|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
36-855 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1390.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 36 EGDQIFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDS 115
Cdd:PRK05560 1 EGDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 116 AIYDAMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARF 195
Cdd:PRK05560 81 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 196 PNLLVNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEacieRIQGPDFPNGATITGRKGIEEAYRTGRGS 275
Cdd:PRK05560 161 PNLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELME----IIPGPDFPTGGIILGRSGIREAYRTGRGS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 276 ITQRAVVKTEEINGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDETSgKTGQRLVLTLKRDAVAKVVLNNL 355
Cdd:PRK05560 237 IVMRAKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 356 YKQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRS 435
Cdd:PRK05560 316 YKHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRAS 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 436 PDVDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIVEKYG 515
Cdd:PRK05560 396 PTPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFG 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 516 DERRTQIVPFDGDVSVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTTTTHKWLLFFT 595
Cdd:PRK05560 476 DPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFT 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 596 NFGRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAFDSNRSAGLIAI 675
Cdd:PRK05560 556 NRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAI 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 676 NLREfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDVAHPD-T 754
Cdd:PRK05560 636 NLDE---------GDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVREDsQ 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 755 FVFTVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPNDRGHLVGAAIVEETDEVFVLMEKGKVVRSSVAGVPSKGRDTMGV 834
Cdd:PRK05560 705 EILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGV 784
|
810 820
....*....|....*....|.
gi 514222660 835 VFAKPDQKDSIILVNVFKESE 855
Cdd:PRK05560 785 RLIRLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
33-846 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1328.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 33 DEDEGDQIFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPH 112
Cdd:COG0188 3 DPPPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 113 GDSAIYDAMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILP 192
Cdd:COG0188 83 GDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 193 ARFPNLLVNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEacieRIQGPDFPNGATITGRKGIEEAYRTG 272
Cdd:COG0188 163 ARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELME----YIPGPDFPTGGIIVGREGIREAYETG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 273 RGSITQRAVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVV 351
Cdd:COG0188 239 RGSIRVRAKAEIEELkRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDE-SDRDGMRIVIELKRDANPEVV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 352 LNNLYKQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIAT 431
Cdd:COG0188 318 LNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAI 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 432 IRRSPDVDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIV 511
Cdd:COG0188 398 IRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIK 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 512 EKYGDERRTQIVPFDGDVSVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTTTTHKWL 591
Cdd:COG0188 478 KKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTL 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 592 LFFTNFGRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAFDSNRSAG 671
Cdd:COG0188 558 LFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 672 LIAINLREfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDVAH 751
Cdd:COG0188 638 IIAINLKE---------GDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVVD 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 752 PDTFVFTVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPNDRGHLVGAAIVEETDEVFVLMEKGKVVRSSVAGVPSKGRDT 831
Cdd:COG0188 707 EEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNT 786
|
810
....*....|....*
gi 514222660 832 MGVVFAKPDQKDSII 846
Cdd:COG0188 787 QGVRLIRLDEGDKVV 801
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
40-853 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1103.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 40 IFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYD 119
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 120 AMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLL 199
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 200 VNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEAcierIQGPDFPNGATITGRKGIEEAYRTGRGSITQR 279
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEV----IKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 280 AVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVVLNNLYKQ 358
Cdd:TIGR01063 237 ARAEIEEDsKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 359 TQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSPDV 438
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 439 DEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIVEKYGDER 518
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 519 RTQIVPFDGDV-SVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTTTTHKWLLFFTNF 597
Cdd:TIGR01063 476 RTEIVYDESEDiDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 598 GRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAFDSNRSAGLIAINL 677
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 678 REfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDVAHPDTFVF 757
Cdd:TIGR01063 636 DD---------GDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 758 TVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPNDRGHLVGAAIVEETDEVFVLMEKGKVVRSSVAGVPSKGRDTMGVVFA 837
Cdd:TIGR01063 705 IVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLI 784
|
810
....*....|....*.
gi 514222660 838 KPDQKDSIILVNVFKE 853
Cdd:TIGR01063 785 RLDEDDKLVSVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
62-510 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 632.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 62 VGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMVRLVQPWNMRYPLILGQGNF 141
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 142 GSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLLVNGSAGIAVGMATNIPPHNLRE 221
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 222 VASAVQWLLTNPEATKEELLeaciERIQGPDFPNGATITGRKGIEEAYRTGRGSITQRAVVKTEEINGRLALVVTELPYQ 301
Cdd:cd00187 161 VIDALRALIDNPEASIDELM----EIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 302 VNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVVLNNLYKQTQLQENFSANMLAIVND-VPRTL 380
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPNgRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 381 SIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSpdvDEARTALIALL---DIDEIQAN 457
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 514222660 458 AILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAI 510
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
43-500 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 591.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 43 VDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMV 122
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 123 RLVQPWNMRYPLILGQGNFGS-AGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLLVN 201
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSrLDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 202 GSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLeaciERIQGPDFPNGATITGRKgieeayrtgrgSITQRAV 281
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELM----MIPWGPDFPTGGEIVGPG-----------KYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 282 VKTEEINgrlALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDETSGKTGQRLVLTLKRDAVAKVVLNNLYKQTQL 361
Cdd:smart00434 226 IEIEDDN---TIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 362 QENFSANMLAIVND-VPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQ-IHIYRGYLKALDALDEVIATIRRSPD-V 438
Cdd:smart00434 303 QTTFSINMLALFDNgRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEAErLHILEGLFIALSIIDEIIVLIRSSKDlA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514222660 439 DEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQR 500
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
64-508 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 576.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 64 RALPDVRDGLKPVHRRIVYGMYDGgYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMVRLVQPWNMRYPLILGQGNFGS 143
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 144 A-GDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLLVNGSAGIAVGMATNIPPHNLREV 222
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 223 ASAVQWLLTNPEATkeELLeaciERIQGPDFPNGATITGRKGIEEAYRTGRGSITQRAVVKTEEingRLALVVTELPYQV 302
Cdd:pfam00521 160 IDALIALLDGPEAT--LLM----KYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 303 NPDNLARKIAELVKAGRLQGIADITDETSgkTGQRLVLTLKRDAVAKVVLNNLYKQTQLQENFSANMLAIVNDVPRTLSI 382
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 383 DSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSPDVDEARTALIAllDIDEIQANAILAL 462
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 514222660 463 QLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELE 508
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
43-154 |
1.59e-65 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 239.24 E-value: 1.59e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 43 VDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMV 122
Cdd:NF038098 5 VDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTLV 84
|
90 100 110
....*....|....*....|....*....|..
gi 514222660 123 RLVQPWNMRYPLILGQGNFGSAGDDGAAASRY 154
Cdd:NF038098 85 RMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
36-855 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1390.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 36 EGDQIFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDS 115
Cdd:PRK05560 1 EGDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 116 AIYDAMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARF 195
Cdd:PRK05560 81 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 196 PNLLVNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEacieRIQGPDFPNGATITGRKGIEEAYRTGRGS 275
Cdd:PRK05560 161 PNLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELME----IIPGPDFPTGGIILGRSGIREAYRTGRGS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 276 ITQRAVVKTEEINGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDETSgKTGQRLVLTLKRDAVAKVVLNNL 355
Cdd:PRK05560 237 IVMRAKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 356 YKQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRS 435
Cdd:PRK05560 316 YKHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRAS 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 436 PDVDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIVEKYG 515
Cdd:PRK05560 396 PTPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFG 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 516 DERRTQIVPFDGDVSVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTTTTHKWLLFFT 595
Cdd:PRK05560 476 DPRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFT 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 596 NFGRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAFDSNRSAGLIAI 675
Cdd:PRK05560 556 NRGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAI 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 676 NLREfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDVAHPD-T 754
Cdd:PRK05560 636 NLDE---------GDELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVREDsQ 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 755 FVFTVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPNDRGHLVGAAIVEETDEVFVLMEKGKVVRSSVAGVPSKGRDTMGV 834
Cdd:PRK05560 705 EILTVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGV 784
|
810 820
....*....|....*....|.
gi 514222660 835 VFAKPDQKDSIILVNVFKESE 855
Cdd:PRK05560 785 RLIRLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
33-846 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1328.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 33 DEDEGDQIFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPH 112
Cdd:COG0188 3 DPPPAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 113 GDSAIYDAMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILP 192
Cdd:COG0188 83 GDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 193 ARFPNLLVNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEacieRIQGPDFPNGATITGRKGIEEAYRTG 272
Cdd:COG0188 163 ARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELME----YIPGPDFPTGGIIVGREGIREAYETG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 273 RGSITQRAVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVV 351
Cdd:COG0188 239 RGSIRVRAKAEIEELkRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDE-SDRDGMRIVIELKRDANPEVV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 352 LNNLYKQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIAT 431
Cdd:COG0188 318 LNQLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAI 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 432 IRRSPDVDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIV 511
Cdd:COG0188 398 IRASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIK 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 512 EKYGDERRTQIVPFDGDVSVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTTTTHKWL 591
Cdd:COG0188 478 KKYGDERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTL 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 592 LFFTNFGRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAFDSNRSAG 671
Cdd:COG0188 558 LFFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 672 LIAINLREfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDVAH 751
Cdd:COG0188 638 IIAINLKE---------GDELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVVD 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 752 PDTFVFTVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPNDRGHLVGAAIVEETDEVFVLMEKGKVVRSSVAGVPSKGRDT 831
Cdd:COG0188 707 EEDDLLTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNT 786
|
810
....*....|....*
gi 514222660 832 MGVVFAKPDQKDSII 846
Cdd:COG0188 787 QGVRLIRLDEGDKVV 801
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
40-853 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1103.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 40 IFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYD 119
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 120 AMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLL 199
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 200 VNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEAcierIQGPDFPNGATITGRKGIEEAYRTGRGSITQR 279
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEV----IKGPDFPTGGIILGRSGIRSAYETGRGSIVIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 280 AVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVVLNNLYKQ 358
Cdd:TIGR01063 237 ARAEIEEDsKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 359 TQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSPDV 438
Cdd:TIGR01063 316 TQLQVSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 439 DEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIVEKYGDER 518
Cdd:TIGR01063 396 EEAKTRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 519 RTQIVPFDGDV-SVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTTTTHKWLLFFTNF 597
Cdd:TIGR01063 476 RTEIVYDESEDiDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNR 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 598 GRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAFDSNRSAGLIAINL 677
Cdd:TIGR01063 556 GKVYWLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 678 REfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDVAHPDTFVF 757
Cdd:TIGR01063 636 DD---------GDELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEESYLL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 758 TVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPNDRGHLVGAAIVEETDEVFVLMEKGKVVRSSVAGVPSKGRDTMGVVFA 837
Cdd:TIGR01063 705 IVTENGYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLI 784
|
810
....*....|....*.
gi 514222660 838 KPDQKDSIILVNVFKE 853
Cdd:TIGR01063 785 RLDEDDKLVSVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
33-793 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 870.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 33 DEDEGDQIFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPH 112
Cdd:PRK05561 3 DMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 113 GDSAIYDAMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILP 192
Cdd:PRK05561 83 GDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 193 ARFPNLLVNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEAcierIQGPDFPNGATI-TGRKGIEEAYRT 271
Cdd:PRK05561 163 ARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEF----VPGPDFPTGGEIiTGRDGIRKAYET 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 272 GRGSITQRAVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDETSGKTGQRLVLTLKRDAV-AK 349
Cdd:PRK05561 239 GRGSIRVRARWEIEDLaGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNRVdPE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 350 VVLNNLYKQTQLQENFSANMLAIVND-VPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEV 428
Cdd:PRK05561 319 ALMNHLFATTDLESSYRVNMNAIGLDgRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 429 IATIRRSpdvDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELE 508
Cdd:PRK05561 399 IRIIRES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 509 AIVEKYGDERRTQIV--PFDGDVSVEDLIPEEDMVVTITRGGWVKRTKTDEYRAQkrggkgvrGASLREND-VVDHFFTT 585
Cdd:PRK05561 476 ADAKKFGDPRRTPIEeaEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS--------GLSFKEGDsLLFAFEAR 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 586 TTHKwLLFFTNFGRVYRIKGYELPEAPRDskGQHIANLLEFQPDETIRSVLViggYDEAEYLVLATKHGIVKKTAMSAFD 665
Cdd:PRK05561 548 TTDK-LLLFTSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVLA---FDPDQKLLLASSAGYGFVVTLEDLV 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 666 SNRSAGLIAINLrefegPDGslvtDELVAARAVNSDDHLLLVSKNGQSVRFPASDdvLRPMGRvTGGVTGMKFRGDDE-L 744
Cdd:PRK05561 622 ARTRAGKAVINL-----KDG----DEVLPPVPVEDDDHLAAITSNGRLLVFPLSE--LPELGK-GKGVKLINLPKDDDgL 689
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 514222660 745 LAMDVAHPDTFVFTVTdsgfakrssideyrvQGRGGLGIKVAKLPNDRG 793
Cdd:PRK05561 690 VDLRVLNPEDGLVLLT---------------AGKRKLKLKPSELEKYRG 723
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
62-510 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 632.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 62 VGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMVRLVQPWNMRYPLILGQGNF 141
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 142 GSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLLVNGSAGIAVGMATNIPPHNLRE 221
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 222 VASAVQWLLTNPEATKEELLeaciERIQGPDFPNGATITGRKGIEEAYRTGRGSITQRAVVKTEEINGRLALVVTELPYQ 301
Cdd:cd00187 161 VIDALRALIDNPEASIDELM----EIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 302 VNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVVLNNLYKQTQLQENFSANMLAIVND-VPRTL 380
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDPNgRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 381 SIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSpdvDEARTALIALL---DIDEIQAN 457
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 514222660 458 AILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAI 510
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
43-500 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 591.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 43 VDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMV 122
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 123 RLVQPWNMRYPLILGQGNFGS-AGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLLVN 201
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSrLDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 202 GSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLeaciERIQGPDFPNGATITGRKgieeayrtgrgSITQRAV 281
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELM----MIPWGPDFPTGGEIVGPG-----------KYVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 282 VKTEEINgrlALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDETSGKTGQRLVLTLKRDAVAKVVLNNLYKQTQL 361
Cdd:smart00434 226 IEIEDDN---TIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 362 QENFSANMLAIVND-VPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQ-IHIYRGYLKALDALDEVIATIRRSPD-V 438
Cdd:smart00434 303 QTTFSINMLALFDNgRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEAErLHILEGLFIALSIIDEIIVLIRSSKDlA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 514222660 439 DEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQR 500
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
40-785 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 588.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 40 IFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYD 119
Cdd:PRK13979 13 IIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 120 AMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLL 199
Cdd:PRK13979 93 AMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 200 VNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLeaciERIQGPDFPNGATITGRKGIEEAYRTGRGSITQR 279
Cdd:PRK13979 173 VNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELM----NYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLR 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 280 AVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGR----LQGIADITDEtSGKTGQRLVLTLKRDA---VAKVV 351
Cdd:PRK13979 249 AKTKIEKLeNGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDE-SDRNGIRAVIEFKKSAdedVAEKV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 352 LNNLYKQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIAT 431
Cdd:PRK13979 328 LKYLYKKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKT 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 432 IRRSPDVDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIV 511
Cdd:PRK13979 408 IRSSKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVK 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 512 EKYGDERRTQIVPFDGD--VSVEDLIPEEDMVVTITRGGWVKRTKTDEYraqKRGGKGVRGASLRENDVVDHFFTTTTHK 589
Cdd:PRK13979 488 EKYGDERRTSIIEDDEKakIDVEELIVVEDVVITLSNEGFIKRIPLKSY---NRSNSNVEDIEYREGDFNKFLIQSNTKD 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 590 WLLFFTNFGRVYRIKGYELPEAPRDSKGQHIANL-----LEfqpDETIRSVLVIGGYDEAEYLVLATKHGIVKKTAMSAF 664
Cdd:PRK13979 565 TLLIFTDKGNMYQIKGINIPEFKWKEKGERLDEIikgidLE---SEKIIEAYSIEDFTPQKDFIFITDSGGIKKTSLDKF 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 665 DSNRSAgLIAINLREfegpdgslvTDELVAARAVN---SDDHLLLVSKNGqsVRFPASDDVLRPMGRVTGGVTGMKFRGD 741
Cdd:PRK13979 642 VTNYTK-LMALKLKK---------GEKLIKVKLVDrtrEEKFIKIKTKKG--LSFTVEEPELEPVDRNIIGYQLFDLLPN 709
|
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 514222660 742 DELLAMD-VAHPDTFVFTVtdsGFAKRSSIDEYRVQGRGGLGIKV 785
Cdd:PRK13979 710 DSIKKVDfCDNYEYKEFYV---NINKKGIIKISDKDNKSSISVFT 751
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
64-508 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 576.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 64 RALPDVRDGLKPVHRRIVYGMYDGgYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMVRLVQPWNMRYPLILGQGNFGS 143
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 144 A-GDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLLVNGSAGIAVGMATNIPPHNLREV 222
Cdd:pfam00521 80 RiDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 223 ASAVQWLLTNPEATkeELLeaciERIQGPDFPNGATITGRKGIEEAYRTGRGSITQRAVVKTEEingRLALVVTELPYQV 302
Cdd:pfam00521 160 IDALIALLDGPEAT--LLM----KYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 303 NPDNLARKIAELVKAGRLQGIADITDETSgkTGQRLVLTLKRDAVAKVVLNNLYKQTQLQENFSANMLAIVNDVPRTLSI 382
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 383 DSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSPDVDEARTALIAllDIDEIQANAILAL 462
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 514222660 463 QLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELE 508
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
40-790 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 567.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 40 IFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYD 119
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 120 AMVRLVQPWNMRYPLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNLL 199
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 200 VNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEACieriQGPDFPNGATITGRKGIEEAYRTGRGSITQR 279
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIV----KGPDFPTGGIIQGEDGISKAYETGKGKFIIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 280 AVVKTEEI-NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDEtSGKTGQRLVLTLKRDAVAKVVLNNLYKQ 358
Cdd:TIGR01061 237 AKIEIEVNkNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDE-SDRNGIRIIIELKKDANAEKILNFLFKH 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 359 TQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRSPDV 438
Cdd:TIGR01061 316 TDLQINYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDK 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 439 DEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIVEKYGDER 518
Cdd:TIGR01061 396 SDAKENLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 519 RTQIVPFDGDVSVED--LIPEEDMVVTITRGGWVKRTKTDEYRAQKRGGKGvrgasLRENDVVDHFFTTTTHKWLLFFTN 596
Cdd:TIGR01061 476 RSQIEDFINQIKINEseLIENEDYYVLITKAGYIKRTSNRSFASSKYTDFG-----SKDDDILFAQTIANTTDQILIFTS 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 597 FGRVYRIKGYELPEAPRDSKGQHIANLLEFQPDETIRSVLVIGGYD-EAEYLVLATKHGIVKKTAMSAFDSNR-SAGLIA 674
Cdd:TIGR01061 551 LGNIINIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDvDQPILVLASKLGMVKRIELTELNIKRnSKATLC 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 675 INLREfegpdgslvTDELVAARAVNSDDHLLLVSKNGQSVRFpaSDDVLRPMGRVTGGVTGMKFRGDDELLAMDVAHPDT 754
Cdd:TIGR01061 631 IKLKD---------KDHLISAFLQQKDKLICLVSDLGYALVF--HTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFEANE 699
|
730 740 750
....*....|....*....|....*....|....*.
gi 514222660 755 FVFTVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLPN 790
Cdd:TIGR01061 700 SLVLLTQRGSVKRLSISELVVTSRAATGKKLLPLKK 735
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
40-720 |
4.00e-165 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 498.28 E-value: 4.00e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 40 IFQVDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYD 119
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 120 AMVRLVQPWNMRYPLILGQGNFGSAGD-DGAAASRYTECKMSPLALELVRDINEDTVDMTGNYDNTVDEPVILPARFPNL 198
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 199 LVNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATKEELLEAcierIQGPDFPNGA-TITGRKGIEEAYRTGRGSIT 277
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNI----VQGPDFPTEAeIIDKAEEIRKIYETGRGSFR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 278 QRAVVKTEEingrLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDETSGKTGQRLVLTLKRDAV-AKVVLNNLY 356
Cdd:TIGR01062 237 MRARWKKED----GQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVdPDIVMEHLF 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 357 KQTQLQENFSANMLAI-VNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYRGYLKALDALDEVIATIRRS 435
Cdd:TIGR01062 313 ATTDLEKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREE 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 436 pdvDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRLAALILEYEEILGSEQRQREIVSEELEAIVEKYG 515
Cdd:TIGR01062 393 ---DEPKTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYG 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 516 DERRTQIVPFD--GDVSVEDLIPEEDMVVTITRGGWVKRTKTDEYRAqkrggkgvRGASLRENDVVDHFFTTTTHKWLLF 593
Cdd:TIGR01062 470 LARRSSLEEREeaKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDL--------STLKYKAGDSEKAIIEGKSNQKVVF 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 594 FTNFGRVYRIKGYELPEAprDSKGQHIANLLEFQPDETIRSVLViggYDEAEYLVLATKHG---IVKKTAMSAfdSNRsA 670
Cdd:TIGR01062 542 IDSTGRSYALDPDNLPSA--RGQGEPLTGKLLLPIGATITNILM---YSPNQLLLMASDAGygfLCNFNDLIA--RNK-A 613
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|
gi 514222660 671 GLIAINLrefegPDGSLVTDELVaarAVNSDDHLLLVSKNGQSVRFPASD 720
Cdd:TIGR01062 614 GKALINL-----PENASVIAPLP---VNGDSDMIAAITEAGRMLVFPIDD 655
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
44-522 |
1.59e-68 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 239.99 E-value: 1.59e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 44 DLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYG---MYDGgyrperSFSKCAKVVGEVMgNYHPHGDSAIYDA 120
Cdd:PRK09631 3 DIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSlfeMHDG------KFHKVANVVGNTM-KYHPHGDASIYEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 121 MVRLVqpwNMRYpLILGQGNFGS--AGDDgAAASRYTECKMSPLALELVrdINEDTVDMTGNYDNTVDEPVILPARFPNL 198
Cdd:PRK09631 76 LVNLA---NKDL-FIDKQGNFGNlfTGDP-ASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVI 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 199 LVNGSAGIAVGMATNIPPHNLREVASAVqwlltnpeatKEELLEACIERIqgPDFPNGatitgrkGIEEA--YRTGRGSI 276
Cdd:PRK09631 149 LIQGAEGIAVGMATKILPHNFNEILQAV----------KSELLGESFALY--PDFPTG-------GIVDVseYADGNGKV 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 277 TQRAvvKTEEINGRlALVVTELPYQVNPDNLARKIAELVKAGRLQgIADITDETSGKTgqRLVLTLKRDAVAKVVLNNLY 356
Cdd:PRK09631 210 LVRA--KIETKDEK-TIVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTAENV--EIEIKLPRGVYASEVIEALY 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 357 KQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIH------------IYRgYLKALDA 424
Cdd:PRK09631 284 AYTDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIFaktleqifieerIYK-RIETISS 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 425 LDEVIATIRRSpdVDEARTALIALLDIDEIQanAILALQLRRLAALERQKITEEhdrLAALILEYEEILGSEQRQREIVS 504
Cdd:PRK09631 363 EEDVISIVLSE--LKPFKEELSRDVTEEDIE--NLLKIPIRRISLFDIDKNQKE---IRILNKELKSVEKNLKSIKGYAI 435
|
490 500
....*....|....*....|
gi 514222660 505 EELEAIVEKYGDE--RRTQI 522
Cdd:PRK09631 436 NFIDKLLAKYSKEypRKTEI 455
|
|
| GyrA_w_intein |
NF038098 |
intein-containing DNA gyrase subunit A; |
43-154 |
1.59e-65 |
|
intein-containing DNA gyrase subunit A;
Pssm-ID: 411680 [Multi-domain] Cd Length: 1232 Bit Score: 239.24 E-value: 1.59e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 43 VDLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEVMGNYHPHGDSAIYDAMV 122
Cdd:NF038098 5 VDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSYVKCARVVAETMGNYHPHGDSSIYDTLV 84
|
90 100 110
....*....|....*....|....*....|..
gi 514222660 123 RLVQPWNMRYPLILGQGNFGSAGDDGAAASRY 154
Cdd:NF038098 85 RMAQPWSLRYPLVDGQGNFGSPGNDPAAAMRY 116
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
53-526 |
1.13e-58 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 216.02 E-value: 1.13e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 53 YLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMY---DGGYrpersfSKCAKVVGEVMgNYHPHGDSAIYDAMVRLVQpwn 129
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKemdDGRY------NKVANVVGHTM-QYHPHGDASIGDALVQLGQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 130 mRYPLILGQGNFGS--AGDdGAAASRYTECKMSPLALELVrdINEDTVDMTGNYDNTVDEPVILPARFPNLLVNGSAGIA 207
Cdd:PRK12758 101 -KDLLIDTQGNWGNilTGD-GAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 208 VGMATNIPPHNLRevasavqwlltnpeatkeELLEACIERIQG------PDFPNGATI------TGRKGieeayrtgrGS 275
Cdd:PRK12758 177 VGLSTKILPHNFN------------------ELIDASIAYLKGkefklyPDFPTGGIIdvsnynDGERG---------GR 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 276 ITQRAvvKTEEINGRlALVVTELPYQVNPDNLARKIAELVKAGRLQgIADITDETSGKTgqRLVLTLKRDAVAKVVLNNL 355
Cdd:PRK12758 230 VRVRA--KIEKLDKK-TLVITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTAADV--EILVHLAPGVSPDKTIDAL 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 356 YKQTQLQENFSANMLAIVNDVPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIH------------IYRGYLKALD 423
Cdd:PRK12758 304 YAFTDCEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHfaslekifieerIYKEIEEAET 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 424 aLDEVIATIrrspdvDEARTALIALLdIDEIQANAILAL---QLRRLAALERQKITEEHDRLAAlilEYEEIlgsEQRQR 500
Cdd:PRK12758 384 -WEAVIEAI------DKGLEPFKKQF-IREVTEDDIVRLteiKIKRISKFDSDKADELIARLEA---EIAEV---KHHLA 449
|
490 500 510
....*....|....*....|....*....|.
gi 514222660 501 EIVS---EELEAIVEKYGD--ERRTQIVPFD 526
Cdd:PRK12758 450 HLTDyaiAYFTNLKKKYGKgrERKTEIRNFD 480
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
44-525 |
3.35e-48 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 178.55 E-value: 3.35e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 44 DLNKEMQKSYLDYAMSVIVGRALPDVRDGLKPVHRRIVYGMY--DGGyrperSFSKCAKVVGEVMGnYHPHGDSAIYDAM 121
Cdd:PRK09630 3 DVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLFrmDDG-----KMHKVANIAGRTMA-LHPHGDAPIVEAL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 122 VRLVqpwNMRYpLILGQGNFGS--AGDDGAAAsRYTECKMSPLALELVrdINEDTVDMTGNYDNTVDEPVILPARFPNLL 199
Cdd:PRK09630 77 VVLA---NKGY-LIDTQGNFGNplTGDPHAAA-RYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 200 VNGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATkeeLLeacieriqgPDFPNGATITGRKgieeaYRTGRGSITQR 279
Cdd:PRK09630 150 LHGVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFT---LL---------PDFPSGGTMDASE-----YQDGLGSITLR 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 280 AVVKTeeINGRlALVVTELPYQVNPDNLARKIAELVKAGRLQgIADITDETSGKTgqRLVLTLKRDAVAKVVLNNLYKQT 359
Cdd:PRK09630 213 ASIDI--INDK-TLLIKEICPSTTTETLIRSIENAAKRGIIK-IDSIQDFSTDLP--HIEIKLPKGIYAKDLLRPLFTHT 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 360 QLQENFSANMLAIVNDVPRTLSIDSFVREWTKhQIDVIVRRTRFRLRKAEEQIHIYRG--YL----KALDALDEVIATIR 433
Cdd:PRK09630 287 ECQVILTSRPTAIYQNKPVETSISEILRLHTE-TLQGYLKKELLILEDSLSREHYHKTleYIfikhKLYDTVREMLSKRK 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 434 RSPDVDEARTALIALLD--IDEI------QANAILA-LQLRRLAALERQKITEEhdrLAALILEYEEILGSEQRQREIVS 504
Cdd:PRK09630 366 TSPSSSDLHNAVLEALTpfLDTLptpvdkQATAQLAsLTIKKILCFNENSYTKE---LACIEKKQAAVQKDLSQLKKYTV 442
|
490 500
....*....|....*....|...
gi 514222660 505 EELEAIVEKYGD--ERRTQIVPF 525
Cdd:PRK09630 443 KYLKGLLETYGQlgHRKTQIAKF 465
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
54-482 |
5.57e-46 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 171.01 E-value: 5.57e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 54 LDYAMSVIVGRALPDVRDGLKPVHRRIVYGMYDGGYRPERSFSKCAKVVGEV-MGNYHpHGDSAIYDAMVRLVQPWNMRY 132
Cdd:PHA02592 17 LEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVaDLGYH-HGETSAQDAGALMANTWNNNI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 133 PLILGQGNFGSAGDDGAAASRYTECKMSPLALELVRDInedtvdmtgNYDNTVDEPVILPARF-----PNLLVNGSAGIA 207
Cdd:PHA02592 96 PLLDGQGNFGSRLVQKAAAARYIFARVHDNFRKIYKDE---------DLAPVHEDPEHIPPAFylpiiPMVLLNGVSGIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 208 VGMATNIPPHNLREVASAVQWLLTNPEATKEElleacieriqgPDFPngatitGRKGieEAYRTGRGSITQRAvvkTEEI 287
Cdd:PHA02592 167 TGYATNILPHSPKSVIKAVLAALNGKDITEPK-----------VQFP------EFKG--EVVEIEPGSYEIRG---TYEL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 288 NGRLALVVTELPYQVNPDNLARKIAELVKAGRLQGIADITDEtsgktGQRLVLTLKRDAVAKVVLNNLYKQTQLQENFSA 367
Cdd:PHA02592 225 NGKTKLHITEIPVKYDRETYVAVLDPLEEKGKIVSYDDCTED-----GFRFKVTLKREENEEATHEKIMKDFGLIERVSQ 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 368 NMLAI-------VNDVPRTLsidsfVREWTKHQIDVIVRRTRFRLRKAEEQIHiyrgylKALDA---LDEVIATIRRSPD 437
Cdd:PHA02592 300 NITVInengklkVYENAEDL-----IRDFVEIRKTYVQKRIQYEIKETEEAFD------LALAKaefIKRVIAGEIVLQG 368
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 514222660 438 -VDEARTALIALLDIDEIQANAILALQLRRLAALERQKITEEHDRL 482
Cdd:PHA02592 369 kTRSELTEELSDNKDFGEYADKLVAMNIYSMTSDEREKLQKEAEEL 414
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
64-416 |
8.60e-20 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 95.16 E-value: 8.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 64 RALPDVRDGLKPVHRRIVYGMYdggyrpERSFSKCAKV------VGEvMGNYHpHGDSAIYDAMVRLVQPW------NMR 131
Cdd:PLN03128 673 RSIPSMVDGLKPSQRKVLFACF------KRNLKSEIKVaqlsgyVAE-HSAYH-HGEASLASTIIGMAQDFvgsnniNLL 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 132 YPlilgQGNFGS---AGDDgAAASRYTECKMSPLALELvrdINEDTvDMTGNYDNtVDEPVILPARF----PNLLVNGSA 204
Cdd:PLN03128 745 TP----SGQFGTrlqGGKD-AASARYIFTRLSPITRAL---FPKDD-DVLLNYLN-EDGQSIEPEWYcpiiPMVLVNGSE 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 205 GIAVGMATNIPPHNLREVASAVQWLLtnpeatKEELLEacieriqgPDFPNGATITGRkgIEEAYRTGRGSITQRAVVkt 284
Cdd:PLN03128 815 GIGTGWSTFIPNYNPRDIIANIRRLL------RGEELE--------PMHPWYRGFKGT--ITEVSTSRSGSYTVTGII-- 876
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 285 eEINGRLALVVTELPYQVNPDNLaRKIAELVKAGRLQGIADITD--ETSGKTGQRLVLTLKRDAVAKVVLNNLYKQTQLQ 362
Cdd:PLN03128 877 -EQIGDTTIRITELPVRKWTQDY-KEFLEALLTGTKKKEPEIKDfkENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLS 954
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 514222660 363 ENFS-ANMLAIVND--VPRTLSIDSFVREWTKHQIDVIVRRTRFRLRKAEEQIHIYR 416
Cdd:PLN03128 955 TTIStSNMHLFDKDgkIKKYDSPEDILEEFFHLRLDLYVKRKEVLLENLEYELKKLD 1011
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
64-237 |
5.79e-15 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 79.71 E-value: 5.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 64 RALPDVRDGLKPVHRRIVYGMYdggyrpERSFSKCAKV------VGEVMGnYHpHGDSAIYDAMVRLVQPW----NMryP 133
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACF------KRNLKNEIKVaqlsgyVSEHSA-YH-HGEQSLQQTIVGMAQNFvgsnNI--N 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 134 LILGQGNFGS---AGDDGAAAsRYTECKMSPLAlelvRDI--NEDtvDMTGNY---DNTVDEP-----VIlparfPNLLV 200
Cdd:PTZ00108 750 LLYPCGQFGSrlqGGKDHAAA-RYIFTKLSKIT----RYIfpEED--DPILDYledDGQSVEPfyyvpII-----PMVLV 817
|
170 180 190
....*....|....*....|....*....|....*..
gi 514222660 201 NGSAGIAVGMATNIPPHNLREVASAVQWLLTNPEATK 237
Cdd:PTZ00108 818 NGAEGIGTGFSTSIPNYNPLDIIDNLRRRLNGEEVRP 854
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
64-299 |
1.34e-12 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 72.20 E-value: 1.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 64 RALPDVRDGLKPVHRRIVYGMYDGGYRPErsfSKCAKVVGEV--MGNYHpHGDSAIYDAMVRLVQPW----NMRypLILG 137
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSFKRNFVKE---AKVAQLSGYVseHSAYH-HGEQSLASTIIGMAQDFvgsnNIN--LLLP 771
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 138 QGNFG--SAGDDGAAASRYTECKMSPLALELVRDINEDTVDMTgNYDNTVDEPVILPARFPNLLVNGSAGIAVGMATNIP 215
Cdd:PLN03237 772 NGQFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFIP 850
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 216 PHNLREVASAVQWLLtNPEatkeelleaCIERiqgpdfpngatitgrkgIEEAYRTGRGSITQRAVVKTE---EINGRL- 291
Cdd:PLN03237 851 NYNPRDIVANIRRLL-NGE---------SMEP-----------------MHPWYRGFKGTIEKTASKEGGctyTITGLYe 903
|
250
....*....|...
gi 514222660 292 -----ALVVTELP 299
Cdd:PLN03237 904 evdetTLRITELP 916
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
539-585 |
1.05e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 57.50 E-value: 1.05e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 514222660 539 DMVVTITRGGWVKRTKTDEYRAQKRGGKGVRGASLRENDVVDHFFTT 585
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
756-802 |
5.87e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 52.49 E-value: 5.87e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 514222660 756 VFTVTDSGFAKRSSIDEYRVQGRGGLGIKVAKLpNDRGHLVGAAIVE 802
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINL-KEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
702-749 |
1.31e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.33 E-value: 1.31e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 514222660 702 DHLLLVSKNGQSVRFPASDdvLRPMGRVTGGVTGMKFRGDDELLAMDV 749
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSE--IREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
589-638 |
3.29e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 50.18 E-value: 3.29e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 514222660 589 KWLLFFTNFGRVYRIKGYELPEAPRDSKGQHIANLLEfqpDETIRSVLVI 638
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKE---GDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
645-699 |
3.21e-04 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 39.01 E-value: 3.21e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 514222660 645 EYLVLATKHGIVKKTAMSAF-DSNRSA-GLIAINLREfegpdgslvTDELVAARAVN 699
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIrEQGRGAkGVKGINLKE---------GDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
805-852 |
4.97e-03 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 35.93 E-value: 4.97e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 514222660 805 DEVFVLMEKGKVVRSSVAGVPSKGRDTMGVVFAKPDQKDSIILVNVFK 852
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
381-509 |
8.32e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.90 E-value: 8.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 514222660 381 SIDSFVREW------TKHQIDVIV------RRTRFRLRKAEEQIHI----------YRGYLKALDALDEVIATIRrspdV 438
Cdd:COG4913 208 DLDDFVREYmleepdTFEAADALVehfddlERAHEALEDAREQIELlepirelaerYAAARERLAELEYLRAALR----L 283
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 514222660 439 DEARTALiALLDIDEIQANAILALQLRRLAALERQkITEEHDRLAALILEYEEILGS--EQRQREIVSEELEA 509
Cdd:COG4913 284 WFAQRRL-ELLEAELEELRAELARLEAELERLEAR-LDALREELDELEAQIRGNGGDrlEQLEREIERLEREL 354
|
|
| |
