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Conserved domains on  [gi|334351032|sp|B2WB15|]
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RecName: Full=Restriction of telomere capping protein 5

Protein Classification

TLD domain-containing protein( domain architecture ID 10554278)

TLD domain-containing protein similar to fungal restriction of telomere capping protein 5 (RTC5) and oxidation resistance protein 1 (OXR1) that may be involved in a process influencing telomere capping and in protection from oxidative damage, respectively

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TLD pfam07534
TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It ...
 362-569 3.94e-26

TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.


:

Pssm-ID: 429519  Cd Length: 139  Bit Score: 103.84  E-value: 3.94e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032  362 LYSGNTHGFSMGSFEKQVfNWRAPTILLVKgrllpttpsttreralqdmlppkrhpssitpdslsSNQTLIYGAYISSQW 441
Cdd:pfam07534   2 LYSTSRDGSSYQTFLEKI-DNKGPTLLIIK-----------------------------------DNDGYIFGAFASQPW 45

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032  442 KHTGKTCFGDASTTLFQLSPTHDVFTASAFSHDYTYFSKSpttpaGLGLGTPIPtqsashsshshshshpvfrpgPVSLH 521
Cdd:pfam07534  46 KVSGKKFYGDGESFLFSLSPQFDPYKWTGKNNAYFNCTSD-----GLGFGGGQP---------------------KFDLW 99

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 334351032  522 LDDALEFAVFTHlaegGGSFLPSKLParkgSDWQDRFEIESLEVWGCG 569
Cdd:pfam07534 100 IDSDLEFGYSRH----CETFGNGQLS----GSGQERFKIDDVEVWGLG 139
DUF1773 pfam08593
Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene ...
 293-352 1.10e-13

Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene products from fission yeast. The actual function is not yet known but the proteins are likely to be cell-surface glycoproteins.


:

Pssm-ID: 400766  Cd Length: 58  Bit Score: 65.83  E-value: 1.10e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334351032  293 HFLFAKDMDLSKRKGGPNSPTKESKPVIPPPKaqsePILREPGEILNLTILS--QLSFFLKG 352
Cdd:pfam08593   1 HFLFSKNENFSKRKNGYPASPVPFLNGEEPED----YELPPIGSIEDIDNLSkeQCSFYLPG 58
 
Name Accession Description Interval E-value
TLD pfam07534
TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It ...
 362-569 3.94e-26

TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.


Pssm-ID: 429519  Cd Length: 139  Bit Score: 103.84  E-value: 3.94e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032  362 LYSGNTHGFSMGSFEKQVfNWRAPTILLVKgrllpttpsttreralqdmlppkrhpssitpdslsSNQTLIYGAYISSQW 441
Cdd:pfam07534   2 LYSTSRDGSSYQTFLEKI-DNKGPTLLIIK-----------------------------------DNDGYIFGAFASQPW 45

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032  442 KHTGKTCFGDASTTLFQLSPTHDVFTASAFSHDYTYFSKSpttpaGLGLGTPIPtqsashsshshshshpvfrpgPVSLH 521
Cdd:pfam07534  46 KVSGKKFYGDGESFLFSLSPQFDPYKWTGKNNAYFNCTSD-----GLGFGGGQP---------------------KFDLW 99

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 334351032  522 LDDALEFAVFTHlaegGGSFLPSKLParkgSDWQDRFEIESLEVWGCG 569
Cdd:pfam07534 100 IDSDLEFGYSRH----CETFGNGQLS----GSGQERFKIDDVEVWGLG 139
TLDc smart00584
domain in TBC and LysM domain containing proteins;
336-569 2.37e-17

domain in TBC and LysM domain containing proteins;


Pssm-ID: 214733  Cd Length: 165  Bit Score: 79.67  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032   336 EILNLTILSQLSFFLKGSDLFRRLRPLYSGNTHGFSMGSFEKQVFNWRAPTILLVKgrllpttpsTTRERalqdmlppkr 415
Cdd:smart00584   2 SILSEEILALINSHLPTRAEGYPWTLLYSSSQHGYSLNTLYRKVEGYRPPTLLIIK---------DTDGE---------- 62

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032   416 hpssitpdslssnqtlIYGAYISSQWKHTGKTcFGDASTTLFQLSPTHDVFTASAFSHDYTYFSKSPTTPAGLGLGTPip 495
Cdd:smart00584  63 ----------------VFGAYASQAWRVSDHF-YGTGESFLFQLNPKFVVYDWTGKNKYYYINGTPDSLPIGGGGGGF-- 123

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334351032   496 tqsashsshshshshpvfrpgpvSLHLDDALEFAVFTHLAEGGGSFLPSKlparkgsdwQDRFEIESLEVWGCG 569
Cdd:smart00584 124 -----------------------GLWIDEDLNHGSSSHCKTFGNPPLSTK---------QEDFLILDIEVWGFG 165
DUF1773 pfam08593
Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene ...
 293-352 1.10e-13

Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene products from fission yeast. The actual function is not yet known but the proteins are likely to be cell-surface glycoproteins.


Pssm-ID: 400766  Cd Length: 58  Bit Score: 65.83  E-value: 1.10e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334351032  293 HFLFAKDMDLSKRKGGPNSPTKESKPVIPPPKaqsePILREPGEILNLTILS--QLSFFLKG 352
Cdd:pfam08593   1 HFLFSKNENFSKRKNGYPASPVPFLNGEEPED----YELPPIGSIEDIDNLSkeQCSFYLPG 58
 
Name Accession Description Interval E-value
TLD pfam07534
TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It ...
 362-569 3.94e-26

TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.


Pssm-ID: 429519  Cd Length: 139  Bit Score: 103.84  E-value: 3.94e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032  362 LYSGNTHGFSMGSFEKQVfNWRAPTILLVKgrllpttpsttreralqdmlppkrhpssitpdslsSNQTLIYGAYISSQW 441
Cdd:pfam07534   2 LYSTSRDGSSYQTFLEKI-DNKGPTLLIIK-----------------------------------DNDGYIFGAFASQPW 45

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032  442 KHTGKTCFGDASTTLFQLSPTHDVFTASAFSHDYTYFSKSpttpaGLGLGTPIPtqsashsshshshshpvfrpgPVSLH 521
Cdd:pfam07534  46 KVSGKKFYGDGESFLFSLSPQFDPYKWTGKNNAYFNCTSD-----GLGFGGGQP---------------------KFDLW 99

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 334351032  522 LDDALEFAVFTHlaegGGSFLPSKLParkgSDWQDRFEIESLEVWGCG 569
Cdd:pfam07534 100 IDSDLEFGYSRH----CETFGNGQLS----GSGQERFKIDDVEVWGLG 139
TLDc smart00584
domain in TBC and LysM domain containing proteins;
336-569 2.37e-17

domain in TBC and LysM domain containing proteins;


Pssm-ID: 214733  Cd Length: 165  Bit Score: 79.67  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032   336 EILNLTILSQLSFFLKGSDLFRRLRPLYSGNTHGFSMGSFEKQVFNWRAPTILLVKgrllpttpsTTRERalqdmlppkr 415
Cdd:smart00584   2 SILSEEILALINSHLPTRAEGYPWTLLYSSSQHGYSLNTLYRKVEGYRPPTLLIIK---------DTDGE---------- 62

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334351032   416 hpssitpdslssnqtlIYGAYISSQWKHTGKTcFGDASTTLFQLSPTHDVFTASAFSHDYTYFSKSPTTPAGLGLGTPip 495
Cdd:smart00584  63 ----------------VFGAYASQAWRVSDHF-YGTGESFLFQLNPKFVVYDWTGKNKYYYINGTPDSLPIGGGGGGF-- 123

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334351032   496 tqsashsshshshshpvfrpgpvSLHLDDALEFAVFTHLAEGGGSFLPSKlparkgsdwQDRFEIESLEVWGCG 569
Cdd:smart00584 124 -----------------------GLWIDEDLNHGSSSHCKTFGNPPLSTK---------QEDFLILDIEVWGFG 165
DUF1773 pfam08593
Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene ...
 293-352 1.10e-13

Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene products from fission yeast. The actual function is not yet known but the proteins are likely to be cell-surface glycoproteins.


Pssm-ID: 400766  Cd Length: 58  Bit Score: 65.83  E-value: 1.10e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334351032  293 HFLFAKDMDLSKRKGGPNSPTKESKPVIPPPKaqsePILREPGEILNLTILS--QLSFFLKG 352
Cdd:pfam08593   1 HFLFSKNENFSKRKNGYPASPVPFLNGEEPED----YELPPIGSIEDIDNLSkeQCSFYLPG 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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