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Conserved domains on  [gi|781880126|dbj|BAR04368|]
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ABC transporter permease component [Bifidobacterium pseudocatenulatum DSM 20438 = JCM 1200 = LMG 10505]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 34-319 8.20e-86

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 259.26  E-value: 8.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  34 RSMRPSPITKTITVIVLVVALIYFLFPIYWAIIASTKTPSQLTSSNGLWFAVGLDqipdaiATNYSKLmgWTRGQFWRWV 113
Cdd:COG0395    5 ARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFT------LENYRAA--FTDGPFGRYL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCV--S 191
Cdd:COG0395   77 LNSLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 192 PFGFFLGRVYAQtSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPVTLGL 271
Cdd:COG0395  157 PFGIFLLRQFFR-SIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGL 235

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 781880126 272 YGMVSLATfNDRGSLMMGALLGVLPVIVLFLGLQRYWQAGLAAGAVKG 319
Cdd:COG0395  236 ASFQGQYG-TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 34-319 8.20e-86

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 259.26  E-value: 8.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  34 RSMRPSPITKTITVIVLVVALIYFLFPIYWAIIASTKTPSQLTSSNGLWFAVGLDqipdaiATNYSKLmgWTRGQFWRWV 113
Cdd:COG0395    5 ARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFT------LENYRAA--FTDGPFGRYL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCV--S 191
Cdd:COG0395   77 LNSLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 192 PFGFFLGRVYAQtSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPVTLGL 271
Cdd:COG0395  157 PFGIFLLRQFFR-SIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGL 235

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 781880126 272 YGMVSLATfNDRGSLMMGALLGVLPVIVLFLGLQRYWQAGLAAGAVKG 319
Cdd:COG0395  236 ASFQGQYG-TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
49-312 1.97e-29

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 113.68  E-value: 1.97e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  49 VLVVALIYFLFPIYWAIIASTKTPSQLtssnglwFAVGLDQIP-----DAIATNYSKLMGWTRGQFWRWVLNSLIYSGVS 123
Cdd:PRK10973  15 MLILGIAVILFPLYVAFVAATLDKQAV-------FAVPMTLIPgthllENIANIWVNGVGNNSAPFGRMLLNSFVMAFSI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 124 ALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVSPFGFFLGRVYAQ 203
Cdd:PRK10973  88 TVGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFM 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 204 TsVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPVTLGLYGMVSLATFNDR 283
Cdd:PRK10973 168 T-LPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEGTTE 246

                        250       260       270
                 ....*....|....*....|....*....|
gi 781880126 284 GSLMMGA-LLGVLPVIVLFLGLQRYWQAGL 312
Cdd:PRK10973 247 WNQVMAAmLLTLIPPVVIVLAMQRAFVRGL 276
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 114-298 1.82e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.39  E-value: 1.82e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVSPF 193
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 194 GFFLG-----RVYAQTSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPvT 268
Cdd:cd06261   82 LLIAPfarliRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP-G 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 781880126 269 LGLYGMVSLATFNDRGSLMMGALLGVLPVI 298
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 127-307 4.44e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.08  E-value: 4.44e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  127 GTIISVMAGYataKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVSPFGFFLG-RVYAQTS 205
Cdd:pfam00528   1 GIPLGIIAAL---RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLiRRAALRS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  206 VPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTL-KPVTLGLYGMVslatFNDRG 284
Cdd:pfam00528  78 LPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLgLLLIEAILGYD----YPEIQ 153

                         170       180
                  ....*....|....*....|...
gi 781880126  285 SLMMGALLGVLPVIVLFLGLQRY 307
Cdd:pfam00528 154 GPVLAAALILLLLNLLVDILQRL 176
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 34-319 8.20e-86

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 259.26  E-value: 8.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  34 RSMRPSPITKTITVIVLVVALIYFLFPIYWAIIASTKTPSQLTSSNGLWFAVGLDqipdaiATNYSKLmgWTRGQFWRWV 113
Cdd:COG0395    5 ARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFT------LENYRAA--FTDGPFGRYL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCV--S 191
Cdd:COG0395   77 LNSLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 192 PFGFFLGRVYAQtSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPVTLGL 271
Cdd:COG0395  157 PFGIFLLRQFFR-SIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGL 235

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 781880126 272 YGMVSLATfNDRGSLMMGALLGVLPVIVLFLGLQRYWQAGLAAGAVKG 319
Cdd:COG0395  236 ASFQGQYG-TDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 34-319 5.87e-59

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 190.75  E-value: 5.87e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  34 RSMRPSPITKTITVIVLVVALIYFLFPIYWAIIASTKTPSQLTSSNGLWFAVGLDqipdaiatNYSKLMgwTRGQFWRWV 113
Cdd:COG3833    6 SRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLIPENFTLE--------NYKKLF--TETPFLRWF 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVS-- 191
Cdd:COG3833   76 LNSLIVAVVTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGai 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 192 PFGFFLGRVYAQTsVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPVTLGL 271
Cdd:COG3833  156 PFNTWLMKGYFDT-IPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGL 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 781880126 272 YGMVSLATFNDRGSLMMGALLGVLPVIVLFLGLQRYWQAGLAAGAVKG 319
Cdd:COG3833  235 YSFVSDQRNTNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
49-312 1.97e-29

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 113.68  E-value: 1.97e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  49 VLVVALIYFLFPIYWAIIASTKTPSQLtssnglwFAVGLDQIP-----DAIATNYSKLMGWTRGQFWRWVLNSLIYSGVS 123
Cdd:PRK10973  15 MLILGIAVILFPLYVAFVAATLDKQAV-------FAVPMTLIPgthllENIANIWVNGVGNNSAPFGRMLLNSFVMAFSI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 124 ALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVSPFGFFLGRVYAQ 203
Cdd:PRK10973  88 TVGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFM 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 204 TsVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPVTLGLYGMVSLATFNDR 283
Cdd:PRK10973 168 T-LPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEGTTE 246

                        250       260       270
                 ....*....|....*....|....*....|
gi 781880126 284 GSLMMGA-LLGVLPVIVLFLGLQRYWQAGL 312
Cdd:PRK10973 247 WNQVMAAmLLTLIPPVVIVLAMQRAFVRGL 276
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 39-307 3.11e-21

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 90.94  E-value: 3.11e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  39 SPITKTITVIVLVVALIYFLFPIYWAIIASTKTPSQLTssnGLWFAVGLDqipdaiatNYSKLmgWTRGQFWRWVLNSLI 118
Cdd:COG1177    2 SRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWFLT---FPPEGFTLR--------WYAEL--FSDPRLLDALLNSLL 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 119 YSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCV--SPFGFF 196
Cdd:COG1177   69 IALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVftLPFVVL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 197 LgrVYAQ-TSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTlkpVTLGLYgMV 275
Cdd:COG1177  149 V--VLARlQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGV---TTLPVY-IY 222

                        250       260       270
                 ....*....|....*....|....*....|..
gi 781880126 276 SLATFNDRGSLMMGALLGVLPVIVLFLGLQRY 307
Cdd:COG1177  223 SMIRRGISPEINALSTLLILLSLLLLLLAERL 254
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
50-258 6.21e-17

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 79.41  E-value: 6.21e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  50 LVVALIYFLFPIYWAIIASTkTPSQLTSSNGLWfaVGLDqipdaiatNYSKLmgWTRGQFWRWVLNSLIYSGVSALIGTI 129
Cdd:COG1175   28 LLLLLVFVLYPLLYTLYLSF-TDWNLLGPPPEF--VGLD--------NYARL--FTDPRFWNALGNTLLFTVVSVPLQLV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 130 ISVMAGYATAKfNFRGKAIAIGVVMGCMLMPVALLTI-------PQY----SIFHALHLTNT---------MLAIIIPCC 189
Cdd:COG1175   95 LGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALiwkwlfnPDYgllnALLGALGLEPInwlgdpslaLPAVIIVTV 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 781880126 190 VSPFGF----FLGrvyAQTSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMM 258
Cdd:COG1175  174 WKGTGFnmliFLA---GLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYVL 243
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-304 1.00e-16

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 80.59  E-value: 1.00e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  12 RARRKAERMMEKQREAAehdlPRSMRPSPITKTITVIVLVVALIYFLFPIYWAIIASTKTPSQLTSSNGLWFAVGLDqip 91
Cdd:COG1178  261 RLRRRRRYATVGGRARR----PRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTKALDDNLTLDNYRFVLLD--- 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  92 daiatnysklmgwtrGQFWRWVLNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMP-----VALLTI 166
Cdd:COG1178  334 ---------------PSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPgivlgLGLLLL 398

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 167 pqYSIFHALHLTNTMLAIIIPCCV--SPFGFFLGRVyAQTSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFL 244
Cdd:COG1178  399 --FNRPLPLLLYGTLAILVLAYVVrfLPFALRSLEA-ALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLV 475

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 245 FVGTWNNFLLPLMMVSSDTlkpVTLGLYgmvsLATFNDRGSLMMGALLGVLPVIVLFLGL 304
Cdd:COG1178  476 FVTSMKELSATLLLRPPGF---ETLAVL----IYQLASSGRYGEAAALALLLVLVSLLPV 528
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 114-298 1.82e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.39  E-value: 1.82e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVSPF 193
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 194 GFFLG-----RVYAQTSVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLKPvT 268
Cdd:cd06261   82 LLIAPfarliRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP-G 160

                        170       180       190
                 ....*....|....*....|....*....|
gi 781880126 269 LGLYGMVSLATFNDRGSLMMGALLGVLPVI 298
Cdd:cd06261  161 TGLLLIFAILFPGDLGVAAAVALILLLLSL 190
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
104-319 9.56e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.57  E-value: 9.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 104 WTRGQFWRWVLNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLA 183
Cdd:COG1178   47 LSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLR 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 184 IIIPCCVSPFGFFLGRVYAQT----------------SVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVG 247
Cdd:COG1178  127 ALFGLEPPDIYGLGGIILVLVlfnypyvylllraalrSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLL 206

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 781880126 248 TWNNFLLPLMM-VSSDTLkpvTLGLYgmvslATFNDRGSLMMGALLGV--LPVIVLFLGLQRYWQAGLAAGAVKG 319
Cdd:COG1178  207 CLADFGTPLVLgGGYTTL---TTAIY-----QAWLGDFDLGAAAALALvlLLLVLLLLLLERRLRRRRRYATVGG 273
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 127-307 4.44e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.08  E-value: 4.44e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  127 GTIISVMAGYataKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTNTMLAIIIPCCVSPFGFFLG-RVYAQTS 205
Cdd:pfam00528   1 GIPLGIIAAL---RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLiRRAALRS 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  206 VPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTL-KPVTLGLYGMVslatFNDRG 284
Cdd:pfam00528  78 LPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLgLLLIEAILGYD----YPEIQ 153

                         170       180
                  ....*....|....*....|...
gi 781880126  285 SLMMGALLGVLPVIVLFLGLQRY 307
Cdd:pfam00528 154 GPVLAAALILLLLNLLVDILQRL 176
malG PRK10998
maltose ABC transporter permease MalG;
111-319 4.54e-10

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 59.72  E-value: 4.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 111 RWVLNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHL------TNTMLAI 184
Cdd:PRK10998  83 LWLWNSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQyipfigLNTHGGV 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 185 IIPccvspfgfFLGRV---------YAQTsVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFllP 255
Cdd:PRK10998 163 IFA--------YLGGIalhvwtikgYFET-IDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEV--P 231

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 781880126 256 LMMVSSDTLKPVTLGLYGMVSLATFNDR-GSLMMGALLGVLPVIVLFLGLQRYWQAGLAAGAVKG 319
Cdd:PRK10998 232 VASLLLRDVNSYTLAVGMQQYLNPQNYLwGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVKG 296
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 49-304 1.51e-09

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 57.85  E-value: 1.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126  49 VLVVALIYFLFPIYWAIIASTKTPSQLTssnGLWFAVGLDqipdaiatNYSKLmgWTRGQFWRWVLNSLIYSGVSALIGT 128
Cdd:COG1176   18 ALLWLLLFFVLPLLLLLVYSFTTRDPYG---GVVPGFTLE--------NYARL--FTDPLYLKVLLRTLWIALLTTLICL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 129 IISVMAGYATAKFNFRGKAIAIGVVMGCMLMPV-----ALLTIPQY-----SIFHALHLTNTMLAIIipccVSPFGFFLG 198
Cdd:COG1176   85 LLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFlvrtyAWIVLLGRngllnSLLLALGLIDEPLRLL----YTEFAVVIG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 199 RVYAQT------------SVPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLFVGTWNNFLLPLMMVSSDTLkp 266
Cdd:COG1176  161 LVYVYLpfmvlplyaaleKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVL-- 238

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 781880126 267 vtlgLYGMVSLATFNDRGSLMMGALLGVLPVIVLFLGL 304
Cdd:COG1176  239 ----MIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVL 272
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 114-245 3.89e-07

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 50.37  E-value: 3.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781880126 114 LNSLIYSGVSALIGTIISVMAGYATAKFNFRGKAIAIGVVMGCMLMPVALLTIPQYSIFHALHLTN---TMLAIIIPCCV 190
Cdd:PRK09500  60 QHSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLgfwSLLFAHITFCL 139

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 781880126 191 SpfgFFLGRVYAQTS-VPNELLEAARIDGAGEARIFFTIVLRLLAPAMVTIFLFLF 245
Cdd:PRK09500 140 P---FVVVTVYSRLKgFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSF 192
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
193-244 5.00e-04

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 40.96  E-value: 5.00e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 781880126 193 FGFFLGrvyAQTSVPNELLEAARIDGAGEARIFFTIVLRLLAPamVTIFLFL 244
Cdd:PRK10561 159 FLFFFA---ALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAP--VSFFLLV 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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