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Conserved domains on  [gi|2662299|dbj|BAA23739|]
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chitinase C [Streptomyces griseus]

Protein Classification

chitinase( domain architecture ID 10034482)

chitinase catalyzes the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. It belongs to the glycoside hydrolase family 19; GH19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Contains one or two C-terminal chitin-binding domains

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
chitinase_GH19 cd00325
Glycoside hydrolase family 19, chitinase domain; Chitinases are enzymes that catalyze the ...
 93-294 3.49e-85

Glycoside hydrolase family 19, chitinase domain; Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Glycoside hydrolase family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases, but they are smaller in size due to certain deletions. Despite lacking any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the prokaryotic/eukaryotic divergence.


:

Pssm-ID: 381595 [Multi-domain]  Cd Length: 224  Bit Score: 254.66  E-value: 3.49e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299   93 VSEAQFNQMFPNRNA----FYTYKGLTDALSAYPAFAKTGSDEVKKREAAAFLANVSHETG------------GLFYIKE 156
Cdd:cd00325   1 VTEDLFNELFPHRNDpakgFYTYDAFLAAAGSFPGFGNTGTDDIRKRELAAFLAHIAHETGggwaaaggpyawGLCYIEE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299  157 VNEANYPHYCDTTQsYGCPAGQAaYYGRGPIQLSWNFNYKAAGDALGI--NLLANPYLVEQDPAVAWKTGLWYWNSQNGP 234
Cdd:cd00325  81 IGCASDDCCSSSTG-YPCAPGKS-YYGRGPIQLSWNYNYGAASEALGGkdDLLNNPDLVATDPTLAFKTAIWFWMTPQGP 158

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2662299  235 GTMTPH------NAIVNNAGFGETIRSINGALECNGGNPAQVQSRINKFTQFTQILGTTTGPNLSC 294
Cdd:cd00325 159 KPSCHDvilsadRAAGRGPGFGATINIINGGLECGGGNNAQVQNRIGYYKRFCDILGVSPGDNLDC 224
ChtBD3 cd00036
Chitin/cellulose binding domains of chitinase and related enzymes; This group contains ...
 36-74 4.22e-15

Chitin/cellulose binding domains of chitinase and related enzymes; This group contains proteins related to the cellulose-binding domain of Erwinia chrysanthemi endoglucanase Z (EGZ) and Serratia marcescens chitinase B (ChiB). Gram negative plant parasite Erwinia chrysanthemi produces a variety of depolymerizing enzymes to metabolize pectin and cellulose on the host plant. Cellulase EGZ has a modular structure, with an N-terminal catalytic domain linked to a C-terminal cellulose-binding domain (CBD). CBD mediates the secretion activity of EGZ. Chitinases allow certain bacteria to utilize chitin as a energy source. Typically, non-plant chitinases are of the glycosidase family 18. Bacillus circulans Glycosidase ChiA1 hydrolyzes chitin and is comprised of several domains: the C-terminal chitin binding domain, an N-terminal catalytic domain, and 2 fibronectin type III-like domains. Bacillus circulans WL-12 ChiA1 facilitates invasion of fungal cell walls. The ChiA1 chitin binding domain is required for the specific recognition of insoluble chitin. although topologically and structurally related, ChiA1 lacks the characteristic aromatic residues of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)). Streptomyces griseus Chitinase C is a family 19 chitinase, and consists of a N-terminal chitin binding domain and a C-terminal chitin-catalytic domain that effects degradation. ChiC contains the characteristic chitin-binding aromatic residues. Chitinases function in invertebrates in the degradation of old exoskeletons, in fungi to utilize chitin in cell walls, and in bacteria which use chitin as an energy source.


:

Pssm-ID: 213175  Cd Length: 40  Bit Score: 67.79  E-value: 4.22e-15
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 2662299   36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNERPGTSDVWAD 74
Cdd:cd00036   2 WPNPTHYTAGQSVVYNGNLYTANWYTAGSVPGSDSSWTQ 40
 
Name Accession Description Interval E-value
chitinase_GH19 cd00325
Glycoside hydrolase family 19, chitinase domain; Chitinases are enzymes that catalyze the ...
 93-294 3.49e-85

Glycoside hydrolase family 19, chitinase domain; Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Glycoside hydrolase family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases, but they are smaller in size due to certain deletions. Despite lacking any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the prokaryotic/eukaryotic divergence.


Pssm-ID: 381595 [Multi-domain]  Cd Length: 224  Bit Score: 254.66  E-value: 3.49e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299   93 VSEAQFNQMFPNRNA----FYTYKGLTDALSAYPAFAKTGSDEVKKREAAAFLANVSHETG------------GLFYIKE 156
Cdd:cd00325   1 VTEDLFNELFPHRNDpakgFYTYDAFLAAAGSFPGFGNTGTDDIRKRELAAFLAHIAHETGggwaaaggpyawGLCYIEE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299  157 VNEANYPHYCDTTQsYGCPAGQAaYYGRGPIQLSWNFNYKAAGDALGI--NLLANPYLVEQDPAVAWKTGLWYWNSQNGP 234
Cdd:cd00325  81 IGCASDDCCSSSTG-YPCAPGKS-YYGRGPIQLSWNYNYGAASEALGGkdDLLNNPDLVATDPTLAFKTAIWFWMTPQGP 158

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2662299  235 GTMTPH------NAIVNNAGFGETIRSINGALECNGGNPAQVQSRINKFTQFTQILGTTTGPNLSC 294
Cdd:cd00325 159 KPSCHDvilsadRAAGRGPGFGATINIINGGLECGGGNNAQVQNRIGYYKRFCDILGVSPGDNLDC 224
GH19 COG3179
Chitinase, GH19 family [Carbohydrate transport and metabolism];
91-284 4.80e-54

Chitinase, GH19 family [Carbohydrate transport and metabolism];


Pssm-ID: 442412  Cd Length: 193  Bit Score: 174.34  E-value: 4.80e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299   91 FVVSEAQFNQMFPNRnAFYTYKGLTDAL-SAYPAFAKTgsdevKKREAAAFLANVSHETGGLFYIKEVNEAN-------- 161
Cdd:COG3179   2 FLITEAQLRAIFPGA-SFALAQGYAPALnAALPEFGIT-----TPLRLAHFLAQIAHESGGLRYLEENLNYSalqvfgry 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299  162 ---------YPHYCDTTQsYG--CPAGQAAYYGRGPIQLSWNFNYKAAGDALGINLLANPYLVEqDPAVAWKTGLWYWNS 230
Cdd:COG3179  76 pdgapeaiaNRVYGGRKD-LGntAPGDGWRYRGRGLIQLTGRANYRAAGDALGLDLVNNPDLLA-DPEVAARSAAWFWAT 153

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 2662299  231 QNgpgtmtpHNAIVNNAGFGETIRSINGALecNGgnpaqVQSRINKFTQFTQIL 284
Cdd:COG3179 154 RG-------LNALADAGDFGEVTRRINGGL--NG-----LDDRRARYQRAKAVL 193
Glyco_hydro_19 pfam00182
Chitinase class I;
92-294 2.54e-53

Chitinase class I;


Pssm-ID: 459702  Cd Length: 232  Bit Score: 173.88  E-value: 2.54e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299     92 VVSEAQFNQMFPNRN-------AFYTYKGLTDALSAYPAFAKTGSDEVKKREAAAFLANVSHET-------------GGL 151
Cdd:pfam00182   1 IVSRSLFDQMLKHRNddacpakGFYTYDAFIAAANSFPGFGTTGDDTARKKEIAAFFAQTSHETtggwatapdgpyaWGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299    152 FYIKEVNeaNYPHYCDTTQSYGCPAGQAaYYGRGPIQLSWNFNYKAAGDALGINLLANPYLVEQDPAVAWKTGLWYWNSQ 231
Cdd:pfam00182  81 CFVREQG--SPGDYCAPSAQWPCAPGKK-YYGRGPIQLSYNYNYGPAGQAIGQDLLNNPDLVATDAVVSFKTAIWFWMTP 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2662299    232 NGPGTmTPHNAIVNN-------------AGFGETIRSINGALECNGGNPAQVQSRINKFTQFTQILGTTTGPNLSC 294
Cdd:pfam00182 158 QSPKP-SCHDVITGQwtpsaadraanrvPGYGVITNIINGGLECGRGQNARVEDRIGFYRRYCGILGVPPGDNLDC 232
ChtBD3 cd00036
Chitin/cellulose binding domains of chitinase and related enzymes; This group contains ...
 36-74 4.22e-15

Chitin/cellulose binding domains of chitinase and related enzymes; This group contains proteins related to the cellulose-binding domain of Erwinia chrysanthemi endoglucanase Z (EGZ) and Serratia marcescens chitinase B (ChiB). Gram negative plant parasite Erwinia chrysanthemi produces a variety of depolymerizing enzymes to metabolize pectin and cellulose on the host plant. Cellulase EGZ has a modular structure, with an N-terminal catalytic domain linked to a C-terminal cellulose-binding domain (CBD). CBD mediates the secretion activity of EGZ. Chitinases allow certain bacteria to utilize chitin as a energy source. Typically, non-plant chitinases are of the glycosidase family 18. Bacillus circulans Glycosidase ChiA1 hydrolyzes chitin and is comprised of several domains: the C-terminal chitin binding domain, an N-terminal catalytic domain, and 2 fibronectin type III-like domains. Bacillus circulans WL-12 ChiA1 facilitates invasion of fungal cell walls. The ChiA1 chitin binding domain is required for the specific recognition of insoluble chitin. although topologically and structurally related, ChiA1 lacks the characteristic aromatic residues of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)). Streptomyces griseus Chitinase C is a family 19 chitinase, and consists of a N-terminal chitin binding domain and a C-terminal chitin-catalytic domain that effects degradation. ChiC contains the characteristic chitin-binding aromatic residues. Chitinases function in invertebrates in the degradation of old exoskeletons, in fungi to utilize chitin in cell walls, and in bacteria which use chitin as an energy source.


Pssm-ID: 213175  Cd Length: 40  Bit Score: 67.79  E-value: 4.22e-15
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 2662299   36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNERPGTSDVWAD 74
Cdd:cd00036   2 WPNPTHYTAGQSVVYNGNLYTANWYTAGSVPGSDSSWTQ 40
ChtBD3 smart00495
Chitin-binding domain type 3;
36-72 1.22e-10

Chitin-binding domain type 3;


Pssm-ID: 197760 [Multi-domain]  Cd Length: 41  Bit Score: 55.73  E-value: 1.22e-10
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2662299      36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNERPG-TSDVW 72
Cdd:smart00495   4 WQAGTVYTAGDVVSYNGKVYKAKWWTQGEEPGsSSGPW 41
CBM_5_12 pfam02839
Carbohydrate binding domain; This short domain is found in many different glycosyl hydrolase ...
 50-71 7.70e-03

Carbohydrate binding domain; This short domain is found in many different glycosyl hydrolase enzymes and is presumed to have a carbohydrate binding function. The domain has six aromatic groups that may be important for binding.


Pssm-ID: 427014  Cd Length: 25  Bit Score: 33.34  E-value: 7.70e-03
                          10        20
                  ....*....|....*....|..
gi 2662299     50 YNGRNYTAKWWTQNERPGTSDV 71
Cdd:pfam02839   1 HNGKAYQAKWWTQGGDPPTSSG 22
 
Name Accession Description Interval E-value
chitinase_GH19 cd00325
Glycoside hydrolase family 19, chitinase domain; Chitinases are enzymes that catalyze the ...
 93-294 3.49e-85

Glycoside hydrolase family 19, chitinase domain; Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Glycoside hydrolase family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases, but they are smaller in size due to certain deletions. Despite lacking any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the prokaryotic/eukaryotic divergence.


Pssm-ID: 381595 [Multi-domain]  Cd Length: 224  Bit Score: 254.66  E-value: 3.49e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299   93 VSEAQFNQMFPNRNA----FYTYKGLTDALSAYPAFAKTGSDEVKKREAAAFLANVSHETG------------GLFYIKE 156
Cdd:cd00325   1 VTEDLFNELFPHRNDpakgFYTYDAFLAAAGSFPGFGNTGTDDIRKRELAAFLAHIAHETGggwaaaggpyawGLCYIEE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299  157 VNEANYPHYCDTTQsYGCPAGQAaYYGRGPIQLSWNFNYKAAGDALGI--NLLANPYLVEQDPAVAWKTGLWYWNSQNGP 234
Cdd:cd00325  81 IGCASDDCCSSSTG-YPCAPGKS-YYGRGPIQLSWNYNYGAASEALGGkdDLLNNPDLVATDPTLAFKTAIWFWMTPQGP 158

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2662299  235 GTMTPH------NAIVNNAGFGETIRSINGALECNGGNPAQVQSRINKFTQFTQILGTTTGPNLSC 294
Cdd:cd00325 159 KPSCHDvilsadRAAGRGPGFGATINIINGGLECGGGNNAQVQNRIGYYKRFCDILGVSPGDNLDC 224
GH19 COG3179
Chitinase, GH19 family [Carbohydrate transport and metabolism];
91-284 4.80e-54

Chitinase, GH19 family [Carbohydrate transport and metabolism];


Pssm-ID: 442412  Cd Length: 193  Bit Score: 174.34  E-value: 4.80e-54
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299   91 FVVSEAQFNQMFPNRnAFYTYKGLTDAL-SAYPAFAKTgsdevKKREAAAFLANVSHETGGLFYIKEVNEAN-------- 161
Cdd:COG3179   2 FLITEAQLRAIFPGA-SFALAQGYAPALnAALPEFGIT-----TPLRLAHFLAQIAHESGGLRYLEENLNYSalqvfgry 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299  162 ---------YPHYCDTTQsYG--CPAGQAAYYGRGPIQLSWNFNYKAAGDALGINLLANPYLVEqDPAVAWKTGLWYWNS 230
Cdd:COG3179  76 pdgapeaiaNRVYGGRKD-LGntAPGDGWRYRGRGLIQLTGRANYRAAGDALGLDLVNNPDLLA-DPEVAARSAAWFWAT 153

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....
gi 2662299  231 QNgpgtmtpHNAIVNNAGFGETIRSINGALecNGgnpaqVQSRINKFTQFTQIL 284
Cdd:COG3179 154 RG-------LNALADAGDFGEVTRRINGGL--NG-----LDDRRARYQRAKAVL 193
Glyco_hydro_19 pfam00182
Chitinase class I;
92-294 2.54e-53

Chitinase class I;


Pssm-ID: 459702  Cd Length: 232  Bit Score: 173.88  E-value: 2.54e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299     92 VVSEAQFNQMFPNRN-------AFYTYKGLTDALSAYPAFAKTGSDEVKKREAAAFLANVSHET-------------GGL 151
Cdd:pfam00182   1 IVSRSLFDQMLKHRNddacpakGFYTYDAFIAAANSFPGFGTTGDDTARKKEIAAFFAQTSHETtggwatapdgpyaWGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2662299    152 FYIKEVNeaNYPHYCDTTQSYGCPAGQAaYYGRGPIQLSWNFNYKAAGDALGINLLANPYLVEQDPAVAWKTGLWYWNSQ 231
Cdd:pfam00182  81 CFVREQG--SPGDYCAPSAQWPCAPGKK-YYGRGPIQLSYNYNYGPAGQAIGQDLLNNPDLVATDAVVSFKTAIWFWMTP 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2662299    232 NGPGTmTPHNAIVNN-------------AGFGETIRSINGALECNGGNPAQVQSRINKFTQFTQILGTTTGPNLSC 294
Cdd:pfam00182 158 QSPKP-SCHDVITGQwtpsaadraanrvPGYGVITNIINGGLECGRGQNARVEDRIGFYRRYCGILGVPPGDNLDC 232
ChtBD3 cd00036
Chitin/cellulose binding domains of chitinase and related enzymes; This group contains ...
 36-74 4.22e-15

Chitin/cellulose binding domains of chitinase and related enzymes; This group contains proteins related to the cellulose-binding domain of Erwinia chrysanthemi endoglucanase Z (EGZ) and Serratia marcescens chitinase B (ChiB). Gram negative plant parasite Erwinia chrysanthemi produces a variety of depolymerizing enzymes to metabolize pectin and cellulose on the host plant. Cellulase EGZ has a modular structure, with an N-terminal catalytic domain linked to a C-terminal cellulose-binding domain (CBD). CBD mediates the secretion activity of EGZ. Chitinases allow certain bacteria to utilize chitin as a energy source. Typically, non-plant chitinases are of the glycosidase family 18. Bacillus circulans Glycosidase ChiA1 hydrolyzes chitin and is comprised of several domains: the C-terminal chitin binding domain, an N-terminal catalytic domain, and 2 fibronectin type III-like domains. Bacillus circulans WL-12 ChiA1 facilitates invasion of fungal cell walls. The ChiA1 chitin binding domain is required for the specific recognition of insoluble chitin. although topologically and structurally related, ChiA1 lacks the characteristic aromatic residues of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)). Streptomyces griseus Chitinase C is a family 19 chitinase, and consists of a N-terminal chitin binding domain and a C-terminal chitin-catalytic domain that effects degradation. ChiC contains the characteristic chitin-binding aromatic residues. Chitinases function in invertebrates in the degradation of old exoskeletons, in fungi to utilize chitin in cell walls, and in bacteria which use chitin as an energy source.


Pssm-ID: 213175  Cd Length: 40  Bit Score: 67.79  E-value: 4.22e-15
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 2662299   36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNERPGTSDVWAD 74
Cdd:cd00036   2 WPNPTHYTAGQSVVYNGNLYTANWYTAGSVPGSDSSWTQ 40
ChiC_BD cd12215
Chitin-binding domain of chitinase C; Chitin-binding domain of chitinase C (ChiC) of ...
 36-74 2.43e-14

Chitin-binding domain of chitinase C; Chitin-binding domain of chitinase C (ChiC) of Streptomyces griseus and related proteins. Chitinase C is a family 19 chitinase, and consists of a N-terminal chitin binding domain and a C-terminal chitin-catalytic domain that effects degradation. Chitinases function in invertebrates in the degradation of old exoskeletons, in fungi to utilize chitin in cell walls, and in bacteria which use chitin as an energy source. ChiC contains the characteristic chitin-binding aromatic residues.


Pssm-ID: 213178 [Multi-domain]  Cd Length: 42  Bit Score: 65.67  E-value: 2.43e-14
                        10        20        30        40
                ....*....|....*....|....*....|....*....|
gi 2662299   36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNERPGTS-DVWAD 74
Cdd:cd12215   3 WDASTVYTGGDQVTYNGKVYEAKWWTQGEEPGTSwGVWKL 42
ChtBD3 smart00495
Chitin-binding domain type 3;
36-72 1.22e-10

Chitin-binding domain type 3;


Pssm-ID: 197760 [Multi-domain]  Cd Length: 41  Bit Score: 55.73  E-value: 1.22e-10
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2662299      36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNERPG-TSDVW 72
Cdd:smart00495   4 WQAGTVYTAGDVVSYNGKVYKAKWWTQGEEPGsSSGPW 41
CBD_like cd12204
Cellulose-binding domain, chitinase and related proteins; This group contains proteins related ...
 36-73 5.14e-06

Cellulose-binding domain, chitinase and related proteins; This group contains proteins related to the cellulose-binding domain of Erwinia chrysanthemi endoglucanase Z (EGZ) and Serratia marcescens chitinase B (ChiB). Gram negative plant parasite Erwinia chrysanthemi produces a variety of depolymerizing enzymes to metabolize pectin and cellulose on the host plant. Cellulase EGZ has a modular structure, with N-terminal catalytic domain linked to a C-terminal cellulose-binding domain (CBD). CBD mediates the secretion activity of EGZ. Chitinases allow certain bacteria to utilize chitin as a energy source. Typically, non-plant chitinases are of the glycosidase family 18.


Pssm-ID: 213176  Cd Length: 48  Bit Score: 42.70  E-value: 5.14e-06
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 2662299   36 WSSSSVYTNGGTVSYNGRNYTAKWWTQNErPGTSDVWA 73
Cdd:cd12204   9 WPQGTHAAGGDLVSYNGAVYQAKWWTQSA-PGSDSSWT 45
CBM_5_12 pfam02839
Carbohydrate binding domain; This short domain is found in many different glycosyl hydrolase ...
 50-71 7.70e-03

Carbohydrate binding domain; This short domain is found in many different glycosyl hydrolase enzymes and is presumed to have a carbohydrate binding function. The domain has six aromatic groups that may be important for binding.


Pssm-ID: 427014  Cd Length: 25  Bit Score: 33.34  E-value: 7.70e-03
                          10        20
                  ....*....|....*....|..
gi 2662299     50 YNGRNYTAKWWTQNERPGTSDV 71
Cdd:pfam02839   1 HNGKAYQAKWWTQGGDPPTSSG 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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