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Conserved domains on  [gi|140392041|gb|ECL46064|]
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hypothetical protein GOS_3309958, partial [marine metagenome]

Protein Classification

zinc finger CCHC domain-containing protein( domain architecture ID 10443236)

zinc finger CCHC (ZCCHC) domain-containing protein contains a zinc knuckle or a zinc binding motif, CX2CX4HX4C, where X can be any amino acid, and may bind single-stranded RNA

Gene Ontology:  GO:0008270|GO:0003676
PubMed:  33787465|11179890|12665246

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 234-249 5.14e-08

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


:

Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 47.52  E-value: 5.14e-08
                          10
                  ....*....|....*.
gi 140392041  234 CYNCGEPGHFARDCPN 249
Cdd:pfam00098   3 CYNCGEPGHIARDCPK 18
 
Name Accession Description Interval E-value
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 234-249 5.14e-08

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 47.52  E-value: 5.14e-08
                          10
                  ....*....|....*.
gi 140392041  234 CYNCGEPGHFARDCPN 249
Cdd:pfam00098   3 CYNCGEPGHIARDCPK 18
ZnF_C2HC smart00343
zinc finger;
234-249 1.97e-07

zinc finger;


Pssm-ID: 197667 [Multi-domain]  Cd Length: 17  Bit Score: 45.90  E-value: 1.97e-07
                           10
                   ....*....|....*.
gi 140392041   234 CYNCGEPGHFARDCPN 249
Cdd:smart00343   2 CYNCGKEGHIARDCPS 17
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 234-250 1.43e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 46.72  E-value: 1.43e-06
                         10
                 ....*....|....*..
gi 140392041 234 CYNCGEPGHFARDCPNP 250
Cdd:PTZ00368  30 CYKCGEPGHLSRECPSA 46
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 233-248 3.42e-03

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 37.52  E-value: 3.42e-03
                         10
                 ....*....|....*.
gi 140392041 233 LCYNCGEPGHFARDCP 248
Cdd:COG5082   99 KCYNCGETGHLSRDCN 114
 
Name Accession Description Interval E-value
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 234-249 5.14e-08

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 47.52  E-value: 5.14e-08
                          10
                  ....*....|....*.
gi 140392041  234 CYNCGEPGHFARDCPN 249
Cdd:pfam00098   3 CYNCGEPGHIARDCPK 18
ZnF_C2HC smart00343
zinc finger;
234-249 1.97e-07

zinc finger;


Pssm-ID: 197667 [Multi-domain]  Cd Length: 17  Bit Score: 45.90  E-value: 1.97e-07
                           10
                   ....*....|....*.
gi 140392041   234 CYNCGEPGHFARDCPN 249
Cdd:smart00343   2 CYNCGKEGHIARDCPS 17
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 234-250 1.43e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 46.72  E-value: 1.43e-06
                         10
                 ....*....|....*..
gi 140392041 234 CYNCGEPGHFARDCPNP 250
Cdd:PTZ00368  30 CYKCGEPGHLSRECPSA 46
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 234-250 1.83e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 46.34  E-value: 1.83e-06
                         10
                 ....*....|....*..
gi 140392041 234 CYNCGEPGHFARDCPNP 250
Cdd:PTZ00368  80 CYNCGQTGHISRECPNR 96
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 234-249 4.10e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 45.57  E-value: 4.10e-06
                         10
                 ....*....|....*.
gi 140392041 234 CYNCGEPGHFARDCPN 249
Cdd:PTZ00368  55 CYNCGKTGHLSRECPE 70
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 234-250 7.48e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 44.80  E-value: 7.48e-06
                         10
                 ....*....|....*..
gi 140392041 234 CYNCGEPGHFARDCPNP 250
Cdd:PTZ00368 106 CYNCGGEGHISRDCPNA 122
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 233-248 3.83e-05

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 42.49  E-value: 3.83e-05
                         10
                 ....*....|....*.
gi 140392041 233 LCYNCGEPGHFARDCP 248
Cdd:PTZ00368 131 TCYNCGQTGHLSRDCP 146
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 234-249 3.26e-04

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 39.79  E-value: 3.26e-04
                         10
                 ....*....|....*.
gi 140392041 234 CYNCGEPGHFARDCPN 249
Cdd:PTZ00368   3 CYRCGGVGHQSRECPN 18
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 233-248 3.42e-03

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 37.52  E-value: 3.42e-03
                         10
                 ....*....|....*.
gi 140392041 233 LCYNCGEPGHFARDCP 248
Cdd:COG5082   99 KCYNCGETGHLSRDCN 114
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 234-248 4.27e-03

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 37.14  E-value: 4.27e-03
                         10
                 ....*....|....*
gi 140392041 234 CYNCGEPGHFARDCP 248
Cdd:COG5082   63 CFNCGQNGHLRRDCP 77
zf-CCHC_2 pfam13696
Zinc knuckle; This is a zinc-binding domain of the form CxxCxxxGHxxxxC from a variety of ...
 233-249 6.71e-03

Zinc knuckle; This is a zinc-binding domain of the form CxxCxxxGHxxxxC from a variety of different species.


Pssm-ID: 463959 [Multi-domain]  Cd Length: 21  Bit Score: 33.26  E-value: 6.71e-03
                          10
                  ....*....|....*..
gi 140392041  233 LCYNCGEPGHFARDCPN 249
Cdd:pfam13696   5 VCHICGKKGHYIQDCPT 21
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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