|
Name |
Accession |
Description |
Interval |
E-value |
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
1-234 |
4.21e-142 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 397.22 E-value: 4.21e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 1 MADNNAKKEQVHTVFQNISQKYDRLNNIISFEQHKVWRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGL 80
Cdd:PRK00216 3 TVAEEEKQEKVAEMFDSIAPKYDLMNDLLSFGLHRVWRRKTIKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTGEVVGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 81 DFSENMLKVGKEKTSA---MDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQP 157
Cdd:PRK00216 83 DFSEGMLAVGREKLRDlglSGNVEFVQGDAEALPFPDNSFDAVTIAFGLRNVPDIDKALREMYRVLKPGGRLVILEFSKP 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 339894634 158 TMPVFKQVYKLYFRFVMPIFGKLFAKSKEEYEWLQQSTFNFPDKEKLKRLFSQAGFSNIKVRSFTGGVAAMHLGYKE 234
Cdd:PRK00216 163 TNPPLKKAYDFYLFKVLPLIGKLISKNAEAYSYLAESIRAFPDQEELAAMLEEAGFERVRYRNLTGGIVALHVGYKP 239
|
|
| MenG_heptapren |
TIGR02752 |
demethylmenaquinone methyltransferase; MenG is a generic term for a methyltransferase that ... |
6-233 |
6.27e-142 |
|
demethylmenaquinone methyltransferase; MenG is a generic term for a methyltransferase that catalyzes the last step in menaquinone biosynthesis; the exact enzymatic activity differs for different MenG because the menaquinone differ in their prenoid side chains in different species. Members of this MenG protein family are 2-heptaprenyl-1,4-naphthoquinone methyltransferase, and are found together in operons with the two subunits of the heptaprenyl diphosphate synthase in Bacillus subtilis and related species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 131799 Cd Length: 231 Bit Score: 396.48 E-value: 6.27e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 6 AKKEQVHTVFQNISQKYDRLNNIISFEQHKVWRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSEN 85
Cdd:TIGR02752 2 SKEERVHKVFEKIYKKYDRMNSVISFQRHKKWRKDTMKRMNVQAGTSALDVCCGTADWSIALAEAVGPEGHVIGLDFSEN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 86 MLKVGKEKTSA--MDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFK 163
Cdd:TIGR02752 82 MLSVGRQKVKDagLHNVELVHGNAMELPFDDNSFDYVTIGFGLRNVPDYMQVLREMYRVVKPGGKVVCLETSQPTIPGFK 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 164 QVYKLYFRFVMPIFGKLFAKSKEEYEWLQQSTFNFPDKEKLKRLFSQAGFSNIKVRSFTGGVAAMHLGYK 233
Cdd:TIGR02752 162 QLYFFYFKYIMPLFGKLFAKSYKEYSWLQESTRDFPGMDELAEMFQEAGFKDVEVKSYTGGVAAMHMGFK 231
|
|
| MenG_MenH_UbiE |
TIGR01934 |
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ... |
11-233 |
6.63e-118 |
|
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273884 [Multi-domain] Cd Length: 223 Bit Score: 335.39 E-value: 6.63e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 11 VHTVFQNISQKYDRLNNIISFEQHKVWRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLKVG 90
Cdd:TIGR01934 1 VQEMFDRIAPKYDLLNDLLSFGLHRLWRRRAVKLIGVFKGQKVLDVACGTGDLAIELAKSAPDRGKVTGVDFSSEMLEVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 91 KEKTSAMDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFKQVYKLYF 170
Cdd:TIGR01934 81 KKKSELPLNIEFIQADAEALPFEDNSFDAVTIAFGLRNVTDIQKALREMYRVLKPGGRLVILEFSKPANALLKKFYKFYL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 339894634 171 RFVMPIFGKLFAKSKEEYEWLQQSTFNFPDKEKLKRLFSQAGFSNIKVRSFTGGVAAMHLGYK 233
Cdd:TIGR01934 161 KNVLPSIGGLISKNAEAYTYLPESIRAFPSQEELAAMLKEAGFEEVRYRSLTFGVAAIHVGKK 223
|
|
| Ubie_methyltran |
pfam01209 |
ubiE/COQ5 methyltransferase family; |
9-233 |
2.62e-107 |
|
ubiE/COQ5 methyltransferase family;
Pssm-ID: 395966 [Multi-domain] Cd Length: 228 Bit Score: 308.98 E-value: 2.62e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 9 EQVHTVFQNISQKYDRLNNIISFEQHKVWRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLK 88
Cdd:pfam01209 2 QRVGDVFSSVASKYDLMNDVISFGIHRLWKDFTMKCMGVKRGNKFLDVAGGTGDWTFGLSDSAGSSGKVVGLDINENMLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 89 VGKEKT--SAMDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFKQVY 166
Cdd:pfam01209 82 EGEKKAkeEGKYNIEFLQGNAEELPFEDDSFDIVTISFGLRNFPDYLKVLKEAFRVLKPGGRVVCLEFSKPENPLLSQAY 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 339894634 167 KLYFRFVMPIFGKLFAKSKEEYEWLQQSTFNFPDKEKLKRLFSQAGFSNIKVRSFTGGVAAMHLGYK 233
Cdd:pfam01209 162 ELYFKYVMPFMGKMFAKSYKSYQYLQESIRDFPDQKTLASMFEKAGFKSVGYESLTGGIAAIHWGIK 228
|
|
| PLN02233 |
PLN02233 |
ubiquinone biosynthesis methyltransferase |
14-225 |
3.84e-45 |
|
ubiquinone biosynthesis methyltransferase
Pssm-ID: 177877 [Multi-domain] Cd Length: 261 Bit Score: 151.58 E-value: 3.84e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 14 VFQNISQKYDRLNNIISFEQHKVWRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLKVGKEK 93
Cdd:PLN02233 38 LFNRIAPVYDNLNDLLSLGQHRIWKRMAVSWSGAKMGDRVLDLCCGSGDLAFLLSEKVGSDGKVMGLDFSSEQLAVAASR 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 94 -----TSAMDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFKQVYKL 168
Cdd:PLN02233 118 qelkaKSCYKNIEWIEGDATDLPFDDCYFDAITMGYGLRNVVDRLKAMQEMYRVLKPGSRVSILDFNKSTQPFTTSMQEW 197
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 339894634 169 YFRFVMPIFGKLFAKSKeEYEWLQQSTFNFPDKEKLKRLFSQAGFSNIKVRSFTGGV 225
Cdd:PLN02233 198 MIDNVVVPVATGYGLAK-EYEYLKSSINEYLTGEELEKLALEAGFSSAKHYEISGGL 253
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
15-164 |
1.47e-44 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 146.29 E-value: 1.47e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 15 FQNISQKYDRlnniisfeqhkvwRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAvgpNGEVTGLDFSENMLKVGKEKT 94
Cdd:COG2226 1 FDRVAARYDG-------------REALLAALGLRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERA 64
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 339894634 95 SAMD-NVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFKQ 164
Cdd:COG2226 65 AEAGlNVEFVVGDAEDLPFPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELEE 135
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
54-147 |
2.09e-34 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 118.82 E-value: 2.09e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 54 LDVCCGTADWTIALSKAVGpnGEVTGLDFSENMLKVGKEKTSAMD-NVHLVHGDAMHLPFEDDSFDYVTIGFGL--RNVP 130
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERARERAAEAGlNVEFVQGDAEDLPFPDGSFDLVVSSGVLhhLPDP 79
|
90
....*....|....*..
gi 339894634 131 DYLGALKEMHRVLKPGG 147
Cdd:pfam13649 80 DLEAALREIARVLKPGG 96
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
38-222 |
1.38e-29 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 110.80 E-value: 1.38e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 38 RKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLKVGKEKTSA-MDNVHLVHGDAMHLPFEDDS 116
Cdd:PRK08317 8 RARTFELLAVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKERAAGlGPNVEFVRGDADGLPFPDGS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 117 FDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMpVFKQVYKLYFRFVMPIFGKLFAKSkeeyeWLQQstf 196
Cdd:PRK08317 88 FDAVRSDRVLQHLEDPARALAEIARVLRPGGRVVVLDTDWDTL-VWHSGDRALMRKILNFWSDHFADP-----WLGR--- 158
|
170 180
....*....|....*....|....*.
gi 339894634 197 nfpdkeKLKRLFSQAGFSNIKVRSFT 222
Cdd:PRK08317 159 ------RLPGLFREAGLTDIEVEPYT 178
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
54-151 |
9.94e-27 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 98.89 E-value: 9.94e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 54 LDVCCGTADWTIALSKAVGpngEVTGLDFSENMLKVGKEKTSAmDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYL 133
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGA---RVTGVDISPEMLELAREKAPR-EGLTFVVGDAEDLPFPDNSFDLVLSSEVLHHVEDPE 76
|
90
....*....|....*...
gi 339894634 134 GALKEMHRVLKPGGMVVC 151
Cdd:pfam08241 77 RALREIARVLKPGGILII 94
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
37-150 |
5.74e-23 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 90.08 E-value: 5.74e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 37 WRKHVMKEMR--VKKNSVALDVCCGTADWTIALSKAvgpNGEVTGLDFSENMLKVGKEKTSAMdNVHLVHGDAMHLPFED 114
Cdd:COG2227 10 WDRRLAALLArlLPAGGRVLDVGCGTGRLALALARR---GADVTGVDISPEALEIARERAAEL-NVDFVQGDLEDLPLED 85
|
90 100 110
....*....|....*....|....*....|....*.
gi 339894634 115 DSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVV 150
Cdd:COG2227 86 GSFDLVICSEVLEHLPDPAALLRELARLLKPGGLLL 121
|
|
| PLN02232 |
PLN02232 |
ubiquinone biosynthesis methyltransferase |
79-224 |
7.97e-22 |
|
ubiquinone biosynthesis methyltransferase
Pssm-ID: 165876 Cd Length: 160 Bit Score: 88.21 E-value: 7.97e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 79 GLDFSENMLKVGKEKTS-----AMDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLE 153
Cdd:PLN02232 2 GLDFSSEQLAVAATRQSlkarsCYKCIEWIEGDAIDLPFDDCEFDAVTMGYGLRNVVDRLRAMKEMYRVLKPGSRVSILD 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 339894634 154 --TSQPTMPVFKQVYkLYFRFVMPIfGKLFAKSKeEYEWLQQSTFNFPDKEKLKRLFSQAGFSNIKVRSFTGG 224
Cdd:PLN02232 82 fnKSNQSVTTFMQGW-MIDNVVVPV-ATVYDLAK-EYEYLKYSINGYLTGEELETLALEAGFSSACHYEISGG 151
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
48-212 |
1.28e-20 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 84.78 E-value: 1.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 48 KKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLKVGKEKTSAM--DNVHLVHGDAMHLP--FEDDSFDYVTIG 123
Cdd:pfam13847 2 DKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQKLgfDNVEFEQGDIEELPelLEDDKFDVVISN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 124 FGLRNVPDYLGALKEMHRVLKPGGMVVCLEtsqptmPVFKQvyklyfrfvmpifgKLFAKSKEEYEWLQQSTFNFPDKEK 203
Cdd:pfam13847 82 CVLNHIPDPDKVLQEILRVLKPGGRLIISD------PDSLA--------------ELPAHVKEDSTYYAGCVGGAILKKK 141
|
....*....
gi 339894634 204 LKRLFSQAG 212
Cdd:pfam13847 142 LYELLEEAG 150
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
54-151 |
1.90e-18 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 77.86 E-value: 1.90e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 54 LDVCCGTADWTIALskAVGPNGEVTGLDFSENMLKVGKEKTSA--MDNVHLVHGDAMHLPF-EDDSFDYV-TIGFGLRNV 129
Cdd:cd02440 3 LDLGCGTGALALAL--ASGPGARVTGVDISPVALELARKAAAAllADNVEVLKGDAEELPPeADESFDVIiSDPPLHHLV 80
|
90 100
....*....|....*....|..
gi 339894634 130 PDYLGALKEMHRVLKPGGMVVC 151
Cdd:cd02440 81 EDLARFLEEARRLLKPGGVLVL 102
|
|
| BioC |
TIGR02072 |
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ... |
42-222 |
4.48e-18 |
|
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]
Pssm-ID: 273953 [Multi-domain] Cd Length: 240 Bit Score: 80.02 E-value: 4.48e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 42 MKEMRVKKNSVALDVCCGTADWTIALSKAvGPNGEVTGLDFSENMLKVGKEKTSAmdNVHLVHGDAMHLPFEDDSFDYVT 121
Cdd:TIGR02072 27 LKEKGIFIPASVLDIGCGTGYLTRALLKR-FPQAEFIALDISAGMLAQAKTKLSE--NVQFICGDAEKLPLEDSSFDLIV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 122 IGFGLRNVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFKQVYKLY---FRfvmPI--FGKLFAKSKEEYEWLQQS-T 195
Cdd:TIGR02072 104 SNLALQWCDDLSQALSELARVLKPGGLLAFSTFGPGTLHELRQSFGQHglrYL---SLdeLKALLKNSFELLTLEEELiT 180
|
170 180
....*....|....*....|....*..
gi 339894634 196 FNFPDKEKLKRLFSQAGFSNIKVRSFT 222
Cdd:TIGR02072 181 LSFDDPLDVLRHLKKTGANGLSSGRTS 207
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
6-158 |
5.54e-18 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 78.50 E-value: 5.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 6 AKKEQVHTVFQNISQKYD-RLNNIISFEQHKVWRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGpngEVTGLDFSE 84
Cdd:COG4976 2 ALDAYVEALFDQYADSYDaALVEDLGYEAPALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGY---RLTGVDLSE 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 339894634 85 NMLKVGKEKtsaMDNVHLVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVV-CLETSQPT 158
Cdd:COG4976 79 EMLAKAREK---GVYDRLLVADLADLAEPDGRFDLIVAADVLTYLGDLAAVFAGVARALKPGGLFIfSVEDADGS 150
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
53-150 |
4.99e-17 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 73.70 E-value: 4.99e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 53 ALDVCCGTADWTIALSKAVgPNGEVTGLDFSENMLKVGKEKtsaMDNVHLVHGDAMHLPFEDdSFDYVTIGFGLRNVPDY 132
Cdd:COG4106 5 VLDLGCGTGRLTALLAERF-PGARVTGVDLSPEMLARARAR---LPNVRFVVADLRDLDPPE-PFDLVVSNAALHWLPDH 79
|
90
....*....|....*...
gi 339894634 133 LGALKEMHRVLKPGGMVV 150
Cdd:COG4106 80 AALLARLAAALAPGGVLA 97
|
|
| PRK05785 |
PRK05785 |
hypothetical protein; Provisional |
6-218 |
5.09e-17 |
|
hypothetical protein; Provisional
Pssm-ID: 235607 [Multi-domain] Cd Length: 226 Bit Score: 77.04 E-value: 5.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 6 AKKEQVHTVFQNISQKYDRLNNIISFEQHKVWRKHVMKEM--RVKKNSVALDVCCGTADWTIALSKAVgpNGEVTGLDFS 83
Cdd:PRK05785 6 ATWEELQEAYNKIPKAYDRANRFISFNQDVRWRAELVKTIlkYCGRPKKVLDVAAGKGELSYHFKKVF--KYYVVALDYA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 84 ENMLKVGKEKTSAmdnvhlVHGDAMHLPFEDDSFDYVTIGFGLRNVPDYLGALKEMHRVLKPGGMVVCLetSQPTMPVFK 163
Cdd:PRK05785 84 ENMLKMNLVADDK------VVGSFEALPFRDKSFDVVMSSFALHASDNIEKVIAEFTRVSRKQVGFIAM--GKPDNVIKR 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 339894634 164 QVYKLYFRFVMPIFGKLFAKSKEEYEWLQQSTFNFPDKEKLKRLFSQagFSNIKV 218
Cdd:PRK05785 156 KYLSFYLRYIMPYIACLAGAKCRDYKYIYYIYERLPTNSFHREIFEK--YADIKV 208
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
40-150 |
1.30e-15 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 71.50 E-value: 1.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 40 HVMKEMRVKKNSVALDVCCGTADWTIALSKAVGpnGEVTGLDFSENMLKVGKEKTSAM---DNVHLVHGDAMHLPFeDDS 116
Cdd:COG2230 42 LILRKLGLKPGMRVLDIGCGWGGLALYLARRYG--VRVTGVTLSPEQLEYARERAAEAglaDRVEVRLADYRDLPA-DGQ 118
|
90 100 110
....*....|....*....|....*....|....*....
gi 339894634 117 FDYVT-IG----FGLRNVPDYLgalKEMHRVLKPGGMVV 150
Cdd:COG2230 119 FDAIVsIGmfehVGPENYPAYF---AKVARLLKPGGRLL 154
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
54-149 |
1.60e-15 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 69.70 E-value: 1.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 54 LDVCCGTADWTIALSKAVgPNGEVTGLDFSENMLKVGKEKTSA--MDNVHLVHGDAMHLPFEDD-SFDYVTIGFGLRNVP 130
Cdd:pfam08242 1 LEIGCGTGTLLRALLEAL-PGLEYTGLDISPAALEAARERLAAlgLLNAVRVELFQLDLGELDPgSFDVVVASNVLHHLA 79
|
90
....*....|....*....
gi 339894634 131 DYLGALKEMHRVLKPGGMV 149
Cdd:pfam08242 80 DPRAVLRNIRRLLKPGGVL 98
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
46-150 |
7.28e-15 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 70.72 E-value: 7.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 46 RVKKNSVALDVCCGTADWTIALSKAVGpnGEVTGLDFSENMLKVGKEKTSA--MDNVHLVHGDAMHL-PFEDDSFDYVTi 122
Cdd:COG0500 23 RLPKGGRVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARAAKagLGNVEFLVADLAELdPLPAESFDLVV- 99
|
90 100 110
....*....|....*....|....*....|....
gi 339894634 123 gfgLRNV-----PDYL-GALKEMHRVLKPGGMVV 150
Cdd:COG0500 100 ---AFGVlhhlpPEEReALLRELARALKPGGVLL 130
|
|
| PLN02490 |
PLN02490 |
MPBQ/MSBQ methyltransferase |
49-207 |
2.47e-14 |
|
MPBQ/MSBQ methyltransferase
Pssm-ID: 215270 [Multi-domain] Cd Length: 340 Bit Score: 71.08 E-value: 2.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 49 KNSVALDVCCGTADWTIALSKAVGPnGEVTGLDFSENMLKVGKEKtSAMDNVHLVHGDAMHLPFEDDSFD-YVTIGfGLR 127
Cdd:PLN02490 113 RNLKVVDVGGGTGFTTLGIVKHVDA-KNVTILDQSPHQLAKAKQK-EPLKECKIIEGDAEDLPFPTDYADrYVSAG-SIE 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 128 NVPDYLGALKEMHRVLKPGGMVVCLETSQPTMPVfkqvyklyFRFVMPIFgKLFAKSKEEYEWLQQSTFNfpdKEKLKRL 207
Cdd:PLN02490 190 YWPDPQRGIKEAYRVLKIGGKACLIGPVHPTFWL--------SRFFADVW-MLFPKEEEYIEWFTKAGFK---DVKLKRI 257
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
46-150 |
7.28e-14 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 67.28 E-value: 7.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 46 RVKKNSVALDVCCGTAdwTIAL-SKAVGPNgeVTGLDFSENMLKVGKEKTSAM--DNVHLVHGDAMHLPFEDDSFD---- 118
Cdd:COG1041 23 GAKEGDTVLDPFCGTG--TILIeAGLLGRR--VIGSDIDPKMVEGARENLEHYgyEDADVIRGDARDLPLADESVDaivt 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 339894634 119 ------YVTIGFG-LRNVpdYLGALKEMHRVLKPGGMVV 150
Cdd:COG1041 99 dppygrSSKISGEeLLEL--YEKALEEAARVLKPGGRVV 135
|
|
| arsM |
PRK11873 |
arsenite methyltransferase; |
68-147 |
2.78e-13 |
|
arsenite methyltransferase;
Pssm-ID: 237007 [Multi-domain] Cd Length: 272 Bit Score: 67.28 E-value: 2.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 68 SKAVGPNGEVTGLDFSENMLKVGKE--KTSAMDNVHLVHGDAMHLPFEDDSFDyVTIGFGLRN-VPDYLGALKEMHRVLK 144
Cdd:PRK11873 96 ARRVGPTGKVIGVDMTPEMLAKARAnaRKAGYTNVEFRLGEIEALPVADNSVD-VIISNCVINlSPDKERVFKEAFRVLK 174
|
...
gi 339894634 145 PGG 147
Cdd:PRK11873 175 PGG 177
|
|
| Gcd14 |
COG2519 |
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ... |
64-169 |
2.41e-11 |
|
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442009 [Multi-domain] Cd Length: 249 Bit Score: 61.71 E-value: 2.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 64 TIALSKAVGPNGEVTGLDFSENMLKVGK---EKTSAMDNVHLVHGDAMHlPFEDDSFDYVTIgfglrNVPDYLGALKEMH 140
Cdd:COG2519 106 TLALARAVGPEGKVYSYERREDFAEIARknlERFGLPDNVELKLGDIRE-GIDEGDVDAVFL-----DMPDPWEALEAVA 179
|
90 100
....*....|....*....|....*....
gi 339894634 141 RVLKPGGMVVCLetsqptMPVFKQVYKLY 169
Cdd:COG2519 180 KALKPGGVLVAY------VPTVNQVSKLV 202
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
46-216 |
6.45e-11 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 58.98 E-value: 6.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 46 RVKKNSVALDVCCGTADWTIALsKAVGPngEVTGLDFSENMLKVGKEKtsamdNVHLVHgDAMHLPFEDDSFDYVTIGFG 125
Cdd:pfam13489 19 KLPSPGRVLDFGCGTGIFLRLL-RAQGF--SVTGVDPSPIAIERALLN-----VRFDQF-DEQEAAVPAGKFDVIVAREV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 126 LRNVPDYLGALKEMHRVLKPGGMVVCLEtsqPTMPVFKQVYKLYFRFVMPIFGKLfakskeeyewlqqstfNFPDKEKLK 205
Cdd:pfam13489 90 LEHVPDPPALLRQIAALLKPGGLLLLST---PLASDEADRLLLEWPYLRPRNGHI----------------SLFSARSLK 150
|
170
....*....|.
gi 339894634 206 RLFSQAGFSNI 216
Cdd:pfam13489 151 RLLEEAGFEVV 161
|
|
| cbiT |
PRK00377 |
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional |
38-150 |
1.40e-09 |
|
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
Pssm-ID: 234740 Cd Length: 198 Bit Score: 55.96 E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 38 RKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLKVGK---EKTSAMDNVHLVHGDAMHLPFE- 113
Cdd:PRK00377 29 RALALSKLRLRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRrnaEKFGVLNNIVLIKGEAPEILFTi 108
|
90 100 110
....*....|....*....|....*....|....*..
gi 339894634 114 DDSFDYVTIGFGLRNVPDYLGALKEmhrVLKPGGMVV 150
Cdd:PRK00377 109 NEKFDRIFIGGGSEKLKEIISASWE---IIKKGGRIV 142
|
|
| PRK10258 |
PRK10258 |
biotin biosynthesis protein BioC; Provisional |
54-167 |
1.55e-09 |
|
biotin biosynthesis protein BioC; Provisional
Pssm-ID: 182340 [Multi-domain] Cd Length: 251 Bit Score: 56.69 E-value: 1.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 54 LDVCCGTA----DWTIALSkavgpngEVTGLDFSENMLKVGKEKTSAMdnvHLVHGDAMHLPFEDDSFDYVTIGFGLRNV 129
Cdd:PRK10258 47 LDAGCGPGwmsrYWRERGS-------QVTALDLSPPMLAQARQKDAAD---HYLAGDIESLPLATATFDLAWSNLAVQWC 116
|
90 100 110
....*....|....*....|....*....|....*...
gi 339894634 130 PDYLGALKEMHRVLKPGGMVVCLETSQPTMPVFKQVYK 167
Cdd:PRK10258 117 GNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQ 154
|
|
| TrmR |
COG4122 |
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ... |
64-151 |
6.11e-08 |
|
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443298 Cd Length: 173 Bit Score: 50.95 E-value: 6.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 64 TIALSKAVGPNGEVTGLDFSENMLKVGKE---KTSAMDNVHLVHGDAMH-LP-FEDDSFDYVTIGFGLRNVPDYLGALKE 138
Cdd:COG4122 31 TLWLARALPDDGRLTTIEIDPERAAIAREnfaRAGLADRIRLILGDALEvLPrLADGPFDLVFIDADKSNYPDYLELALP 110
|
90
....*....|...
gi 339894634 139 MhrvLKPGGMVVC 151
Cdd:COG4122 111 L---LRPGGLIVA 120
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
43-150 |
3.13e-07 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 50.13 E-value: 3.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 43 KEMRVKKnsvALDVCCGTADWTIALSKAVGPNgeVTGLDFSENMLKVGKEKTSAM---DNVHLVHGDAMHLPFEDDSFDY 119
Cdd:PLN02244 115 DEKRPKR---IVDVGCGIGGSSRYLARKYGAN--VKGITLSPVQAARANALAAAQglsDKVSFQVADALNQPFEDGQFDL 189
|
90 100 110
....*....|....*....|....*....|.
gi 339894634 120 VTIGFGLRNVPDYLGALKEMHRVLKPGGMVV 150
Cdd:PLN02244 190 VWSMESGEHMPDKRKFVQELARVAAPGGRII 220
|
|
| PCMT |
pfam01135 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); |
45-173 |
6.81e-07 |
|
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
Pssm-ID: 395902 [Multi-domain] Cd Length: 205 Bit Score: 48.52 E-value: 6.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 45 MRVKKNSVALDVCCGTADWTIALSKAVGPNGEVTGLDFSENMLKVGKE--KTSAMDNVHLVHGDAmHLPFEDDS-FDYVT 121
Cdd:pfam01135 69 LELKPGMRVLEIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRnlEKLGLENVIVVVGDG-RQGWPEFApYDAIH 147
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 339894634 122 IGFGLRNVPdylgalKEMHRVLKPGGMVVC---LETSQPTM-------PVFKQVYKLYFRFV 173
Cdd:pfam01135 148 VGAAAPEIP------EALIDQLKEGGRLVIpvgPNGNQVLQqfdkrndGSVVIKDLEGVRFV 203
|
|
| COG4627 |
COG4627 |
Predicted SAM-depedendent methyltransferase [General function prediction only]; |
95-151 |
1.59e-06 |
|
Predicted SAM-depedendent methyltransferase [General function prediction only];
Pssm-ID: 443666 [Multi-domain] Cd Length: 161 Bit Score: 46.78 E-value: 1.59e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 339894634 95 SAMDNVHLVHGDAMHLPFEDDSFDYVtigFGlRNV------PDYLGALKEMHRVLKPGGMVVC 151
Cdd:COG4627 25 VPAPGVDIVGDLTDPLPFPDNSVDAI---YS-SHVlehldyEEAPLALKECYRVLKPGGILRI 83
|
|
| COG4798 |
COG4798 |
Predicted methyltransferase [General function prediction only]; |
63-150 |
9.90e-06 |
|
Predicted methyltransferase [General function prediction only];
Pssm-ID: 443826 Cd Length: 274 Bit Score: 45.29 E-value: 9.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 63 WTIALSKAVGPNGEVTGLDF-----SENMLKVGKEKTSA--------MDNVHLVHGDAMHLPFEDD-SFDYVTIGfglRN 128
Cdd:COG4798 80 YTEILAPYLGPKGKVYAANFdpdsePPEYAKRSREAFSAklaadpalYGNVRVTAFAPPDDPIAPPgSADLVLTF---RN 156
|
90 100
....*....|....*....|....*...
gi 339894634 129 VPDYLG------ALKEMHRVLKPGGMVV 150
Cdd:COG4798 157 YHNWYRagdaaaMFAAFFKALKPGGVLG 184
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
38-149 |
2.33e-05 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 44.24 E-value: 2.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 38 RKHVMKEMRVKKNSVALDVCCGtadWTIALSKAVGPNG-EVTGLDFSENMLKVGKEKTSAMDNVHLVHGDAMHLPFEDDS 116
Cdd:pfam02353 50 LDLILDKLGLKPGMTLLDIGCG---WGGLMRRAAERYDvNVVGLTLSKNQYKLARKRVAAEGLARKVEVLLQDYRDFDEP 126
|
90 100 110
....*....|....*....|....*....|....*...
gi 339894634 117 FD-YVTIG----FGLRNVPDYLGALkemHRVLKPGGMV 149
Cdd:pfam02353 127 FDrIVSVGmfehVGHENYDTFFKKL---YNLLPPGGLM 161
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
40-219 |
2.49e-05 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 44.38 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 40 HVMKEMRVKKNSVALDVCCGT---AdwtIALSKAVgPNGEVTGLDFSENMLKVGKE--KTSAMDNVHLVHGDAMHlPFED 114
Cdd:PRK09328 99 WALEALLLKEPLRVLDLGTGSgaiA---LALAKER-PDAEVTAVDISPEALAVARRnaKHGLGARVEFLQGDWFE-PLPG 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 115 DSFD-------YV---TIGFGLRNVPDY--LGAL--------------KEMHRVLKPGGmVVCLETSqptmpvfkqvykl 168
Cdd:PRK09328 174 GRFDlivsnppYIpeaDIHLLQPEVRDHepHLALfggedgldfyrriiEQAPRYLKPGG-WLLLEIG------------- 239
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 339894634 169 yfrfvmpifgklfakskeeyeWLQqstfnfpdKEKLKRLFSQAGFSNIKVR 219
Cdd:PRK09328 240 ---------------------YDQ--------GEAVRALLAAAGFADVETR 261
|
|
| Methyltransf_4 |
pfam02390 |
Putative methyltransferase; This is a family of putative methyltransferases. The aligned ... |
49-149 |
7.60e-05 |
|
Putative methyltransferase; This is a family of putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity.
Pssm-ID: 367068 Cd Length: 173 Bit Score: 41.89 E-value: 7.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 49 KNSVALDVCCGTADWTIALSKAvGPNGEVTGLDFSENML-----KVGKEKTSamdNVHLVHGDAM-HLP--FEDDSFDYV 120
Cdd:pfam02390 1 DAPVFLEIGCGMGGFLVAMAKA-NPDKNFIGIEIRVPGVakalkKIDALGLQ---NLRILCGNALdVLPnyFPPGSLQKI 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 339894634 121 TIGFglrnvPD-------------YLGALKEMHRVLKPGGMV 149
Cdd:pfam02390 77 FINF-----PDpwpkkrhhkrrllQPEFLKEYARVLKPGGVL 113
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
40-151 |
1.61e-04 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 41.67 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 40 HVMKEMRVKKNSVALDVCCGT---AdwtIALSKAVgPNGEVTGLDFSENMLKVGK---EKTSAMDNVHLVHGDAMHLPFE 113
Cdd:COG2890 103 LALALLPAGAPPRVLDLGTGSgaiA---LALAKER-PDARVTAVDISPDALAVARrnaERLGLEDRVRFLQGDLFEPLPG 178
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 339894634 114 DDSFD-------YVTIGF--GL-RNVPDY--LGAL--------------KEMHRVLKPGGMVVC 151
Cdd:COG2890 179 DGRFDlivsnppYIPEDEiaLLpPEVRDHepRLALdggedgldfyrriiAQAPRLLKPGGWLLL 242
|
|
| FtsJ |
pfam01728 |
FtsJ-like methyltransferase; This family consists of FtsJ from various bacterial and archaeal ... |
47-188 |
2.24e-04 |
|
FtsJ-like methyltransferase; This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesized that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.
Pssm-ID: 426399 Cd Length: 179 Bit Score: 40.65 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 47 VKKNSVALDVCCGTADWTIALSKAVgpNGEVTGLDfsenMLKVGKEKTSAMDNVHLVHGDAMHLPFEDDSFDYVTIGF-- 124
Cdd:pfam01728 19 LKPGKTVLDLGAAPGGWSQVALQRG--AGKVVGVD----LGPMQLWKPRNDPGVTFIQGDIRDPETLDLLEELLGRKVdl 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 125 ----------GLRNVPDYL------GALKEMHRVLKPGGMVVCLETSQPTMPVFKQVYKLYFRFVM----PIFGKlfaKS 184
Cdd:pfam01728 93 vlsdgspfisGNKVLDHLRsldlvkAALEVALELLRKGGNFVCKVFQGEDFSELLYLLKLGFEKVGvfkpPASRP---ES 169
|
....
gi 339894634 185 KEEY 188
Cdd:pfam01728 170 SEEY 173
|
|
| TrmB |
COG0220 |
tRNA G46 N7-methylase TrmB [Translation, ribosomal structure and biogenesis]; tRNA G46 ... |
49-151 |
3.36e-04 |
|
tRNA G46 N7-methylase TrmB [Translation, ribosomal structure and biogenesis]; tRNA G46 N7-methylase TrmB is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439990 Cd Length: 204 Bit Score: 40.51 E-value: 3.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 49 KNSVALDVCCGTADWTIALSKAvgpNGEVT--GLDFSENMLKVGKEKTSA--MDNVHLVHGDAMHLP--FEDDSFDYVTI 122
Cdd:COG0220 32 DAPLVLEIGFGKGEFLVELAAA---NPDINfiGIEVHEPGVAKALKKAEEegLTNVRLLRGDAVELLelFPDGSLDRIYL 108
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 339894634 123 GFglrnvPD-------------YLGALKEMHRVLKPGGMVVC 151
Cdd:COG0220 109 NF-----PDpwpkkrhhkrrlvQPEFLALLARVLKPGGELHL 145
|
|
| CobL |
COG2242 |
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ... |
44-154 |
3.94e-04 |
|
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 441843 [Multi-domain] Cd Length: 403 Bit Score: 40.92 E-value: 3.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 44 EMRVKKNSVALDVCCGTADWTIALSKAvGPNGEVTGLDFSE--------NMLKVGkektsaMDNVHLVHGDA----MHLP 111
Cdd:COG2242 242 KLALRPGDVLWDIGAGSGSVSIEAARL-APGGRVYAIERDPeraaliraNARRFG------VPNVEVVEGEApealADLP 314
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 339894634 112 feddSFDYVTIGFGLRNVPDYLGALKEmhrVLKPGGMVVC----LET 154
Cdd:COG2242 315 ----DPDAVFIGGSGGNLPEILEACWA---RLRPGGRLVAnavtLET 354
|
|
| Methyltransf_24 |
pfam13578 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
56-151 |
4.95e-04 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 433324 [Multi-domain] Cd Length: 106 Bit Score: 38.44 E-value: 4.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 56 VCCGTadWTIALSKAVGPNG--EVTGLDFSENMLKVGK--EKTSAMDNVHLVHGDAMHL--PFEDDSFDYVTIGfGLRNV 129
Cdd:pfam13578 5 TYSGV--STLWLAAALRDNGlgRLTAVDPDPGAEEAGAllRKAGLDDRVRLIVGDSREAlpSLADGPIDLLFID-GDHTY 81
|
90 100
....*....|....*....|..
gi 339894634 130 PDYLGALKEMHRVLKPGGMVVC 151
Cdd:pfam13578 82 EAVLNDLELWLPRLAPGGVILF 103
|
|
| rADc |
smart00650 |
Ribosomal RNA adenine dimethylases; |
37-130 |
6.19e-04 |
|
Ribosomal RNA adenine dimethylases;
Pssm-ID: 128898 Cd Length: 169 Bit Score: 39.42 E-value: 6.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 37 WRKHVMKEMRVKKNSVALDVCCGTADWTIALSKAVGPngeVTGLDFSENMLKVGKEKTSAMDNVHLVHGDAMHLPFEDDS 116
Cdd:smart00650 1 VIDKIVRAANLRPGDTVLEIGPGKGALTEELLERAKR---VTAIEIDPRLAPRLREKFAAADNLTVIHGDALKFDLPKLQ 77
|
90
....*....|....
gi 339894634 117 FDYVtigFGlrNVP 130
Cdd:smart00650 78 PYKV---VG--NLP 86
|
|
| PRK06922 |
PRK06922 |
class I SAM-dependent methyltransferase; |
73-150 |
1.89e-03 |
|
class I SAM-dependent methyltransferase;
Pssm-ID: 180751 [Multi-domain] Cd Length: 677 Bit Score: 39.08 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 73 PNGEVTGLDFSENMLK-VGKEKTSAMDNVHLVHGDAMHLP--FEDDSFD---YVTIGFGLRNVPDYLG----------AL 136
Cdd:PRK06922 441 EDKRIYGIDISENVIDtLKKKKQNEGRSWNVIKGDAINLSssFEKESVDtivYSSILHELFSYIEYEGkkfnhevikkGL 520
|
90
....*....|....
gi 339894634 137 KEMHRVLKPGGMVV 150
Cdd:PRK06922 521 QSAYEVLKPGGRII 534
|
|
| COG2521 |
COG2521 |
Predicted archaeal methyltransferase [General function prediction only]; |
46-147 |
5.03e-03 |
|
Predicted archaeal methyltransferase [General function prediction only];
Pssm-ID: 442011 [Multi-domain] Cd Length: 285 Bit Score: 37.19 E-value: 5.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 46 RVKKNSVALDVCCG---TAdwtIALSKAvgpnG--EVTGLDFSENMLKVGK----EKTSAMDNVHLVHGDAMHL--PFED 114
Cdd:COG2521 129 GVRRGDRVLDTCTGlgyTA---IEALKR----GarEVITVEKDPNVLELAElnpwSRELANERIKIILGDASEVikTFPD 201
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 339894634 115 DSFDYVtIG----FGLRnvpdylGAL------KEMHRVLKPGG 147
Cdd:COG2521 202 ESFDAI-IHdpprFSLA------GELyslefyRELYRVLKPGG 237
|
|
| COG4076 |
COG4076 |
Predicted RNA methylase [General function prediction only]; |
44-171 |
6.15e-03 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 443253 [Multi-domain] Cd Length: 230 Bit Score: 36.94 E-value: 6.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 44 EMRVKKNSVALDVCCGTAdwtiALSKAVGPNG--EVTGLDFSENMLKVGKEKTSA---MDNVHLVHGDAMHLPFEDDsFD 118
Cdd:COG4076 30 ERVVKPGDVVLDIGTGSG----LLSMLAARAGakKVYAVEVNPDIAAVARRIIAAnglSDRITVINADATDLDLPEK-AD 104
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 339894634 119 YV------TIGFGLRNVPDYLGAlkeMHRVLKPGGMVVCLETSQPTMPVFKQVYKLYFR 171
Cdd:COG4076 105 VIisemldTALLDEGQVPILNHA---RKRLLKPGGRIIPERITNAAQPVESPVDAEGFE 160
|
|
| Pcm |
COG2518 |
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ... |
45-159 |
7.00e-03 |
|
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442008 [Multi-domain] Cd Length: 197 Bit Score: 36.60 E-value: 7.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 45 MRVKKNSVALDVCCGTAdWTIA-LSKAVGpngEVTGLDFSENMLKVGKEKTSAM--DNVHLVHGDAMH-LPfEDDSFD-- 118
Cdd:COG2518 62 LDLKPGDRVLEIGTGSG-YQAAvLARLAG---RVYSVERDPELAERARERLAALgyDNVTVRVGDGALgWP-EHAPFDri 136
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 339894634 119 YVTigFGLRNVPDylgALKEMhrvLKPGGMVVCLETSQPTM 159
Cdd:COG2518 137 IVT--AAAPEVPE---ALLEQ---LAPGGRLVAPVGEGGVQ 169
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
46-121 |
8.04e-03 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 36.66 E-value: 8.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 46 RVKKNSVALDVCCGTAdwTIALskAV---GPNGEVTGLDFSENMLKVGKE--KTSAMDN-VHLVHGDAMHLP--FEDDSF 117
Cdd:COG4123 34 PVKKGGRVLDLGTGTG--VIAL--MLaqrSPGARITGVEIQPEAAELARRnvALNGLEDrITVIHGDLKEFAaeLPPGSF 109
|
....
gi 339894634 118 DYVT 121
Cdd:COG4123 110 DLVV 113
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
53-150 |
9.28e-03 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 35.94 E-value: 9.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 339894634 53 ALDVCCGtadW---TIALSKAvGPNGEVTGLDFSENMLKVGKE--KTSAMDNVHLVHGDAMHlPFEDDSFDYVtigfgLR 127
Cdd:COG2813 53 VLDLGCG---YgviGLALAKR-NPEARVTLVDVNARAVELARAnaAANGLENVEVLWSDGLS-GVPDGSFDLI-----LS 122
|
90 100 110
....*....|....*....|....*....|....*.
gi 339894634 128 NVP------DYLGALKEM----HRVLKPGG---MVV 150
Cdd:COG2813 123 NPPfhagraVDKEVAHALiadaARHLRPGGelwLVA 158
|
|
| |
