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Conserved domains on  [gi|12845021|dbj|BAB26588|]
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unnamed protein product, partial [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
eIF-3c_N super family cl20295
Eukaryotic translation initiation factor 3 subunit 8 N-terminus; The largest of the mammalian ...
 29-121 2.76e-44

Eukaryotic translation initiation factor 3 subunit 8 N-terminus; The largest of the mammalian translation initiation factors, eIF3, consists of at least eight subunits ranging in mass from 35 to 170 kDa. eIF3 binds to the 40 S ribosome in an early step of translation initiation and promotes the binding of methionyl-tRNAi and mRNA.


The actual alignment was detected with superfamily member pfam05470:

Pssm-ID: 428482  Cd Length: 593  Bit Score: 151.51  E-value: 2.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12845021    29 GNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIR 108
Cdd:pfam05470   1 KFLRDDSSDESSDEEDTKRVVKSAKDKRFEEMTSIIKTIRNAMKINDWVTLLEEFDLLNKAYQKAKTVQENVGTPRFYIK 80

                          90
                  ....*....|...
gi 12845021   109 ILADLEDYLNELW 121
Cdd:pfam05470  81 TLAELEDFLNELW 93
 
Name Accession Description Interval E-value
eIF-3c_N pfam05470
Eukaryotic translation initiation factor 3 subunit 8 N-terminus; The largest of the mammalian ...
 29-121 2.76e-44

Eukaryotic translation initiation factor 3 subunit 8 N-terminus; The largest of the mammalian translation initiation factors, eIF3, consists of at least eight subunits ranging in mass from 35 to 170 kDa. eIF3 binds to the 40 S ribosome in an early step of translation initiation and promotes the binding of methionyl-tRNAi and mRNA.


Pssm-ID: 428482  Cd Length: 593  Bit Score: 151.51  E-value: 2.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12845021    29 GNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIR 108
Cdd:pfam05470   1 KFLRDDSSDESSDEEDTKRVVKSAKDKRFEEMTSIIKTIRNAMKINDWVTLLEEFDLLNKAYQKAKTVQENVGTPRFYIK 80

                          90
                  ....*....|...
gi 12845021   109 ILADLEDYLNELW 121
Cdd:pfam05470  81 TLAELEDFLNELW 93
 
Name Accession Description Interval E-value
eIF-3c_N pfam05470
Eukaryotic translation initiation factor 3 subunit 8 N-terminus; The largest of the mammalian ...
 29-121 2.76e-44

Eukaryotic translation initiation factor 3 subunit 8 N-terminus; The largest of the mammalian translation initiation factors, eIF3, consists of at least eight subunits ranging in mass from 35 to 170 kDa. eIF3 binds to the 40 S ribosome in an early step of translation initiation and promotes the binding of methionyl-tRNAi and mRNA.


Pssm-ID: 428482  Cd Length: 593  Bit Score: 151.51  E-value: 2.76e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12845021    29 GNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNAMKIRDVTKCLEEFELLGKAYGKAKSIVDKEGVPRFYIR 108
Cdd:pfam05470   1 KFLRDDSSDESSDEEDTKRVVKSAKDKRFEEMTSIIKTIRNAMKINDWVTLLEEFDLLNKAYQKAKTVQENVGTPRFYIK 80

                          90
                  ....*....|...
gi 12845021   109 ILADLEDYLNELW 121
Cdd:pfam05470  81 TLAELEDFLNELW 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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