEYLNRVGlkESSQTLIKDIG-------VGKQQLVEIAKALAKD 161
Cdd:TIGR00958 561 gqePVLfsgSVRENIAYGLTDTPDEEI---MAAAKAANAHDFIM--EFPNGYDTEVGekgsqlsGGQKQRIAIARALVRK 635
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 162 VKLLILDEPTAALneeDSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:TIGR00958 636 PRVLILDEATSAL---DAECEQLLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVE 693
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
274-486 |
1.24e-15 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 79.38 E-value: 1.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYgKHITGKVKKDG---KELLLKNVRqaieNGLAYVTEDrk 350
Cdd:TIGR02203 343 RDRPALDSISLVIEPGETVALVGRSGSGKSTLV-NLIPRFY-EPDSGQILLDGhdlADYTLASLR----RQVALVSQD-- 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 tagLVLI-DNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVL 429
Cdd:TIGR02203 415 ---VVLFnDTIANNIAYGRTEQADRAEIERALAAAYAQDFVDKLPLGLDTPIGENGVLLSGGQRQRLAIARALLKDAPIL 491
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 430 ILDEPTRGIDVGAKYEIYTIINKLaEEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:TIGR02203 492 ILDEATSALDNESERLVQAALERL-MQGRTTLVIAHRLSTIEK-ADRIVVMDDGRIV 546
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
8-219 |
1.58e-15 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 80.06 E-value: 1.58e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 8 MRNITKLFP--GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSekigIA 85
Cdd:TIGR01257 931 VKNLVKIFEpsGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLP--PTSGTVLVGG-----KDIETN----LD 999
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIP-------YLSIGENI-FLGNERAKngiiNWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKA 157
Cdd:TIGR01257 1000 AVRQSLGMCPqhnilfhHLTVAEHIlFYAQLKGR----SWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIA 1075
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 158 LAKDVKLLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:TIGR01257 1076 FVGDAKVVVLDEPTSGVDPY-SRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQG 1136
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
21-219 |
1.96e-15 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 75.62 E-value: 1.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPYgsySGDIIFEGNVCSF------KDIKDSEkigIAIIHQELAL 93
Cdd:PRK11629 25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLdTPT---SGDVIFNGQPMSKlssaakAELRNQK---LGFIYQFHHL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 IPYLSIGENI----FLGNERAKNgiinwntTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDE 169
Cdd:PRK11629 99 LPDFTALENVamplLIGKKKPAE-------INSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADE 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 543000761 170 PTAALNEEDSDNL-LELILELKKHGITSIIISHKLNEVMKVADSITvLRDG 219
Cdd:PRK11629 172 PTGNLDARNADSIfQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLE-MRDG 221
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
277-488 |
2.04e-15 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 75.47 E-value: 2.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFG---RAYgkhiTGKVKKDGKELLLKNvrqaiENGLAYVTedRKTAG 353
Cdd:COG1136 22 TALRGVSLSIEAGEFVAIVGPSGSGKSTL-LNILGgldRPT----SGEVLIDGQDISSLS-----ERELARLR--RRHIG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LV-----LID--NIKKNISLA-KLGKLSKNQVIDEnkeiqvAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTD 425
Cdd:COG1136 90 FVfqffnLLPelTALENVALPlLLAGVSRKERRER------ARELLERVGL-GDRLDHRPSQLSGGQQQRVAIARALVNR 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSElPEILGMCDRIYVMNEGRIVGE 488
Cdd:COG1136 163 PKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHD-PELAARADRVIRLRDGRIVSD 225
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
276-493 |
2.14e-15 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 76.38 E-value: 2.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKEL--LLKNVRQAIENGLAYVTED----- 348
Cdd:TIGR02769 24 APVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLE--KPAQGTVSFRGQDLyqLDRKQRRAFRRDVQLVFQDspsav 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 --RKTAGLVLIDNIKKNISLaklgklsknqviDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDP 426
Cdd:TIGR02769 102 npRMTVRQIIGEPLRHLTSL------------DESEQKARIAELLDMVGLRSEDADKLPRQLSGGQLQRINIARALAVKP 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKD 493
Cdd:TIGR02769 170 KLIVLDEAVSNLDMVLQAVILELLRKLqQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQ 237
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
5-181 |
2.30e-15 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 75.16 E-value: 2.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFP-----GVK--ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLsgiypYGSY---SGDIIFEgnvcsfk 74
Cdd:COG4778 4 LLEVENLSKTFTlhlqgGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCI-----YGNYlpdSGSILVR------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 75 diKDSEKIGIAII--HQELAL----IPYLSIgeniFL-------------------GNERAkngiinwnTTHIKATEYLN 129
Cdd:COG4778 72 --HDGGWVDLAQAspREILALrrrtIGYVSQ----FLrviprvsaldvvaepllerGVDRE--------EARARARELLA 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 130 RVGLKES---------SqtlikdiGvGKQQLVEIAKALAKDVKLLILDEPTAALneeDSDN 181
Cdd:COG4778 138 RLNLPERlwdlppatfS-------G-GEQQRVNIARGFIADPPLLLLDEPTASL---DAAN 187
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
274-486 |
2.45e-15 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 75.23 E-value: 2.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVfgraygkhITGKVKKDGKELL-----LKNVRQAIENGLAYVTED 348
Cdd:cd03263 13 GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTT-LKM--------LTGELRPTSGTAYingysIRTDRKAARQSLGYCPQF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 RktaglVLIDN--IKKNISL-AKLGKLSKNQVIDEnkeiqvAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTD 425
Cdd:cd03263 84 D-----ALFDEltVREHLRFyARLKGLPKSEIKEE------VELLLRVLGL-TDKANKRARTLSGGMKRKLSLAIALIGG 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03263 152 PSVLLLDEPTSGLDPASRRAIWDLILEVR-KGRSIILTTHSMDEAEALCDRIAIMSDGKLR 211
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
262-488 |
3.73e-15 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 77.88 E-value: 3.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 262 EINDWNVFDPvvDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG--RAYgkhiTGKVKKDGKELL---LKNVRQ 336
Cdd:COG4988 338 ELEDVSFSYP--GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGflPPY----SGSILINGVDLSdldPASWRR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 337 AIenglAYVTEDrktaGLVLIDNIKKNISLAKlGKLSKNQVIDENKEIQVAEELRR---KLNikssSILQKTG-NLSGGN 412
Cdd:COG4988 412 QI----AWVPQN----PYLFAGTIRENLRLGR-PDASDEELEAALEAAGLDEFVAAlpdGLD----TPLGEGGrGLSGGQ 478
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 413 QQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELpEILGMCDRIYVMNEGRIVGE 488
Cdd:COG4988 479 AQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA-KGRTVILITHRL-ALLAQADRILVLDDGRIVEQ 552
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
3-228 |
4.22e-15 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 77.00 E-value: 4.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 3 EFILEMrniTKLFPGVKaldNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKD--IKDS 79
Cdd:PRK10070 32 EQILEK---TGLSLGVK---DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIE--PTRGQVLIDGvDIAKISDaeLREV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGIAIIHQELALIPYLSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALA 159
Cdd:PRK10070 104 RRKKIAMVFQSFALMPHMTVLDNTAFGMELAG---INAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALA 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 160 KDVKLLILDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKD 228
Cdd:PRK10070 181 INPDILLMDEAFSALDPLiRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPD 250
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
26-219 |
4.52e-15 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 74.07 E-value: 4.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 26 LKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEkigIAIIHQELALIPYLSIGENIFL 105
Cdd:cd03298 19 LTFAQGEITAIVGPSGSGKSTLLNLIAGFET--PQSGRVLINGVDVTAAPPADRP---VSMLFQENNLFAHLTVEQNVGL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 106 GneraKNGIINWNTTHIKATE-YLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLE 184
Cdd:cd03298 94 G----LSPGLKLTAEDRQAIEvALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLD 169
|
170 180 190
....*....|....*....|....*....|....*.
gi 543000761 185 LILELKKH-GITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03298 170 LVLDLHAEtKMTVLMVTHQPEDAKRLAQRVVFLDNG 205
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
6-174 |
5.06e-15 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 74.81 E-value: 5.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG-IYPygsYSGDIIFEGnvcsfKDIKDSEkigi 84
Cdd:PRK13548 3 LEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGeLSP---DSGEVRLNG-----RPLADWS---- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 aiiHQELALI------------PYlSIGENIFLGneRAKNGIINWNTTHIkATEYLNRVGLKESSQTLIKDIGVGKQQLV 152
Cdd:PRK13548 71 ---PAELARRravlpqhsslsfPF-TVEEVVAMG--RAPHGLSRAEDDAL-VAAALAQVDLAHLAGRDYPQLSGGEQQRV 143
|
170 180
....*....|....*....|....*...
gi 543000761 153 EIAKALA------KDVKLLILDEPTAAL 174
Cdd:PRK13548 144 QLARVLAqlwepdGPPRWLLLDEPTSAL 171
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
274-486 |
5.50e-15 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 74.64 E-value: 5.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKELLLKNV---RQAIenglAYVTEDrk 350
Cdd:cd03295 12 GGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTT-MKMINRLI-EPTSGEIFIDGEDIREQDPvelRRKI----GYVIQQ-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 tAGLVLIDNIKKNISLakLGKLSKnqvIDENKEIQVAEELRRKLNIKSSSILQK-TGNLSGGNQQKVVLSKWIFTDPEVL 429
Cdd:cd03295 84 -IGLFPHMTVEENIAL--VPKLLK---WPKEKIRERADELLALVGLDPAEFADRyPHELSGGQQQRVGVARALAADPPLL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 430 ILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03295 158 LMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGEIV 215
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
275-488 |
5.72e-15 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 74.30 E-value: 5.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTelamSVFgraYgkHITGKVKKDGKELLLKNvrQAIEN---------GLAYV 345
Cdd:COG1137 15 KRTVVKDVSLEVNQGEIVGLLGPNGAGKT----TTF---Y--MIVGLVKPDSGRIFLDG--EDITHlpmhkrarlGIGYL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 346 TED----RKtagLVLIDNIKkniSLAKLGKLSKNQVIDEnkeiqvAEELRRKLNIksSSIL-QKTGNLSGGNQQKVVLSK 420
Cdd:COG1137 84 PQEasifRK---LTVEDNIL---AVLELRKLSKKEREER------LEELLEEFGI--THLRkSKAYSLSGGERRRVEIAR 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 421 WIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:COG1137 150 ALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHNVRETLGICDRAYIISEGKVLAE 217
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
274-486 |
7.30e-15 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 73.81 E-value: 7.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKEL--LLKNVRQAienglayvtedrkt 351
Cdd:cd03300 11 GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAG--FETPTSGEILLDGKDItnLPPHKRPV-------------- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 aGLVLID-------NIKKNISLA-KLGKLSKNQVIDENKEI--QVA-EELRRKlniksssilqKTGNLSGGNQQKVVLSK 420
Cdd:cd03300 75 -NTVFQNyalfphlTVFENIAFGlRLKKLPKAEIKERVAEAldLVQlEGYANR----------KPSQLSGGQQQRVAIAR 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 421 WIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03300 144 ALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKElGITFVFVTHDQEEALTMSDRIAVMNKGKIQ 210
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
10-223 |
7.50e-15 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 74.75 E-value: 7.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 10 NITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGS---YSGDIIFEG-NVCSFKDIKDSEKiGIA 85
Cdd:PRK14271 26 NLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSgyrYSGDVLLGGrSIFNYRDVLEFRR-RVG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPyLSIGENIFLGNERAKngIINWNTTHIKATEYLNRVGLKESSQTLIKD----IGVGKQQLVEIAKALAKD 161
Cdd:PRK14271 105 MLFQRPNPFP-MSIMDNVLAGVRAHK--LVPRKEFRGVAQARLTEVGLWDAVKDRLSDspfrLSGGQQQLLCLARTLAVN 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 162 VKLLILDEPTAALNEEDSDNLLELILELKKHgITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK14271 182 PEVLLLDEPTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFDGRLVE 242
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
6-170 |
7.73e-15 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 73.95 E-value: 7.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGnvcsfKDIKDSE----- 80
Cdd:COG0396 1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKYEVTSGSILLDG-----EDILELSpdera 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPYLSIGEniFLgnERAKNGI----INWNTTHIKATEYLNRVGLKESsqTLIKDIGV----GKQQLV 152
Cdd:COG0396 76 RAGIFLAFQYPVEIPGVSVSN--FL--RTALNARrgeeLSAREFLKLLKEKMKELGLDED--FLDRYVNEgfsgGEKKRN 149
|
170
....*....|....*...
gi 543000761 153 EIAKALAKDVKLLILDEP 170
Cdd:COG0396 150 EILQMLLLEPKLAILDET 167
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
276-488 |
7.87e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 74.84 E-value: 7.87e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNVRQAIENglayVTEDRKTAGLV 355
Cdd:PRK13652 17 KEALNNINFIAPRNSRIAVIGPNGAGKSTLF---------RHFNGILKPTSGSVLIRGEPITKEN----IREVRKFVGLV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LID--------NIKKNISLAKLgklskNQVIDENKEIQVAEELRRKLNIksSSILQKT-GNLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK13652 84 FQNpddqifspTVEQDIAFGPI-----NLGLDEETVAHRVSSALHMLGL--EELRDRVpHHLSGGEKKRVAIAGVIAMEP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK13652 157 QVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAY 219
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
274-488 |
7.88e-15 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 73.56 E-value: 7.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTE-------LAMSVFGRAygkHITG-KVKKDGKElllknVRQAIENGLAYV 345
Cdd:cd03265 11 GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTtikmlttLLKPTSGRA---TVAGhDVVREPRE-----VRRRIGIVFQDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 346 TEDRKTAGLvliDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLniksssilqkTGNLSGGNQQKVVLSKWIFTD 425
Cdd:cd03265 83 SVDDELTGW---ENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRL----------VKTYSGGMRRRLEIARSLVHR 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03265 150 PEVLFLDEPTIGLDPQTRAHVWEYIEKLkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAE 213
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-222 |
8.03e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 74.88 E-value: 8.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKD---I 76
Cdd:PRK13636 1 MEDYILKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILK--PSSGRILFDGKPIDYSRkglM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 77 KDSEKIGIAIIHQELALIPyLSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:PRK13636 79 KLRESVGMVFQDPDNQLFS-ASVYQDVSFG---AVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAG 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 157 ALAKDVKLLILDEPTAALNEED-SDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13636 155 VLVMEPKVLVLDEPTAGLDPMGvSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
273-486 |
8.74e-15 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 72.94 E-value: 8.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKKDGKELLLKNVrqaienglayvtEDRKTA 352
Cdd:cd03217 10 VGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEVTEGEILFKGEDITDLPP------------EERARL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GLVLIDNIKKNISLAKLgklsknqvidenkeiqvaEELRRKLNIksssilqktgNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:cd03217 78 GIFLAFQYPPEIPGVKN------------------ADFLRYVNE----------GFSGGEKKRNEILQLLLLEPDLAILD 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKSIIIIsSELPEILGMC--DRIYVMNEGRIV 486
Cdd:cd03217 130 EPDSGLDIDALRLVAEVINKLREEGKSVLII-THYQRLLDYIkpDRVHVLYDGRIV 184
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
272-487 |
9.61e-15 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 73.10 E-value: 9.61e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 272 VVDGKKVIKNVNLKVH---RGEVVGISGLMGSGRTELAMSVFG--RAYGkhitGKVKKDGKELllknvrQAIENGLAYVT 346
Cdd:cd03297 3 CVDIEKRLPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGleKPDG----GTIVLNGTVL------FDSRKKINLPP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 347 EDRKTaGLVLID-------NIKKNISLAkLGKLSKNQvidenKEIQVAEELRRkLNIksSSIL-QKTGNLSGGNQQKVVL 418
Cdd:cd03297 73 QQRKI-GLVFQQyalfphlNVRENLAFG-LKRKRNRE-----DRISVDELLDL-LGL--DHLLnRYPAQLSGGEKQRVAL 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVG 487
Cdd:cd03297 143 ARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQY 212
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
277-486 |
9.77e-15 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 73.22 E-value: 9.77e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFgrAYGKHITGKVKKDGKELLLKNVrQAIENGLAYVTEDRktagLVL 356
Cdd:cd03369 22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALF--RFLEAEEGKIEIDGIDISTIPL-EDLRSSLTIIPQDP----TLF 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 IDNIKKNISlaklgklsknqVIDENKEIQVAEELRrklnIKSSSIlqktgNLSGGNQQKVVLSKWIFTDPEVLILDEPTR 436
Cdd:cd03369 95 SGTIRSNLD-----------PFDEYSDEEIYGALR----VSEGGL-----NLSQGQRQLLCLARALLKRPRVLVLDEATA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 437 GIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:cd03369 155 SIDYATDALIQKTIREEF-TNSTILTIAHRLRTIID-YDKILVMDAGEVK 202
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
274-486 |
1.16e-14 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 73.92 E-value: 1.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELL---LKNVRQAIenglAYVTEDRK 350
Cdd:COG1120 12 GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAG--LLKPSSGEVLLDGRDLAslsRRELARRI----AYVPQEPP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 TAGlvlidnikkNIS------------LAKLGKLSKnqvidenKEIQVAEELRRKLNIksSSILQKT-GNLSGGNQQKVV 417
Cdd:COG1120 86 APF---------GLTvrelvalgryphLGLFGRPSA-------EDREAVEEALERTGL--EHLADRPvDELSGGERQRVL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 418 LSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLA-EEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG1120 148 IARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLArERGRTVVMVLHDLNLAARYADRLVLLKDGRIV 217
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
274-488 |
1.25e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 73.96 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMsvfgraygkHITGKVKKDGKELLLKNvrQAIENGLAYVTEDRKTAG 353
Cdd:PRK13639 13 DGTEALKGINFKAEKGEMVALLGPNGAGKSTLFL---------HFNGILKPTSGEVLIKG--EPIKYDKKSLLEVRKTVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLID--------NIKKNISLAKLG-KLSKNQVidenkEIQVAEELRRklnIKSSSILQKT-GNLSGGNQQKVVLSKWIF 423
Cdd:PRK13639 82 IVFQNpddqlfapTVEEDVAFGPLNlGLSKEEV-----EKRVKEALKA---VGMEGFENKPpHHLSGGQKKRVAIAGILA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 424 TDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK13639 154 MKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKE 218
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
268-488 |
1.55e-14 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 73.00 E-value: 1.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 268 VFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNVRQaienglayVTE 347
Cdd:cd03258 10 VFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCING--LERPTSGSVLVDGTDLTLLSGKE--------LRK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 348 DRKTAGLV-----LIDN--IKKNISLA-KLGKLSKNQVIdenkeiQVAEELRRKLNI--KSSSilqKTGNLSGGNQQKVV 417
Cdd:cd03258 80 ARRRIGMIfqhfnLLSSrtVFENVALPlEIAGVPKAEIE------ERVLELLELVGLedKADA---YPAQLSGGQKQRVG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 418 LSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:cd03258 151 IARALANNPKVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEE 222
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-174 |
1.74e-14 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 73.58 E-value: 1.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLF-PG----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDI-KD 78
Cdd:COG1101 1 MLELKNLSKTFnPGtvneKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLP--PDSGSILIDG-----KDVtKL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SEkigiaiiHQELALI------------PYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRV-----GLKESSQTLI 141
Cdd:COG1101 74 PE-------YKRAKYIgrvfqdpmmgtaPSMTIEENLALAYRRGKRRGLRRGLTKKRRELFRELLatlglGLENRLDTKV 146
|
170 180 190
....*....|....*....|....*....|...
gi 543000761 142 KDIGVGKQQLVEIAKALAKDVKLLILDEPTAAL 174
Cdd:COG1101 147 GLLSGGQRQALSLLMATLTKPKLLLLDEHTAAL 179
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
274-486 |
1.98e-14 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 73.20 E-value: 1.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGR---AYGKHIT--GKVKkdGKElllkNVRqaienglayvtED 348
Cdd:COG1119 14 GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDlppTYGNDVRlfGERR--GGE----DVW-----------EL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 RKTAGLV---LIDNIKKNISlaklgklsknqVID----------------ENKEIQVAEELRRKLNIksSSILQKT-GNL 408
Cdd:COG1119 77 RKRIGLVspaLQLRFPRDET-----------VLDvvlsgffdsiglyrepTDEQRERARELLELLGL--AHLADRPfGTL 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 409 SGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEG-KSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG1119 144 SQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGRVV 222
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
6-223 |
2.04e-14 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 72.86 E-value: 2.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYS---GDIIFEGNvcsfKDIKDSEKI 82
Cdd:PRK11264 4 IEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTirvGDITIDTA----RSLSQQKGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 ------GIAIIHQELALIPYLSIGENIFLGNERAKNgiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:PRK11264 80 irqlrqHVGFVFQNFNLFPHRTVLENIIEGPVIVKG--EPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 157 ALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK11264 158 ALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVE 224
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
274-486 |
2.22e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 73.34 E-value: 2.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMsvfgraygkHITGKVKKDGKELLLKNvrQAIENGLAYVTEDRKTAG 353
Cdd:PRK13636 17 DGTHALKGININIKKGEVTAILGGNGAGKSTLFQ---------NLNGILKPSSGRILFDG--KPIDYSRKGLMKLRESVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQK--TGNLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:PRK13636 86 MVFQDPDNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDkpTHCLSFGQKKRVAIAGVLVMEPKVLVL 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK13636 166 DEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
275-486 |
2.26e-14 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 72.86 E-value: 2.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTEL--AMSVFGRAYGKHIT-GKVKKDGKELLLKNVRQaienglayVTEDRKT 351
Cdd:PRK11264 15 GQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLlrCINLLEQPEAGTIRvGDITIDTARSLSQQKGL--------IRQLRQH 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 AGLVLidnikKNISL----AKLGKLSKNQVIDENKEIQVAEELRRKLniksssiLQKTG----------NLSGGNQQKVV 417
Cdd:PRK11264 87 VGFVF-----QNFNLfphrTVLENIIEGPVIVKGEPKEEATARAREL-------LAKVGlagketsyprRLSGGQQQRVA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 418 LSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK11264 155 IARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIV 223
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
6-223 |
2.66e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 73.32 E-value: 2.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLF-PGV----KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFE------GNVcSFK 74
Cdd:PRK13641 3 IKFENVDYIYsPGTpmekKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYhitpetGNK-NLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 75 DIKdsEKIGIAIIHQELALIpylsigENIFLgnERAKNGIINWNTTH----IKATEYLNRVGLKESsqtLIK----DIGV 146
Cdd:PRK13641 82 KLR--KKVSLVFQFPEAQLF------ENTVL--KDVEFGPKNFGFSEdeakEKALKWLKKVGLSED---LISkspfELSG 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 147 GKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK13641 149 GQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIK 225
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
15-201 |
3.11e-14 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 71.30 E-value: 3.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 15 FP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSEKiGIAIIHQELAL 93
Cdd:TIGR01166 1 YPgGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLR--PQSGAVLIDG-----EPLDYSRK-GLLERRQRVGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 --------IPYLSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLL 165
Cdd:TIGR01166 73 vfqdpddqLFAADVDQDVAFG---PLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVL 149
|
170 180 190
....*....|....*....|....*....|....*.
gi 543000761 166 ILDEPTAALNEEDSDNLLELILELKKHGITSIIISH 201
Cdd:TIGR01166 150 LLDEPTAGLDPAGREQMLAILRRLRAEGMTVVISTH 185
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
19-223 |
3.24e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 73.12 E-value: 3.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG--IYPYG-SYSGDIIFEGNVCSFKDIKDSEK-IGIAIIHQELALI 94
Cdd:PRK13645 25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGliISETGqTIVGDYAIPANLKKIKEVKRLRKeIGLVFQFPEYQLF 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 PYlSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGL-KESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAA 173
Cdd:PRK13645 105 QE-TIEKDIAFG---PVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGG 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 174 LN---EEDSDNLLELILELKKHGItsIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK13645 181 LDpkgEEDFINLFERLNKEYKKRI--IMVTHNMDQVLRIADEVIVMHEGKVIS 231
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
18-219 |
3.61e-14 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 71.98 E-value: 3.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPygsYSGDIIFEGNVCSFKDIKDSEKIGIaIIHQELALIPY 96
Cdd:cd03267 34 VEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLlQP---TSGEVRVAGLVPWKRRKKFLRRIGV-VFGQKTQLWWD 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 97 LSIGENIFLgnerakngiiNWNTTHIKATEYLNRvgLKESSQTL---------IKDIGVGKQQLVEIAKALAKDVKLLIL 167
Cdd:cd03267 110 LPVIDSFYL----------LAAIYDLPPARFKKR--LDELSELLdleelldtpVRQLSLGQRMRAEIAAALLHEPEILFL 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 168 DEPTAALNEEDSDNLLE-LILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03267 178 DEPTIGLDVVAQENIRNfLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKG 230
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
6-219 |
3.67e-14 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 74.11 E-value: 3.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSFKDIKDSEKIgIA 85
Cdd:PRK09536 4 IDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTA--GTVLVAGDDVEALSARAASRR-VA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENIFLGNERAKNGIINWNTTHIKATEY-LNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:PRK09536 81 SVPQDTSLSFEFDVRQVVEMGRTPHRSRFDTWTETDRAAVERaMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPV 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 165 LILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK09536 161 LLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADG 215
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
282-488 |
4.61e-14 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 73.61 E-value: 4.61e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 282 VNLKVHRGEVVGISGLMGSGRTEL--AMSVFGRAYGKHIT--GKVKKDG-KELLLKNVRQAIenglAYVTEDrktAGLVL 356
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLirLIAGLTRPDEGEIVlnGRTLFDSrKGIFLPPEKRRI----GYVFQE---ARLFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 IDNIKKNISLAKLGKLSKNQVIDENKEIQVaeelrrkLNIksSSILQK-TGNLSGGNQQKVVLSKWIFTDPEVLILDEPT 435
Cdd:TIGR02142 89 HLSVRGNLRYGMKRARPSERRISFERVIEL-------LGI--GHLLGRlPGRLSGGEKQRVAIGRALLSSPRLLLMDEPL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 436 RGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:TIGR02142 160 AALDDPRKYEILPYLERLHAEfGIPILYVSHSLQEVLRLADRVVVLEDGRVAAA 213
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
278-485 |
5.47e-14 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 69.94 E-value: 5.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKEL---LLKNVRQAIenglAYVTEDRKTAGL 354
Cdd:cd03246 17 VLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTS--GRVRLDGADIsqwDPNELGDHV----GYLPQDDELFSG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIkknislaklgklsknqvidenkeiqvaeelrrklniksssilqktgnLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:cd03246 91 SIAENI-----------------------------------------------LSGGQRQRLGLARALYGNPRILVLDEP 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEEGKSIIIISSElPEILGMCDRIYVMNEGRI 485
Cdd:cd03246 124 NSHLDVEGERALNQAIAALKAAGATRIVIAHR-PETLASADRILVLEDGRV 173
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
6-223 |
5.86e-14 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 70.03 E-value: 5.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGiyPYGSYSGDIIFEGNVCSfkDIKDSEKIG 83
Cdd:cd03247 1 LSINNVSFSYPEqeQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTG--DLKPQQGEITLDGVPVS--DLEKALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQElaliPYLsigeniflgnerakngiinWNTThikateYLNRVGLKESSqtlikdigvGKQQLVEIAKALAKDVK 163
Cdd:cd03247 77 ISVLNQR----PYL-------------------FDTT------LRNNLGRRFSG---------GERQRLALARILLQDAP 118
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 164 LLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEvMKVADSITVLRDGATIE 223
Cdd:cd03247 119 IVLLDEPTVGLDPI-TERQLLSLIFEVLKDKTLIWITHHLTG-IEHMDKILFLENGKIIM 176
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
268-490 |
8.19e-14 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 70.58 E-value: 8.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 268 VFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVfgraygkhITGKVKKDGKELLLknvrqaieNGlAYVTE 347
Cdd:cd03293 9 TYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTL-LRI--------IAGLERPTSGEVLV--------DG-EPVTG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 348 DRKTAGLVLID-------NIKKNISLA-KLGKLSKNQVIDEnkeiqvAEELRRKLNiksssiLQKTGN-----LSGGNQQ 414
Cdd:cd03293 71 PGPDRGYVFQQdallpwlTVLDNVALGlELQGVPKAEARER------AEELLELVG------LSGFENayphqLSGGMRQ 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 415 KVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNE--GRIVGELD 490
Cdd:cd03293 139 RVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIwRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVAEVE 217
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-228 |
8.41e-14 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 71.50 E-value: 8.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFKDIKD-S 79
Cdd:PRK11701 2 MDQPLLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPD--AGEVHYRMRDGQLRDLYAlS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 E-------KIGIAIIHQELA--LIPYLSIGENIflgNER-AKNGIINWNTTHIKATEYLNRVglkESSQTLIKDI----- 144
Cdd:PRK11701 80 EaerrrllRTEWGFVHQHPRdgLRMQVSAGGNI---GERlMAVGARHYGDIRATAGDWLERV---EIDAARIDDLpttfs 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 145 GvGKQQLVEIAKALAKDVKLLILDEPTAALneedsDNLLELILELKKHGITS------IIISHKLNEVMKVADSITVLRD 218
Cdd:PRK11701 154 G-GMQQRLQIARNLVTHPRLVFMDEPTGGL-----DVSVQARLLDLLRGLVRelglavVIVTHDLAVARLLAHRLLVMKQ 227
|
250
....*....|
gi 543000761 219 GATIETMVKD 228
Cdd:PRK11701 228 GRVVESGLTD 237
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
275-486 |
8.43e-14 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 73.65 E-value: 8.43e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYGKHiTGKVKKDG---KELLLKNVRQAIenglAYVTEDrkt 351
Cdd:COG4987 347 GRPVLDGLSLTLPPGERVAIVGPSGSGKSTLL-ALLLRFLDPQ-SGSITLGGvdlRDLDEDDLRRRI----AVVPQR--- 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 aglVLI--DNIKKNISLAKLGklsknqvIDENKEIQVAE---------ELRRKLNikssSILQKTG-NLSGGNQQKVVLS 419
Cdd:COG4987 418 ---PHLfdTTLRENLRLARPD-------ATDEELWAALErvglgdwlaALPDGLD----TWLGEGGrRLSGGERRRLALA 483
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 420 KWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEiLGMCDRIYVMNEGRIV 486
Cdd:COG4987 484 RALLRDAPILLLDEPTEGLDAATEQALLADLLEAL-AGRTVLLITHRLAG-LERMDRILVLEDGRIV 548
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
2-201 |
9.02e-14 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 70.58 E-value: 9.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITK-LFPG---VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPyGSySGDIIFEGNVCSFKDIK 77
Cdd:PRK10584 3 AENIVEVHHLKKsVGQGeheLSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDD-GS-SGEVSLVGQPLHQMDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 78 DSEKI---GIAIIHQELALIPYLSIGENIFL-GNERAKNGiinwNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVE 153
Cdd:PRK10584 81 ARAKLrakHVGFVFQSFMLIPTLNALENVELpALLRGESS----RQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVA 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 543000761 154 IAKALAKDVKLLILDEPTAALNEEDSDNLLELI-LELKKHGITSIIISH 201
Cdd:PRK10584 157 LARAFNGRPDVLFADEPTGNLDRQTGDKIADLLfSLNREHGTTLILVTH 205
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
274-491 |
1.04e-13 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 71.68 E-value: 1.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTEL---AMSVFgraygKHITGKVKKDGKELLLKNVRQaiengLAYVTEDRk 350
Cdd:COG4152 12 GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTiriILGIL-----APDSGEVLWDGEPLDPEDRRR-----IGYLPEER- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 taGL-----VlIDNIkknISLAKLGKLSKNQVIDEnkeiqvAEELRRKLNIKSSsILQKTGNLSGGNQQKVVLskwIFT- 424
Cdd:COG4152 81 --GLypkmkV-GEQL---VYLARLKGLSKAEAKRR------ADEWLERLGLGDR-ANKKVEELSKGNQQKVQL---IAAl 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 425 --DPEVLILDEPTRGID-VGAKyEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV--GELDQ 491
Cdd:COG4152 145 lhDPELLILDEPFSGLDpVNVE-LLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVlsGSVDE 215
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
274-486 |
1.19e-13 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 73.21 E-value: 1.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNvRQAIENGLAYVTEDRktag 353
Cdd:PRK10790 352 DDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMG--YYPLTEGEIRLDGRPLSSLS-HSVLRQGVAMVQQDP---- 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLAKlgKLSKNQVIDENKEIQVAEeLRRKLNIKSSSILQKTGN-LSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:PRK10790 425 VVLADTFLANVTLGR--DISEEQVWQALETVQLAE-LARSLPDGLYTPLGEQGNnLSVGQKQLLALARVLVQTPQILILD 501
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 433 EPTRGIDVGAKYEIYTIInKLAEEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:PRK10790 502 EATANIDSGTEQAIQQAL-AAVREHTTLVVIAHRLSTIVE-ADTILVLHRGQAV 553
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
5-219 |
1.28e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 71.17 E-value: 1.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDSEKI 82
Cdd:PRK13644 1 MIRLENVSYSYPdGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLR--PQKGKVLVSGiDTGDFSKLQGIRKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 -GIAIIHQELALIPYlSIGENIFLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKD 161
Cdd:PRK13644 79 vGIVFQNPETQFVGR-TVEEDLAFGPE---NLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTME 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 162 VKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEvMKVADSITVLRDG 219
Cdd:PRK13644 155 PECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEE-LHDADRIIVMDRG 211
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
6-203 |
1.32e-13 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 73.16 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG-VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDSEKIG 83
Cdd:TIGR02868 335 LELRDLSAGYPGaPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLD--PLQGEVTLDGvPVSSLDQDEVRRRVS 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IaiihqeLALIPYL---SIGENIFLGNERAkngiinwntTHIKATEYLNRVGL-------KESSQTLIKDIGV----GKQ 149
Cdd:TIGR02868 413 V------CAQDAHLfdtTVRENLRLARPDA---------TDEELWAALERVGLadwlralPDGLDTVLGEGGArlsgGER 477
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 150 QLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKhGITSIIISHKL 203
Cdd:TIGR02868 478 QRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALS-GRTVVLITHHL 530
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
21-223 |
1.33e-13 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 73.21 E-value: 1.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSfkdiKDSEKI---GIAIIHQELALIPYl 97
Cdd:PRK10790 357 LQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLT--EGEIRLDGRPLS----SLSHSVlrqGVAMVQQDPVVLAD- 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 98 SIGENIFLGNERAKNGIinWNTTHIKATEYLNRvGLKESSQTLIKDIG----VGKQQLVEIAKALAKDVKLLILDEPTAA 173
Cdd:PRK10790 430 TFLANVTLGRDISEEQV--WQALETVQLAELAR-SLPDGLYTPLGEQGnnlsVGQKQLLALARVLVQTPQILILDEATAN 506
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 174 LNEEDSDNLLELILELKKHgITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:PRK10790 507 IDSGTEQAIQQALAAVREH-TTLVVIAHRLSTIVE-ADTILVLHRGQAVE 554
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
1-219 |
1.71e-13 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 70.38 E-value: 1.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSgiYPYGSYSGDIIFEGNVCSFKDIKDSE 80
Cdd:PRK10619 1 MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCIN--FLEKPSEGSIVVNGQTINLVRDKDGQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 ------------KIGIAIIHQELALIPYLSIGENIF------LGNERAKngiinwntTHIKATEYLNRVGLKESSQTLIK 142
Cdd:PRK10619 79 lkvadknqlrllRTRLTMVFQHFNLWSHMTVLENVMeapiqvLGLSKQE--------ARERAVKYLAKVGIDERAQGKYP 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 143 -DIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK10619 151 vHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQG 228
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
277-501 |
1.90e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 70.89 E-value: 1.90e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMS--------------VFGRAYGKHITGKVKKDGKELLLKNVRQaieNGL 342
Cdd:PRK13651 21 KALDNVSVEINQGEFIAIIGQTGSGKTTFIEHlnalllpdtgtiewIFKDEKNKKKTKEKEKVLEKLVIQKTRF---KKI 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 343 AYVTEDRKTAGLVLI--------DNIKKNISLAKLG-KLSKNQvidenkeiqvAEELRRKLnIK----SSSILQKTG-NL 408
Cdd:PRK13651 98 KKIKEIRRRVGVVFQfaeyqlfeQTIEKDIIFGPVSmGVSKEE----------AKKRAAKY-IElvglDESYLQRSPfEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 409 SGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVge 488
Cdd:PRK13651 167 SGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDGKII-- 244
|
250
....*....|...
gi 543000761 489 ldqKDASQESIMK 501
Cdd:PRK13651 245 ---KDGDTYDILS 254
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
5-251 |
2.10e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 71.03 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG-----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYP--YGS------YSGD-IIFEGNV 70
Cdd:PRK13631 21 ILRVKNLYCVFDEkqeneLVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKskYGTiqvgdiYIGDkKNNHELI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 71 CSF--KDIKDSEKIG--IAIIHQ--ELALIPYlSIGENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIK-D 143
Cdd:PRK13631 101 TNPysKKIKNFKELRrrVSMVFQfpEYQLFKD-TIEKDIMFGPVALG---VKKSEAKKLAKFYLNKMGLDDSYLERSPfG 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 144 IGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI- 222
Cdd:PRK13631 177 LSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILk 256
|
250 260 270
....*....|....*....|....*....|....*....
gi 543000761 223 ----------ETMVKDATVSEDRIIKgmVGRDLVNRFPK 251
Cdd:PRK13631 257 tgtpyeiftdQHIINSTSIQVPRVIQ--VINDLIKKDPK 293
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
6-224 |
2.20e-13 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 68.71 E-value: 2.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGnvcsfKDIKDsekigia 85
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEVTEGEILFKG-----EDITD------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 iihqelalipyLSIgeniflgNERAKNGI-INWNT----THIKATEYLNRVGLKESSqtlikdigvGKQQLVEIAKALAK 160
Cdd:cd03217 69 -----------LPP-------EERARLGIfLAFQYppeiPGVKNADFLRYVNEGFSG---------GEKKRNEILQLLLL 121
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISH--KLNEVMKvADSITVLRDGATIET 224
Cdd:cd03217 122 EPDLAILDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHyqRLLDYIK-PDRVHVLYDGRIVKS 186
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
6-222 |
2.22e-13 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 68.73 E-value: 2.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNIT-----KLFPGVKA-LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGnvcsFKDIKDS 79
Cdd:cd03213 4 LSFRNLTvtvksSPSKSGKQlLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGVSGEVLING----RPLDKRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGIAIIHQELALIPYLSIGENIflgnerakngiinWNTTHIKateylnrvGLkeSSqtlikdigvGKQQLVEIAKALA 159
Cdd:cd03213 80 FRKIIGYVPQDDILHPTLTVRETL-------------MFAAKLR--------GL--SG---------GERKRVSIALELV 127
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 160 KDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKL-NEVMKVADSITVLRDGATI 222
Cdd:cd03213 128 SNPSLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVI 191
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
10-223 |
3.52e-13 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 69.69 E-value: 3.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 10 NITKLFPGVK---ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGNVCSF-KDIKDSEKIG-- 83
Cdd:PRK14246 12 NISRLYLYINdkaILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEI--YDSKIKVDGKVLYFgKDIFQIDAIKlr 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 --IAIIHQELALIPYLSIGENIflGNERAKNGIINWNTTHIKATEYLNRVGL-KESSQTL---IKDIGVGKQQLVEIAKA 157
Cdd:PRK14246 90 keVGMVFQQPNPFPHLSIYDNI--AYPLKSHGIKEKREIKKIVEECLRKVGLwKEVYDRLnspASQLSGGQQQRLTIARA 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 158 LAKDVKLLILDEPTAALNEEDSDNLLELILELKKHgITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK14246 168 LALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELVE 232
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
8-222 |
3.93e-13 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 69.43 E-value: 3.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 8 MRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEKiGIAII 87
Cdd:PRK10575 14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQP--PSEGEILLDAQPLESWSSKAFAR-KVAYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 88 HQELALIPYLSIGENIFLGNERAKNGIINWNTT-HIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:PRK10575 91 PQQLPAAEGMTVRELVAIGRYPWHGALGRFGAAdREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 167 LDEPTAALN-EEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK10575 171 LDEPTSALDiAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
281-484 |
5.72e-13 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 68.86 E-value: 5.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 281 NVNLKVHRGEVVGISGLMGSGRTELAMSVFG---------RAYGKHITG----KVKKDGKELLLKNVR-----QAIENGL 342
Cdd:PRK11300 23 NVNLEVREQEIVSLIGPNGAGKTTVFNCLTGfykptggtiLLRGQHIEGlpghQIARMGVVRTFQHVRlfremTVIENLL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 343 ayVTEDRKtaglvlidnIKKNIsLAKLGKLSKNQViDENKEIQVAEELRRKLNIKSSSILQkTGNLSGGNQQKVVLSKWI 422
Cdd:PRK11300 103 --VAQHQQ---------LKTGL-FSGLLKTPAFRR-AESEALDRAATWLERVGLLEHANRQ-AGNLAYGQQRRLEIARCM 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:PRK11300 169 VTQPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGT 231
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
2-223 |
5.78e-13 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 70.87 E-value: 5.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITKLFPG-----------VKALDNVNLKVKSGEVHALVGENGAGKSTL-MSVLSGIypygSYSGDIIFEGn 69
Cdd:COG4172 272 APPLLEARDLKVWFPIkrglfrrtvghVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLI----PSEGEIRFDG- 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 70 vcsfKDI--KDSEKI-----GIAIIHQElaliPY------LSIGENIFLG----------NERAKngiinwntthiKATE 126
Cdd:COG4172 347 ----QDLdgLSRRALrplrrRMQVVFQD----PFgslsprMTVGQIIAEGlrvhgpglsaAERRA-----------RVAE 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 127 YLNRVGLKES---------SqtlikdiGvGKQQLVEIAKALAKDVKLLILDEPTAAL---------------NEEdsdnl 182
Cdd:COG4172 408 ALEEVGLDPAarhryphefS-------G-GQRQRIAIARALILEPKLLVLDEPTSALdvsvqaqildllrdlQRE----- 474
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 543000761 183 lelilelkkHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:COG4172 475 ---------HGLAYLFISHDLAVVRALAHRVMVMKDGKVVE 506
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
19-262 |
5.81e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 69.38 E-value: 5.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYS---GDIIFEgNVCSFKDIKD-SEKIGIAIIHQELALI 94
Cdd:PRK13643 20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKvtvGDIVVS-STSKQKEIKPvRKKVGVVFQFPESQLF 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 PYlSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGL-KESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAA 173
Cdd:PRK13643 99 EE-TVLKDVAFG---PQNFGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 174 LNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATVSEDRIIKGM-VGRDLVNRFPKR 252
Cdd:PRK13643 175 LDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEVDFLKAHeLGVPKATHFADQ 254
|
250
....*....|
gi 543000761 253 EAKIGEIYFE 262
Cdd:PRK13643 255 LQKTGAVTFE 264
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
289-499 |
6.15e-13 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 71.06 E-value: 6.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 289 GEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKKDGKELLLKNVRQAienglAYVTEDRKTAGLVLIDNIKKNISLAK 368
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAGRIQGNNFTGTILANNRKPTKQILKRT-----GFVTQDDILYPHLTVRETLVFCSLLR 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 369 LGK-LSKNQvidenkEIQVAEELRRKLNiksssiLQKTGN----------LSGGNQQKVVLSKWIFTDPEVLILDEPTRG 437
Cdd:PLN03211 169 LPKsLTKQE------KILVAESVISELG------LTKCENtiignsfirgISGGERKRVSIAHEMLINPSLLILDEPTSG 236
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 438 IDVGAKYEIYTIINKLAEEGKSIII-ISSELPEILGMCDRIYVMNEGR--IVGELDQKDASQESI 499
Cdd:PLN03211 237 LDATAAYRLVLTLGSLAQKGKTIVTsMHQPSSRVYQMFDSVLVLSEGRclFFGKGSDAMAYFESV 301
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
273-486 |
6.15e-13 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 68.51 E-value: 6.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKKDGKELLLKNvrqaienglayvTEDRKTA 352
Cdd:CHL00131 17 VNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAYKILEGDILFKGESILDLE------------PEERAHL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GLVL-------IDNIKkNISLAKLGKLS--KNQVIDENKEIQVAEELRRKLNI--KSSSILQKTGN--LSGGNQQKVVLS 419
Cdd:CHL00131 85 GIFLafqypieIPGVS-NADFLRLAYNSkrKFQGLPELDPLEFLEIINEKLKLvgMDPSFLSRNVNegFSGGEKKRNEIL 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 420 KWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIIsSELPEILGMC--DRIYVMNEGRIV 486
Cdd:CHL00131 164 QMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILI-THYQRLLDYIkpDYVHVMQNGKII 231
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-223 |
6.17e-13 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 69.27 E-value: 6.17e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVK--ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKD 78
Cdd:PRK13635 1 MKEEIIRVEHISFRYPDAAtyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLL--PEAGTITVGGMVLSEETVWD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 -SEKIGIaiIHQElaliPylsigENIFLGNERA--------KNGI--------INWNTTHIKATEYLNRVGLKESSqtli 141
Cdd:PRK13635 79 vRRQVGM--VFQN----P-----DNQFVGATVQddvafgleNIGVpreemverVDQALRQVGMEDFLNREPHRLSG---- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 142 kdigvGKQQLVEIAKALAKDVKLLILDEPTAALN----EEDSDNLLELILELkkhGITSIIISHKLNEVMKvADSITVLR 217
Cdd:PRK13635 144 -----GQKQRVAIAGVLALQPDIIILDEATSMLDprgrREVLETVRQLKEQK---GITVLSITHDLDEAAQ-ADRVIVMN 214
|
....*.
gi 543000761 218 DGATIE 223
Cdd:PRK13635 215 KGEILE 220
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
404-488 |
8.31e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 69.06 E-value: 8.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 404 KTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:PRK13537 135 KVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEG 214
|
....*
gi 543000761 484 RIVGE 488
Cdd:PRK13537 215 RKIAE 219
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1-284 |
8.73e-13 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 69.67 E-value: 8.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILemRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNvcSFKDIKDSE 80
Cdd:PRK11000 1 MASVTL--RNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDIT--SGDLFIGEK--RMNDVPPAE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KiGIAIIHQELALIPYLSIGENIFLGNERAKngiinwntthIKATEYLNRVglKESSQTL---------IKDIGVGKQQL 151
Cdd:PRK11000 75 R-GVGMVFQSYALYPHLSVAENMSFGLKLAG----------AKKEEINQRV--NQVAEVLqlahlldrkPKALSGGQRQR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 152 VEIAKALAKDVKLLILDEP----TAALNEEdsdnllELILELKKH---GITSIIISHKLNEVMKVADSITVLrDGATIET 224
Cdd:PRK11000 142 VAIGRTLVAEPSVFLLDEPlsnlDAALRVQ------MRIEISRLHkrlGRTMIYVTHDQVEAMTLADKIVVL-DAGRVAQ 214
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 225 MVKDATV---SEDRIIKGMVGRDLVNRFPKR--EAKIGEIYFEI-NDWNVFDPvVDGKKVIKNVNL 284
Cdd:PRK11000 215 VGKPLELyhyPANRFVAGFIGSPKMNFLPVKvtATAIEQVQVELpNRQQVWLP-VEGRGVQVGANM 279
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
3-222 |
1.04e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 68.22 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 3 EFILEMRNITKLFP-GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKD-SE 80
Cdd:PRK13647 2 DNIIEVEDLHFRYKdGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYL--PQRGRVKVMGREVNAENEKWvRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGI-----------AIIHQELALIPylsigENIFLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQ 149
Cdd:PRK13647 80 KVGLvfqdpddqvfsSTVWDDVAFGP-----VNMGLDKDEVER----------RVEEALKAVRMWDFRDKPPYHLSYGQK 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 150 QLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13647 145 KRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVL 217
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
5-233 |
1.13e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 68.29 E-value: 1.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPG-VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKDSEK-I 82
Cdd:PRK13652 3 LIETRDLCYSYSGsKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILK--PTSGSVLIRGEPITKENIREVRKfV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIAI-----------IHQELALIPYlsigeNIFLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQL 151
Cdd:PRK13652 81 GLVFqnpddqifsptVEQDIAFGPI-----NLGLDEETVAH----------RVSSALHMLGLEELRDRVPHHLSGGEKKR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 152 VEIAKALAKDVKLLILDEPTAALNEEDSDNLLE-LILELKKHGITSIIISHKLNEVMKVADSITVLRDGatieTMVKDAT 230
Cdd:PRK13652 146 VAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDfLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKG----RIVAYGT 221
|
...
gi 543000761 231 VSE 233
Cdd:PRK13652 222 VEE 224
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
18-219 |
1.34e-12 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 67.17 E-value: 1.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSFkdikdsekIGIAIihqelALIPYL 97
Cdd:cd03220 35 FWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPD--SGTVTVRGRVSSL--------LGLGG-----GFNPEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 98 SIGENIFLgnerakNGII-NWNTTHIKatEYLNRV----GLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTA 172
Cdd:cd03220 100 TGRENIYL------NGRLlGLSRKEID--EKIDEIiefsELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLA 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 543000761 173 ALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03220 172 VGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKG 218
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
6-223 |
1.37e-12 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 69.85 E-value: 1.37e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG--VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSgiYPYGSYSGDIIFEGnvcsfKDIKD-SEKI 82
Cdd:PRK11160 339 LTLNNVSFTYPDqpQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLT--RAWDPQQGEILLNG-----QPIADySEAA 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 ---GIAIIHQElaliPYL---SIGENIFLGNERAkngiinwntTHIKATEYLNRVGLK---ESSQTLIKDIGVGKQQL-- 151
Cdd:PRK11160 412 lrqAISVVSQR----VHLfsaTLRDNLLLAAPNA---------SDEALIEVLQQVGLEkllEDDKGLNAWLGEGGRQLsg 478
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 152 -----VEIAKALAKDVKLLILDEPTAALneeDSDNLLELILELKKH--GITSIIISHKLNEVMKVaDSITVLRDGATIE 223
Cdd:PRK11160 479 geqrrLGIARALLHDAPLLLLDEPTEGL---DAETERQILELLAEHaqNKTVLMITHRLTGLEQF-DRICVMDNGQIIE 553
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
20-222 |
1.74e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 67.71 E-value: 1.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKD-SEKIGIAIIHQELALIPyLS 98
Cdd:PRK13632 24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLK--PQSGEIKIDGITISKENLKEiRKKIGIIFQNPDNQFIG-AT 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 99 IGENIFLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEED 178
Cdd:PRK13632 101 VEDDIAFGLE---NKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKG 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 543000761 179 SDNLLELILELKKHGITSII-ISHKLNEVMKvADSITVLRDGATI 222
Cdd:PRK13632 178 KREIKKIMVDLRKTRKKTLIsITHDMDEAIL-ADKVIVFSEGKLI 221
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
277-485 |
2.33e-12 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 66.65 E-value: 2.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRtelamSVFGRAygkhITGKVKKDGKELLLKNvrQAIENGLAYVTEDRKTAGLVL 356
Cdd:PRK09493 15 QVLHNIDLNIDQGEVVVIIGPSGSGK-----STLLRC----INKLEEITSGDLIVDG--LKVNDPKVDERLIRQEAGMVF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 -----------IDNIKknislakLGKLsknQVIDENKEiqVAEELRRKLniksssiLQKTG----------NLSGGNQQK 415
Cdd:PRK09493 84 qqfylfphltaLENVM-------FGPL---RVRGASKE--EAEKQAREL-------LAKVGlaerahhypsELSGGQQQR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 416 VVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK09493 145 VAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRI 214
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
276-486 |
2.42e-12 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 69.31 E-value: 2.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSV--FGRAYGKHITGKVKKDGKELLLKNVRQAIenglAYVTEDRKTAG 353
Cdd:TIGR00955 38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTL-MNAlaFRSPKGVKGSGSVLLNGMPIDAKEMRAIS----AYVQQDDLFIP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLAKLGK-LSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGnLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:TIGR00955 113 TLTVREHLMFQAHLRMPRrVTKKEKRERVDEVLQALGLRKCANTRIGVPGRVKG-LSGGERKRLAFASELLTDPPLLFCD 191
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKSIIII----SSELPEILgmcDRIYVMNEGRIV 486
Cdd:TIGR00955 192 EPTSGLDSFMAYSVVQVLKGLAQKGKTIICTihqpSSELFELF---DKIILMAEGRVA 246
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
276-488 |
2.50e-12 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 65.41 E-value: 2.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLknvrqaieNGlayvtedrktaglV 355
Cdd:cd03247 15 QQVLKNLSLELKQGEKIALLGRSGSGKSTLL---------QLLTGDLKPQQGEITL--------DG-------------V 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISlaklgklsknqvidenKEIQVaeeLRRKLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:cd03247 65 PVSDLEKALS----------------SLISV---LNQRPYLFDTTLRNNLGrRFSGGERQRLALARILLQDAPIVLLDEP 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEEgKSIIIISSELPEILGMcDRIYVMNEGRIVGE 488
Cdd:cd03247 126 TVGLDPITERQLLSLIFEVLKD-KTLIWITHHLTGIEHM-DKILFLENGKIIMQ 177
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
277-497 |
3.26e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 67.07 E-value: 3.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKV-----KKDGKELLLKNVRQAIenGLAYVTEDRKt 351
Cdd:PRK13643 20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVgdivvSSTSKQKEIKPVRKKV--GVVFQFPESQ- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 aglVLIDNIKKNISLAklgklSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:PRK13643 97 ---LFEETVLKDVAFG-----PQNFGIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVL 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKDASQE 497
Cdd:PRK13643 169 DEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-223 |
3.38e-12 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 66.34 E-value: 3.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVL---SGIYPYGSYSGDIIFEG-NVCSFK-D 75
Cdd:PRK14239 1 MTEPILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrmNDLNPEVTITGSIVYNGhNIYSPRtD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 76 IKDSEKiGIAIIHQELALIPyLSIGENIFLGnERAKNgiinwntthIKATEYLNRV---GLKESS-QTLIKD------IG 145
Cdd:PRK14239 81 TVDLRK-EIGMVFQQPNPFP-MSIYENVVYG-LRLKG---------IKDKQVLDEAvekSLKGASiWDEVKDrlhdsaLG 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 146 V--GKQQLVEIAKALAKDVKLLILDEPTAALnEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK14239 149 LsgGQQQRVCIARVLATSPKIILLDEPTSAL-DPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIE 227
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
3-223 |
3.93e-12 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 66.74 E-value: 3.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 3 EFILEMRNITKLF---------PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSF 73
Cdd:PRK15112 2 ETLLEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIE--PTSGELLIDDHPLHF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 74 KDIK-DSEKIGIAIIHQELALIPYLSIGE--------NIFL-GNERAKngiinwnttHIKATeyLNRVGLKESSQTLIKD 143
Cdd:PRK15112 80 GDYSyRSQRIRMIFQDPSTSLNPRQRISQildfplrlNTDLePEQREK---------QIIET--LRQVGLLPDHASYYPH 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 144 -IGVGKQQLVEIAKALAKDVKLLILDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGAT 221
Cdd:PRK15112 149 mLAPGQKQRLGLARALILRPKVIIADEALASLDMSmRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEV 228
|
..
gi 543000761 222 IE 223
Cdd:PRK15112 229 VE 230
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
21-174 |
4.12e-12 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 65.28 E-value: 4.12e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSEKIGIA--IIHQElALIPYLS 98
Cdd:PRK13539 18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLP--PAAGTIKLDG-----GDIDDPDVAEAChyLGHRN-AMKPALT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 99 IGENI-----FLGNERakngiinwntTHIKATeyLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAA 173
Cdd:PRK13539 90 VAENLefwaaFLGGEE----------LDIAAA--LEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAA 157
|
.
gi 543000761 174 L 174
Cdd:PRK13539 158 L 158
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1-229 |
4.78e-12 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 66.91 E-value: 4.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITK-------LFPG---VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnv 70
Cdd:PRK11308 1 SQQPLLQAIDLKKhypvkrgLFKPerlVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIET--PTGGELYYQG-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 71 csfKDIKDSEKIGIAIIHQELALI---PYLSIgeniflgNERAKNG-------IINWNTTHI----KATEYLNRVGLK-E 135
Cdd:PRK11308 77 ---QDLLKADPEAQKLLRQKIQIVfqnPYGSL-------NPRKKVGqileeplLINTSLSAAerreKALAMMAKVGLRpE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 136 SSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALN---------------EEdsdnllelilelkkHGITSIIIS 200
Cdd:PRK11308 147 HYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDvsvqaqvlnlmmdlqQE--------------LGLSYVFIS 212
|
250 260
....*....|....*....|....*....
gi 543000761 201 HKLNEVMKVADSITVLRDGATIETMVKDA 229
Cdd:PRK11308 213 HDLSVVEHIADEVMVMYLGRCVEKGTKEQ 241
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
277-486 |
5.24e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 66.57 E-value: 5.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRT---ELAMSVFGRAYGKHITGKVKKDGKellLKNVRQaienglayVTEDRKTAG 353
Cdd:PRK13645 25 KALNNTSLTFKKNKVTCVIGTTGSGKStmiQLTNGLIISETGQTIVGDYAIPAN---LKKIKE--------VKRLRKEIG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLI--------DNIKKNISLAKLGklsknqvIDENKE--IQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIF 423
Cdd:PRK13645 94 LVFQfpeyqlfqETIEKDIAFGPVN-------LGENKQeaYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 424 TDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK13645 167 MDGNTLVLDEPTGGLDPKGEEDFINLFERLnKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVI 230
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
403-486 |
5.70e-12 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 64.91 E-value: 5.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 403 QKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgkSIIIISSELPE-ILGMCDRIYVMN 481
Cdd:cd03264 126 KKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGED--RIVILSTHIVEdVESLCNQVAVLN 203
|
....*
gi 543000761 482 EGRIV 486
Cdd:cd03264 204 KGKLV 208
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
404-488 |
6.59e-12 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 66.78 E-value: 6.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 404 KTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:PRK13536 169 RVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAG 248
|
....*
gi 543000761 484 RIVGE 488
Cdd:PRK13536 249 RKIAE 253
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
277-485 |
6.64e-12 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 65.76 E-value: 6.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRT-------------ELAMSVfgraYGKHITGKVKKDGK-ELLLKNVRQAIENGL 342
Cdd:PRK10619 19 EVLKGVSLQANAGDVISIIGSSGSGKStflrcinflekpsEGSIVV----NGQTINLVRDKDGQlKVADKNQLRLLRTRL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 343 AYVTEDRKT-AGLVLIDNIKKnISLAKLGkLSKNQVIDEnkeiqvAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKW 421
Cdd:PRK10619 95 TMVFQHFNLwSHMTVLENVME-APIQVLG-LSKQEARER------AVKYLAKVGIDERAQGKYPVHLSGGQQQRVSIARA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK10619 167 LAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
279-483 |
6.88e-12 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 65.18 E-value: 6.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKElllknvrqaienglayVTE---DRktagLV 355
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTS--GGVILEGKQ----------------ITEpgpDR----MV 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDN--------IKKNISLA------KLGKLSKNQVIDENKEIQVAEELRRKlniksssilqKTGNLSGGNQQKVVLSKW 421
Cdd:TIGR01184 59 VFQNysllpwltVRENIALAvdrvlpDLSKSERRAIVEEHIALVGLTEAADK----------RPGQLSGGMKQRVAIARA 128
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:TIGR01184 129 LSIRPKVLLLDEPFGALDALTRGNLQEELMQIWEEhRVTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
274-486 |
9.70e-12 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 65.29 E-value: 9.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKkdgkeLLLKNVRQAI-ENGLAYV--TEDRK 350
Cdd:PRK15056 18 NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMG--FVRLASGKIS-----ILGQPTRQALqKNLVAYVpqSEEVD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 TAGLVLIDNIkknISLAKLGKLSKNQVIDENKEIQVAEELRR--KLNIKSSSIlqktGNLSGGNQQKVVLSKWIFTDPEV 428
Cdd:PRK15056 91 WSFPVLVEDV---VMMGRYGHMGWLRRAKKRDRQIVTAALARvdMVEFRHRQI----GELSGGQKKRVFLARAIAQQGQV 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 429 LILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIyVMNEGRIV 486
Cdd:PRK15056 164 ILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYT-VMVKGTVL 220
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
20-224 |
9.71e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 65.54 E-value: 9.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSFKDIKDSEKiGIAIIHQElalipylsi 99
Cdd:PRK13648 24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKS--GEIFYNNQAITDDNFEKLRK-HIGIVFQN--------- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 GENIFLGNERA-------KNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTA 172
Cdd:PRK13648 92 PDNQFVGSIVKydvafglENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATS 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 173 ALNEEDSDN-LLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIET 224
Cdd:PRK13648 172 MLDPDARQNlLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKE 223
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
19-224 |
1.13e-11 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 65.92 E-value: 1.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPY-GSYSGD-IIFEGNvcSFKDIKDSEK---IG--IAIIHQE- 90
Cdd:PRK11022 21 RAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYpGRVMAEkLEFNGQ--DLQRISEKERrnlVGaeVAMIFQDp 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 91 -LALIPYLSIGENIFLGNERAKNGiiNWNTTHIKATEYLNRVGLKESSQTL---IKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:PRK11022 99 mTSLNPCYTVGFQIMEAIKVHQGG--NKKTRRQRAIDLLNQVGIPDPASRLdvyPHQLSGGMSQRVMIAMAIACRPKLLI 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 167 LDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:PRK11022 177 ADEPTTALDVTiQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVET 235
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
277-486 |
1.22e-11 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 64.48 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYGKhITGKVKKDG---KELLLKNVRQAIenglAYVTEDRktag 353
Cdd:cd03249 17 PILKGLSLTIPPGKTVALVGSSGCGKSTV-VSLLERFYDP-TSGEILLDGvdiRDLNLRWLRSQI----GLVSQEP---- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 lVLIDN-IKKNIslaklgKLSKNQVIDEnkeiqVAEELRRKLNIKSSSIL----------QKTGNLSGGNQQKVVLSKWI 422
Cdd:cd03249 87 -VLFDGtIAENI------RYGKPDATDE-----EVEEAAKKANIHDFIMSlpdgydtlvgERGSQLSGGQKQRIAIARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:cd03249 155 LRNPKILLLDEATSALDAESEKLVQEALDRAM-KGRTTIVIAHRLSTIRN-ADLIAVLQNGQVV 216
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
274-486 |
1.41e-11 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 64.24 E-value: 1.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRT---------ElamsvfgraygKHITGKVKKDGKELLL--KNVRQAiengl 342
Cdd:COG1126 12 GDLEVLKGISLDVEKGEVVVIIGPSGSGKStllrcinllE-----------EPDSGTITVDGEDLTDskKDINKL----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 343 ayvtedRKTAGLV-----LIDN--IKKNISLA--KLGKLSKNQvidenkeiqvAEELRRKLniksssiLQKTG------- 406
Cdd:COG1126 76 ------RRKVGMVfqqfnLFPHltVLENVTLApiKVKKMSKAE----------AEERAMEL-------LERVGladkada 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 ---NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGID---VGakyEIYTIINKLAEEGKSIIIISSElpeilgM------C 474
Cdd:COG1126 133 ypaQLSGGQQQRVAIARALAMEPKVMLFDEPTSALDpelVG---EVLDVMRDLAKEGMTMVVVTHE------MgfarevA 203
|
250
....*....|..
gi 543000761 475 DRIYVMNEGRIV 486
Cdd:COG1126 204 DRVVFMDGGRIV 215
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
21-170 |
1.51e-11 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 66.58 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsYSGDIIF----EGNVCSFKDIKdsEKIGI--AIIHQELALi 94
Cdd:PRK10938 276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQG-YSNDLTLfgrrRGSGETIWDIK--KHIGYvsSSLHLDYRV- 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 pylsigeniflgNERAKNGIINW------------NTTHIKATEYLNRVGL-KESSQTLIKDIGVGKQQLVEIAKALAKD 161
Cdd:PRK10938 352 ------------STSVRNVILSGffdsigiyqavsDRQQKLAQQWLDILGIdKRTADAPFHSLSWGQQRLALIVRALVKH 419
|
....*....
gi 543000761 162 VKLLILDEP 170
Cdd:PRK10938 420 PTLLILDEP 428
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
18-72 |
1.67e-11 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 64.33 E-value: 1.67e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 18 VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCS 72
Cdd:COG1134 39 FWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILE--PTSGRVEVNGRVSA 91
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
21-222 |
1.83e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 64.64 E-value: 1.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCsfkdikDSEKIGIAIIHQELAL------- 93
Cdd:PRK13638 17 LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLR--PQKGAVLWQGKPL------DYSKRGLLALRQQVATvfqdpeq 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 -IPYLSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTA 172
Cdd:PRK13638 89 qIFYTDIDSDIAFS---LRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTA 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 173 ALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13638 166 GLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQIL 215
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
278-486 |
1.83e-11 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 66.31 E-value: 1.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgRAygkhIT-------GKVKKDGKELLLKNvRQAIENGLAYVTEDrk 350
Cdd:COG4618 347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLA-----RL----LVgvwpptaGSVRLDGADLSQWD-REELGRHIGYLPQD-- 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 tagLVLID-NIKKNIslAKLGKLSKNQVIDENKEIQVaEELrrklniksssILQ-----KT------GNLSGGNQQKVVL 418
Cdd:COG4618 415 ---VELFDgTIAENI--ARFGDADPEKVVAAAKLAGV-HEM----------ILRlpdgyDTrigeggARLSGGQRQRIGL 478
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIIsSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG4618 479 ARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVI-THRPSLLAAVDKLLVLRDGRVQ 545
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
276-488 |
2.15e-11 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 64.32 E-value: 2.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKEL--LLKNVRQAIENGLAYVTED----- 348
Cdd:PRK10419 25 QTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQ--GNVSWRGEPLakLNRAQRKAFRRDIQMVFQDsisav 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 --RKTAGLVLIDNIKKNISLAKLGKLSKnqvidenkeiqvAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK10419 103 npRKTVREIIREPLRHLLSLDKAERLAR------------ASEMLRAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEP 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK10419 171 KLLILDEAVSNLDLVLQAGVIRLLKKLQQQfGTACLFITHDLRLVERFCQRVMVMDNGQIVET 233
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
21-219 |
2.60e-11 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 63.88 E-value: 2.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDSEKIGIAiihQELALIP-YLSI 99
Cdd:PRK11231 18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLT--PQSGTVFLGD-----KPISMLSSRQLA---RRLALLPqHHLT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 GENIFLgNERAKNGIINWNT--------THIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPT 171
Cdd:PRK11231 88 PEGITV-RELVAYGRSPWLSlwgrlsaeDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPT 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 543000761 172 AALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK11231 167 TYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANG 214
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
21-177 |
2.71e-11 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 63.44 E-value: 2.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIifegnvcsfkDIKDSEkigiaiIHQELALIpylsig 100
Cdd:COG2401 46 LRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCV----------DVPDNQ------FGREASLI------ 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 ENIflgnerAKNGIINwntthiKATEYLNRVGLkeSSQTLI----KDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNE 176
Cdd:COG2401 104 DAI------GRKGDFK------DAVELLNAVGL--SDAVLWlrrfKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDR 169
|
.
gi 543000761 177 E 177
Cdd:COG2401 170 Q 170
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
276-503 |
2.80e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 64.34 E-value: 2.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNVRQAIENGLAYVtedRKTAGLV 355
Cdd:PRK13633 23 KLALDDVNLEVKKGEFLVILGRNGSGKSTIA---------KHMNALLIPSEGKVYVDGLDTSDEENLWDI---RNKAGMV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDnikknislaklgklSKNQVIDENKEIQVA----------EELRRKLNikssSILQKTGN----------LSGGNQQK 415
Cdd:PRK13633 91 FQN--------------PDNQIVATIVEEDVAfgpenlgippEEIRERVD----ESLKKVGMyeyrrhaphlLSGGQKQR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 416 VVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILgMCDRIYVMNEGRIVGELDQKDA 494
Cdd:PRK13633 153 VAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELnKKYGITIILITHYMEEAV-EADRIIVMDSGKVVMEGTPKEI 231
|
250
....*....|
gi 543000761 495 -SQESIMKCI 503
Cdd:PRK13633 232 fKEVEMMKKI 241
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
279-488 |
2.91e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 63.96 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNV---RQAIenGLAYVTEDRKTAGLV 355
Cdd:PRK13642 23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDG--LFEEFEGKVKIDGELLTAENVwnlRRKI--GMVFQNPDNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNIslaklgklsKNQVIDENKEIQVAEELRRKLNIKSSSIlQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPT 435
Cdd:PRK13642 99 VEDDVAFGM---------ENQGIPREEMIKRVDEALLAVNMLDFKT-REPARLSGGQKQRVAVAGIIALRPEIIILDEST 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 436 RGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEIlGMCDRIYVMNEGRIVGE 488
Cdd:PRK13642 169 SMLDPTGRQEIMRVIHEIKEKYQlTVLSITHDLDEA-ASSDRILVMKAGEIIKE 221
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
277-486 |
3.09e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 64.49 E-value: 3.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELA-------MSVFGRAYGKHITGKVKKDGKELLLKNVRQAIENglayVTEDR 349
Cdd:PRK13631 40 VALNNISYTFEKNKIYFIIGNSGSGKSTLVthfngliKSKYGTIQVGDIYIGDKKNNHELITNPYSKKIKN----FKELR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 KTAGLVL--------IDNIKKNISLAKLgklskNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKW 421
Cdd:PRK13631 116 RRVSMVFqfpeyqlfKDTIEKDIMFGPV-----ALGVKKSEAKKLAKFYLNKMGLDDSYLERSPFGLSGGQKRRVAIAGI 190
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK13631 191 LAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKIL 255
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1-219 |
3.19e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 64.05 E-value: 3.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVK--ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-PYGSYSGDIIFEGNVCSFKDIK 77
Cdd:PRK13640 1 MKDNIVEFKHVSFTYPDSKkpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlPDDNPNSKITVDGITLTAKTVW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 78 D-SEKIGIAIIHQELALIPyLSIGENIFLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAK 156
Cdd:PRK13640 81 DiREKVGIVFQNPDNQFVG-ATVGDDVAFGLE---NRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAG 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 157 ALAKDVKLLILDEPTAALNEEDSDNL-LELILELKKHGITSIIISHKLNEVmKVADSITVLRDG 219
Cdd:PRK13640 157 ILAVEPKIIILDESTSMLDPAGKEQIlKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDG 219
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
279-488 |
3.32e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 63.88 E-value: 3.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKhiTGKVKKDGKELLLKNV---RQAIenGLAYVTEDRKTAGLV 355
Cdd:PRK13635 23 LKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPE--AGTITVGGMVLSEETVwdvRRQV--GMVFQNPDNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNIslaklgklsKNQVIDENKEIQVAEELRRKLNIKSSsILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPT 435
Cdd:PRK13635 99 VQDDVAFGL---------ENIGVPREEMVERVDQALRQVGMEDF-LNREPHRLSGGQKQRVAIAGVLALQPDIIILDEAT 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 436 RGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILgMCDRIYVMNEGRIVGE 488
Cdd:PRK13635 169 SMLDPRGRREVLETVRQLKEQKGiTVLSITHDLDEAA-QADRVIVMNKGEILEE 221
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
281-497 |
3.49e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 64.00 E-value: 3.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 281 NVNLKVHRGEVVGISGLMGSGRTELaMSVFGrayGKHI--TGKVKKDGKELLLKNVRQAIENglayvteDRKTAGLVL-- 356
Cdd:PRK13649 25 DVNLTIEDGSYTAFIGHTGSGKSTI-MQLLN---GLHVptQGSVRVDDTLITSTSKNKDIKQ-------IRKKVGLVFqf 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 ------IDNIKKNISLAklgklSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLI 430
Cdd:PRK13649 94 pesqlfEETVLKDVAFG-----PQNFGVSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILV 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 431 LDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKDASQE 497
Cdd:PRK13649 169 LDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQD 235
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
277-486 |
3.92e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 63.39 E-value: 3.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRA---YGK-HITGKVKKDGKELLLKNVrqaienglayvTEDRKTA 352
Cdd:PRK14247 17 EVLDGVNLEIPDNTITALMGPSGSGKSTL-LRVFNRLielYPEaRVSGEVYLDGQDIFKMDV-----------IELRRRV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GLVL-IDN------IKKNISLA-KLGKLSKNQ------VIDENKEIQVAEELRRKLNIKSssilqktGNLSGGNQQKVVL 418
Cdd:PRK14247 85 QMVFqIPNpipnlsIFENVALGlKLNRLVKSKkelqerVRWALEKAQLWDEVKDRLDAPA-------GKLSGGQQQRLCI 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK14247 158 ARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIV 224
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
274-485 |
4.03e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 63.52 E-value: 4.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRtelamSVFGRAYGK--HITGKVKKDGK-ELLLKNVRQAIENglayVTEDRK 350
Cdd:PRK14258 18 DTQKILEGVSMEIYQSKVTAIIGPSGCGK-----STFLKCLNRmnELESEVRVEGRvEFFNQNIYERRVN----LNRLRR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 TAGLV----------LIDNIKKNISLAKL-GKLSKNQVIDEN-KEIQVAEELRRKLNiKSSSilqktgNLSGGNQQKVVL 418
Cdd:PRK14258 89 QVSMVhpkpnlfpmsVYDNVAYGVKIVGWrPKLEIDDIVESAlKDADLWDEIKHKIH-KSAL------DLSGGQQQRLCI 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILGMCD--RIYVMNEGRI 485
Cdd:PRK14258 162 ARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSElTMVIVSHNLHQVSRLSDftAFFKGNENRI 231
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-211 |
4.19e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 63.52 E-value: 4.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFI--LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypyGSYSGDIIFEGNVCSFKDIKD 78
Cdd:PRK14258 1 MSKLIpaIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRM---NELESEVRVEGRVEFFNQNIY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SEKIGI-------AIIHQELALIPyLSIGENIFLGNErakngIINWN---------TTHIKATEYLNRVGLKESSQTLik 142
Cdd:PRK14258 78 ERRVNLnrlrrqvSMVHPKPNLFP-MSVYDNVAYGVK-----IVGWRpkleiddivESALKDADLWDEIKHKIHKSAL-- 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 143 DIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHG-ITSIIISHKLNEVMKVAD 211
Cdd:PRK14258 150 DLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSeLTMVIVSHNLHQVSRLSD 219
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
276-486 |
4.25e-11 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 63.12 E-value: 4.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLknvrqaiengLAYVTEDRKtaglv 355
Cdd:cd03267 34 VEALKGISFTIEKGEIVGFIGPNGAGKTTTL---------KILSGLLQPTSGEVRV----------AGLVPWKRR----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 liDNIKKNISLAkLGklSKNQ------VIDE---NKEIQVAEELRRKLNIKSSSILQKTG--------NLSGGNQQKVVL 418
Cdd:cd03267 90 --KKFLRRIGVV-FG--QKTQlwwdlpVIDSfylLAAIYDLPPARFKKRLDELSELLDLEelldtpvrQLSLGQRMRAEI 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03267 165 AAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYnRERGTTVLLTSHYMKDIEALARRVLVIDKGRLL 233
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
276-486 |
4.28e-11 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 63.49 E-value: 4.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKEL-LLKNVRQAIENGLAYVTEDRKTAgl 354
Cdd:PRK13638 14 EPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQK--GAVLWQGKPLdYSKRGLLALRQQVATVFQDPEQQ-- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKKNI--SLAKLGkLSKNQV---IDENKEIQVAEELRRklniksssilQKTGNLSGGNQQKVVLSKWIFTDPEVL 429
Cdd:PRK13638 90 IFYTDIDSDIafSLRNLG-VPEAEItrrVDEALTLVDAQHFRH----------QPIQCLSHGQKKRVAIAGALVLQARYL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 430 ILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK13638 159 LLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQIL 215
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
268-490 |
4.28e-11 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 63.18 E-value: 4.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 268 VFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTEL--AMSVFGRAYGkhitGKVKKDGKELllknvrQAIENGLAYV 345
Cdd:COG1116 16 RFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLlrLIAGLEKPTS----GEVLVDGKPV------TGPGPDRGVV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 346 T-EDR----KTaglvlidnIKKNISLA-KLGKLSKnqviDENKEIqvAEELrrklniksssiLQKTG----------NLS 409
Cdd:COG1116 86 FqEPAllpwLT--------VLDNVALGlELRGVPK----AERRER--AREL-----------LELVGlagfedayphQLS 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 410 GGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNE--GRIV 486
Cdd:COG1116 141 GGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLwQETGKTVLFVTHDVDEAVFLADRVVVLSArpGRIV 220
|
....
gi 543000761 487 GELD 490
Cdd:COG1116 221 EEID 224
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
17-219 |
4.95e-11 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 62.58 E-value: 4.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 17 GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSfkDIKDSE----KIGIAIIHQELA 92
Cdd:PRK10908 14 GRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIER--PSAGKIWFSGHDIT--RLKNREvpflRRQIGMIFQDHH 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 93 LIPYLSIGENIflgnerAKNGIINWNTT---HIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDE 169
Cdd:PRK10908 90 LLMDRTVYDNV------AIPLIIAGASGddiRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADE 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 170 PTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK10908 164 PTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDG 213
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
25-219 |
5.00e-11 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 62.68 E-value: 5.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 25 NLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSfkdIKDSEKIGIAIIHQELALIPYLSIGENIF 104
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLT--PASGSLTLNGQDHT---TTPPSRRPVSMLFQENNLFSHLTVAQNIG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 105 LGnerAKNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALN--------- 175
Cdd:PRK10771 94 LG---LNPGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDpalrqemlt 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 543000761 176 --EEDSDNllelilelkkHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK10771 171 lvSQVCQE----------RQLTLLMVSHSLEDAARIAPRSLVVADG 206
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
273-486 |
5.05e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 63.14 E-value: 5.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYGKHiTGKVKKDGKELL-------LKNVRQAIENGLAYv 345
Cdd:PRK14246 20 INDKAILKDITIKIPNNSIFGIMGPSGSGKSTL-LKVLNRLIEIY-DSKIKVDGKVLYfgkdifqIDAIKLRKEVGMVF- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 346 TEDRKTAGLVLIDNIKKNIslaklgklsKNQVIDENKEIQ-VAEELRRKLNIKSS---SILQKTGNLSGGNQQKVVLSKW 421
Cdd:PRK14246 97 QQPNPFPHLSIYDNIAYPL---------KSHGIKEKREIKkIVEECLRKVGLWKEvydRLNSPASQLSGGQQQRLTIARA 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK14246 168 LALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELV 231
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
5-68 |
5.28e-11 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 63.12 E-value: 5.28e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEG 68
Cdd:CHL00131 7 ILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAYKILEGDILFKG 70
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
275-486 |
5.89e-11 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 65.15 E-value: 5.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKelLLKNV-RQAIENGLAYVTEDRktag 353
Cdd:TIGR01193 486 GSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARS--GEILLNGF--SLKDIdRHTLRQFINYLPQEP---- 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDE 433
Cdd:TIGR01193 558 YIFSGSILENLLLGAKENVSQDEIWAACEIAEIKDDIENMPLGYQTELSEEGSSISGGQKQRIALARALLTDSKVLILDE 637
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 434 PTRGIDVGAKYEIytIINKLAEEGKSIIIISSELpEILGMCDRIYVMNEGRIV 486
Cdd:TIGR01193 638 STSNLDTITEKKI--VNNLLNLQDKTIIFVAHRL-SVAKQSDKIIVLDHGKII 687
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
19-223 |
6.64e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 63.26 E-value: 6.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYP--YGSYSGDIIFEGNVCSFKDIKD-SEKIGIAIIHQELALIP 95
Cdd:PRK13646 21 QAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKptTGTVTVDDITITHKTKDKYIRPvRKRIGMVFQFPESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YlSIGENIFLGnerAKNGIINWNTTHIKATEYLNRVGLKES--SQTLIKDIGvGKQQLVEIAKALAKDVKLLILDEPTAA 173
Cdd:PRK13646 101 D-TVEREIIFG---PKNFKMNLDEVKNYAHRLLMDLGFSRDvmSQSPFQMSG-GQMRKIAIVSILAMNPDIIVLDEPTAG 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 543000761 174 LNEEDSDNLLE-LILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK13646 176 LDPQSKRQVMRlLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVS 226
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
275-462 |
7.13e-11 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 62.04 E-value: 7.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELllKNVRQaieNGLAYVtedRKTAGL 354
Cdd:cd03292 13 GTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEE--LPTSGTIRVNGQDV--SDLRG---RAIPYL---RRKIGV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLID-------NIKKNISLAKlgklsknQVIDEN-KEIQ--VAEELRR-KLNIKSSSILQKtgnLSGGNQQKVVLSKWIF 423
Cdd:cd03292 83 VFQDfrllpdrNVYENVAFAL-------EVTGVPpREIRkrVPAALELvGLSHKHRALPAE---LSGGEQQRVAIARAIV 152
|
170 180 190
....*....|....*....|....*....|....*....
gi 543000761 424 TDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIII 462
Cdd:cd03292 153 NSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVV 191
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
19-222 |
7.16e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 62.84 E-value: 7.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY--PYGSYSGDIIFEGNVCSFKDIKD-SEKIGIAIIHQELALIP 95
Cdd:PRK13649 21 RALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHvpTQGSVRVDDTLITSTSKNKDIKQiRKKVGLVFQFPESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YLSIGENIFlgneraknGIINWNTTHIKAT----EYLNRVGLKESsqtLIK----DIGVGKQQLVEIAKALAKDVKLLIL 167
Cdd:PRK13649 101 ETVLKDVAF--------GPQNFGVSQEEAEalarEKLALVGISES---LFEknpfELSGGQMRRVAIAGILAMEPKILVL 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 168 DEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13649 170 DEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLV 224
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
258-494 |
7.24e-11 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 63.57 E-value: 7.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 258 EIYFEINDWNVFDPVVDGK----------KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGK 327
Cdd:PRK15079 6 KVLLEVADLKVHFDIKDGKqwfwqppktlKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLV--KATDGEVAWLGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 328 ELL------LKNVRQAIE----NGLAYVTEdRKTAGLVLIDNIKknislAKLGKLSKNQVIDENKEIQVaeelrrKLNIK 397
Cdd:PRK15079 84 DLLgmkddeWRAVRSDIQmifqDPLASLNP-RMTIGEIIAEPLR-----TYHPKLSRQEVKDRVKAMML------KVGLL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 398 SSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDR 476
Cdd:PRK15079 152 PNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDR 231
|
250
....*....|....*...
gi 543000761 477 IYVMNEGRIVgELDQKDA 494
Cdd:PRK15079 232 VLVMYLGHAV-ELGTYDE 248
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
21-207 |
7.31e-11 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 64.97 E-value: 7.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCsfkdikdseKIGIAIIHQELALIPYLSI 99
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINE--SAEGEIIIDGlNIA---------KIGLHDLRFKITIIPQDPV 1370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 genIFLGNERAK--------NGIINW--NTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDE 169
Cdd:TIGR00957 1371 ---LFSGSLRMNldpfsqysDEEVWWalELAHLKTFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDE 1447
|
170 180 190
....*....|....*....|....*....|....*...
gi 543000761 170 PTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVM 207
Cdd:TIGR00957 1448 ATAAVDLE-TDNLIQSTIRTQFEDCTVLTIAHRLNTIM 1484
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
275-483 |
8.43e-11 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 62.95 E-value: 8.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKhiTGKVKKDGKelllknvrqaiengLAYVTEdrktAGL 354
Cdd:cd03291 49 GAPVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPS--EGKIKHSGR--------------ISFSSQ----FSW 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKKNIslakLGKLSKNQ-----VIdenKEIQVAEELrRKLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTDPEV 428
Cdd:cd03291 109 IMPGTIKENI----IFGVSYDEyryksVV---KACQLEEDI-TKFPEKDNTVLGEGGiTLSGGQRARISLARAVYKDADL 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 429 LILDEPTRGIDVGAKYEIY-TIINKLAEEgKSIIIISSELpEILGMCDRIYVMNEG 483
Cdd:cd03291 181 YLLDSPFGYLDVFTEKEIFeSCVCKLMAN-KTRILVTSKM-EHLKKADKILILHEG 234
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-222 |
8.82e-11 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 63.31 E-value: 8.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGnvCSFKDIKDSE 80
Cdd:PRK13536 37 MSTVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDA--GKITVLG--VPVPARARLA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPYLSIGENIFLGNErakngIINWNTTHIKAT--EYLNRVGLKESSQTLIKDIGVGKQQLVEIAKAL 158
Cdd:PRK13536 113 RARIGVVPQFDNLDLEFTVRENLLVFGR-----YFGMSTREIEAVipSLLEFARLESKADARVSDLSGGMKRRLTLARAL 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 159 AKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13536 188 INDPQLLILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKI 251
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
274-486 |
1.06e-10 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 61.61 E-value: 1.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgkHIT-GKVKKDGKelllkNVRQAIENGLAYVtedRKTA 352
Cdd:COG2884 13 GGREALSDVSLEIEKGEFVFLTGPSGAGKSTL-LKLLYGEE--RPTsGQVLVNGQ-----DLSRLKRREIPYL---RRRI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GLV-----LIDN--IKKNISLAklgklsknqvidenkeIQVAEELRRKLNIKSSSILQKTG----------NLSGGNQQK 415
Cdd:COG2884 82 GVVfqdfrLLPDrtVYENVALP----------------LRVTGKSRKEIRRRVREVLDLVGlsdkakalphELSGGEQQR 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 416 VVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG2884 146 VAIARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRLV 216
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
7-233 |
1.21e-10 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 62.02 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 7 EMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGnvcsfKDIKD--SEKIG- 83
Cdd:COG4604 3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPD--SGEVLVDG-----LDVATtpSRELAk 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 -IAIIHQELALIPYLSIGENIFLG-----------NERAkngIINwntthiKATEYLNrvgLKESSQTLIKDIGVGKQQL 151
Cdd:COG4604 76 rLAILRQENHINSRLTVRELVAFGrfpyskgrltaEDRE---IID------EAIAYLD---LEDLADRYLDELSGGQRQR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 152 VEIAKALAKDVKLLILDEPtaaLNEED--------------SDNllelilelkkHGITSIIISHKLNEVMKVADSITVLR 217
Cdd:COG4604 144 AFIAMVLAQDTDYVLLDEP---LNNLDmkhsvqmmkllrrlADE----------LGKTVVIVLHDINFASCYADHIVAMK 210
|
250
....*....|....*.
gi 543000761 218 DGAtietMVKDATVSE 233
Cdd:COG4604 211 DGR----VVAQGTPEE 222
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
274-480 |
1.23e-10 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 63.84 E-value: 1.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTEL--AMSVFGRAYGkhitGKVKKDGKELLLKNvRQAIENGLAYVTEdrkt 351
Cdd:TIGR02857 333 GRRPALRPVSFTVPPGERVALVGPSGAGKSTLlnLLLGFVDPTE----GSIAVNGVPLADAD-ADSWRDQIAWVPQ---- 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 AGLVLIDNIKKNISLAKLGklSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGN-LSGGNQQKVVLSKWIFTDPEVLI 430
Cdd:TIGR02857 404 HPFLFAGTIAENIRLARPD--ASDAEIREALERAGLDEFVAALPQGLDTPIGEGGAgLSGGQAQRLALARAFLRDAPLLL 481
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 431 LDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSElPEILGMCDRIYVM 480
Cdd:TIGR02857 482 LDEPTAHLDAETEAEVLEALRALA-QGRTVLLVTHR-LALAALADRIVVL 529
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
6-177 |
1.30e-10 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 60.84 E-value: 1.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSfkDIKDSEKIGIA 85
Cdd:TIGR01189 1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLR--PDSGEVRWNGTPLA--EQRDEPHENIL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENI-----FLGNERakngiinwNTTHikatEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:TIGR01189 77 YLGHLPGLKPELSALENLhfwaaIHGGAQ--------RTIE----DALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLS 144
|
170
....*....|....*..
gi 543000761 161 DVKLLILDEPTAALNEE 177
Cdd:TIGR01189 145 RRPLWILDEPTTALDKA 161
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
277-486 |
1.46e-10 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 63.59 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGrAYGKHITGKVKKDGKelllkNVRQAIENGLAYVTedRKTAGLVL 356
Cdd:PRK10535 22 EVLKGISLDIYAGEMVAIVGASGSGKSTL-MNILG-CLDKPTSGTYRVAGQ-----DVATLDADALAQLR--REHFGFIF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 idniKKNISLAKLGKLSKNQV------IDENKEIQVAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLI 430
Cdd:PRK10535 93 ----QRYHLLSHLTAAQNVEVpavyagLERKQRLLRAQELLQRLGL-EDRVEYQPSQLSGGQQQRVSIARALMNGGQVIL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 431 LDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSElPEILGMCDRIYVMNEGRIV 486
Cdd:PRK10535 168 ADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHD-PQVAAQAERVIEIRDGEIV 222
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
5-171 |
1.62e-10 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 63.16 E-value: 1.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFegnvcsfkdikdSEKIGI 84
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELE--PDSGTVKL------------GETVKI 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELA-LIPYLSIGENIFLGNErakngiiNWNTTHIKAteYLNRVGLK-ESSQTLIKDIGVG-KQQLVeIAKALAKD 161
Cdd:COG0488 381 GYFDQHQEeLDPDKTVLDELRDGAP-------GGTEQEVRG--YLGRFLFSgDDAFKPVGVLSGGeKARLA-LAKLLLSP 450
|
170
....*....|
gi 543000761 162 VKLLILDEPT 171
Cdd:COG0488 451 PNVLLLDEPT 460
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
274-490 |
2.09e-10 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 60.59 E-value: 2.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFgRAYgkHIT-GKVKKDGKELL---LKNVRQAIenglAYVTEDR 349
Cdd:cd03244 15 NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALF-RLV--ELSsGSILIDGVDISkigLHDLRSRI----SIIPQDP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 ktaglVLID-NIKKNisLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEV 428
Cdd:cd03244 88 -----VLFSgTIRSN--LDPFGEYSDEELWQALERVGLKEFVESLPGGLDTVVEEGGENLSVGQRQLLCLARALLRKSKI 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 429 LILDEPTRGIDvgakYEIYTIINKLAEE---GKSIIIISSELPEILGmCDRIYVMNEGRIVgELD 490
Cdd:cd03244 161 LVLDEATASVD----PETDALIQKTIREafkDCTVLTIAHRLDTIID-SDRILVLDKGRVV-EFD 219
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
3-223 |
2.55e-10 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 62.95 E-value: 2.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 3 EFILEMRNITKLFP-----------GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGN-V 70
Cdd:PRK10261 311 EPILQVRNLVTRFPlrsgllnrvtrEVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVE--SQGGEIIFNGQrI 388
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 71 CSFKDIK-DSEKIGIAIIHQE--LALIPYLSIGENIFlgNERAKNGIINWNTTHIKATEYLNRVGLK-ESSQTLIKDIGV 146
Cdd:PRK10261 389 DTLSPGKlQALRRDIQFIFQDpyASLDPRQTVGDSIM--EPLRVHGLLPGKAAAARVAWLLERVGLLpEHAWRYPHEFSG 466
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 147 GKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKH-GITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK10261 467 GQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQIVE 544
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
271-485 |
2.84e-10 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 62.17 E-value: 2.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 271 PVVDGkkviknVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRqAIENGLAYVTEDrk 350
Cdd:PRK09536 17 TVLDG------VDLSVREGSLVGLVGPNGAGKTTLLRAINGTL--TPTAGTVLVAGDDVEALSAR-AASRRVASVPQD-- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 tAGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSilQKTGNLSGGNQQKVVLSKWIFTDPEVLI 430
Cdd:PRK09536 86 -TSLSFEFDVRQVVEMGRTPHRSRFDTWTETDRAAVERAMERTGVAQFAD--RPVTSLSGGERQRVLLARALAQATPVLL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 431 LDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK09536 163 LDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRV 217
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
274-500 |
2.85e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 60.90 E-value: 2.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKELLLKNVRqaienglayvtEDRKTAG 353
Cdd:PRK13647 16 DGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQR--GRVKVMGREVNAENEK-----------WVRSKVG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLID--------NIKKNISLAKLG-KLSKNQVIDENKEIQVA---EELRRKlniksssilqKTGNLSGGNQQKVVLSKW 421
Cdd:PRK13647 83 LVFQDpddqvfssTVWDDVAFGPVNmGLDKDEVERRVEEALKAvrmWDFRDK----------PPYHLSYGQKKRVAIAGV 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 422 IFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKDASQESIM 500
Cdd:PRK13647 153 LAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDEDIV 231
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
6-175 |
2.97e-10 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 59.81 E-value: 2.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKdiKDSEKIGIA 85
Cdd:cd03231 1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSP--PLAGRVLLNGGPLDFQ--RDSIARGLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQELALIPYLSIGENI-FLGNERAKNGIInwntthikatEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:cd03231 77 YLGHAPGIKTTLSVLENLrFWHADHSDEQVE----------EALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPL 146
|
170
....*....|.
gi 543000761 165 LILDEPTAALN 175
Cdd:cd03231 147 WILDEPTTALD 157
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
276-501 |
3.10e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 61.00 E-value: 3.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGrAYGKHITGKVKKDGKELLLKNVRQAIEnglayvtEDRKTAGLV 355
Cdd:PRK13641 20 KKGLDNISFELEEGSFVALVGHTGSGKSTL-MQHFN-ALLKPSSGTITIAGYHITPETGNKNLK-------KLRKKVSLV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LI---DNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:PRK13641 91 FQfpeAQLFENTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLD 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 433 EPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVgeldqKDASQESIMK 501
Cdd:PRK13641 171 EPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLI-----KHASPKEIFS 234
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
21-177 |
4.19e-10 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 59.18 E-value: 4.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGnvcsfKDIKDSEKIGIAIIHQELALIPYLSIg 100
Cdd:cd03232 23 LNNISGYVKPGTLTALMGESGAGKTTLLDVLAGRKTAGVITGEILING-----RPLDKNFQRSTGYVEQQDVHSPNLTV- 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 101 eniflgnerakngiinwntthikateylnRVGLKESSqtLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEE 177
Cdd:cd03232 97 -----------------------------REALRFSA--LLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQ 142
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
275-483 |
4.26e-10 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 62.62 E-value: 4.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGK--------ELLLKNVRQAIENGLAYvT 346
Cdd:TIGR01271 438 VTPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSE--GKIKHSGRisfspqtsWIMPGTIKDNIIFGLSY-D 514
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 347 EDRKTAglvlidnikknislaklgklsknqVIdenKEIQVAEELrRKLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTD 425
Cdd:TIGR01271 515 EYRYTS------------------------VI---KACQLEEDI-ALFPEKDKTVLGEGGiTLSGGQRARISLARAVYKD 566
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIY-TIINKLAEEgKSIIIISSELpEILGMCDRIYVMNEG 483
Cdd:TIGR01271 567 ADLYLLDSPFTHLDVVTEKEIFeSCLCKLMSN-KTRILVTSKL-EHLKKADKILLLHEG 623
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
276-486 |
4.67e-10 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 62.03 E-value: 4.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGR------AYgkhITGKVKKDGKELLlknvrQAIENGLAYVTEDR 349
Cdd:PRK15134 22 RTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLlpsppvVY---PSGDIRFHGESLL-----HASEQTLRGVRGNK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 ktaglvlIDNIKKN--ISLAKLGKLSKnqvidenkeiQVAE--ELRRKLNIKSS-----SILQKTG-------------N 407
Cdd:PRK15134 94 -------IAMIFQEpmVSLNPLHTLEK----------QLYEvlSLHRGMRREAArgeilNCLDRVGirqaakrltdyphQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK15134 157 LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQElNMGLLFITHNLSIVRKLADRVAVMQNGRCV 236
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
21-219 |
6.55e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 60.13 E-value: 6.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKD-SEKIGIAIIHQELALIPyLSI 99
Cdd:PRK13650 23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLE--AESGQIIIDGDLLTEENVWDiRHKIGMVFQNPDNQFVG-ATV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 GENIFLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDS 179
Cdd:PRK13650 100 EDDVAFGLE---NKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGR 176
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 543000761 180 -DNLLELILELKKHGITSIIISHKLNEVmKVADSITVLRDG 219
Cdd:PRK13650 177 lELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNG 216
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
277-488 |
7.77e-10 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 60.14 E-value: 7.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRA--YGKHITGKVKKDGKELLL---KNVRQAIENGLAYVTEDRKT 351
Cdd:PRK11022 21 RAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIdyPGRVMAEKLEFNGQDLQRiseKERRNLVGAEVAMIFQDPMT 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 A-------GLVLIDNIKKNISLAKlgKLSKNQVIDENKEIQVAEELRRkLNIKSSsilqktgNLSGGNQQKVVLSKWIFT 424
Cdd:PRK11022 101 SlnpcytvGFQIMEAIKVHQGGNK--KTRRQRAIDLLNQVGIPDPASR-LDVYPH-------QLSGGMSQRVMIAMAIAC 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKLAE-EGKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK11022 171 RPKLLIADEPTTALDVTIQAQIIELLLELQQkENMALVLITHDLALVAEAAHKIIVMYAGQVVET 235
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
6-222 |
7.93e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 60.10 E-value: 7.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPG-----VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGNVCS-------- 72
Cdd:PRK13651 3 IKVKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKkktkekek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 73 --------------FKDIKDSEK-IGIAIIHQELALIPYlSIGENIFLG-------NERAKNgiinwntthiKATEYLNR 130
Cdd:PRK13651 83 vleklviqktrfkkIKKIKEIRRrVGVVFQFAEYQLFEQ-TIEKDIIFGpvsmgvsKEEAKK----------RAAKYIEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 131 VGLKESS-QTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKV 209
Cdd:PRK13651 152 VGLDESYlQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEW 231
|
250
....*....|...
gi 543000761 210 ADSITVLRDGATI 222
Cdd:PRK13651 232 TKRTIFFKDGKII 244
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
20-223 |
7.94e-10 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 61.27 E-value: 7.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGnvCSFKDIK-DSEKIGIAIIHQelalIPYL- 97
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVS--EGDIRFHD--IPLTKLQlDSWRSRLAVVSQ----TPFLf 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 98 --SIGENIFLGNERAKNGIInwntthikatEYLNRVG--------LKESSQTLIKDIGV----GKQQLVEIAKALAKDVK 163
Cdd:PRK10789 402 sdTVANNIALGRPDATQQEI----------EHVARLAsvhddilrLPQGYDTEVGERGVmlsgGQKQRISIARALLLNAE 471
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 164 LLILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:PRK10789 472 ILILDDALSAVDGR-TEHQILHNLRQWGEGRTVIISAHRLSALTE-ASEILVMQHGHIAQ 529
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
274-488 |
8.09e-10 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 60.97 E-value: 8.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKV-----------------------KKDGKEL- 329
Cdd:TIGR03269 11 DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEPTSGRIiyhvalcekcgyverpskvgepcPVCGGTLe 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 330 --------LLKNVRQAIENGLAYVTEdrKTAGL----VLIDNIKKniSLAKLGKLSKnqvidenKEIQVAEELRRKLNIk 397
Cdd:TIGR03269 91 peevdfwnLSDKLRRRIRKRIAIMLQ--RTFALygddTVLDNVLE--ALEEIGYEGK-------EAVGRAVDLIEMVQL- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 398 SSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILG-MCDR 476
Cdd:TIGR03269 159 SHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEdLSDK 238
|
250
....*....|..
gi 543000761 477 IYVMNEGRIVGE 488
Cdd:TIGR03269 239 AIWLENGEIKEE 250
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
340-482 |
9.06e-10 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 59.36 E-value: 9.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 340 NGLAYVTEDRKTAGLVLIDN--IKKNISLaKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSIL-------------QK 404
Cdd:PRK09544 39 NGAGKSTLVRVVLGLVAPDEgvIKRNGKL-RIGYVPQKLYLDTTLPLTVNRFLRLRPGTKKEDILpalkrvqaghlidAP 117
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 405 TGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNE 482
Cdd:PRK09544 118 MQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDLHLVMAKTDEVLCLNH 196
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
403-491 |
9.33e-10 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 60.11 E-value: 9.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 403 QKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILGMCDRIYVMN 481
Cdd:COG4148 129 RRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDELDiPILYVSHSLDEVARLADHVVLLE 208
|
90
....*....|..
gi 543000761 482 EGRIV--GELDQ 491
Cdd:COG4148 209 QGRVVasGPLAE 220
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
274-486 |
1.02e-09 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 60.23 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraYGKHITGKVKKDGKELLLKNVRQAIENGL--AYVTEDRKT 351
Cdd:PRK11607 30 DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAG--FEQPTAGQIMLDGVDLSHVPPYQRPINMMfqSYALFPHMT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 aglvlidnIKKNISLA-KLGKLSKNQVIDENKE----IQVAEELRRKLNiksssilqktgNLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK11607 108 --------VEQNIAFGlKQDKLPKAEIASRVNEmlglVHMQEFAKRKPH-----------QLSGGQRQRVALARSLAKRP 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 427 EVLILDEPTRGIDVGAK----YEIYTIINKLaeeGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK11607 169 KLLLLDEPMGALDKKLRdrmqLEVVDILERV---GVTCVMVTHDQEEAMTMAGRIAIMNRGKFV 229
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
16-234 |
1.03e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 61.53 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVK-ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGnvCsfkdikDSEKIGIAIIHQELALI 94
Cdd:PLN03232 1246 PGLPpVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVEL--EKGRIMIDD--C------DVAKFGLTDLRRVLSII 1315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 PYLSIgenIFLGNER-------AKNGIINWNT---THIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:PLN03232 1316 PQSPV---LFSGTVRfnidpfsEHNDADLWEAlerAHIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKI 1392
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 165 LILDEPTAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIETMVKDATVSED 234
Cdd:PLN03232 1393 LVLDEATASVDVR-TDSLIQRTIREEFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRD 1460
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
29-463 |
1.11e-09 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 60.95 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 29 KSGEVHALVGENGAGKSTLMSVLSG-IYP-YGSYSG-----DII--FEGNVCS--FKDIKDsEKIGIAIIHQELALIP-Y 96
Cdd:COG1245 97 KKGKVTGILGPNGIGKSTALKILSGeLKPnLGDYDEepswdEVLkrFRGTELQdyFKKLAN-GEIKVAHKPQYVDLIPkV 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 97 LS--IGENIFLGNERAKngiinwntthikATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAAL 174
Cdd:COG1245 176 FKgtVRELLEKVDERGK------------LDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYL 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 175 NEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVL--RDGA-TIETMVKDATVSEDRIIKG------MVGRDL 245
Cdd:COG1245 244 DIYQRLNVARLIRELAEEGKYVLVVEHDLAILDYLADYVHILygEPGVyGVVSKPKSVRVGINQYLDGylpeenVRIRDE 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 246 VNRF---PKREAKIGEIYFEIND----WNVFDPVVDGKKViknvnlkvHRGEVVGISGLMGSGRTELAmsvfgraygKHI 318
Cdd:COG1245 324 PIEFevhAPRREKEEETLVEYPDltksYGGFSLEVEGGEI--------REGEVLGIVGPNGIGKTTFA---------KIL 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 319 TGKVKKDGKELLLKnVR-----QaienglaYVTEDR-KTAGLVLIDNIKKNISlaklGKLSKNQVIdenkeiqvaeelrR 392
Cdd:COG1245 387 AGVLKPDEGEVDED-LKisykpQ-------YISPDYdGTVEEFLRSANTDDFG----SSYYKTEII-------------K 441
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 393 KLNIKSssILQKT-GNLSGGNQQKVV----LSKwiftDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIII 463
Cdd:COG1245 442 PLGLEK--LLDKNvKDLSGGELQRVAiaacLSR----DADLYLLDEPSAHLDVEQRLAVAKAIRRFAENrGKTAMVV 512
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
279-486 |
1.13e-09 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 60.80 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYGKHiTGKVKKDG---KELLLKNVRqaieNGLAYVTEDRKtaglV 355
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTIA-NLLTRFYDID-EGEILLDGhdlRDYTLASLR----NQVALVSQNVH----L 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLAKLGKLSKNQvIDENKEIQVAEELRRKLNIKSSSILQKTG-NLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:PRK11176 429 FNDTIANNIAYARTEQYSREQ-IEEAARMAYAMDFINKMDNGLDTVIGENGvLLSGGQRQRIAIARALLRDSPILILDEA 507
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 543000761 435 TRGIDVGAKYEIYTIINKLaEEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:PRK11176 508 TSALDTESERAIQAALDEL-QKNRTSLVIAHRLSTIEK-ADEILVVEDGEIV 557
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
270-484 |
1.15e-09 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 58.25 E-value: 1.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 270 DPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKkdgkelllknvrqaIENGLAYVTEdr 349
Cdd:cd03250 12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGEL--EKLSGSVS--------------VPGSIAYVSQ-- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 kTAGLV---LIDNIkknISLAKLGKLSKNQVIDenkeiqvAEELRRKLNIKSSSILQKTG----NLSGGNQQKVVLSKWI 422
Cdd:cd03250 74 -EPWIQngtIRENI---LFGKPFDEERYEKVIK-------ACALEPDLEILPDGDLTEIGekgiNLSGGQKQRISLARAV 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 423 FTDPEVLILDEPTRGID--VGAKyeIYT-IINKLAEEGKSIIIISSELpEILGMCDRIYVMNEGR 484
Cdd:cd03250 143 YSDADIYLLDDPLSAVDahVGRH--IFEnCILGLLLNNKTRILVTHQL-QLLPHADQIVVLDNGR 204
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
5-172 |
1.16e-09 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 58.89 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDS----- 79
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVK--PDSGRIFLDG-----EDITHLpmhkr 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGIAIIHQELALIPYLSIGENIflgneRAkngiinwntthIKATEYLNRVGLKESSQTLIKDIGVGK------QQL-- 151
Cdd:COG1137 76 ARLGIGYLPQEASIFRKLTVEDNI-----LA-----------VLELRKLSKKEREERLEELLEEFGITHlrkskaYSLsg 139
|
170 180
....*....|....*....|....*.
gi 543000761 152 -----VEIAKALAKDVKLLILDEPTA 172
Cdd:COG1137 140 gerrrVEIARALATNPKFILLDEPFA 165
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
21-174 |
1.32e-09 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 60.45 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGS-YSGDIIFEGNVCSFKDIKdseKIGiAIIHQELALIPYLSI 99
Cdd:TIGR00955 41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVkGSGSVLLNGMPIDAKEMR---AIS-AYVQQDDLFIPTLTV 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 GEN-IFLGNERAKNGIinwnTTHIK---ATEYLNRVGLKESSQTLI------KDIGVGKQQLVEIAKALAKDVKLLILDE 169
Cdd:TIGR00955 117 REHlMFQAHLRMPRRV----TKKEKrerVDEVLQALGLRKCANTRIgvpgrvKGLSGGERKRLAFASELLTDPPLLFCDE 192
|
....*
gi 543000761 170 PTAAL 174
Cdd:TIGR00955 193 PTSGL 197
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
21-255 |
1.41e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 60.91 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIIFEGnvCsfkdikDSEKIGIAIIHQELALIPYLSIg 100
Cdd:PLN03130 1255 LHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVEL--ERGRILIDG--C------DISKFGLMDLRKVLGIIPQAPV- 1323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 enIFLGNER-------AKNGIINWNT---THIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEP 170
Cdd:PLN03130 1324 --LFSGTVRfnldpfnEHNDADLWESlerAHLKDVIRRNSLGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEA 1401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 171 TAALNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE----------------TMVKDATVSED 234
Cdd:PLN03130 1402 TAAVDVR-TDALIQKTIREEFKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEfdtpenllsnegsafsKMVQSTGAANA 1479
|
250 260
....*....|....*....|.
gi 543000761 235 RIIKGMVGRDLVNRFPKREAK 255
Cdd:PLN03130 1480 QYLRSLVFGGDEDRLAREESK 1500
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
19-224 |
1.57e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 58.88 E-value: 1.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-P-YGSYS-GDIIFEGNVcSFKDIKD-SEKIGIAII---HQ-- 89
Cdd:PRK13634 21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLqPtSGTVTiGERVITAGK-KNKKLKPlRKKVGIVFQfpeHQlf 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 90 ELALIPYLSIG-ENIFLGNERAKNgiinwntthiKATEYLNRVGLKESsqTLIK---DIGVGKQQLVEIAKALAKDVKLL 165
Cdd:PRK13634 100 EETVEKDICFGpMNFGVSEEDAKQ----------KAREMIELVGLPEE--LLARspfELSGGQMRRVAIAGVLAMEPEVL 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 166 ILDEPTAALN----EEDSDnllELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIET 224
Cdd:PRK13634 168 VLDEPTAGLDpkgrKEMME---MFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQ 227
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
19-229 |
1.78e-09 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 59.33 E-value: 1.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVC---SFKDIKDSEKiGIAIIHQE-LA-L 93
Cdd:PRK15079 35 KAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVK--ATDGEVAWLGKDLlgmKDDEWRAVRS-DIQMIFQDpLAsL 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 IPYLSIGENIflgNERAKngiinwnTTHIKateyLNRVGLKESSQTLIKDIGV--------------GKQQLVEIAKALA 159
Cdd:PRK15079 112 NPRMTIGEII---AEPLR-------TYHPK----LSRQEVKDRVKAMMLKVGLlpnlinryphefsgGQCQRIGIARALI 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 160 KDVKLLILDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDA 229
Cdd:PRK15079 178 LEPKLIICDEPVSALDVSiQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDE 248
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
279-485 |
1.92e-09 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 58.12 E-value: 1.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLKNVRQaienglayvtedrKTAGLVLID 358
Cdd:cd03296 18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLE--RPDSGTILFGGEDATDVPVQE-------------RNVGFVFQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 359 -------NIKKNISLAklgkLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKT--GNLSGGNQQKVVLSKWIFTDPEVL 429
Cdd:cd03296 83 yalfrhmTVFDNVAFG----LRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRypAQLSGGQRQRVALARALAVEPKVL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 430 ILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:cd03296 159 LLDEPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRI 215
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
274-471 |
1.97e-09 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 57.24 E-value: 1.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKElllknVRQAIENGLAYV---TEDRK 350
Cdd:NF040873 3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLL---------KVLAGVLRPTSGT-----VRRAGGARVAYVpqrSEVPD 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 T-----AGLVLIDNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLniksssilqktGNLSGGNQQKVVLSKWIFTD 425
Cdd:NF040873 69 SlpltvRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQL-----------GELSGGQRQRALLAQGLAQE 137
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEIL 471
Cdd:NF040873 138 ADLLLLDEPTTGLDAESRERIIALLAEEHARGATVVVVTHDLELVR 183
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
274-484 |
2.02e-09 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 57.83 E-value: 2.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKK--VIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG--RAYGKHITgkVKKDGKEL-LLK-NVRQAIE---NGLAY 344
Cdd:COG4778 20 GGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGnyLPDSGSIL--VRHDGGWVdLAQaSPREILAlrrRTIGY 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 345 VTE-----DRKTAGLVLIDnikkniSLAKLGklsknqvIDENKEIQVAEELRRKLNIKSS--SILQKTgnLSGGNQQKVV 417
Cdd:COG4778 98 VSQflrviPRVSALDVVAE------PLLERG-------VDREEARARARELLARLNLPERlwDLPPAT--FSGGEQQRVN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 418 LSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:COG4778 163 IARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVADRVVDVTPFS 229
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
19-223 |
2.03e-09 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 57.42 E-value: 2.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 19 KALDNVNLKVKSGEVHALVGENGAGKSTL-MSVLSGIYPYgsySGDIIFEGnvcsfKDIKdseKIGIAIIHQELALIPYL 97
Cdd:cd03369 22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLiLALFRFLEAE---EGKIEIDG-----IDIS---TIPLEDLRSSLTIIPQD 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 98 SIgenIFLGNERAKNGIINwnttHIKATEYLNRVGLKESSQTLIKdigvGKQQLVEIAKALAKDVKLLILDEPTAALnEE 177
Cdd:cd03369 91 PT---LFSGTIRSNLDPFD----EYSDEEIYGALRVSEGGLNLSQ----GQRQLLCLARALLKRPRVLVLDEATASI-DY 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 543000761 178 DSDNLLELILELKKHGITSIIISHKLNEVMKVaDSITVLRDGATIE 223
Cdd:cd03369 159 ATDALIQKTIREEFTNSTILTIAHRLRTIIDY-DKILVMDAGEVKE 203
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
6-219 |
2.08e-09 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 55.92 E-value: 2.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGiypygsysGDIIFEGNVCSFKDIKdsekigIA 85
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAG--------ELEPDEGIVTWGSTVK------IG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQelalipyLSigeniflGNERAKngiinwntthikateylnrvglkessqtlikdigvgkqqlVEIAKALAKDVKLL 165
Cdd:cd03221 67 YFEQ-------LS-------GGEKMR----------------------------------------LALAKLLLENPNLL 92
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 166 ILDEPTAALneeDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03221 93 LLDEPTNHL---DLESIEALEEALKEYPGTVILVSHDRYFLDQVATKIIELEDG 143
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
275-488 |
2.23e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 58.57 E-value: 2.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVF---GRAYGKHITGKVKKDGKELLlkNVRQAIE--NGLAYVTEDR 349
Cdd:PRK14271 33 GKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNrmnDKVSGYRYSGDVLLGGRSIF--NYRDVLEfrRRVGMLFQRP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 KTAGLVLIDNIKKNISLAKLGKLSKNQVIDENK--EIQVAEELRRKLnikSSSILQktgnLSGGNQQKVVLSKWIFTDPE 427
Cdd:PRK14271 111 NPFPMSIMDNVLAGVRAHKLVPRKEFRGVAQARltEVGLWDAVKDRL---SDSPFR----LSGGQQQLLCLARTLAVNPE 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 428 VLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK14271 184 VLLLDEPTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFDGRLVEE 243
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
284-486 |
2.58e-09 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 57.12 E-value: 2.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 284 LKVHRGEVVGISGLMGSGRTELAMSVFGraygkhitgkvkkdgkeLLLKNVRQAIENGLAYVTED--RKTAGLVLIDN-- 359
Cdd:cd03298 19 LTFAQGEITAIVGPSGSGKSTLLNLIAG-----------------FETPQSGRVLINGVDVTAAPpaDRPVSMLFQENnl 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 360 -----IKKNISLAKLGKLSKNQVidENKEIQVAeelRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:cd03298 82 fahltVEQNVGLGLSPGLKLTAE--DRQAIEVA---LARVGL-AGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 435 TRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03298 156 FAALDPALRAEMLDLVLDLhAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIA 208
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
277-486 |
2.87e-09 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 59.45 E-value: 2.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYGKHiTGKVKKDGKELLL---KNVRQAIEnglayVTEDRktag 353
Cdd:PRK11160 354 PVLKGLSLQIKAGEKVALLGRTGCGKSTL-LQLLTRAWDPQ-QGEILLNGQPIADyseAALRQAIS-----VVSQR---- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 lVLI--DNIKKNISLAKlgklskNQVIDEnkeiqvaeelrrklniKSSSILQKTG--------------------NLSGG 411
Cdd:PRK11160 423 -VHLfsATLRDNLLLAA------PNASDE----------------ALIEVLQQVGleklleddkglnawlgeggrQLSGG 479
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 412 NQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGMcDRIYVMNEGRIV 486
Cdd:PRK11160 480 EQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHA-QNKTVLMITHRLTGLEQF-DRICVMDNGQII 552
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
261-486 |
2.98e-09 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 57.74 E-value: 2.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 261 FEINDWNVFdpvVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAY----GKHITGKVKKDGKELLLKNVRq 336
Cdd:COG1117 12 IEVRNLNVY---YGDKQALKDINLDIPENKVTALIGPSGCGKSTL-LRCLNRMNdlipGARVEGEILLDGEDIYDPDVD- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 337 aienglayVTEDRKTAGLV------LIDNIKKNISLA-KL-GKLSKnQVIDENKE---IQVA--EELRRKLNiKSSSilq 403
Cdd:COG1117 87 --------VVELRRRVGMVfqkpnpFPKSIYDNVAYGlRLhGIKSK-SELDEIVEeslRKAAlwDEVKDRLK-KSAL--- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 404 ktgNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIII----------ISselpeilgm 473
Cdd:COG1117 154 ---GLSGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD-YTIVIvthnmqqaarVS--------- 220
|
250
....*....|...
gi 543000761 474 cDRIYVMNEGRIV 486
Cdd:COG1117 221 -DYTAFFYLGELV 232
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
274-489 |
3.21e-09 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 57.79 E-value: 3.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNVRQA---IENGLAYVTEdrk 350
Cdd:PRK11248 12 GGKPALEDINLTLESGELLVVLGPSGCGKTTLL---------NLIAGFVPYQHGSITLDGKPVEgpgAERGVVFQNE--- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 taGLVLIDNIKKNISLA-KLGKLSKNQvidenkEIQVAEELRRKLNIKSSS---ILQktgnLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK11248 80 --GLLPWRNVQDNVAFGlQLAGVEKMQ------RLEIAHQMLKKVGLEGAEkryIWQ----LSGGQRQRVGIARALAANP 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVM--NEGRIVGEL 489
Cdd:PRK11248 148 QLLLLDEPFGALDAFTREQMQTLLLKLwQETGKQVLLITHDIEEAVFMATELVLLspGPGRVVERL 213
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
5-220 |
3.51e-09 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 59.64 E-value: 3.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVK--ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGiyPYGSYSGDIIFEGnvcsfKDIKDSeki 82
Cdd:TIGR01257 1937 ILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTG--DTTVTSGDATVAG-----KSILTN--- 2006
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 gIAIIHQELALIPYLSIGENIFLGNE-------------RAKNGIINWNTTHIKATEYLNRVGLKESSqtlikdigvGKQ 149
Cdd:TIGR01257 2007 -ISDVHQNMGYCPQFDAIDDLLTGREhlylyarlrgvpaEEIEKVANWSIQSLGLSLYADRLAGTYSG---------GNK 2076
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 150 QLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGA 220
Cdd:TIGR01257 2077 RKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGA 2147
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-222 |
3.70e-09 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 57.89 E-value: 3.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPygsYSGDIIFEGNVCSFKDIKDS 79
Cdd:PRK13537 3 MSVAPIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLtHP---DAGSISLCGEPVPSRARHAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EKIGiaIIHQELALIPYLSIGENI-----FLGNERAkngiinwnTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEI 154
Cdd:PRK13537 80 QRVG--VVPQFDNLDPDFTVRENLlvfgrYFGLSAA--------AARALVPPLLEFAKLENKADAKVGELSGGMKRRLTL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 155 AKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13537 150 ARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKI 217
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
408-495 |
3.79e-09 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 57.33 E-value: 3.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVg 487
Cdd:PRK11124 142 LSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIV- 220
|
....*...
gi 543000761 488 elDQKDAS 495
Cdd:PRK11124 221 --EQGDAS 226
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
274-467 |
3.98e-09 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 58.91 E-value: 3.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSvfgraygkhITGKVKKDGKELLLKNVRQAIENGlayvTEDRKTAG 353
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLAT---------LAGLLDPLQGEVTLDGVPVSSLDQ----DEVRRRVS 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LV-----LID-NIKKNISLAKlGKLSKNQVIDENKEIQVAEELRRkLNIKSSSILQKTGN-LSGGNQQKVVLSKWIFTDP 426
Cdd:TIGR02868 413 VCaqdahLFDtTVRENLRLAR-PDATDEELWAALERVGLADWLRA-LPDGLDTVLGEGGArLSGGERQRLALARALLADA 490
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKlAEEGKSIIIISSEL 467
Cdd:TIGR02868 491 PILLLDEPTEHLDAETADELLEDLLA-ALSGRTVVLITHHL 530
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
18-223 |
4.15e-09 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 58.20 E-value: 4.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSGEVHALVGENGAGKS----TLMSVLSGiypYGSYSGDIIFEGnvcsfKDI-----KDSEKI---GIA 85
Cdd:PRK09473 29 VTAVNDLNFSLRAGETLGIVGESGSGKSqtafALMGLLAA---NGRIGGSATFNG-----REIlnlpeKELNKLraeQIS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 86 IIHQE--LALIPYLSIGENIF--------LGNERAKNgiinwntthiKATEYLNRVGLKESSqtliKDIGV-------GK 148
Cdd:PRK09473 101 MIFQDpmTSLNPYMRVGEQLMevlmlhkgMSKAEAFE----------ESVRMLDAVKMPEAR----KRMKMyphefsgGM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 149 QQLVEIAKALAKDVKLLILDEPTAAL------------NEEDSD-NllelilelkkhgiTSII-ISHKLNEVMKVADSIT 214
Cdd:PRK09473 167 RQRVMIAMALLCRPKLLIADEPTTALdvtvqaqimtllNELKREfN-------------TAIImITHDLGVVAGICDKVL 233
|
....*....
gi 543000761 215 VLRDGATIE 223
Cdd:PRK09473 234 VMYAGRTME 242
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
425-490 |
4.49e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 57.79 E-value: 4.49e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV--GELD 490
Cdd:COG4586 172 RPKILFLDEPTIGLDVVSKEAIREFLKEYnRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIydGSLE 240
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
278-465 |
5.34e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 57.16 E-value: 5.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAY----GKHITGKVKKDGKELLLKNVRQaienglayvTEDRKTAG 353
Cdd:PRK14267 19 VIKGVDLKIPQNGVFALMGPSGCGKSTL-LRTFNRLLelneEARVEGEVRLFGRNIYSPDVDP---------IEVRREVG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVL-IDN------IKKNISLA-KLGKLSKNQV-IDEN-----KEIQVAEELRRKLNiksssilQKTGNLSGGNQQKVVLS 419
Cdd:PRK14267 89 MVFqYPNpfphltIYDNVAIGvKLNGLVKSKKeLDERvewalKKAALWDEVKDRLN-------DYPSNLSGGQRQRLVIA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 543000761 420 KWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISS 465
Cdd:PRK14267 162 RALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHS 207
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
274-486 |
5.95e-09 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 56.12 E-value: 5.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGK-HITGKVKKDG---KELLLKNVRQAIenglaYVTEDr 349
Cdd:cd03233 18 SKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvSVEGDIHYNGipyKEFAEKYPGEII-----YVSEE- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 ktaglvliDNikknislaklgklsknqvidENKEIQVAEELRRKLNIKSSSILQKtgnLSGGNQQKVVLSKWIFTDPEVL 429
Cdd:cd03233 92 --------DV--------------------HFPTLTVRETLDFALRCKGNEFVRG---ISGGERKRVSIAEALVSRASVL 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 430 ILDEPTRGIDVGAKYEIYTIINKLAEEGKS--IIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03233 141 CWDNSTRGLDSSTALEILKCIRTMADVLKTttFVSLYQASDEIYDLFDKVLVLYEGRQI 199
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
368-495 |
6.32e-09 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 56.56 E-value: 6.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 368 KLGKLSKNQVIDENKEIqvaeeLRR-KLNIKSSSI-LQktgnLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYE 445
Cdd:COG4161 109 KVLGLSKEQAREKAMKL-----LARlRLTDKADRFpLH----LSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQ 179
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 543000761 446 IYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVgelDQKDAS 495
Cdd:COG4161 180 VVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRII---EQGDAS 226
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
276-510 |
6.56e-09 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 56.56 E-value: 6.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKELLLKNVRQaiengLAyvtedRKTAGLV 355
Cdd:PRK11231 15 KRILNDLSLSLPTGKITALIGPNGCGKSTL-LKCFARLL-TPQSGTVFLGDKPISMLSSRQ-----LA-----RRLALLP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLAKL------------GKLSKnqviDENKEIQVAeelrrklniksssiLQKTG----------NLSGGNQ 413
Cdd:PRK11231 83 QHHLTPEGITVRELvaygrspwlslwGRLSA----EDNARVNQA--------------MEQTRinhladrrltDLSGGQR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 414 QKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIVGELDQKD 493
Cdd:PRK11231 145 QRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEE 224
|
250
....*....|....*..
gi 543000761 494 ASQESIMKCIMQSNREV 510
Cdd:PRK11231 225 VMTPGLLRTVFDVEAEI 241
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
6-177 |
7.23e-09 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 58.28 E-value: 7.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKAL-DNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIF-EGNVCSFkdikdsekig 83
Cdd:COG4178 363 LALEDLTLRTPDGRPLlEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYG--SGRIARpAGARVLF---------- 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 iaiIHQElaliPYLSIG---ENIFLGNERAkngiinwNTTHIKATEYLNRVGLkessQTLIKDIGV----------GKQQ 150
Cdd:COG4178 431 ---LPQR----PYLPLGtlrEALLYPATAE-------AFSDAELREALEAVGL----GHLAERLDEeadwdqvlslGEQQ 492
|
170 180
....*....|....*....|....*..
gi 543000761 151 LVEIAKALAKDVKLLILDEPTAALNEE 177
Cdd:COG4178 493 RLAFARLLLHKPDWLFLDEATSALDEE 519
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
274-486 |
7.94e-09 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 58.05 E-value: 7.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKK-VIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYGKHiTGKVKKDG---KELLLKNVRQAIenglAYVTEDr 349
Cdd:PRK13657 345 DNSRqGVEDVSFEAKPGQTVAIVGPTGAGKSTL-INLLQRVFDPQ-SGRILIDGtdiRTVTRASLRRNI----AVVFQD- 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 350 ktAGLvLIDNIKKNISLAKLGKlSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVL 429
Cdd:PRK13657 418 --AGL-FNRSIEDNIRVGRPDA-TDEEMRAAAERAQAHDFIERKPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPIL 493
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 430 ILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:PRK13657 494 ILDEATSALDVETEAKVKAALDELM-KGRTTFIIAHRLSTVRN-ADRILVFDNGRVV 548
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
259-486 |
8.84e-09 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 57.93 E-value: 8.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 259 IYFEINDWNVFDPvvDGKKVIKNVNLKVHRGEVVGISGLMGSGRTEL--AMSVFgRAYgkhiTGKVKKDG---KELLLKN 333
Cdd:PRK11174 348 VTIEAEDLEILSP--DGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLlnALLGF-LPY----QGSLKINGielRELDPES 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 334 VRQAiengLAYVTEDrktaGLVLIDNIKKNISLAKlGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQ 413
Cdd:PRK11174 421 WRKH----LSWVGQN----PQLPHGTLRDNVLLGN-PDASDEQLQQALENAWVSEFLPLLPQGLDTPIGDQAAGLSVGQA 491
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 414 QKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKlAEEGKSIIIISSELpEILGMCDRIYVMNEGRIV 486
Cdd:PRK11174 492 QRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQALNA-ASRRQTTLMVTHQL-EDLAQWDQIWVMQDGQIV 562
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
20-222 |
9.23e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 56.63 E-value: 9.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKD------------SEKIGIAI 86
Cdd:PRK13633 25 ALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLI--PSEGKVYVDGlDTSDEENLWDirnkagmvfqnpDNQIVATI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 87 IHQELALIPylsigENIFLGNERAKNgiinwntthiKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:PRK13633 103 VEEDVAFGP-----ENLGIPPEEIRE----------RVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECII 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 167 LDEPTAALNEED-SDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATI 222
Cdd:PRK13633 168 FDEPTAMLDPSGrREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVV 223
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
28-479 |
9.32e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 57.90 E-value: 9.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 28 VKSGEVHALVGENGAGKSTLMSVLSG-IYP-YGSYSG-----DII--FEGNVCS--FKDIKDSEkigIAIIH--QELALI 94
Cdd:PRK13409 96 PKEGKVTGILGPNGIGKTTAVKILSGeLIPnLGDYEEepswdEVLkrFRGTELQnyFKKLYNGE---IKVVHkpQYVDLI 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 P-YL--SIGENIFLGNERaknGIINwntthikatEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPT 171
Cdd:PRK13409 173 PkVFkgKVRELLKKVDER---GKLD---------EVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPT 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 172 AALNEEDSDNLLELILELKKhGITSIIISHKLNEVMKVADSITVL--RDGA-TIETMVKDATVSEDRIIKG------MVG 242
Cdd:PRK13409 241 SYLDIRQRLNVARLIRELAE-GKYVLVVEHDLAVLDYLADNVHIAygEPGAyGVVSKPKGVRVGINEYLKGylpeenMRI 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 243 RDLVNRF---PKREAKIGEIYFEINDWNV----FDPVVDGKkviknvnlKVHRGEVVGISGLMGSGRTELAmsvfgrayg 315
Cdd:PRK13409 320 RPEPIEFeerPPRDESERETLVEYPDLTKklgdFSLEVEGG--------EIYEGEVIGIVGPNGIGKTTFA--------- 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 316 KHITGKVKKDGKELLLKnVRqaiengLAYvtedrktaglvlidnikknislaklgklsKNQVIDENKEIQVAEELRRKLN 395
Cdd:PRK13409 383 KLLAGVLKPDEGEVDPE-LK------ISY-----------------------------KPQYIKPDYDGTVEDLLRSITD 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 396 IKSSS--------------ILQK-TGNLSGGNQQKVV----LSKwiftDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE 456
Cdd:PRK13409 427 DLGSSyykseiikplqlerLLDKnVKDLSGGELQRVAiaacLSR----DADLYLLDEPSAHLDVEQRLAVAKAIRRIAEE 502
|
490 500
....*....|....*....|....
gi 543000761 457 -GKSIIIISSELPEILGMCDRIYV 479
Cdd:PRK13409 503 rEATALVVDHDIYMIDYISDRLMV 526
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
21-201 |
9.82e-09 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 54.47 E-value: 9.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFegnvcsfkdikdSEKIGIAIIHQElaliPYLSIG 100
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWG--SGRIGM------------PEGEDLLFLPQR----PYLPLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 EniflgnerakngiinwntthikateylnrvgLKES-----SQTLikdiGVGKQQLVEIAKALAKDVKLLILDEPTAALn 175
Cdd:cd03223 79 T-------------------------------LREQliypwDDVL----SGGEQQRLAFARLLLHKPKFVFLDEATSAL- 122
|
170 180
....*....|....*....|....*.
gi 543000761 176 eeDSDNLLELILELKKHGITSIIISH 201
Cdd:cd03223 123 --DEESEDRLYQLLKELGITVISVGH 146
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
279-490 |
1.03e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 54.64 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKKDGKELL--LKNVRQAIENGLAYVTedrktaglvl 356
Cdd:cd03238 11 LQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGLYASGKARLISFLPKFSRNKLifIDQLQFLIDVGLGYLT---------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 357 idnikknislakLGklsknqvidenkeiqvaeelrrklniksssilQKTGNLSGGNQQKVVLSKWIFTDPE--VLILDEP 434
Cdd:cd03238 81 ------------LG--------------------------------QKLSTLSGGELQRVKLASELFSEPPgtLFILDEP 116
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEEGKSIIIISSElPEILGMCDRIYVMN--EGRIVGELD 490
Cdd:cd03238 117 STGLHQQDINQLLEVIKGLIDLGNTVILIEHN-LDVLSSADWIIDFGpgSGKSGGKVV 173
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
326-487 |
1.46e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 56.18 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 326 GKELLLKNVrqaieNGLAYVTEDRKTAGLVLIDNIKKNISLAKLGK-------LSKNQVIDEN--KEI-----------Q 385
Cdd:PRK13634 45 GKSTLLQHL-----NGLLQPTSGTVTIGERVITAGKKNKKLKPLRKkvgivfqFPEHQLFEETveKDIcfgpmnfgvseE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 386 VAEELRRKLnIK----SSSILQKTG-NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKS 459
Cdd:PRK13634 120 DAKQKAREM-IElvglPEELLARSPfELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLhKEKGLT 198
|
170 180
....*....|....*....|....*...
gi 543000761 460 IIIISSELPEILGMCDRIYVMNEGRIVG 487
Cdd:PRK13634 199 TVLVTHSMEDAARYADQIVVMHKGTVFL 226
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
276-486 |
1.74e-08 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 57.04 E-value: 1.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAYgKHITGKVKKDGKELLLKNVRqAIENGLAYVTEDRKTAGLV 355
Cdd:TIGR00958 494 VPVLKGLTFTLHPGEVVALVGPSGSGKSTVA-ALLQNLY-QPTGGQVLLDGVPLVQYDHH-YLHRQVALVGQEPVLFSGS 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIkknisLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPT 435
Cdd:TIGR00958 571 VRENI-----AYGLTDTPDEEIMAAAKAANAHDFIMEFPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEAT 645
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 543000761 436 RGIDVGAKYEIYTIINKlaeEGKSIIIISSELPeILGMCDRIYVMNEGRIV 486
Cdd:TIGR00958 646 SALDAECEQLLQESRSR---ASRTVLLIAHRLS-TVERADQILVLKKGSVV 692
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
22-240 |
1.98e-08 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 55.38 E-value: 1.98e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 22 DNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NVCSFKDIKDSEKIGIaiIHQELALIPYLSIG 100
Cdd:PRK10253 24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMT--PAHGHVWLDGeHIQHYASKEVARRIGL--LAQNATTPGDITVQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 ENIFLGNERAKNGIINWNTTHIKA-TEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALN-EED 178
Cdd:PRK10253 100 ELVARGRYPHQPLFTRWRKEDEEAvTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDiSHQ 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 179 SDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATVSEDRI--IKGM 240
Cdd:PRK10253 180 IDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIerIYGL 243
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
2-223 |
2.14e-08 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 56.64 E-value: 2.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITKLFPGVK-----------ALDNVNLKVKSGEVHALVGENGAGKSTL-MSVLSGIypygSYSGDIIFEGN 69
Cdd:PRK15134 272 ASPLLDVEQLQVAFPIRKgilkrtvdhnvVVKNISFTLRPGETLGLVGESGSGKSTTgLALLRLI----NSQGEIWFDGQ 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 70 VCSFKDIKDSEKI--GIAIIHQE--LALIPYLSIGENIFLGnERAKNGIINWNTTHIKATEYLNRVGLK-ESSQTLIKDI 144
Cdd:PRK15134 348 PLHNLNRRQLLPVrhRIQVVFQDpnSSLNPRLNVLQIIEEG-LRVHQPTLSAAQREQQVIAVMEEVGLDpETRHRYPAEF 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 145 GVGKQQLVEIAKALAKDVKLLILDEPTAALNEE-DSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK15134 427 SGGQRQRIAIARALILKPSLIILDEPTSSLDKTvQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVE 506
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
272-486 |
2.22e-08 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 55.85 E-value: 2.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 272 VVDGKKVIKNVNLKVHRGEVVGISGLMGSGRT---------ElamsvfgraygkHIT-GKVKKDGKELllknvrqaieNG 341
Cdd:COG3839 12 SYGGVEALKDIDLDIEDGEFLVLLGPSGCGKStllrmiaglE------------DPTsGEILIGGRDV----------TD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 342 LAyvTEDRKTAgLV-----LIDN--IKKNISLA-KLGKLSKnQVIDEnkeiQVAEELRRkLNIksSSILQ-KTGNLSGGN 412
Cdd:COG3839 70 LP--PKDRNIA-MVfqsyaLYPHmtVYENIAFPlKLRKVPK-AEIDR----RVREAAEL-LGL--EDLLDrKPKQLSGGQ 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 413 QQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG3839 139 RQRVALGRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLhRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQ 213
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
408-486 |
2.34e-08 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 56.04 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK11144 129 LSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINiPILYVSHSLDEILRLADRVVVLEQGKVK 208
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
3-223 |
2.35e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 55.23 E-value: 2.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 3 EFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSV---LSGIYPYGSYSGDI-IFEGNVCSFK--DI 76
Cdd:PRK14267 2 KFAIETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTfnrLLELNEEARVEGEVrLFGRNIYSPDvdPI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 77 KDSEKIGIaiIHQELALIPYLSIGENIFLGNERakNGIINWNTTHIKATEY-LNRVGLKESSQTLIKD----IGVGKQQL 151
Cdd:PRK14267 82 EVRREVGM--VFQYPNPFPHLTIYDNVAIGVKL--NGLVKSKKELDERVEWaLKKAALWDEVKDRLNDypsnLSGGQRQR 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 152 VEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHgITSIIISHKLNEVMKVADSITVLRDGATIE 223
Cdd:PRK14267 158 LVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLIE 228
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
5-105 |
2.48e-08 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 54.80 E-value: 2.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGnvcsfKDIkdsekigi 84
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGTVEFKG-----KDL-------- 67
|
90 100
....*....|....*....|.
gi 543000761 85 aiihqeLALIPYLSIGENIFL 105
Cdd:PRK09580 68 ------LELSPEDRAGEGIFM 82
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
277-491 |
2.49e-08 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 55.86 E-value: 2.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYgkHITGKVKKDGKELLLKNVRqaienglayvteDRKTaGLV- 355
Cdd:PRK10851 16 QVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEH--QTSGHIRFHGTDVSRLHAR------------DRKV-GFVf 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 ----------LIDNIKKNISLaklgkLSKNQVIDenkeiqvAEELRRKLnIKSSSILQKT-------GNLSGGNQQKVVL 418
Cdd:PRK10851 81 qhyalfrhmtVFDNIAFGLTV-----LPRRERPN-------AAAIKAKV-TQLLEMVQLAhladrypAQLSGGQKQRVAL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILGMCDRIYVMNEGRI--VGELDQ 491
Cdd:PRK10851 148 ARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKfTSVFVTHDQEEAMEVADRVVVMSQGNIeqAGTPDQ 223
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
5-214 |
2.70e-08 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 54.33 E-value: 2.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMS-VLSGIYPygsYSGDIIFEGnvcsfkdiKDSEKIG 83
Cdd:PRK10247 7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKiVASLISP---TSGTLLFEG--------EDISTLK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQEL---ALIPYLsIGENIFlgneraKNGIINWNTTHIKATE-----YLNRVGLKESS-QTLIKDIGVGKQQLVEI 154
Cdd:PRK10247 76 PEIYRQQVsycAQTPTL-FGDTVY------DNLIFPWQIRNQQPDPaifldDLERFALPDTIlTKNIAELSGGEKQRISL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 155 AKALAKDVKLLILDEPTAALNEEDSDNLLELI-LELKKHGITSIIISHKLNEVMKVADSIT 214
Cdd:PRK10247 149 IRNLQFMPKVLLLDEITSALDESNKHNVNEIIhRYVREQNIAVLWVTHDKDEINHADKVIT 209
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
28-219 |
2.77e-08 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 54.55 E-value: 2.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 28 VKSGEVHALVGENGAGKSTLMSVLSGIYPYgsySGDIIFEGNVCSfkdikdsekigiAIIHQELALI-PYLSIGEN---- 102
Cdd:PRK03695 19 VRAGEILHLVGPNGAGKSTLLARMAGLLPG---SGSIQFAGQPLE------------AWSAAELARHrAYLSQQQTppfa 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 103 --IF---------LGNERAKNGIINWNTTHIKATEYLNRvglkeSSQTLikdiGVGKQQLVEIAKALAK-------DVKL 164
Cdd:PRK03695 84 mpVFqyltlhqpdKTRTEAVASALNEVAEALGLDDKLGR-----SVNQL----SGGEWQRVRLAAVVLQvwpdinpAGQL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 165 LILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK03695 155 LLLDEPMNSLDVAQQAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQG 209
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-211 |
2.90e-08 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 54.79 E-value: 2.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSV---LSGIYPYGSYSGDIIFEGNVCSFKDIKD 78
Cdd:PRK14243 7 TETVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCfnrLNDLIPGFRVEGKVTFHGKNLYAPDVDP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SE-KIGIAIIHQELALIPYlSIGENIFLGN-------------ERAKNGIINWNTTHIKateylnrvgLKESSQTLikdi 144
Cdd:PRK14243 87 VEvRRRIGMVFQKPNPFPK-SIYDNIAYGAringykgdmdelvERSLRQAALWDEVKDK---------LKQSGLSL---- 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 145 GVGKQQLVEIAKALAKDVKLLILDEPTAALneedsDNLLELILELKKHGI----TSIIISHKLNEVMKVAD 211
Cdd:PRK14243 153 SGGQQQRLCIARAIAVQPEVILMDEPCSAL-----DPISTLRIEELMHELkeqyTIIIVTHNMQQAARVSD 218
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
280-485 |
2.90e-08 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 55.81 E-value: 2.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 280 KNVNLKVHRGEVVGISGLMGSGR-TELAMsvfgraygkhITGKVKKDGKELLLKNVRqaiengLAYVTEDRKTAGLV--- 355
Cdd:PRK11000 20 KDINLDIHEGEFVVFVGPSGCGKsTLLRM----------IAGLEDITSGDLFIGEKR------MNDVPPAERGVGMVfqs 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 --------LIDNIKKNISLAKLGKLSKNQVIDENKEI-QVAEELRRKlniksssilqkTGNLSGGNQQKVVLSKWIFTDP 426
Cdd:PRK11000 84 yalyphlsVAENMSFGLKLAGAKKEEINQRVNQVAEVlQLAHLLDRK-----------PKALSGGQRQRVAIGRTLVAEP 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK11000 153 SVFLLDEPLSNLDAALRVQMRIEISRLHKRlGRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
406-483 |
3.56e-08 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 56.56 E-value: 3.56e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 406 GNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:TIGR01257 2069 GTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
21-219 |
3.66e-08 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 56.04 E-value: 3.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSGDIIFEGNVCSFKDIKDsekigIAIIHQELALIPYLSIG 100
Cdd:PLN03211 84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNFTGTILANNRKPTKQILKR-----TGFVTQDDILYPHLTVR 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 EN-IFLGNERAKNGIINWNTTHIkATEYLNRVGLKESSQTL-----IKDIGVGKQQLVEIAKALAKDVKLLILDEPTAAL 174
Cdd:PLN03211 159 ETlVFCSLLRLPKSLTKQEKILV-AESVISELGLTKCENTIignsfIRGISGGERKRVSIAHEMLINPSLLILDEPTSGL 237
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 543000761 175 NEEDSDNLLELILELKKHGITSIIISHK-LNEVMKVADSITVLRDG 219
Cdd:PLN03211 238 DATAAYRLVLTLGSLAQKGKTIVTSMHQpSSRVYQMFDSVLVLSEG 283
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
405-486 |
3.83e-08 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 54.17 E-value: 3.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 405 TGNLSGGNQQKV-----VLSKWIFTDPE--VLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRI 477
Cdd:PRK03695 124 VNQLSGGEWQRVrlaavVLQVWPDINPAgqLLLLDEPMNSLDVAQQAALDRLLSELCQQGIAVVMSSHDLNHTLRHADRV 203
|
....*....
gi 543000761 478 YVMNEGRIV 486
Cdd:PRK03695 204 WLLKQGKLL 212
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
277-486 |
4.32e-08 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 54.91 E-value: 4.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGK-HITG-KVKKDGKELLLKNVRqaienglayvtEDRKTAGl 354
Cdd:COG4170 21 KAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwHVTAdRFRWNGIDLLKLSPR-----------ERRKIIG- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 vlidnikKNISL------------AKLGKLSKnQVIDE-----------NKEIQVAEELRRKLNIKS-SSILQKTGN-LS 409
Cdd:COG4170 89 -------REIAMifqepsscldpsAKIGDQLI-EAIPSwtfkgkwwqrfKWRKKRAIELLHRVGIKDhKDIMNSYPHeLT 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 410 GGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAE-EGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG4170 161 EGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHDLESISQWADTITVLYCGQTV 238
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
21-176 |
4.72e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 53.42 E-value: 4.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypYGSYSGDIIFEGNVCSfKDIKDSEKiGIAIIHQELALIPYLSIG 100
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGL--LNPEKGEILFERQSIK-KDLCTYQK-QLCFVGHRSGINPYLTLR 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 101 ENIFLGnerakngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNE 176
Cdd:PRK13540 93 ENCLYD--------IHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDE 160
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
5-56 |
4.74e-08 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 54.71 E-value: 4.74e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 5 ILEMRNITKLF------PG---------------VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YP 56
Cdd:COG4586 1 IIEVENLSKTYrvyekePGlkgalkglfrreyreVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGIlVP 74
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
21-222 |
5.25e-08 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 54.06 E-value: 5.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYS------GDIIFEGNVCSFKDIKDSEKIGIAIIHQELALI 94
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGAPrgarvtGDVTLNGEPLAAIDAPRLARLRAVLPQAAQPAF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 PYlSIGENIFLGN--ERAKNGIINWNTTHIkATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK---------DVK 163
Cdd:PRK13547 97 AF-SAREIVLLGRypHARRAGALTHRDGEI-AWQALALAGATALVGRDVTTLSGGELARVQFARVLAQlwpphdaaqPPR 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 164 LLILDEPTAALNEEDSDNLLELILELKKH---GITSIIisHKLNEVMKVADSITVLRDGATI 222
Cdd:PRK13547 175 YLLLDEPTAALDLAHQHRLLDTVRRLARDwnlGVLAIV--HDPNLAARHADRIAMLADGAIV 234
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
403-472 |
5.50e-08 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 53.25 E-value: 5.50e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 403 QKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILG 472
Cdd:COG4133 127 LPVRQLSAGQKRRVALARLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHLARGGAVLLTTHQPLELAA 196
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
273-486 |
5.63e-08 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 53.31 E-value: 5.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgkHIT-GKVKKDGKelllknVRQAIENGLAYVTEdrkt 351
Cdd:cd03220 32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTL-LRLLAGIY--PPDsGTVTVRGR------VSSLLGLGGGFNPE---- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 agLVLIDNIKKNISLakLGkLSKNQVIDENKEIQVAEELRRKLNiksssilQKTGNLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:cd03220 99 --LTGRENIYLNGRL--LG-LSRKEIDEKIDEIIEFSELGDFID-------LPVKTYSSGMKARLAFAIATALEPDILLI 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:cd03220 167 DEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIR 221
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
17-228 |
6.94e-08 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 53.73 E-value: 6.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 17 GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSysGDIIFEGNVCSfkdiKDSEKIGIAIIHQELAL--- 93
Cdd:PRK15056 19 GHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLAS--GKISILGQPTR----QALQKNLVAYVPQSEEVdws 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 IPYLSigENIFLGNERAKNGIINWNTTHIKA--TEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPT 171
Cdd:PRK15056 93 FPVLV--EDVVMMGRYGHMGWLRRAKKRDRQivTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPF 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 172 AALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSI-----TVLRDGATIETMVKD 228
Cdd:PRK15056 171 TGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTvmvkgTVLASGPTETTFTAE 232
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
279-485 |
8.13e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 53.58 E-value: 8.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKhiTGKVKKDGKELLLKNV---RQAIenGLAYVTEDRKTAGLV 355
Cdd:PRK13650 23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAE--SGQIIIDGDLLTEENVwdiRHKI--GMVFQNPDNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKknislakLGKLSKNQVIDENKE-IQVAEELRRKLNIKSssilQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:PRK13650 99 VEDDVA-------FGLENKGIPHEEMKErVNEALELVGMQDFKE----REPARLSGGQKQRVAIAGAVAMRPKIIILDEA 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEIlGMCDRIYVMNEGRI 485
Cdd:PRK13650 168 TSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLDEV-ALSDRVLVMKNGQV 218
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
408-486 |
8.34e-08 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 54.33 E-value: 8.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAK----YEIYTIinkLAEEGKSIIIISSELPEILGMCDRIYVMNEG 483
Cdd:COG3842 136 LSGGQQQRVALARALAPEPRVLLLDEPLSALDAKLReemrEELRRL---QRELGITFIYVTHDQEEALALADRIAVMNDG 212
|
...
gi 543000761 484 RIV 486
Cdd:COG3842 213 RIE 215
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-440 |
9.70e-08 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 54.56 E-value: 9.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITKLFPGVKA-LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypygsysgDIIFEGNVCSFKDIKdse 80
Cdd:TIGR03719 1 AQYIYTMNRVSKVVPPKKEiLKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV--------DKDFNGEARPQPGIK--- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 kigIAIIHQELALIPYLSIGENIFLGNERAKNGIINWN-----------------TTHIKATEYLNRVGLKESSQTL--- 140
Cdd:TIGR03719 70 ---VGYLPQEPQLDPTKTVRENVEEGVAEIKDALDRFNeisakyaepdadfdklaAEQAELQEIIDAADAWDLDSQLeia 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 141 ------------IKDIGVGKQQLVEIAKALAKDVKLLILDEPTaalNEEDSDNLLELILELKKHGITSIIISHKLNEVMK 208
Cdd:TIGR03719 147 mdalrcppwdadVTKLSGGERRRVALCRLLLSKPDMLLLDEPT---NHLDAESVAWLERHLQEYPGTVVAVTHDRYFLDN 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 209 VADSITVLRDGATI--------------ETMVKDATVSEDRiiKGMVGRDL--VNRFPK-REAK---------------- 255
Cdd:TIGR03719 224 VAGWILELDRGRGIpwegnysswleqkqKRLEQEEKEESAR--QKTLKRELewVRQSPKgRQAKskarlaryeellsqef 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 256 ----------------IGEIYFEINDwnvFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELamsvFgraygKHIT 319
Cdd:TIGR03719 302 qkrnetaeiyippgprLGDKVIEAEN---LTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTL----F-----RMIT 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 320 GKVKKDGKELLLKNVRQaiengLAYVTEDRKTaglvlIDNIK---KNIS----LAKLGklsknqvideNKEIQVAEELRR 392
Cdd:TIGR03719 370 GQEQPDSGTIEIGETVK-----LAYVDQSRDA-----LDPNKtvwEEISggldIIKLG----------KREIPSRAYVGR 429
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 543000761 393 kLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDV 440
Cdd:TIGR03719 430 -FNFKGSDQQKKVGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDV 476
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
262-486 |
1.02e-07 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 52.87 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 262 EINDWNVfdpVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKKDGKELllknvrqaieng 341
Cdd:PRK09580 3 SIKDLHV---SVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGTVEFKGKDL------------ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 342 LAYVTEDRKTAGLVL-------IDNIKK----NISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIkSSSILQKTGNL-- 408
Cdd:PRK09580 68 LELSPEDRAGEGIFMafqypveIPGVSNqfflQTALNAVRSYRGQEPLDRFDFQDLMEEKIALLKM-PEDLLTRSVNVgf 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 409 SGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIIsSELPEILGMC--DRIYVMNEGRIV 486
Cdd:PRK09580 147 SGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIV-THYQRILDYIkpDYVHVLYQGRIV 225
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
22-211 |
1.05e-07 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 53.23 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 22 DNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEG-NV--CSFKDIKDSEKiGIAIIHQELALIPYLS 98
Cdd:PRK11831 24 DNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIA--PDHGEILFDGeNIpaMSRSRLYTVRK-RMSMLFQSGALFTDMN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 99 IGENI---FLGNERAKNGIINwNTTHIKateyLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAAlN 175
Cdd:PRK11831 101 VFDNVaypLREHTQLPAPLLH-STVMMK----LEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVG-Q 174
|
170 180 190
....*....|....*....|....*....|....*...
gi 543000761 176 EEDSDNLLELILELKKH--GITSIIISHKLNEVMKVAD 211
Cdd:PRK11831 175 DPITMGVLVKLISELNSalGVTCVVVSHDVPEVLSIAD 212
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
18-178 |
1.06e-07 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 54.41 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSGEVH-----ALVGENGAGKSTLMSVLSG-IYPygsysgDiifEGNVcsFKDIKDSEKigiaiihqel 91
Cdd:COG1245 348 TKSYGGFSLEVEGGEIRegevlGIVGPNGIGKTTFAKILAGvLKP------D---EGEV--DEDLKISYK---------- 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 92 aliP-YLSIGENI----FLGNERAKNgiinWNTTHIKaTEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:COG1245 407 ---PqYISPDYDGtveeFLRSANTDD----FGSSYYK-TEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYL 478
|
170
....*....|..
gi 543000761 167 LDEPTAALNEED 178
Cdd:COG1245 479 LDEPSAHLDVEQ 490
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
21-219 |
1.06e-07 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 52.92 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygsYSGDIIFEGnvcsfKDIKDSEKIGIAII------HQE-LAL 93
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGLLP---GQGEILLNG-----RPLSDWSAAELARHraylsqQQSpPFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 IP---YLSIGeniflgneRAKNGiinwNTTHIKAT--EYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK-------D 161
Cdd:COG4138 84 MPvfqYLALH--------QPAGA----SSEAVEQLlaQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 162 VKLLILDEPTAALN-----------EEDSDnllelilelkkHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:COG4138 152 GQLLLLDEPMNSLDvaqqaaldrllRELCQ-----------QGITVVMSSHDLNHTLRHADRVWLLKQG 209
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
276-488 |
1.36e-07 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 52.85 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNvrqaiENgLAYVTEDRktaglv 355
Cdd:PRK11831 20 RCIFDNISLTVPRGKITAIMGPSGIGKTTLL---------RLIGGQIAPDHGEILFDG-----EN-IPAMSRSR------ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLAKLGKLSKNQVIDENkeiqVAEELRRKLNIKS----SSILQK-------------TGNLSGGNQQKVVL 418
Cdd:PRK11831 79 LYTVRKRMSMLFQSGALFTDMNVFDN----VAYPLREHTQLPApllhSTVMMKleavglrgaaklmPSELSGGMARRAAL 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 419 SKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVGE 488
Cdd:PRK11831 155 ARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIVAH 225
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
407-491 |
1.46e-07 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 53.23 E-value: 1.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYT-IINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:COG1118 133 QLSGGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRwLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRI 212
|
....*...
gi 543000761 486 --VGELDQ 491
Cdd:COG1118 213 eqVGTPDE 220
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
408-488 |
1.47e-07 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 52.44 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGID--VGAKyeiytIINKL----AEEGKSIIIISSElPEILGMCDRIYVMN 481
Cdd:COG4181 147 LSGGEQQRVALARAFATEPAILFADEPTGNLDaaTGEQ-----IIDLLfelnRERGTTLVLVTHD-PALAARCDRVLRLR 220
|
....*..
gi 543000761 482 EGRIVGE 488
Cdd:COG4181 221 AGRLVED 227
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
18-177 |
1.51e-07 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 52.41 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSG-----EVHALVGENGAGKSTLMSVLSG-IYPYGsysGDIIFEGNVCSFKdikdSEKIgiaIIHQEL 91
Cdd:cd03237 7 KKTLGEFTLEVEGGsisesEVIGILGPNGIGKTTFIKMLAGvLKPDE---GDIEIELDTVSYK----PQYI---KADYEG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 92 ALIPYLSigeniflgneraknGIINWNTTHIK-ATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEP 170
Cdd:cd03237 77 TVRDLLS--------------SITKDFYTHPYfKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEP 142
|
....*..
gi 543000761 171 TAALNEE 177
Cdd:cd03237 143 SAYLDVE 149
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
276-500 |
1.86e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 54.21 E-value: 1.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVkkdgkelllknvrqaIENGLAYVTEdrktAGLV 355
Cdd:PLN03232 630 KPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAETSSVV---------------IRGSVAYVPQ----VSWI 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLAklgklSKNQVIDENKEIQVAEeLRRKLNIKSSSILQKTG----NLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:PLN03232 691 FNATVRENILFG-----SDFESERYWRAIDVTA-LQHDLDLLPGRDLTEIGergvNISGGQKQRVSMARAVYSNSDIYIF 764
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELpEILGMCDRIYVMNEGRIVGELDQKDASQESIM 500
Cdd:PLN03232 765 DDPLSALDAHVAHQVFDSCMKDELKGKTRVLVTNQL-HFLPLMDRIILVSEGMIKEEGTFAELSKSGSL 832
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
278-485 |
1.94e-07 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 52.09 E-value: 1.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAmSVFGRAY----------GKHIT--------GKVKKDGKE--LLLKNVRQA 337
Cdd:cd03248 29 VLQDVSFTLHPGEVTALVGPSGSGKSTVV-ALLENFYqpqggqvlldGKPISqyehkylhSKVSLVGQEpvLFARSLQDN 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 338 IENGLAYVTEDRKTAGLVLIdNIKKNISLAKLGKlsknqvidenkeiqvaeelrrklnikSSSILQKTGNLSGGNQQKVV 417
Cdd:cd03248 108 IAYGLQSCSFECVKEAAQKA-HAHSFISELASGY--------------------------DTEVGEKGSQLSGGQKQRVA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 418 LSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKlAEEGKSIIIISSELPEIlGMCDRIYVMNEGRI 485
Cdd:cd03248 161 IARALIRNPQVLILDEATSALDAESEQQVQQALYD-WPERRTVLVIAHRLSTV-ERADQILVLDGGRI 226
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
268-490 |
2.06e-07 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 52.17 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 268 VFDPVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTEL--AMSVF-----GRAY--GKHITGKVKKDG----KELLL--K 332
Cdd:COG4525 12 RYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLlnLIAGFlapssGEITldGVPVTGPGADRGvvfqKDALLpwL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 333 NVRQAIENGLayvtedrktaglvlidnikknislaKLGKLSKNQvidenkEIQVAEELRRKLNIK---SSSILQktgnLS 409
Cdd:COG4525 92 NVLDNVAFGL-------------------------RLRGVPKAE------RRARAEELLALVGLAdfaRRRIWQ----LS 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 410 GGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVM--NEGRIV 486
Cdd:COG4525 137 GGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVwQRTGKGVFLITHSVEEALFLATRLVVMspGPGRIV 216
|
....
gi 543000761 487 GELD 490
Cdd:COG4525 217 ERLE 220
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
408-485 |
2.47e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 52.06 E-value: 2.47e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGK-SIIIISSELPEILGmCDRIYVMNEGRI 485
Cdd:PRK13648 143 LSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNiTIISITHDLSEAME-ADHVIVMNKGTV 220
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
5-177 |
2.48e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 53.40 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPygsYSGDIIFegnvcsfkdikdSEKIG 83
Cdd:TIGR03719 322 VIEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQeQP---DSGTIEI------------GETVK 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQEL-ALIPYLSIGENIFLGNErakngIINWNTTHIKATEYLNRVGLKESSQ-TLIKDIGVGKQQLVEIAKALAKD 161
Cdd:TIGR03719 387 LAYVDQSRdALDPNKTVWEEISGGLD-----IIKLGKREIPSRAYVGRFNFKGSDQqKKVGQLSGGERNRVHLAKTLKSG 461
|
170
....*....|....*.
gi 543000761 162 VKLLILDEPTAALNEE 177
Cdd:TIGR03719 462 GNVLLLDEPTNDLDVE 477
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
5-171 |
3.30e-07 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 51.65 E-value: 3.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGSYSgdiifegnvcsfkdIKDSEKIGI 84
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGV--------------IKRNGKLRI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 AIIHQELALIPYLSIGENIFLgneRAKNGIinwNTTHIKATeyLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKL 164
Cdd:PRK09544 70 GYVPQKLYLDTTLPLTVNRFL---RLRPGT---KKEDILPA--LKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQL 141
|
....*..
gi 543000761 165 LILDEPT 171
Cdd:PRK09544 142 LVLDEPT 148
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
21-252 |
3.56e-07 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 51.61 E-value: 3.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI-YPYGsysGDIIFEGnvcsfKDIKDSEKIGIAIIHQELALIPYLSI 99
Cdd:PRK10419 28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLeSPSQ---GNVSWRG-----EPLAKLNRAQRKAFRRDIQMVFQDSI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 100 GENiflgNERAKNG-IINWNTTHI----------KATEYLNRVGLKES-SQTLIKDIGVGKQQLVEIAKALAKDVKLLIL 167
Cdd:PRK10419 100 SAV----NPRKTVReIIREPLRHLlsldkaerlaRASEMLRAVDLDDSvLDKRPPQLSGGQLQRVCLARALAVEPKLLIL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 168 DEptaALNEED----SDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETmvkdATVSEDRIIKGMVGR 243
Cdd:PRK10419 176 DE---AVSNLDlvlqAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVET----QPVGDKLTFSSPAGR 248
|
250
....*....|...
gi 543000761 244 DLVNR----FPKR 252
Cdd:PRK10419 249 VLQNAvlpaFPVR 261
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
275-483 |
3.83e-07 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 50.79 E-value: 3.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKV---KKDGKELLLKNVRQAIENGLAYVTEDrkt 351
Cdd:cd03290 13 GLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEM--QTLEGKVhwsNKNESEPSFEATRSRNRYSVAYAAQK--- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 aGLVLIDNIKKNISL-AKLGKLSKNQVIDenkeiqvAEELRRKLNI----KSSSILQKTGNLSGGNQQKVVLSKWIFTDP 426
Cdd:cd03290 88 -PWLLNATVEENITFgSPFNKQRYKAVTD-------ACSLQPDIDLlpfgDQTEIGERGINLSGGQRQRICVARALYQNT 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 427 EVLILDEPTRGIDVGAKYEIYT--IINKLAEEGKSIIIISSELpEILGMCDRIYVMNEG 483
Cdd:cd03290 160 NIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRTLVLVTHKL-QYLPHADWIIAMKDG 217
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-103 |
3.84e-07 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 52.15 E-value: 3.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 1 MAEfiLEMRNITKLFPG-VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGNVCSfkDIKDS 79
Cdd:PRK11650 1 MAG--LKLQAVRKSYDGkTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERIT--SGEIWIGGRVVN--ELEPA 74
|
90 100
....*....|....*....|....
gi 543000761 80 EKiGIAIIHQELALIPYLSIGENI 103
Cdd:PRK11650 75 DR-DIAMVFQNYALYPHMSVRENM 97
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
274-485 |
3.87e-07 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 52.26 E-value: 3.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKNvrQAIENGLAyvtEDRKT-- 351
Cdd:PRK09452 25 DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVL---------RLIAGFETPDSGRIMLDG--QDITHVPA---ENRHVnt 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 --------AGLVLIDNIKKNISLAKLGKLS-KNQVIDENKEIQVAEELRRKLNiksssilqktgNLSGGNQQKVVLSKWI 422
Cdd:PRK09452 91 vfqsyalfPHMTVFENVAFGLRMQKTPAAEiTPRVMEALRMVQLEEFAQRKPH-----------QLSGGQQQRVAIARAV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK09452 160 VNKPKVLLLDESLSALDYKLRKQMQNELKALQRKlGITFVFVTHDQEEALTMSDRIVVMRDGRI 223
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
275-464 |
4.05e-07 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 52.37 E-value: 4.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVfgraygkhITGKVKKDGKELLLKN------------------VRQ 336
Cdd:COG0488 10 GRPLLDDVSLSINPGDRIGLVGRNGAGKSTL-LKI--------LAGELEPDSGEVSIPKglrigylpqeppldddltVLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 337 AIENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGKLSknQVIDENKEIQV---AEELRRKLNIKSSSILQKTGNLSGGNQ 413
Cdd:COG0488 81 TVLDGDAELRALEAELEELEAKLAEPDEDLERLAELQ--EEFEALGGWEAearAEEILSGLGFPEEDLDRPVSELSGGWR 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 414 QKVVLSKWIFTDPEVLILDEPTRGIDvgakyeIYTII---NKLAEEGKSIIIIS 464
Cdd:COG0488 159 RRVALARALLSEPDLLLLDEPTNHLD------LESIEwleEFLKNYPGTVLVVS 206
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
8-219 |
4.12e-07 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 50.72 E-value: 4.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 8 MRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYP-YGSYSGDIIFEGNvcSFKDIKDSEKIGIAI 86
Cdd:cd03233 10 SFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEgNVSVEGDIHYNGI--PYKEFAEKYPGEIIY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 87 IHQELALIPYLSIGENI-F----LGNErakngiinwntthikateylnrvglkessqtLIKDIGVGKQQLVEIAKALAKD 161
Cdd:cd03233 88 VSEEDVHFPTLTVRETLdFalrcKGNE-------------------------------FVRGISGGERKRVSIAEALVSR 136
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 162 VKLLILDEPTAALneeDSDN-----LLELILELKKHGITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:cd03233 137 ASVLCWDNSTRGL---DSSTaleilKCIRTMADVLKTTTFVSLYQASDEIYDLFDKVLVLYEG 196
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
324-483 |
4.93e-07 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 50.32 E-value: 4.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 324 KDGKELLLKNVRQAIENG---------------LAYVTEDRKTAGLV----LIDNIKKNISLAK-LGKLSKNQVidENKE 383
Cdd:cd03232 16 KGGKRQLLNNISGYVKPGtltalmgesgagkttLLDVLAGRKTAGVItgeiLINGRPLDKNFQRsTGYVEQQDV--HSPN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 384 IQVAEELRRKLNIKSSSILQKTgNLSGGnqqkVVLSkwifTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIII- 462
Cdd:cd03232 94 LTVREALRFSALLRGLSVEQRK-RLTIG----VELA----AKPSILFLDEPTSGLDSQAAYNIVRFLKKLADSGQAILCt 164
|
170 180
....*....|....*....|.
gi 543000761 463 ISSELPEILGMCDRIYVMNEG 483
Cdd:cd03232 165 IHQPSASIFEKFDRLLLLKRG 185
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
276-486 |
5.12e-07 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 50.85 E-value: 5.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKelllknVRQAIENGLAYVTEdrktagLV 355
Cdd:COG1134 39 FWALKDVSFEVERGESVGIIGRNGAGKSTL-LKLIAGIL-EPTSGRVEVNGR------VSALLELGAGFHPE------LT 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLakLGkLSKNQvIDEnKEIQVAE--ELRRKLNiksssilQKTGNLSGGNQQKVVLSKWIFTDPEVLILDE 433
Cdd:COG1134 105 GRENIYLNGRL--LG-LSRKE-IDE-KFDEIVEfaELGDFID-------QPVKTYSSGMRARLAFAVATAVDPDILLVDE 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 434 ptrGIDVG-----AKyeIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:COG1134 173 ---VLAVGdaafqKK--CLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRLV 225
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
268-485 |
6.09e-07 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 52.32 E-value: 6.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 268 VFDPVvdGKKVIKNVNLKVHRGEVVGISGLMGSGRTElAMSVfgraygkhITGKVKKDGKELLLKNvrQAIENGLAYVte 347
Cdd:TIGR01257 937 IFEPS--GRPAVDRLNITFYENQITAFLGHNGAGKTT-TLSI--------LTGLLPPTSGTVLVGG--KDIETNLDAV-- 1001
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 348 dRKTAGLVLIDNI--------KKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNiksssilQKTGNLSGGNQQKVVLS 419
Cdd:TIGR01257 1002 -RQSLGMCPQHNIlfhhltvaEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRN-------EEAQDLSGGMQRKLSVA 1073
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 420 KWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLaEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:TIGR01257 1074 IAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKY-RSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
276-486 |
6.31e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 50.95 E-value: 6.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG-RAYGKHITGKVKKDGKELLLKNVRQAIEN-GLAYVTEDRKTAG 353
Cdd:PRK13640 20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlLLPDDNPNSKITVDGITLTAKTVWDIREKvGIVFQNPDNQFVG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNIslaklgklsKNQVIDENKEIQVAEELRRKLNIkSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDE 433
Cdd:PRK13640 100 ATVGDDVAFGL---------ENRAVPRPEMIKIVRDVLADVGM-LDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDE 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 434 PTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEIlGMCDRIYVMNEGRIV 486
Cdd:PRK13640 170 STSMLDPAGKEQILKLIRKLKKKnNLTVISITHDIDEA-NMADQVLVLDDGKLL 222
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
6-56 |
7.51e-07 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 51.72 E-value: 7.51e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 6 LEMRNITKLFPGVK-----ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYP 56
Cdd:COG4615 328 LELRGVTYRYPGEDgdegfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYR 383
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
18-178 |
7.69e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 51.73 E-value: 7.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSGEVHA-----LVGENGAGKSTLMSVLSG-IYPygsysgDiifEGNVcsFKDIKDSEKigiaiihqel 91
Cdd:PRK13409 347 TKKLGDFSLEVEGGEIYEgevigIVGPNGIGKTTFAKLLAGvLKP------D---EGEV--DPELKISYK---------- 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 92 aliP-YLSIGENI----FLGNERAkngiiNWNTTHIKaTEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLI 166
Cdd:PRK13409 406 ---PqYIKPDYDGtvedLLRSITD-----DLGSSYYK-SEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYL 476
|
170
....*....|..
gi 543000761 167 LDEPTAALNEED 178
Cdd:PRK13409 477 LDEPSAHLDVEQ 488
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
6-224 |
7.95e-07 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 50.47 E-value: 7.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITkLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYG--SYSGDIIFEGNVCSFKDIKDsekIG 83
Cdd:PRK10418 5 IELRNIA-LQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPAGvrQTAGRVLLDGKPVAPCALRG---RK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 IAIIHQelalipylsigeniflgNER-AKNGIinwNTTHIKATEYLNRVGLKESSQTLI---KDIGV------------- 146
Cdd:PRK10418 81 IATIMQ-----------------NPRsAFNPL---HTMHTHARETCLALGKPADDATLTaalEAVGLenaarvlklypfe 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 147 ---GKQQLVEIAKALAKDVKLLILDEPTAalneeDSDNLLEL------ILELKKHGITSIIISHKLNEVMKVADSITVLR 217
Cdd:PRK10418 141 msgGMLQRMMIALALLCEAPFIIADEPTT-----DLDVVAQArildllESIVQKRALGMLLVTHDMGVVARLADDVAVMS 215
|
....*..
gi 543000761 218 DGATIET 224
Cdd:PRK10418 216 HGRIVEQ 222
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
277-486 |
1.08e-06 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 50.46 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgRAygkhI-------TGKVKKDGKELL------LKNVRQAIengla 343
Cdd:COG1135 19 TALDDVSLTIEKGEIFGIIGYSGAGKSTLI-----RC----InllerptSGSVLVDGVDLTalsereLRAARRKI----- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 344 yvtedrktaGLV-----LID--NIKKNISLA-KLGKLSKNQvIDEnkeiQVAE-----ELRRKLNiksssilQKTGNLSG 410
Cdd:COG1135 85 ---------GMIfqhfnLLSsrTVAENVALPlEIAGVPKAE-IRK----RVAEllelvGLSDKAD-------AYPSQLSG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 411 GNQQKV----VLSkwifTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:COG1135 144 GQKQRVgiarALA----NNPKVLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRICDRVAVLENGRI 219
|
.
gi 543000761 486 V 486
Cdd:COG1135 220 V 220
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-211 |
1.43e-06 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 49.65 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 2 AEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGI---YPYGSYSGDIIFEGnvcsfKDIKD 78
Cdd:COG1117 8 LEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMndlIPGARVEGEILLDG-----EDIYD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 79 SE--------KIGIaiIHQELALIPyLSIGENIFLGnerAK-NGIINWNTTHIKATEYLNRVG--------LKESSQTLI 141
Cdd:COG1117 83 PDvdvvelrrRVGM--VFQKPNPFP-KSIYDNVAYG---LRlHGIKSKSELDEIVEESLRKAAlwdevkdrLKKSALGLS 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 142 kdiGvGKQQLVEIAKALAKDVKLLILDEPTAALN-------EEdsdnlleLILELKKHgITSIIISHKLNEVMKVAD 211
Cdd:COG1117 157 ---G-GQQQRLCIARALAVEPEVLLMDEPTSALDpistakiEE-------LILELKKD-YTIVIVTHNMQQAARVSD 221
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
319-500 |
1.54e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 51.18 E-value: 1.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 319 TGKVKKDGKELLLKNVRQaIENGLAYVTEDRKTAGLVLIDNIK---KNISLAKLGKLSKNQVIDEnkeiqVAEELRRKLN 395
Cdd:PTZ00265 1276 SGKILLDGVDICDYNLKD-LRNLFSIVSQEPMLFNMSIYENIKfgkEDATREDVKRACKFAAIDE-----FIESLPNKYD 1349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 396 iksSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEI-YTIINKLAEEGKSIIIISSELPEIlGMC 474
Cdd:PTZ00265 1350 ---TNVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIeKTIVDIKDKADKTIITIAHRIASI-KRS 1425
|
170 180
....*....|....*....|....*.
gi 543000761 475 DRIYVMNEGRIVGELDQKDASQESIM 500
Cdd:PTZ00265 1426 DKIVVFNNPDRTGSFVQAHGTHEELL 1451
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
387-491 |
1.98e-06 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 49.73 E-value: 1.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 387 AEELRRKLNIKSSSiLQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSE 466
Cdd:NF000106 125 ADELLERFSLTEAA-GRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQY 203
|
90 100
....*....|....*....|....*..
gi 543000761 467 LPEILGMCDRIYVMNEGRIV--GELDQ 491
Cdd:NF000106 204 MEEAEQLAHELTVIDRGRVIadGKVDE 230
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
388-490 |
2.27e-06 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 48.72 E-value: 2.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 388 EELRRKLN--IKSSSILQKTGN----LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSII 461
Cdd:PRK10908 112 DDIRRRVSaaLDKVGLLDKAKNfpiqLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVL 191
|
90 100
....*....|....*....|....*....
gi 543000761 462 IISSELPEILGMCDRIYVMNEGRIVGELD 490
Cdd:PRK10908 192 MATHDIGLISRRSYRMLTLSDGHLHGGVG 220
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
408-485 |
2.32e-06 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 48.91 E-value: 2.32e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK11247 134 LSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
277-485 |
2.92e-06 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 48.86 E-value: 2.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 277 KVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRaygkhITG-KVKKDGKELLLKNVRQaiENGLAY-VTEDRKTAGL 354
Cdd:PRK09984 18 QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGL-----ITGdKSAGSHIELLGRTVQR--EGRLARdIRKSRANTGY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 V-----LIDNIK--KNISLAKLGKLSK-NQVIDENKEIQVAEELRRKLNIKSSSIL-QKTGNLSGGNQQKVVLSKWIFTD 425
Cdd:PRK09984 91 IfqqfnLVNRLSvlENVLIGALGSTPFwRTCFSWFTREQKQRALQALTRVGMVHFAhQRVSTLSGGQQQRVAIARALMQQ 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 426 PEVLILDEPTRGIDV-GAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK09984 171 AKVILADEPIASLDPeSARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHV 231
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
279-486 |
4.38e-06 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 48.88 E-value: 4.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgKHITGKVKKDGKELLL---KNVRQAIENGLAYVTEDRK-TAGL 354
Cdd:PRK10070 44 VKDASLAIEEGEIFVIMGLSGSGKSTM-VRLLNRLI-EPTRGQVLIDGVDIAKisdAELREVRRKKIAMVFQSFAlMPHM 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDNIKKNISLAKlgklsknqvidenkeiqVAEELRRKlniKSSSILQKTG----------NLSGGNQQKVVLSKWIFT 424
Cdd:PRK10070 122 TVLDNTAFGMELAG-----------------INAEERRE---KALDALRQVGlenyahsypdELSGGMRQRVGLARALAI 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK10070 182 NPDILLMDEAFSALDPLIRTEMQDELVKLqAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVV 244
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
408-484 |
4.72e-06 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 46.29 E-value: 4.72e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAkyeIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGR 484
Cdd:cd03221 71 LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLES---IEALEEALKEYPGTVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
16-218 |
5.50e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 49.26 E-value: 5.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 16 PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGS------------------------------------ 59
Cdd:PTZ00265 1179 PNVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNdhhivfknehtndmtneqdyqgdeeqnvgmknvnef 1258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 60 ----------------YSGDIIFEG-NVCSFkDIKDSEKIgIAIIHQELALIPyLSIGENIFLGNERAKNGIINWNTTHI 122
Cdd:PTZ00265 1259 sltkeggsgedstvfkNSGKILLDGvDICDY-NLKDLRNL-FSIVSQEPMLFN-MSIYENIKFGKEDATREDVKRACKFA 1335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 123 KATEYLNRVGLKESSQT--LIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSII-I 199
Cdd:PTZ00265 1336 AIDEFIESLPNKYDTNVgpYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIItI 1415
|
250
....*....|....*....
gi 543000761 200 SHKLNEVmKVADSITVLRD 218
Cdd:PTZ00265 1416 AHRIASI-KRSDKIVVFNN 1433
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
5-171 |
5.53e-06 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 49.35 E-value: 5.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIypygsysgDIIFEGNVCSF-KDIKDS---E 80
Cdd:NF033858 1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGA--------RKIQQGRVEVLgGDMADArhrR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIG--IAIIHQELA--LIPYLSIGENI-FLGN-------ERAKngiinwntthiKATEYLNRVGL---------KESsqt 139
Cdd:NF033858 73 AVCprIAYMPQGLGknLYPTLSVFENLdFFGRlfgqdaaERRR-----------RIDELLRATGLapfadrpagKLS--- 138
|
170 180 190
....*....|....*....|....*....|..
gi 543000761 140 likdiGVGKQQLvEIAKALAKDVKLLILDEPT 171
Cdd:NF033858 139 -----GGMKQKL-GLCCALIHDPDLLILDEPT 164
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
21-171 |
5.61e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 49.18 E-value: 5.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGS----YSGDIIF-----------EGNVCSFKdikdSEKIG-- 83
Cdd:PRK11147 19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDgriiYEQDLIVarlqqdpprnvEGTVYDFV----AEGIEeq 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 84 ---IAIIHQELALIPYLSIGENIflgNERAK--------NGiinWN-TTHIKatEYLNRVGLkeSSQTLIKDIGVGKQQL 151
Cdd:PRK11147 95 aeyLKRYHDISHLVETDPSEKNL---NELAKlqeqldhhNL---WQlENRIN--EVLAQLGL--DPDAALSSLSGGWLRK 164
|
170 180
....*....|....*....|
gi 543000761 152 VEIAKALAKDVKLLILDEPT 171
Cdd:PRK11147 165 AALGRALVSNPDVLLLDEPT 184
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
278-489 |
6.01e-06 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 47.50 E-value: 6.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGrAYGKHITGKVKKDGKEL--LLKNVRQAIEN---GLAYVTEDrkta 352
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTL-LHLLG-GLDTPTSGDVIFNGQPMskLSSAAKAELRNqklGFIYQFHH---- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 glVLID-NIKKNISLAKL-GKLSKNQVIDENKEIQVAEELRRKLNIKSSSilqktgnLSGGNQQKVVLSKWIFTDPEVLI 430
Cdd:PRK11629 98 --LLPDfTALENVAMPLLiGKKKPAEINSRALEMLAAVGLEHRANHRPSE-------LSGGERQRVAIARALVNNPRLVL 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 431 LDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELpEILGMCDRIYVMNEGRIVGEL 489
Cdd:PRK11629 169 ADEPTGNLDARNADSIFQLLGELnRLQGTAFLVVTHDL-QLAKRMSRQLEMRDGRLTAEL 227
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1-54 |
6.58e-06 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 48.58 E-value: 6.58e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 1 MAEFILEMRNITKLFPGVKA-LDNVNLK----VKSGevhaLVGENGAGKSTLMSVLSGI 54
Cdd:PRK11819 2 MAQYIYTMNRVSKVVPPKKQiLKDISLSffpgAKIG----VLGLNGAGKSTLLRIMAGV 56
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
17-219 |
6.86e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 49.14 E-value: 6.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 17 GVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG-IYPygsysgdiifegnvcSFKDIKDSEKIGIAiihQELALIP 95
Cdd:TIGR01271 438 VTPVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGeLEP---------------SEGKIKHSGRISFS---PQTSWIM 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YLSIGENIFLGnerakngiINWN----TTHIKATEYLNRVG-LKESSQTLIKDIGV----GKQQLVEIAKALAKDVKLLI 166
Cdd:TIGR01271 500 PGTIKDNIIFG--------LSYDeyryTSVIKACQLEEDIAlFPEKDKTVLGEGGItlsgGQRARISLARAVYKDADLYL 571
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 167 LDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLnEVMKVADSITVLRDG 219
Cdd:TIGR01271 572 LDSPFTHLDVVTEKEIFESCLCKLMSNKTRILVTSKL-EHLKKADKILLLHEG 623
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
28-216 |
7.82e-06 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 47.36 E-value: 7.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 28 VKSGEVHALVGENGAGKSTLMSVLSG--IYPYGSYSG-----DII--FEGNVCS--FKDIKDsEKIGIAIIHQELALIPY 96
Cdd:cd03236 23 PREGQVLGLVGPNGIGKSTALKILAGklKPNLGKFDDppdwdEILdeFRGSELQnyFTKLLE-GDVKVIVKPQYVDLIPK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 97 LSIGENIFLGNERAKNGIINwntthikatEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNE 176
Cdd:cd03236 102 AVKGKVGELLKKKDERGKLD---------ELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 543000761 177 EDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVL 216
Cdd:cd03236 173 KQRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCL 212
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
402-485 |
8.83e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 48.32 E-value: 8.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 402 LQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAkyeIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:PLN03073 622 LQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDA---VEALIQGLVLFQGGVLMVSHDEHLISGSVDELWVVS 698
|
....
gi 543000761 482 EGRI 485
Cdd:PLN03073 699 EGKV 702
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
281-491 |
1.09e-05 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 46.84 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 281 NVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKELLLKNVRQAIENGL--------AYVTED---- 348
Cdd:PRK11701 24 DVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDA--GEVHYRMRDGQLRDLYALSEAERrrllrtewGFVHQHprdg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 ---RKTAGlvlidnikKNIS--LAKLGKLSKNQVIDEnkeiqvAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIF 423
Cdd:PRK11701 102 lrmQVSAG--------GNIGerLMAVGARHYGDIRAT------AGDWLERVEIDAARIDDLPTTFSGGMQQRLQIARNLV 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 424 TDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMNEGRIV--GELDQ 491
Cdd:PRK11701 168 THPRLVFMDEPTGGLDVSVQARLLDLLRGLvRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVesGLTDQ 238
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
408-486 |
1.18e-05 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 48.02 E-value: 1.18e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAkyeIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK11147 157 LSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIET---IEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLV 232
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
24-177 |
1.26e-05 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 46.38 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 24 VNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYGsySGDIIFEGnvcsfKDIKDSEKIG-IAIIHQELALIPYLSIGEN 102
Cdd:PRK13543 30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVE--SGQIQIDG-----KTATRGDRSRfMAYLGHLPGLKADLSTLEN 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 103 I-FLgnerakNGIINWNTTHIKATEyLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNEE 177
Cdd:PRK13543 103 LhFL------CGLHGRRAKQMPGSA-LAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLE 171
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
408-470 |
1.46e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 48.10 E-value: 1.46e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEI 470
Cdd:PTZ00265 580 LSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLkGNENRITIIIAHRLSTI 643
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
6-68 |
1.48e-05 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 47.66 E-value: 1.48e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 6 LEMRNITKLFPGVK-ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIY-PygsYSGDIIFEG 68
Cdd:PRK10522 323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYqP---QSGEILLDG 384
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
262-439 |
1.66e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 46.31 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 262 EINDWNVFdpvVDGKKVIKNVNLKVHRGEVVGISGLMGSGRtelamSVFGRAYGKH--------ITGKVKKDGKELLLKN 333
Cdd:PRK14239 7 QVSDLSVY---YNKKKALNSVSLDFYPNEITALIGPSGSGK-----STLLRSINRMndlnpevtITGSIVYNGHNIYSPR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 334 VRqaienglayVTEDRKTAGLVLID------NIKKNISLA-KLGKLSKNQVIDEN-----KEIQVAEELRRKLNikSSSI 401
Cdd:PRK14239 79 TD---------TVDLRKEIGMVFQQpnpfpmSIYENVVYGlRLKGIKDKQVLDEAvekslKGASIWDEVKDRLH--DSAL 147
|
170 180 190
....*....|....*....|....*....|....*...
gi 543000761 402 lqktgNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGID 439
Cdd:PRK14239 148 -----GLSGGQQQRVCIARVLATSPKIILLDEPTSALD 180
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
279-464 |
1.71e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 46.31 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAY----GKHITGKVKKDGKELLLKNVRQAienglayvtEDRKTAGL 354
Cdd:PRK14243 26 VKNVWLDIPKNQITAFIGPSGCGKSTI-LRCFNRLNdlipGFRVEGKVTFHGKNLYAPDVDPV---------EVRRRIGM 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VL------IDNIKKNISL-AKLGKLSKNqvIDENKEI---QVA--EELRRKLNIKSSSilqktgnLSGGNQQKVVLSKWI 422
Cdd:PRK14243 96 VFqkpnpfPKSIYDNIAYgARINGYKGD--MDELVERslrQAAlwDEVKDKLKQSGLS-------LSGGQQQRLCIARAI 166
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 543000761 423 FTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIIIIS 464
Cdd:PRK14243 167 AVQPEVILMDEPCSALDPISTLRIEELMHELKEQ-YTIIIVT 207
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
408-486 |
1.77e-05 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 47.51 E-value: 1.77e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAeEGKSIIIISSELPEILGmCDRIYVMNEGRIV 486
Cdd:COG5265 495 LSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVA-RGRTTLVIAHRLSTIVD-ADEILVLEAGRIV 571
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
279-485 |
1.85e-05 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 47.63 E-value: 1.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVkkdgkelllknvrqAIENGLAYVTEDrktaGLVLID 358
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEM--DKVEGHV--------------HMKGSVAYVPQQ----AWIQND 713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 359 NIKKNISLAKlgklsknqVIDENKEIQVAEE--LRRKLNIKSS----SILQKTGNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:TIGR00957 714 SLRENILFGK--------ALNEKYYQQVLEAcaLLPDLEILPSgdrtEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFD 785
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 543000761 433 EPTRGIDVGAKYEIY--TIINKLAEEGKSIIIIS---SELPEIlgmcDRIYVMNEGRI 485
Cdd:TIGR00957 786 DPLSAVDAHVGKHIFehVIGPEGVLKNKTRILVThgiSYLPQV----DVIIVMSGGKI 839
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
6-53 |
1.97e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 47.19 E-value: 1.97e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG 53
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVG 367
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
3-53 |
2.16e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 47.41 E-value: 2.16e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 543000761 3 EFILEMRNITKLFPgVKA-----LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSG 53
Cdd:TIGR00956 757 EDIFHWRNLTYEVK-IKKekrviLNNVDGWVKPGTLTALMGASGAGKTTLLNVLAE 811
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
278-497 |
2.56e-05 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 46.25 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELllknVRQAIENG------LAYVTEDRKT 351
Cdd:PRK11432 21 VIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLE--KPTEGQIFIDGEDV----THRSIQQRdicmvfQSYALFPHMS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 352 AGlvliDNIKKNISLAKLGKLSKNQVIDEnkeiqvAEELRRKLNIKSSSILQktgnLSGGNQQKVVLSKWIFTDPEVLIL 431
Cdd:PRK11432 95 LG----ENVGYGLKMLGVPKEERKQRVKE------ALELVDLAGFEDRYVDQ----ISGGQQQRVALARALILKPKVLLF 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 432 DEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVgeldQKDASQE 497
Cdd:PRK11432 161 DEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGKIM----QIGSPQE 223
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
5-233 |
2.66e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 45.85 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 5 ILEMRNITKLF---PGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNVCSFKDIKD-SE 80
Cdd:PRK13642 4 ILEVENLVFKYekeSDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFE--EFEGKVKIDGELLTAENVWNlRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 KIGIAIIHQELALIPyLSIGENIFLGNErakNGIINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:PRK13642 82 KIGMVFQNPDNQFVG-ATVEDDVAFGME---NQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIAL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 161 DVKLLILDEPTAALNEED-SDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGatieTMVKDATVSE 233
Cdd:PRK13642 158 RPEIIILDESTSMLDPTGrQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAG----EIIKEAAPSE 226
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
426-485 |
2.72e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 47.04 E-value: 2.72e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELpeilgM-----CDRIYVMNEGRI 485
Cdd:NF033858 416 PELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHF-----MneaerCDRISLMHAGRV 475
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
276-485 |
2.83e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 47.04 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraygkhitgkvkkdgkEL-LLKNVRQAIENGLAYVTEdrktagL 354
Cdd:PLN03130 630 RPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLG----------------ELpPRSDASVVIRGTVAYVPQ------V 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 355 VLIDN--IKKNISLAklgklSKNQVIDENKEIQVAEeLRRKLNIKSSSILQKTG----NLSGGNQQKVVLSKWIFTDPEV 428
Cdd:PLN03130 688 SWIFNatVRDNILFG-----SPFDPERYERAIDVTA-LQHDLDLLPGGDLTEIGergvNISGGQKQRVSMARAVYSNSDV 761
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 429 LILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELpEILGMCDRIYVMNEGRI 485
Cdd:PLN03130 762 YIFDDPLSALDAHVGRQVFDKCIKDELRGKTRVLVTNQL-HFLSQVDRIILVHEGMI 817
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
376-482 |
3.28e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 46.55 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 376 QVI-DENKEIQVAEELRRKLNIksSSILQKT-GNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL 453
Cdd:PRK10938 104 EIIqDEVKDPARCEQLAQQFGI--TALLDRRfKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASL 181
|
90 100
....*....|....*....|....*....
gi 543000761 454 AEEGKSIIIISSELPEILGMCDRIYVMNE 482
Cdd:PRK10938 182 HQSGITLVLVLNRFDEIPDFVQFAGVLAD 210
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
407-503 |
5.34e-05 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 44.78 E-value: 5.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK10575 147 SLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEM 226
|
90
....*....|....*...
gi 543000761 486 VGELDQKDASQESIMKCI 503
Cdd:PRK10575 227 IAQGTPAELMRGETLEQI 244
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
21-213 |
5.76e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 45.93 E-value: 5.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGiyPYGSYSGDIIFEGNvcsfkdikdsekIGIAIIHQEL-AL----IP 95
Cdd:PRK10636 17 LDNATATINPGQKVGLVGKNGCGKSTLLALLKN--EISADGGSYTFPGN------------WQLAWVNQETpALpqpaLE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YLSIGENIF--------LGNER----------AKNGIINWNTTHIKATEYLNRVGL-KESSQTLIKDIGVGKQQLVEIAK 156
Cdd:PRK10636 83 YVIDGDREYrqleaqlhDANERndghaiatihGKLDAIDAWTIRSRAASLLHGLGFsNEQLERPVSDFSGGWRMRLNLAQ 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 157 ALAKDVKLLILDEPTaalNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSI 213
Cdd:PRK10636 163 ALICRSDLLLLDEPT---NHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKI 216
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
10-439 |
6.48e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 45.65 E-value: 6.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 10 NITKLFpGVKAL-DNVNLKVKSGEVHALVGENGAGKSTLMSVLSG-IYPYGsysgdiifeGNVcsfkDIKDSEKIGI--- 84
Cdd:PRK15064 6 NITMQF-GAKPLfENISVKFGGGNRYGLIGANGCGKSTFMKILGGdLEPSA---------GNV----SLDPNERLGKlrq 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 85 ------------AII--HQEL-----------ALiPYLSIGENIFLGNERAKNGIINWNTTHIKATEYLNRVGLKESSQT 139
Cdd:PRK15064 72 dqfafeeftvldTVImgHTELwevkqerdriyAL-PEMSEEDGMKVADLEVKFAEMDGYTAEARAGELLLGVGIPEEQHY 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 140 -LIKDIGVGKQQLVEIAKALAKDVKLLILDEPT------------AALNEEDSdnllelilelkkhgiTSIIISHK---L 203
Cdd:PRK15064 151 gLMSEVAPGWKLRVLLAQALFSNPDILLLDEPTnnldintirwleDVLNERNS---------------TMIIISHDrhfL 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 204 NEV-MKVAD----SITVL----RDGATIETMVKDATVSEDRIIKGMVG--RDLVNRFP----------KREAKIGEIYFE 262
Cdd:PRK15064 216 NSVcTHMADldygELRVYpgnyDEYMTAATQARERLLADNAKKKAQIAelQSFVSRFSanaskakqatSRAKQIDKIKLE 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 263 -------INDWNVFDP---------VV-------DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHIT 319
Cdd:PRK15064 296 evkpssrQNPFIRFEQdkklhrnalEVenltkgfDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGEL--EPDS 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 320 GKVKKDgkelllknvrqaiENG-LAYVTEDRKTA---GLVLIDNIkknislaklgklskNQVIDENKEIQVAEELRRKLN 395
Cdd:PRK15064 374 GTVKWS-------------ENAnIGYYAQDHAYDfenDLTLFDWM--------------SQWRQEGDDEQAVRGTLGRLL 426
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 543000761 396 IKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGID 439
Cdd:PRK15064 427 FSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMD 470
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
278-485 |
7.63e-05 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 44.00 E-value: 7.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 278 VIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKhiTGKVKkdgkeLLLKNVRQAIENGLAYVTEdrKTAGLV-- 355
Cdd:PRK10584 25 ILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGS--SGEVS-----LVGQPLHQMDEEARAKLRA--KHVGFVfq 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 ---LID--NIKKNISLAKL-----GKLSKNQVIDENKEIQVAEELRrklniksssilQKTGNLSGGNQQKVVLSKWIFTD 425
Cdd:PRK10584 96 sfmLIPtlNALENVELPALlrgesSRQSRNGAKALLEQLGLGKRLD-----------HLPAQLSGGEQQRVALARAFNGR 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 426 PEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI 485
Cdd:PRK10584 165 PDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRLRLVNGQL 224
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
6-219 |
7.66e-05 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 44.00 E-value: 7.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNIT-----KLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfkdikdse 80
Cdd:cd03250 1 ISVEDASftwdsGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELE--KLSGSVSVPG------------ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 81 kiGIAIIHQElaliPYL---SIGENIFLGNERAKngiinwntthikatEYLNRV-----------GLKESSQTLIKDIGV 146
Cdd:cd03250 67 --SIAYVSQE----PWIqngTIRENILFGKPFDE--------------ERYEKVikacalepdleILPDGDLTEIGEKGI 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 147 ----GKQQLVEIAKALAKDVKLLILDEPTAALneeDS-------DNlleLILELKKHGITSIIISHKLnEVMKVADSITV 215
Cdd:cd03250 127 nlsgGQKQRISLARAVYSDADIYLLDDPLSAV---DAhvgrhifEN---CILGLLLNNKTRILVTHQL-QLLPHADQIVV 199
|
....
gi 543000761 216 LRDG 219
Cdd:cd03250 200 LDNG 203
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
275-486 |
8.88e-05 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 44.38 E-value: 8.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 275 GKKVIKNVNLKVHRGEVVGISGLMGSGRTEL--AMSVFGRAYgkhiTGKVKKDGKELllknvrqaienglayvtEDRKTA 352
Cdd:PRK13548 14 GRTLLDDVSLTLRPGEVVAILGPNGAGKSTLlrALSGELSPD----SGEVRLNGRPL-----------------ADWSPA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 353 GL-----VLidniKKNISLA---------KLGKLSKNQVIDENKEIqVAEELRRK--LNIKSSSILQktgnLSGGNQQKV 416
Cdd:PRK13548 73 ELarrraVL----PQHSSLSfpftveevvAMGRAPHGLSRAEDDAL-VAAALAQVdlAHLAGRDYPQ----LSGGEQQRV 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 417 ----VLSK-WIFT-DPEVLILDEPTRGIDVGAKYEIYTIINKLA-EEGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK13548 144 qlarVLAQlWEPDgPPRWLLLDEPTSALDLAHQHHVLRLARQLAhERGLAVIVVLHDLNLAARYADRIVLLHQGRLV 220
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
279-486 |
8.99e-05 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 44.31 E-value: 8.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG--RAYGKHITGKVKKDGKEL------------LLKNVRQAIENGLAY 344
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGilPAGVRQTAGRVLLDGKPVapcalrgrkiatIMQNPRSAFNPLHTM 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 345 VTEDRKTaglvlidnikknisLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSilqktgnLSGGNQQKVVLSKWIFT 424
Cdd:PRK10418 99 HTHARET--------------CLALGKPADDATLTAALEAVGLENAARVLKLYPFE-------MSGGMLQRMMIALALLC 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 543000761 425 DPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK10418 158 EAPFIIADEPTTDLDVVAQARILDLLESIVQKrALGMLLVTHDMGVVARLADDVAVMSHGRIV 220
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
6-174 |
9.31e-05 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 43.64 E-value: 9.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNIT------KLFpgvkalDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGnvcsfKDIKDS 79
Cdd:PRK13538 2 LEARNLAcerderILF------SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLAR--PDAGEVLWQG-----EPIRRQ 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 80 EkigiAIIHQELALI-------PYLSIGENI-FLGnerAKNGIINWNTTHikatEYLNRVGLKESSQTLIKDIGVGKQQL 151
Cdd:PRK13538 69 R----DEYHQDLLYLghqpgikTELTALENLrFYQ---RLHGPGDDEALW----EALAQVGLAGFEDVPVRQLSAGQQRR 137
|
170 180
....*....|....*....|...
gi 543000761 152 VEIAKALAKDVKLLILDEPTAAL 174
Cdd:PRK13538 138 VALARLWLTRAPLWILDEPFTAI 160
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
273-486 |
1.11e-04 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 44.41 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGKKVI--KNVNLKVHRGEVVGISGLMGSGrtelamsvfgraygkhitgkvkkdgKELLLKNVrqaieNGLayvteDRK 350
Cdd:PRK11153 13 QGGRTIHalNNVSLHIPAGEIFGVIGASGAG-------------------------KSTLIRCI-----NLL-----ERP 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 351 TAGLVLIDNIKknislakLGKLSKNQVIDENKEI----Q---------VAE------EL--RRKLNIKS--SSILQKTG- 406
Cdd:PRK11153 58 TSGRVLVDGQD-------LTALSEKELRKARRQIgmifQhfnllssrtVFDnvalplELagTPKAEIKArvTELLELVGl 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 ---------NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDR 476
Cdd:PRK11153 131 sdkadrypaQLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDR 210
|
250
....*....|
gi 543000761 477 IYVMNEGRIV 486
Cdd:PRK11153 211 VAVIDAGRLV 220
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
18-218 |
1.11e-04 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 45.02 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 18 VKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYpyGSYSGDIIFEgNVCSFKDIKDS---EKIGIaiIHQELALI 94
Cdd:PTZ00265 398 VEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLY--DPTEGDIIIN-DSHNLKDINLKwwrSKIGV--VSQDPLLF 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 95 PYlSIGENI-----------FLGNERAKNGIINW------NTTHIKATEYLNRV-------GLKE--------------- 135
Cdd:PTZ00265 473 SN-SIKNNIkyslyslkdleALSNYYNEDGNDSQenknkrNSCRAKCAGDLNDMsnttdsnELIEmrknyqtikdsevvd 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 136 -SSQTLIKD-------------------IGVGKQQLVEIAKALAKDVKLLILDEPTAAL-NEEDSDNLLELILELKKHGI 194
Cdd:PTZ00265 552 vSKKVLIHDfvsalpdkyetlvgsnaskLSGGQKQRISIARAIIRNPKILILDEATSSLdNKSEYLVQKTINNLKGNENR 631
|
250 260
....*....|....*....|....
gi 543000761 195 TSIIISHKLNEVmKVADSITVLRD 218
Cdd:PTZ00265 632 ITIIIAHRLSTI-RYANTIFVLSN 654
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
17-221 |
1.19e-04 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 44.08 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 17 GVKALDNVNLKVKSGEVHALVGENGAGKSTL-MSVLSGIYPygsysgdiifegnvcSFKDIKDSEKIGIAiihQELALIP 95
Cdd:cd03291 49 GAPVLKNINLKIEKGEMLAITGSTGSGKTSLlMLILGELEP---------------SEGKIKHSGRISFS---SQFSWIM 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 96 YLSIGENIFLG----NERAKngiinwntTHIKATEYLNRVG-LKESSQTLIKDIGV----GKQQLVEIAKALAKDVKLLI 166
Cdd:cd03291 111 PGTIKENIIFGvsydEYRYK--------SVVKACQLEEDITkFPEKDNTVLGEGGItlsgGQRARISLARAVYKDADLYL 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 167 LDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLnEVMKVADSITVLRDGAT 221
Cdd:cd03291 183 LDSPFGYLDVFTEKEIFESCVCKLMANKTRILVTSKM-EHLKKADKILILHEGSS 236
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
407-490 |
1.39e-04 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 44.73 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINklaEEGKS--IIIISSELPEILGmCDRIYVMNEGR 484
Cdd:PLN03130 1374 NFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDALIQKTIR---EEFKSctMLIIAHRLNTIID-CDRILVLDAGR 1449
|
....*.
gi 543000761 485 IVgELD 490
Cdd:PLN03130 1450 VV-EFD 1454
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
409-494 |
1.42e-04 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 43.80 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 409 SGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRIYVMNEGRIVg 487
Cdd:PRK11308 156 SGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQElGLSYVFISHDLSVVEHIADEVMVMYLGRCV- 234
|
....*..
gi 543000761 488 ELDQKDA 494
Cdd:PRK11308 235 EKGTKEQ 241
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
273-494 |
1.50e-04 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 43.95 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 273 VDGkkviknVNLKVHRGEVVGISGLMGSGRTELamsvfGRAygkhIT-------GKVKKDGKELL------LKNVRQAIE 339
Cdd:COG4608 34 VDG------VSFDIRRGETLGLVGESGCGKSTL-----GRL----LLrleeptsGEILFDGQDITglsgreLRPLRRRMQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 340 nglaYVTED-------RKTAGlvlidnikknislaklgklsknQVIDENKEIQ---VAEELRRKLNikssSILQKTG--- 406
Cdd:COG4608 99 ----MVFQDpyaslnpRMTVG----------------------DIIAEPLRIHglaSKAERRERVA----ELLELVGlrp 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 --------NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEE-GKSIIIISSELPEILGMCDRI 477
Cdd:COG4608 149 ehadryphEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDElGLTYLFISHDLSVVRHISDRV 228
|
250
....*....|....*..
gi 543000761 478 YVMNEGRIVgELDQKDA 494
Cdd:COG4608 229 AVMYLGKIV-EIAPRDE 244
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-56 |
1.65e-04 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 44.35 E-value: 1.65e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 2 AEFILEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYP 56
Cdd:NF033858 263 DEPAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLP 317
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
408-486 |
1.72e-04 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 43.64 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAE-EGKSIIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQnNNTTILLISHDLQMLSQWADKINVLYCGQTV 238
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
408-464 |
2.69e-04 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 43.64 E-value: 2.69e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIinkLAEEGKSIIIIS 464
Cdd:COG4178 486 LSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQL---LREELPGTTVIS 539
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
21-223 |
3.11e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 43.78 E-value: 3.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGiyPYGSYSGDIIFEGNVcsfkdikdsekigiAIIHQElALIPYLSIG 100
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLA--EMDKVEGHVHMKGSV--------------AYVPQQ-AWIQNDSLR 716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 ENIFLGNERAKngiiNWNTTHIKATEYLNRVG-LKESSQTLIKDIGV----GKQQLVEIAKALAKDVKLLILDEPTAALN 175
Cdd:TIGR00957 717 ENILFGKALNE----KYYQQVLEACALLPDLEiLPSGDRTEIGEKGVnlsgGQKQRVSLARAVYSNADIYLFDDPLSAVD 792
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 176 EEDSDNLLELIL--ELKKHGITSIIISHKLNEVMKVaDSITVLRDGATIE 223
Cdd:TIGR00957 793 AHVGKHIFEHVIgpEGVLKNKTRILVTHGISYLPQV-DVIIVMSGGKISE 841
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
248-499 |
3.45e-04 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 43.61 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 248 RFPKREAKIGEIYFEindwnvfdpvVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGraygkhitgkvkkdgk 327
Cdd:PTZ00243 655 RSAKTPKMKTDDFFE----------LEPKVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLS---------------- 708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 328 ELLLKNVRQAIENGLAYVTEDRKTAGLVLIDNI-----KKNISLAKLGKLSknqvidenkeiQVAEELRRKLNIKSSSIL 402
Cdd:PTZ00243 709 QFEISEGRVWAERSIAYVPQQAWIMNATVRGNIlffdeEDAARLADAVRVS-----------QLEADLAQLGGGLETEIG 777
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 403 QKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGID--VGAKYEIYTIINKLAeeGKSIIIISSELpEILGMCDRIYVM 480
Cdd:PTZ00243 778 EKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDahVGERVVEECFLGALA--GKTRVLATHQV-HVVPRADYVVAL 854
|
250
....*....|....*....
gi 543000761 481 NEGRIVGELDQKDASQESI 499
Cdd:PTZ00243 855 GDGRVEFSGSSADFMRTSL 873
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
408-464 |
3.58e-04 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 41.37 E-value: 3.58e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLaeegkSIIIIS 464
Cdd:cd03223 92 LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKEL-----GITVIS 143
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
407-480 |
4.59e-04 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 41.97 E-value: 4.59e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVM 480
Cdd:cd03236 139 QLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYIHCL 212
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
406-439 |
4.75e-04 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 42.80 E-value: 4.75e-04
10 20 30
....*....|....*....|....*....|....
gi 543000761 406 GNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGID 439
Cdd:NF033858 135 GKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVD 168
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
276-498 |
5.35e-04 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 42.78 E-value: 5.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELaMSVFGRAYgkHIT-GKVKKDGkeLLLKNVR-QAIENGLAYVTEdrktAG 353
Cdd:PRK10789 328 HPALENVNFTLKPGQMLGICGPTGSGKSTL-LSLIQRHF--DVSeGDIRFHD--IPLTKLQlDSWRSRLAVVSQ----TP 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 354 LVLIDNIKKNISLAKLGklSKNQVIDENKEI-QVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILD 432
Cdd:PRK10789 399 FLFSDTVANNIALGRPD--ATQQEIEHVARLaSVHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLLNAEILILD 476
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 433 EPTRGIDVGAKYEiytIINKLAEEGKS-IIIISSELPEILGMCDRIYVMNEGRIVGELDQKDASQES 498
Cdd:PRK10789 477 DALSAVDGRTEHQ---ILHNLRQWGEGrTVIISAHRLSALTEASEILVMQHGHIAQRGNHDQLAQQS 540
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
274-462 |
7.40e-04 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 40.94 E-value: 7.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 274 DGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAmsvfgraygKHITGKVKKDGKELLLKN-----VRQAIENGLAYVTEd 348
Cdd:cd03231 11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLL---------RILAGLSPPLAGRVLLNGgpldfQRDSIARGLLYLGH- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 349 rkTAGLVLIDNIKKNISLAKlgklsknqviDENKEIQVAEELRR-KLNIKSSSILqktGNLSGGNQQKVVLSKWIFTDPE 427
Cdd:cd03231 81 --APGIKTTLSVLENLRFWH----------ADHSDEQVEEALARvGLNGFEDRPV---AQLSAGQQRRVALARLLLSGRP 145
|
170 180 190
....*....|....*....|....*....|....*
gi 543000761 428 VLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIII 462
Cdd:cd03231 146 LWILDEPTTALDKAGVARFAEAMAGHCARGGMVVL 180
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
400-463 |
1.45e-03 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 40.08 E-value: 1.45e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 543000761 400 SILQKTGN-LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEgKSIIII 463
Cdd:PRK10247 129 TILTKNIAeLSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVRE-QNIAVL 192
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
356-464 |
1.50e-03 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 41.38 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLAKLGKLSKN-QVIDENKEIQVAEELRRKLNIKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:PLN03073 292 NKDGVDKDAVSQRLEEIYKRlELIDAYTAEARAASILAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEP 371
|
90 100 110
....*....|....*....|....*....|
gi 543000761 435 TRGIDVGAKYEIYTIINKLAeegKSIIIIS 464
Cdd:PLN03073 372 TNHLDLHAVLWLETYLLKWP---KTFIVVS 398
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
407-497 |
1.51e-03 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 41.50 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVgakyEIYTIINK-LAEEGKS--IIIISSELPEILGmCDRIYVMNEG 483
Cdd:PLN03232 1371 NFSVGQRQLLSLARALLRRSKILVLDEATASVDV----RTDSLIQRtIREEFKSctMLVIAHRLNTIID-CDKILVLSSG 1445
|
90
....*....|....
gi 543000761 484 RIVgeldQKDASQE 497
Cdd:PLN03232 1446 QVL----EYDSPQE 1455
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
6-256 |
1.69e-03 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 40.87 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 6 LEMRNITKLFPGVKALDNVNLKVKSGEVHALVGENGAgkstlmSVLSGIYP---YGSYSGDIIFEGNVCSFKDIKDSEKI 82
Cdd:NF000106 14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GA------A**RGALPahv*GPDAGRRPWRF*TWCANRRALRRTI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 83 GIaiiHQELALIPYLSIG--ENIFLGNERAKngiINWNTTHIKATEYLNRVGLKESSQTLIKDIGVGKQQLVEIAKALAK 160
Cdd:NF000106 88 G*---HRPVR*GRRESFSgrENLYMIGR*LD---LSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 161 DVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIetmvKDATVSEdriIKGM 240
Cdd:NF000106 162 RPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVI----ADGKVDE---LKTK 234
|
250
....*....|....*.
gi 543000761 241 VGRDLVNRFPKREAKI 256
Cdd:NF000106 235 VGGRTLQIRPAHAAEL 250
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
266-486 |
1.75e-03 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 41.25 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 266 WNVFDPVVDGKKV--IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHI--TGKVKKDGkeLLLKNVRQAIENG 341
Cdd:TIGR00956 62 FRKLKKFRDTKTFdiLKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDGFHIgvEGVITYDG--ITPEEIKKHYRGD 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 342 LAYVTEDRKTAGLVlidNIKKNISLAKLGKLSKNQVIDENKEIQVAEELRRKLNIKSSSILQKT--GN-----LSGGNQQ 414
Cdd:TIGR00956 140 VVYNAETDVHFPHL---TVGETLDFAARCKTPQNRPDGVSREEYAKHIADVYMATYGLSHTRNTkvGNdfvrgVSGGERK 216
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 415 KVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKS--IIIISSELPEILGMCDRIYVMNEGRIV 486
Cdd:TIGR00956 217 RVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTtpLVAIYQCSQDAYELFDKVIVLYEGYQI 290
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
147-213 |
2.05e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 40.77 E-value: 2.05e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 147 GKQQLVEIAKALAKDVK---LLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKLnEVMKVADSI 213
Cdd:TIGR00630 833 GEAQRIKLAKELSKRSTgrtLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEHNL-DVIKTADYI 901
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
21-223 |
2.08e-03 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 39.89 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 21 LDNVNLKVKSGEVHALVGENGAGKSTLMsvLSGIYPYGSYSGDIIFEGnvcsfkdiKDSEKIGIAIIHQELALI---PYL 97
Cdd:cd03288 37 LKHVKAYIKPGQKVGICGRTGSGKSSLS--LAFFRMVDIFDGKIVIDG--------IDISKLPLHTLRSRLSIIlqdPIL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 98 SIGENIF-LGNERAKNGIINWNTTHIKATEYLNRV---GLKESSQTLIKDIGVGKQQLVEIAKALAKDVKLLILDEPTAA 173
Cdd:cd03288 107 FSGSIRFnLDPECKCTDDRLWEALEIAQLKNMVKSlpgGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATAS 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 543000761 174 LNEEdSDNLLELILELKKHGITSIIISHKLNEVMKvADSITVLRDGATIE 223
Cdd:cd03288 187 IDMA-TENILQKVVMTAFADRTVVTIAHRVSTILD-ADLVLVLSRGILVE 234
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
403-488 |
2.69e-03 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 39.58 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 403 QKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKL-AEEGKSIIIISSELPEILGMCDRIYVMN 481
Cdd:PRK10253 139 QSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELnREKGYTLAAVLHDLNQACRYASHLIALR 218
|
....*..
gi 543000761 482 EGRIVGE 488
Cdd:PRK10253 219 EGKIVAQ 225
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
408-477 |
2.94e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 40.58 E-value: 2.94e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 543000761 408 LSGGNQQKVVLSKWIFTDPE--VLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIISSElPEILGMCDRI 477
Cdd:PRK00635 477 LSGGEQERTALAKHLGAELIgiTYILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHD-EQMISLADRI 547
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
276-471 |
3.01e-03 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 39.17 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 276 KKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHITGKVKkdgkelllknvrqaienglayVTEDRKTAGLV 355
Cdd:COG2401 43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVD---------------------VPDNQFGREAS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 356 LIDNIKKNISLAklgklsknqvidenkeiQVAEELRR-KLNiKSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEP 434
Cdd:COG2401 102 LIDAIGRKGDFK-----------------DAVELLNAvGLS-DAVLWLRRFKELSTGQKFRFRLALLLAERPKLLVIDEF 163
|
170 180 190
....*....|....*....|....*....|....*..
gi 543000761 435 TRGIDVGAKYEIYTIINKLAEEGKSIIIISSELPEIL 471
Cdd:COG2401 164 CSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVI 200
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
25-439 |
3.81e-03 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 39.61 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 25 NLKVKSGEVHALVGENGAGKSTLMSVLSGIYPYgsYSGDIifegnVCSFKDIK--DSEKIGiAIIHQELAL--IPYLSIG 100
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPL--LSGER-----QSQFSHITrlSFEQLQ-KLVSDEWQRnnTDMLSPG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 101 ENIFlGNERAKngIINwntTHIKATEYLNRVGLKESSQTLI----KDIGVGKQQLVEIAKALAKDVKLLILDEPTAALNE 176
Cdd:PRK10938 95 EDDT-GRTTAE--IIQ---DEVKDPARCEQLAQQFGITALLdrrfKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 177 EDSDNLLELILELKKHGITSIIISHKLNEVMKVADSITVLRDGATIETMVKDATVSEDRIIKGMVGRDLVN-RFPKREAK 255
Cdd:PRK10938 169 ASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQQALVAQLAHSEQLEGvQLPEPDEP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 256 I-------GEIYFEINDWNVfdpVVDGKKVIKNVNLKVHRGEVVGISGLMGSGRTELAMSVFG---RAYGKHIT--GKVK 323
Cdd:PRK10938 249 SarhalpaNEPRIVLNNGVV---SYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGdhpQGYSNDLTlfGRRR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 324 KDGKELLlkNVRQAIenglAYVT-----EDRKTAGL--VLIDNIKKNISLAKlgklsknQVIDenKEIQVAEELRRKLNI 396
Cdd:PRK10938 326 GSGETIW--DIKKHI----GYVSsslhlDYRVSTSVrnVILSGFFDSIGIYQ-------AVSD--RQQKLAQQWLDILGI 390
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 543000761 397 KSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGID 439
Cdd:PRK10938 391 DKRTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLD 433
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
20-70 |
3.83e-03 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 39.03 E-value: 3.83e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 543000761 20 ALDNVNLKVKSGEVHALVGENGAGKSTLMSVLSGIYPygSYSGDIIFEGNV 70
Cdd:PRK13546 39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLS--PTVGKVDRNGEV 87
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
415-464 |
4.32e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 39.49 E-value: 4.32e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 543000761 415 KVVLSKWIFTDPEVLILDEPTRGIDvgakyeIYTII---NKLAEEGKSIIIIS 464
Cdd:PRK15064 163 RVLLAQALFSNPDILLLDEPTNNLD------INTIRwleDVLNERNSTMIIIS 209
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
279-490 |
5.58e-03 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 38.64 E-value: 5.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAygKHITGKVKKDGKELLLknvrqAIENGLayvtedrkTAGLVLID 358
Cdd:PRK13546 40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSL--SPTVGKVDRNGEVSVI-----AISAGL--------SGQLTGIE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 359 NIKknISLAKLGkLSKNQVIDENKEIQVAEELrrklnikSSSILQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGI 438
Cdd:PRK13546 105 NIE--FKMLCMG-FKRKEIKAMTPKIIEFSEL-------GEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVG 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 543000761 439 DVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDRIYVMNEGRI--VGELD 490
Cdd:PRK13546 175 DQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLkdYGELD 228
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
23-219 |
6.19e-03 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 38.70 E-value: 6.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 23 NVNLKVKSGEVHALVGENGAGKSTLMSVLSG-IYPYgsySGDIIFEGNVCSfkdikDS--------EKIGIAIIHQELAL 93
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGlTRPQ---KGRIVLNGRVLF-----DAekgiclppEKRRIGYVFQDARL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 94 IPYLSIGENIflgnerakngiinwntthikateylnRVGLKESSQTLIKDI----GV-------------GKQQLVEIAK 156
Cdd:PRK11144 88 FPHYKVRGNL--------------------------RYGMAKSMVAQFDKIvallGIeplldrypgslsgGEKQRVAIGR 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 157 ALAKDVKLLILDEPTAALN-----------EEDSDNLLelilelkkhgITSIIISHKLNEVMKVADSITVLRDG 219
Cdd:PRK11144 142 ALLTAPELLLMDEPLASLDlprkrellpylERLAREIN----------IPILYVSHSLDEILRLADRVVVLEQG 205
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
339-459 |
6.50e-03 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 38.54 E-value: 6.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 339 ENGLAYVTEDRKTAGLVLIDNIKKNISLAKLGklSKNQVIDENKEIQVAEELRRKLNIKSS---------------SIL- 402
Cdd:cd03237 33 PNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS--YKPQYIKADYEGTVRDLLSSITKDFYThpyfkteiakplqieQILd 110
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 543000761 403 QKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKS 459
Cdd:cd03237 111 REVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENNEK 167
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
407-479 |
6.84e-03 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 37.55 E-value: 6.84e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 543000761 407 NLSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEG-KSIIIISSELPEILGMCDRIYV 479
Cdd:cd03222 71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGkKTALVVEHDLAVLDYLSDRIHV 144
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
408-486 |
7.22e-03 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 39.06 E-value: 7.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 408 LSGGNQQKVVLSKWIFTDPEVLILDEPTRGIDVGAKYEIYTIINKLAEEGKSIIIIS--SELPEILGMCDRIYVMNEGRI 485
Cdd:PLN03140 337 ISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSllQPAPETFDLFDDIILLSEGQI 416
|
.
gi 543000761 486 V 486
Cdd:PLN03140 417 V 417
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
147-213 |
8.98e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 36.95 E-value: 8.98e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 543000761 147 GKQQLVEIAKALA----KDVKLLILDEPTAALNEEDSDNLLELILELKKHGITSIIISHKlNEVMKVADSI 213
Cdd:cd03227 81 GEKELSALALILAlaslKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHL-PELAELADKL 150
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
279-476 |
9.13e-03 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 38.72 E-value: 9.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 279 IKNVNLKVHRGEVVGISGLMGSGRTELAMSVFGRAYGKHitGKVKKDGKELLLknvrqAIENGLayvteDRKTAGLvlid 358
Cdd:PRK13545 40 LNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNK--GTVDIKGSAALI-----AISSGL-----NGQLTGI---- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 543000761 359 nikKNISLAKLGK-LSKNQVIDENKEIQVAEELRRKLNiksssilQKTGNLSGGNQQKVVLSKWIFTDPEVLILDEPTRG 437
Cdd:PRK13545 104 ---ENIELKGLMMgLTKEKIKEIIPEIIEFADIGKFIY-------QPVKTYSSGMKSRLGFAISVHINPDILVIDEALSV 173
|
170 180 190
....*....|....*....|....*....|....*....
gi 543000761 438 IDVGAKYEIYTIINKLAEEGKSIIIISSELPEILGMCDR 476
Cdd:PRK13545 174 GDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTK 212
|
|
| |
