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Conserved domains on  [gi|508536839|gb|EOX05215|]
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DsdX permease [Escherichia coli KTE225]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ArsB_NhaD_permease super family cl21473
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ...
1-72 9.99e-39

Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.


The actual alignment was detected with superfamily member PRK09921:

Pssm-ID: 473875  Cd Length: 445  Bit Score: 132.19  E-value: 9.99e-39
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 508536839   1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:PRK09921 374 MLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 445
 
Name Accession Description Interval E-value
PRK09921 PRK09921
permease DsdX; Provisional
1-72 9.99e-39

permease DsdX; Provisional


Pssm-ID: 182147  Cd Length: 445  Bit Score: 132.19  E-value: 9.99e-39
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 508536839   1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:PRK09921 374 MLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 445
gntP TIGR00791
gluconate transporter; This family includes known gluconate transporters of E. coli and ...
1-72 3.07e-22

gluconate transporter; This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 129873  Cd Length: 440  Bit Score: 87.80  E-value: 3.07e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 508536839    1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:TIGR00791 369 LLGQYSGVNPALLVLATGAGSVIASHVNDAGFWLFKEYFGLTVKETLKTWTLLETIISVVGLIGVLLLSLVL 440
GntP_permease pfam02447
GntP family permease; This is a family of integral membrane permeases that are involved in ...
1-71 5.12e-21

GntP family permease; This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter and GntT, a high affinity transporter.


Pssm-ID: 308194 [Multi-domain]  Cd Length: 440  Bit Score: 84.25  E-value: 5.12e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 508536839    1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFI 71
Cdd:pfam02447 370 IIAQLPGVNPALLVLATGAGSLILSHVNDAGFWLFKEYFGLTVKETLKTWTVLETILSVVGLIGTLLLSLV 440
GntT COG2610
H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and ...
7-72 3.08e-12

H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and metabolism];


Pssm-ID: 442022 [Multi-domain]  Cd Length: 440  Bit Score: 59.36  E-value: 3.08e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 508536839   7 DISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:COG2610  374 GVSPELLVLAIGAGSGGLSHVNDSGFWLVKEYFGLTVKETLKTWTVMTTIIGVVGLVLVLILSLLF 439
 
Name Accession Description Interval E-value
PRK09921 PRK09921
permease DsdX; Provisional
1-72 9.99e-39

permease DsdX; Provisional


Pssm-ID: 182147  Cd Length: 445  Bit Score: 132.19  E-value: 9.99e-39
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 508536839   1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:PRK09921 374 MLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 445
gntP TIGR00791
gluconate transporter; This family includes known gluconate transporters of E. coli and ...
1-72 3.07e-22

gluconate transporter; This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 129873  Cd Length: 440  Bit Score: 87.80  E-value: 3.07e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 508536839    1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:TIGR00791 369 LLGQYSGVNPALLVLATGAGSVIASHVNDAGFWLFKEYFGLTVKETLKTWTLLETIISVVGLIGVLLLSLVL 440
GntP_permease pfam02447
GntP family permease; This is a family of integral membrane permeases that are involved in ...
1-71 5.12e-21

GntP family permease; This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter and GntT, a high affinity transporter.


Pssm-ID: 308194 [Multi-domain]  Cd Length: 440  Bit Score: 84.25  E-value: 5.12e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 508536839    1 MLALYPDISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFI 71
Cdd:pfam02447 370 IIAQLPGVNPALLVLATGAGSLILSHVNDAGFWLFKEYFGLTVKETLKTWTVLETILSVVGLIGTLLLSLV 440
GntT COG2610
H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and ...
7-72 3.08e-12

H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and metabolism];


Pssm-ID: 442022 [Multi-domain]  Cd Length: 440  Bit Score: 59.36  E-value: 3.08e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 508536839   7 DISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:COG2610  374 GVSPELLVLAIGAGSGGLSHVNDSGFWLVKEYFGLTVKETLKTWTVMTTIIGVVGLVLVLILSLLF 439
PRK14984 PRK14984
gluconate transporter;
8-72 4.81e-08

gluconate transporter;


Pssm-ID: 237880  Cd Length: 438  Bit Score: 47.48  E-value: 4.81e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 508536839   8 ISPEIFTIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:PRK14984 374 VSPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI 438
PRK09821 PRK09821
putative transporter; Provisional
14-72 9.48e-04

putative transporter; Provisional


Pssm-ID: 182094  Cd Length: 454  Bit Score: 35.40  E-value: 9.48e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 508536839  14 TIDIGSSAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII 72
Cdd:PRK09821 396 TLAACFGGLGLSHVNDSGFWIVTKYLGLSVADGLKTWTVLTTILGLTGFLITWCVWAVI 454
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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