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Conserved domains on  [gi|12861554|dbj|BAB32226|]
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unnamed protein product [Mus musculus]

Protein Classification

LamG domain-containing protein( domain architecture ID 366259)

LamG (Laminin G) domain-containing protein may serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LamG super family cl22861
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ...
 1-99 5.31e-17

Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.


The actual alignment was detected with superfamily member smart00560:

Pssm-ID: 473984 [Multi-domain]  Cd Length: 133  Bit Score: 73.99  E-value: 5.31e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12861554      1 MFYYRTV--NGLQPPIKVMTPGRIlmKKWIHLTVQVHQTA--ISFFVDGLEENSTAFDTRtlhdSVTDSVSSVIQVGQSL 76
Cdd:smart00560  37 TFFLRAKsvQGWQTARTGATADWI--GVWVHLAGVYDGGAgkLSLYVNGVEVATSETQPS----PSSGNLPQGGRILLGG 110

                           90       100
                   ....*....|....*....|...
gi 12861554     77 NGSEQFVGRMQDFRLYNVSLTNR 99
Cdd:smart00560 111 AGGENFSGRLDEVRVYNRALTAR 133
 
Name Accession Description Interval E-value
LamGL smart00560
LamG-like jellyroll fold domain;
1-99 5.31e-17

LamG-like jellyroll fold domain;


Pssm-ID: 214722 [Multi-domain]  Cd Length: 133  Bit Score: 73.99  E-value: 5.31e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12861554      1 MFYYRTV--NGLQPPIKVMTPGRIlmKKWIHLTVQVHQTA--ISFFVDGLEENSTAFDTRtlhdSVTDSVSSVIQVGQSL 76
Cdd:smart00560  37 TFFLRAKsvQGWQTARTGATADWI--GVWVHLAGVYDGGAgkLSLYVNGVEVATSETQPS----PSSGNLPQGGRILLGG 110

                           90       100
                   ....*....|....*....|...
gi 12861554     77 NGSEQFVGRMQDFRLYNVSLTNR 99
Cdd:smart00560 111 AGGENFSGRLDEVRVYNRALTAR 133
Laminin_G_3 pfam13385
Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin ...
 26-101 3.75e-08

Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.


Pssm-ID: 463865 [Multi-domain]  Cd Length: 151  Bit Score: 50.85  E-value: 3.75e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 12861554    26 KWIHLTVQVHQTAISFFVDGleensTAFDTRTLHDSVTDSVSSVIQVGQSLNGSEQFVGRMQDFRLYNVSLTNREI 101
Cdd:pfam13385  80 QWTHVAVTYDGGTLRLYVNG-----VLVGSSTLTGGPPPGTGGPLYIGRSPGGDDYFNGLIDEVRIYDRALSAAEI 150
 
Name Accession Description Interval E-value
LamGL smart00560
LamG-like jellyroll fold domain;
1-99 5.31e-17

LamG-like jellyroll fold domain;


Pssm-ID: 214722 [Multi-domain]  Cd Length: 133  Bit Score: 73.99  E-value: 5.31e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12861554      1 MFYYRTV--NGLQPPIKVMTPGRIlmKKWIHLTVQVHQTA--ISFFVDGLEENSTAFDTRtlhdSVTDSVSSVIQVGQSL 76
Cdd:smart00560  37 TFFLRAKsvQGWQTARTGATADWI--GVWVHLAGVYDGGAgkLSLYVNGVEVATSETQPS----PSSGNLPQGGRILLGG 110

                           90       100
                   ....*....|....*....|...
gi 12861554     77 NGSEQFVGRMQDFRLYNVSLTNR 99
Cdd:smart00560 111 AGGENFSGRLDEVRVYNRALTAR 133
Laminin_G_3 pfam13385
Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin ...
 26-101 3.75e-08

Concanavalin A-like lectin/glucanases superfamily; This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.


Pssm-ID: 463865 [Multi-domain]  Cd Length: 151  Bit Score: 50.85  E-value: 3.75e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 12861554    26 KWIHLTVQVHQTAISFFVDGleensTAFDTRTLHDSVTDSVSSVIQVGQSLNGSEQFVGRMQDFRLYNVSLTNREI 101
Cdd:pfam13385  80 QWTHVAVTYDGGTLRLYVNG-----VLVGSSTLTGGPPPGTGGPLYIGRSPGGDDYFNGLIDEVRIYDRALSAAEI 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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