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Conserved domains on  [gi|119616560|gb|EAW96154|]
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C-type lectin domain family 7, member A, isoform CRA_j [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Ly49 super family cl07131
Ly49-like protein, N-terminal region; The sequences making up this family are annotated as, or ...
40-67 3.76e-08

Ly49-like protein, N-terminal region; The sequences making up this family are annotated as, or are similar to, Ly49 receptors. These are type II transmembrane receptors expressed by mouse natural killer (NK) cells. They are classified as being activating (e.g.Ly49D and H) or inhibitory (e.g. Ly49A and G), depending on their effect on NK cell function. They are members of the C-type lectin receptor superfamily, and in fact in many family members this region is found immediately N-terminal to a lectin C-type domain (pfam00059).


The actual alignment was detected with superfamily member pfam08391:

Pssm-ID: 462461 [Multi-domain]  Cd Length: 119  Bit Score: 47.74  E-value: 3.76e-08
                          10        20
                  ....*....|....*....|....*...
gi 119616560   40 SPPWRLIAVILGILCLVILVIAVVLGTM 67
Cdd:pfam08391   1 SVPWHLIVIALGILCSLLLVTVAVLGTK 28
 
Name Accession Description Interval E-value
Ly49 pfam08391
Ly49-like protein, N-terminal region; The sequences making up this family are annotated as, or ...
40-67 3.76e-08

Ly49-like protein, N-terminal region; The sequences making up this family are annotated as, or are similar to, Ly49 receptors. These are type II transmembrane receptors expressed by mouse natural killer (NK) cells. They are classified as being activating (e.g.Ly49D and H) or inhibitory (e.g. Ly49A and G), depending on their effect on NK cell function. They are members of the C-type lectin receptor superfamily, and in fact in many family members this region is found immediately N-terminal to a lectin C-type domain (pfam00059).


Pssm-ID: 462461 [Multi-domain]  Cd Length: 119  Bit Score: 47.74  E-value: 3.76e-08
                          10        20
                  ....*....|....*....|....*...
gi 119616560   40 SPPWRLIAVILGILCLVILVIAVVLGTM 67
Cdd:pfam08391   1 SVPWHLIVIALGILCSLLLVTVAVLGTK 28
 
Name Accession Description Interval E-value
Ly49 pfam08391
Ly49-like protein, N-terminal region; The sequences making up this family are annotated as, or ...
40-67 3.76e-08

Ly49-like protein, N-terminal region; The sequences making up this family are annotated as, or are similar to, Ly49 receptors. These are type II transmembrane receptors expressed by mouse natural killer (NK) cells. They are classified as being activating (e.g.Ly49D and H) or inhibitory (e.g. Ly49A and G), depending on their effect on NK cell function. They are members of the C-type lectin receptor superfamily, and in fact in many family members this region is found immediately N-terminal to a lectin C-type domain (pfam00059).


Pssm-ID: 462461 [Multi-domain]  Cd Length: 119  Bit Score: 47.74  E-value: 3.76e-08
                          10        20
                  ....*....|....*....|....*...
gi 119616560   40 SPPWRLIAVILGILCLVILVIAVVLGTM 67
Cdd:pfam08391   1 SVPWHLIVIALGILCSLLLVTVAVLGTK 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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