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Conserved domains on  [gi|291417101|gb|EFE90820|]
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DNA-binding helix-turn-helix protein [Oribacterium sp. oral taxon 078 str. F0262]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
12-71 5.66e-09

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 48.07  E-value: 5.66e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEIL 71
Cdd:COG1396   9 GERLRELRKARGLTQEELAERLG-VSRSTISRIERGRRNPSLETLLKLAKALGVSLDELL 67
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
12-71 5.66e-09

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 48.07  E-value: 5.66e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEIL 71
Cdd:COG1396   9 GERLRELRKARGLTQEELAERLG-VSRSTISRIERGRRNPSLETLLKLAKALGVSLDELL 67
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 12-70 7.40e-08

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 44.47  E-value: 7.40e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEI 70
Cdd:cd00093   1 GERLKELRKEKGLTQEELAEKLG-VSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
14-70 6.94e-07

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 42.12  E-value: 6.94e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 291417101   14 NIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEI 70
Cdd:smart00530  1 RLKELREEKGLTQEELAEKLG-VSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
PHA01976 PHA01976
helix-turn-helix protein
 15-75 4.22e-05

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 38.01  E-value: 4.22e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 291417101 15 IAKLRRERGIRVRDIADFMGFLEPQaVYRWQQGRTLPSLENLYALSLLLSVPMEEILVRSS 75
Cdd:PHA01976  7 LIKARNARAWSAPELSRRAGVRHSL-IYDFEADKRLPNLKTLLRLADALGVTLDWLCGRCG 66
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
12-71 5.66e-09

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 48.07  E-value: 5.66e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEIL 71
Cdd:COG1396   9 GERLRELRKARGLTQEELAERLG-VSRSTISRIERGRRNPSLETLLKLAKALGVSLDELL 67
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
12-71 1.75e-08

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 46.38  E-value: 1.75e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEIL 71
Cdd:COG1476   6 GNRLKELRKERGLTQEELAELLG-VSRQTISAIENGKYNPSLELALKIARALGVSLEELF 64
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 12-70 7.40e-08

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 44.47  E-value: 7.40e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEI 70
Cdd:cd00093   1 GERLKELRKEKGLTQEELAEKLG-VSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
14-70 6.94e-07

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 42.12  E-value: 6.94e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 291417101   14 NIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEEI 70
Cdd:smart00530  1 RLKELREEKGLTQEELAEKLG-VSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
PHA01976 PHA01976
helix-turn-helix protein
 15-75 4.22e-05

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 38.01  E-value: 4.22e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 291417101 15 IAKLRRERGIRVRDIADFMGFLEPQaVYRWQQGRTLPSLENLYALSLLLSVPMEEILVRSS 75
Cdd:PHA01976  7 LIKARNARAWSAPELSRRAGVRHSL-IYDFEADKRLPNLKTLLRLADALGVTLDWLCGRCG 66
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 12-81 5.52e-04

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 35.38  E-value: 5.52e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291417101 12 GRNIAKLRRERGIRVRDIADFMGFLEPQaVYRWQQGRTLPSLENLYALSLLLSVPMEEILVRSSGRAKGL 81
Cdd:COG3620  19 GEALRLMRKELGLSQLPVAELVGVSQSD-ILRIESGKRDPTVSTLEKIAEALGKELSAVLVVDDGKLVGI 87
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 2-69 3.32e-03

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 32.99  E-value: 3.32e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 291417101  2 EYPRIDVKATGRNIAKLRRERGIRVRDIADFMGfLEPQAVYRWQQGRTLPSLENLYALSLLLSVPMEE 69
Cdd:COG1813   4 ESTGELVEDYGERIREAREARGLSQEELAEKLG-VSESTIRRIERGEATPSLDTLRKLEKALGISLAE 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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