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Conserved domains on  [gi|2054274370|emb|CAG2249191|]
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unnamed protein product [Mytilus edulis]

Protein Classification

zinc finger CCHC domain-containing protein( domain architecture ID 13284077)

zinc finger CCHC (ZCCHC) domain-containing protein contains a zinc knuckle or a zinc binding motif, CX2CX4HX4C, where X can be any amino acid, and may bind single-stranded RNA

Gene Ontology:  GO:0008270|GO:0003676
PubMed:  11179890|12665246|33787465

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 195-212 3.76e-07

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


:

Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 45.60  E-value: 3.76e-07
                          10
                  ....*....|....*...
gi 2054274370 195 GNCYNCGEEGHFSRDCKK 212
Cdd:pfam00098   1 GKCYNCGEPGHIARDCPK 18
PTZ00368 super family cl31762
universal minicircle sequence binding protein (UMSBP); Provisional
 174-223 6.34e-06

universal minicircle sequence binding protein (UMSBP); Provisional


The actual alignment was detected with superfamily member PTZ00368:

Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 45.57  E-value: 6.34e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2054274370 174 RSPQRTDRAFSPQRRYNSPARGN--CYNCGEEGHFSRDCkkPRNSSPYRNRS 223
Cdd:PTZ00368    5 RCGGVGHQSRECPNSAPAGAAKArpCYKCGEPGHLSREC--PSAPGGRGERS 54
 
Name Accession Description Interval E-value
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 195-212 3.76e-07

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 45.60  E-value: 3.76e-07
                          10
                  ....*....|....*...
gi 2054274370 195 GNCYNCGEEGHFSRDCKK 212
Cdd:pfam00098   1 GKCYNCGEPGHIARDCPK 18
ZnF_C2HC smart00343
zinc finger;
197-212 3.06e-06

zinc finger;


Pssm-ID: 197667 [Multi-domain]  Cd Length: 17  Bit Score: 43.20  E-value: 3.06e-06
                           10
                   ....*....|....*.
gi 2054274370  197 CYNCGEEGHFSRDCKK 212
Cdd:smart00343   2 CYNCGKEGHIARDCPS 17
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 185-214 3.37e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 46.34  E-value: 3.37e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 2054274370 185 PQRRYNSPARGNCYNCGEEGHFSRDCKKPR 214
Cdd:PTZ00368   94 PNRAKGGAARRACYNCGGEGHISRDCPNAG 123
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 174-223 6.34e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 45.57  E-value: 6.34e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2054274370 174 RSPQRTDRAFSPQRRYNSPARGN--CYNCGEEGHFSRDCkkPRNSSPYRNRS 223
Cdd:PTZ00368    5 RCGGVGHQSRECPNSAPAGAAKArpCYKCGEPGHLSREC--PSAPGGRGERS 54
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 173-219 2.76e-04

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 41.37  E-value: 2.76e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2054274370 173 SRSPQRTDRAFSPQRRYNSPARGNCYNCGEEGHFSRDCKKPRNSS-PY 219
Cdd:COG5082   133 SEDCPSIWKHYVLNNGDGHPIKKFCYSCGSAGHFGDDCKEPRSSRvPY 180
 
Name Accession Description Interval E-value
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 195-212 3.76e-07

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 45.60  E-value: 3.76e-07
                          10
                  ....*....|....*...
gi 2054274370 195 GNCYNCGEEGHFSRDCKK 212
Cdd:pfam00098   1 GKCYNCGEPGHIARDCPK 18
ZnF_C2HC smart00343
zinc finger;
197-212 3.06e-06

zinc finger;


Pssm-ID: 197667 [Multi-domain]  Cd Length: 17  Bit Score: 43.20  E-value: 3.06e-06
                           10
                   ....*....|....*.
gi 2054274370  197 CYNCGEEGHFSRDCKK 212
Cdd:smart00343   2 CYNCGKEGHIARDCPS 17
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 185-214 3.37e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 46.34  E-value: 3.37e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 2054274370 185 PQRRYNSPARGNCYNCGEEGHFSRDCKKPR 214
Cdd:PTZ00368   94 PNRAKGGAARRACYNCGGEGHISRDCPNAG 123
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 174-223 6.34e-06

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 45.57  E-value: 6.34e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2054274370 174 RSPQRTDRAFSPQRRYNSPARGN--CYNCGEEGHFSRDCkkPRNSSPYRNRS 223
Cdd:PTZ00368    5 RCGGVGHQSRECPNSAPAGAAKArpCYKCGEPGHLSREC--PSAPGGRGERS 54
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 197-223 1.92e-04

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 41.33  E-value: 1.92e-04
                          10        20
                  ....*....|....*....|....*..
gi 2054274370 197 CYNCGEEGHFSRDCkkPRNSSPYRNRS 223
Cdd:PTZ00368   55 CYNCGKTGHLSREC--PEAPPGSGPRS 79
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 173-219 2.76e-04

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 41.37  E-value: 2.76e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2054274370 173 SRSPQRTDRAFSPQRRYNSPARGNCYNCGEEGHFSRDCKKPRNSS-PY 219
Cdd:COG5082   133 SEDCPSIWKHYVLNNGDGHPIKKFCYSCGSAGHFGDDCKEPRSSRvPY 180
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 185-214 2.95e-04

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 40.56  E-value: 2.95e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 2054274370 185 PQRRYNSPARgNCYNCGEEGHFSRDCKKPR 214
Cdd:PTZ00368   69 PEAPPGSGPR-SCYNCGQTGHISRECPNRA 97
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 190-211 1.43e-03

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 38.63  E-value: 1.43e-03
                          10        20
                  ....*....|....*....|....*.
gi 2054274370 190 NSPARG----NCYNCGEEGHFSRDCK 211
Cdd:PTZ00368  121 NAGKRPggdkTCYNCGQTGHLSRDCP 146
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 196-218 1.46e-03

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 38.63  E-value: 1.46e-03
                          10        20
                  ....*....|....*....|...
gi 2054274370 196 NCYNCGEEGHFSRDCKKPRNSSP 218
Cdd:PTZ00368    2 VCYRCGGVGHQSRECPNSAPAGA 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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