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Conserved domains on  [gi|37199524|dbj|BAC95355|]
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cell division protein BolA [Vibrio vulnificus YJ016]

Protein Classification

BolA family protein( domain architecture ID 10000955)

BolA family protein may be a stress-responsive transcriptional regulator and may also participate in iron metabolism; similar to mammalian BolA-like proteins that act as iron-sulfur (Fe-S) cluster assembly factors that facilitate [2Fe-2S] cluster insertion into a subset of cytosolic proteins, and to Haemophilus influenzae DNA-binding transcriptional regulator BolA

CATH:  3.30.300.90

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 24-110 5.11e-45

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


:

Pssm-ID: 440041  Cd Length: 90  Bit Score: 141.09  E-value: 5.11e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37199524  24 MIQEIIETKLHNTFEPSHLSVVNESYMHNVPPG--SESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHT 101
Cdd:COG0271   2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                ....*....
gi 37199524 102 YTDQEWKLQ 110
Cdd:COG0271  82 YTPEEWQAR 90
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 24-110 5.11e-45

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 141.09  E-value: 5.11e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37199524  24 MIQEIIETKLHNTFEPSHLSVVNESYMHNVPPG--SESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHT 101
Cdd:COG0271   2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                ....*....
gi 37199524 102 YTDQEWKLQ 110
Cdd:COG0271  82 YTPEEWQAR 90
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 23-123 1.86e-43

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 137.99  E-value: 1.86e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37199524   23 NMIQEIIETKLHNTFEPSHLSVVNESYMHNVPPGSESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHTY 102
Cdd:PRK11628   1 MMIREQIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTY 80

                         90       100
                 ....*....|....*....|.
gi 37199524  103 TDQEWKLQRDGAPDSPMCMGG 123
Cdd:PRK11628  81 TIKEWEGLQDTVFASPPCRGA 101
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 33-106 3.73e-37

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 121.02  E-value: 3.73e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37199524    33 LHNTFEPSHLSVVNESYMHNVPP-GSESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHTYTDQE 106
Cdd:pfam01722   1 LTEALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 24-110 5.11e-45

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 141.09  E-value: 5.11e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37199524  24 MIQEIIETKLHNTFEPSHLSVVNESYMHNVPPG--SESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHT 101
Cdd:COG0271   2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                ....*....
gi 37199524 102 YTDQEWKLQ 110
Cdd:COG0271  82 YTPEEWQAR 90
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 23-123 1.86e-43

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 137.99  E-value: 1.86e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37199524   23 NMIQEIIETKLHNTFEPSHLSVVNESYMHNVPPGSESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHTY 102
Cdd:PRK11628   1 MMIREQIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTY 80

                         90       100
                 ....*....|....*....|.
gi 37199524  103 TDQEWKLQRDGAPDSPMCMGG 123
Cdd:PRK11628  81 TIKEWEGLQDTVFASPPCRGA 101
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 33-106 3.73e-37

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 121.02  E-value: 3.73e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 37199524    33 LHNTFEPSHLSVVNESYMHNVPP-GSESHFKVIVVSDLFEGKRLIARHRLVNQALANELENNIHALAIHTYTDQE 106
Cdd:pfam01722   1 LTEALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
24-111 5.23e-22

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 82.50  E-value: 5.23e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 37199524  24 MIQEIIETKLHNTFEPSHLSVVnesymhnvppGSESHFKVIVVSDLFEGKRLIARHRLVNQALANELENN-IHALAIHTY 102
Cdd:COG5007   1 MTPEEIKQLIEAGLPCAEVEVE----------GDGSHFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIASGeIHALSIKTY 70


                ....*....
gi 37199524 103 TDQEWKLQR 111
Cdd:COG5007  71 TPEEWAAQR 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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