|
Name |
Accession |
Description |
Interval |
E-value |
| recA |
PRK09354 |
recombinase A; Provisional |
1-207 |
1.69e-171 |
|
recombinase A; Provisional
Pssm-ID: 236476 [Multi-domain] Cd Length: 349 Bit Score: 474.28 E-value: 1.69e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSQPDTGEQALEIADALV 80
Cdd:PRK09354 55 GGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 81 RSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGN 160
Cdd:PRK09354 135 RSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGN 214
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 262112892 161 ALKFYASVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIF 207
Cdd:PRK09354 215 ALKFYASVRLDIRRIGTIKDGDEVIGNRTKVKVVKNKVAPPFKQAEF 261
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
1-207 |
8.08e-167 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 462.72 E-value: 8.08e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSQPDTGEQALEIADALV 80
Cdd:COG0468 58 GGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGIAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLV 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 81 RSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGN 160
Cdd:COG0468 138 RSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGAISKSNTTVIFINQLREKIGVMFGNPETTTGGN 217
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 262112892 161 ALKFYASVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIF 207
Cdd:COG0468 218 ALKFYASVRLDIRRIGTIKDGDEVIGNRTRVKVVKNKVAPPFKEAEF 264
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
1-207 |
6.42e-152 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 421.42 E-value: 6.42e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSQPDTGEQALEIADALV 80
Cdd:pfam00154 47 GGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAFIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLV 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 81 RSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGN 160
Cdd:pfam00154 127 RSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSISKSNTTVIFINQIREKIGVMFGNPETTTGGR 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 262112892 161 ALKFYASVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIF 207
Cdd:pfam00154 207 ALKFYASVRLDIRRIGQIKQGEEVIGNKTKVKVVKNKVAPPFKEAEF 253
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
1-207 |
5.45e-151 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 418.11 E-value: 5.45e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSQPDTGEQALEIADALV 80
Cdd:cd00983 19 GGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIADTLI 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 81 RSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGN 160
Cdd:cd00983 99 RSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQLREKIGVMFGNPETTTGGN 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 262112892 161 ALKFYASVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIF 207
Cdd:cd00983 179 ALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPPFKQAEF 225
|
|
| tigrfam_recA |
TIGR02012 |
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ... |
1-207 |
1.38e-148 |
|
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 162659 [Multi-domain] Cd Length: 321 Bit Score: 415.23 E-value: 1.38e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSQPDTGEQALEIADALV 80
Cdd:TIGR02012 50 GGLPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAFIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLV 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 81 RSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGN 160
Cdd:TIGR02012 130 RSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGALSKSNTTAIFINQIREKIGVMFGNPETTTGGN 209
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 262112892 161 ALKFYASVRLDIRRIGSIKKNDEVIGNETRVKVVKNKVSPPFREAIF 207
Cdd:TIGR02012 210 ALKFYASVRLDIRRIGTVKQGEEVVGNRTKVKVVKNKVAPPFREAEF 256
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
1-197 |
4.88e-97 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 298.55 E-value: 4.88e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSQPDTGEQALEIADALV 80
Cdd:PRK09519 55 GGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLI 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 81 RSGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGN 160
Cdd:PRK09519 135 RSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGK 214
|
170 180 190
....*....|....*....|....*....|....*..
gi 262112892 161 ALKFYASVRLDIRRIGSIKKNDEVIGNETRVKVVKNK 197
Cdd:PRK09519 215 ALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNK 251
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
6-174 |
1.93e-53 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 169.07 E-value: 1.93e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 6 GRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYA-----------GKLGVNVADLLVSQPDTGEQALE 74
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLvqileaspsseLELAEALSRLLYFRPPDTLAHLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 75 IADALVRSGS----IDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMF 150
Cdd:cd01393 81 ALDSLPESLFpppnTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGGS 160
|
170 180
....*....|....*....|....*
gi 262112892 151 G-NPETTTGGNALKFYASVRLDIRR 174
Cdd:cd01393 161 GaSLVPPALGNTWEHSVSTRLLLYR 185
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
1-147 |
1.64e-17 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 77.35 E-value: 1.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEhALDI----QYAGKLGVNVAD-LLVSQP-DTGEQALE 74
Cdd:cd01394 14 GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTE-GLSPerfqQIAGERFESIASnIIVFEPySFDEQGVA 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 262112892 75 IADA--LVRSGSIDMIVIDSVAALVpKAEiegEMGDSlpGLQARLMSQaLRKLTGTIKRTNCLVIFINQIRMKIG 147
Cdd:cd01394 93 IQEAekLLKSDKVDLVVVDSATALY-RLE---LGDDS--EANRELSRQ-MSKLLSIARKYDIPVVITNQVYSDID 160
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
1-147 |
2.27e-12 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 63.20 E-value: 2.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEhALDI----QYAGKLGVNVAD-LLVSQP---DTGEQA 72
Cdd:TIGR02237 7 GGVERGTITQIYGPPGSGKTNICMILAVNAARQGKKVVYIDTE-GLSPerfkQIAEDRPERALSnFIVFEVfdfDEQGVA 85
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 262112892 73 LEIADALVRSGSIDMIVIDSVAALVpKAEIEGEMGDSLPGLQARlmsqaLRKLTGTIKRTNCLVIFINQIRMKIG 147
Cdd:TIGR02237 86 IQKTSKFIDRDSASLVVVDSFTALY-RLELSDDRISRNRELARQ-----LTLLLSLARKKNLAVVITNQVYTDVN 154
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
1-147 |
2.44e-12 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 63.34 E-value: 2.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEhALDI----QYAGKLGVNVAD-LLVSQP-DTGEQALE 74
Cdd:PRK09361 18 GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTE-GLSPerfkQIAGEDFEELLSnIIIFEPsSFEEQSEA 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 262112892 75 IADA--LVRSgSIDMIVIDSVAALVpKAEIEGEMGDSLpgLQARLMSQaLRKLTGTIKRTNCLVIFINQIRMKIG 147
Cdd:PRK09361 97 IRKAekLAKE-NVGLIVLDSATSLY-RLELEDEEDNSK--LNRELGRQ-LTHLLKLARKHDLAVVITNQVYSDID 166
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
1-177 |
2.72e-12 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 63.11 E-value: 2.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKT----TLTLQVIAEMQKLGGTAA--FIDAEHALDIQ-------------YAGKLGVN---- 57
Cdd:cd19493 6 GGLPLGAITEITGASGSGKTqfalTLASSAAMPARKGGLDGGvlYIDTESKFSAErlaeiaearfpeaFSGFMEENerae 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 58 -VAD-LLVSQPDTGEQALEIADAL---VRSGSIDMIVIDSVAALVPKaeiegEMGDSLPGLQARlmSQALRKLTGTIKRT 132
Cdd:cd19493 86 eMLKrVAVVRVTTLAQLLERLPNLeehILSSGVRLVVIDSIAALVRR-----EFGGSDGEVTER--HNALAREASSLKRL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 262112892 133 ----NCLVIFINQIRMKIGVMFGNPETTTG--GNALKFYASVRLDIRRIGS 177
Cdd:cd19493 159 aeefRIAVLVTNQATTHFGDAGDGSSGVTAalGDAWAHAVNTRLRLERCLL 209
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
1-154 |
6.36e-12 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 62.24 E-value: 6.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALD--IQYAGKLGVNVADLLVS-------------Q 65
Cdd:COG0467 15 GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEqlLRRAESLGLDLEEYIESgllriidlspeelG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 66 PDTGEQALEIADAlVRSGSIDMIVIDSVAALVpkaeiegemgDSLPGLQARLmsQALRKLTGTIKRTNCLVIFINQIRMK 145
Cdd:COG0467 95 LDLEELLARLREA-VEEFGAKRVVIDSLSGLL----------LALPDPERLR--EFLHRLLRYLKKRGVTTLLTSETGGL 161
|
....*....
gi 262112892 146 IGVMFGNPE 154
Cdd:COG0467 162 EDEATEGGL 170
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
5-175 |
2.65e-11 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 59.31 E-value: 2.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 5 RGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYAGKLGVNVADLLVSqpDTGEQALEIADALVRSGS 84
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 85 IDMIVIDSVAALVPKAEiegemgdslpgLQARLMSQALRKLTGTIKRTNCLVIFINqirmkigvmfgNPETTTGGNALKF 164
Cdd:smart00382 79 PDVLILDEITSLLDAEQ-----------EALLLLLEELRLLLLLKSEKNLTVILTT-----------NDEKDLGPALLRR 136
|
170
....*....|.
gi 262112892 165 YASVRLDIRRI 175
Cdd:smart00382 137 RFDRRIVLLLI 147
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
1-142 |
7.63e-11 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 59.61 E-value: 7.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQ------KLGGTAAFIDAEHALDIQ----------------YAGKLGVNV 58
Cdd:cd19491 7 GGIPVGGITEIAGESGAGKTQLCLQLALTVQlprelgGLGGGAVYICTESSFPSKrlqqlasslpkryhleKAKNFLDNI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 59 ADLLVSQPDTGEQAL-EIADALVRSGSIDMIVIDSVAALVpKAEIEGEMGDSLpgLQARLMSQALRKLTGTIKRTNCLVI 137
Cdd:cd19491 87 FVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALF-RSEFDTSRSDLV--ERAKYLRRLADHLKRLADKYNLAVV 163
|
....*
gi 262112892 138 FINQI 142
Cdd:cd19491 164 VVNQV 168
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
1-207 |
4.55e-10 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 57.97 E-value: 4.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQK------LGGTAAFIDAEHALD----IQYAGKLGVNVADLL----VSQP 66
Cdd:PRK04301 97 GGIETQSITEFYGEFGSGKTQICHQLAVNVQLpeekggLEGKAVYIDTEGTFRperiEQMAEALGLDPDEVLdnihVARA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 -DTGEQAL--EIADALVRSG-SIDMIVIDSVAALVpKAEIEGEmgDSLPGLQARLMSQ--ALRKLTGTIkrtNCLVIFIN 140
Cdd:PRK04301 177 yNSDHQMLlaEKAEELIKEGeNIKLVIVDSLTAHF-RAEYVGR--GNLAERQQKLNKHlhDLLRLADLY---NAAVVVTN 250
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 262112892 141 QIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRigsiKKNDEVIgnetrVKVVKnkvSP--PFREAIF 207
Cdd:PRK04301 251 QVMARPDAFFGDPTQPIGGHILGHTATFRIYLRK----SKGNKRI-----ARLVD---SPhlPEGEAVF 307
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
1-207 |
6.25e-10 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 56.93 E-value: 6.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL--TLQVIA----EMQKLGGTAAFIDAEHALD----IQYAGKLGVNVADLLVSQP---- 66
Cdd:pfam08423 32 GGIETGSITEIFGEFRTGKTQLchTLCVTCqlplEMGGGEGKALYIDTEGTFRperlVAIAERYGLDPEDVLDNVAyara 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 ---DTGEQALEIADALVRSGSIDMIVIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTGTIKRTNCLVIFINQ 141
Cdd:pfam08423 112 ynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSGR-GE----LAERQQhlAKFLRTLQRLADEFGVAVVITNQ 185
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 262112892 142 IRMKIG---VMF-GNPETTTGGNALKFYASVRLDIRrigsiKKNDevignETRV-KVVKnkvSP--PFREAIF 207
Cdd:pfam08423 186 VVAQVDgaaGMFsGDPKKPIGGHIMAHASTTRLSLR-----KGRG-----EQRIcKIYD---SPclPESEAVF 245
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
1-207 |
2.48e-09 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 55.06 E-value: 2.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQK------LGGTAAFIDAEHALD----IQYAGKLGVNVADLL----VSQP 66
Cdd:cd19515 14 GGIETQAITEVFGEFGSGKTQLCHQLAVNVQLppeeggLNGKAVYIDTENTFRperiMQMAKALGLDPDEVLdniyVARA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 -DTGEQAL---EIADALVRSGSIDMIVIDSVAALVpKAEIEGEmgDSLPGLQARLmSQALRKLTGTIKRTNCLVIFINQI 142
Cdd:cd19515 94 yNSNHQMLlveKAEDLIKEGNNIKLLIVDSLTSHF-RAEYVGR--GTLAERQQKL-NKHLHDLHRLADLYNIAVLVTNQV 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 262112892 143 RMKIGVMFGNPETTTGGNALKFYASVRLDIRRigsiKKNDEVIgnetrVKVVKnkvSP--PFREAIF 207
Cdd:cd19515 170 MAKPDAFFGDPTQAIGGHILGHAATFRVYLRK----GKGGKRI-----ARLVD---SPhlPEGEAVF 224
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
3-139 |
7.92e-09 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 54.14 E-value: 7.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 3 LPRGRVVEIYGPESSGKTTLTLQVIAEMQK----LG-----GTAAFIDAE-HALDIQ-----YAGKLGVNVADL------ 61
Cdd:COG3598 10 LPEGGVTLLAGPPGTGKSFLALQLAAAVAAggpwLGrrvppGKVLYLAAEdDRGELRrrlkaLGADLGLPFADLdgrlrl 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 62 --LVSQPDTGEQALEIADALVRSGsIDMIVIDSVAALVPKAEIEGEmgdslpglQARLMSQALRKLtgtIKRTNCLVIFI 139
Cdd:COG3598 90 lsLAGDLDDTDDLEALERAIEEEG-PDLVVIDPLARVFGGDENDAE--------EMRAFLNPLDRL---AERTGAAVLLV 157
|
|
| COG4544 |
COG4544 |
Uncharacterized conserved protein [Function unknown]; |
1-91 |
9.89e-09 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 443609 [Multi-domain] Cd Length: 230 Bit Score: 53.39 E-value: 9.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPE-SSGKTTLTLQVIAEMQKLGGTAAFIDAEHALdiqYA---GKLGVNVADLLVSQPDTGEQALEIA 76
Cdd:COG4544 43 GGLPRGALHEILGPApGIGELGLLLPLLARLAQAGGPVLWIAPPYDL---YApglAAAGLDPERLLLVRARRPADALWAA 119
|
90
....*....|....*
gi 262112892 77 DALVRSGSIDMIVID 91
Cdd:COG4544 120 EEALRSGACGAVVAW 134
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
1-177 |
1.52e-08 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 53.02 E-value: 1.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAE-MQKLGGTAAFIDA-EHALDI-QYAGKLGVNVADL----------LVSQP- 66
Cdd:pfam06745 14 GGFPEGRVVLITGGPGTGKTIFGLQFLYNgALKYGEPGVFVTLeEPPEDLrENARSFGWDLEKLeeegklaiidASTSGi 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 ---------DTGEQALEIADAlVRSGSIDMIVIDSVAALvpkAEIEGEMgdslpglQARlmsQALRKLTGTIKRTNCLVI 137
Cdd:pfam06745 94 giaevedrfDLEELIERLREA-IREIGAKRVVIDSITTL---FYLLKPA-------VAR---EILRRLKRVLKGLGVTAI 159
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 262112892 138 FINQIRMKigvmfgnpETTTGGNALKFYAS---VRLDIRRIGS 177
Cdd:pfam06745 160 FTSEKPSG--------EGGIGGYGVEEFIVdgvIRLDLKEIEE 194
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
6-147 |
3.73e-08 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 51.07 E-value: 3.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 6 GRVVEIYGPESSGKTTLTLQVIAEMQ------KLGGTAAFIDAEHALDIQYagklgvnvadllVSQPDTGEQALEIA--D 77
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQipkcfgGLAGEAIYIDTEGSFNIHY------------FRVHDYVELLALINslP 68
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 262112892 78 ALVRSGS-IDMIVIDSVAALVpKAEIEGemgdslPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIG 147
Cdd:cd19492 69 KFLEDHPkVKLIVVDSIAFPF-RHDFDD------LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKIS 132
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
1-174 |
5.22e-08 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 52.04 E-value: 5.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL--TLQVIAEM--QKLGGT--AAFIDAEHALD----IQYAGKLGVNVADLL----VSQP 66
Cdd:PLN03186 118 GGIETGSITEIYGEFRTGKTQLchTLCVTCQLplDQGGGEgkAMYIDTEGTFRpqrlIQIAERFGLNGADVLenvaYARA 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 DTGEQALEIadaLVRSGSI------DMIVIDSVAALVpKAEIEGEmGDslpgLQAR--LMSQALRKLTGTIKRTNCLVIF 138
Cdd:PLN03186 198 YNTDHQSEL---LLEAASMmaetrfALMIVDSATALY-RTEFSGR-GE----LSARqmHLGKFLRSLQRLADEFGVAVVI 268
|
170 180 190
....*....|....*....|....*....|....*....
gi 262112892 139 INQIRMKI--GVMFGNPETT-TGGNALKFYASVRLDIRR 174
Cdd:PLN03186 269 TNQVVAQVdgSAFFAGPQLKpIGGNIMAHASTTRLALRK 307
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
6-147 |
5.26e-08 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 51.19 E-value: 5.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 6 GRVVEIYGPESSGKTTLTLQVIA-----------EMQKLGGTAAFIDAEHALDI----QYAGKLGVNVADLLVSQPDTGE 70
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAArcilpsswggvPLGGLEAAVVFIDTDGRFDIlrlrSILEARIRAAIQAANSSDDEED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 71 QALEIADALVR----------------------------SGSIDMIVIDSVAALVPKAEIEGEMGDSLPGLQARLM---S 119
Cdd:cd19490 81 VEEIARECLQRlhifrchsslqllatllslenyllslsaNPELGLLLIDSISAFYWQDRFSAELARAAPLLQEAALraiL 160
|
170 180
....*....|....*....|....*...
gi 262112892 120 QALRKLTgtiKRTNCLVIFINQIRMKIG 147
Cdd:cd19490 161 RELRRLR---RRFQLVVIATKQALFPGK 185
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
1-143 |
7.43e-08 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 50.73 E-value: 7.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALD--IQYAGKLGVNVADL-------LVSQPDTGEQ 71
Cdd:cd01124 14 GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLFFTFEESPErlLRNAKSFGWDFDEMedegkliIVDAPPTEAG 93
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 262112892 72 ALEIAD------ALVRSGSIDMIVIDSVAALvpkaeiegemgdSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIR 143
Cdd:cd01124 94 RFSLDEllsrilSIIKSFKAKRVVIDSLSGL------------RRAKEDQMRARRIVIALLNELRAAGVTTIFTSEMR 159
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
1-174 |
7.78e-07 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 48.62 E-value: 7.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL------TLQVIAEMQKLGGTAAFIDAEHALD----IQYAGKLGVN----VADLLVSQP 66
Cdd:PLN03187 121 GGIETRCITEAFGEFRSGKTQLahtlcvTTQLPTEMGGGNGKVAYIDTEGTFRpdriVPIAERFGMDadavLDNIIYARA 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 DTGEQ---ALEIADALVRSGSIDMIVIDSVAALVPKAEI-EGEMGDSlpglQARLmSQALRKLTGTIKRTNCLVIFINQI 142
Cdd:PLN03187 201 YTYEHqynLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTgRGELAER----QQKL-AQMLSRLTKIAEEFNVAVYMTNQV 275
|
170 180 190
....*....|....*....|....*....|....
gi 262112892 143 RMKIG--VMFGNPETTTGGNALKFYASVRLDIRR 174
Cdd:PLN03187 276 IADPGggMFISDPKKPAGGHVLAHAATIRLMLRK 309
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
1-174 |
7.94e-07 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 47.91 E-value: 7.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL------TLQVIAEMQKLGGTAAFIDAEHALD----IQYAGKLGVNVADLL-------V 63
Cdd:cd01123 14 GGIETGSITEMFGEFRTGKTQLchtlavTCQLPIDRGGGEGKAIYIDTEGTFRperlRAIAQRFGLDPDDVLdnvayarA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 64 SQPDTGEQALEIADALVRSGSIDMIVIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTGTIKRTNCLVIFINQ 141
Cdd:cd01123 94 FNSDHQTQLLDQAAAMMVESRFKLLIVDSATALY-RTDYSGR-GE----LSARQMhlAKFLRMLQRLADEFGVAVVVTNQ 167
|
170 180 190
....*....|....*....|....*....|....*.
gi 262112892 142 IRMKIG---VMFGNPETTTGGNALKFYASVRLDIRR 174
Cdd:cd01123 168 VVAQVDgamMFAADPKKPIGGNILAHASTTRLYLRK 203
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
1-207 |
2.40e-06 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 46.54 E-value: 2.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL------TLQVIAEMQKLGGTAAFIDAEHALD----IQYAGKLGVNVADLL--VS---- 64
Cdd:cd19513 14 GGIETGSITELFGEFRTGKTQLchtlavTCQLPIDQGGGEGKALYIDTEGTFRperlLAIAERYGLNGEDVLdnVAyara 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 65 -QPDTGEQALEIADALVRSGSIDMIVIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTGTIKRTNCLVIFINQ 141
Cdd:cd19513 94 yNTDHQMQLLIQASAMMAESRYALLIVDSATALY-RTDYSGR-GE----LSARQMhlAKFLRMLQRLADEFGVAVVITNQ 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 142 IRMKI--GVMF-GNPETTTGGNALKFYASVRLDIRRigsikkndeviGN-ETRVKVVKNKVSPPFREAIF 207
Cdd:cd19513 168 VVAQVdgAAMFaGDPKKPIGGNIMAHASTTRLYLRK-----------GRgETRICKIYDSPCLPEAEAVF 226
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
9-163 |
4.60e-06 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 44.03 E-value: 4.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 9 VEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAehaLDIqyagklgvnvadllvsqpdtgeqALEIADALVRSGSIDMI 88
Cdd:cd01120 1 ILITGPPGSGKTTLLLQFAEQALLSDEPVIFISF---LDT-----------------------ILEAIEDLIEEKKLDII 54
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 262112892 89 VIDSVAALVPKaeiegemgdsLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGNPETTTGGNALK 163
Cdd:cd01120 55 IIDSLSSLARA----------SQGDRSSELLEDLAKLLRAARNTGITVIATIHSDKFDIDRGGSSNDERLLKSLR 119
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
1-97 |
3.08e-05 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 43.01 E-value: 3.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEM-QKLGGTAAFID------AEHALDI-QYAGKLGVNVADLL-------VSQ 65
Cdd:cd19489 2 GGLRTGEITELVGESSSGKTQLCLTAAANVaSRSGQNVLYIDtkssfsARRLAQIlKSRAQDAEEIDKALqrirvvrVFD 81
|
90 100 110
....*....|....*....|....*....|....*...
gi 262112892 66 PDTGEQALEIADALVR------SGSIDMIVIDSVAALV 97
Cdd:cd19489 82 PYELLDLLEELRNTLSqqqenlYSRLKLVIIDSLSALI 119
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
1-174 |
3.09e-05 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 43.50 E-value: 3.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL--TLQVIAEMQKL----GGTAAFIDAEHALD----IQYAGKLGVN----VADLLVSQP 66
Cdd:cd19514 14 GGIESMSITEVFGEFRTGKTQLshTLCVTAQLPGSmgggGGKVAYIDTEGTFRpdriRPIAERFGVDhdavLDNILYARA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 DTGEQALEIADAL----VRSGSIDMIVIDSVAALVpKAEI--EGEMGDSlpglQARLmSQALRKLTGTIKRTNCLVIFIN 140
Cdd:cd19514 94 YTSEHQMELLDYVaakfHEEAVFRLLIIDSIMALF-RVDFsgRGELAER----QQKL-AQMLSRLQKISEEYNVAVFITN 167
|
170 180 190
....*....|....*....|....*....|....*..
gi 262112892 141 QIRMKIG--VMF-GNPETTTGGNALKFYASVRLDIRR 174
Cdd:cd19514 168 QVTADPGaaMTFqADPKKPIGGHILAHASTTRISLRK 204
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
1-139 |
3.38e-05 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 43.29 E-value: 3.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDiQY---AGKLGVNVADLLVsqpdTGEQALEIAD 77
Cdd:cd01121 77 GGLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYVSGEESLS-QIklrAERLGLGSDNLYL----LAETNLEAIL 151
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 262112892 78 ALVRSGSIDMIVIDSVAALVPKAEiegemgDSLPG--LQARLMSQALRKLTgtiKRTNCLVIFI 139
Cdd:cd01121 152 AEIEELKPSLVVIDSIQTVYSPEL------TSSPGsvSQVRECAAELLRLA---KETGIPVFLV 206
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
1-207 |
4.86e-05 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 43.17 E-value: 4.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL------TLQVIAEMQKLGGTAAFIDAEHALD----IQYAGKLGVNVADLL--VS---- 64
Cdd:TIGR02239 91 GGIETGSITEIFGEFRTGKTQLchtlavTCQLPIDQGGGEGKALYIDTEGTFRperlLAIAERYGLNPEDVLdnVAyara 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 65 -QPDTGEQALEIADALVRSGSIDMIVIDSVAALVpKAEIEGEmGDslpgLQARLMSQA--LRKLTGTIKRTNCLVIFINQ 141
Cdd:TIGR02239 171 yNTDHQLQLLQQAAAMMSESRFALLIVDSATALY-RTDFSGR-GE----LSARQMHLArfLRSLQRLADEFGVAVVITNQ 244
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 142 IRMKI---GVMF-GNPETTTGGNALKFYASVRLDIRRiGSikkndevigNETRVKVVKNKVSPPFREAIF 207
Cdd:TIGR02239 245 VVAQVdgaGSMFaGDPKKPIGGNIMAHASTTRLSLRK-GR---------GEQRICKIYDSPCLPESEAMF 304
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
3-139 |
1.39e-04 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 41.21 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 3 LPRGRVVEIYGPESSGKTTLTLQVIAEM-----------QKLGGTAAFIDAE----------HALDIQYAGKLGVNVADL 61
Cdd:pfam13481 30 LPAGGLGLLAGAPGTGKTTLALDLAAAVatgkpwlggprVPEQGKVLYVSAEgpadelrrrlRAAGADLDLPARLLFLSL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 62 LVSQP----DTGEQAL-----EIADALVRSGSIDMIVIDSVAALVPkaeiegemGDSLPGLQARLMSQALRKLtgtIKRT 132
Cdd:pfam13481 110 VESLPlfflDRGGPLLdadvdALEAALEEVEDPDLVVIDPLARALG--------GDENSNSDVGRLVKALDRL---ARRT 178
|
....*..
gi 262112892 133 NCLVIFI 139
Cdd:pfam13481 179 GATVLLV 185
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
1-174 |
1.55e-04 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 41.69 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL--TLQVIA----EMQKLGGTAAFIDAEHALD----IQYAGKLGVN----VADLLVSQP 66
Cdd:TIGR02238 91 GGIESMSITEVFGEFRCGKTQLshTLCVTAqlprEMGGGNGKVAYIDTEGTFRpdriRAIAERFGVDpdavLDNILYARA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 DTGEQALEIAD---ALVRSGSIDMIVIDSVAALVpKAEIEGEmgDSLPGLQARLmSQALRKLTGTIKRTNCLVIFINQIR 143
Cdd:TIGR02238 171 YTSEHQMELLDylaAKFSEEPFRLLIVDSIMALF-RVDFSGR--GELSERQQKL-AQMLSRLNKISEEFNVAVFVTNQVQ 246
|
170 180 190
....*....|....*....|....*....|....
gi 262112892 144 MKIG--VMF-GNPETTTGGNALKFYASVRLDIRR 174
Cdd:TIGR02238 247 ADPGatMTFiADPKKPIGGHVLAHASTTRILLRK 280
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
1-174 |
8.78e-04 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 39.21 E-value: 8.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTL------TLQVIAEMQKLGGTAAFIDAEHALD----IQYAGKLGVNVADLL----VSQP 66
Cdd:PTZ00035 113 GGIETGSITELFGEFRTGKTQLchtlcvTCQLPIEQGGGEGKVLYIDTEGTFRperiVQIAERFGLDPEDVLdniaYARA 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 67 DTGEQALEI---ADALVRSGSIDMIVIDSVAALVpKAEIEGEmGDslpgLQARLM--SQALRKLTGTIKRTNCLVIFINQ 141
Cdd:PTZ00035 193 YNHEHQMQLlsqAAAKMAEERFALLIVDSATALF-RVDYSGR-GE----LAERQQhlGKFLRALQKLADEFNVAVVITNQ 266
|
170 180 190
....*....|....*....|....*....|....*.
gi 262112892 142 IRMKIG---VMFGNPETTTGGNALKFYASVRLDIRR 174
Cdd:PTZ00035 267 VMADVDgasMFVADPKKPIGGHIIAHASTTRLSLRK 302
|
|
| KaiC-like_N |
cd19488 |
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
1-40 |
1.12e-03 |
|
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410896 [Multi-domain] Cd Length: 225 Bit Score: 38.48 E-value: 1.12e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 262112892 1 GGLPRGRVVEIYGPESSGKTTLTLQVIAEMQKLGGTAAFI 40
Cdd:cd19488 14 GGLPPRRLYLVEGAPGTGKTTLALQFLLEGAANGETGLYI 53
|
|
| AAA_24 |
pfam13479 |
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins. |
5-139 |
1.58e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
Pssm-ID: 433243 Cd Length: 199 Bit Score: 38.08 E-value: 1.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 262112892 5 RGRVVEIYGPESSGKTTLTLQViaemqklgGTAAFIDAEHALDIQYAGKLgvNVADLLVSQPDTGEQALEIADALVRsgS 84
Cdd:pfam13479 1 KKLKILIYGPSGIGKTTFAKTL--------PKPLFLDTEKGSKALDGDRF--PDIVIRDSWQDFLDAIDELTAAELA--D 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 262112892 85 IDMIVIDSVAALV-----------PKAEIEGEMGDSLP-GLQARLMSQALRKLTGTIKRtnclVIFI 139
Cdd:pfam13479 69 YKTIVIDTVDWLErlclayickqnGKGSSIEDGGYGKGyGELGEEFRRLLDALQELGKN----VIFT 131
|
|
| ATPase_2 |
pfam01637 |
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is ... |
11-51 |
3.41e-03 |
|
ATPase domain predominantly from Archaea; This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.
Pssm-ID: 376582 [Multi-domain] Cd Length: 222 Bit Score: 37.30 E-value: 3.41e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 262112892 11 IYGPESSGKTTLTLQVIAEMQKLGGTAAFIDAEHALDIQYA 51
Cdd:pfam01637 25 IYGPEGCGKTALLRESIENLLDLGYYVIYYDPLRRYFISKL 65
|
|
| NadR3 |
COG3172 |
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase ... |
7-25 |
7.47e-03 |
|
Nicotinamide riboside kinase [Coenzyme transport and metabolism]; Nicotinamide riboside kinase is part of the Pathway/BioSystem: NAD biosynthesis
Pssm-ID: 442405 [Multi-domain] Cd Length: 178 Bit Score: 35.95 E-value: 7.47e-03
|
| |
