NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|194373529|dbj|BAG56860|]
View 

unnamed protein product [Homo sapiens]

Protein Classification

nucleotide-sugar transporter family protein( domain architecture ID 706892)

nucleotide-sugar transporter family protein may mediate the transport of nucleotides or sugars or their derivatives; belongs to the drug/metabolite transporter (DMT) superfamily

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
UAA super family cl26745
UAA transporter family; This family includes transporters with a specificity for ...
28-319 6.77e-66

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


The actual alignment was detected with superfamily member pfam08449:

Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 209.85  E-value: 6.77e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529   28 VSYLTWGVLQERVMTRSYGATatspGERFTDSQFLvlmnrvlALIVAGLSCVLCK-----QPRHGAPMYRYSFASLSNVL 102
Cdd:pfam08449  11 GGCCSNGVLQELIMKVEPGPF----GNLLTFAQFL-------FYALEGLPESIDIftskfLKPRKIPLKTYVILVALFFI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529  103 SSWCQYEALKF-VSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGPEP----RSSPATTLS 177
Cdd:pfam08449  80 TSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKvadsVVSPNFFLI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529  178 GLILLAGYIAFDSFTSNWQDALF-AYKMSSVQMMFGVNFFSCLFTvgsLLEQGALLEGTRFMGRHSEFAA--------HA 248
Cdd:pfam08449 160 GIAMLSGALLLDAFLGNYQEKTYkKYGKHSKEMLFYSHLLSLPFF---LLLQGDLFSAVQFCSQSPDKAVlslpsmlfYL 236
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194373529  249 VLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYAR 319
Cdd:pfam08449 237 LLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
28-319 6.77e-66

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 209.85  E-value: 6.77e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529   28 VSYLTWGVLQERVMTRSYGATatspGERFTDSQFLvlmnrvlALIVAGLSCVLCK-----QPRHGAPMYRYSFASLSNVL 102
Cdd:pfam08449  11 GGCCSNGVLQELIMKVEPGPF----GNLLTFAQFL-------FYALEGLPESIDIftskfLKPRKIPLKTYVILVALFFI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529  103 SSWCQYEALKF-VSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGPEP----RSSPATTLS 177
Cdd:pfam08449  80 TSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKvadsVVSPNFFLI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529  178 GLILLAGYIAFDSFTSNWQDALF-AYKMSSVQMMFGVNFFSCLFTvgsLLEQGALLEGTRFMGRHSEFAA--------HA 248
Cdd:pfam08449 160 GIAMLSGALLLDAFLGNYQEKTYkKYGKHSKEMLFYSHLLSLPFF---LLLQGDLFSAVQFCSQSPDKAVlslpsmlfYL 236
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194373529  249 VLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYAR 319
Cdd:pfam08449 237 LLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
28-319 6.77e-66

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 209.85  E-value: 6.77e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529   28 VSYLTWGVLQERVMTRSYGATatspGERFTDSQFLvlmnrvlALIVAGLSCVLCK-----QPRHGAPMYRYSFASLSNVL 102
Cdd:pfam08449  11 GGCCSNGVLQELIMKVEPGPF----GNLLTFAQFL-------FYALEGLPESIDIftskfLKPRKIPLKTYVILVALFFI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529  103 SSWCQYEALKF-VSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGPEP----RSSPATTLS 177
Cdd:pfam08449  80 TSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKvadsVVSPNFFLI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 194373529  178 GLILLAGYIAFDSFTSNWQDALF-AYKMSSVQMMFGVNFFSCLFTvgsLLEQGALLEGTRFMGRHSEFAA--------HA 248
Cdd:pfam08449 160 GIAMLSGALLLDAFLGNYQEKTYkKYGKHSKEMLFYSHLLSLPFF---LLLQGDLFSAVQFCSQSPDKAVlslpsmlfYL 236
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 194373529  249 VLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYAR 319
Cdd:pfam08449 237 LLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH