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Conserved domains on  [gi|1681040857|dbj|BBK91468|]
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hypothetical protein DN0286_17540 [Parabacteroides distasonis]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 super family cl41295
IS3 family transposase;
2-108 6.75e-07

IS3 family transposase;


The actual alignment was detected with superfamily member NF033516:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 46.40  E-value: 6.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWER-YFESKTLSLPSDLTELehqvymarkksesskatgpqteSERLR 80
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKkYRGGGEAADAGRLKEL----------------------LTPEE 58

                          90       100
                  ....*....|....*....|....*...
gi 1681040857  81 EENLRLRKALAYSELRNEALHELLKIGR 108
Cdd:NF033516   59 EENRRLKRELAELRLENEILKKARKLLR 86
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
2-108 6.75e-07

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 46.40  E-value: 6.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWER-YFESKTLSLPSDLTELehqvymarkksesskatgpqteSERLR 80
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKkYRGGGEAADAGRLKEL----------------------LTPEE 58

                          90       100
                  ....*....|....*....|....*...
gi 1681040857  81 EENLRLRKALAYSELRNEALHELLKIGR 108
Cdd:NF033516   59 EENRRLKRELAELRLENEILKKARKLLR 86
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 2-62 4.50e-04

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 36.18  E-value: 4.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWERYFESKTLSLP--SDLTELEHQVYMARK 62
Cdd:pfam01527  10 EFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGASParPRLTALEEENRRLKR 72
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-92 5.13e-04

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 36.44  E-value: 5.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWERYFESKTLSLPSDltelehqvyMARKKSESSKATGPQTESERLRE 81
Cdd:COG2963    11 EFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPG---------DGRTTPEQAEIRRLRKELRRLEM 81

                          90
                  ....*....|.
gi 1681040857  82 ENLRLRKALAY 92
Cdd:COG2963    82 ENDILKKAAAL 92
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
2-108 6.75e-07

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 46.40  E-value: 6.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWER-YFESKTLSLPSDLTELehqvymarkksesskatgpqteSERLR 80
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKkYRGGGEAADAGRLKEL----------------------LTPEE 58

                          90       100
                  ....*....|....*....|....*...
gi 1681040857  81 EENLRLRKALAYSELRNEALHELLKIGR 108
Cdd:NF033516   59 EENRRLKRELAELRLENEILKKARKLLR 86
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 2-62 4.50e-04

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 36.18  E-value: 4.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWERYFESKTLSLP--SDLTELEHQVYMARK 62
Cdd:pfam01527  10 EFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGASParPRLTALEEENRRLKR 72
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
2-92 5.13e-04

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 36.44  E-value: 5.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1681040857   2 EFKLRMLKEYYESGSTKYSLCKKYSVDYVTFSRWERYFESKTLSLPSDltelehqvyMARKKSESSKATGPQTESERLRE 81
Cdd:COG2963    11 EFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPG---------DGRTTPEQAEIRRLRKELRRLEM 81

                          90
                  ....*....|.
gi 1681040857  82 ENLRLRKALAY 92
Cdd:COG2963    82 ENDILKKAAAL 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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