|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
1-528 |
0e+00 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 599.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 1 MAMDHTVKVILGSIAFATFWLLAVFPAIPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLE 80
Cdd:PLN00136 1 MALASLPKVVLGSLAFGVFWMLAVFPSVPFLPIGRTAGALLSAVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 81 RADMFKYLGKVLSWRSKGAKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATP 160
Cdd:PLN00136 81 NAGMFKHLGRLLAWRSQGGRDLLCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 161 IGNPQNLVIAVQSKIPFGEFVVGILPAMLVGVVVNALIILILYWKLLSVQKDEEDPSSEIVADEVVLSHrfsparlshtq 240
Cdd:PLN00136 161 IGNPQNLVIAFNSKITFPKFLLGILPAMLAGMAVNMVMLLCMYWKDLDGGAELSVDGKQMEAVEEGRSP----------- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 241 ipslnspewesrldsmnanvetqRSVSSKENEIHRSHSALTESARISDASSLkREEGFSSKSLNSMDkqkesvslpSSEE 320
Cdd:PLN00136 230 -----------------------ASAKSTKQQSPALLQAGLNGDGNGDMSSM-MSENISTKHPWFMQ---------CTEH 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 321 KehwstkwRRIAWKCCVYLVTIGMLVALLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNK 400
Cdd:PLN00136 277 R-------RKLFLKSFAYVVTVGMVVAYMVGLNMSWTAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFITVSGFNK 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 401 TGLPSAFWDFMEPHAQIDRVSGTVVLALVILYLSNLASNVPTVLLLGARVAASAAAISPMEEKRAWLLLAWISTVAGNLS 480
Cdd:PLN00136 350 TGLPGAIWNFMAPYSKVNSVGGISVLSVIILLLSNLASNVPTVLLMGDEVAAAAALISPAAVTRSWLLLAWVSTVAGNLS 429
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 327187686 481 LLGSAANLIVCEQARRTPQLSYNLSFWNHLKFGVPSTLIVTAIGLVLI 528
Cdd:PLN00136 430 LLGSAANLIVCEQARRAPRNAYDLTFWQHIVFGVPSTLIVTAIGIPLI 477
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
28-528 |
1.05e-110 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 334.25 E-value: 1.05e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 28 IPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWRSKGAKDLICRVC 107
Cdd:cd01117 6 VPGLRLDRWAIALLGAALMLLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFLLV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 108 LISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKIPFGEFVVGILPA 187
Cdd:cd01117 86 LLSGILSALLTNDTACLVFTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 188 MLVGVVVNALIILILYWKLLSVQKDEEDPSSEIVadevvlshrfsparlshtqipslnspewesrldsmnanvetqrsvs 267
Cdd:cd01117 166 ALLGLLLLLILLLVLFPGELKGLPLDKATKEEGV---------------------------------------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 268 skeneihrshsaltesarisdasslkreegfsskslnsmdkqkesvslpsseekehwstKWRRIAWKCCVYLVTIGMLVA 347
Cdd:cd01117 200 -----------------------------------------------------------GARKLAVKLLVLILLLLVAFL 220
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 348 LLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNkTGLPSAFWDFMEPHaqidrVSGTVVLA 427
Cdd:cd01117 221 ALLGVIPLWTAALVAAVLLLLTRLKPRRVLKKVDWGLLLFFAGLFILVGGFA-QGLPLEGLSRLLPL-----LDSVLSLF 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 428 LVILYLSNLASNVPTVLLLGarvaasaaAISPMEEKRAWLLLAWISTVAGNLSLLGSAANLIVCEQARRTpqlSYNLSFW 507
Cdd:cd01117 295 LVSIGLSQLISNVPAVLLLL--------PFLPSADEKDWLLLAAGSTIAGNLTLLGSAANLIVAEAAERR---GVRLSFG 363
|
490 500
....*....|....*....|.
gi 327187686 508 NHLKFGVPSTLIVTAIGLVLI 528
Cdd:cd01117 364 EFLKYGVPLTLLTAAIGILWL 384
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
9-528 |
2.18e-74 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 241.57 E-value: 2.18e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 9 VILGSIAFATFWLLAVFPaipfLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYL 88
Cdd:COG1055 3 ILALAIFVLTYLLIILEP----RGLNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 89 GKVLSWRSKGAKD-LICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNL 167
Cdd:COG1055 79 AIKLARRAKGSPRrLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 168 VIAVQSKIPFGEFVVGILPAMLVGVVVNALIILILYWKLLSVQKDEEDPSSEIVADevvlshrfsparlshtqipslnsp 247
Cdd:COG1055 159 MIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLEDDPKEAIKD------------------------ 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 248 ewesrldsmnanvetqrsvsskeneihrshsaltesarisdasslkreegfsskslnsmdkqkesvslpsseekehwstk 327
Cdd:COG1055 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 328 wRRIAWKCCVYLVTI--GMLVALLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPS 405
Cdd:COG1055 215 -RRLLRISLLVLALLlvGFVLHSFLGLPPALIALLGAAVLLLLARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLD 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 406 AFWDFMEPHAQIDRVSGTVVLALVILYLSNLASNVPTVLLLGARVAASAAAISPMEekrAWLLLAWISTVAGNLSLLGSA 485
Cdd:COG1055 294 LLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPEP---LWLALALGATLGGNLTPIGSA 370
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 327187686 486 ANLIVCEQARRtpqLSYNLSFWNHLKFGVPSTLIVTAIGLVLI 528
Cdd:COG1055 371 ANVIVLGIAEK---KGIKISFGEFLKVGLPLTLLTLLIALLYL 410
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
32-476 |
3.15e-63 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 209.86 E-value: 3.15e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 32 PVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWRSKGAKD-LICRVCLIS 110
Cdd:pfam03600 8 KLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRrLLVALMLAT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 111 AISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKIPFGEFVVGILPAMLV 190
Cdd:pfam03600 88 ALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 191 GVVVNALIILIL-YWKLLSVQKDEEDPsseivadevvlshrfsparlshtqipslnspewesrldsmnanvetqrsvssk 269
Cdd:pfam03600 168 ALLLVGLLPLLLiFRKLLPVRKEEEAE----------------------------------------------------- 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 270 eneihrshsaltesarisdasslkreegfsskslnsmdkqkesvslpsSEEKEHWSTKWRRIAWKCCVYLVTIGMLVALL 349
Cdd:pfam03600 195 ------------------------------------------------LEELRKRAIKDKLLLAISALVLALVILGFLLL 226
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 350 MGLNMSWtavtaALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMEPHAQIdrVSGTVVLALV 429
Cdd:pfam03600 227 SVLALAG-----ALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLSGL--LVALALILWL 299
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 327187686 430 ILYLSNLASNVPTVLLLGarvaASAAAISPMEEKRAWLLLAWISTVA 476
Cdd:pfam03600 300 SALLSAFISNVPTAALMA----PIIVGMAPAAGLGDPDPLAWALAVG 342
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
16-204 |
4.30e-04 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 42.72 E-value: 4.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 16 FATFW--LLAVFPAI--PFLPVGRTAGSLLGAMLMVVFRVLTPDQAYA-AIDLPILGLLFGTMVVSVYLERADMFKYLGK 90
Cdd:TIGR00785 249 KALLGifLLALLLWIfgGSLGINASVVALLAVVLMLFLGIVTWKDIQKnKVAWNTLILFGGLIGLAGGLKKSGFIKWFSE 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 91 VLSWRSKG---AKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNL 167
Cdd:TIGR00785 329 KLVGILDGlspTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMGFLTPYATPPNA 408
|
170 180 190
....*....|....*....|....*....|....*..
gi 327187686 168 VIAVQSKIPFGEFVVGILPAMLVGVVVNALIIlILYW 204
Cdd:TIGR00785 409 IAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVG-TLWW 444
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
1-528 |
0e+00 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 599.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 1 MAMDHTVKVILGSIAFATFWLLAVFPAIPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLE 80
Cdd:PLN00136 1 MALASLPKVVLGSLAFGVFWMLAVFPSVPFLPIGRTAGALLSAVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 81 RADMFKYLGKVLSWRSKGAKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATP 160
Cdd:PLN00136 81 NAGMFKHLGRLLAWRSQGGRDLLCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 161 IGNPQNLVIAVQSKIPFGEFVVGILPAMLVGVVVNALIILILYWKLLSVQKDEEDPSSEIVADEVVLSHrfsparlshtq 240
Cdd:PLN00136 161 IGNPQNLVIAFNSKITFPKFLLGILPAMLAGMAVNMVMLLCMYWKDLDGGAELSVDGKQMEAVEEGRSP----------- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 241 ipslnspewesrldsmnanvetqRSVSSKENEIHRSHSALTESARISDASSLkREEGFSSKSLNSMDkqkesvslpSSEE 320
Cdd:PLN00136 230 -----------------------ASAKSTKQQSPALLQAGLNGDGNGDMSSM-MSENISTKHPWFMQ---------CTEH 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 321 KehwstkwRRIAWKCCVYLVTIGMLVALLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNK 400
Cdd:PLN00136 277 R-------RKLFLKSFAYVVTVGMVVAYMVGLNMSWTAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFITVSGFNK 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 401 TGLPSAFWDFMEPHAQIDRVSGTVVLALVILYLSNLASNVPTVLLLGARVAASAAAISPMEEKRAWLLLAWISTVAGNLS 480
Cdd:PLN00136 350 TGLPGAIWNFMAPYSKVNSVGGISVLSVIILLLSNLASNVPTVLLMGDEVAAAAALISPAAVTRSWLLLAWVSTVAGNLS 429
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 327187686 481 LLGSAANLIVCEQARRTPQLSYNLSFWNHLKFGVPSTLIVTAIGLVLI 528
Cdd:PLN00136 430 LLGSAANLIVCEQARRAPRNAYDLTFWQHIVFGVPSTLIVTAIGIPLI 477
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
28-528 |
1.05e-110 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 334.25 E-value: 1.05e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 28 IPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWRSKGAKDLICRVC 107
Cdd:cd01117 6 VPGLRLDRWAIALLGAALMLLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSPRRLLFLLV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 108 LISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKIPFGEFVVGILPA 187
Cdd:cd01117 86 LLSGILSALLTNDTACLVFTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLLIASESGISFPFFLAAMAPL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 188 MLVGVVVNALIILILYWKLLSVQKDEEDPSSEIVadevvlshrfsparlshtqipslnspewesrldsmnanvetqrsvs 267
Cdd:cd01117 166 ALLGLLLLLILLLVLFPGELKGLPLDKATKEEGV---------------------------------------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 268 skeneihrshsaltesarisdasslkreegfsskslnsmdkqkesvslpsseekehwstKWRRIAWKCCVYLVTIGMLVA 347
Cdd:cd01117 200 -----------------------------------------------------------GARKLAVKLLVLILLLLVAFL 220
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 348 LLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNkTGLPSAFWDFMEPHaqidrVSGTVVLA 427
Cdd:cd01117 221 ALLGVIPLWTAALVAAVLLLLTRLKPRRVLKKVDWGLLLFFAGLFILVGGFA-QGLPLEGLSRLLPL-----LDSVLSLF 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 428 LVILYLSNLASNVPTVLLLGarvaasaaAISPMEEKRAWLLLAWISTVAGNLSLLGSAANLIVCEQARRTpqlSYNLSFW 507
Cdd:cd01117 295 LVSIGLSQLISNVPAVLLLL--------PFLPSADEKDWLLLAAGSTIAGNLTLLGSAANLIVAEAAERR---GVRLSFG 363
|
490 500
....*....|....*....|.
gi 327187686 508 NHLKFGVPSTLIVTAIGLVLI 528
Cdd:cd01117 364 EFLKYGVPLTLLTAAIGILWL 384
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
9-528 |
2.18e-74 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 241.57 E-value: 2.18e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 9 VILGSIAFATFWLLAVFPaipfLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYL 88
Cdd:COG1055 3 ILALAIFVLTYLLIILEP----RGLNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 89 GKVLSWRSKGAKD-LICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNL 167
Cdd:COG1055 79 AIKLARRAKGSPRrLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 168 VIAVQSKIPFGEFVVGILPAMLVGVVVNALIILILYWKLLSVQKDEEDPSSEIVADevvlshrfsparlshtqipslnsp 247
Cdd:COG1055 159 MIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPAAPDLEDDPKEAIKD------------------------ 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 248 ewesrldsmnanvetqrsvsskeneihrshsaltesarisdasslkreegfsskslnsmdkqkesvslpsseekehwstk 327
Cdd:COG1055 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 328 wRRIAWKCCVYLVTI--GMLVALLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPS 405
Cdd:COG1055 215 -RRLLRISLLVLALLlvGFVLHSFLGLPPALIALLGAAVLLLLARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLD 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 406 AFWDFMEPHAQIDRVSGTVVLALVILYLSNLASNVPTVLLLGARVAASAAAISPMEekrAWLLLAWISTVAGNLSLLGSA 485
Cdd:COG1055 294 LLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPEP---LWLALALGATLGGNLTPIGSA 370
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 327187686 486 ANLIVCEQARRtpqLSYNLSFWNHLKFGVPSTLIVTAIGLVLI 528
Cdd:COG1055 371 ANVIVLGIAEK---KGIKISFGEFLKVGLPLTLLTLLIALLYL 410
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
28-528 |
6.12e-73 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 237.15 E-value: 6.12e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 28 IPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWRSKGAKDLICRVC 107
Cdd:cd00625 4 IRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRLLLLLM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 108 LISAISSAFFTNDTSCVVLTEFVLKIARQHNL-PPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKIPFGEFVVGILP 186
Cdd:cd00625 84 LLTAALSAFFSNDATAVLLTPIVLALLRKLGLsPPVPLLLALAFAANIGGAATPIGNPPNLIIASLSGLGFLDFLAFMAP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 187 AMLVGVVVNALIILILYWKLLSvqkdeedpsseivadevvlshrfsparlshtqipslnspewesrldsmnanvetqrsv 266
Cdd:cd00625 164 PALGLLLLLLGLLYLLFRKKLL---------------------------------------------------------- 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 267 sskeneihrshsaltesarisdasslkreegfsskslnsmdKQKESVSLPSSEEKEHWSTKWRRIAWKCCVYLVTIGMLV 346
Cdd:cd00625 186 -----------------------------------------LPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFF 224
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 347 ALlmGLNMSWTAVTAALALVVLDF-KDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMEPHAQIDRVSGTVV 425
Cdd:cd00625 225 FL--IPLGLIALLGALLLLLLLVRgLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLL 302
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 426 LALVILYLSNLASNVPTVLLLgarvaaSAAAISPMEEKRAWLLLAWISTVAGNLSLLGSAANLIVCEQARRTpqlSYNLS 505
Cdd:cd00625 303 IGLLSALLSNFISNVPTVALL------LPIAASLAPPEPAWLALALGSTLGGNLTLIGSLANLIPLGAAENA---GVGIS 373
|
490 500
....*....|....*....|...
gi 327187686 506 FWNHLKFGVPSTLIVTAIGLVLI 528
Cdd:cd00625 374 FGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
32-476 |
3.15e-63 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 209.86 E-value: 3.15e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 32 PVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWRSKGAKD-LICRVCLIS 110
Cdd:pfam03600 8 KLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRrLLVALMLAT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 111 AISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKIPFGEFVVGILPAMLV 190
Cdd:pfam03600 88 ALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 191 GVVVNALIILIL-YWKLLSVQKDEEDPsseivadevvlshrfsparlshtqipslnspewesrldsmnanvetqrsvssk 269
Cdd:pfam03600 168 ALLLVGLLPLLLiFRKLLPVRKEEEAE----------------------------------------------------- 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 270 eneihrshsaltesarisdasslkreegfsskslnsmdkqkesvslpsSEEKEHWSTKWRRIAWKCCVYLVTIGMLVALL 349
Cdd:pfam03600 195 ------------------------------------------------LEELRKRAIKDKLLLAISALVLALVILGFLLL 226
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 350 MGLNMSWtavtaALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMEPHAQIdrVSGTVVLALV 429
Cdd:pfam03600 227 SVLALAG-----ALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGLSGL--LVALALILWL 299
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 327187686 430 ILYLSNLASNVPTVLLLGarvaASAAAISPMEEKRAWLLLAWISTVA 476
Cdd:pfam03600 300 SALLSAFISNVPTAALMA----PIIVGMAPAAGLGDPDPLAWALAVG 342
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
21-526 |
5.50e-35 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 135.84 E-value: 5.50e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 21 LLAVFPAIPFLPVGRTAGSLLGAMLMVVFRV----LTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWRS 96
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLVILGLatlsPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 97 KG-AKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKI 175
Cdd:cd01116 81 KGrPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGSAAGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 176 PFGEFVVGILPAMLVGVVVNALIILILYWKLLSVQKDEEDPSSEivadevvlshrfsparlshtqipslnspewesrlds 255
Cdd:cd01116 161 TFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALAE------------------------------------ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 256 mnanvetqrsvsskeneihrshsaLTESARISDASSLKreegfsskslnsmdkqkesvslpsseekehwstkwrriawKC 335
Cdd:cd01116 205 ------------------------LEPKYPIKDKVLLL----------------------------------------KS 220
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 336 CVYL--VTIGMLVALLMGLNMSWTAVTAALALVVL-DFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLpsafwdFME 412
Cdd:cd01116 221 LTILtlVIIGFVLHSPLGVSLGWIALLGALLLLLLaDKLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGI------IEW 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 413 PHAQIDRVSG--TVVLALVILYLSNLAS----NVP-TVLLLGARVAASAAAISPMEEkrAWLLLAWISTVAGNLSLLGSA 485
Cdd:cd01116 295 IAELLVGVILgrIAVAVILILWISALLSafidNIPvTATMIPIVKDLASQLGIPLLP--LWWALALGACLGGNGTLIGAS 372
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 327187686 486 ANLIVCEQARRTpqlSYNLSFWNHLKFGVPSTLIVTAIGLV 526
Cdd:cd01116 373 ANVVAAGIAEQH---GYKISFWEFLKVGFPIMLVSLILATV 410
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
14-525 |
1.41e-17 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 85.01 E-value: 1.41e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 14 IAFATFWLLAVFPAI-PF-LPVGRTAgsLLGAMLMVVFRVLTPDQAYAAID--LPILGLLFGTMVVSVYLERADMFKYLG 89
Cdd:cd01118 1 LAIAIFVLTLVLVIWrPFgLPEAVWA--VLGAVIALILGLVSPHDALEVWGivWDVTLTLIGVILLSLLLDEEGFFEWVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 90 KVLSWRSKG-AKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNL---PPRPFLLALASSANIGSSATPIGNPQ 165
Cdd:cd01118 79 ALAARWARGsGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAkknRTLPFLYACAFIADAASLPLPISNLV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 166 NLVIAVQSKIPFGEF-VVGILPAMLVgvvvnaliILILYWKLLSVQKDeedpsseivadevVLSHRFSPARLshtqipsl 244
Cdd:cd01118 159 NIVTAGYFGIGFTEYaALMFLPSIVS--------ILATYVVLYLFFRR-------------ALPKRLETASV-------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 245 nspewesrldsmnanvetqrsvsskeneihrshsaltesarisdasslkreegfsskslnsmdkQKESVSLPSSeekehw 324
Cdd:cd01118 210 ----------------------------------------------------------------KKPSLAIKDP------ 219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 325 stKWRRIAWKCCVYLVTIGMLVALLMGLnmsWTAVTAALALVVL------DFKDAQPCLEKVSYSLLVFFCGMFMTVDGF 398
Cdd:cd01118 220 --LLFGLAWTLLVLLVVSAFGVDILLIP---PSFIAGVLALIFLllarrgGAINPLKVLKEAPWGVLLFSLGLYVVVFGL 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 399 NKTGLPSAFWDFMEPHAQIDRVSGTVVLALVILYLSNLASNVPTVLLLGARVAASAAaispmeekRAWLLLAWI--STVA 476
Cdd:cd01118 295 KNAGLTAILADLLNWLVSQGLLAAILGVGLLAAFLSNVMNNLPAVLIGALALAAGHA--------PEALVYANLigVDLG 366
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 327187686 477 GNLSLLGSAANLIVCEQARRTpqlSYNLSFWNHLKFG---VPSTLIVTAIGL 525
Cdd:cd01118 367 PKLTPIGSLATLLWLHVLRRK---GIRVSWGYYLKVGlivTPPVLVVTLAAL 415
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
14-206 |
5.00e-17 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 82.89 E-value: 5.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 14 IAFATFWLLAVFPAIPFLPVgrTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLS 93
Cdd:COG0471 179 AIFALTVLLWITGSLHGIPI--AVVALLGAVLLLLTGVLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 94 WRSKGAKD--LICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANiGSSATPIGNPQNLVIAV 171
Cdd:COG0471 257 PLLGGLSPllLLLLLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAAS-CAFLLPVGTPPNAIVYG 335
|
170 180 190
....*....|....*....|....*....|....*
gi 327187686 172 QSKIPFGEFVVGILPAMLVGVVVnALIILILYWKL 206
Cdd:COG0471 336 SGYYKFKDFLKVGLPLNLIGLVV-LLLLGPLWWPL 369
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
31-206 |
4.84e-15 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 76.85 E-value: 4.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 31 LPVGRTAgsLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLSWR-SKGAKDLICRVCLI 109
Cdd:cd01115 16 LPLDVTA--LLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRaGKGERRLLLLLMLV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 110 SAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNLVIAVQSKIPFGEFvVGILPAML 189
Cdd:cd01115 94 TAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQG-FSFFEFTP 172
|
170
....*....|....*..
gi 327187686 190 VGVVVNALIILILYWKL 206
Cdd:cd01115 173 IGLPLLIIGLLYLWFIF 189
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
2-204 |
1.64e-13 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 72.47 E-value: 1.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 2 AMDHTVKVILGSIAFATfwLLAVFPAIPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILgLLFGTMVVSVY-LE 80
Cdd:COG1055 211 AIKDRRLLRISLLVLAL--LLVGFVLHSFLGLPPALIALLGAAVLLLLARVDVREVLKKVDWSTL-LFFIGLFVVVGgLE 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 81 RADMFKYLGKVLSWRSKGAKDL-ICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPprPFLLALASSANIGSSAT 159
Cdd:COG1055 288 NTGLLDLLAELLASLTGGNLLLaALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPE--PLWLALALGATLGGNLT 365
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 327187686 160 PIGNPQNLVIAVQSK-----IPFGEFVVGILPAMLVGVVVNALIILILYW 204
Cdd:COG1055 366 PIGSAANVIVLGIAEkkgikISFGEFLKVGLPLTLLTLLIALLYLLLLYF 415
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
9-203 |
4.41e-13 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 70.69 E-value: 4.41e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 9 VILGSIAFATFWLLAVFPAIPFLPVGRTAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYL 88
Cdd:cd01115 187 FIFRLAVLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALI 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 89 GKVLSWRSKGAKD--LICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIgSSATPIGNPQN 166
Cdd:cd01115 267 AEALISLLGGLPPfaILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASC-AFMLPVGTPPN 345
|
170 180 190
....*....|....*....|....*....|....*..
gi 327187686 167 LVIAVQSKIPFGEFVVGILPAMLVGVVVNALIILILY 203
Cdd:cd01115 346 AIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
8-200 |
1.55e-11 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 66.12 E-value: 1.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 8 KVILGSIAFATFWLLAVFPAiPFLPVGRTAGSLLGAMLMVVF-RVLTPDQAYAAIDLPILgLLFGTMVVSVY-LERADMF 85
Cdd:cd01116 215 VLLLKSLTILTLVIIGFVLH-SPLGVSLGWIALLGALLLLLLaDKLDFEDVLSRVEWDTL-LFFAGLFVLVGgLEELGII 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 86 KYLGKVLSWRSKGakDLICRVCLI---SAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIG 162
Cdd:cd01116 293 EWIAELLVGVILG--RIAVAVILIlwiSALLSAFIDNIPVTATMIPIVKDLASQLGIPLLPLWWALALGACLGGNGTLIG 370
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 327187686 163 NPQNLVIAVQS-----KIPFGEFVVGILPAMLVGVVVNALIIL 200
Cdd:cd01116 371 ASANVVAAGIAeqhgyKISFWEFLKVGFPIMLVSLILATVYLL 413
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
70-528 |
3.07e-11 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 65.18 E-value: 3.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 70 FGTMVVSVYLERADMFKYLG-KVLSWRSKGAKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQ-----HNLPPRP 143
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIAlLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAlgsekRSKFGSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 144 FLLALASSANIGSSATPIGNPQNLVIA------VQSKIPFGEFVVGILPAMLVGVVvnaLIILILYWkLLSVQKDEEDPS 217
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAglleeaTGIPISFFEWMLVGLPVALVGLL---LLWLVLYR-LLPPEIKEVPGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 218 SEIVADEVvlshrfsparlshtqipslnspewesrldsmnanvetqrsvsskeneihrshsaltesarisdasslkreeg 297
Cdd:COG0471 157 KEVIREEL------------------------------------------------------------------------ 164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 298 fssKSLNSMDKQKesvslpsseekehwstkWRriawkccVYLVTIGMLVAL----LMGLNMSWTAVTAALALV---VLDF 370
Cdd:COG0471 165 ---AELGPLSRRE-----------------KI-------ALAIFALTVLLWitgsLHGIPIAVVALLGAVLLLltgVLTW 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 371 KDAQpclEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMEPHAQ-IDRVSGTVVLALVILYLSNLASNVPTVLLLG-- 447
Cdd:COG0471 218 KDAY---KSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLGgLSPLLLLLLLALLTLLLTEFASNTATAALLLpi 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 448 ARVAASAAAISPMeekrawlLLAWISTVAGNLSLL---GSAANLIVCEqarrtpqlSYNLSFWNHLKFGVPSTLIVTAIG 524
Cdd:COG0471 295 AISLAQALGVNPL-------PLALAVAFAASCAFLlpvGTPPNAIVYG--------SGYYKFKDFLKVGLPLNLIGLVVL 359
|
....
gi 327187686 525 LVLI 528
Cdd:COG0471 360 LLLG 363
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
10-199 |
4.83e-11 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 64.58 E-value: 4.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 10 ILGSIAFATFWLLAVFPAIPFLPVGrtAGSLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLG 89
Cdd:cd00625 208 FLLLALLLLLLFVLLFFFLIPLGLI--ALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 90 KVLSWRSK-GAKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIArqhnlPPRPFLLALASSANIGSSATPIGNPQNLV 168
Cdd:cd00625 286 ELLVALVGlPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLA-----PPEPAWLALALGSTLGGNLTLIGSLANLI 360
|
170 180 190
....*....|....*....|....*....|....*.
gi 327187686 169 IAVQS-----KIPFGEFVVGILPAMLVGVVVNALII 199
Cdd:cd00625 361 PLGAAenagvGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
14-149 |
4.81e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 45.38 E-value: 4.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 14 IAFATFWLLAVFPAIPFLPVGRTAgsLLGAMLMVVFRVLTPDQAYAAIDLPILGLLFGTMVVSVYLERADMFKYLGKVLS 93
Cdd:pfam03600 207 LLLAISALVLALVILGFLLLSVLA--LAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALG 284
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 327187686 94 WRSKGAKDLICrVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNL-PPRPFLLALA 149
Cdd:pfam03600 285 GLSGLLVALAL-ILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLgDPDPLAWALA 340
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
16-204 |
4.30e-04 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 42.72 E-value: 4.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 16 FATFW--LLAVFPAI--PFLPVGRTAGSLLGAMLMVVFRVLTPDQAYA-AIDLPILGLLFGTMVVSVYLERADMFKYLGK 90
Cdd:TIGR00785 249 KALLGifLLALLLWIfgGSLGINASVVALLAVVLMLFLGIVTWKDIQKnKVAWNTLILFGGLIGLAGGLKKSGFIKWFSE 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 91 VLSWRSKG---AKDLICRVCLISAISSAFFTNDTSCVVLTEFVLKIARQHNLPPRPFLLALASSANIGSSATPIGNPQNL 167
Cdd:TIGR00785 329 KLVGILDGlspTIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMGFLTPYATPPNA 408
|
170 180 190
....*....|....*....|....*....|....*..
gi 327187686 168 VIAVQSKIPFGEFVVGILPAMLVGVVVNALIIlILYW 204
Cdd:TIGR00785 409 IAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVG-TLWW 444
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
337-529 |
3.72e-03 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 39.73 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 337 VYLVTIGMLVALLMGLNMSWTAVTAALALV---VLDFKDAqpcLEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMep 413
Cdd:COG1055 8 IFVLTYLLIILEPRGLNRAVAALLGAALLLllgVVSLEDA---LEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKL-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 414 hAQIDRVSGTVVLALVILY---LSNLASNVPTVLLLGARVAASAAAispMEEKRAWLLLA--WISTVAGNLSLLGSAANL 488
Cdd:COG1055 83 -ARRAKGSPRRLLWLLGLLtalLSAFLDNDTTALLLTPVVLAIARR---LGLNPVPFLIAivFAANIGGAATPIGNPTNI 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 327187686 489 IVceqarrtpQLSYNLSFWNHLKFGVPSTLIVTAIGLVLIK 529
Cdd:COG1055 159 MI--------ASAGGLSFLDFLANLFPPSLVSLLVTLLVLY 191
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
344-528 |
6.74e-03 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 38.83 E-value: 6.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 344 MLVALLMGLNMSWTAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMEPHAQIDRVSGT 423
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 424 VVLALVILYLSNLASNVPTVLLLG--ARVAASAAAISPMeekRAWLLLAWISTVAGNLSLLGSAANLIVCEQARrtpqls 501
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIpiVLALARRLGLPPS---PLLIALAFAANIGGTATPIGDPPNIIIASALG------ 151
|
170 180
....*....|....*....|....*..
gi 327187686 502 ynLSFWNHLKFGVPSTLIVTAIGLVLI 528
Cdd:pfam03600 152 --LSFGDFGFFMFPPVGVALLLVGLLP 176
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
357-523 |
7.67e-03 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 38.72 E-value: 7.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 357 TAVTAALALVVLDFKDAQPCLEKVSYSLLVFFCGMFMTVDGFNKTGLPSAFWDFMEPHAQIDRVSGTVVLALVILYLSNL 436
Cdd:cd01115 21 TALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAF 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 327187686 437 ASNVPTVLLLgARVAASAAAISPMEEKRAWLLLAWISTVAGNLSLLGSAANLIVCEQARRTPqlSYNLSFWNHLKFGVPS 516
Cdd:cd01115 101 MSNTATVAIM-LPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVASGYLESLG--GQGFSFFEFTPIGLPL 177
|
....*..
gi 327187686 517 TLIVTAI 523
Cdd:cd01115 178 LIIGLLY 184
|
|
| |
