|
Name |
Accession |
Description |
Interval |
E-value |
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
62-449 |
2.29e-172 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 488.53 E-value: 2.29e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 62 VILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFHT 141
Cdd:cd00751 1 VIVSAVRTPIGR-FGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 142 VNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNYQSRGIPQDVGPTLHNTKV------KAASDCLMPMGITSENV 215
Cdd:cd00751 80 VNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDgmlddgLTDPFTGLSMGITAENV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 216 ARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydnetGKTSQVRVAADDTIRPNVTLEKLAKLKPAFLED 295
Cdd:cd00751 160 AEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVP------GRKGPVVVDRDEGPRPDTTLEKLAKLKPAFKKD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 296 GGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEA 375
Cdd:cd00751 234 GTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEA 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 342870877 376 FASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVasAIIVE 449
Cdd:cd00751 314 FAAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGGQGA--AMVIE 385
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
59-449 |
7.95e-161 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 459.15 E-value: 7.95e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL-AELGFAkTGRMALLHAGFPTST 137
Cdd:COG0183 2 REVVIVDAVRTPFGR-FGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLqAGQGQN-PARQAALLAGLPESV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 138 TFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMS-------KNYQSRGIPQDVGPTLHNTKVKAASDClMPMGI 210
Cdd:COG0183 80 PAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSrapmllpKARWGYRMNAKLVDPMINPGLTDPYTG-LSMGE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 211 TSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydnetGKTSQVRVAADDTIRPNVTLEKLAKLKP 290
Cdd:COG0183 159 TAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVP------DRKGEVVVDRDEGPRPDTTLEKLAKLKP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 291 AFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVI 370
Cdd:COG0183 233 AFKKDGTVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLI 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 342870877 371 ELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVasAIIVE 449
Cdd:COG0183 313 EINEAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCIGGGQGI--ALIIE 389
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
54-446 |
1.76e-157 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 453.07 E-value: 1.76e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 54 TTKSPNDVVILSAVRSPITRAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAE-LGFAKTGRMALLHAG 132
Cdd:PLN02287 41 TTAFGDDVVIVAAYRTPICKAKRGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPgSQRANECRMAAFYAG 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 133 FPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNyqsrGIPQDVGPtlhNTKVKA---ASDCLMPMG 209
Cdd:PLN02287 121 FPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTN----PMAWEGGV---NPRVESfsqAQDCLLPMG 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 210 ITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVYDNETGKTSQVRVAADDTIRPNVTLEKLAKLK 289
Cdd:PLN02287 194 ITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKIVDPKTGEEKPIVISVDDGIRPNTTLADLAKLK 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 290 PAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDV 369
Cdd:PLN02287 274 PVFKKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLELDDIDL 353
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 342870877 370 IELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEV--GVISMCASTGIGVASAI 446
Cdd:PLN02287 354 FEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGKDCrfGVVSMCIGTGMGAAAVF 432
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
63-449 |
2.43e-148 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 427.41 E-value: 2.43e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 63 ILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFHTV 142
Cdd:TIGR01930 1 IVAAARTPIGK-FGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 143 NRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKN--YQSRGIPQDVGP---TLHNTKVKAASD--CLMPMGITSENV 215
Cdd:TIGR01930 80 NRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVpyGVPRSLRWGVKPgnaELEDARLKDLTDanTGLPMGVTAENL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 216 ARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIeyTVYDNETGKTsqvrVAADDTIRPNVTLEKLAKLKPAFLED 295
Cdd:TIGR01930 160 AKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPV--TVKGRKGPVT----VSSDEGIRPNTTLEKLAKLKPAFDPD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 296 GGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEA 375
Cdd:TIGR01930 234 GTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEA 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 342870877 376 FASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGvaSAIIVE 449
Cdd:TIGR01930 314 FAAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGGQG--AAVILE 385
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
58-449 |
3.32e-128 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 376.41 E-value: 3.32e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 58 PNDVVILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL-AELGfAKTGRMALLHAGFPTS 136
Cdd:PRK05790 1 MKDVVIVSAARTPIGK-FGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLqAGAG-QNPARQAALKAGLPVE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 137 TTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKN----YQSRGipqdvGPTLHNTKVK--AASDCL----- 205
Cdd:PRK05790 79 VPALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAphvlPGSRW-----GQKMGDVELVdtMIHDGLtdafn 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 206 -MPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydneTGKTSQVRVAADDTIRPNVTLEK 284
Cdd:PRK05790 154 gYHMGITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIK-----QRKGDPVVVDTDEHPRPDTTAES 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 285 LAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQ 364
Cdd:PRK05790 229 LAKLRPAFDKDGTVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 365 KDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVas 444
Cdd:PRK05790 309 ADLDLIEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCIGGGQGV-- 386
|
....*
gi 342870877 445 AIIVE 449
Cdd:PRK05790 387 ALIVE 391
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
55-443 |
2.13e-115 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 343.91 E-value: 2.13e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 55 TKSPNDVVILSAVRSPITRAFKGGFKDAWPEDILAPVMAEA-ARRAKIQSGDVQDVLIGNVLAElgfAKTG----RMALL 129
Cdd:PRK09052 2 SKQLQDAYIVAATRTPVGKAPRGMFKNTRPDDLLAHVLRSAvAQVPGLDPKLIEDAIVGCAMPE---AEQGlnvaRIGAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 130 HAGFPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSknyqsrgipqdVGPTLHNtKVKAASDCLMP-- 207
Cdd:PRK09052 79 LAGLPNSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMS-----------MVPMMGN-KPSMSPAIFARde 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 208 -------MGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVY--DNETGK--TSQVRVAADDTI 276
Cdd:PRK09052 147 nvgiaygMGLTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEITERfpDLATGEvdVKTRTVDLDEGP 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 277 RPNVTLEKLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRL 356
Cdd:PRK09052 227 RADTSLEGLAKLKPVFANKGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 357 YKYVGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCA 436
Cdd:PRK09052 307 LKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMCV 386
|
....*..
gi 342870877 437 STGIGVA 443
Cdd:PRK09052 387 GTGMGAA 393
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
57-446 |
1.78e-111 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 333.85 E-value: 1.78e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 57 SPNDVVILSAVRSPITrAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL-AELGFAKTGRMALLHAGFPT 135
Cdd:PRK09051 1 MMREVVVVSGVRTAIG-TFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIpTEPRDMYLSRVAAINAGVPQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 136 STTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKN-YQSRGipQDVGPTLHNTK-----VKAASDCL--MP 207
Cdd:PRK09051 80 ETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRApYLLPA--ARWGARMGDAKlvdmmVGALHDPFgtIH 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 208 MGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVydnetgKTSQVRVAADDTIRPNVTLEKLAK 287
Cdd:PRK09051 158 MGVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEIKT------RKGEVVFDTDEHVRADTTLEDLAK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 288 LKPAFLEDGGS-TAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKD 366
Cdd:PRK09051 232 LKPVFKKENGTvTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVAD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 367 VDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVASAI 446
Cdd:PRK09051 312 LDVIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCIGGGQGIAAIF 391
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
62-443 |
1.70e-109 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 328.63 E-value: 1.70e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 62 VILSAVRSPITRAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL--AELGFAKTGRMALLhAGFPTSTTF 139
Cdd:PRK07661 5 VIVAGARTPVGKAKKGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMpeAEQGLNMARNIGAL-AGLPYTVPA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 140 HTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsrgIP---QDVGPTLHntKVKAASDCLMPMGITSENVA 216
Cdd:PRK07661 84 ITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSL------VPmmgHVVRPNPR--LVEAAPEYYMGMGHTAEQVA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 217 RRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYT---VYDNETGKTSQVRVAADDTIRPNVTLEKLAKLKPAFL 293
Cdd:PRK07661 156 VKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVTlrtVGENNKLQEETITFSQDEGVRADTTLEILGKLRPAFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 294 EDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELN 373
Cdd:PRK07661 236 VKGSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELN 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 374 EAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVA 443
Cdd:PRK07661 316 EAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAA 385
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
59-443 |
2.75e-108 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 325.57 E-value: 2.75e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITRAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAElgfAKTG----RMALLHAGFP 134
Cdd:PRK07108 2 TEAVIVSTARTPLAKSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPE---GATGaniaRQIALRAGLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 135 TSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMS--KNYQSRGIPQDVGPTLHNTKVkaasdcLMPMGITS 212
Cdd:PRK07108 79 VTVPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESIScvQNEMNRHMLREGWLVEHKPEI------YWSMLQTA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 213 ENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYT--VYDNETGK--TSQVRVAADDTIRPNVTLEKLAKL 288
Cdd:PRK07108 153 ENVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTagVADKATGRlfTKEVTVSADEGIRPDTTLEGVSKI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 289 KPAfLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVD 368
Cdd:PRK07108 233 RSA-LPGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDID 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 342870877 369 VIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVA 443
Cdd:PRK07108 312 LWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAA 386
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
58-446 |
1.33e-106 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 321.14 E-value: 1.33e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 58 PNDVVILSAVRSPITRAFKGGFKDAWPEDILAPVM-AEAARRAKIQSGDVQDVLIGNV--LAELGFaKTGRMALLHAGFP 134
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMrSLLARNPALDPAEIDDIIWGCVqqTLEQGF-NIARNAALLAGIP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 135 TSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNYQSRGIpqDVGPTLHNTKVKAAsdclMPMGITSEN 214
Cdd:PRK08947 80 HSVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMNHGV--DFHPGLSKNVAKAA----GMMGLTAEM 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 215 VARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYtvyDNETGktSQVRVAADDTIRPNVTLEKLAKLKPAFLE 294
Cdd:PRK08947 154 LGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEG---HDADG--VLKLFDYDEVIRPETTVEALAALRPAFDP 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 295 DGGS-TAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELN 373
Cdd:PRK08947 229 VNGTvTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELN 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 342870877 374 EAFASQTLACINKLGL-DV--DKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVASAI 446
Cdd:PRK08947 309 EAFAAQSLPCLKDLGLlDKmdEKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLGQGIATVF 384
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
60-443 |
8.03e-99 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 301.91 E-value: 8.03e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTF 139
Cdd:PRK06205 3 DAVICEPVRTPVGR-FGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVPG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 140 HTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSK-NYQSRGIPQDV---GPTLHNTKVKAAsdcLMPMGI----- 210
Cdd:PRK06205 82 MQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNvEFYTTDMRWGVrggGVQLHDRLARGR---ETAGGRrfpvp 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 211 -----TSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydneTGKTSQVRVAADDTIRPNVTLEKL 285
Cdd:PRK06205 159 ggmieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVP-----QRKGDPTVVDRDEHPRADTTLESL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 286 AKLKPAFL---EDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGI 362
Cdd:PRK06205 234 AKLRPIMGkqdPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 363 GQKDVDVIELNEAFASQTLACINKLGL---DVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTG 439
Cdd:PRK06205 314 TLDDIDLIELNEAFAAQVLAVLKEWGFgadDEERLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMCIGGG 393
|
....
gi 342870877 440 IGVA 443
Cdd:PRK06205 394 QGLA 397
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
59-446 |
4.07e-97 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 297.25 E-value: 4.07e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITRaFKGGFKDAWPEDILA-PVMAEAARRAKIQSGDVQDVLIG----------NVlaelgfaktGRMA 127
Cdd:PRK09050 2 TEAFICDAIRTPIGR-YGGALSSVRADDLGAvPLKALMARNPGVDWEAVDDVIYGcanqagednrNV---------ARMS 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 128 LLHAGFPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKN----------YQSRGIPQD--VGPTLHN 195
Cdd:PRK09050 72 ALLAGLPVSVPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRApfvmgkadsaFSRQAEIFDttIGWRFVN 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 196 TKVKAA--SDclmPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydneTGKTSQVRVAAD 273
Cdd:PRK09050 152 PLMKAQygVD---SMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIP-----QKKGDPVVVDRD 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 274 DTIRPNVTLEKLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAI 353
Cdd:PRK09050 224 EHPRPETTLEALAKLKPVFRPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPAT 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 354 PRLYKYVGIGQKDVDVIELNEAFASQTLACINKLGL--DVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGV 431
Cdd:PRK09050 304 RKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYAL 383
|
410
....*....|....*
gi 342870877 432 ISMCASTGIGVASAI 446
Cdd:PRK09050 384 CTMCIGVGQGIALAI 398
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
60-449 |
1.98e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 293.06 E-value: 1.98e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSPITRAFKGGFKDAWPEDiLAPVMAEAARrAKIQS---GDVQDVLIGNVL--AELGFaKTGRMALLHAGFP 134
Cdd:PRK07851 3 EAVIVSTARSPIGRAFKGSLKDMRPDD-LAAQMVRAAL-DKVPAldpTDIDDLMLGCGLpgGEQGF-NMARVVAVLLGYD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 135 TsTTFHTVNRQCSSSLQAlTHMA-HAIQAGQIDVALAGGVESMSKNYQSRGipqDVGPTLHN---------TKVKAAS-- 202
Cdd:PRK07851 80 F-LPGTTVNRYCSSSLQT-TRMAfHAIKAGEGDVFISAGVETVSRFAKGNS---DSLPDTKNplfaeaqarTAARAEGga 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 203 -------------DCLMPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIeyTVYDNETgktsqvr 269
Cdd:PRK07851 155 eawhdpredgllpDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPV--TLPDGTV------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 270 VAADDTIRPNVTLEKLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGP 349
Cdd:PRK07851 226 VSTDDGPRAGTTYEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGP 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 350 IYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEV 429
Cdd:PRK07851 306 VEASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTF 385
|
410 420
....*....|....*....|
gi 342870877 430 GVISMCASTGIGVasAIIVE 449
Cdd:PRK07851 386 GLETMCVGGGQGM--AMVLE 403
|
|
| pcaF |
TIGR02430 |
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, ... |
59-446 |
2.83e-89 |
|
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, an enzyme that acts at the end of pathways for the degradation of protocatechuate (from benzoate and related compounds) and of phenylacetic acid.
Pssm-ID: 131483 Cd Length: 400 Bit Score: 277.05 E-value: 2.83e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITRaFKGGFKDAWPEDILA-PVMAEAARRAKIQSGDVQDVLIG--NVLAELGfAKTGRMALLHAGFPT 135
Cdd:TIGR02430 1 REAYICDAIRTPIGR-YGGSLSSVRADDLAAvPIKALLARNPQLDWAAIDDVIYGcaNQAGEDN-RNVARMAALLAGLPV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 136 STTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNYQSRGIPQDV---GPTLHNTKVK--------AASDC 204
Cdd:TIGR02430 79 SVPGTTVNRLCGSGLDAIGMAARAIKAGEADLLIAGGVESMSRAPFVMGKADSAfsrSAKIEDTTIGwrfinplmKALYG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 205 LMPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYtvydnETGKTSQVRVAADDTIRPNVTLEK 284
Cdd:TIGR02430 159 VDSMPETAENVAEEFGISREDQDAFALRSQQRTAAAQASGFFAEEIVPVVI-----PQKKGEPTVVDQDEHPRPETTLEG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 285 LAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQ 364
Cdd:TIGR02430 234 LAKLKPVVRPDGTVTAGNASGVNDGAAALLLASEEAVQRHGLTPRARILAAATAGVEPRIMGIGPVPATQKLLARAGLSI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 365 KDVDVIELNEAFASQTLACINKLGL--DVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGV 442
Cdd:TIGR02430 314 DQFDVIELNEAFAAQALAVLRELGLadDDARVNPNGGAIALGHPLGASGARLVLTALRQLERSGGRYALCTMCIGVGQGI 393
|
....
gi 342870877 443 ASAI 446
Cdd:TIGR02430 394 ALAI 397
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
60-446 |
6.92e-89 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 276.27 E-value: 6.92e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNV-LAELGFAKTGRMALLHAGFPTSTT 138
Cdd:PRK08131 3 DAYIYDGLRSPFGR-HAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTnQAGEDSRNVARNALLLAGLPVTVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 139 FHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNYQSRGIPQD------------VGPTLHNTK-VKAASDCL 205
Cdd:PRK08131 82 GQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPFVMGKAESafsrdakvfdttIGARFPNPKiVAQYGNDS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 206 MPMgiTSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydnETGKTSQVRVAADDTIRPNVTLEKL 285
Cdd:PRK08131 162 MPE--TGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVP----QGRKLPPKLVAEDEHPRPSSTVEAL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 286 AKLKPAFlEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQK 365
Cdd:PRK08131 236 TKLKPLF-EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 366 DVDVIELNEAFASQTLACINKLGLDVD--KVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVA 443
Cdd:PRK08131 315 DMDIIEINEAFASQVLGCLKGLGVDFDdpRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCIGVGQGLA 394
|
...
gi 342870877 444 SAI 446
Cdd:PRK08131 395 MVI 397
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
60-449 |
2.31e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 274.68 E-value: 2.31e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSPITRAF-----KGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL-AELGFAKTGRMALLHAGF 133
Cdd:PRK06445 3 DVYLVDFARTAFSRFRpkdpqKDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALqVGENWLYGGRHPIFLARL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 134 PTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsrgIPQDVGPTLH-NTKVKAASDCL------- 205
Cdd:PRK06445 83 PYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTR------TPMGDNPHIEpNPKLLTDPKYIeydlttg 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 206 MPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVydneTGKTSQVRVaaDDTIRPNVTLEKL 285
Cdd:PRK06445 157 YVMGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEV----EGKKKVVDV--DQSVRPDTSLEKL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 286 AKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQK 365
Cdd:PRK06445 231 AKLPPAFKPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVK 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 366 DVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVasA 445
Cdd:PRK06445 311 DIDLWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCVGGGQGG--A 388
|
....
gi 342870877 446 IIVE 449
Cdd:PRK06445 389 VVLE 392
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
62-449 |
1.46e-87 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 272.36 E-value: 1.46e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 62 VILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFHT 141
Cdd:PRK08235 5 VIVSAARTPFGK-FGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQTET 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 142 VNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsrgIPQDV-----GPTLHNTKVK--AASDCL------MPM 208
Cdd:PRK08235 84 VNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSN------APYILpgarwGYRMGDNEVIdlMVADGLtcafsgVHM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 209 GITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydNETGKTsqVRVAADDTIRPNVTLEKLAKL 288
Cdd:PRK08235 158 GVYGGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIP---QRKGDP--IVVAKDEAPRKDTTIEKLAKL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 289 KPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVD 368
Cdd:PRK08235 233 KPVFDKTGTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDID 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 369 VIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGvaSAIIV 448
Cdd:PRK08235 313 LFEINEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSGGGQG--DAVLI 390
|
.
gi 342870877 449 E 449
Cdd:PRK08235 391 E 391
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
60-449 |
1.64e-84 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 264.65 E-value: 1.64e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSPITrAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL-AELGFAKtGRMALLHAGFPTSTT 138
Cdd:PLN02644 2 DVCIVGVARTPIG-GFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLsANLGQAP-ARQAALGAGLPPSTI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 139 FHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSK--NYQSRGIPqdvGPTL-HNTKVKAA-SDCL------MPM 208
Cdd:PLN02644 80 CTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNapKYLPEARK---GSRLgHDTVVDGMlKDGLwdvyndFGM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 209 GITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVydnETGKTSQVrVAADDTIRpNVTLEKLAKL 288
Cdd:PLN02644 157 GVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPG---GRGRPSVI-VDKDEGLG-KFDPAKLRKL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 289 KPAFLEDGGS-TAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDV 367
Cdd:PLN02644 232 RPSFKEDGGSvTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 368 DVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCasTGIGVASAII 447
Cdd:PLN02644 312 DYYEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGIC--NGGGGASAIV 389
|
..
gi 342870877 448 VE 449
Cdd:PLN02644 390 VE 391
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
62-446 |
7.59e-84 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 262.74 E-value: 7.59e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 62 VILSAVRSPITRAfKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVlIGNVLAELG--FAKTGRMALLHAGFPTSTTF 139
Cdd:PRK07850 5 VIVEAVRTPIGKR-NGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQV-IGGCVTQAGeqSNNITRTAWLHAGLPYHVGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 140 HTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNYQSRGIPQDVGPtlhntkVKAAS-DCLMPMGITS-ENVAR 217
Cdd:PRK07850 83 TTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANAGPGRGL------PRPDSwDIDMPNQFEAaERIAK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 218 RHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVYDNETGKTSQVRVAADDTIRPNVTLEKLAKLKPAfLEDGG 297
Cdd:PRK07850 157 RRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEGQPTGETRLVTRDQGLRDTTMEGLAGLKPV-LEGGI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 298 STAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFA 377
Cdd:PRK07850 236 HTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLVEINEAFA 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 342870877 378 SQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVASAI 446
Cdd:PRK07850 316 SVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGGALSTGTII 384
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
63-449 |
6.55e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 255.02 E-value: 6.55e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 63 ILSAVRSPITRAfKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFA-KTGRMALLHAGFPTSTTFHT 141
Cdd:PRK07801 6 IVDAVRTPVGKR-KGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAgNIARTSWLAAGLPEEVPGVT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 142 VNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsrgIPqdvgptlhntkVKAASDCLMPMGITS--------- 212
Cdd:PRK07801 85 VDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQ------IP-----------ISSAMTAGEQLGFTSpfaeskgwl 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 213 --------------ENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEytvydnetgktsqvRVAADDTIRp 278
Cdd:PRK07801 148 hrygdqevsqfrgaELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVG--------------GVTVDEGPR- 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 279 NVTLEKLAKLKPafLEDGGS-TAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLY 357
Cdd:PRK07801 213 ETSLEKMAGLKP--LVEGGRlTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYAL 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 358 KYVGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCas 437
Cdd:PRK07801 291 EKTGLSIDDIDVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMC-- 368
|
410
....*....|..
gi 342870877 438 TGIGVASAIIVE 449
Cdd:PRK07801 369 EGGGTANVTIIE 380
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
59-446 |
6.42e-77 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 245.18 E-value: 6.42e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITrAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTT 138
Cdd:PRK05656 2 QDVVIVAATRTAIG-SFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 139 FHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMS---------KNYQSRGIPQDVGPTLHNTKVKAASDclMPMG 209
Cdd:PRK05656 81 AMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSlapyvlpgaRTGLRMGHAQLVDSMITDGLWDAFND--YHMG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 210 ITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydneTGKTSQVRVAADDTIRPNVTLEKLAKLK 289
Cdd:PRK05656 159 ITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIP-----QRKGEPLAFATDEQPRAGTTAESLAKLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 290 PAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDV 369
Cdd:PRK05656 234 PAFKKDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDL 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 342870877 370 IELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVASAI 446
Cdd:PRK05656 314 IEANEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALAI 390
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
87-446 |
1.35e-76 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 244.17 E-value: 1.35e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 87 ILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQID 166
Cdd:PRK06633 30 LAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVPGYTINKVCGSGLKSVALAANSIMTGDNE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 167 VALAGGVESMSKnyqsrgipqdvgpTLHNTKVKAAS---DCLMP----------------MGITSENVARRHGVDRKMQD 227
Cdd:PRK06633 110 IVIAGGQENMSL-------------GMHGSYIRAGAkfgDIKMVdlmqydgltdvfsgvfMGITAENISKQFNISRQEQD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 228 EYALLSHTRANEALAAGRFEAEIVPIEYTVydnetgKTSQVRVAADDTIRPNVTLEKLAKLKPAFLEDGGSTAGNSSQIS 307
Cdd:PRK06633 177 EFALSSHKKAAKAQLAGIFKDEILPIEVTI------KKTTSLFDHDETVRPDTSLEILSKLRPAFDKNGVVTAGNASSIN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 308 DGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACINKL 387
Cdd:PRK06633 251 DGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNEAFAAQSIYVNREM 330
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 342870877 388 GLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVASAI 446
Cdd:PRK06633 331 KWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCIGGGMGMAMCV 389
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
61-319 |
1.65e-76 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 239.51 E-value: 1.65e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 61 VVILSAVRSPITRaFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFH 140
Cdd:pfam00108 1 VVIVSAARTPFGS-FGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 141 TVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNyqsrgipqdvgPTLHNTKVKA--------ASDCLMP----- 207
Cdd:pfam00108 80 TINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHA-----------PYALPTDARSglkhgdekKHDLLIPdgltd 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 208 ------MGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIeytvydNETGKTSQVRVAADDTIRPNVT 281
Cdd:pfam00108 149 afngyhMGLTAENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPV------TVKGRKGKPTVDKDEGIRPPTT 222
|
250 260 270
....*....|....*....|....*....|....*...
gi 342870877 282 LEKLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRS 319
Cdd:pfam00108 223 AEPLAKLKPAFDKEGTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
60-446 |
4.18e-75 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 240.56 E-value: 4.18e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSPITRAFKGG-FKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNV--LAELGfAKTGRMALLHAGFPTS 136
Cdd:PRK08242 3 EAYIYDAVRTPRGKGKKDGsLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVtpVGDQG-ADIARTAVLAAGLPET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 137 TTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsRGIPQDVGPTLHNTKVKAASDcLMPMGITSENVA 216
Cdd:PRK08242 82 VPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSR----VPMGSDGGAWAMDPSTNFPTY-FVPQGISADLIA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 217 RRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEytvydNETGktsQVRVAADDTIRPNVTLEKLAKLKPAFL--- 293
Cdd:PRK08242 157 TKYGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVK-----DQNG---LTILDHDEHMRPGTTMESLAKLKPSFAmmg 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 294 EDGG------------------STAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPR 355
Cdd:PRK08242 229 EMGGfdavalqkypeverinhvHHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 356 LYKYVGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMC 435
Cdd:PRK08242 309 ALAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITLC 388
|
410
....*....|.
gi 342870877 436 ASTGIGVASAI 446
Cdd:PRK08242 389 VGGGMGIATII 399
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
59-443 |
5.23e-75 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 238.90 E-value: 5.23e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITRAfKGGFKDAWPEDILAPVMAEAARRAKiqsGDVQDVLIGNVLAELGfaKTGRMALLHAGFPTSTT 138
Cdd:PRK06690 1 NRAVIVEAKRTPIGKK-NGMLKDYEVQQLAAPLLTFLSKGME---REIDDVILGNVVGPGG--NVARLSALEAGLGLHIP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 139 FHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKN-YQSRG--IPQDVGPTlhntkvkaasdclmPMGITSENV 215
Cdd:PRK06690 75 GVTIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSpFQNRArfSPETIGDP--------------DMGVAAEYV 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 216 ARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTvydnetgktsqvrvaADDTIRPNVTLEKL-AKLKPAFLE 294
Cdd:PRK06690 141 AERYNITREMQDEYACLSYKRTLQALEKGYIHEEILSFNGL---------------LDESIKKEMNYERIiKRTKPAFLH 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 295 DGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNE 374
Cdd:PRK06690 206 NGTVTAGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINE 285
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 342870877 375 AFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVA 443
Cdd:PRK06690 286 AFASKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLA 354
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
58-449 |
3.47e-74 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 238.76 E-value: 3.47e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 58 PNDVVILSAVRSPITRAfKGGfkdawPEDILAPVMAEAARRAKI-----QSGDVQDVLIGNVLAELGFAKTGRMALLHAG 132
Cdd:PRK08170 2 ARPVYIVDGARTPFLKA-RGG-----PGPFSASDLAVAAGRALLnrqpfAPDDLDEVILGCAMPSPDEANIARVVALRLG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 133 FPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKN---------------YQSRGI-----------P 186
Cdd:PRK08170 76 CGEKVPAWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHApllfsekmvrwlagwYAAKSIgqklaalgklrP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 187 QDVGPTLhnTKVKAASD--CLMPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFeAEIVPI---EYTVYDne 261
Cdd:PRK08170 156 SYLAPVI--GLLRGLTDpvVGLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRL-KEVVPLfdrDGKFYD-- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 262 tgktsqvrvaADDTIRPNVTLEKLAKLKPAFLEDGGS-TAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGC 340
Cdd:PRK08170 231 ----------HDDGVRPDSSMEKLAKLKPFFDRPYGRvTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAAL 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 341 EPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACI----------NKLGLDV-------DKVNPNGGAIAI 403
Cdd:PRK08170 301 DPSQMGLGPVHAATPLLQRHGLTLEDLDLWEINEAFAAQVLACLaawadeeycrEQLGLDGalgeldrERLNVDGGAIAL 380
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 342870877 404 GHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGvaSAIIVE 449
Cdd:PRK08170 381 GHPVGASGARIVLHLLHALKRRGTKRGIAAICIGGGQG--GAMLLE 424
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
63-449 |
1.52e-73 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 236.16 E-value: 1.52e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 63 ILSAVRSPITRafKGGFKDAW-PEDILAPVMAEAARRAKIQSGDVQDVLIGNV--LAELGFAkTGRMALLHAGFPTSTTF 139
Cdd:PRK06504 6 IVAAARTAGGR--KGGRLAGWhPADLAAQVLDALVDRSGADPALIEDVIMGCVsqVGEQATN-VARNAVLASKLPESVPG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 140 HTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSK----------------NYQSRGIPQDVgPTLHNTKVKAAsd 203
Cdd:PRK06504 83 TSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRvpmgspstlpaknglgHYKSPGMEERY-PGIQFSQFTGA-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 204 clmpmgitsENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVYDNETgktsqVRVAADDTIRPNVTLE 283
Cdd:PRK06504 160 ---------EMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRADGSG-----EMHTVDEGIRFDATLE 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 284 KLAKLKPaFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIG 363
Cdd:PRK06504 226 GIAGVKL-IAEGGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 364 QKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCasTGIGVA 443
Cdd:PRK06504 305 IDDIDLYEVNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMC--EGGGMA 382
|
....*.
gi 342870877 444 SAIIVE 449
Cdd:PRK06504 383 NVTIVE 388
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
55-449 |
2.90e-71 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 231.41 E-value: 2.90e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 55 TKSPNDVVILSAVRSPITRAfKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFP 134
Cdd:PRK08963 1 TRQGDRIAIVSGLRTPFAKQ-ATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 135 TSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsrgIPQDVGPTLHNTKV---KAAS--------- 202
Cdd:PRK08963 80 VHTDAYSVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSV------LPIGVSKKLARALVdlnKARTlgqrlklfs 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 203 -----DcLMP-------------MGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVpieyTVYDNETGK 264
Cdd:PRK08963 154 rlrlrD-LLPvppavaeystglrMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVM----TAHVPPYKQ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 265 TsqvrVAADDTIRPNVTLEKLAKLKPAFLEDGGS-TAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEP- 342
Cdd:PRK08963 229 P----LEEDNNIRGDSTLEDYAKLRPAFDRKHGTvTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVw 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 343 DEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACI----------NKLG-------LDVDKVNPNGGAIAIGH 405
Cdd:PRK08963 305 QDMLLGPAYATPLALERAGLTLADLTLIDMHEAFAAQTLANLqmfaserfarEKLGrsqaigeVDMSKFNVLGGSIAYGH 384
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 342870877 406 PTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGvaSAIIVE 449
Cdd:PRK08963 385 PFAATGARMITQTLHELRRRGGGLGLTTACAAGGLG--AAMVLE 426
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
60-449 |
1.16e-68 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 224.27 E-value: 1.16e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 60 DVVILSAVRSP--ITRAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGnVLAELGF--AKTGRMALLHAGFPT 135
Cdd:PRK06025 3 EAYIIDAVRTPrgIGKVGKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWS-TSSQRGKqgGDLGRMAALDAGYDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 136 STTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMS--KNYQSRGIPQDVGPTLHNTKvKAASDCLMPM---GI 210
Cdd:PRK06025 82 KASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSytAAMAAEDMAAGKPPLGMGSG-NLRLRALHPQshqGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 211 TSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPieytVYDNEtgktSQVRVAADDTIRPNVTLEKLAKLKP 290
Cdd:PRK06025 161 CGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVP----VYRDD----GSVALDHEEFPRPQTTAEGLAALKP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 291 AF-------LEDGGST-------------------AGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDE 344
Cdd:PRK06025 233 AFtaiadypLDDKGTTyrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 345 MGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGR 424
Cdd:PRK06025 313 MLNAPVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELER 392
|
410 420
....*....|....*....|....*
gi 342870877 425 RGKEVGVISMCASTGIgvASAIIVE 449
Cdd:PRK06025 393 RGLKRGLVTMCAAGGM--APAIIIE 415
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
53-449 |
1.25e-68 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 223.62 E-value: 1.25e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 53 LTTKSPNDVVILSAVRSPITrAFKGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVL-AELGFAKtGRMALLHA 131
Cdd:PRK06954 1 MTAVDQDPIVIASAARTPMA-AFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLpAGQGQAP-ARQAALGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 132 GFPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKNY----QSR-GIPQDVGPTLHNTKVKAASDCL- 205
Cdd:PRK06954 79 GLPLSVGCTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPyllpKARgGMRMGHGQVLDHMFLDGLEDAYd 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 206 --MPMGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIeyTVydneTGKTSQVRVAADDTIRpNVTLE 283
Cdd:PRK06954 159 kgRLMGTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPV--TV----AGKKGDTVIDRDEQPF-KANPE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 284 KLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIG 363
Cdd:PRK06954 232 KIPTLKPAFSKTGTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 364 QKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCasTGIGVA 443
Cdd:PRK06954 312 AAEVDLFEINEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLC--IGGGEA 389
|
....*.
gi 342870877 444 SAIIVE 449
Cdd:PRK06954 390 TAMGIE 395
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
59-439 |
1.47e-67 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 220.65 E-value: 1.47e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 59 NDVVILSAVRSPITRaFKGGFkdawpEDILAPVMAEAARRA-----KIQSGDVQDVLIGNVL-AELGFAKTGRMALlHAG 132
Cdd:PRK06366 2 KDVYIVSAKRTAIGK-FGRSF-----SKIKAPQLGGAAIKAviddaKLDPALVQEVIMGNVIqAGVGQNPAGQAAY-HAG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 133 FPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyQSRGIPQDV--GPT--LH-NTKVKAA--SDCL 205
Cdd:PRK06366 75 LPFGVTKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSN--APFLLPSDLrwGPKhlLHkNYKIDDAmlVDGL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 206 MP------MGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIEYTVYDNETGKTsqvrvaaddtirpn 279
Cdd:PRK06366 153 IDafyfehMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFNDLDRDEGIRKT-------------- 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 280 vTLEKLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKY 359
Cdd:PRK06366 219 -TMEDLAKLPPAFDKNGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 360 VGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTG 439
Cdd:PRK06366 298 QNKSIDYYDLVEHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLCHGGG 377
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
53-447 |
1.18e-64 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 213.99 E-value: 1.18e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 53 LTTKSPNDVVILSAVRSPITRAFkGGFKDAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAG 132
Cdd:PRK09268 1 MTMPTVRRVAILGGNRIPFARSN-GAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 133 FPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMSKnyqsrgIPQDVGPTLHNT------------KVKA 200
Cdd:PRK09268 80 LSPYTPAYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSD------APIAVNEGLRKIllelnrakttgdRLKA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 201 ASDC----LMP-------------MGITSENVARRHGVDRKMQDEYALLSHTRANEALAAGRFEAEIVPIeytvydnetg 263
Cdd:PRK09268 154 LGKLrpkhLAPeiprngeprtglsMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPF---------- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 264 ktsqVRVAADDTIRPNVTLEKLAKLKPAF--LEDGGSTAGNSSQISDGASAAILARRSWATERGLKPVARFLGTQVAGCE 341
Cdd:PRK09268 224 ----LGLTRDNNLRPDSSLEKLAKLKPVFgkGGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAAVD 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 342 ----PDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLA----------CINKLGLDV-------DKVNPNGGA 400
Cdd:PRK09268 300 fvhgKEGLLMAPAYAVPRLLARNGLTLQDFDFYEIHEAFASQVLAtlkawedeeyCRERLGLDAplgsidrSKLNVNGSS 379
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 342870877 401 IAIGHPTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVAsAII 447
Cdd:PRK09268 380 LAAGHPFAATGGRIVATLAKLLAEKGSGRGLISICAAGGQGVT-AIL 425
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
89-446 |
2.36e-51 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 178.07 E-value: 2.36e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 89 APVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFHTVNRQCSSSLQALTHMAHAIQAGQIDVA 168
Cdd:cd00826 28 AKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIGMNNLCGSGLRALALAMQLIAGGDANCI 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 169 LAGGVESMSknYQSRGIPQDVGPTLHNTKVkAASDClmpmgitsenvarrhgvdrkmQDEYALLSHTRANEALAAGRFEA 248
Cdd:cd00826 108 LAGGFEKME--TSAENNAKEKHIDVLINKY-GMRAC---------------------PDAFALAGQAGAEAAEKDGRFKD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 249 EIVPIEYtvydneTGKTSQVRVAADDTIR--PNVTLEKLAKLKPAFLEDGGSTAGNSSQISDGASAAILARRSWATE--- 323
Cdd:cd00826 164 EFAKFGV------KGRKGDIHSDADEYIQfgDEASLDEIAKLRPAFDKEDFLTAGNACGLNDGAAAAILMSEAEAQKhgl 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 324 ----RGLKPVARFLGTQVAGCEPDE----MGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACINKLGLD----- 390
Cdd:cd00826 238 qskaREIQALEMITDMASTFEDKKVikmvGGDGPIEAARKALEKAGLGIGDLDLIEAHDAFAANACATNEALGLCpegqg 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 342870877 391 ---VDK----------VNPNGGAIAIGHPTGATGTRQLATLIAELGRR-----GKEVGVISMCASTGIGVASAI 446
Cdd:cd00826 318 galVDRgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEagkrqGAGAGLALLCIGGGGGAAMCI 391
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
326-446 |
1.54e-50 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 167.05 E-value: 1.54e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 326 LKPVARFLGTQVAGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACINKLGLDVDKVNPNGGAIAIGH 405
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 342870877 406 PTGATGTRQLATLIAELGRRGKEVGVISMCASTGIGVASAI 446
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMII 121
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
81-446 |
4.64e-20 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 91.17 E-value: 4.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 81 DAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTGRMALLHAGFPTSTTFHtVNRQCSSSLQALTHMAHAI 160
Cdd:cd00829 13 DRSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLLGKPATR-VEAAGASGSAAVRAAAAAI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 161 QAGQIDVALAGGVESMSknyqsrgipqdvgptlHNTKVKAASDCLMPMgitsenvarrhgvDRKMQDEYALLSHTrANEA 240
Cdd:cd00829 92 ASGLADVVLVVGAEKMS----------------DVPTGDEAGGRASDL-------------EWEGPEPPGGLTPP-ALYA 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 241 LAAGRfeaeivpieytvYDNETGKTSQV--RVAADD----------TIRPNVTLEKLAKLKP--AFLedggsTAGNSSQI 306
Cdd:cd00829 142 LAARR------------YMHRYGTTREDlaKVAVKNhrnaarnpyaQFRKPITVEDVLNSRMiaDPL-----RLLDCCPV 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 307 SDGASAAILARRSWATERGLKPVaRFLGTQVA--GCEPDEMG-----MGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQ 379
Cdd:cd00829 205 SDGAAAVVLASEERARELTDRPV-WILGVGAAsdTPSLSERDdflslDAARLAARRAYKMAGITPDDIDVAELYDCFTIA 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 380 TLACINKLGL---------------DVD---KVNPNGGAIAIGHPTGATGTRQLATLIAELGRRGKEVGVismcASTGIG 441
Cdd:cd00829 284 ELLALEDLGFcekgeggklvregdtAIGgdlPVNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARQV----PGARVG 359
|
....*
gi 342870877 442 VASAI 446
Cdd:cd00829 360 LAHNI 364
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
86-415 |
5.49e-16 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 79.35 E-value: 5.49e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 86 DILAPVMAEAARRAKIQSGDVQDVLIGNVLAELgFAKTGRM----ALLH---AGFPTSTtfHTVnrQCSS-SLQALTHMA 157
Cdd:PRK06289 28 DLTREVVDGTLAAAGVDADDIEVVHVGNFFGEL-FAGQGHLgampATVHpalWGVPASR--HEA--ACASgSVATLAAMA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 158 HaIQAGQIDVALAGGVESMsKNYQSRGIPQDVGPTLHNTKVKAASDCLMP--MGITSENVARRHGVDRKMQDEYALLSHT 235
Cdd:PRK06289 103 D-LRAGRYDVALVVGVELM-KTVPGDVAAEHLGAAAWTGHEGQDARFPWPsmFARVADEYDRRYGLDEEHLRAIAEINFA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 236 RA-NEALAAGRfeaeivpiEYTVYDNETGktsqvrvaADDTIRPNVtleklaklkpafleDGGSTAGNSSQISDGASAAI 314
Cdd:PRK06289 181 NArRNPNAQTR--------GWAFPDEATN--------DDDATNPVV--------------EGRLRRQDCSQVTDGGAGVV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 315 LARRSWATE-RGLKPVARFLG----TQVAGCEPD-EMGMGPIYAIPRL-------YKYVGIGQKDVDVIELNEAFASQTL 381
Cdd:PRK06289 231 LASDAYLRDyADARPIPRIKGwghrTAPLGLEQKlDRSAGDPYVLPHVrqavldaYRRAGVGLDDLDGFEVHDCFTPSEY 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 342870877 382 ACINKLGL-------------DVD-----KVNPNGGAIAIGHPTGATGTRQL 415
Cdd:PRK06289 311 LAIDHIGLtgpgeswkaiengEIAiggrlPINPSGGLIGGGHPVGASGVRML 362
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
300-427 |
1.05e-14 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 73.63 E-value: 1.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 300 AGNSSQISDGASAAILARRSWATERGLKPVARFLGTQV----AGCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEA 375
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAAtfdgASMVPAVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 342870877 376 FASQTLACINKLGLDVDKV---NPNGGAIAIGHPTGATGTRQLATLIAELGRRGK 427
Cdd:cd00327 174 GTPIGDAVELALGLDPDGVrspAVSATLIMTGHPLGAAGLAILDELLLMLEHEFI 228
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
90-427 |
3.92e-14 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 73.78 E-value: 3.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 90 PVMA-EAARRAKIQSG----DVQDVLIGNVLAElgfAKTGRMALLHAGFpTSTTFHTVNRQCSSSLQALTHMAHAIQAGQ 164
Cdd:PRK08256 23 PDMAaEAGRAALADAGidydAVQQAYVGYVYGD---STSGQRALYEVGM-TGIPIVNVNNNCSTGSTALFLARQAVRSGA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 165 IDVALAGGVESMSKNYQSRGIPQDVGPTLHNTKVKAA--SDCLMPM----------------GITSENVA------RRHG 220
Cdd:PRK08256 99 ADCALALGFEQMQPGALGSVWDDRPSPLERFDKALAElqGFDPAPPalrmfggagrehmekyGTTAETFAkigvkaRRHA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 221 VdrkmQDEYALLSHtranealaagrfeaeivpiEYTVYDnetgktsqvrVAADDTIRPNVTleKLAKLKPafledggsta 300
Cdd:PRK08256 179 A----NNPYAQFRD-------------------EYTLED----------VLASPMIWGPLT--RLQCCPP---------- 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 301 gnssqiSDGASAAILARRSWATERGLKP----VARFLGTQVAGC-EPDEM------GMGPIyAIPRLYKYVGIGQKDVDV 369
Cdd:PRK08256 214 ------TCGAAAAIVCSEEFARKHGLDRaveiVAQAMTTDTPSTfDGRSMidlvgyDMTRA-AAQQVYEQAGIGPEDIDV 286
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 342870877 370 IELNEAFASQTLACINKLGL-----------DVDK-------VNPNGGAIAIGHPTGATGTRQLATLIAELgrRGK 427
Cdd:PRK08256 287 VELHDCFSANELLTYEALGLcpegeaekfidDGDNtyggrwvVNPSGGLLSKGHPLGATGLAQCAELTWQL--RGT 360
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
86-439 |
3.10e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 61.45 E-value: 3.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 86 DILAPVMAEAARRAKIQSGDVQDVLIGNVLAEL--GFAKTGRMALLHAGF-PTSTTfhTVNRQCSSSLQALTHMAHAIQA 162
Cdd:PRK06064 24 DLAVEAGLEALEDAGIDGKDIDAMYVGNMSAGLfvSQEHIAALIADYAGLaPIPAT--RVEAACASGGAALRQAYLAVAS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 163 GQIDVALAGGVESMSknyqsrgipqDVGPTLHNTKVKAASDCLMP--MGITSEN----VARRHgvdrkMqDEYALlshTR 236
Cdd:PRK06064 102 GEADVVLAAGVEKMT----------DVPTPDATEAIARAGDYEWEefFGATFPGlyalIARRY-----M-HKYGT---TE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 237 anEALAagrfeaeivpiEYTVYDNETGktSQVRVAaddTIRPNVTLEKLAKLK----PAFLEDggstagnSSQISDGASA 312
Cdd:PRK06064 163 --EDLA-----------LVAVKNHYNG--SKNPYA---QFQKEITVEQVLNSPpvadPLKLLD-------CSPITDGAAA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 313 AILARRSWATERGLKPV-----ARFLGTQVAGCEPDEMGMGP-IYAIPRLYKYVGIGQKDVDVIELNEAFASQTLACINK 386
Cdd:PRK06064 218 VILASEEKAKEYTDTPVwikasGQASDTIALHDRKDFTTLDAaVVAAEKAYKMAGIEPKDIDVAEVHDCFTIAEILAYED 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 387 LGLdVDK-------------------VNPNGGAIAIGHPTGATGTRQLATLI------AELGRR---GKEVGVISMCAST 438
Cdd:PRK06064 298 LGF-AKKgeggklaregqtyiggdipVNPSGGLKAKGHPVGATGVSQAVEIVwqlrgeAEKGRQqviGAGYGLTHNVGGT 376
|
.
gi 342870877 439 G 439
Cdd:PRK06064 377 G 377
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
81-427 |
4.52e-09 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 58.12 E-value: 4.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 81 DAWPEDILAPVMAEAARRAKIQSGDVQDVLIGNVLAELGFAKTG---RMALLHAGFPTSTtfhtVNRQCSSSLQALTHMA 157
Cdd:PRK06157 24 DAGAEDLMVEAFLEALADAGIEPKDIDAAWFGTHYDEIGSGKSGtplSRALRLPNIPVTR----VENFCATGSEAFRGAV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 158 HAIQAGQIDVALAGGVESMsKNYQSRGIPQDVGPTLhntkvkaaSDCLMPMGITSENVAR-------RHGVDrkMQDEYA 230
Cdd:PRK06157 100 YAVASGAYDIALALGVEKL-KDTGYGGLPVANPGTL--------ADMTMPNVTAPGNFAQlasayaaKYGVS--REDLKR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 231 LLSHTRA-NEALAAGRFEAEivpieytvydnetgktsqvrvaaddtIRPNVTLEKLAKL----KPAFLEDggstagnSSQ 305
Cdd:PRK06157 169 AMAHVSVkSHANGARNPKAH--------------------------LRKAVTEEQVLKApmiaGPLGLFD-------CCG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 306 ISDGASAAILARRSWATERGLKPVARFLGTQVAGCEPDEMG---------MGPIYAIPRLYKYVGIG--QKDVDVIELNE 374
Cdd:PRK06157 216 VSDGAAAAIVTTPEIARALGKKDPVYVKALQLAVSNGWELQyngwdgsyfPTTRIAARKAYREAGITdpREELSMAEVHD 295
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 342870877 375 AFASQTLACINKLGL---------------DVD---KVNPNGGAIAIGHPTGATGTRQLATLIAEL-GRRGK 427
Cdd:PRK06157 296 CFSITELVTMEDLGLsergqawrdvldgffDADgglPCQIDGGLKCFGHPIGASGLRMLYEMYLQLlGRAGE 367
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
304-442 |
4.37e-05 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 45.65 E-value: 4.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 304 SQISDGASAAILARRSWATERGLKPV-ARFLGTQVAGC--------EPDEMGMGPIY-AIPRLYKYVGIGQKDVDVIELN 373
Cdd:PTZ00455 256 SQVSDGGAGLVLASEEGLQKMGLSPNdSRLVEIKSLACasgnlyedPPDATRMFTSRaAAQKALSMAGVKPSDLQVAEVH 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 374 EAFASQTLACINKLGL-------DVDK-----------VNPNGGAIAIGHPTGATGTRQlatlIAELGRRGK-EVGVISM 434
Cdd:PTZ00455 336 DCFTIAELLMYEALGIaeyghakDLIRngatalegripVNTGGGLLSFGHPVGATGVKQ----IMEVYRQMKgQCGEYQM 411
|
....*...
gi 342870877 435 CASTGIGV 442
Cdd:PTZ00455 412 KNIPALGA 419
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
306-427 |
5.23e-05 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 45.29 E-value: 5.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 306 ISDGASAAILARRSWATERGLKPV-ARFLGTQVAGCEPDEMGMGPIYAIP---------------------RL-----YK 358
Cdd:PRK06365 225 MSDGAACAILASEDKAFEITDKPVlIKAIGTGSDTLRLADRPFGEVPLLPnespddykdlrypgvhsfragRMaakeaYE 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 359 YVGIGQ--KDVDVIELNEAFASQTLACINKLGL----------DVDK--------VNPNGGAIAIGHPTGATGTRQLATL 418
Cdd:PRK06365 305 MAGITDplNDLDLIELHDAYTSSEIQTYEDLGLckygeggqfiESGKpelpgklpVNPSGGLLAAGHAVGATGIMQAVFM 384
|
....*....
gi 342870877 419 IAELGRRGK 427
Cdd:PRK06365 385 FWQLQGRIK 393
|
|
| PKS_KS |
smart00825 |
Beta-ketoacyl synthase; The structure of beta-ketoacyl synthase is similar to that of the ... |
141-173 |
8.46e-05 |
|
Beta-ketoacyl synthase; The structure of beta-ketoacyl synthase is similar to that of the thiolase family and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.
Pssm-ID: 214836 [Multi-domain] Cd Length: 298 Bit Score: 44.24 E-value: 8.46e-05
10 20 30
....*....|....*....|....*....|....
gi 342870877 141 TVNRQCSSSLQALtHMA-HAIQAGQIDVALAGGV 173
Cdd:smart00825 92 TVDTACSSSLVAL-HLAcQSLRSGECDMALAGGV 124
|
|
| PKS |
cd00833 |
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different ... |
146-173 |
1.09e-04 |
|
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.
Pssm-ID: 238429 [Multi-domain] Cd Length: 421 Bit Score: 44.47 E-value: 1.09e-04
10 20
....*....|....*....|....*....
gi 342870877 146 CSSSLQALtHMA-HAIQAGQIDVALAGGV 173
Cdd:cd00833 170 CSSSLVAL-HLAcQSLRSGECDLALVGGV 197
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
146-176 |
1.09e-04 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 43.78 E-value: 1.09e-04
10 20 30
....*....|....*....|....*....|.
gi 342870877 146 CSSSLQALTHMAHAIQAGQIDVALAGGVESM 176
Cdd:pfam00109 173 CSSSLVAIHAAVQSIRSGEADVALAGGVNLL 203
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
146-173 |
1.42e-04 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 44.48 E-value: 1.42e-04
10 20
....*....|....*....|....*....
gi 342870877 146 CSSSLQALtHMA-HAIQAGQIDVALAGGV 173
Cdd:COG3321 174 CSSSLVAV-HLAcQSLRSGECDLALAGGV 201
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
146-176 |
1.64e-04 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 43.55 E-value: 1.64e-04
10 20 30
....*....|....*....|....*....|.
gi 342870877 146 CSSSLQALTHMAHAIQAGQIDVALAGGVESM 176
Cdd:COG0304 161 CASGAHAIGEAYRLIRRGRADVMIAGGAEAA 191
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
306-446 |
2.08e-04 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 43.48 E-value: 2.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 306 ISDGASAAILARRSWATERGLKPVaRFLGTQVA------GCEPDEMGMGPIYAIPRLYKYVGIGQKDVDVIELNEAFASQ 379
Cdd:PRK06158 208 VTDGAGAVVMVRADRARDLPRPPV-YVLGAAAAtwhrqiSSMPDLTVTAAAESGPRAFAMAGLTPADIDVVELYDAFTIN 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 342870877 380 TLACINKLGLdVDK-------------------VNPNGGAIAIGHP---------------TGATGTRQLATliAELGRR 425
Cdd:PRK06158 287 TILFLEDLGF-CAKgeggafveggriapggrlpVNTNGGGLSCVHPgmyglfllieavrqlRGEAGERQVAG--AEVALA 363
|
170 180
....*....|....*....|.
gi 342870877 426 GKEVGVISMCASTGIGVASAI 446
Cdd:PRK06158 364 HGNGGVLSSQATAILGTAATL 384
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
140-177 |
8.29e-04 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 41.37 E-value: 8.29e-04
10 20 30
....*....|....*....|....*....|....*...
gi 342870877 140 HTVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMS 177
Cdd:cd00834 155 YTVSTACASGAHAIGDAARLIRLGRADVVIAGGAEALI 192
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
361-411 |
6.18e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 38.52 E-value: 6.18e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 342870877 361 GIGQKDVDVIELNEAFASQTLACINKLGL-DVDKVNPNGGAIAiGHPTGATG 411
Cdd:PRK07937 261 GGDAGGVDVAELHAPFTHQELILREALGLgDKTKVNPSGGALA-ANPMFAAG 311
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
141-177 |
7.87e-03 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 38.57 E-value: 7.87e-03
10 20 30
....*....|....*....|....*....|....*..
gi 342870877 141 TVNRQCSSSLQALTHMAHAIQAGQIDVALAGGVESMS 177
Cdd:cd00828 157 TPVGACATALEALDLAVEAIRSGKADIVVVGGVEDPL 193
|
|
| |
