NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|288869466|gb|EFD01765|]
View 

putative L-ribulose-5-phosphate 4-epimerase [Hungatella hathewayi DSM 13479]

Protein Classification

class II aldolase/adducin family protein( domain architecture ID 10000749)

class II aldolase/adducin family protein similar to L-fuculose phosphate aldolase, which catalyzes the reversible aldol cleavage of L-fuculose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 1-209 3.41e-50

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


:

Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 161.92  E-value: 3.41e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVcMTPHDTDRFQMSWRDVLVTDLEGNVLEkgPGLKPTSEIEI 80
Cdd:COG0235    2 EEEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFL-ITPSGVDFGELTPEDLVVVDLDGNVVE--GDLKPSSETPL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPV-LTEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKH 159
Cdd:COG0235   79 HLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLeQTEAAAFLGDVPVVPYAGPGTEELAEAIAEALGDRP-AVLLRNH 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 288869466 160 GLITASPfGIWDAVRKNLYVEETAKAYFRMIQLVGIEHVPSIDMDELDRM 209
Cdd:COG0235  158 GVVVWGK-DLAEAFDRAEVLEEAARIQLLALALGGPLVLSDEEIDKLARK 206
 
Name Accession Description Interval E-value
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 1-209 3.41e-50

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 161.92  E-value: 3.41e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVcMTPHDTDRFQMSWRDVLVTDLEGNVLEkgPGLKPTSEIEI 80
Cdd:COG0235    2 EEEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFL-ITPSGVDFGELTPEDLVVVDLDGNVVE--GDLKPSSETPL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPV-LTEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKH 159
Cdd:COG0235   79 HLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLeQTEAAAFLGDVPVVPYAGPGTEELAEAIAEALGDRP-AVLLRNH 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 288869466 160 GLITASPfGIWDAVRKNLYVEETAKAYFRMIQLVGIEHVPSIDMDELDRM 209
Cdd:COG0235  158 GVVVWGK-DLAEAFDRAEVLEEAARIQLLALALGGPLVLSDEEIDKLARK 206
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 7-186 3.07e-41

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 138.06  E-value: 3.07e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466    7 NQVLKQARLAETLGLCQSGGGNFSMIDRESGMVcMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPglKPTSEIEIHLAVYR 86
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLPGDGFL-ITPSGVDFGELTPEDLVVVDLDGNVVEGGL--KPSSETPLHLAIYR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   87 AREDILAVAHTHAPYTSVFAGLSMEVKPVLTE-AMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGVAAVMEKHGLITAS 165
Cdd:pfam00596  78 ARPDAGAVVHTHSPYATALSLAKEGLPPITQEaADFLGGDIPIIPYYTPGTEELGERIAEALGGDRKAVLLRNHGLLVWG 157

                         170       180
                  ....*....|....*....|.
gi 288869466  166 PfGIWDAVRKNLYVEETAKAY 186
Cdd:pfam00596 158 K-TLEEAFYLAEELERAAEIQ 177
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 13-187 7.14e-38

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 129.68  E-value: 7.14e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466    13 ARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPGLKPTSEIEIHLAVYRAREDIL 92
Cdd:smart01007   5 CRLLARRGLVEGTGGNISARVGEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGGPKPSSETPLHLAIYRARPDVG 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466    93 AVAHTHAPYTSVFAGLSMEVKPVLTE--AMTYYGRAPLAPFGTPST------PQLAENIVKTLGEKGvAAVMEKHGLITA 164
Cdd:smart01007  85 AVVHTHSPYATALAALGKPLPLLPTEqaAAFLGGEIPYAPYAGPGTelaeegAELAEALAEALPDRP-AVLLRNHGLLVW 163

                          170       180
                   ....*....|....*....|...
gi 288869466   165 SPfGIWDAVRKNLYVEETAKAYF 187
Cdd:smart01007 164 GK-TLEEAFDLAEELEEAAEIQL 185
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
1-188 4.26e-30

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 110.61  E-value: 4.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPglKPTSEIEI 80
Cdd:PRK06833   2 LLQKEREEIVAYGKKLISSGLTKGTGGNISIFNREQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVEGER--KPSSELDM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVLTEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKHG 160
Cdd:PRK06833  80 HLIFYRNREDINAIVHTHSPYATTLACLGWELPAVHYLIAVAGPNVRCAEYATFGTKELAENAFEAMEDRR-AVLLANHG 158

                        170       180
                 ....*....|....*....|....*...
gi 288869466 161 LITASPfGIWDAVRKNLYVEETAKAYFR 188
Cdd:PRK06833 159 LLAGAN-NLKNAFNIAEEIEFCAEIYYQ 185
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 3-207 9.72e-24

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 93.97  E-value: 9.72e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   3 EEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEkgpGLKPTSEIEIHL 82
Cdd:cd00398    1 EKLKRKIIAACLLLDLYGWVTGTGGNVSARDRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVE---GKKPSSETPLHL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  83 AVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVL--TEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGVAAVM-EKH 159
Cdd:cd00398   78 ALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGhtACAVYFTGDIPCTPYMTPETGEDEIGTQRALGFPNSKAVLlRNH 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 288869466 160 GLITASPfGIWDAVRKNLYVEETAKAYFRMIQLVGieHVPSIDMDELD 207
Cdd:cd00398  158 GLFAWGP-TLDEAFHLAVVLEVAAEIQLKALSMGG--QLPPISLELLN 202
 
Name Accession Description Interval E-value
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 1-209 3.41e-50

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 161.92  E-value: 3.41e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVcMTPHDTDRFQMSWRDVLVTDLEGNVLEkgPGLKPTSEIEI 80
Cdd:COG0235    2 EEEELREELAAAGRRLARRGLVDGTAGNISVRLDDDRFL-ITPSGVDFGELTPEDLVVVDLDGNVVE--GDLKPSSETPL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPV-LTEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKH 159
Cdd:COG0235   79 HLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLeQTEAAAFLGDVPVVPYAGPGTEELAEAIAEALGDRP-AVLLRNH 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 288869466 160 GLITASPfGIWDAVRKNLYVEETAKAYFRMIQLVGIEHVPSIDMDELDRM 209
Cdd:COG0235  158 GVVVWGK-DLAEAFDRAEVLEEAARIQLLALALGGPLVLSDEEIDKLARK 206
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 7-186 3.07e-41

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 138.06  E-value: 3.07e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466    7 NQVLKQARLAETLGLCQSGGGNFSMIDRESGMVcMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPglKPTSEIEIHLAVYR 86
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRLPGDGFL-ITPSGVDFGELTPEDLVVVDLDGNVVEGGL--KPSSETPLHLAIYR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   87 AREDILAVAHTHAPYTSVFAGLSMEVKPVLTE-AMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGVAAVMEKHGLITAS 165
Cdd:pfam00596  78 ARPDAGAVVHTHSPYATALSLAKEGLPPITQEaADFLGGDIPIIPYYTPGTEELGERIAEALGGDRKAVLLRNHGLLVWG 157

                         170       180
                  ....*....|....*....|.
gi 288869466  166 PfGIWDAVRKNLYVEETAKAY 186
Cdd:pfam00596 158 K-TLEEAFYLAEELERAAEIQ 177
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 13-187 7.14e-38

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 129.68  E-value: 7.14e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466    13 ARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPGLKPTSEIEIHLAVYRAREDIL 92
Cdd:smart01007   5 CRLLARRGLVEGTGGNISARVGEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGGPKPSSETPLHLAIYRARPDVG 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466    93 AVAHTHAPYTSVFAGLSMEVKPVLTE--AMTYYGRAPLAPFGTPST------PQLAENIVKTLGEKGvAAVMEKHGLITA 164
Cdd:smart01007  85 AVVHTHSPYATALAALGKPLPLLPTEqaAAFLGGEIPYAPYAGPGTelaeegAELAEALAEALPDRP-AVLLRNHGLLVW 163

                          170       180
                   ....*....|....*....|...
gi 288869466   165 SPfGIWDAVRKNLYVEETAKAYF 187
Cdd:smart01007 164 GK-TLEEAFDLAEELEEAAEIQL 185
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
1-188 4.26e-30

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 110.61  E-value: 4.26e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPglKPTSEIEI 80
Cdd:PRK06833   2 LLQKEREEIVAYGKKLISSGLTKGTGGNISIFNREQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVEGER--KPSSELDM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVLTEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKHG 160
Cdd:PRK06833  80 HLIFYRNREDINAIVHTHSPYATTLACLGWELPAVHYLIAVAGPNVRCAEYATFGTKELAENAFEAMEDRR-AVLLANHG 158

                        170       180
                 ....*....|....*....|....*...
gi 288869466 161 LITASPfGIWDAVRKNLYVEETAKAYFR 188
Cdd:PRK06833 159 LLAGAN-NLKNAFNIAEEIEFCAEIYYQ 185
PRK08333 PRK08333
aldolase;
5-187 4.12e-29

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 107.22  E-value: 4.12e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   5 IRNQVLKQARLAETLGLCQSGGGNFSMidRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEkgpGLKPTSEIEIHLAV 84
Cdd:PRK08333   4 VKAQLVKYSKLAHERGLTAAFGGNLSI--RVGNLVFIKATGSVMDELTREQVAVIDLNGNQLS---SVRPSSEYRLHLAV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  85 YRAREDILAVAHTHAPYTSVFAGLSMEVKPVLT-EAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKHGLIT 163
Cdd:PRK08333  79 YRNRPDVRAIAHLHPPYSIVASTLLEEELPIITpEAELYLKKIPILPFRPAGSVELAEQVAEAMKEYD-AVIMERHGIVT 157

                        170       180
                 ....*....|....*....|....
gi 288869466 164 ASPfGIWDAVRKNLYVEETAKAYF 187
Cdd:PRK08333 158 VGR-SLREAFYKAELVEESAKLWY 180
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 1-206 3.29e-25

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 98.16  E-value: 3.29e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEkGPgLKPTSEIEI 80
Cdd:PRK06557   7 MVEKLREEVCKLHLELPKYGLVVWTSGNVSARDPGTDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVE-GD-LKPSSDTAS 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVLTeAMT--YYGRAPLAPFGTPSTPQLAENIVKTLGEKGVAAV-ME 157
Cdd:PRK06557  85 HLYVYRHMPDVGGVVHTHSTYATAWAARGEPIPCVLT-AMAdeFGGPIPVGPFALIGDEAIGKGIVETLKGGRSPAVlMQ 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 288869466 158 KHGLITASPfGIWDAVRKNLYVEETAKAYFRMIQLVGIEHVPSIDMDEL 206
Cdd:PRK06557 164 NHGVFTIGK-DAEDAVKAAVMVEEVARTVHIARQLGEPIPIPQEEIDRL 211
araD PRK08193
L-ribulose-5-phosphate 4-epimerase AraD;
1-208 8.87e-25

L-ribulose-5-phosphate 4-epimerase AraD;


Pssm-ID: 236181  Cd Length: 231  Bit Score: 97.21  E-value: 8.87e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLkQARLA-ETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEkgpG-LKPTSEI 78
Cdd:PRK08193   1 MLEDLKQEVL-EANLAlPKHGLVTFTWGNVSAIDRERGLFVIKPSGVDYDKMTAEDMVVVDLEGNVVE---GkLKPSSDT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  79 EIHLAVYRAREDILAVAHTHAPYTSVFAGLSMEVkPVL--TEAMTYYGRAPLAPFGTPStpQLAEN--------IVKTLG 148
Cdd:PRK08193  77 PTHLVLYKAFPEIGGIVHTHSRHATAWAQAGRDI-PALgtTHADYFYGDIPCTRKMTDE--EINGEyewetgkvIVETFE 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 288869466 149 EKG-----VAAVMEK-HGlitasPFgIW-----DAVRKNLYVEETAK-AYF-RMIQlvgiEHVPSIDMDELDR 208
Cdd:PRK08193 154 KRGidpaaVPGVLVHsHG-----PF-TWgkdaeDAVHNAVVLEEVAKmAYFtRQLN----PQLPDMQQTLLDK 216
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 3-207 9.72e-24

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 93.97  E-value: 9.72e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   3 EEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEkgpGLKPTSEIEIHL 82
Cdd:cd00398    1 EKLKRKIIAACLLLDLYGWVTGTGGNVSARDRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVE---GKKPSSETPLHL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  83 AVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVL--TEAMTYYGRAPLAPFGTPSTPQLAENIVKTLGEKGVAAVM-EKH 159
Cdd:cd00398   78 ALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGhtACAVYFTGDIPCTPYMTPETGEDEIGTQRALGFPNSKAVLlRNH 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 288869466 160 GLITASPfGIWDAVRKNLYVEETAKAYFRMIQLVGieHVPSIDMDELD 207
Cdd:cd00398  158 GLFAWGP-TLDEAFHLAVVLEVAAEIQLKALSMGG--QLPPISLELLN 202
PRK05874 PRK05874
L-fuculose-phosphate aldolase; Validated
 9-166 9.49e-21

L-fuculose-phosphate aldolase; Validated


Pssm-ID: 102036 [Multi-domain]  Cd Length: 217  Bit Score: 86.24  E-value: 9.49e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   9 VLKQARLAETLGLCQSGGGNFSMiDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPGLKPTSEIEIHLAVYRAR 88
Cdd:PRK05874  11 VLAAAKDMLRRGLVEGTAGNISA-RRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKDGRSPSTELNLHLACYRAF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  89 EDILAVAHTHAPYTSVFAgLSMEVKPVLTEAMTYY--GRAPLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKHGLITASP 166
Cdd:PRK05874  90 DDIGSVIHSHPVWATMFA-VAHEPIPACIDEFAIYcgGDVRCTEYAASGTPEVGRNAVRALEGRA-AALIANHGLVAVGP 167
sgaE PRK12348
L-ribulose-5-phosphate 4-epimerase; Reviewed
 3-184 1.45e-18

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183460  Cd Length: 228  Bit Score: 80.62  E-value: 1.45e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   3 EEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKgpGLKPTSEIEIHL 82
Cdd:PRK12348   2 QKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEG--EYRPSSDTATHL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  83 AVYRAREDILAVAHTHAPYTSVFAGLSMEVkPVL--TEAMTYYGRAPLAPFGTPSTPQ------LAENIVKTLGEKG--- 151
Cdd:PRK12348  80 ELYRRYPSLGGIVHTHSTHATAWAQAGLAI-PALgtTHADYFFGDIPCTRGLSEEEVQgeyelnTGKVIIETLGNAEplh 158

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 288869466 152 -VAAVMEKHGlitasPFGiW-----DAVRKNLYVEETAK 184
Cdd:PRK12348 159 tPGIVVYQHG-----PFA-WgkdahDAVHNAVVMEEVAK 191
PRK06357 PRK06357
hypothetical protein; Provisional
 1-184 1.26e-15

hypothetical protein; Provisional


Pssm-ID: 180541 [Multi-domain]  Cd Length: 216  Bit Score: 72.50  E-value: 1.26e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSM---IDRESGMVCMTP---HDTDRFQMSWRDVLVTDLEGNVLEKGPGlKP 74
Cdd:PRK06357   2 LFQKEREDLAKVVKTMFDRKETNAAGGNISVrmtAEKNKEYIIMTPtlmSEAKLCDLSPYQILVVDLNTGEVIEGVG-RV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  75 TSEIEIHLAVYRAREDILAVAHTHAPYTSVFAGLSMEVkPVLTEAMTYYGRAPLAPFGTPSTPQLAENI---VKTLGEKG 151
Cdd:PRK06357  81 TREINMHEAAYVANPKIKCVYHSHAKESMFWATLGLEM-PNLTEATQKLGKIPTLPFAPATSPELAEIVrkhLIELGDKA 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 288869466 152 V--AAVMEKHGLITAS-----PFGIWDAVRKNLYVEETAK 184
Cdd:PRK06357 160 VpsAFLLNSHGIVITDtslhkAYDILETIEWNAYIAYQAT 199
araD PRK13213
L-ribulose-5-phosphate 4-epimerase; Reviewed
 1-183 8.68e-15

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 106181  Cd Length: 231  Bit Score: 70.53  E-value: 8.68e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLE-GNVLEKGPglKPTSEIE 79
Cdd:PRK13213   1 MLEQLKQQVFEANLALPKYKLVTFTWGNVSGIDREHGLVVIKPSGVEYDVMSVNDMVVVDLAtGKVVEGDK--KPSSDTD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  80 IHLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPV-LTEAMTYYGRAPLAPFGTPS------TPQLAENIVKTLGEKGV 152
Cdd:PRK13213  79 THLVLYRAFAEIGGIVHTHSRHATIWAQAGKSLSALgTTHADYFYGPIPCTRLMTEAeitgdyEHETGKVIVETFAEQGL 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 288869466 153 ------AAVMEKHGlitasPFGiW-----DAVRKNLYVEETA 183
Cdd:PRK13213 159 raadipAVLVNGHG-----PFA-WgsnaaNAVHNAVVLEEIA 194
araD PRK13145
L-ribulose-5-phosphate 4-epimerase; Provisional
 1-205 1.36e-14

L-ribulose-5-phosphate 4-epimerase; Provisional


Pssm-ID: 183870 [Multi-domain]  Cd Length: 234  Bit Score: 69.86  E-value: 1.36e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKgpGLKPTSEIEI 80
Cdd:PRK13145   2 NLQEMRERVCAANKSLPKHGLVKFTWGNVSEVCRELGRIVIKPSGVDYDELTPENMVVTDLDGNVVEG--DLNPSSDLPT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSMEVkPVL--TEAMTYYGRAPLAPFGTPSTPQLAEN------IVKTLGEKGV 152
Cdd:PRK13145  80 HVELYKAWPEVGGIVHTHSTEAVGWAQAGRDI-PFYgtTHADYFYGPIPCARSLTKDEVNGAYEketgsvIIEEFEKRGL 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 288869466 153 ------AAVMEKHGlitasPFGiW-----DAVRKNLYVEETAKAYfRMIQLVG--IEHVPSIDMDE 205
Cdd:PRK13145 159 dpmavpGIVVRNHG-----PFT-WgknpeQAVYHSVVLEEVAKMN-RLTEQINprVEPAPQYIMDK 217
sgbE PRK12347
L-ribulose-5-phosphate 4-epimerase; Reviewed
 1-183 2.62e-14

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183459  Cd Length: 231  Bit Score: 69.08  E-value: 2.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   1 MFEEIRNQVLkQARLA-ETLGLCQSGGGNFSMIDRESGMVCMTPHDTDRFQMSWRDVLVTDLE-GNVLEKGPglKPTSEI 78
Cdd:PRK12347   1 MLEQLKADVL-AANLAlPAHHLVTFTWGNVSAVDETRQLMVIKPSGVEYDVMTADDMVVVEIAsGKVVEGSK--KPSSDT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  79 EIHLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPV-LTEAMTYYGRAPLAPFGTPS------TPQLAENIVKTLGEKG 151
Cdd:PRK12347  78 PTHLALYRRYPEIGGIVHTHSRHATIWSQAGLDLPAWgTTHADYFYGAIPCTRLMTAEeingeyEYQTGEVIIETFEERG 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 288869466 152 V------AAVMEKHGlitasPFGiW-----DAVRKNLYVEETA 183
Cdd:PRK12347 158 IspaqipAVLVHSHG-----PFA-WgknaaDAVHNAVVLEECA 194
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
19-164 4.37e-14

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 68.23  E-value: 4.37e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  19 LGLCQSGGGNFSmIDRESGMVcMTPHDTDRFQMSWRDVLVTDLEGNVLEkgpGLKPTSEIEIHLAVYRAREDILAVAHTH 98
Cdd:PRK08087  20 LGLNQGTAGNVS-VRYQDGML-ITPTGIPYEKLTESHIVFVDGNGKHEE---GKLPSSEWRFHMAAYQTRPDANAVVHNH 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 288869466  99 APYTsvfAGLSMEVKPVltEAMTYYGRA------PLAPFGTPSTPQLAENIVKTLGEKGvAAVMEKHGLITA 164
Cdd:PRK08087  95 AVHC---TAVSILNRPI--PAIHYMIAAaggnsiPCAPYATFGTRELSEHVALALKNRK-ATLLQHHGLIAC 160
PRK08130 PRK08130
putative aldolase; Validated
 14-206 1.85e-13

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 66.44  E-value: 1.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  14 RLAETL---GLCQSGGGNFSMidR-ESGMVCMTPHDTDRFQMSWRDVLVTDLEGNVLEkgpGLKPTSEIEIHLAVYRARE 89
Cdd:PRK08130  12 RLGRSLfqrGYTVGSAGNISA--RlDDGGWLVTPTGSCLGRLDPARLSKVDADGNWLS---GDKPSKEVPLHRAIYRNNP 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  90 DILAVAHTHAPYTsvfAGLSM-------EVKPVLTeamTYY----GRAPLAPFGTPSTPQLAENIVKTLGEkgVAAVM-E 157
Cdd:PRK08130  87 ECGAVVHLHSTHL---TALSClggldptNVLPPFT---PYYvmrvGHVPLIPYYRPGDPAIAEALAGLAAR--YRAVLlA 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 288869466 158 KHGLITASpfgiwDAVRKNLYV----EETAKAYFrMIQLVGIEHVPSIDMDEL 206
Cdd:PRK08130 159 NHGPVVWG-----SSLEAAVNAteelEETAKLIL-LLGGRPPRYLTDEEIAEL 205
PRK06208 PRK06208
class II aldolase/adducin family protein;
43-166 4.71e-10

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 57.69  E-value: 4.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  43 PHDTDRF----------QMSWRDVLVTDLEGNVLEKGPGLKPTSeIEIHLAVYRAREDILAVAHTHAPYTSVFAGLSMEV 112
Cdd:PRK06208  72 PELPDHFwvnplgvhfsQIKVSDLLLVDHDGEVVEGDRPLNRAA-FAIHSAIHEARPDVVAAAHTHSTYGKAWSTLGRPL 150

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 288869466 113 KPVLTEAMTYYGR-APLAPF-GTPSTPQLAENIVKTLGEKGvAAVMEKHGLITASP 166
Cdd:PRK06208 151 DPITQDACAFYEDhALFDDFtGVVVDTSEGRRIAAALGTHK-AVILQNHGLLTVGP 205
PRK09220 PRK09220
methylthioribulose 1-phosphate dehydratase;
20-113 1.10e-07

methylthioribulose 1-phosphate dehydratase;


Pssm-ID: 236415 [Multi-domain]  Cd Length: 204  Bit Score: 50.32  E-value: 1.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  20 GLCQSGGGNFSMidRESGMVC-MTPHDTDRFQMSWRDVLVTDLEGNVLekGPGLKPTSEIEIHLAVYRAREDILAVAHTH 98
Cdd:PRK09220  21 GWVPATSGNMSV--RLDEQHCaITVSGKDKGSLTAEDFLQVDIAGNAV--PSGRKPSAETLLHTQLYRLFPEIGAVLHTH 96

                         90
                 ....*....|....*
gi 288869466  99 APYTSVfagLSMEVK 113
Cdd:PRK09220  97 SVNATV---LSRVEK 108
PRK08660 PRK08660
aldolase;
76-160 4.06e-07

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 48.41  E-value: 4.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  76 SEIEIHLAVYRaREDILAVAHTHAPYTSVFAGLSMEVKPVLTEAMTYYGRAPLAPfGTPSTPQLAENIVKTLGEKGVaAV 155
Cdd:PRK08660  67 SETPVHRAIYR-RTSAKAIVHAHPPYAVALSLLEDEIVPLDSEGLYFLGTIPVVG-GDIGSGELAENVARALSEHKG-VV 143


                 ....*
gi 288869466 156 MEKHG 160
Cdd:PRK08660 144 VRGHG 148
PRK06486 PRK06486
aldolase;
55-125 1.10e-05

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 45.09  E-value: 1.10e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 288869466  55 DVLVTDLEGNVLEkGPGLKPTSEIEIHLAVYRAREDILAVAHTHAPYTSvfaGLSM-EVKPVLT---EAMTYYGR 125
Cdd:PRK06486  78 DLLICDFDGNVLA-GRGEPEATAFFIHARIHRAIPRAKAAFHTHMPYAT---ALSLtEGRPLTTlgqTALKFYGR 148
PRK06661 PRK06661
hypothetical protein; Provisional
 48-163 2.01e-05

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 44.05  E-value: 2.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  48 RF-QMSWRDVLVTDLEGNVLEKGPGLKPTSEIEIHLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVLTEAMTYYGRA 126
Cdd:PRK06661  45 RFeEVTTENLLKVSLDGQILEGEEYQYNKTGYFIHGSIYKTRPDISAIFHYHTPASIAVSALKCGLLPISQWALHFYDRI 124

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 288869466 127 PLAPFGTPSTPQLAE--NIVKTLGEKGVaAVMEKHGLIT 163
Cdd:PRK06661 125 SYHNYNSLALDADKQssRLVNDLKQNYV-MLLRNHGAIT 162
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 55-184 2.84e-05

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 43.86  E-value: 2.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  55 DVLVTDLEGNVLEkGPGLkPTSEIEIHLAVYRAREDILAVAHTHAPYTsvfAGLSMEVKPVLTEAMTyygrapLAPF--- 131
Cdd:PRK07090  81 NLLLVDEDLNVLD-GEGM-PNPANRFHSWIYRARPDVNCIIHTHPPHV---AALSMLEVPLVVSHMD------TCPLydd 149

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 288869466 132 --------GTPSTPQLAENIVKTLGEKGvAAVMEKHGLITASPfGIWDAVRKNLYVEETAK 184
Cdd:PRK07090 150 caflkdwpGVPVGNEEGEIISAALGDKR-AILLSHHGQLVAGK-SIEEACVLALLIERAAR 208
PRK07490 PRK07490
hypothetical protein; Provisional
 2-186 3.61e-04

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 40.47  E-value: 3.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466   2 FEEIRNQVLKQARLAETLGLCQSGGGNFSMIDRESG-MVCMTPHDTDRFQMSWRDVLVTDLEGNVLEKGPGLKPTSEIEI 80
Cdd:PRK07490   8 EEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGkQFLLNPKWKHFSRIRASDLLLLDADDPSTAERPDVPDATAWAI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 288869466  81 HLAVYRAREDILAVAHTHAPYTSVFAGLSM-EVKPVLTEAMTYYGRAPL-APFGTPSTPQLAENIVKTLGEKGVaAVMEK 158
Cdd:PRK07490  88 HGQIHRRLPHARCVMHVHSVYATALACLADpTLPPIDQNTARFFNRVAVdTLYGGMALEEEGERLAGLLGDKRR-LLMGN 166

                        170       180
                 ....*....|....*....|....*...
gi 288869466 159 HGLITASPfGIWDAVRKNLYVEETAKAY 186
Cdd:PRK07490 167 HGVLVTGD-TVAEAFDDLYYFERACQTY 193
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 60-125 4.85e-03

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 37.13  E-value: 4.85e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 288869466  60 DLEGNVLEKGP-GLKPTSEIeIHLAVYRAREDILAVAHTHAPYTSVFAGLSMEVKPVLTEAMTYYGR 125
Cdd:PRK07044  73 DLDGNVVDDSPyPVNPAGFT-IHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFYGR 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH