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Conserved domains on  [gi|238933750|emb|CAR21933|]
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KLTH0C03344p [Lachancea thermotolerans CBS 6340]

Protein Classification

LamG domain-containing protein( domain architecture ID 10161224)

LamG (Laminin G) domain-containing protein may serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules; similar to Oncorhynchus mykiss sex hormone-binding globulin beta form that may participate in the local control of ovarian functions in salmonids

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LamG super family cl22861
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 95-306 6.01e-87

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


The actual alignment was detected with superfamily member cd02183:

Pssm-ID: 473984 [Multi-domain]  Cd Length: 203  Bit Score: 264.41  E-value: 6.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  95 YTYLGDAEKHDWIYEGYTMDYDkEDALVLAMPKNSGGTVLSSTRYVWYGKVGARLKTSHDAGVVTAFIMFSSVQDEIDYE 174
Cdd:cd02183    1 FDFTGNASSYDWTVTSGTVDYD-DDGASLTIPKRGDGPTISSTFYIFYGKVEVTMKAAPGQGIVSSFVLQSDDLDEIDWE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 175 YVGNNLTQVQTNYYFEGV-QNWTHSTNVST-TDTFDNYHLYEVDWHEDHIDWLIDGEVSRTLLKNStfnaTSGEYMFPQT 252
Cdd:cd02183   80 WVGGDLTQVQTNYFGKGNtTTYDRGGYHPVpNPQTEEFHTYTIDWTKDRITWYIDGKVVRTLTKAD----TTGGYGYPQT 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 238933750 253 PARIQISIWPGGNATNPVGTRSWAGGEINWdssdiqDYGYYYALLQGVNVTCYD 306
Cdd:cd02183  156 PMRLQIGIWAGGDPSNAPGTIEWAGGETDY------DKGPFTMYVKSVTVTDYS 203
ChtBD1_GH16 cd06923
Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl ...
 28-75 1.15e-26

Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl hydrolases; This subfamily includes Saccharomyces cerevisiae Utr2p, also known as Crh2p, which participates in the cross-linking of chitin to beta(1-3)- and beta(1-6) glucan in the cell wall, and S. cerevisiae Crr1p, a putative transglycosidase which is needed for proper spore wall assembly. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.


:

Pssm-ID: 211314  Cd Length: 47  Bit Score: 101.29  E-value: 1.15e-26
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 238933750  28 VYCNETlAACPEDKPCCSQYGVCGSGSYCLGGCNPRYSHNITACMPMP 75
Cdd:cd06923    1 ITCNET-SQCPEEWPCCSQYGECGTGPYCLGGCNPRYSFSLDSCMPMP 47
 
Name Accession Description Interval E-value
GH16_fungal_CRH1_transglycosylase cd02183
glycosylphosphatidylinositol-glucanosyltransferase; Group of fungal GH16 members related to ...
 95-306 6.01e-87

glycosylphosphatidylinositol-glucanosyltransferase; Group of fungal GH16 members related to Saccharomyces cerevisiae Crh1p. Chr1p and Crh2p are transglycosylases that are required for the linkage of chitin to beta(1-3)glucose branches of beta(1-6)glucan, an important step in the assembly of new cell wall. Both have been shown to be glycosylphosphatidylinositol (GPI)-anchored. A third homologous protein, Crr1p, functions in the formation of the spore wall. They belongs to the family 16 of glycosyl hydrolases that includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.


Pssm-ID: 185692 [Multi-domain]  Cd Length: 203  Bit Score: 264.41  E-value: 6.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  95 YTYLGDAEKHDWIYEGYTMDYDkEDALVLAMPKNSGGTVLSSTRYVWYGKVGARLKTSHDAGVVTAFIMFSSVQDEIDYE 174
Cdd:cd02183    1 FDFTGNASSYDWTVTSGTVDYD-DDGASLTIPKRGDGPTISSTFYIFYGKVEVTMKAAPGQGIVSSFVLQSDDLDEIDWE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 175 YVGNNLTQVQTNYYFEGV-QNWTHSTNVST-TDTFDNYHLYEVDWHEDHIDWLIDGEVSRTLLKNStfnaTSGEYMFPQT 252
Cdd:cd02183   80 WVGGDLTQVQTNYFGKGNtTTYDRGGYHPVpNPQTEEFHTYTIDWTKDRITWYIDGKVVRTLTKAD----TTGGYGYPQT 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 238933750 253 PARIQISIWPGGNATNPVGTRSWAGGEINWdssdiqDYGYYYALLQGVNVTCYD 306
Cdd:cd02183  156 PMRLQIGIWAGGDPSNAPGTIEWAGGETDY------DKGPFTMYVKSVTVTDYS 203
Glyco_hydro_16 pfam00722
Glycosyl hydrolases family 16;
108-282 1.78e-53

Glycosyl hydrolases family 16;


Pssm-ID: 395585 [Multi-domain]  Cd Length: 168  Bit Score: 177.01  E-value: 1.78e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  108 YEGYTMDYDKeDALVLAMPKNSGGTvLSSTRYVWYGKVGARLKTSHDAGVVTAFIMFS---SVQDEIDYEYVGNNLTQVQ 184
Cdd:pfam00722   1 WGGDNVSVSN-GGLTLTLDKYTGSG-FQSKFYYLYGKVEARIKAARGAGVVTAFYLSSedwDDHDEIDFEFLGNDTGQVQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  185 TNYYFEGVQNWTHSTNVSTTDTFDNYHLYEVDWHEDHIDWLIDGEVSRTLLKNSTfnatsGEYMFPQTPARIQISIWPGG 264
Cdd:pfam00722  79 TNVYGNGKGNRGEQRFSLWFDPTADFHTYSILWNPDKITWYVDGVPVRTLKNNDA-----GGVPYPQTPMRLYVSLWPGG 153

                         170
                  ....*....|....*...
gi 238933750  265 NATNPVGtrswaGGEINW 282
Cdd:pfam00722 154 DWATPGG-----GVKIDW 166
ChtBD1_GH16 cd06923
Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl ...
 28-75 1.15e-26

Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl hydrolases; This subfamily includes Saccharomyces cerevisiae Utr2p, also known as Crh2p, which participates in the cross-linking of chitin to beta(1-3)- and beta(1-6) glucan in the cell wall, and S. cerevisiae Crr1p, a putative transglycosidase which is needed for proper spore wall assembly. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.


Pssm-ID: 211314  Cd Length: 47  Bit Score: 101.29  E-value: 1.15e-26
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 238933750  28 VYCNETlAACPEDKPCCSQYGVCGSGSYCLGGCNPRYSHNITACMPMP 75
Cdd:cd06923    1 ITCNET-SQCPEEWPCCSQYGECGTGPYCLGGCNPRYSFSLDSCMPMP 47
BglS COG2273
Beta-glucanase, GH16 family [Carbohydrate transport and metabolism];
142-265 1.04e-16

Beta-glucanase, GH16 family [Carbohydrate transport and metabolism];


Pssm-ID: 441874 [Multi-domain]  Cd Length: 259  Bit Score: 79.65  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 142 YGKVGARLKTSHDAGVVTAFIMFSS-------VQDEID-YEYVGNNLTQVQTNYYFE---GVQNWTHSTNVSTTDTfDNY 210
Cdd:COG2273  107 YGRFEARAKLPKGQGLWPAFWMLGGdidggwpASGEIDiMEFVGKDPNKVHGNVHYGgynGGEGIGASYDLPFDAS-DDF 185

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 238933750 211 HLYEVDWHEDHIDWLIDGEVSRTLlknsTFNATSGEYMFpQTPARIQISIWPGGN 265
Cdd:COG2273  186 HTYAVEWTPDSIRWYVDGVLVHTV----TPADVGGPWPF-DQPFYLILNLAVGGN 235
PLN03161 PLN03161
Probable xyloglucan endotransglucosylase/hydrolase protein; Provisional
 119-228 1.42e-05

Probable xyloglucan endotransglucosylase/hydrolase protein; Provisional


Pssm-ID: 178706 [Multi-domain]  Cd Length: 291  Bit Score: 46.82  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 119 DALVLAMPKNSGGTVLSSTRYVwYGKVGARLK--TSHDAGVVTAFIMFS--SVQDEIDYEYVGNNLTQ---VQTNYYFEG 191
Cdd:PLN03161  47 DNLQLVLDQSSGSGIKSKRAFL-FGSIEMLIKlvPGNSAGTVTAYYLSStgSRHDEIDFEFLGNVSGQpytIHTNIYTQG 125

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 238933750 192 VQN-------WTHSTNvsttdtfdNYHLYEVDWHEDHIDWLIDG 228
Cdd:PLN03161 126 NGSreqqfrpWFDPTA--------DFHNYTIHWNPSEVVWYVDG 161
ChtBD1 smart00270
Chitin binding domain;
37-61 3.45e-03

Chitin binding domain;


Pssm-ID: 214593  Cd Length: 38  Bit Score: 35.03  E-value: 3.45e-03
                           10        20
                   ....*....|....*....|....*.
gi 238933750    37 CPeDKPCCSQYGVCGSGS-YCLGGCN 61
Cdd:smart00270  11 CP-NNLCCSQFGYCGSGDeYCGRGCQ 35
 
Name Accession Description Interval E-value
GH16_fungal_CRH1_transglycosylase cd02183
glycosylphosphatidylinositol-glucanosyltransferase; Group of fungal GH16 members related to ...
 95-306 6.01e-87

glycosylphosphatidylinositol-glucanosyltransferase; Group of fungal GH16 members related to Saccharomyces cerevisiae Crh1p. Chr1p and Crh2p are transglycosylases that are required for the linkage of chitin to beta(1-3)glucose branches of beta(1-6)glucan, an important step in the assembly of new cell wall. Both have been shown to be glycosylphosphatidylinositol (GPI)-anchored. A third homologous protein, Crr1p, functions in the formation of the spore wall. They belongs to the family 16 of glycosyl hydrolases that includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.


Pssm-ID: 185692 [Multi-domain]  Cd Length: 203  Bit Score: 264.41  E-value: 6.01e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  95 YTYLGDAEKHDWIYEGYTMDYDkEDALVLAMPKNSGGTVLSSTRYVWYGKVGARLKTSHDAGVVTAFIMFSSVQDEIDYE 174
Cdd:cd02183    1 FDFTGNASSYDWTVTSGTVDYD-DDGASLTIPKRGDGPTISSTFYIFYGKVEVTMKAAPGQGIVSSFVLQSDDLDEIDWE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 175 YVGNNLTQVQTNYYFEGV-QNWTHSTNVST-TDTFDNYHLYEVDWHEDHIDWLIDGEVSRTLLKNStfnaTSGEYMFPQT 252
Cdd:cd02183   80 WVGGDLTQVQTNYFGKGNtTTYDRGGYHPVpNPQTEEFHTYTIDWTKDRITWYIDGKVVRTLTKAD----TTGGYGYPQT 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 238933750 253 PARIQISIWPGGNATNPVGTRSWAGGEINWdssdiqDYGYYYALLQGVNVTCYD 306
Cdd:cd02183  156 PMRLQIGIWAGGDPSNAPGTIEWAGGETDY------DKGPFTMYVKSVTVTDYS 203
Glyco_hydro_16 pfam00722
Glycosyl hydrolases family 16;
108-282 1.78e-53

Glycosyl hydrolases family 16;


Pssm-ID: 395585 [Multi-domain]  Cd Length: 168  Bit Score: 177.01  E-value: 1.78e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  108 YEGYTMDYDKeDALVLAMPKNSGGTvLSSTRYVWYGKVGARLKTSHDAGVVTAFIMFS---SVQDEIDYEYVGNNLTQVQ 184
Cdd:pfam00722   1 WGGDNVSVSN-GGLTLTLDKYTGSG-FQSKFYYLYGKVEARIKAARGAGVVTAFYLSSedwDDHDEIDFEFLGNDTGQVQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  185 TNYYFEGVQNWTHSTNVSTTDTFDNYHLYEVDWHEDHIDWLIDGEVSRTLLKNSTfnatsGEYMFPQTPARIQISIWPGG 264
Cdd:pfam00722  79 TNVYGNGKGNRGEQRFSLWFDPTADFHTYSILWNPDKITWYVDGVPVRTLKNNDA-----GGVPYPQTPMRLYVSLWPGG 153

                         170
                  ....*....|....*...
gi 238933750  265 NATNPVGtrswaGGEINW 282
Cdd:pfam00722 154 DWATPGG-----GVKIDW 166
ChtBD1_GH16 cd06923
Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl ...
 28-75 1.15e-26

Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl hydrolases; This subfamily includes Saccharomyces cerevisiae Utr2p, also known as Crh2p, which participates in the cross-linking of chitin to beta(1-3)- and beta(1-6) glucan in the cell wall, and S. cerevisiae Crr1p, a putative transglycosidase which is needed for proper spore wall assembly. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.


Pssm-ID: 211314  Cd Length: 47  Bit Score: 101.29  E-value: 1.15e-26
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 238933750  28 VYCNETlAACPEDKPCCSQYGVCGSGSYCLGGCNPRYSHNITACMPMP 75
Cdd:cd06923    1 ITCNET-SQCPEEWPCCSQYGECGTGPYCLGGCNPRYSFSLDSCMPMP 47
GH16_lichenase cd02175
lichenase, member of glycosyl hydrolase family 16; Lichenase, also known as 1,3-1, ...
 142-277 5.70e-20

lichenase, member of glycosyl hydrolase family 16; Lichenase, also known as 1,3-1,4-beta-glucanase, is a member of glycosyl hydrolase family 16, that specifically cleaves 1,4-beta-D-glucosidic bonds in mixed-linked beta glucans that also contain 1,3-beta-D-glucosidic linkages. Natural substrates of beta-glucanase are beta-glucans from grain endosperm cell walls or lichenan from the Islandic moss, Cetraria islandica. This protein is found not only in bacteria but also in anaerobic fungi. This domain includes two seven-stranded antiparallel beta-sheets that are adjacent to one another forming a compact, jellyroll beta-sandwich structure.


Pssm-ID: 185684 [Multi-domain]  Cd Length: 212  Bit Score: 88.10  E-value: 5.70e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 142 YGKVGARLKTSHDAGVVTAFIMFSSVQ-----DEIDYEYVGNNLTQVQTNYYFEGVQNWTHSTNVStTDTFDNYHLYEVD 216
Cdd:cd02175   68 YGRYEVRMKPAKGSGVVSSFFTYTGPYdgdphDEIDIEFLGKDTTKVQFNYYTNGVGGHEKLIDLG-FDASEGFHTYAFE 146

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 238933750 217 WHEDHIDWLIDGEVSRTllknstfnATSGEYMFPQTPARIQISIWPGgnatnpVGTRSWAG 277
Cdd:cd02175  147 WEPDSIRWYVDGELVHE--------ATATDPNIPDTPGKIMMNLWPG------DGVDDWLG 193
BglS COG2273
Beta-glucanase, GH16 family [Carbohydrate transport and metabolism];
142-265 1.04e-16

Beta-glucanase, GH16 family [Carbohydrate transport and metabolism];


Pssm-ID: 441874 [Multi-domain]  Cd Length: 259  Bit Score: 79.65  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 142 YGKVGARLKTSHDAGVVTAFIMFSS-------VQDEID-YEYVGNNLTQVQTNYYFE---GVQNWTHSTNVSTTDTfDNY 210
Cdd:COG2273  107 YGRFEARAKLPKGQGLWPAFWMLGGdidggwpASGEIDiMEFVGKDPNKVHGNVHYGgynGGEGIGASYDLPFDAS-DDF 185

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 238933750 211 HLYEVDWHEDHIDWLIDGEVSRTLlknsTFNATSGEYMFpQTPARIQISIWPGGN 265
Cdd:COG2273  186 HTYAVEWTPDSIRWYVDGVLVHTV----TPADVGGPWPF-DQPFYLILNLAVGGN 235
Glyco_hydrolase_16 cd00413
glycosyl hydrolase family 16; The O-Glycosyl hydrolases are a widespread group of enzymes that ...
 84-282 3.38e-13

glycosyl hydrolase family 16; The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.


Pssm-ID: 185683 [Multi-domain]  Cd Length: 210  Bit Score: 68.62  E-value: 3.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750  84 FSNYSGDLQSQYTYLGDAEKHDWIYEGYTMDYDKEDALVLAMPKNSGGTVLSSTRYVW------YGKVGARLKTSHDAGV 157
Cdd:cd00413    3 FDGLALDTSKWTIQDGPSWGGNMTNSPNNVYVENDGGLTLRTDRDQTDGPYSSAEIDSqknnytYGYYEARAKLAGGPGA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 158 VTAFIMFSS-----VQDEIDYEYVGNNLTQVQTNY----YFEGVQNWTHSTNVSTTDTFDNYHLYEVDWHEDHIDWLIDG 228
Cdd:cd00413   83 VSAFWTYSDdddppDGGEIDIEFLGRDPTTVQTNVhwpgYGAGATTGEEKSVHLPFDPADDFHTYRVDWTPGEITFYVDG 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 238933750 229 EVSRTLlknstfnatsgEYMFPQTPARIQISIW-PGGNATNPVGTRSWAGGEINW 282
Cdd:cd00413  163 VLVATI-----------TNQVPDDPMNIILNLWsDGGWWWGGPPPGAPAYMEIDW 206
GH16_XET cd02176
Xyloglucan endotransglycosylase, member of glycosyl hydrolase family 16; Xyloglucan ...
 123-284 4.56e-11

Xyloglucan endotransglycosylase, member of glycosyl hydrolase family 16; Xyloglucan endotransglycosylases (XETs) cleave and religate xyloglucan polymers in plant cell walls via a transglycosylation mechanism. Xyloglucan is a soluble hemicellulose with a backbone of beta-1,4-linked glucose units, partially substituted with alpha-1,6-linked xylopyranose branches. It binds noncovalently to cellulose, cross-linking the adjacent cellulose microfibrils, giving it a key structural role as a matrix polymer. Therefore, XET plays an important role in all plant processes that require cell wall remodeling.


Pssm-ID: 185685 [Multi-domain]  Cd Length: 263  Bit Score: 62.99  E-value: 4.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 123 LAMPKNSGGTVLSSTRYVwYGKVGARLKTSHD--AGVVTAFIMFSS---VQDEIDYEYVGNNLTQ---VQTNYYFEGVQN 194
Cdd:cd02176   30 LTLDQSSGSGFKSKNKYL-FGFFSMRIKLPPGdsAGTVTAFYLSSQgpdNHDEIDFEFLGNVTGQpytLQTNVFANGVGG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 195 -------WthstnvsttdtFD---NYHLYEVDWHEDHIDWLIDGEVSRtLLKNstfNATSGEYmFP-QTPARIQISIWpg 263
Cdd:cd02176  109 reqriylW-----------FDptaDFHTYSILWNPHQIVFYVDDVPIR-VFKN---NEALGVP-YPsSQPMGVYASIW-- 170

                        170       180
                 ....*....|....*....|....*
gi 238933750 264 gNATnpvgtrSWA--GG--EINWDS 284
Cdd:cd02176  171 -DGS------DWAtqGGrvKIDWSY 188
GH16_laminarinase_like cd08023
Laminarinase, member of the glycosyl hydrolase family 16; Laminarinase, also known as glucan ...
 142-250 3.26e-08

Laminarinase, member of the glycosyl hydrolase family 16; Laminarinase, also known as glucan endo-1,3-beta-D-glucosidase, is a glycosyl hydrolase family 16 member that hydrolyzes 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans such as laminarins, curdlans, paramylons, and pachymans, with very limited action on mixed-link (1,3-1,4-)-beta-D-glucans.


Pssm-ID: 185693 [Multi-domain]  Cd Length: 235  Bit Score: 54.17  E-value: 3.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 142 YGKVGARLKTSHDAGVVTAFIM----FSSVQD----EID-YEYVGNNLTQVQTN----YYFEGVQNWTHSTNVSTTDTFD 208
Cdd:cd08023   79 YGRVEARAKLPKGQGTWPAFWMlgenIKYVGWpasgEIDiMEYVGNEPNTVYGTlhggATNDGNNGSGGSYTLPTDDLSD 158

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 238933750 209 NYHLYEVDWHEDHIDWLIDGEVSRTLlknsTFNATSGEYMFP 250
Cdd:cd08023  159 DFHTYAVEWTPDKITFYVDGKLYFTY----TNPNTDNGGQWP 196
ChtBD1 cd00035
Hevein or type 1 chitin binding domain; Hevein or type 1 chitin binding domain (ChtBD1), a ...
 35-63 2.79e-06

Hevein or type 1 chitin binding domain; Hevein or type 1 chitin binding domain (ChtBD1), a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins such as hevein, a major IgE-binding allergen in natural rubber latex, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.


Pssm-ID: 211311  Cd Length: 39  Bit Score: 43.91  E-value: 2.79e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 238933750  35 AACPEDkPCCSQYGVCGSG-SYCLGGCNPR 63
Cdd:cd00035    9 PPCPNN-LCCSQYGYCGTGdDYCGEGCQSQ 37
PLN03161 PLN03161
Probable xyloglucan endotransglucosylase/hydrolase protein; Provisional
 119-228 1.42e-05

Probable xyloglucan endotransglucosylase/hydrolase protein; Provisional


Pssm-ID: 178706 [Multi-domain]  Cd Length: 291  Bit Score: 46.82  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238933750 119 DALVLAMPKNSGGTVLSSTRYVwYGKVGARLK--TSHDAGVVTAFIMFS--SVQDEIDYEYVGNNLTQ---VQTNYYFEG 191
Cdd:PLN03161  47 DNLQLVLDQSSGSGIKSKRAFL-FGSIEMLIKlvPGNSAGTVTAYYLSStgSRHDEIDFEFLGNVSGQpytIHTNIYTQG 125

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 238933750 192 VQN-------WTHSTNvsttdtfdNYHLYEVDWHEDHIDWLIDG 228
Cdd:PLN03161 126 NGSreqqfrpWFDPTA--------DFHNYTIHWNPSEVVWYVDG 161
GH16_beta_GRP cd02179
beta-1,3-glucan recognition protein, member of glycosyl hydrolase family 16; Beta-GRP (beta-1, ...
 208-265 1.46e-03

beta-1,3-glucan recognition protein, member of glycosyl hydrolase family 16; Beta-GRP (beta-1,3-glucan recognition protein) is one of several pattern recognition receptors (PRRs), also referred to as biosensor proteins, that complexes with pathogen-associated beta-1,3-glucans and then transduces signals necessary for activation of an appropriate innate immune response. They are present in insects and lack all catalytic residues. This subgroup also contains related proteins of unknown function that still contain the active site. Their structures adopt a jelly roll fold with a deep active site channel harboring the catalytic residues, like those of other glycosyl hydrolase family 16 members.


Pssm-ID: 185688 [Multi-domain]  Cd Length: 321  Bit Score: 40.44  E-value: 1.46e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 238933750 208 DNYHLYEVDWHEDHIDWLIDGEVSRTLlknstfnaTSGEYMFPQTPARIQISIWPGGN 265
Cdd:cd02179  200 DDFHVYTLEWKPDGITLMVDGEEYGEI--------EPGEGGYSEAANNPAASRWLGGT 249
ChtBD1_1 cd11618
Hevein or type 1 chitin binding domain; filamentous ascomycete subfamily; Hevein or type 1 ...
 42-65 2.55e-03

Hevein or type 1 chitin binding domain; filamentous ascomycete subfamily; Hevein or type 1 chitin binding domain (ChtBD1), a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins such as hevein, a major IgE-binding allergen in natural rubber latex, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.


Pssm-ID: 211316  Cd Length: 44  Bit Score: 35.82  E-value: 2.55e-03
                         10        20
                 ....*....|....*....|....*
gi 238933750  42 PCCSQYGVCGS-GSYCLGGCNPRYS 65
Cdd:cd11618   17 NCCSAYGWCGNtSDHCGVGCQPGFG 41
ChtBD1 smart00270
Chitin binding domain;
37-61 3.45e-03

Chitin binding domain;


Pssm-ID: 214593  Cd Length: 38  Bit Score: 35.03  E-value: 3.45e-03
                           10        20
                   ....*....|....*....|....*.
gi 238933750    37 CPeDKPCCSQYGVCGSGS-YCLGGCN 61
Cdd:smart00270  11 CP-NNLCCSQFGYCGSGDeYCGRGCQ 35
GH16_CCF cd08024
Coelomic cytolytic factor, member of glycosyl hydrolase family 16; Subgroup of glucanases of ...
 193-265 3.46e-03

Coelomic cytolytic factor, member of glycosyl hydrolase family 16; Subgroup of glucanases of unknown function that are related to beta-GRP (beta-1,3-glucan recognition protein), but contain active site residues. Beta-GRPs are one group of pattern recognition receptors (PRRs), also referred to as biosensor proteins, that complexes with pathogen-associated beta-1,3-glucans and then transduces signals necessary for activation of an appropriate innate immune response. Beta-GRPs are present in insects and lack all catalytic residues. This subgroup contains related proteins that still contain the active site and are widely distributed in eukaryotes. Their structures adopt a jelly roll fold with a deep active site channel harboring the catalytic residues, like those of other glycosyl hydrolase family 16 members.


Pssm-ID: 185694  Cd Length: 330  Bit Score: 39.54  E-value: 3.46e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 238933750 193 QNWTHSTNVSTTDTF-DNYHLYEVDWHEDHIDWLIDGEVSRTL-LKNSTFNATSGeymFPQTPARiqiSIWPGGN 265
Cdd:cd08024  189 YTKTTGKRSDSGGDFaDDFHTYGLDWTPDHIRFYVDDRLILTLdVPGQGFWEFGG---FSGTPID---NPWAGGG 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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