|
Name |
Accession |
Description |
Interval |
E-value |
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
32-407 |
4.24e-164 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 465.80 E-value: 4.24e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 32 VITLAIRTPLTKArKGGMKDT---LLDAIVFK-LLEqvnqKSKLDPQLVEDICLGNVSSAKAAYY-CRAALLAAGYPNTT 106
Cdd:cd00751 1 VIVSAVRTPIGRF-GGALKDVsadDLGAAVIKaLLE----RAGLDPEEVDDVIMGNVLQAGEGQNpARQAALLAGLPESV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 107 AGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMT---------EGGDRLERPFAEEILAANQEARDCMQPMGQT 177
Cdd:cd00751 76 PATTVNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSrapyllpkaRRGGRLGLNTLDGMLDDGLTDPFTGLSMGIT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 178 SENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPDFGd 257
Cdd:cd00751 156 AENVAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVPGRKGPVVVDRDEGPRPDTTLEKLAKLKPAFKKDG- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 258 KSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAF 337
Cdd:cd00751 235 TVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEAF 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 338 ASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:cd00751 315 AAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGGQGAAMVI 384
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
7-407 |
6.43e-149 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 429.95 E-value: 6.43e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 7 SSFVSQLTP-----GQKPLDKITQKNPDDVVITLAIRTPLTKARKGGMKDTLLDAIVFKLLEQVNQKSKLDPQLVEDICL 81
Cdd:PLN02287 19 SSEPSSLSAsacaaGDSAAYHRTTAFGDDVVIVAAYRTPICKAKRGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 82 GNV---SSAKAAYyCRAALLAAGYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLERPFAE 158
Cdd:PLN02287 99 GTVlapGSQRANE-CRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGGVNP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 159 EIlAANQEARDCMQPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKI------DGKDVTLTK 232
Cdd:PLN02287 178 RV-ESFSQAQDCLLPMGITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKIvdpktgEEKPIVISV 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 233 DEGPRWGTTYESLSKIRPAFPDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSI 312
Cdd:PLN02287 257 DDGIRPNTTLADLAKLKPVFKKNG-TTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAV 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 313 AVPKLLSQYNLSIDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRK--AKI 390
Cdd:PLN02287 336 AIPAAVKAAGLELDDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGkdCRF 415
|
410
....*....|....*..
gi 339468718 391 LLTTMCIGTGQGMAGLF 407
Cdd:PLN02287 416 GVVSMCIGTGMGAAAVF 432
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
29-407 |
1.67e-148 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 426.40 E-value: 1.67e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 29 DDVVITLAIRTPLTKARkGGMKDTL---LDAIVFK-LLEqvnqKSKLDPQLVEDICLGNVSSAKAAYYC-RAALLAAGYP 103
Cdd:COG0183 2 REVVIVDAVRTPFGRFG-GALADVRaddLGAAVIKaLLE----RAGLDPEAVDDVILGCVLQAGQGQNPaRQAALLAGLP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 104 NTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMT---------EGGDRLERPFAEEILAANQEARDCMQPM 174
Cdd:COG0183 77 ESVPAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSrapmllpkaRWGYRMNAKLVDPMINPGLTDPYTGLSM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 175 GQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPD 254
Cdd:COG0183 157 GETAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVPDRKGEVVVDRDEGPRPDTTLEKLAKLKPAFKK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 255 FGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELN 334
Cdd:COG0183 237 DG-TVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLIEIN 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 339468718 335 EAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:COG0183 316 EAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCIGGGQGIALII 388
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
36-407 |
9.16e-131 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 381.19 E-value: 9.16e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 36 AIRTPLTKArKGGMKDT----LLDAIVFKLLEqvnqKSKLDPQLVEDICLGNV-SSAKAAYYCRAALLAAGYPNTTAGHS 110
Cdd:TIGR01930 4 AARTPIGKF-GGSLKDVsaedLGAAVIKELLE----RNPLDPELIDDVIFGNVlQAGEQQNIARQAALLAGLPESVPAYT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 111 VNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLERPFAEEILAANQEARDCMQ----------PMGQTSEN 180
Cdd:TIGR01930 79 VNRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRSLRWGVKPGNAELEDARLkdltdantglPMGVTAEN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 181 VGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPDFGdKST 260
Cdd:TIGR01930 159 LAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGRKGPVTVSSDEGIRPNTTLEKLAKLKPAFDPDG-TVT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 261 GGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAFASM 340
Cdd:TIGR01930 238 AGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAFAAQ 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 339468718 341 AVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:TIGR01930 318 VLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGGQGAAVIL 384
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
28-404 |
1.49e-118 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 350.22 E-value: 1.49e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 28 PDDVVITLAIRTPLTKArKGGMKD---TLLDAIVFK-LLEqvnqKSKLDPQLVEDICLGNVSSAKAAYY-CRAALLAAGY 102
Cdd:PRK05790 1 MKDVVIVSAARTPIGKF-GGALKDvsaVELGAIVIKaALE----RAGVPPEQVDEVIMGQVLQAGAGQNpARQAALKAGL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 103 PNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGgdrlerPFAEEILAA-----NQEARDCM------ 171
Cdd:PRK05790 76 PVEVPALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQA------PHVLPGSRWgqkmgDVELVDTMihdglt 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 172 -----QPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKI-DGKDVTLTKDEGPRWGTTYESL 245
Cdd:PRK05790 150 dafngYHMGITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIKQrKGDPVVVDTDEHPRPDTTAESL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 246 SKIRPAFpdfgDKS---TGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYN 322
Cdd:PRK05790 230 AKLRPAF----DKDgtvTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 323 LSIDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQG 402
Cdd:PRK05790 306 WSLADLDLIEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCIGGGQG 385
|
..
gi 339468718 403 MA 404
Cdd:PRK05790 386 VA 387
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
30-407 |
2.10e-111 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 332.35 E-value: 2.10e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLTKARKGGMKDTLLDAIVFKLLEQ-VNQKSKLDPQLVEDICLG----------NVSsakaayycRAALL 98
Cdd:PRK09052 7 DAYIVAATRTPVGKAPRGMFKNTRPDDLLAHVLRSaVAQVPGLDPKLIEDAIVGcampeaeqglNVA--------RIGAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 99 AAGYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTE---GGDRLErpFAEEILAANqEARDCMQPMG 175
Cdd:PRK09052 79 LAGLPNSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMvpmMGNKPS--MSPAIFARD-ENVGIAYGMG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 176 QTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITV----------KIDGKDVTLTKDEGPRWGTTYESL 245
Cdd:PRK09052 156 LTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEIterfpdlatgEVDVKTRTVDLDEGPRADTSLEGL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 246 SKIRPAFPDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSI 325
Cdd:PRK09052 236 AKLKPVFANKG-SVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQAGLKQ 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 326 DDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAG 405
Cdd:PRK09052 315 DDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMCVGTGMGAAG 394
|
..
gi 339468718 406 LF 407
Cdd:PRK09052 395 IF 396
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
30-407 |
1.65e-105 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 317.10 E-value: 1.65e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLTKARKGGMKDTLLDAIVFKLLEQVNQKSKLDPQLVEDICLG--NVSSAKAAYYCRAALLAAGYPNTTA 107
Cdd:PRK07108 3 EAVIVSTARTPLAKSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGcaNPEGATGANIARQIALRAGLPVTVP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 108 GHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLERP-FAEEILAANQEarDCMQPMGQTSENVGADFN 186
Cdd:PRK07108 83 GMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCVQNEMNRHmLREGWLVEHKP--EIYWSMLQTAENVAKRYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 187 ITRESQDRYAAESYRRAEVAQKAGWFADEIAPITV----------KIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPdfG 256
Cdd:PRK07108 161 ISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVtagvadkatgRLFTKEVTVSADEGIRPDTTLEGVSKIRSALP--G 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 257 DKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEA 336
Cdd:PRK07108 239 GVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDIDLWELNEA 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 339468718 337 FASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:PRK07108 319 FAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQGAAGLF 389
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
30-407 |
4.75e-100 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 303.45 E-value: 4.75e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtkARKGGM-KDTLLDAIVFKLLEQVNQKSKLDPQLVEDICLGNVS-SAKAAYYCRAALLAAGYPNTTA 107
Cdd:PRK06205 3 DAVICEPVRTPV--GRFGGAfKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYpNGEAPAIGRVAALDAGLPVTVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 108 GHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESM-------------TEGG-----DRLERpfaeeilaanqeARD 169
Cdd:PRK06205 81 GMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMsnvefyttdmrwgVRGGgvqlhDRLAR------------GRE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 170 CMQP--------MGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKI-DGKDVTLTKDEGPRWGT 240
Cdd:PRK06205 149 TAGGrrfpvpggMIETAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVPQrKGDPTVVDRDEHPRADT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 241 TYESLSKIRP--AFPDFGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLL 318
Cdd:PRK06205 229 TLESLAKLRPimGKQDPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKAL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 319 SQYNLSIDDIDVIELNEAFASMAVYCRDTLKI---DWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTM 395
Cdd:PRK06205 309 ARAGLTLDDIDLIELNEAFAAQVLAVLKEWGFgadDEERLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETM 388
|
410
....*....|..
gi 339468718 396 CIGTGQGMAGLF 407
Cdd:PRK06205 389 CIGGGQGLAAVF 400
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
32-407 |
6.01e-98 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 297.82 E-value: 6.01e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 32 VITLAIRTPLTKARKGGMKDTLLD---AIVFKllEQVNQKSKLDPQlVEDICLGNV--SSAKAAYYCRAALLAAGYPNTT 106
Cdd:PRK07661 5 VIVAGARTPVGKAKKGSLKTVRPDdlgALVVK--ETLKRAGNYEGP-IDDLIIGCAmpEAEQGLNMARNIGALAGLPYTV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 107 AGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEggdrleRPFAEEILAAN----QEARDCMQPMGQTSENVG 182
Cdd:PRK07661 82 PAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSL------VPMMGHVVRPNprlvEAAPEYYMGMGHTAEQVA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 183 ADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITV---------KIDGKDVTLTKDEGPRWGTTYESLSKIRPAFP 253
Cdd:PRK07661 156 VKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVtlrtvgennKLQEETITFSQDEGVRADTTLEILGKLRPAFN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 254 DFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIEL 333
Cdd:PRK07661 236 VKG-SVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFEL 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 339468718 334 NEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:PRK07661 315 NEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVF 388
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
30-404 |
8.62e-95 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 289.93 E-value: 8.62e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtkARKGGMKDTL----LDAIVFKLLEQVNqkSKLDPQLVEDICLG----------NVSsakaayycRA 95
Cdd:PRK09050 3 EAFICDAIRTPI--GRYGGALSSVraddLGAVPLKALMARN--PGVDWEAVDDVIYGcanqagednrNVA--------RM 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 96 ALLAAGYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGgdrlerPF----AEEILAANQEARDC- 170
Cdd:PRK09050 71 SALLAGLPVSVPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRA------PFvmgkADSAFSRQAEIFDTt 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 171 ---------MQ------PMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKI-DGKDVTLTKDE 234
Cdd:PRK09050 145 igwrfvnplMKaqygvdSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIPQkKGDPVVVDRDE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 235 GPRWGTTYESLSKIRPAFPDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAV 314
Cdd:PRK09050 225 HPRPETTLEALAKLKPVFRPDG-TVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPAT 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 315 PKLLSQYNLSIDDIDVIELNEAFASMAVYCRDTLKI--DWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILL 392
Cdd:PRK09050 304 RKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYAL 383
|
410
....*....|..
gi 339468718 393 TTMCIGTGQGMA 404
Cdd:PRK09050 384 CTMCIGVGQGIA 395
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
28-407 |
1.62e-94 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 288.79 E-value: 1.62e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 28 PDDVVITLAIRTPLTKArKGGM-----KDTLLDAIVFKLLEQvnqKSKLDPQLVEDICLGNVSSAKAAYY--CRAALLAA 100
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRS-KGGAfrnvrAEDLSAHLMRSLLAR---NPALDPAEIDDIIWGCVQQTLEQGFniARNAALLA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 101 GYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAE-----SMTEGGD---RLERPFAEeilAANQeardcmq 172
Cdd:PRK08947 77 GIPHSVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEhmghvPMNHGVDfhpGLSKNVAK---AAGM------- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 173 pMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPIT-VKIDGKDVTLTKDEGPRWGTTYESLSKIRPA 251
Cdd:PRK08947 147 -MGLTAEMLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEgHDADGVLKLFDYDEVIRPETTVEALAALRPA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 252 FPDFGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVI 331
Cdd:PRK08947 226 FDPVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVF 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 332 ELNEAFASMAVYCRDTL----KIDwEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:PRK08947 306 ELNEAFAAQSLPCLKDLglldKMD-EKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLGQGIATVF 384
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
30-407 |
4.69e-94 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 287.63 E-value: 4.69e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtKARKGGMKD---TLLDAIVFKlleQVNQKSKLDPQLVEDICLGNV--SSAKAAYYCRAALLAAGYPN 104
Cdd:PRK09051 4 EVVVVSGVRTAI-GTFGGSLKDvapTDLGATVVR---EALARAGVDPDQVGHVVFGHVipTEPRDMYLSRVAAINAGVPQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 105 TTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGgdrlerPFAeeILAANQEAR-------DCM------ 171
Cdd:PRK09051 80 ETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRA------PYL--LPAARWGARmgdaklvDMMvgalhd 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 172 ----QPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSK 247
Cdd:PRK09051 152 pfgtIHMGVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEIKTRKGEVVFDTDEHVRADTTLEDLAK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 248 IRPAFPDFGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDD 327
Cdd:PRK09051 232 LKPVFKKENGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVAD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 328 IDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:PRK09051 312 LDVIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCIGGGQGIAAIF 391
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
30-404 |
4.53e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 273.03 E-value: 4.53e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLTKARKGGMK----DTLLDAIVFKLLEQVNQkskLDPQLVEDICLGNVSSAKAAYY--CRAALLAAGYP 103
Cdd:PRK07851 3 EAVIVSTARSPIGRAFKGSLKdmrpDDLAAQMVRAALDKVPA---LDPTDIDDLMLGCGLPGGEQGFnmARVVAVLLGYD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 104 nTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTE----GGDRLerPFAEEILAANQEAR----------- 168
Cdd:PRK07851 80 -FLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRfakgNSDSL--PDTKNPLFAEAQARtaaraeggaea 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 169 -----------DCMQPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKiDGkdVTLTKDEGPR 237
Cdd:PRK07851 157 whdpredgllpDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLP-DG--TVVSTDDGPR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 238 WGTTYESLSKIRPAF-PDfgDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPK 316
Cdd:PRK07851 234 AGTTYEKVSQLKPVFrPD--GTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVEASKQ 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 317 LLSQYNLSIDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMC 396
Cdd:PRK07851 312 ALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTFGLETMC 391
|
....*...
gi 339468718 397 IGTGQGMA 404
Cdd:PRK07851 392 VGGGQGMA 399
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
30-404 |
7.76e-88 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 272.04 E-value: 7.76e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtkARKGGMKDTLL-DAIVFKLLEQVNQKSKLDPQLVEDICLGNVSSA--KAAYYCRAALLAAGYPNTT 106
Cdd:PRK08131 3 DAYIYDGLRSPF--GRHAGALASVRpDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAgeDSRNVARNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 107 AGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGG---DRLERPFAEEILA---------ANQ--EARDCMQ 172
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPfvmGKAESAFSRDAKVfdttigarfPNPkiVAQYGND 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 173 PMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTL--TKDEGPRWGTTYESLSKIRP 250
Cdd:PRK08131 161 SMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGRKLPPKlvAEDEHPRPSSTVEALTKLKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 251 AFPdfGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDV 330
Cdd:PRK08131 241 LFE--GGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLDDMDI 318
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 339468718 331 IELNEAFASMAVYCRDTLKIDWE--KMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK08131 319 IEINEAFASQVLGCLKGLGVDFDdpRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCIGVGQGLA 394
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
36-404 |
3.56e-85 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 265.21 E-value: 3.56e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 36 AIRTPLTKARKGG-MKDTLLDAIVFKLLEQVNQKSKLDPQLVEDICLGNVSSAKAAYYC--RAALLAAGYPNTTAGHSVN 112
Cdd:PRK08242 9 AVRTPRGKGKKDGsLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGADiaRTAVLAAGLPETVPGVQIN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 113 RFCASGLKAVQDIANQISTGSIEIGLALGAESMTE---GGDRLERPFAEEILAANQeardcMQPMGqtsenVGAD----- 184
Cdd:PRK08242 89 RFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRvpmGSDGGAWAMDPSTNFPTY-----FVPQG-----ISADliatk 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 185 FNITRESQDRYAAESYRRAEVAQKAGWFADEIAPitVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPDFGDKS----- 259
Cdd:PRK08242 159 YGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVP--VKDQNGLTILDHDEHMRPGTTMESLAKLKPSFAMMGEMGgfdav 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 260 ---------------TGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLS 324
Cdd:PRK08242 237 alqkypeverinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKALAKAGLT 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 325 IDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK08242 317 VDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITLCVGGGMGIA 396
|
|
| pcaF |
TIGR02430 |
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, ... |
30-407 |
1.13e-83 |
|
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, an enzyme that acts at the end of pathways for the degradation of protocatechuate (from benzoate and related compounds) and of phenylacetic acid.
Pssm-ID: 131483 Cd Length: 400 Bit Score: 261.26 E-value: 1.13e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtkARKGG----MKDTLLDAIVFKLLEQVNQKskLDPQLVEDICLG--NVSSAKAAYYCRAALLAAGYP 103
Cdd:TIGR02430 2 EAYICDAIRTPI--GRYGGslssVRADDLAAVPIKALLARNPQ--LDWAAIDDVIYGcaNQAGEDNRNVARMAALLAGLP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 104 NTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGgdrlerPF----AEEILAANQEARDC--------- 170
Cdd:TIGR02430 78 VSVPGTTVNRLCGSGLDAIGMAARAIKAGEADLLIAGGVESMSRA------PFvmgkADSAFSRSAKIEDTtigwrfinp 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 171 -------MQPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVK-IDGKDVTLTKDEGPRWGTTY 242
Cdd:TIGR02430 152 lmkalygVDSMPETAENVAEEFGISREDQDAFALRSQQRTAAAQASGFFAEEIVPVVIPqKKGEPTVVDQDEHPRPETTL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 243 ESLSKIRPAFPDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYN 322
Cdd:TIGR02430 232 EGLAKLKPVVRPDG-TVTAGNASGVNDGAAALLLASEEAVQRHGLTPRARILAAATAGVEPRIMGIGPVPATQKLLARAG 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 323 LSIDDIDVIELNEAFASMAVYCRDTLKI--DWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTG 400
Cdd:TIGR02430 311 LSIDQFDVIELNEAFAAQALAVLRELGLadDDARVNPNGGAIALGHPLGASGARLVLTALRQLERSGGRYALCTMCIGVG 390
|
....*..
gi 339468718 401 QGMAGLF 407
Cdd:TIGR02430 391 QGIALAI 397
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
31-404 |
1.07e-82 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 258.81 E-value: 1.07e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 31 VVITLAIRTPLTkARKGGMKDTLLDAIVFKLLEQVNQKSKLDPQLVEDICLGNVSSAKAAYY-CRAALLAAGYPNTTAGH 109
Cdd:PRK06633 5 VYITHAKRTAFG-SFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNpARQTLIHAGIPKEVPGY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 110 SVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGD----RLERPFAEEILAanqearDCMQP-----------M 174
Cdd:PRK06633 84 TINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSLGMHgsyiRAGAKFGDIKMV------DLMQYdgltdvfsgvfM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 175 GQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFpD 254
Cdd:PRK06633 158 GITAENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVTIKKTTSLFDHDETVRPDTSLEILSKLRPAF-D 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 255 FGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELN 334
Cdd:PRK06633 237 KNGVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVN 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 335 EAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK06633 317 EAFAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCIGGGMGMA 386
|
|
| fadA |
TIGR02445 |
fatty oxidation complex, beta subunit FadA; This subunit of the FadBA complex has acetyl-CoA ... |
30-407 |
1.76e-81 |
|
fatty oxidation complex, beta subunit FadA; This subunit of the FadBA complex has acetyl-CoA C-acyltransferase (EC 2.3.1.16) activity, and is also known as beta-ketothiolase and fatty oxidation complex, beta subunit. This protein is almost always located adjacent to FadB (TIGR02437). The FadBA complex is the major complex active for beta-oxidation of fatty acids in E. coli. [Fatty acid and phospholipid metabolism, Degradation]
Pssm-ID: 131498 Cd Length: 385 Bit Score: 255.25 E-value: 1.76e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLTKARKGGMKDTLLDAIVFKLLEQV-NQKSKLDPQLVEDICLGNVSSA--KAAYYCRAALLAAGYPNTT 106
Cdd:TIGR02445 1 DVVIVDFGRTPMGRSKGGAFRNTRAEDLSAHLMSKLlARNPKVDPAEVEDIYWGCVQQTleQGFNIARNAALLAQIPHTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 107 AGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAE-----SMTEGGD---RLERPFAEeilAANQeardcmqpMGQTS 178
Cdd:TIGR02445 81 AAVTVNRLCGSSMQALHDAARAIMTGDADVCLVGGVEhmghvPMMHGVDfhpGMSLHVAK---AAGM--------MGLTA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 179 ENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPIT-VKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPDFGD 257
Cdd:TIGR02445 150 EMLGKMHGISREQQDAFAARSHARAHAATQEGKFKNEIIPTQgHDADGFLKQFDYDEVIRPETTVESLAALRPAFDPKNG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 258 KSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAF 337
Cdd:TIGR02445 230 TVTAGTSSALSDGASAMLVMSEQRANELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELNEAF 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 339468718 338 ASMAVYCRDTL----KIDwEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:TIGR02445 310 AAQALPCLKDLglldKMD-EKVNLNGGAIALGHPLGCSGARISTTLLNLMEQKDATFGLATMCIGLGQGIATVF 382
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
30-404 |
4.48e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 249.42 E-value: 4.48e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtkarkGGMKDTL-------LDAIVFK-LLEQvnqkSKLDPQLVEDICLGNVSSAKAAYY-CRAALLAA 100
Cdd:PRK05656 3 DVVIVAATRTAI-----GSFQGSLanipaveLGAAVIRrLLEQ----TGLDPAQVDEVILGQVLTAGAGQNpARQAAIKA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 101 GYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLerPFAEEIL-AANQEARDCM-------- 171
Cdd:PRK05656 74 GLPHSVPAMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVL--PGARTGLrMGHAQLVDSMitdglwda 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 172 ---QPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITV-KIDGKDVTLTKDEGPRWGTTYESLSK 247
Cdd:PRK05656 152 fndYHMGITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIpQRKGEPLAFATDEQPRAGTTAESLAK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 248 IRPAFPDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDD 327
Cdd:PRK05656 232 LKPAFKKDG-SVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAE 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 339468718 328 IDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK05656 311 LDLIEANEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVA 387
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
29-407 |
7.06e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 248.87 E-value: 7.06e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 29 DDVVITLAIRTPLTKAR-KGGMKDTL----LDAIVFKLLEQVNQKSKLDPQLVEDICLGNVSSAKA--AYYCRAALLAAG 101
Cdd:PRK06445 2 EDVYLVDFARTAFSRFRpKDPQKDVFnnirPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGEnwLYGGRHPIFLAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 102 YPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTeggdRL---ERPFAE---EILAANQEARDCMQ--- 172
Cdd:PRK06445 82 LPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMT----RTpmgDNPHIEpnpKLLTDPKYIEYDLTtgy 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 173 PMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAF 252
Cdd:PRK06445 158 VMGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEVEVEGKKKVVDVDQSVRPDTSLEKLAKLPPAF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 253 PDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIE 332
Cdd:PRK06445 238 KPDG-VITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDIDLWE 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 339468718 333 LNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:PRK06445 317 INEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCVGGGQGGAVVL 391
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
30-400 |
1.12e-77 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 245.77 E-value: 1.12e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLtkarkGGMKDTLLDAIVFKL----LEQVNQKSKLDPQLVEDICLGNVSSAKAAYY-CRAALLAAGYPN 104
Cdd:PLN02644 2 DVCIVGVARTPI-----GGFLGSLSSLSATELgsiaIQAALERAGVDPALVQEVFFGNVLSANLGQApARQAALGAGLPP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 105 TTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEggdrlerpfAEEILAANQ--------EARDCM----- 171
Cdd:PLN02644 77 STICTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSN---------APKYLPEARkgsrlghdTVVDGMlkdgl 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 172 ------QPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITV-KIDGKDVTLT-KDEGPRwGTTYE 243
Cdd:PLN02644 148 wdvyndFGMGVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVpGGRGRPSVIVdKDEGLG-KFDPA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 244 SLSKIRPAFPDFGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNL 323
Cdd:PLN02644 227 KLRKLRPSFKEDGGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGL 306
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 339468718 324 SIDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTG 400
Cdd:PLN02644 307 EASQVDYYEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGICNGGG 383
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
32-406 |
4.60e-74 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 236.53 E-value: 4.60e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 32 VITLAIRTPLTKArkGG----MKDTLLDAIVFKlleQVNQKSKLDPQLVEDICLGNVSSAKAAYY-CRAALLAAGYPNTT 106
Cdd:PRK08235 5 VIVSAARTPFGKF--GGslkdVKATELGGIAIK---EALERANVSAEDVEEVIMGTVLQGGQGQIpSRQAARAAGIPWEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 107 AGHSVNRFCASGLKAVQdIANQ-ISTGSIEIGLALGAESMTEG---------GDRLerpfaeeilaANQEARDCM----- 171
Cdd:PRK08235 80 QTETVNKVCASGLRAVT-LADQiIRAGDASVIVAGGMESMSNApyilpgarwGYRM----------GDNEVIDLMvadgl 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 172 ------QPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVK-IDGKDVTLTKDEGPRWGTTYES 244
Cdd:PRK08235 149 tcafsgVHMGVYGGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIPqRKGDPIVVAKDEAPRKDTTIEK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 245 LSKIRPAFPDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLS 324
Cdd:PRK08235 229 LAKLKPVFDKTG-TITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKT 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 325 IDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK08235 308 VEDIDLFEINEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSGGGQGDA 387
|
..
gi 339468718 405 GL 406
Cdd:PRK08235 388 VL 389
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
27-406 |
3.55e-71 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 229.90 E-value: 3.55e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 27 NPDDVVITLAIRTPLTKARKGGMKDTLLDAIVFK----LLEQVNQKSKLDpqlveDICLGNVS-SAKAAYYCRAALLAAG 101
Cdd:PRK08170 1 MARPVYIVDGARTPFLKARGGPGPFSASDLAVAAgralLNRQPFAPDDLD-----EVILGCAMpSPDEANIARVVALRLG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 102 YPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEG----GDRLERPFAE--------EILAANQEAR- 168
Cdd:PRK08170 76 CGEKVPAWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHApllfSEKMVRWLAGwyaaksigQKLAALGKLRp 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 169 DCMQP----------------MGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFAdEIAPItvkIDGKDVTLTK 232
Cdd:PRK08170 156 SYLAPvigllrgltdpvvglnMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLK-EVVPL---FDRDGKFYDH 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 233 DEGPRWGTTYESLSKIRPAF-PDFGdKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPS 311
Cdd:PRK08170 232 DDGVRPDSSMEKLAKLKPFFdRPYG-RVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 312 IAVPKLLSQYNLSIDDIDVIELNEAFASMAV----------YCRDTL-------KIDWEKMNVRGGAIALGHPLGCTGAR 374
Cdd:PRK08170 311 HAATPLLQRHGLTLEDLDLWEINEAFAAQVLaclaawadeeYCREQLgldgalgELDRERLNVDGGAIALGHPVGASGAR 390
|
410 420 430
....*....|....*....|....*....|..
gi 339468718 375 QIVTGLSECRRRKAKILLTTMCIGTGQGMAGL 406
Cdd:PRK08170 391 IVLHLLHALKRRGTKRGIAAICIGGGQGGAML 422
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
32-398 |
9.21e-71 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 227.68 E-value: 9.21e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 32 VITLAIRTPLTKaRKG---GMKDT-LLDAIVFKLLEqvnqKSKLDPQLVEDICLGNVSSA--KAAYYCRAALLAAGYPNT 105
Cdd:PRK07850 5 VIVEAVRTPIGK-RNGwlsGLHAAeLLGAVQRAVLD----RAGIDPGDVEQVIGGCVTQAgeQSNNITRTAWLHAGLPYH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 106 TAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTE------GGDRLERPFAEE--ILAANQ-EArdcmqpmgq 176
Cdd:PRK07850 80 VGATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRvplganAGPGRGLPRPDSwdIDMPNQfEA--------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 177 tSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKI-------DGKDVTLTKDEGPRwGTTYESLSKIR 249
Cdd:PRK07850 151 -AERIAKRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVldeegqpTGETRLVTRDQGLR-DTTMEGLAGLK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 250 PAFPdfGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDID 329
Cdd:PRK07850 229 PVLE--GGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDID 306
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 339468718 330 VIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIG 398
Cdd:PRK07850 307 LVEINEAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAG 375
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
31-280 |
1.81e-69 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 219.87 E-value: 1.81e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 31 VVITLAIRTPLTKArKGGMKDTLLDAIVFKLLEQVNQKSKLDPQLVEDICLGNVSSA-KAAYYCRAALLAAGYPNTTAGH 109
Cdd:pfam00108 1 VVIVSAARTPFGSF-GGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAgEGQNPARQAALKAGIPDSAPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 110 SVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLERPFAEEILAANQEARDCMQP-----------MGQTS 178
Cdd:pfam00108 80 TINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDARSGLKHGDEKKHDLLIPdgltdafngyhMGLTA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 179 ENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTYESLSKIRPAFPDFGdK 258
Cdd:pfam00108 160 ENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGKPTVDKDEGIRPPTTAEPLAKLKPAFDKEG-T 238
|
250 260
....*....|....*....|..
gi 339468718 259 STGGNSSQVTDGAAAVLLMKRS 280
Cdd:pfam00108 239 VTAGNASPINDGAAAVLLMSES 260
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
27-404 |
4.56e-69 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 224.48 E-value: 4.56e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 27 NPDDVVITLAIRTPLTKARKG--GMKDTLLDAIVFK-LLeqvnQKSKLDPQLVEDICLGNV-SSAKAAYYCRAALLAAGY 102
Cdd:PRK08963 3 QGDRIAIVSGLRTPFAKQATAfhGIPAVDLGKMVVGeLL----ARSEIDPELIEQLVFGQVvQMPEAPNIAREIVLGTGM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 103 PNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLERPFAEEILAANQ--------------EAR 168
Cdd:PRK08963 79 NVHTDAYSVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVSKKLARALVDLNKartlgqrlklfsrlRLR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 169 DCM-QP-----------MGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIapITVKIDGKDVTLTKDEGP 236
Cdd:PRK08963 159 DLLpVPpavaeystglrMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEV--MTAHVPPYKQPLEEDNNI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 237 RWGTTYESLSKIRPAFpdfgDKSTG----GNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRI-MGIGPS 311
Cdd:PRK08963 237 RGDSTLEDYAKLRPAF----DRKHGtvtaANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVWQdMLLGPA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 312 IAVPKLLSQYNLSIDDIDVIELNEAFASMAV----------YCRDTL-------KIDWEKMNVRGGAIALGHPLGCTGAR 374
Cdd:PRK08963 313 YATPLALERAGLTLADLTLIDMHEAFAAQTLanlqmfaserFAREKLgrsqaigEVDMSKFNVLGGSIAYGHPFAATGAR 392
|
410 420 430
....*....|....*....|....*....|
gi 339468718 375 QIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK08963 393 MITQTLHELRRRGGGLGLTTACAAGGLGAA 422
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
30-402 |
1.05e-68 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 222.19 E-value: 1.05e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTPLTKARKG--GMKDTLLDAivfKLLEQVNQKSKLDPQLVEDICLGNVSSA--------KAAYycraallA 99
Cdd:PRK06366 3 DVYIVSAKRTAIGKFGRSfsKIKAPQLGG---AAIKAVIDDAKLDPALVQEVIMGNVIQAgvgqnpagQAAY-------H 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 100 AGYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDRLERPF---AEEILAANQEARDCM----- 171
Cdd:PRK06366 73 AGLPFGVTKYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLLPSDLrwgPKHLLHKNYKIDDAMlvdgl 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 172 ------QPMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITvkidgkdvTLTKDEGPRwGTTYESL 245
Cdd:PRK06366 153 idafyfEHMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFN--------DLDRDEGIR-KTTMEDL 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 246 SKIRPAFpdfgDKS---TGGNSSQVTDGAAAvLLMKRSKAL-ELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQY 321
Cdd:PRK06366 224 AKLPPAF----DKNgilTAGNSAQLSDGGSA-LVMASEKAInEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQ 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 322 NLSIDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQ 401
Cdd:PRK06366 299 NKSIDYYDLVEHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLCHGGGG 378
|
.
gi 339468718 402 G 402
Cdd:PRK06366 379 A 379
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
32-407 |
2.38e-68 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 220.41 E-value: 2.38e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 32 VITLAIRTPLTKaRKGGMKDTLLDAIVFKLLEQVnqkSKLDPQLVEDICLGNVSsAKAAYYCRAALLAAGYPNTTAGHSV 111
Cdd:PRK06690 4 VIVEAKRTPIGK-KNGMLKDYEVQQLAAPLLTFL---SKGMEREIDDVILGNVV-GPGGNVARLSALEAGLGLHIPGVTI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 112 NRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGgdrlerPFAEEILAANQEARDcmQPMGQTSENVGADFNITRES 191
Cdd:PRK06690 79 DRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTS------PFQNRARFSPETIGD--PDMGVAAEYVAERYNITREM 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 192 QDRYAAESYRRAEVAQKAGWFADEIAPItvkiDGkdvtlTKDEGPRWGTTYESL-SKIRPAFPDFGdKSTGGNSSQVTDG 270
Cdd:PRK06690 151 QDEYACLSYKRTLQALEKGYIHEEILSF----NG-----LLDESIKKEMNYERIiKRTKPAFLHNG-TVTAGNSCGVNDG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 271 AAAVLLMKRSKALELG-QPILaKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAFASMAVYCRDTLK 349
Cdd:PRK06690 221 ACAVLVMEEGQARKLGyKPVL-RFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAFASKVVACAKELQ 299
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 339468718 350 IDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLF 407
Cdd:PRK06690 300 IPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLF 357
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
29-404 |
2.25e-64 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 211.29 E-value: 2.25e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 29 DDVVITLAIRTPLTkARKGGMKDTLLDAIVFKLLEQVNQKSKLDPQLVEDICLGNVSSA-KAAYYCRAALLAAGYPNTTA 107
Cdd:PRK06954 7 DPIVIASAARTPMA-AFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAgQGQAPARQAALGAGLPLSVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 108 GHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMT---------EGGDRLERP--FAEEILAANQEARDCMQPMGQ 176
Cdd:PRK06954 86 CTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTnapyllpkaRGGMRMGHGqvLDHMFLDGLEDAYDKGRLMGT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 177 TSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKIDGKDVTLTKDEGPRWGTTyESLSKIRPAFPDFG 256
Cdd:PRK06954 166 FAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTVAGKKGDTVIDRDEQPFKANP-EKIPTLKPAFSKTG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 257 dKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEA 336
Cdd:PRK06954 245 -TVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEINEA 323
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 339468718 337 FASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMA 404
Cdd:PRK06954 324 FAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATA 391
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
33-401 |
8.69e-64 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 209.18 E-value: 8.69e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 33 ITLAIRTPLTKaRKGGMKD---TLLDAIVFK-LLEQVNqkskLDPQLVEDICLGNVSS--AKAAYYCRAALLAAGYPNTT 106
Cdd:PRK07801 6 IVDAVRTPVGK-RKGGLAGvhpADLGAHVLKgLVDRTG----IDPAAVDDVIFGCVDTigPQAGNIARTSWLAAGLPEEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 107 AGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTE---------GGDR-LERPFAEeilAANQEARDCMQPMGQ 176
Cdd:PRK07801 81 PGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQipissamtaGEQLgFTSPFAE---SKGWLHRYGDQEVSQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 177 --TSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITvkidgkdvTLTKDEGPRwGTTYESLSKIRPAFPd 254
Cdd:PRK07801 158 frGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVG--------GVTVDEGPR-ETSLEKMAGLKPLVE- 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 255 fGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELN 334
Cdd:PRK07801 228 -GGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDDIDVVEIN 306
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 339468718 335 EAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQ 401
Cdd:PRK07801 307 EAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEGGGT 373
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
33-412 |
1.14e-61 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 204.19 E-value: 1.14e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 33 ITLAIRTplTKARKGG---------MKDTLLDAIVfklleqvnQKSKLDPQLVEDICLGNVSSA--KAAYYCRAALLAAG 101
Cdd:PRK06504 6 IVAAART--AGGRKGGrlagwhpadLAAQVLDALV--------DRSGADPALIEDVIMGCVSQVgeQATNVARNAVLASK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 102 YPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTE--GGDRLERPFAEEI---LAANQEARdcmQPMGQ 176
Cdd:PRK06504 76 LPESVPGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRvpMGSPSTLPAKNGLghyKSPGMEER---YPGIQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 177 TSENVGAD-----FNITRESQDRYAAESYRRAEVAQKAGWFADEIAPITVKI-DGKDVTLTKDEGPRWGTTYESLSKIRP 250
Cdd:PRK06504 153 FSQFTGAEmmakkYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRaDGSGEMHTVDEGIRFDATLEGIAGVKL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 251 AFPdfGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDV 330
Cdd:PRK06504 233 IAE--GGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 331 IELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKILLTTMCigTGQGMAGLFVNE 410
Cdd:PRK06504 311 YEVNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMC--EGGGMANVTIVE 388
|
..
gi 339468718 411 QL 412
Cdd:PRK06504 389 RL 390
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
30-404 |
6.20e-58 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 194.99 E-value: 6.20e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 30 DVVITLAIRTP--LTKARKGGMKD---TLLDAIVFKLLEQVNqksKLDPQLVEDICLGNVSS--AKAAYYCRAALLAAGY 102
Cdd:PRK06025 3 EAYIIDAVRTPrgIGKVGKGALAHlhpQHLAATVLKALAERN---GLNTADVDDIIWSTSSQrgKQGGDLGRMAALDAGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 103 PNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEGGDrlerpfaeeilAANQEARDCMQPMG------- 175
Cdd:PRK06025 80 DIKASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSYTAA-----------MAAEDMAAGKPPLGmgsgnlr 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 176 ------QTSENVGADF-----NITRESQDRYAAESYRRAEVAQKAGWFADEIAPitVKIDGKDVTLTKDEGPRWGTTYES 244
Cdd:PRK06025 149 lralhpQSHQGVCGDAiatmeGITREALDALGLESQRRAARAIKEGRFDKSLVP--VYRDDGSVALDHEEFPRPQTTAEG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 245 LSKIRPAFP-----DFGDKST--------------------GGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVA 299
Cdd:PRK06025 227 LAALKPAFTaiadyPLDDKGTtyrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANM 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 300 GLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAFASMAV-YCRDtLKIDWEKMNVRGGAIALGHPLGCTGARQIVT 378
Cdd:PRK06025 307 GDDPTLMLNAPVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEkFIRD-LDLDRDKVNVNGGAIALGHPIGATGSILIGT 385
|
410 420
....*....|....*....|....*.
gi 339468718 379 GLSECRRRKAKILLTTMCigTGQGMA 404
Cdd:PRK06025 386 VLDELERRGLKRGLVTMC--AAGGMA 409
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
287-408 |
2.15e-48 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 160.89 E-value: 2.15e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 287 QPILAKYVGATVAGLAPRIMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAFASMAVYCRDTLKIDWEKMNVRGGAIALGH 366
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 339468718 367 PLGCTGARQIVTGLSECRRRKAKILLTTMCIGTGQGMAGLFV 408
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIE 122
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
94-404 |
8.71e-48 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 168.54 E-value: 8.71e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 94 RAALLAAGYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAES-------MTEG--------------GDRL 152
Cdd:PRK09268 72 RECVLGSALSPYTPAYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTtsdapiaVNEGlrkillelnrakttGDRL 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 153 E-----RP--FAEEIlAANQEARDCMQpMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFADEIAPItvkidg 225
Cdd:PRK09268 152 KalgklRPkhLAPEI-PRNGEPRTGLS-MGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPF------ 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 226 kdVTLTKDEGPRWGTTYESLSKIRPAFpDFGDKS--TGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGATVA---- 299
Cdd:PRK09268 224 --LGLTRDNNLRPDSSLEKLAKLKPVF-GKGGRAtmTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAavdf 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 300 -----GLaprIMgiGPSIAVPKLLSQYNLSIDDIDVIELNEAFASM----------AVYCRDTL-------KIDWEKMNV 357
Cdd:PRK09268 301 vhgkeGL---LM--APAYAVPRLLARNGLTLQDFDFYEIHEAFASQvlatlkawedEEYCRERLgldaplgSIDRSKLNV 375
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 339468718 358 RGGAIALGHPLGCTGARqIVTGLsecrrrkAKIL--------LTTMCIGTGQGMA 404
Cdd:PRK09268 376 NGSSLAAGHPFAATGGR-IVATL-------AKLLaekgsgrgLISICAAGGQGVT 422
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
60-404 |
2.32e-41 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 150.72 E-value: 2.32e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 60 KLLEQVNQKSKLDPQLVEDICLGNVSSAKAAYYC-RAALLAAGYPNTTAGHSVNRFCASGLKAVQDIANQISTGSIEIGL 138
Cdd:cd00826 29 KAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCaQQAAMHAGGLQEAPAIGMNNLCGSGLRALALAMQLIAGGDANCIL 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 139 ALGAESMTEGGDRLERPFAEEILAANQEARDCmqpmgqtsenvgadfnitresQDRYAAESYRRAEVAQKAGWFADEIAP 218
Cdd:cd00826 109 AGGFEKMETSAENNAKEKHIDVLINKYGMRAC---------------------PDAFALAGQAGAEAAEKDGRFKDEFAK 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 219 ITVKIDGKDVTLTKDEGPRWGTTY--ESLSKIRPAFpDFGDKSTGGNSSQVTDGAAAVLLMKRSKALELGQPILAKYVGA 296
Cdd:cd00826 168 FGVKGRKGDIHSDADEYIQFGDEAslDEIAKLRPAF-DKEDFLTAGNACGLNDGAAAAILMSEAEAQKHGLQSKAREIQA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 297 -------TVAGLAPR----IMGIGPSIAVPKLLSQYNLSIDDIDVIELNEAFASMAVYCRDTLKIDWEK----------- 354
Cdd:cd00826 247 lemitdmASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDLIEAHDAFAANACATNEALGLCPEGqggalvdrgdn 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 339468718 355 -------MNVRGGAIALGHPLGCTGARQIVTGLSECRRRKAKIL-----LTTMCIGTGQGMA 404
Cdd:cd00826 327 tyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRQgagagLALLCIGGGGGAA 388
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
69-377 |
1.92e-11 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 64.98 E-value: 1.92e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 69 SKLDPQLVEDICLGNVSSAkAAYYCRAALLA--AGYPNTTAgHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMT 146
Cdd:cd00829 31 AGLEPADIDAVVVGNAAGG-RFQSFPGALIAeyLGLLGKPA-TRVEAAGASGSAAVRAAAAAIASGLADVVLVVGAEKMS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 147 EGGDRLErPFAeeiLAANQEARDCMQPMGQTSENVGA--------DFNITRESQDRYAAESYRRAEVAQKAgWFADEIap 218
Cdd:cd00829 109 DVPTGDE-AGG---RASDLEWEGPEPPGGLTPPALYAlaarrymhRYGTTREDLAKVAVKNHRNAARNPYA-QFRKPI-- 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 219 itvkidgkdvTLTKDEGPRWGTTYESLskirpafPDFgdkstggnsSQVTDGAAAVLLMKRSKALELG-QPILAKYVGAT 297
Cdd:cd00829 182 ----------TVEDVLNSRMIADPLRL-------LDC---------CPVSDGAAAVVLASEERARELTdRPVWILGVGAA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 298 V--AGLAPRIMGIGPS---IAVPKLLSQYNLSIDDIDVIELNEAFASMAV-------YCRD------------TLKIDWe 353
Cdd:cd00829 236 SdtPSLSERDDFLSLDaarLAARRAYKMAGITPDDIDVAELYDCFTIAELlaledlgFCEKgeggklvregdtAIGGDL- 314
|
330 340
....*....|....*....|....
gi 339468718 354 KMNVRGGAIALGHPLGCTGARQIV 377
Cdd:cd00829 315 PVNTSGGLLSKGHPLGATGLAQAV 338
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
95-377 |
2.34e-08 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 55.67 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 95 AALLA--AGYPNTTAgHSVNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEggdrLERPFAEEIL--AANQEardc 170
Cdd:PRK06064 64 AALIAdyAGLAPIPA-TRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKMTD----VPTPDATEAIarAGDYE---- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 171 mqpmgqTSENVGADFN-----ITRESQDRYAAESYRRAEVAQKAGWFA--DEIAPITVKIDGKDVtltkdegprwgttye 243
Cdd:PRK06064 135 ------WEEFFGATFPglyalIARRYMHKYGTTEEDLALVAVKNHYNGskNPYAQFQKEITVEQV--------------- 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 244 sLSKIRPAFP----DfgdkstggnSSQVTDGAAAVLLMKRSKALELGQP---ILAKYVGATVAGLAPR--IMGIGPS-IA 313
Cdd:PRK06064 194 -LNSPPVADPlkllD---------CSPITDGAAAVILASEEKAKEYTDTpvwIKASGQASDTIALHDRkdFTTLDAAvVA 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 314 VPKLLSQYNLSIDDIDVIELNEAFASMAV-------YCR----------DTLKIDWE-KMNVRGGAIALGHPLGCTGARQ 375
Cdd:PRK06064 264 AEKAYKMAGIEPKDIDVAEVHDCFTIAEIlayedlgFAKkgeggklareGQTYIGGDiPVNPSGGLKAKGHPVGATGVSQ 343
|
..
gi 339468718 376 IV 377
Cdd:PRK06064 344 AV 345
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
6-376 |
2.37e-05 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 46.42 E-value: 2.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 6 ISSFVSQLTPgqkplDKITQKNPD-DVVITLAIRTPLTKARKGGMKDTLLD---AIVFKLL------EQVNQKSKLDPQL 75
Cdd:PTZ00455 21 ITPFVGKGSP-----LFIDKKHPDfGKKENKTLEELLATAIQGTLENTGLDgkaALVDKVVvgnflgELFSSQGHLGPAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 76 VEDICLGNVSSA---KAAYYCRAAllaagypnttaghsvnrfCASGLKAVQDIANQISTGSIEIGLALGAESMT-----E 147
Cdd:PTZ00455 96 VGSLGQSGASNAllyKPAMRVEGA------------------CASGGLAVQSAWEALLAGTSDIALVVGVEVQTtvsarV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 148 GGDRLERpfaeeilAAN---QEARD-----CMqpMGQTSENVGADFNITRESQDRYAAESYRRAEVAQKAGWFadeiapi 219
Cdd:PTZ00455 158 GGDYLAR-------AADyrrQRKLDdftfpCL--FAKRMKYIQEHGHFTMEDTARVAAKAYANGNKNPLAHMH------- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 220 TVKIDGKDVTLTKDEGPRWgttyesLSKirPAFPDFGDKStggNSSQVTDGAAAVLLMKRSKALELG------QPILAKY 293
Cdd:PTZ00455 222 TRKLSLEFCTGASDKNPKF------LGN--ETYKPFLRMT---DCSQVSDGGAGLVLASEEGLQKMGlspndsRLVEIKS 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 294 VGATVAGL---APRIMGIGPS-IAVPKLLSQYNLSIDDIDVIELNEAF--ASMAVY----------------CRDTLKID 351
Cdd:PTZ00455 291 LACASGNLyedPPDATRMFTSrAAAQKALSMAGVKPSDLQVAEVHDCFtiAELLMYealgiaeyghakdlirNGATALEG 370
|
410 420
....*....|....*....|....*
gi 339468718 352 WEKMNVRGGAIALGHPLGCTGARQI 376
Cdd:PTZ00455 371 RIPVNTGGGLLSFGHPVGATGVKQI 395
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
115-374 |
3.75e-05 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 45.45 E-value: 3.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 115 CASGLKAVQDIANQISTGSIEIGLALGAESM-TEGGDRlerpfAEEILAA----NQEARDCMQP----MGQTSENVGADF 185
Cdd:PRK06289 90 CASGSVATLAAMADLRAGRYDVALVVGVELMkTVPGDV-----AAEHLGAaawtGHEGQDARFPwpsmFARVADEYDRRY 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 186 NITRESQDRYAAESY---RRAEVAQKAGW-FADEIApitvkiDGKDVTLTKDEGPrwgttyesLSKIrpafpdfgdkstg 261
Cdd:PRK06289 165 GLDEEHLRAIAEINFanaRRNPNAQTRGWaFPDEAT------NDDDATNPVVEGR--------LRRQ------------- 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 262 gNSSQVTDGAAAVLLMKRSKALELGQ--PIlakyvgATVAGLAPRIMGIG---------------PSI--AVPKLLSQYN 322
Cdd:PRK06289 218 -DCSQVTDGGAGVVLASDAYLRDYADarPI------PRIKGWGHRTAPLGleqkldrsagdpyvlPHVrqAVLDAYRRAG 290
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 323 LSIDDIDVIELNEAFASMAVYCRDTLKI-----DWE-------------KMNVRGGAIALGHPLGCTGAR 374
Cdd:PRK06289 291 VGLDDLDGFEVHDCFTPSEYLAIDHIGLtgpgeSWKaiengeiaiggrlPINPSGGLIGGGHPVGASGVR 360
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
111-376 |
9.56e-04 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 40.98 E-value: 9.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 111 VNRFCASGLKAVQDIANQISTGSIEIGLALGAESMTEggdrLERPFAeeiLAanqeardcmqpMGQTSENVGADFNITRE 190
Cdd:PRK12578 78 VEAMCATGLAASLTAYTAVASGLVDMAIAVGVDKMTE----VDTSTS---LA-----------IGGRGGNYQWEYHFYGT 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 191 SQDRYAAeSYRRAEVAqKAGWFADEIAPITVKIDgKDVTLTKDEGPRWGTTYESLSKIRP-AFP-DFGDkstggnSSQVT 268
Cdd:PRK12578 140 TFPTYYA-LYATRHMA-VYGTTEEQMALVSVKAH-KYGAMNPKAHFQKPVTVEEVLKSRAiSWPiKLLD------SCPIS 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339468718 269 DGAAAVLLMKRSKALELG--QPILAKYVG--ATVAGLAPRIMGIG---PSIAVPKLLSQYNLSIDDIDVIELNEAF--AS 339
Cdd:PRK12578 211 DGSATAIFASEEKVKELKidSPVWITGIGyaNDYAYVARRGEWVGfkaTQLAARQAYNMAKVTPNDIEVATVHDAFtiAE 290
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 339468718 340 MAVY-----CR-----------DTLKIDWEKMNVRGGAIALGHPLGCTGARQI 376
Cdd:PRK12578 291 IMGYedlgfTEkgkggkfieegQSEKGGKVGVNLFGGLKAKGHPLGATGLSMI 343
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
270-333 |
4.98e-03 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 38.96 E-value: 4.98e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 339468718 270 GAAAVLLMKRSKALELGQPILAKYVGATVA--GLAPRIMGIGPSIAVPKL--LSQYNLSIDDIDVIEL 333
Cdd:cd00828 232 GAGVLVLERAELALARGAPIYGRVAGTASTtdGAGRSVPAGGKGIARAIRtaLAKAGLSLDDLDVISA 299
|
|
| |
