NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|431712172|gb|ELJ76474|]
View 

protein hokC [Escherichia coli KTE82]

Protein Classification

type I toxin-antitoxin system Hok family toxin( domain architecture ID 10486807)

type I toxin-antitoxin system Hok family toxin similar to Hok, a small, toxic protein encoded on the parB (hok/sok) locus of plasmid R1, that mediates plasmid stabilization by killing plasmid-free cells

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HOK_GEF pfam01848
Hok/gef family;
26-66 3.30e-13

Hok/gef family;


:

Pssm-ID: 426473  Cd Length: 41  Bit Score: 57.00  E-value: 3.30e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 431712172  26 MIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAY 66
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
 
Name Accession Description Interval E-value
HOK_GEF pfam01848
Hok/gef family;
26-66 3.30e-13

Hok/gef family;


Pssm-ID: 426473  Cd Length: 41  Bit Score: 57.00  E-value: 3.30e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 431712172  26 MIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAY 66
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
PRK09738 PRK09738
small toxic polypeptide; Provisional
 23-68 6.71e-08

small toxic polypeptide; Provisional


Pssm-ID: 182055  Cd Length: 52  Bit Score: 44.01  E-value: 6.71e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 431712172 23 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 68
Cdd:PRK09738  5 RSPLVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYES 50
 
Name Accession Description Interval E-value
HOK_GEF pfam01848
Hok/gef family;
26-66 3.30e-13

Hok/gef family;


Pssm-ID: 426473  Cd Length: 41  Bit Score: 57.00  E-value: 3.30e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 431712172  26 MIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAY 66
Cdd:pfam01848  1 ALVALIVICITVLLFTLVTRKSLCELRIRQGQTEVAAFLAC 41
PRK09738 PRK09738
small toxic polypeptide; Provisional
 23-68 6.71e-08

small toxic polypeptide; Provisional


Pssm-ID: 182055  Cd Length: 52  Bit Score: 44.01  E-value: 6.71e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 431712172 23 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 68
Cdd:PRK09738  5 RSPLVWCVLIVCLTLLIFTYLTRKSLCELRYRDGDREVAAFMAYES 50
PRK09759 PRK09759
type I toxin-antitoxin system toxin HokA;
23-65 3.33e-06

type I toxin-antitoxin system toxin HokA;


Pssm-ID: 182063  Cd Length: 50  Bit Score: 39.53  E-value: 3.33e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 431712172 23 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTA 65
Cdd:PRK09759  3 QKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLA 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH