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Conserved domains on  [gi|1447648657|gb|AXM91199|]
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ABC transporter ATP-binding protein [Bifidobacterium bifidum]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
P-loop_NTPase super family cl38936
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ...
 3-198 2.73e-52

P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families.


The actual alignment was detected with superfamily member cd03255:

Pssm-ID: 476819 [Multi-domain]  Cd Length: 218  Bit Score: 166.90  E-value: 2.73e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW--------- 70
Cdd:cd03255     1 IELKNLSKTYGGGGEKVQalkGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLsekelaafr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ------IFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:cd03255    81 rrhigfVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03255   161 IILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVV-THDPELAEYADRIIELRD 215
 
Name Accession Description Interval E-value
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 3-198 2.73e-52

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 166.90  E-value: 2.73e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW--------- 70
Cdd:cd03255     1 IELKNLSKTYGGGGEKVQalkGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLsekelaafr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ------IFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:cd03255    81 rrhigfVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03255   161 IILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVV-THDPELAEYADRIIELRD 215
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
3-198 2.77e-52

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 167.14  E-value: 2.77e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----------SMR 69
Cdd:COG1136     5 LELRNLTKSYGTGEGEVTalrGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDisslserelaRLR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 -----WIFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:COG1136    85 rrhigFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:COG1136   165 LILADEPTGNLDSKTGEEVLELLRELNRELgtTIVMV-THDPELAARADRVIRLRD 219
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 3-184 7.43e-40

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 135.07  E-value: 7.43e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW------------ 70
Cdd:TIGR02673   2 IEFHNVSKAYPGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLrgrqlpllrrri 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 --IFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTrvtDRRFA---ELSGGEAQRLMLARAFAAQPSL 145
Cdd:TIGR02673  82 gvVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLE---HKADAfpeQLSGGEQQRVAIARAIVNSPPL 158

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDP 184
Cdd:TIGR02673 159 LLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDL 197
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-153 4.53e-37

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 125.84  E-value: 4.53e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDS-----------MRWIFQNPHGVAQRTAIDHV 87
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLtdderkslrkeIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 SLPLLAKGLPRREAEEQARTLMDRFNLT----RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGdladRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
11-196 2.03e-33

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 117.72  E-value: 2.03e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSmrwifqnPHGVAQRTAIDHvSLP 90
Cdd:NF040873    1 GYGGRPVL-HGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGAR-------VAYVPQRSEVPD-SLP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKGL--------------PRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:NF040873   72 LTVRDLvamgrwarrglwrrLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 157 MHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDIIDL 196
Cdd:NF040873  152 AESRERIIALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
11-183 3.44e-33

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 118.76  E-value: 3.44e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYADGPLL---FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSMR-------------WIF 72
Cdd:PRK11629   14 RYQEGSVQtdvLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGqpMSKLSsaakaelrnqklgFIY 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 QNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:PRK11629   94 QFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPT 173

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1447648657 153 AQLDMHTAATVSESLSRI-ARNDTIVVVSTHD 183
Cdd:PRK11629  174 GNLDARNADSIFQLLGELnRLQGTAFLVVTHD 205
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
96-182 5.41e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 60.52  E-value: 5.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  96 LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDT 175
Cdd:NF000106  116 LSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGA 195


                  ....*..
gi 1447648657 176 IVVVSTH 182
Cdd:NF000106  196 TVLLTTQ 202
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-152 7.68e-10

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 57.44  E-value: 7.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwifqnphgVAQRT 82
Cdd:NF033858    2 ARLEGVSHRYGKTVAL-DDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGD-----------MADAR 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVS-----LPL-LAK-------------------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLAR 137
Cdd:NF033858   70 HRRAVCpriayMPQgLGKnlyptlsvfenldffgrlfGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCC 149

                         170
                  ....*....|....*
gi 1447648657 138 AFAAQPSLMLVDEPT 152
Cdd:NF033858  150 ALIHDPDLLILDEPT 164
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-188 7.95e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.07  E-value: 7.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVtrqgidsmrwIFQNPhgvaqrtaidhvslpllakglprreaeEQART 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV----------IYIDG---------------------------EDILE 43

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  108 LMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES------LSRIARNDTIVVVST 181
Cdd:smart00382  44 EVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrllLLLKSEKNLTVILTT 123


                   ....*..
gi 1447648657  182 HDPNTRD 188
Cdd:smart00382 124 NDEKDLG 130
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
95-182 9.12e-07

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 48.58  E-value: 9.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDmhtaaTVS-----ESLSR 169
Cdd:NF033858  368 HLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD-----PVArdmfwRLLIE 442

                          90
                  ....*....|....*
gi 1447648657 170 IARND--TIvVVSTH 182
Cdd:NF033858  443 LSREDgvTI-FISTH 456
 
Name Accession Description Interval E-value
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 3-198 2.73e-52

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 166.90  E-value: 2.73e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW--------- 70
Cdd:cd03255     1 IELKNLSKTYGGGGEKVQalkGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLsekelaafr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ------IFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:cd03255    81 rrhigfVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03255   161 IILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVV-THDPELAEYADRIIELRD 215
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
3-198 2.77e-52

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 167.14  E-value: 2.77e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----------SMR 69
Cdd:COG1136     5 LELRNLTKSYGTGEGEVTalrGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDisslserelaRLR 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 -----WIFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:COG1136    85 rrhigFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRPK 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:COG1136   165 LILADEPTGNLDSKTGEEVLELLRELNRELgtTIVMV-THDPELAARADRVIRLRD 219
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 3-183 1.99e-45

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 149.54  E-value: 1.99e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGP---LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTR-----QGIDSMR-WIFQ 73
Cdd:cd03293     1 LEVRNVSKTYGGGGgavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVdgepvTGPGPDRgYVFQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:cd03293    81 QDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFS 160

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1447648657 154 QLDMHTAATVSESLSRIARND--TIVVVsTHD 183
Cdd:cd03293   161 ALDALTREQLQEELLDIWRETgkTVLLV-THD 191
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-183 2.77e-44

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 147.93  E-value: 2.77e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRY--ADGPLL-FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------SMRWI 71
Cdd:COG1116     6 PALELRGVSKRFptGGGGVTaLDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPvtgpgpDRGVV 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEP 151
Cdd:COG1116    86 FQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEP 165

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 152 TAQLDMHTAATVSESLSRIARND--TIVVVsTHD 183
Cdd:COG1116   166 FGALDALTRERLQDELLRLWQETgkTVLFV-THD 198
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 3-185 5.34e-43

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 143.63  E-value: 5.34e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW-----------I 71
Cdd:COG1122     1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKnlrelrrkvglV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHgvAQ---RTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:COG1122    81 FQNPD--DQlfaPTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVL 158

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPN 185
Cdd:COG1122   159 DEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLD 195
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
3-185 1.07e-42

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 142.50  E-value: 1.07e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID--SMRW---------- 70
Cdd:COG2884     2 IRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDlsRLKRreipylrrri 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 --IFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:COG2884    82 gvVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLA 161

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPN 185
Cdd:COG2884   162 DEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLE 198
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 3-194 2.90e-42

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 142.15  E-value: 2.90e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNPHGVA--- 79
Cdd:COG1121     7 IELENLTVSYGGRPVL-EDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKP----PRRARRRIGyvp 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 QRTAIDH---------VSLPLLAK----GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG1121    82 QRAEVDWdfpitvrdvVLMGRYGRrglfRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQDPDLL 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNT-RDACTDII 194
Cdd:COG1121   162 LLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAvREYFDRVL 210
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
3-183 1.48e-41

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 140.20  E-value: 1.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR----------WIF 72
Cdd:COG1131     1 IEVRGLTKRYGDKTAL-DGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARdpaevrrrigYVP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 QNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:COG1131    80 QEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEPT 159

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1447648657 153 AQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:COG1131   160 SGLDPEARRELWELLRELAAEGKTVLLSTHY 190
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 1-199 2.10e-41

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 138.77  E-value: 2.10e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYaDGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----------SMRW 70
Cdd:COG4133     1 MMLEAENLSCRR-GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPirdaredyrrRLAY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHGVAQRTAIDHVSLplLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:COG4133    80 LGHADGLKPELTVRENLRF--WAALYGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDE 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 151 PTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACtDIIDLKNY 199
Cdd:COG4133   158 PFTALDAAGVALLAELIAAHLARGGAVLLTTHQPLELAAA-RVLDLGDF 205
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 3-190 8.01e-41

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 138.34  E-value: 8.01e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRY--ADGPL-LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------------- 66
Cdd:COG4181     9 IELRGLTKTVgtGAGELtILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDlfaldedararlr 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  67 --SMRWIFQNPHGVAQRTAIDHVSLPLLAKGlpRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:COG4181    89 arHVGFVFQSFQLLPTLTALENVMLPLELAG--RRDARARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEPA 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVsTHDPNTRDAC 190
Cdd:COG4181   167 ILFADEPTGNLDAATGEQIIDLLFELNRERgtTLVLV-THDPALAARC 213
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 5-198 2.63e-40

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 137.30  E-value: 2.63e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR----------WIFQN 74
Cdd:COG4555     4 VENLSKKYGKVPAL-KDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKeprearrqigVLPDE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  75 PHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:COG4555    83 RGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNG 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 155 LDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDA-CTDIIDLKN 198
Cdd:COG4555   163 LDVMARRLLREILRALKKEGKTVLFSSHIMQEVEAlCDRVVILHK 207
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 3-185 3.52e-40

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 136.11  E-value: 3.52e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW---------IFQ 73
Cdd:cd03259     1 LELKGLSKTYGSVRAL-DDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVpperrnigmVFQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 N----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:cd03259    80 DyalfPH----LTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLD 155

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 150 EPTAQLDMHTAATVSESLSRIARN-DTIVVVSTHDPN 185
Cdd:cd03259   156 EPLSALDAKLREELREELKELQRElGITTIYVTHDQE 192
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 3-198 6.45e-40

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 142.59  E-value: 6.45e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMRWI 71
Cdd:COG4988   337 IELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDlsdldpaswrrQIAWV 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPH----------GVAQRTAIDHvslpLLAKGLPRREAEEQARTLMDRFNlTRVTDRRFAeLSGGEAQRLMLARAFAA 141
Cdd:COG4988   417 PQNPYlfagtirenlRLGRPDASDE----ELEAALEAAGLDEFVAALPDGLD-TPLGEGGRG-LSGGQAQRLALARALLR 490

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1447648657 142 QPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:COG4988   491 DAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILI-THRLALLAQADRILVLDD 546
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 3-184 7.43e-40

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 135.07  E-value: 7.43e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW------------ 70
Cdd:TIGR02673   2 IEFHNVSKAYPGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLrgrqlpllrrri 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 --IFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTrvtDRRFA---ELSGGEAQRLMLARAFAAQPSL 145
Cdd:TIGR02673  82 gvVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLE---HKADAfpeQLSGGEQQRVAIARAIVNSPPL 158

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDP 184
Cdd:TIGR02673 159 LLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDL 197
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 5-185 1.99e-39

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 133.75  E-value: 1.99e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADG-PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW-----------IF 72
Cdd:cd03225     2 LKNLSFSYPDGaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLslkelrrkvglVF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 QNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEP 151
Cdd:cd03225    82 QNPdDQFFGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEP 161

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 152 TAQLDMHTAATVSESLSRIARNDTIVVVSTHDPN 185
Cdd:cd03225   162 TAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLD 195
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 2-185 1.57e-38

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 132.86  E-value: 1.57e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSMR---------W 70
Cdd:COG1120     1 MLEAENLSVGYGGRPVL-DDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGrdLASLSrrelarriaY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHGVAQRTAIDHVSL---PLL-AKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG1120    80 VPQEPPAPFGLTVRELVALgryPHLgLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLL 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIARN-DTIVVVSTHDPN 185
Cdd:COG1120   160 LLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLN 199
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 4-198 1.64e-38

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 130.63  E-value: 1.64e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   4 DLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQRTA 83
Cdd:cd03214     1 EVENLSVGYGGRTVL-DDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASL---SPKELARKIA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  84 IdhvslpllakgLPrreaeeQArtlMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATV 163
Cdd:cd03214    77 Y-----------VP------QA---LELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIEL 136

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 164 SESLSRIAR-NDTIVVVSTHDPN-TRDACTDIIDLKN 198
Cdd:cd03214   137 LELLRRLAReRGKTVVMVLHDLNlAARYADRVILLKD 173
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
5-200 1.46e-37

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 129.17  E-value: 1.46e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-----RQGIDSMRW------IFQ 73
Cdd:COG4619     3 LEGLSFRVGGKPIL-SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYldgkpLSAMPPPEWrrqvayVPQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPHGVAQrTAIDHVSLPLLAKGlpRREAEEQARTLMDRFNLT-RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:COG4619    82 EPALWGG-TVRDNLPFPFQLRE--RKFDRERALELLERLGLPpDILDKPVERLSGGERQRLALIRALLLQPDVLLLDEPT 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 153 AQLDMHTAATVSESLSRIARND--TIVVVsTHDPN-TRDACTDIIDLKNYQ 200
Cdd:COG4619   159 SALDPENTRRVEELLREYLAEEgrAVLWV-SHDPEqIERVADRVLTLEAGR 208
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-153 4.53e-37

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 125.84  E-value: 4.53e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDS-----------MRWIFQNPHGVAQRTAIDHV 87
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLtdderkslrkeIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 SLPLLAKGLPRREAEEQARTLMDRFNLT----RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGdladRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 5-200 1.08e-36

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 125.43  E-value: 1.08e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFqnphgvaqRTAI 84
Cdd:cd00267     2 IENLSFRYGGRTAL-DNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPL--------EELR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHVSLpllakgLPrreaeeqartlmdrfnltrvtdrrfaELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVS 164
Cdd:cd00267    73 RRIGY------VP--------------------------QLSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLL 120

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 165 ESLSRIARNDTIVVVSTHDPNT-RDACTDIIDLKNYQ 200
Cdd:cd00267   121 ELLRELAEEGRTVIIVTHDPELaELAADRVIVLKDGK 157
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 5-198 1.80e-36

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 127.30  E-value: 1.80e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----------SMR----W 70
Cdd:cd03256     3 VENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDinklkgkalrQLRrqigM 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHGVAQRTAIDHVSLPLLAK--------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQ 142
Cdd:cd03256    83 IFQQFNLIERLSVLENVLSGRLGRrstwrslfGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQ 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTI-VVVSTHDPN-TRDACTDIIDLKN 198
Cdd:cd03256   163 PKLILADEPVASLDPASSRQVMDLLKRINREEGItVIVSLHQVDlAREYADRIVGLKD 220
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 3-184 2.46e-36

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 129.83  E-value: 2.46e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---------SMRWIFQ 73
Cdd:COG3842     6 LELENVSKRYGDVTAL-DDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDvtglppekrNVGMVFQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 N----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:COG3842    85 DyalfPH----LTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLLLD 160

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 150 EPTAQLDMHTAATVSESLSRI--ARNDTIVVVsTHDP 184
Cdd:COG3842   161 EPLSALDAKLREEMREELRRLqrELGITFIYV-THDQ 196
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 5-198 5.86e-36

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 124.95  E-value: 5.86e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYaDGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR---WIfqnphG-VAQ 80
Cdd:cd03235     2 VEDLTVSY-GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKerkRI-----GyVPQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDH---------VSLPLLAK----GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLML 147
Cdd:cd03235    76 RRSIDRdfpisvrdvVLMGLYGHkglfRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1447648657 148 VDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNT-RDACTDIIDLKN 198
Cdd:cd03235   156 LDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLvLEYFDRVLLLNR 207
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 3-198 6.21e-35

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 122.30  E-value: 6.21e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGhVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR----------WIF 72
Cdd:cd03264     1 LQLENLTKRYGKKRAL-DGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKqpqklrrrigYLP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 QNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:cd03264    79 QEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPT 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1447648657 153 AQLDMHTAATVSESLSRIARnDTIVVVSTHD-PNTRDACTDIIDLKN 198
Cdd:cd03264   159 AGLDPEERIRFRNLLSELGE-DRIVILSTHIvEDVESLCNQVAVLNK 204
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 3-191 9.59e-35

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 122.69  E-value: 9.59e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------------- 66
Cdd:cd03258     2 IELKNVSKVFGDTGGKVTalkDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDltllsgkelrkar 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  67 -SMRWIFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:cd03258    82 rRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIAR--NDTIVVVsTHDPNT-RDACT 191
Cdd:cd03258   162 LLCDEATSALDPETTQSILALLRDINRelGLTIVLI-THEMEVvKRICD 209
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 3-198 1.86e-34

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 119.80  E-value: 1.86e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGP-LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMR----W 70
Cdd:cd03228     1 IEFKNVSFSYPGRPkPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDlrdldleSLRkniaY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHgvaqrtaidhvslpLLAkglprreaeeqaRTLmdRFNLtrvtdrrfaeLSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:cd03228    81 VPQDPF--------------LFS------------GTI--RENI----------LSGGQRQRIAIARALLRDPPILILDE 122

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1447648657 151 PTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03228   123 ATSALDPETEALILEALRALAKGKTVIVI-AHRLSTIRDADRIIVLDD 169
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 3-184 4.30e-34

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 121.06  E-value: 4.30e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPL---LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SM 68
Cdd:COG1124     2 LEVRNLSVSYGQGGRrvpVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPvtrrrrkafrrRV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  69 RWIFQNPHGVA--QRTAIDHVSLPLLAKGLPRREaeEQARTLMDRFNLT-RVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:COG1124    82 QMVFQDPYASLhpRHTVDRILAEPLRIHGLPDRE--ERIAELLEQVGLPpSFLDRYPHQLSGGQRQRVAIARALILEPEL 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRI--ARNDTIVVVStHDP 184
Cdd:COG1124   160 LLLDEPTSALDVSVQAEILNLLKDLreERGLTYLFVS-HDL 199
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 18-196 6.04e-34

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 119.64  E-value: 6.04e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR---------------WIFQNPHGVAQRT 82
Cdd:TIGR03608  13 ILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPlnskkaskfrreklgYLFQNFALIENET 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:TIGR03608  93 VEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEPTGSLDPKNRDE 172

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 163 VSESLSRIARNDTIVVVSTHDPNTRDACTDIIDL 196
Cdd:TIGR03608 173 VLDLLLELNDEGKTIIIVTHDPEVAKQADRVIEL 206
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 3-183 1.26e-33

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 119.17  E-value: 1.26e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT---------RQGIDSMR---- 69
Cdd:cd03262     1 IEIKNLHKSFGDFHVL-KGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIidglkltddKKNINELRqkvg 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQN----PHgvaqRTAIDHVSL-PLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:cd03262    80 MVFQQfnlfPH----LTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPK 155

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:cd03262   156 VMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHE 194
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
11-196 2.03e-33

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 117.72  E-value: 2.03e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSmrwifqnPHGVAQRTAIDHvSLP 90
Cdd:NF040873    1 GYGGRPVL-HGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGAR-------VAYVPQRSEVPD-SLP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKGL--------------PRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:NF040873   72 LTVRDLvamgrwarrglwrrLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 157 MHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDIIDL 196
Cdd:NF040873  152 AESRERIIALLAEEHARGATVVVVTHDLELVRRADPCVLL 191
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 2-196 3.11e-33

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 123.94  E-value: 3.11e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGI-----------DSMRW 70
Cdd:TIGR02857 321 SLEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVpladadadswrDQIAW 400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHGVAQrTAIDHVslpLLAKGLPRREAEEQA--RTLMDRF------NLTRVTDRRFAELSGGEAQRLMLARAFAAQ 142
Cdd:TIGR02857 401 VPQHPFLFAG-TIAENI---RLARPDASDAEIREAleRAGLDEFvaalpqGLDTPIGEGGAGLSGGQAQRLALARAFLRD 476

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDIIDL 196
Cdd:TIGR02857 477 APLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLV-THRLALAALADRIVVL 529
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 4-198 3.40e-33

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 117.74  E-value: 3.40e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   4 DLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWI-FQNPHGVAQRT 82
Cdd:cd03226     1 RIENISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKErRKSIGYVMQDV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 A----IDHVSLPLL--AKGLPrrEAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:cd03226    81 DyqlfTDSVREELLlgLKELD--AGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLD 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1447648657 157 MHTAATVSESLSRIARNDTIVVVSTHDPN-TRDACTDIIDLKN 198
Cdd:cd03226   159 YKNMERVGELIRELAAQGKAVIVITHDYEfLAKVCDRVLLLAN 201
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
11-183 3.44e-33

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 118.76  E-value: 3.44e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYADGPLL---FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSMR-------------WIF 72
Cdd:PRK11629   14 RYQEGSVQtdvLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGqpMSKLSsaakaelrnqklgFIY 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 QNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:PRK11629   94 QFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEPT 173

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1447648657 153 AQLDMHTAATVSESLSRI-ARNDTIVVVSTHD 183
Cdd:PRK11629  174 GNLDARNADSIFQLLGELnRLQGTAFLVVTHD 205
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 8-183 4.26e-33

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 117.89  E-value: 4.26e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   8 VGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID--------------SMRWIFQ 73
Cdd:cd03292     6 VTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDvsdlrgraipylrrKIGVVFQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:cd03292    86 DFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTG 165

                         170       180       190
                  ....*....|....*....|....*....|
gi 1447648657 154 QLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:cd03292   166 NLDPDTTWEIMNLLKKINKAGTTVVVATHA 195
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 19-197 8.87e-33

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 117.15  E-value: 8.87e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT----RQGID----------SMR-----WIFQNPHGVA 79
Cdd:COG4778    27 LDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILvrhdGGWVDlaqaspreilALRrrtigYVSQFLRVIP 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 QRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLtrvtDRRFAEL-----SGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:COG4778   107 RVSALDVVAEPLLERGVDREEARARARELLARLNL----PERLWDLppatfSGGEQQRVNIARGFIADPPLLLLDEPTAS 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447648657 155 LDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDA-CTDIIDLK 197
Cdd:COG4778   183 LDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAvADRVVDVT 226
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 3-183 1.10e-32

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 122.32  E-value: 1.10e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGP----LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMRW- 70
Cdd:COG1123   261 LEVRNLSKRYPVRGkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDltklsrrSLREl 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ------IFQNPHG--VAQRTAIDHVSLPL-LAKGLPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFA 140
Cdd:COG1123   341 rrrvqmVFQDPYSslNPRMTVGDIIAEPLrLHGLLSRAERRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARALA 420

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 141 AQPSLMLVDEPTAQLDMHTAATVSESLSRIAR--NDTIVVVsTHD 183
Cdd:COG1123   421 LEPKLLILDEPTSALDVSVQAQILNLLRDLQRelGLTYLFI-SHD 464
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 3-183 3.50e-32

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 115.86  E-value: 3.50e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT---------RQGIDSMR---- 69
Cdd:COG1126     2 IEIENLHKSFGDLEVL-KGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITvdgedltdsKKDINKLRrkvg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQN----PHgvaqRTAIDHVSL-PLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:COG1126    81 MVFQQfnlfPH----LTVLENVTLaPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPK 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 145 LMLVDEPTAQLD--MhtaatVSESLS---RIARND-TIVVVsTHD 183
Cdd:COG1126   157 VMLFDEPTSALDpeL-----VGEVLDvmrDLAKEGmTMVVV-THE 195
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 3-182 8.63e-32

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 115.18  E-value: 8.63e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPG-HVyALTGPSGAGKSTLLGIIAGWTTPAEGQV-----TRQGIDSMRWIfqnph 76
Cdd:COG1119     4 LELRNVTVRRGGKTIL-DDISWTVKPGeHW-AILGPNGAGKSTLLSLITGDLPPTYGNDvrlfgERRGGEDVWEL----- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 gvaqRTAIDHVSLPLLAK-------------------GLPRR---EAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLM 134
Cdd:COG1119    77 ----RKRIGLVSPALQLRfprdetvldvvlsgffdsiGLYREptdEQRERARELLELLGLAHLADRPFGTLSQGEQRRVL 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1447648657 135 LARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVSTH 182
Cdd:COG1119   153 IARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGapTLVLVTHH 202
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 2-198 1.34e-31

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 120.32  E-value: 1.34e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYA-DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----SMRWIFQNPH 76
Cdd:COG2274   473 DIELENVSFRYPgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDlrqiDPASLRRQIG 552

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 GVAQ------RTAIDHVSLpllakGLPR------REAEEQA------RTLMDRFNlTRVTDRRfAELSGGEAQRLMLARA 138
Cdd:COG2274   553 VVLQdvflfsGTIRENITL-----GDPDatdeeiIEAARLAglhdfiEALPMGYD-TVVGEGG-SNLSGGQRQRLAIARA 625

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:COG2274   626 LLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIII-AHRLSTIRLADRIIVLDK 684
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 3-183 1.64e-31

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 114.26  E-value: 1.64e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---------SMRWIFQ 73
Cdd:cd03300     1 IELENVSKFYGGFVAL-DGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDitnlpphkrPVNTVFQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 N----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:cd03300    80 NyalfPH----LTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLD 155

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1447648657 150 EPTAQLDMHTAATVSESLSRIARN--DTIVVVsTHD 183
Cdd:cd03300   156 EPLGALDLKLRKDMQLELKRLQKElgITFVFV-THD 190
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 3-198 1.70e-31

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 112.49  E-value: 1.70e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNPHGVAQRT 82
Cdd:cd03230     1 IEVRNLSKRYGKKTAL-DDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKD----IKKEPEEVKRRI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIdhvslpllakgLPrreaeeQARTLMDRFnltrvTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03230    76 GY-----------LP------EEPSLYENL-----TVRENLKLSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRRE 133

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 163 VSESLSRIARNDTIVVVSTHdpNTRDA---CTDIIDLKN 198
Cdd:cd03230   134 FWELLRELKKEGKTILLSSH--ILEEAerlCDRVAILNN 170
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 3-183 4.42e-31

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 112.98  E-value: 4.42e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------------- 66
Cdd:cd03257     2 LEVKNLSVSFPTGGGSVKaldDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDllklsrrlrkirr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  67 -SMRWIFQNPHGV--AQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNL---TRVTDRRFAELSGGEAQRLMLARAFA 140
Cdd:cd03257    82 kEIQMVFQDPMSSlnPRMTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGVglpEEVLNRYPHELSGGQRQRVAIARALA 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 141 AQPSLMLVDEPTAQLDMHTAATVSESLSRIA--RNDTIVVVsTHD 183
Cdd:cd03257   162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQeeLGLTLLFI-THD 205
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 3-183 4.48e-31

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 118.08  E-value: 4.48e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPL-LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA---EGQVTRQGIDSMRW-------- 70
Cdd:COG1123     5 LEVRDLSVRYPGGDVpAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELsealrgrr 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ---IFQNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG1123    85 igmVFQDPmTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLL 164

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIARN-DTIVVVSTHD 183
Cdd:COG1123   165 IADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHD 202
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 3-184 2.83e-30

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 110.73  E-value: 2.83e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAG-----WTTPAEGQVTRQGIDSMRW------- 70
Cdd:cd03260     1 IELRDLNVYYGDKHAL-KDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGKDIYDLdvdvlel 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ------IFQNPHgVAQRTAIDHVSLPLLAKG-LPRREAEEQARTLMDRFNLT-RVTDRRFA-ELSGGEAQRLMLARAFAA 141
Cdd:cd03260    80 rrrvgmVFQKPN-PFPGSIYDNVAYGLRLHGiKLKEELDERVEEALRKAALWdEVKDRLHAlGLSGGQQQRLCLARALAN 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1447648657 142 QPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDP 184
Cdd:cd03260   159 EPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIV-THNM 200
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 1-184 6.14e-30

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 112.55  E-value: 6.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWI--------- 71
Cdd:COG1118     1 MSIEVRNISKRFGSFTLL-DDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTNLpprerrvgf 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 -FQN----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG1118    80 vFQHyalfPH----MTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVL 155

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIARNDTIVVV-STHDP 184
Cdd:COG1118   156 LLDEPFGALDAKVRKELRRWLRRLHDELGGTTVfVTHDQ 194
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
3-183 9.79e-30

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 109.80  E-value: 9.79e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------SMRWI----- 71
Cdd:PRK09493    2 IEFKNVSKHFGPTQVL-HNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKvndpkvDERLIrqeag 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 --FQNPHGVAQRTAIDHVSL-PLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK09493   81 mvFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1447648657 149 DEPTAQLD---MHTAATVSESLsriARNDTIVVVSTHD 183
Cdd:PRK09493  161 DEPTSALDpelRHEVLKVMQDL---AEEGMTMVIVTHE 195
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 3-193 1.21e-29

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 109.13  E-value: 1.21e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPllFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNPHGVA 79
Cdd:cd03263     1 LQIRNLTKTYKKGT--KPavdDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYS----IRTDRKAAR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 QR--------------TAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:cd03263    75 QSlgycpqfdalfdelTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSV 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARNDTIvVVSTHDPNTRDA-CTDI 193
Cdd:cd03263   155 LLLDEPTSGLDPASRRAIWDLILEVRKGRSI-ILTTHSMDEAEAlCDRI 202
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 5-196 1.26e-29

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 114.01  E-value: 1.26e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYAdGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGVAQRTAI 84
Cdd:COG0488     1 LENLSKSFG-GRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLRIGYLPQEPPLDDDLTVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHV--SLPLLAKGLPRRE------------------------------AEEQARTLMDRFNLTRVT-DRRFAELSGGEAQ 131
Cdd:COG0488    80 DTVldGDAELRALEAELEeleaklaepdedlerlaelqeefealggweAEARAEEILSGLGFPEEDlDRPVSELSGGWRR 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657 132 RLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRiaRNDTIVVVStHDpntRD----ACTDIIDL 196
Cdd:COG0488   160 RVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKN--YPGTVLVVS-HD---RYfldrVATRILEL 222
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 17-184 1.55e-29

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 108.54  E-value: 1.55e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  17 LLFHDLTASL-MPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV---------TRQGID------SMRWIFQN----PH 76
Cdd:cd03297    10 LPDFTLKIDFdLNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIvlngtvlfdSRKKINlppqqrKIGLVFQQyalfPH 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 -GVAQrtaidhvSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQL 155
Cdd:cd03297    90 lNVRE-------NLAFGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162

                         170       180       190
                  ....*....|....*....|....*....|
gi 1447648657 156 DMHTAATVSESLSRIARNDTIVVV-STHDP 184
Cdd:cd03297   163 DRALRLQLLPELKQIKKNLNIPVIfVTHDL 192
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 28-190 2.73e-29

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 108.33  E-value: 2.73e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR---------------WIFQNPHGVAQRTAIDHVSLPLL 92
Cdd:PRK10584   35 RGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQmdeearaklrakhvgFVFQSFMLIPTLNALENVELPAL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIAR 172
Cdd:PRK10584  115 LRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNR 194

                         170
                  ....*....|....*....
gi 1447648657 173 N-DTIVVVSTHDPNTRDAC 190
Cdd:PRK10584  195 EhGTTLILVTHDLQLAARC 213
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 2-184 5.58e-29

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 110.16  E-value: 5.58e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMrw 70
Cdd:COG3839     3 SLELENVSKSYGGVEAL-KDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDvtdlppkdrniAM-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQN----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG3839    80 VFQSyalyPH----MTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVF 155

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRI-ARNDTIVVVSTHDP 184
Cdd:COG3839   156 LLDEPLSNLDAKLRVEMRAEIKRLhRRLGTTTIYVTHDQ 194
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
5-183 7.37e-29

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 107.86  E-value: 7.37e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGI-----DSMRWI-FQNPHGV 78
Cdd:PRK11248    4 ISHLYADYGGKPAL-EDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKpvegpGAERGVvFQNEGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  79 AQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH 158
Cdd:PRK11248   83 PWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAF 162

                         170       180
                  ....*....|....*....|....*.
gi 1447648657 159 TAATVSESLSRI-ARNDTIVVVSTHD 183
Cdd:PRK11248  163 TREQMQTLLLKLwQETGKQVLLITHD 188
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-183 1.99e-28

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 106.87  E-value: 1.99e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADG---PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTR-----QGIDSMRWI- 71
Cdd:COG4525     2 SMLTVRHVSVRYPGGgqpQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLdgvpvTGPGADRGVv 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEP 151
Cdd:COG4525    82 FQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRFLLMDEP 161

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1447648657 152 TAQLDMHTAATVSESLSRI-ARNDTIVVVSTHD 183
Cdd:COG4525   162 FGALDALTREQMQELLLDVwQRTGKGVFLITHS 194
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 2-200 3.00e-28

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 110.63  E-value: 3.00e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGP-LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHG--- 77
Cdd:COG4987   333 SLELEDVSFRYPGAGrPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRria 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 -VAQRTAIDHVSLP---LLAKGlprrEA-EEQARTLMDRFNL------------TRV--TDRRfaeLSGGEAQRLMLARA 138
Cdd:COG4987   413 vVPQRPHLFDTTLRenlRLARP----DAtDEELWAALERVGLgdwlaalpdgldTWLgeGGRR---LSGGERRRLALARA 485

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDIIDLKNYQ 200
Cdd:COG4987   486 LLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLI-THRLAGLERMDRILVLEDGR 546
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 20-183 8.91e-28

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 105.12  E-value: 8.91e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----SMRWI--------FQNPHGVAQRTAIDHV 87
Cdd:COG0411    21 DDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDitglPPHRIarlgiartFQNPRLFPELTVLENV 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 SLPLLAK----------GLPR-----REAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:COG0411   101 LVAAHARlgrgllaallRLPRarreeREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEPKLLLLDEPA 180

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1447648657 153 AQLDMHTAATVSESLSRIARND--TIVVVStHD 183
Cdd:COG0411   181 AGLNPEETEELAELIRRLRDERgiTILLIE-HD 212
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
6-185 1.07e-27

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 104.81  E-value: 1.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   6 DHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQR---- 81
Cdd:COG4559     5 ENLSVRLGGRTLL-DDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAW---SPWELARRravl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 ----------TAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFA-------AQPS 144
Cdd:COG4559    81 pqhsslafpfTVEEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPR 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPN 185
Cdd:COG4559   161 WLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLN 201
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 5-196 1.25e-27

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 104.03  E-value: 1.25e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMRWIFQ 73
Cdd:PRK10247   10 LQNVGYLAGDAKIL-NNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDistlkpeiyrqQVSYCAQ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPhGVAQRTAIDHVSLPLLAkglpRREAEEQARTLMD--RFNLTRVT-DRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:PRK10247   89 TP-TLFGDTVYDNLIFPWQI----RNQQPDPAIFLDDleRFALPDTIlTKNIAELSGGEKQRISLIRNLQFMPKVLLLDE 163

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1447648657 151 PTAQLDMHTAATVSESLSRIARNDTIVVV-STHDPNTRDACTDIIDL 196
Cdd:PRK10247  164 ITSALDESNKHNVNEIIHRYVREQNIAVLwVTHDKDEINHADKVITL 210
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 3-192 1.61e-27

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 103.74  E-value: 1.61e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSM----------RW 70
Cdd:cd03261     1 IELRGLTKSFGGRTVL-KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGedISGLseaelyrlrrRM 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 --IFQNPHGVAQRTAIDHVSLPLLAKG-LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLML 147
Cdd:cd03261    80 gmLFQSGALFDSLTVFENVAFPLREHTrLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLL 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1447648657 148 VDEPTAQLDMHTAATVSESLSRIAR--NDTIVVVsTHDPNTRDACTD 192
Cdd:cd03261   160 YDEPTAGLDPIASGVIDDLIRSLKKelGLTSIMV-THDLDTAFAIAD 205
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 3-183 1.66e-27

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 103.92  E-value: 1.66e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW-----------I 71
Cdd:cd03295     1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQdpvelrrkigyV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQN----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVT--DRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:cd03295    81 IQQiglfPH----MTVEENIALVPKLLKWPKEKIRERADELLALVGLDPAEfaDRYPHELSGGQQQRVGVARALAADPPL 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIAR--NDTIVVVsTHD 183
Cdd:cd03295   157 LLMDEPFGALDPITRDQLQEEFKRLQQelGKTIVFV-THD 195
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 5-198 1.74e-27

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 101.91  E-value: 1.74e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADG-PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWiFQNPHGvaqrta 83
Cdd:cd03246     3 VENVSFRYPGAePPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQW-DPNELG------ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  84 iDHV-SLPllakglprREAEEQARTLMDrfNLtrvtdrrfaeLSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03246    76 -DHVgYLP--------QDDELFSGSIAE--NI----------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERA 134

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 163 VSESLSRI-ARNDTIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03246   135 LNQAIAALkAAGATRIVI-AHRPETLASADRILVLED 170
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 21-183 2.02e-27

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 103.67  E-value: 2.02e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWI------------FQNPHGVAQRTAIDHVS 88
Cdd:cd03219    18 DVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPpheiarlgigrtFQIPRLFPELTVLENVM 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  89 LPLLAKGLP----------RREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH 158
Cdd:cd03219    98 VAAQARTGSglllararreEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPE 177

                         170       180
                  ....*....|....*....|....*
gi 1447648657 159 TAATVSESLSRIARNDTIVVVSTHD 183
Cdd:cd03219   178 ETEELAELIRELRERGITVLLVEHD 202
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
28-183 4.59e-27

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 104.77  E-value: 4.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-----------------RQGIdSMrwIFQNPHGVAQRTAIDHVSLP 90
Cdd:COG1135    30 KGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLvdgvdltalserelraaRRKI-GM--IFQHFNLLSSRTVAENVALP 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRI 170
Cdd:COG1135   107 LEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDI 186

                         170
                  ....*....|....*..
gi 1447648657 171 arND----TIVVVsTHD 183
Cdd:COG1135   187 --NRelglTIVLI-THE 200
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 3-183 1.39e-26

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 99.95  E-value: 1.39e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPhgvAQRT 82
Cdd:cd03229     1 LELKNVSKRYGQKTVL-NDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELP---PLRR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVSlpllakglprreaeeQARTLMdrFNLTRVTDRRFAeLSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03229    77 RIGMVF---------------QDFALF--PHLTVLENIALG-LSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRRE 138

                         170       180
                  ....*....|....*....|..
gi 1447648657 163 VSESLSRIARNDTI-VVVSTHD 183
Cdd:cd03229   139 VRALLKSLQAQLGItVVLVTHD 160
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 19-183 1.55e-26

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 101.21  E-value: 1.55e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-----------------RQGI----------DSMRwI 71
Cdd:COG1127    21 LDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILvdgqditglsekelyelRRRIgmlfqggalfDSLT-V 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNphgvaqrtaidhVSLPLLA-KGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:COG1127   100 FEN------------VAFPLREhTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLYDE 167

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 151 PTAQLDMHTAATVSESLSRI--ARNDTIVVVsTHD 183
Cdd:COG1127   168 PTAGLDPITSAVIDELIRELrdELGLTSVVV-THD 201
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 3-183 2.97e-26

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 100.02  E-value: 2.97e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW---------IFQ 73
Cdd:cd03301     1 VELENVTKRFGNVTAL-DDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLppkdrdiamVFQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 N----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:cd03301    80 NyalyPH----MTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMD 155

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 150 EPTAQLDMHTAATVSESLSRIARN-DTIVVVSTHD 183
Cdd:cd03301   156 EPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHD 190
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 21-183 3.69e-26

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 100.23  E-value: 3.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEG-------QVTRQGIDSMRwIFQNPHGVAQRTAIDHVSLPL-- 91
Cdd:TIGR01184   3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGgvilegkQITEPGPDRMV-VFQNYSLLPWLTVRENIALAVdr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  92 LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA 171
Cdd:TIGR01184  82 VLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQIW 161

                         170
                  ....*....|...
gi 1447648657 172 R-NDTIVVVSTHD 183
Cdd:TIGR01184 162 EeHRVTVLMVTHD 174
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
5-189 4.44e-26

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 99.83  E-value: 4.44e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLFhDLTASlmPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMrwIFQ 73
Cdd:COG3840     4 LDDLTYRYGDFPLRF-DLTIA--AGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDltalppaerpvSM--LFQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 N----PH-GVAQRTAIDhvslplLAKGLpRREAEEQAR--TLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG3840    79 EnnlfPHlTVAQNIGLG------LRPGL-KLTAEQRAQveQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPIL 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1447648657 147 LVDEPTAQLDmhtAATVSESLSRIA-----RNDTIVVVsTHDPntRDA 189
Cdd:COG3840   152 LLDEPFSALD---PALRQEMLDLVDelcreRGLTVLMV-THDP--EDA 193
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 14-200 4.85e-26

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 99.48  E-value: 4.85e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTP---AEGQVTRQG--IDSM----RWI---FQ----NPH- 76
Cdd:COG4136    12 GGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGrrLTALpaeqRRIgilFQddllFPHl 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 GVAQRTAIDhvslplLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:COG4136    92 SVGENLAFA------LPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLD 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 157 MHTAATVSE-SLSRIARNDTIVVVSTHDPNTRDACTDIIDLKNYQ 200
Cdd:COG4136   166 AALRAQFREfVFEQIRQRGIPALLVTHDEEDAPAAGRVLDLGNWQ 210
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 21-195 5.54e-26

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 99.37  E-value: 5.54e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR----------WIFQNPHGVAQRTAIDHVSLP 90
Cdd:cd03265    18 GVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVReprevrrrigIVFQDLSVDDELTGWENLYIH 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRI 170
Cdd:cd03265    98 ARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKL 177

                         170       180
                  ....*....|....*....|....*....
gi 1447648657 171 -ARNDTIVVVSTHDPNTRDACTD---IID 195
Cdd:cd03265   178 kEEFGMTILLTTHYMEEAEQLCDrvaIID 206
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 21-198 1.32e-25

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 98.12  E-value: 1.32e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidsmrwifqNPHGVAQRTAIDHV------------- 87
Cdd:cd03269    18 DISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDG---------KPLDIAARNRIGYLpeerglypkmkvi 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 -SLPLLA--KGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVS 164
Cdd:cd03269    89 dQLVYLAqlKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELLK 168

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 165 ESLSRIARNDTIVVVSTHDPNT-RDACTDIIDLKN 198
Cdd:cd03269   169 DVIRELARAGKTVILSTHQMELvEELCDRVLLLNK 203
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 1-183 1.41e-25

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 98.95  E-value: 1.41e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR---------WI 71
Cdd:cd03296     1 MSIEVRNVSKRFGDFVAL-DDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDvpvqernvgFV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHGVAQRTAIDHVSLPLLAKGLPRR--EAEEQART--LMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLML 147
Cdd:cd03296    80 FQHYALFRHMTVFDNVAFGLRVKPRSERppEAEIRAKVheLLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLL 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 148 VDEPTAQLDmhtaATVSESLSRIAR--NDTIVVVS---THD 183
Cdd:cd03296   160 LDEPFGALD----AKVRKELRRWLRrlHDELHVTTvfvTHD 196
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 7-182 2.19e-25

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 97.67  E-value: 2.19e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   7 HVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwiFQNPHGVAQR----- 81
Cdd:cd03268     5 DLTKTYGKKRVL-DDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKS-----YQKNIEALRRigali 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 ---------TAIDHVSLPLLAKGLPRREAEEqartLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:cd03268    79 eapgfypnlTARENLRLLARLLGIRKKRIDE----VLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPT 154

                         170       180       190
                  ....*....|....*....|....*....|
gi 1447648657 153 AQLDMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:cd03268   155 NGLDPDGIKELRELILSLRDQGITVLISSH 184
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 3-198 2.41e-25

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 102.07  E-value: 2.41e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYaDGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTR----------QGIDSMRwif 72
Cdd:COG0488   316 LELEGLSKSY-GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLgetvkigyfdQHQEELD--- 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 qnphgvAQRTAIDHVSlpllakGLPRREAEEQARTLMDRFNLTRvtDRRF---AELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:COG0488   392 ------PDKTVLDELR------DGAPGGTEQEVRGYLGRFLFSG--DDAFkpvGVLSGGEKARLALAKLLLSPPNVLLLD 457

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 150 EPTAQLDMHTAATVSESLsriarND---TIVVVStHDpntRDA----CTDIIDLKN 198
Cdd:COG0488   458 EPTNHLDIETLEALEEAL-----DDfpgTVLLVS-HD---RYFldrvATRILEFED 504
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
2-180 2.63e-25

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 102.17  E-value: 2.63e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMR----W 70
Cdd:COG1132   339 EIEFENVSFSYPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDirdltleSLRrqigV 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHgVAQRTAIDHVSLpllakGLPR------REAEEQA------RTLMDRFNlTRVTDRrFAELSGGEAQRLMLARA 138
Cdd:COG1132   419 VPQDTF-LFSGTIRENIRY-----GRPDatdeevEEAAKAAqahefiEALPDGYD-TVVGER-GVNLSGGQRQRIAIARA 490

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS 180
Cdd:COG1132   491 LLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIVIA 532
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 25-183 3.25e-25

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 97.79  E-value: 3.25e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------SMR---WIFQN----PHgvaqRTAIDHVSLPL 91
Cdd:cd03299    21 EVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDitnlppEKRdisYVPQNyalfPH----MTVYKNIAYGL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  92 LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA 171
Cdd:cd03299    97 KKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELKKIR 176

                         170
                  ....*....|...
gi 1447648657 172 RN-DTIVVVSTHD 183
Cdd:cd03299   177 KEfGVTVLHVTHD 189
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
3-200 3.67e-25

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 97.25  E-value: 3.67e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR------------- 69
Cdd:PRK10908    2 IRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlknrevpflrrqi 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 -WIFQNPHGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK10908   82 gMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDpntrdacTDIIDLKNYQ 200
Cdd:PRK10908  162 DEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHD-------IGLISRRSYR 206
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 15-183 5.70e-25

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 97.51  E-value: 5.70e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  15 GPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVtRQG---IDSMR-----------------WIFQN 74
Cdd:PRK11264   15 GQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTI-RVGditIDTARslsqqkglirqlrqhvgFVFQN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  75 ----PHgvaqRTAIDHV-SLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:PRK11264   94 fnlfPH----RTVLENIiEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPEVILFD 169

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 150 EPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK11264  170 EPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHE 203
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 18-184 8.69e-25

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 95.70  E-value: 8.69e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA--EGQVTRQGIDSMRWIFQNPHG-VAQRtaiDHVslpllak 94
Cdd:cd03213    24 LLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLgvSGEVLINGRPLDKRSFRKIIGyVPQD---DIL------- 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 gLPRREAEEqarTLMDRFNLTRvtdrrfaeLSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARND 174
Cdd:cd03213    94 -HPTLTVRE---TLMFAAKLRG--------LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADTG 161

                         170
                  ....*....|
gi 1447648657 175 TIVVVSTHDP 184
Cdd:cd03213   162 RTIICSIHQP 171
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 17-184 1.26e-24

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 96.19  E-value: 1.26e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  17 LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAG---WTTPAEGQVTRQGIDSMRWIFQN--PHGVAQRTAIDHV---- 87
Cdd:cd03234    21 RILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFNGQPRKPDQFQKcvAYVRQDDILLPGLtvre 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 SLPLLAK-GLPRREAEEQ-----ARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAA 161
Cdd:cd03234   101 TLTYTAIlRLPRKSSDAIrkkrvEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTAL 180

                         170       180
                  ....*....|....*....|...
gi 1447648657 162 TVSESLSRIARNDTIVVVSTHDP 184
Cdd:cd03234   181 NLVSTLSQLARRNRIVILTIHQP 203
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 18-185 1.75e-24

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 96.38  E-value: 1.75e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQRTAI----DHVSLPLLA 93
Cdd:PRK13548   17 LLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADW---SPAELARRRAVlpqhSSLSFPFTV 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  94 K------GLPRREAEEQARTL----MDRFNLTRVTDRRFAELSGGEAQRLMLARAFA------AQPSLMLVDEPTAQLDM 157
Cdd:PRK13548   94 EevvamgRAPHGLSRAEDDALvaaaLAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDL 173

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 158 -HtaatvSESLSRIARNDTI-----VVVSTHDPN 185
Cdd:PRK13548  174 aH-----QHHVLRLARQLAHerglaVIVVLHDLN 202
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
1-183 2.02e-24

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 97.85  E-value: 2.02e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR---------WI 71
Cdd:PRK10851    1 MSIEIANIKKSFGRTQVL-NDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRlhardrkvgFV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHGVAQRTAIDHVSLPLlaKGLPRRE------AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:PRK10851   80 FQHYALFRHMTVFDNIAFGL--TVLPRRErpnaaaIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQI 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447648657 146 MLVDEPTAQLDmhtaATVSESLSRIARN------DTIVVVsTHD 183
Cdd:PRK10851  158 LLLDEPFGALD----AQVRKELRRWLRQlheelkFTSVFV-THD 196
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 21-185 2.66e-24

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 98.38  E-value: 2.66e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----SMRWIFQNPHGVAQ----------RTAIDH 86
Cdd:PRK09536   21 GVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDvealSARAASRRVASVPQdtslsfefdvRQVVEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  87 VSLPLLAKGLPRREAEEQA-RTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSE 165
Cdd:PRK09536  101 GRTPHRSRFDTWTETDRAAvERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDINHQVRTLE 180

                         170       180
                  ....*....|....*....|
gi 1447648657 166 SLSRIARNDTIVVVSTHDPN 185
Cdd:PRK09536  181 LVRRLVDDGKTAVAAIHDLD 200
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 20-185 3.96e-24

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 95.79  E-value: 3.96e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---------------SMRWIFQN----PHgvaq 80
Cdd:cd03294    41 NDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDiaamsrkelrelrrkKISMVFQSfallPH---- 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTA 160
Cdd:cd03294   117 RTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIR 196

                         170       180
                  ....*....|....*....|....*..
gi 1447648657 161 ATVSESLSRIARN--DTIVVVsTHDPN 185
Cdd:cd03294   197 REMQDELLRLQAElqKTIVFI-THDLD 222
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 3-198 8.57e-24

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 91.74  E-value: 8.57e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLlFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRqgidsmrwifqnphgvAQRT 82
Cdd:cd03221     1 IELENLSKTYGGKLL-LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTW----------------GSTV 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHvslpllakglprreaeeqartlmdrfnltrvtdrrFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03221    64 KIGY-----------------------------------FEQLSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEA 108

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 163 VSESLSRIarNDTIVVVStHDPNTRDA-CTDIIDLKN 198
Cdd:cd03221   109 LEEALKEY--PGTVILVS-HDRYFLDQvATKIIELED 142
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 3-183 1.03e-23

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 95.18  E-value: 1.03e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidsmrwifqNPHGVAQR- 81
Cdd:COG4152     2 LELKGLTKRFGDKTAV-DDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDG---------EPLDPEDRr 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 ---------------TAIDHvsLPLLA--KGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPS 144
Cdd:COG4152    72 rigylpeerglypkmKVGEQ--LVYLArlKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPE 149

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 145 LMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:COG4152   150 LLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQ 188
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 20-182 1.52e-23

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 95.64  E-value: 1.52e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID--------------SMRWIFQNPHGVAQRTAID 85
Cdd:PRK11153   22 NNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDltalsekelrkarrQIGMIFQHFNLLSSRTVFD 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSE 165
Cdd:PRK11153  102 NVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILE 181

                         170
                  ....*....|....*....
gi 1447648657 166 SLSRIAR--NDTIVVVsTH 182
Cdd:PRK11153  182 LLKDINRelGLTIVLI-TH 199
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 3-185 1.79e-23

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 93.61  E-value: 1.79e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQRT 82
Cdd:COG4604     2 IEIKNVSKRYGGKVVL-DDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATT---PSRELAKRL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AI----DHVSL-----PLLA-------KGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:COG4604    78 AIlrqeNHINSrltvrELVAfgrfpysKGRLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYV 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIAR--NDTIVVVsTHDPN 185
Cdd:COG4604   158 LLDEPLNNLDMKHSVQMMKLLRRLADelGKTVVIV-LHDIN 197
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
 12-183 2.68e-23

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 91.72  E-value: 2.68e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSMR-----------WIFQNPHGV 78
Cdd:TIGR01166   1 YPGGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGepLDYSRkgllerrqrvgLVFQDPDDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  79 AQRTAIDH-VSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDM 157
Cdd:TIGR01166  81 LFAADVDQdVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDP 160

                         170       180
                  ....*....|....*....|....*.
gi 1447648657 158 HTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:TIGR01166 161 AGREQMLAILRRLRAEGMTVVISTHD 186
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
21-198 3.64e-23

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 96.33  E-value: 3.64e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEG--QVTRQGIDSMR-------------WIFQNPHGVAQRTAID 85
Cdd:PRK10535   26 GISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGtyRVAGQDVATLDadalaqlrrehfgFIFQRYHLLSHLTAAQ 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSE 165
Cdd:PRK10535  106 NVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMA 185

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1447648657 166 SLSRIARNDTIVVVSTHDPNTRDACTDIIDLKN 198
Cdd:PRK10535  186 ILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD 218
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
3-183 6.66e-23

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 92.77  E-value: 6.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRY--ADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGI---DSMRW------- 70
Cdd:PRK13635    6 IRVEHISFRYpdAATYAL-KDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMvlsEETVWdvrrqvg 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 -IFQNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK13635   85 mVFQNPdNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIIL 164

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVS-THD 183
Cdd:PRK13635  165 DEATSMLDPRGRREVLETVRQLKEQKGITVLSiTHD 200
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 5-182 1.91e-22

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 94.14  E-value: 1.91e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYAdGPLLFHdltasLMPGHVYALTGPSGAGKSTLLGIIAGWTtPAEGQVTRQGID-------SMR----WIFQ 73
Cdd:PRK11174  358 LSPDGKTLA-GPLNFT-----LPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIElreldpeSWRkhlsWVGQ 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPHGVAQrTAIDHVslpLLAKGlprREAEEQARTLMDRFNLTRVTDR-----------RFAELSGGEAQRLMLARAFAAQ 142
Cdd:PRK11174  431 NPQLPHG-TLRDNV---LLGNP---DASDEQLQQALENAWVSEFLPLlpqgldtpigdQAAGLSVGQAQRLALARALLQP 503

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTH 182
Cdd:PRK11174  504 CQLLLLDEPTASLDAHSEQLVMQALNAASRRQTTLMV-TH 542
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 5-184 2.66e-22

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 93.58  E-value: 2.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDS-----------MRWIFQ 73
Cdd:TIGR02868 337 LRDLSAGYPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVssldqdevrrrVSVCAQ 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPHGVAQ------RTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNlTRVTDRRfAELSGGEAQRLMLARAFAAQPSLML 147
Cdd:TIGR02868 417 DAHLFDTtvrenlRLARPDATDEELWAALERVGLADWLRALPDGLD-TVLGEGG-ARLSGGERQRLALARALLADAPILL 494

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 148 VDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDP 184
Cdd:TIGR02868 495 LDEPTEHLDAETADELLEDLLAALSGRTVVLI-THHL 530
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 3-186 3.06e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 91.06  E-value: 3.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV---------TRQGIDSMR---- 69
Cdd:PRK13636    6 LKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRIlfdgkpidySRKGLMKLResvg 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK13636   86 MVFQDPdNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVL 165

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARN-DTIVVVSTHDPNT 186
Cdd:PRK13636  166 DEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDI 204
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 1-183 3.10e-22

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 90.07  E-value: 3.10e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLFhDLTASLMPGHVYALTGPSGAGKSTLLGI-------------IAGW-------TTPAEGQV 60
Cdd:PRK11124    1 MSIQLNGINCFYGAHQALF-DITLDCPQGETLVLLGPSGAGKSSLLRVlnllemprsgtlnIAGNhfdfsktPSDKAIRE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  61 TRQGIdSMrwIFQNPHGVAQRTAIDH-VSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAF 139
Cdd:PRK11124   80 LRRNV-GM--VFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARAL 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447648657 140 AAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK11124  157 MMEPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHE 200
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 3-182 3.15e-22

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 89.73  E-value: 3.15e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFH---DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMrwifQNPHGVA 79
Cdd:cd03266     2 ITADALTKRFRDVKKTVQavdGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVV----KEPAEAR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 QRTAIDHVSLPLLAK--------------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:cd03266    78 RRLGFVSDSTGLYDRltarenleyfaglyGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPV 157

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:cd03266   158 LLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTH 194
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 3-180 6.32e-22

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 89.08  E-value: 6.32e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRY-ADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----SMRWIFQNPHG 77
Cdd:cd03252     1 ITFEHVRFRYkPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDlalaDPAWLRRQVGV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 VAQ------RTAIDHVSLPllAKGLPRREAEEQARtLMDRFNLTR--------VTDRRFAELSGGEAQRLMLARAFAAQP 143
Cdd:cd03252    81 VLQenvlfnRSIRDNIALA--DPGMSMERVIEAAK-LAGAHDFISelpegydtIVGEQGAGLSGGQRQRIAIARALIHNP 157

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 144 SLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS 180
Cdd:cd03252   158 RILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIA 194
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
1-182 6.77e-22

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 91.05  E-value: 6.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGVAQ 80
Cdd:PRK13536   40 VAIDLAGVSKSYGDKAVV-NGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARARIGV 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPLLAK----------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:PRK13536  119 VPQFDNLDLEFTVRenllvfgryfGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDE 198

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1447648657 151 PTAQLDMHTAATVSESL-SRIARNDTIvVVSTH 182
Cdd:PRK13536  199 PTTGLDPHARHLIWERLrSLLARGKTI-LLTTH 230
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 22-185 1.08e-21

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 88.74  E-value: 1.08e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  22 LTASLMPGHVYALTGPSGAGKSTLLGIIAGwTTPAEGQVTRQGIDSMRWifqNPHGVAQRTAI--DHVSLP-------LL 92
Cdd:COG4138    15 ISAQVNAGELIHLIGPNGAGKSTLLARMAG-LLPGQGEILLNGRPLSDW---SAAELARHRAYlsQQQSPPfampvfqYL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKGLPRREAEEQARTLM----DRFNLTRVTDRRFAELSGGEAQRLMLARAFA-------AQPSLMLVDEPTAQLDMHTAA 161
Cdd:COG4138    91 ALHQPAGASSEAVEQLLaqlaEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLDEPMNSLDVAQQA 170

                         170       180
                  ....*....|....*....|....
gi 1447648657 162 TVSESLSRIARNDTIVVVSTHDPN 185
Cdd:COG4138   171 ALDRLLRELCQQGITVVMSSHDLN 194
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
1-183 1.33e-21

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 88.53  E-value: 1.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLFhDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT--------RQGIDSMR--- 69
Cdd:COG4161     1 MSIQLKNINCFYGSHQALF-DINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNiaghqfdfSQKPSEKAirl 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 ------WIFQNPHGVAQRTAIDH-VSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQ 142
Cdd:COG4161    80 lrqkvgMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMME 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:COG4161   160 PQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHE 200
anch_rpt_ABC TIGR03771
anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...
 25-190 1.47e-21

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 163483 [Multi-domain]  Cd Length: 223  Bit Score: 87.98  E-value: 1.47e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV------TRQGIDSMRWIFQNpHGVAQRTAID--HVSLPLLAKGL 96
Cdd:TIGR03771   2 SADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVkvagasPGKGWRHIGYVPQR-HEFAWDFPISvaHTVMSGRTGHI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  97 -----PRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA 171
Cdd:TIGR03771  81 gwlrrPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELFIELA 160

                         170       180
                  ....*....|....*....|
gi 1447648657 172 RNDTIVVVSTHD-PNTRDAC 190
Cdd:TIGR03771 161 GAGTAILMTTHDlAQAMATC 180
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 3-156 1.47e-21

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 87.55  E-value: 1.47e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFhDLTASlmPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMrwI 71
Cdd:cd03298     1 VRLDKIRFSYGEQPMHF-DLTFA--QGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDvtaappadrpvSM--L 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHGVAQRTAIDHVSLPlLAKGLPRREAEEQA-RTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:cd03298    76 FQENNLFAHLTVEQNVGLG-LSPGLKLTAEDRQAiEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDE 154


                  ....*.
gi 1447648657 151 PTAQLD 156
Cdd:cd03298   155 PFAALD 160
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
6-183 1.91e-21

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 88.59  E-value: 1.91e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   6 DHVGHRYADGPLL--------FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----------- 66
Cdd:PRK10419    7 SGLSHHYAHGGLSgkhqhqtvLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPlaklnraqrka 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  67 ---SMRWIFQNPHGV--AQRTAIDHVSLPLL-AKGLPRREAEEQARTLMDRFNLT-RVTDRRFAELSGGEAQRLMLARAF 139
Cdd:PRK10419   87 frrDIQMVFQDSISAvnPRKTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARAL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 140 AAQPSLMLVDEPTAQLDMHTAATVSESLSRI-ARNDTIVVVSTHD 183
Cdd:PRK10419  167 AVEPKLLILDEAVSNLDLVLQAGVIRLLKKLqQQFGTACLFITHD 211
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 22-184 2.04e-21

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 88.05  E-value: 2.04e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  22 LTASLMPGHVYALTGPSGAGKSTLLGI----IAGWTTP-AEGQVTRQGID-----------SMRWIFQNPHGVAQRTAID 85
Cdd:PRK14247   22 VNLEIPDNTITALMGPSGSGKSTLLRVfnrlIELYPEArVSGEVYLDGQDifkmdvielrrRVQMVFQIPNPIPNLSIFE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HVSLPL----LAKGlpRREAEEQARTLMDRFNL-TRVTDRRFA---ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDM 157
Cdd:PRK14247  102 NVALGLklnrLVKS--KKELQERVRWALEKAQLwDEVKDRLDApagKLSGGQQQRLCIARALAFQPEVLLADEPTANLDP 179

                         170       180
                  ....*....|....*....|....*..
gi 1447648657 158 HTAATVSESLSRIARNDTIVVVsTHDP 184
Cdd:PRK14247  180 ENTAKIESLFLELKKDMTIVLV-THFP 205
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 2-197 2.13e-21

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 91.02  E-value: 2.13e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAG-WTtPAEGQVTRQGIDSMRWIFQNPHgVAQ 80
Cdd:COG4178   362 ALALEDLTLRTPDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGlWP-YGSGRIARPAGARVLFLPQRPY-LPL 439

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPllakGLPRREAEEQARTLMDRFNLTRVTDRRFAE------LSGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:COG4178   440 GTLREALLYP----ATAEAFSDAELREALEAVGLGHLAERLDEEadwdqvLSLGEQQRLAFARLLLHKPDWLFLDEATSA 515

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1447648657 155 LDMHTAATVSESLSRIARNDTIVVVStHDPNTRDACTDIIDLK 197
Cdd:COG4178   516 LDEENEAALYQLLREELPGTTVISVG-HRSTLAAFHDRVLELT 557
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 1-184 3.00e-21

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 89.39  E-value: 3.00e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDhVGHRYADGPLlfhDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG---IDSMRWIFQNPHg 77
Cdd:COG4148     1 MMLEVD-FRLRRGGFTL---DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGevlQDSARGIFLPPH- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 vaQRtAIDHV----SL-PLL---------AKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQP 143
Cdd:COG4148    76 --RR-RIGYVfqeaRLfPHLsvrgnllygRKRAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSP 152

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1447648657 144 SLMLVDEPTAQLDMHTAATVSESLSRIARNDTI-VVVSTHDP 184
Cdd:COG4148   153 RLLLMDEPLAALDLARKAEILPYLERLRDELDIpILYVSHSL 194
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 3-179 3.86e-21

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 87.21  E-value: 3.86e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGP--LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsMRwiFQNPHGVaq 80
Cdd:cd03249     1 IEFKNVSFRYPSRPdvPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVD-IR--DLNLRWL-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSL-PLL---------AKGLPRREAEEQAR------------TLMDRFNlTRVTDRRFaELSGGEAQRLMLARA 138
Cdd:cd03249    76 RSQIGLVSQePVLfdgtiaeniRYGKPDATDEEVEEaakkanihdfimSLPDGYD-TLVGERGS-QLSGGQKQRIAIARA 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVV 179
Cdd:cd03249   154 LLRNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIVI 194
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 25-183 4.70e-21

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 88.19  E-value: 4.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTL----LGIIAGwTTPAEGQVTRQGID----------SMRW-----IFQNPHG----VaqR 81
Cdd:COG0444    27 DVRRGETLGLVGESGSGKSTLaraiLGLLPP-PGITSGEILFDGEDllklsekelrKIRGreiqmIFQDPMTslnpV--M 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 TAIDHVSLPLLA-KGLPRREAEEQARTLMDRFNLTRVTDR--RFA-ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDM 157
Cdd:COG0444   104 TVGDQIAEPLRIhGGLSKAEARERAIELLERVGLPDPERRldRYPhELSGGMRQRVMIARALALEPKLLIADEPTTALDV 183

                         170       180
                  ....*....|....*....|....*...
gi 1447648657 158 HTAATVSESLSRIAR--NDTIVVVsTHD 183
Cdd:COG0444   184 TIQAQILNLLKDLQRelGLAILFI-THD 210
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
14-183 7.07e-21

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 88.74  E-value: 7.07e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---------SMRWIFQN----PHgvaq 80
Cdd:PRK11607   30 DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDlshvppyqrPINMMFQSyalfPH---- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTA 160
Cdd:PRK11607  106 MTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLR 185

                         170       180
                  ....*....|....*....|....
gi 1447648657 161 ATVS-ESLSRIARNDTIVVVSTHD 183
Cdd:PRK11607  186 DRMQlEVVDILERVGVTCVMVTHD 209
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 2-194 9.99e-21

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 85.72  E-value: 9.99e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLL-FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqnpHGVAQ 80
Cdd:cd03245     2 RIEFRNVSFSYPNQEIPaLDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQL-----DPADL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSL-PLLAKG-------LPRREAEEQArtLMDRFNLTRVT----------DRRFAE----LSGGEAQRLMLARA 138
Cdd:cd03245    77 RRNIGYVPQdVTLFYGtlrdnitLGAPLADDER--ILRAAELAGVTdfvnkhpnglDLQIGErgrgLSGGQRQAVALARA 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDII 194
Cdd:cd03245   155 LLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIII-THRPSLLDLVDRII 209
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 10-179 1.01e-20

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 87.86  E-value: 1.01e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  10 HRYADgpllfHDLTASL-MPGH-VYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGI---DSMRWIFQNPHGVA----- 79
Cdd:TIGR02142   7 KRLGD-----FSLDADFtLPGQgVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRtlfDSRKGIFLPPEKRRigyvf 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 -QRTAIDHVSLPL-LAKGLPR-REAEEQAR--TLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:TIGR02142  82 qEARLFPHLSVRGnLRYGMKRaRPSERRISfeRVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAA 161

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447648657 155 LDMHTAAT------------------VSESLSRIAR-NDTIVVV 179
Cdd:TIGR02142 162 LDDPRKYEilpylerlhaefgipilyVSHSLQEVLRlADRVVVL 205
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 12-194 1.04e-20

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 86.64  E-value: 1.04e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGI------IAGWTTPAEGQVTRQGIDSMR-----------WIFQN 74
Cdd:PRK14246   19 YINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVlnrlieIYDSKIKVDGKVLYFGKDIFQidaiklrkevgMVFQQ 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  75 PHGVAQRTAIDHVSLPLLAKGLP-RREAEEQARTLMDRFNLTRVTDRRF----AELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:PRK14246   99 PNPFPHLSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVGLWKEVYDRLnspaSQLSGGQQQRLTIARALALKPKVLLMD 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 150 EPTAQLDMHTAATVSESLSRIARNDTIVVVStHDPNTRDACTDII 194
Cdd:PRK14246  179 EPTSMIDIVNSQAIEKLITELKNEIAIVIVS-HNPQQVARVADYV 222
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 3-198 1.34e-20

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 85.74  E-value: 1.34e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsMRWIFQNphgvAQRT 82
Cdd:cd03253     1 IEFENVTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQD-IREVTLD----SLRR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHV--SLPL--------LAKGLPR------REAEEQAR------TLMDRFNlTRVTDRRFaELSGGEAQRLMLARAFA 140
Cdd:cd03253    76 AIGVVpqDTVLfndtigynIRYGRPDatdeevIEAAKAAQihdkimRFPDGYD-TIVGERGL-KLSGGEKQRVAIARAIL 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1447648657 141 AQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03253   154 KNPPILLLDEATSALDTHTEREIQAALRDVSKGRTTIVI-AHRLSTIVNADKIIVLKD 210
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 11-183 1.96e-20

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 85.94  E-value: 1.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----SMRWI-------FQNPHG-V 78
Cdd:PRK13647   13 RYKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREvnaeNEKWVrskvglvFQDPDDqV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  79 AQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH 158
Cdd:PRK13647   93 FSSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPR 172

                         170       180
                  ....*....|....*....|....*
gi 1447648657 159 TAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK13647  173 GQETLMEILDRLHNQGKTVIVATHD 197
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 5-156 2.48e-20

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 84.90  E-value: 2.48e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQR--- 81
Cdd:cd03218     3 AENLSKRYGKRKVV-NGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKL---PMHKRARLgig 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 ------------TAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:cd03218    79 ylpqeasifrklTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLD 158


                  ....*..
gi 1447648657 150 EPTAQLD 156
Cdd:cd03218   159 EPFAGVD 165
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 15-199 2.73e-20

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 84.16  E-value: 2.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  15 GPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSmrwifQNPHGVAQRTAIDHVSL--PLL 92
Cdd:PRK13539   14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI-----DDPDVAEACHYLGHRNAmkPAL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 A-----------KGLPRREAEEQArtlmDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAA 161
Cdd:PRK13539   89 TvaenlefwaafLGGEELDIAAAL----EAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVA 164

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1447648657 162 TVSESLSRIARNDTIVVVSTHDPNTRDACTdIIDLKNY 199
Cdd:PRK13539  165 LFAELIRAHLAQGGIVIAATHIPLGLPGAR-ELDLGPF 201
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 14-184 3.81e-20

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 83.70  E-value: 3.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVtrqgidsmRWifqNPHGVAQRTAIDHVSLPLLA 93
Cdd:cd03231    11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRV--------LL---NGGPLDFQRDSIARGLLYLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  94 -----KG-LPRRE---------AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH 158
Cdd:cd03231    80 hapgiKTtLSVLEnlrfwhadhSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKA 159

                         170       180
                  ....*....|....*....|....*.
gi 1447648657 159 TAATVSESLSRIARNDTIVVVSTHDP 184
Cdd:cd03231   160 GVARFAEAMAGHCARGGMVVLTTHQD 185
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 2-194 3.82e-20

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 84.20  E-value: 3.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMR----W 70
Cdd:cd03254     2 EIEFENVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDirdisrkSLRsmigV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHgVAQRTAIDHVslpLLAKGLPRREAEEQARTL--MDRF--NLTRVTDRRFAE----LSGGEAQRLMLARAFAAQ 142
Cdd:cd03254    82 VLQDTF-LFSGTIMENI---RLGRPNATDEEVIEAAKEagAHDFimKLPNGYDTVLGEnggnLSQGERQLLAIARAMLRD 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVStHDPNT-RDActDII 194
Cdd:cd03254   158 PKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIA-HRLSTiKNA--DKI 207
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 3-179 5.14e-20

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 84.20  E-value: 5.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRY-ADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMRWIFQN 74
Cdd:cd03251     1 VEFKNVTFRYpGDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDvrdytlaSLRRQIGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  75 phgVAQRTAIDHVSLPL-LAKGLP---RREAEEQART-----LMDRFNL---TRVTDRRfAELSGGEAQRLMLARAFAAQ 142
Cdd:cd03251    81 ---VSQDVFLFNDTVAEnIAYGRPgatREEVEEAARAanaheFIMELPEgydTVIGERG-VKLSGGQRQRIAIARALLKD 156

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVV 179
Cdd:cd03251   157 PPILILDEATSALDTESERLVQAALERLMKNRTTFVI 193
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 25-156 1.12e-19

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 84.78  E-value: 1.12e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMRW-------IFQNPHGV--AQRTAIDHVS 88
Cdd:COG4608    40 DIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDitglsgrELRPlrrrmqmVFQDPYASlnPRMTVGDIIA 119

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  89 LPLLAKGL-PRREAEEQARTLMDRFNLTRVTDRRFA-ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:COG4608   120 EPLRIHGLaSKAERRERVAELLELVGLRPEHADRYPhEFSGGQRQRIGIARALALNPKLIVCDEPVSALD 189
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 31-184 1.57e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 83.35  E-value: 1.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  31 VYALTGPSGAGKSTLLG-----IIAGWTTPAEGQVTRQG-------IDSMR------WIFQNPHGVAQRTAIDHVSLPLL 92
Cdd:PRK14267   32 VFALMGPSGCGKSTLLRtfnrlLELNEEARVEGEVRLFGrniyspdVDPIEvrrevgMVFQYPNPFPHLTIYDNVAIGVK 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKGL--PRREAEEQARTLMDRFNL-TRVTDR---RFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES 166
Cdd:PRK14267  112 LNGLvkSKKELDERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEEL 191

                         170
                  ....*....|....*...
gi 1447648657 167 LSRIARNDTIVVVsTHDP 184
Cdd:PRK14267  192 LFELKKEYTIVLV-THSP 208
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 20-179 2.12e-19

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 82.10  E-value: 2.12e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSMRwifqnPHGVAQRtAIDHV---------- 87
Cdd:cd03224    17 FGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGrdITGLP-----PHERARA-GIGYVpegrrifpel 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 ----SLPLLAKGLPRREAEEQARTLMDRF-NLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03224    91 tveeNLLLGAYARRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEE 170

                         170
                  ....*....|....*...
gi 1447648657 163 VSESLSRIARND-TIVVV 179
Cdd:cd03224   171 IFEAIRELRDEGvTILLV 188
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
5-156 3.83e-19

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 81.55  E-value: 3.83e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLFhDLTASlmPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMrwIFQ 73
Cdd:PRK10771    4 LTDITWLYHHLPMRF-DLTVE--RGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDhtttppsrrpvSM--LFQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 N----PH-GVAQRTAIDhvslplLAKGLprREAEEQARTLMD---RFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:PRK10771   79 EnnlfSHlTVAQNIGLG------LNPGL--KLNAAQREKLHAiarQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPI 150

                         170
                  ....*....|.
gi 1447648657 146 MLVDEPTAQLD 156
Cdd:PRK10771  151 LLLDEPFSALD 161
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
19-181 4.94e-19

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 81.98  E-value: 4.94e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLL----GIIAGWTTPA------------EGQVTRQgIDSMR----WIFQNPHGV 78
Cdd:PRK09984   20 LHAVDLNIHHGEMVALLGPSGSGKSTLLrhlsGLITGDKSAGshiellgrtvqrEGRLARD-IRKSRantgYIFQQFNLV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  79 AQRTAIDHV------SLPLLAKGLP--RREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:PRK09984   99 NRLSVLENVligalgSTPFWRTCFSwfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAIARALMQQAKVILADE 178

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1447648657 151 PTAQLDMHTAATVSESLSRIARNDTIVVVST 181
Cdd:PRK09984  179 PIASLDPESARIVMDTLRDINQNDGITVVVT 209
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 28-156 5.28e-19

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 81.61  E-value: 5.28e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqnP-HGVAQR---------------TAIDHVSLPL 91
Cdd:COG1137    28 QGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHL----PmHKRARLgigylpqeasifrklTVEDNILAVL 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1447648657  92 LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:COG1137   104 ELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKFILLDEPFAGVD 168
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 18-189 5.30e-19

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 81.16  E-value: 5.30e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAG--WTTPAEGQVTrqgidsmrwIFQNPHGVaQRTAIDHVSL---PLL 92
Cdd:COG2401    45 VLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGalKGTPVAGCVD---------VPDNQFGR-EASLIDAIGRkgdFKD 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKGLprreaeeqartlmdrfnLTRV--TD-----RRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSE 165
Cdd:COG2401   115 AVEL-----------------LNAVglSDavlwlRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVAR 177

                         170       180
                  ....*....|....*....|....*
gi 1447648657 166 SLSRIARNDTI-VVVSTHDPNTRDA 189
Cdd:COG2401   178 NLQKLARRAGItLVVATHHYDVIDD 202
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
12-185 1.45e-18

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 80.83  E-value: 1.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----SMRWIFQN----------PHG 77
Cdd:PRK11231   12 YGTKRIL-NDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPismlSSRQLARRlallpqhhltPEG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 VAQRTAIDHVSLPLLAK-GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:PRK11231   91 ITVRELVAYGRSPWLSLwGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLD 170

                         170       180
                  ....*....|....*....|....*....
gi 1447648657 157 MHTAATVSESLSRIARNDTIVVVSTHDPN 185
Cdd:PRK11231  171 INHQVELMRLMRELNTQGKTVVTVLHDLN 199
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 21-195 1.95e-18

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 80.01  E-value: 1.95e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQR---------------TAID 85
Cdd:TIGR04406  19 DVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDITHL---PMHERARLgigylpqeasifrklTVEE 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HVSLPL-LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDmhtAATVS 164
Cdd:TIGR04406  96 NIMAVLeIRKDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILLDEPFAGVD---PIAVG 172

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1447648657 165 E--SLSRIARNDTIVVVSThDPNTRDAcTDIID 195
Cdd:TIGR04406 173 DikKIIKHLKERGIGVLIT-DHNVRET-LDICD 203
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 10-183 3.50e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 80.12  E-value: 3.50e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  10 HRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV----------------TRQ--GIdsmrwI 71
Cdd:PRK13639    9 YSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVlikgepikydkkslleVRKtvGI-----V 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHG-VAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:PRK13639   84 FQNPDDqLFAPTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDE 163

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1447648657 151 PTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK13639  164 PTSGLDPMGASQIMKLLYDLNKEGITIIISTHD 196
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
29-183 3.86e-18

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 79.63  E-value: 3.86e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  29 GHVYALTGPSGAGKSTLLGIIAGWTTPAEGQ--VTRQGIDSMR----------------------WIFQNPHGVAQRTAI 84
Cdd:PRK10619   31 GDVISIIGSSGSGKSTFLRCINFLEKPSEGSivVNGQTINLVRdkdgqlkvadknqlrllrtrltMVFQHFNLWSHMTVL 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHV-SLPLLAKGLPRREAEEQARTLMDRFNLT-RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:PRK10619  111 ENVmEAPIQVLGLSKQEARERAVKYLAKVGIDeRAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGE 190

                         170       180
                  ....*....|....*....|.
gi 1447648657 163 VSESLSRIARNDTIVVVSTHD 183
Cdd:PRK10619  191 VLRIMQQLAEEGKTMVVVTHE 211
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 29-190 5.89e-18

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 81.00  E-value: 5.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  29 GHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV-----------TRQGIDS-------MRWIFQN----PHgvaqRTAIDH 86
Cdd:TIGR03269 310 GEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnvrvgdewvdmTKPGPDGrgrakryIGILHQEydlyPH----RTVLDN 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  87 VSLPL---LAKGLPRREA----------EEQARTLMDRFnltrvTDrrfaELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:TIGR03269 386 LTEAIgleLPDELARMKAvitlkmvgfdEEKAEEILDKY-----PD----ELSEGERHRVALAQVLIKEPRIVILDEPTG 456

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 154 QLDMHTAATVSESL--SRIARNDTIVVVStHDPN-TRDAC 190
Cdd:TIGR03269 457 TMDPITKVDVTHSIlkAREEMEQTFIIVS-HDMDfVLDVC 495
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
3-156 9.85e-18

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 79.76  E-value: 9.85e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQ-------VTRQGIDSmRWI---F 72
Cdd:PRK11432    7 VVLKNITKRFGSNTVI-DNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQifidgedVTHRSIQQ-RDIcmvF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 QN----PHgvaqRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK11432   85 QSyalfPH----MSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLF 160


                  ....*...
gi 1447648657 149 DEPTAQLD 156
Cdd:PRK11432  161 DEPLSNLD 168
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 3-157 1.10e-17

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 78.23  E-value: 1.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQgiDSMRWIFqnphgVAQRT 82
Cdd:PRK09544    5 VSLENVSVSFGQRRVL-SDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRN--GKLRIGY-----VPQKL 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447648657  83 AIDhVSLPLLAKGLPR-REAEEQARTL--MDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDM 157
Cdd:PRK09544   77 YLD-TTLPLTVNRFLRlRPGTKKEDILpaLKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDV 153
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 6-194 1.10e-17

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 78.18  E-value: 1.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   6 DHVGHRYADGPLLFHDLtASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQvtRQGIDSMRWIFQNPHGVA-----Q 80
Cdd:cd03236     4 DEPVHRYGPNSFKLHRL-PVPREGQVLGLVGPNGIGKSTALKILAGKLKPNLGK--FDDPPDWDEILDEFRGSElqnyfT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVS----------LPLLAKG-----LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSL 145
Cdd:cd03236    81 KLLEGDVKvivkpqyvdlIPKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADF 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDII 194
Cdd:cd03236   161 YFFDEPSSYLDIKQRLNAARLIRELAEDDNYVLVVEHDLAVLDYLSDYI 209
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 1-182 1.24e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 78.52  E-value: 1.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRY-ADGP---LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT--------------- 61
Cdd:PRK13634    1 MDITFQKVEHRYqYKTPferRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTigervitagkknkkl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  62 ---RQ--GIdsmrwIFQNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTR-VTDRRFAELSGGEAQRLM 134
Cdd:PRK13634   81 kplRKkvGI-----VFQFPeHQLFEETVEKDICFGPMNFGVSEEDAKQKAREMIELVGLPEeLLARSPFELSGGQMRRVA 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1447648657 135 LARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIAR--NDTIVVVsTH 182
Cdd:PRK13634  156 IAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKekGLTTVLV-TH 204
PLN03211 PLN03211
ABC transporter G-25; Provisional
 22-187 2.12e-17

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 79.54  E-value: 2.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  22 LTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA---------EGQVTRQGIDSMRWIFQN----PHGVAQRTAIdHVS 88
Cdd:PLN03211   87 VTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnftgtilanNRKPTKQILKRTGFVTQDdilyPHLTVRETLV-FCS 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  89 LPLLAKGLPRREAEEQARTLMDRFNLTR-----VTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATV 163
Cdd:PLN03211  166 LLRLPKSLTKQEKILVAESVISELGLTKcentiIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRL 245

                         170       180
                  ....*....|....*....|....
gi 1447648657 164 SESLSRIARNDTIVVVSTHDPNTR 187
Cdd:PLN03211  246 VLTLGSLAQKGKTIVTSMHQPSSR 269
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 5-183 2.14e-17

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 77.41  E-value: 2.14e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT------RQGIDSMRWIFQNPHGV 78
Cdd:PRK11247   15 LNAVSKRYGERTVL-NQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLagtaplAEAREDTRLMFQDARLL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  79 AQRTAIDHVSLPLlaKGLPRREAEE--QARTLMDRFNltrvtdRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:PRK11247   94 PWKKVIDNVGLGL--KGQWRDAALQalAAVGLADRAN------EWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALD 165

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 157 mhtaatvseSLSRIARNDTI----------VVVSTHD 183
Cdd:PRK11247  166 ---------ALTRIEMQDLIeslwqqhgftVLLVTHD 193
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 18-187 2.57e-17

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 79.32  E-value: 2.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA---EGQVTRQGIDSMRWIFQNPHGVAQR--------TAIDH 86
Cdd:TIGR00955  40 LLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIDAKEMRAISAYVQQddlfiptlTVREH 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  87 VSLPLLAKgLPRREAEEQAR----TLMDRFNL-----TRV-TDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:TIGR00955 120 LMFQAHLR-MPRRVTKKEKRervdEVLQALGLrkcanTRIgVPGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLD 198

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1447648657 157 MHTAATVSESLSRIARNDTIVVVSTHDPNTR 187
Cdd:TIGR00955 199 SFMAYSVVQVLKGLAQKGKTIICTIHQPSSE 229
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
2-189 2.88e-17

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 79.23  E-value: 2.88e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMRW---- 70
Cdd:PRK13657  334 AVEFDDVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDirtvtraSLRRniav 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPhGVAQRTAIDHVSLpllakGLPR------REAEEQARTL------MDRFNlTRVTDRRfAELSGGEAQRLMLARA 138
Cdd:PRK13657  414 VFQDA-GLFNRSIEDNIRV-----GRPDatdeemRAAAERAQAHdfierkPDGYD-TVVGERG-RQLSGGERQRLAIARA 485

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDA 189
Cdd:PRK13657  486 LLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFIIAHRLSTVRNA 536
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
8-183 3.33e-17

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 77.35  E-value: 3.33e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   8 VGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV---------TRQGIDSMRW----IFQN 74
Cdd:PRK13638    7 LWFRYQDEPVL-KGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVlwqgkpldySKRGLLALRQqvatVFQD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  75 PHGVAQRTAIDH-VSLPLLAKGLPRreaEEQARTLMDRfnLTRVTDRRFAE-----LSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK13638   86 PEQQIFYTDIDSdIAFSLRNLGVPE---AEITRRVDEA--LTLVDAQHFRHqpiqcLSHGQKKRVAIAGALVLQARYLLL 160

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK13638  161 DEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHD 195
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
20-198 3.67e-17

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 76.95  E-value: 3.67e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNphgVAQRTAI---------DHVSLP 90
Cdd:PRK10253   24 ENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKE---VARRIGLlaqnattpgDITVQE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKG-LP--------RREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAA 161
Cdd:PRK10253  101 LVARGrYPhqplftrwRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQI 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 162 TVSESLSRIARNDTIVVVST-HDPNtrDAC---TDIIDLKN 198
Cdd:PRK10253  181 DLLELLSELNREKGYTLAAVlHDLN--QACryaSHLIALRE 219
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 20-179 4.24e-17

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 76.17  E-value: 4.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDSMRwifqnPHGVAQRtAIDHVslP------- 90
Cdd:COG0410    20 HGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGedITGLP-----PHRIARL-GIGYV--Pegrrifp 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 -------LLAKGLPRREAEEQARTL---MDRF-NLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHT 159
Cdd:COG0410    92 sltveenLLLGAYARRDRAEVRADLervYELFpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLGLAPLI 171

                         170       180
                  ....*....|....*....|.
gi 1447648657 160 AATVSESLSRIARND-TIVVV 179
Cdd:COG0410   172 VEEIFEIIRRLNREGvTILLV 192
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 22-185 5.01e-17

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 76.51  E-value: 5.01e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  22 LTASLMPGHVYALTGPSGAGKSTLLGIIAGwTTPAEGQVTRQGIDSMRWifqNPHGVAQRTA--IDHVSLPL-------L 92
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQPLEAW---SAAELARHRAylSQQQTPPFampvfqyL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKGLPRREAEEQARTLMD----RFNLTRVTDRRFAELSGGEAQRLMLARAF-----AAQPS--LMLVDEPTAQLDMHTAA 161
Cdd:PRK03695   91 TLHQPDKTRTEAVASALNevaeALGLDDKLGRSVNQLSGGEWQRVRLAAVVlqvwpDINPAgqLLLLDEPMNSLDVAQQA 170

                         170       180
                  ....*....|....*....|....
gi 1447648657 162 TVSESLSRIARNDTIVVVSTHDPN 185
Cdd:PRK03695  171 ALDRLLSELCQQGIAVVMSSHDLN 194
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 21-183 7.04e-17

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 75.83  E-value: 7.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSmrWIFQNPH----GV--AQRT-------AIDhv 87
Cdd:cd03267    39 GISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVP--WKRRKKFlrriGVvfGQKTqlwwdlpVID-- 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 SLPLLAK--GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSE 165
Cdd:cd03267   115 SFYLLAAiyDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRN 194

                         170
                  ....*....|....*....
gi 1447648657 166 SLSRIARN-DTIVVVSTHD 183
Cdd:cd03267   195 FLKEYNRErGTTVLLTSHY 213
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 3-183 1.25e-16

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 77.28  E-value: 1.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADgPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-------------RQGIDSMR 69
Cdd:TIGR03719 323 IEAENLTKAFGD-KLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEigetvklayvdqsRDALDPNK 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQNPHGvaqrtAIDHVSLpllakglprREAEEQARTLMDRFNLtRVTD--RRFAELSGGEAQRLMLARAFAAQPSLML 147
Cdd:TIGR03719 402 TVWEEISG-----GLDIIKL---------GKREIPSRAYVGRFNF-KGSDqqKKVGQLSGGERNRVHLAKTLKSGGNVLL 466

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1447648657 148 VDEPTAQLDMHTAATVSESLSRIARNdtiVVVSTHD 183
Cdd:TIGR03719 467 LDEPTNDLDVETLRALEEALLNFAGC---AVVISHD 499
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 2-198 1.84e-16

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 76.71  E-value: 1.84e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRY--ADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNPHGVA 79
Cdd:COG4618   330 RLSVENLTVVPpgSKRPIL-RGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGAD----LSQWDREEL 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 QRtaidHVS-LP----LLA----------KGLPRREAEEQART-----LMDRFNL---TRVTDRRFAeLSGGEAQRLMLA 136
Cdd:COG4618   405 GR----HIGyLPqdveLFDgtiaeniarfGDADPEKVVAAAKLagvheMILRLPDgydTRIGEGGAR-LSGGQRQRIGLA 479

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447648657 137 RAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDIIDLKN 198
Cdd:COG4618   480 RALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRPSLLAAVDKLLVLRD 541
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
25-156 2.12e-16

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 76.60  E-value: 2.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT---------------RQGIdSMrwIFQNPHGVAQRTAIDHVSL 89
Cdd:COG1129    26 ELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILldgepvrfrsprdaqAAGI-AI--IHQELNLVPNLSVAENIFL 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  90 ---PLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:COG1129   103 grePRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDARVLILDEPTASLT 172
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 2-197 2.65e-16

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 76.30  E-value: 2.65e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGP--LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNPHGVA 79
Cdd:TIGR00958 478 LIEFQDVSFSYPNRPdvPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVP----LVQYDHHYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 QRtaidHVSL----PLL---------AKGLPRREAEE-QARTLM---DRF--NLTRVTDRRFAE----LSGGEAQRLMLA 136
Cdd:TIGR00958 554 HR----QVALvgqePVLfsgsvreniAYGLTDTPDEEiMAAAKAanaHDFimEFPNGYDTEVGEkgsqLSGGQKQRIAIA 629

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 137 RAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARndTIVVVsTHDPNTRDACTDIIDLK 197
Cdd:TIGR00958 630 RALVRKPRVLILDEATSALDAECEQLLQESRSRASR--TVLLI-AHRLSTVERADQILVLK 687
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
3-182 3.27e-16

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 74.84  E-value: 3.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADgPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidsmRWIFQNPHGVAQRT 82
Cdd:PRK13537    8 IDFRNVEKRYGD-KLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCG----EPVPSRARHARQRV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AI----DHV--------SLPLLAK--GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK13537   83 GVvpqfDNLdpdftvreNLLVFGRyfGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVL 162

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 149 DEPTAQLDMHTAATVSESL-SRIARNDTIvVVSTH 182
Cdd:PRK13537  163 DEPTTGLDPQARHLMWERLrSLLARGKTI-LLTTH 196
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 19-182 3.71e-16

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 72.73  E-value: 3.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGI------DSMRWIF----QNPHgvaqrtaidhvs 88
Cdd:cd03247    18 LKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVpvsdleKALSSLIsvlnQRPY------------ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  89 lpLLAKglprreaeeqarTLMDrfNLtrvtDRRFaelSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLS 168
Cdd:cd03247    86 --LFDT------------TLRN--NL----GRRF---SGGERQRLALARILLQDAPIVLLDEPTVGLDPITERQLLSLIF 142

                         170
                  ....*....|....
gi 1447648657 169 RIARNDTIVVVSTH 182
Cdd:cd03247   143 EVLKDKTLIWITHH 156
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 3-182 4.03e-16

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 72.08  E-value: 4.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDSMRWIFQNPHGvAQRT 82
Cdd:cd03216     1 LELRGITKRFGGVKAL-DGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEIL---VDGKEVSFASPRD-ARRA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVSlpllakglprreaeeqartlmdrfnltrvtdrrfaELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03216    76 GIAMVY-----------------------------------QLSVGERQMVEIARALARNARLLILDEPTAALTPAEVER 120

                         170       180
                  ....*....|....*....|
gi 1447648657 163 VSESLSRIARNDTIVVVSTH 182
Cdd:cd03216   121 LFKVIRRLRAQGVAVIFISH 140
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
5-183 5.26e-16

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 74.15  E-value: 5.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHG-VAQRTA 83
Cdd:PRK15056    9 VNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLVAyVPQSEE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  84 IDHvSLPLLAK-----------GLPRReAEEQARTLMD----RFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK15056   89 VDW-SFPVLVEdvvmmgryghmGWLRR-AKKRDRQIVTaalaRVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILL 166

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK15056  167 DEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHN 201
cbiO PRK13640
energy-coupling factor transporter ATPase;
3-196 1.11e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 73.30  E-value: 1.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPL-LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR------W----- 70
Cdd:PRK13640    6 VEFKHVSFTYPDSKKpALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKITVDGITltaktvWdirek 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 ---IFQNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:PRK13640   86 vgiVFQNPdNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKII 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS-THDPNTRDACTDIIDL 196
Cdd:PRK13640  166 ILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISiTHDIDEANMADQVLVL 216
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
34-183 1.13e-15

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 73.83  E-value: 1.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  34 LTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---------SMRWIFQN----PHgvaqRTAIDHVSLPLLAKGLPRRE 100
Cdd:PRK09452   45 LLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDithvpaenrHVNTVFQSyalfPH----MTVFENVAFGLRMQKTPAAE 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 101 AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIAR--NDTIVV 178
Cdd:PRK09452  121 ITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRklGITFVF 200


                  ....*
gi 1447648657 179 VsTHD 183
Cdd:PRK09452  201 V-THD 204
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 22-191 1.15e-15

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 74.66  E-value: 1.15e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   22 LTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG---IDSMRWIFQNPHGVAQRTAID-------HVSLPL 91
Cdd:TIGR01257 1958 LCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGksiLTNISDVHQNMGYCPQFDAIDdlltgreHLYLYA 2037

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   92 LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA 171
Cdd:TIGR01257 2038 RLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSII 2117

                          170       180
                   ....*....|....*....|.
gi 1447648657  172 RNDTIVVVSTHDPNTRDA-CT 191
Cdd:TIGR01257 2118 REGRAVVLTSHSMEECEAlCT 2138
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 20-182 1.17e-15

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 72.76  E-value: 1.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLL-------GIIAGWTTpaEGQVTRQGID---------SMR----WIFQNP---- 75
Cdd:COG1117    28 KDINLDIPENKVTALIGPSGCGKSTLLrclnrmnDLIPGARV--EGEILLDGEDiydpdvdvvELRrrvgMVFQKPnpfp 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  76 -------------HGVAQRTAIDHV---SLpllakglprREA---EEqartlmdrfnltrVTDR--RFA-ELSGGEAQRL 133
Cdd:COG1117   106 ksiydnvayglrlHGIKSKSELDEIveeSL---------RKAalwDE-------------VKDRlkKSAlGLSGGQQQRL 163

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 134 MLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTH 182
Cdd:COG1117   164 CIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIV-TH 211
cbiO PRK13649
energy-coupling factor transporter ATPase;
1-156 1.19e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 73.24  E-value: 1.19e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYA-----DGPLLFhDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-----------RQG 64
Cdd:PRK13649    1 MGINLQNVSYTYQagtpfEGRALF-DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRvddtlitstskNKD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  65 IDSMR----WIFQNPHG-VAQRTAIDHVSLPLLAKGLPRREAEEQARtlmDRFNLTRVTDRRFA----ELSGGEAQRLML 135
Cdd:PRK13649   80 IKQIRkkvgLVFQFPESqLFEETVLKDVAFGPQNFGVSQEEAEALAR---EKLALVGISESLFEknpfELSGGQMRRVAI 156

                         170       180
                  ....*....|....*....|.
gi 1447648657 136 ARAFAAQPSLMLVDEPTAQLD 156
Cdd:PRK13649  157 AGILAMEPKILVLDEPTAGLD 177
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 28-182 1.69e-15

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 72.02  E-value: 1.69e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGwtTPA----EGQVTRQGIDSMRW------------IFQNP---HGVAQ----RTAI 84
Cdd:COG0396    25 PGEVHAIMGPNGSGKSTLAKVLMG--HPKyevtSGSILLDGEDILELspderaragiflAFQYPveiPGVSVsnflRTAL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHVSLPLLakglPRREAEEQARTLMDRFNLtrvtDRRFAE------LSGGEAQRL----MLARafaaQPSLMLVDEPTAQ 154
Cdd:COG0396   103 NARRGEEL----SAREFLKLLKEKMKELGL----DEDFLDryvnegFSGGEKKRNeilqMLLL----EPKLAILDETDSG 170

                         170       180
                  ....*....|....*....|....*...
gi 1447648657 155 LDMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:COG0396   171 LDIDALRIVAEGVNKLRSPDRGILIITH 198
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 14-184 1.97e-15

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 71.24  E-value: 1.97e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRwifQNPHGVAQRTAIDHvsLPLLA 93
Cdd:TIGR01189  11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAE---QRDEPHENILYLGH--LPGLK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  94 KGLPRRE-----------AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:TIGR01189  86 PELSALEnlhfwaaihggAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVAL 165

                         170       180
                  ....*....|....*....|..
gi 1447648657 163 VSESLSRIARNDTIVVVSTHDP 184
Cdd:TIGR01189 166 LAGLLRAHLARGGIVLLTTHQD 187
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
14-182 2.47e-15

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 70.99  E-value: 2.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID----------SMRWIFQNPhGVAQR-T 82
Cdd:PRK13538   12 DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPirrqrdeyhqDLLYLGHQP-GIKTElT 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVSLPLLAKGLPRREAEEQArtlMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:PRK13538   91 ALENLRFYQRLHGPGDDEALWEA---LAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVAR 167

                         170       180
                  ....*....|....*....|
gi 1447648657 163 VSESLSRIARNDTIVVVSTH 182
Cdd:PRK13538  168 LEALLAQHAEQGGMVILTTH 187
cbiO PRK13644
energy-coupling factor transporter ATPase;
3-183 2.55e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 72.33  E-value: 2.55e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW------------ 70
Cdd:PRK13644    2 IRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFsklqgirklvgi 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHG-VAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVD 149
Cdd:PRK13644   82 VFQNPETqFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 150 EPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK13644  162 EVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHN 195
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 20-163 4.76e-15

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 72.41  E-value: 4.76e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTL----LGIIagwttPAEGQVTRQGID--------------SMRWIFQNPHG---- 77
Cdd:COG4172   303 DGVSLTLRRGETLGLVGESGSGKSTLglalLRLI-----PSEGEIRFDGQDldglsrralrplrrRMQVVFQDPFGslsp 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 ---VAQrtaIdhVSLPL--LAKGLPRREAEEQARTLMDRFNLTRVTDRRF-AELSGGEAQRLMLARAFAAQPSLMLVDEP 151
Cdd:COG4172   378 rmtVGQ---I--IAEGLrvHGPGLSAAERRARVAEALEEVGLDPAARHRYpHEFSGGQRQRIAIARALILEPKLLVLDEP 452

                         170
                  ....*....|..
gi 1447648657 152 TAQLDMHTAATV 163
Cdd:COG4172   453 TSALDVSVQAQI 464
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 2-182 4.89e-15

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 70.58  E-value: 4.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGP--LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidsmRWIFQNPH--- 76
Cdd:cd03248    11 IVKFQNVTFAYPTRPdtLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDG----KPISQYEHkyl 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 -----GVAQ------RTAIDHVSLPLLAKGLPRREAEEQ---ARTLMDRFNLTRVTD--RRFAELSGGEAQRLMLARAFA 140
Cdd:cd03248    87 hskvsLVGQepvlfaRSLQDNIAYGLQSCSFECVKEAAQkahAHSFISELASGYDTEvgEKGSQLSGGQKQRVAIARALI 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1447648657 141 AQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:cd03248   167 RNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHR 208
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 6-183 8.95e-15

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 70.34  E-value: 8.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   6 DHVGHRYADGpLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDS----------------MR 69
Cdd:PRK11701   10 RGLTKLYGPR-KGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRDGqlrdlyalseaerrrlLR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 --WIF--QNP-HGV-AQRTAIDHVSLPLLAKGLPR-REAEEQARTLMDR--FNLTRVTD--RRFaelSGGEAQRLMLARA 138
Cdd:PRK11701   89 teWGFvhQHPrDGLrMQVSAGGNIGERLMAVGARHyGDIRATAGDWLERveIDAARIDDlpTTF---SGGMQQRLQIARN 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARN-DTIVVVSTHD 183
Cdd:PRK11701  166 LVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHD 211
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 2-179 9.30e-15

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 71.77  E-value: 9.30e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRY-ADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDSmrwifQNPHGVAQ 80
Cdd:COG5265   357 EVRFENVSFGYdPERPIL-KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRIL---IDG-----QDIRDVTQ 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 ---RTAI-----DHVslpL--------LAKGLP---RREAEEQAR---------TLMDRFNlTRVTDRRFaELSGGEAQR 132
Cdd:COG5265   428 aslRAAIgivpqDTV---LfndtiaynIAYGRPdasEEEVEAAARaaqihdfieSLPDGYD-TRVGERGL-KLSGGEKQR 502

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1447648657 133 LMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVV 179
Cdd:COG5265   503 VAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVARGRTTLVI 549
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 8-198 9.60e-15

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 69.87  E-value: 9.60e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   8 VGHRYAdgpllFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidSMRWIFQNPHGV-AQRTAIDH 86
Cdd:cd03220    32 VGEFWA-----LKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG--RVSSLLGLGGGFnPELTGREN 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  87 VSLPLLAKGLPRREAEEqartLMDR---FN-LTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03220   105 IYLNGRLLGLSRKEIDE----KIDEiieFSeLGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEK 180

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 163 VSESLSRIARNDTIVVVSTHDPNT-RDACTDIIDLKN 198
Cdd:cd03220   181 CQRRLRELLKQGKTVILVSHDPSSiKRLCDRALVLEK 217
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 25-153 1.01e-14

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 71.60  E-value: 1.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT---------------RQGIdSMrwIFQNPHGVAQRTAIDHVSL 89
Cdd:COG3845    27 TVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILidgkpvrirsprdaiALGI-GM--VHQHFMLVPNLTVAENIVL 103

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447648657  90 ---PLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:COG3845   104 glePTKGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILDEPTA 170
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 26-156 1.71e-14

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 69.63  E-value: 1.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  26 LMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT---------------RQGIdsMRwIFQNPHGVAQRTAID----- 85
Cdd:PRK11300   28 VREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILlrgqhieglpghqiaRMGV--VR-TFQHVRLFREMTVIEnllva 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 ---HVSLPLLAkGL--------PRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:PRK11300  105 qhqQLKTGLFS-GLlktpafrrAESEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAG 183


                  ..
gi 1447648657 155 LD 156
Cdd:PRK11300  184 LN 185
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 12-183 1.72e-14

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 69.73  E-value: 1.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLfHDLTASLMPGHVYALTGPSGAGKS----TLLGIIAGWTTPAEGQVTRQGI----DSMR-----WIFQNPHGV 78
Cdd:PRK10418   13 QAAQPLV-HGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKpvapCALRgrkiaTIMQNPRSA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  79 AQ--RTAIDHVSLPLLAKGLPRREAeeQARTLMDRFNLT---RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:PRK10418   92 FNplHTMHTHARETCLALGKPADDA--TLTAALEAVGLEnaaRVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTT 169

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1447648657 154 QLDMHTAATVSESLSRIARNDTI-VVVSTHD 183
Cdd:PRK10418  170 DLDVVAQARILDLLESIVQKRALgMLLVTHD 200
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 5-200 2.95e-14

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 70.20  E-value: 2.95e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-RQGIdSMRWIFQnpHGVAQRTA 83
Cdd:PRK10636  315 MEKVSAGYGDRIIL-DSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGlAKGI-KLGYFAQ--HQLEFLRA 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  84 iDHVSLPLLAKGLPRrEAEEQARTLMDRFNLT--RVTD--RRFaelSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHT 159
Cdd:PRK10636  391 -DESPLQHLARLAPQ-ELEQKLRDYLGGFGFQgdKVTEetRRF---SGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDM 465

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1447648657 160 AATVSESLsrIARNDTIVVVStHDPNTRDACTDII-------------DLKNYQ 200
Cdd:PRK10636  466 RQALTEAL--IDFEGALVVVS-HDRHLLRSTTDDLylvhdgkvepfdgDLEDYQ 516
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 20-183 3.21e-14

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 70.10  E-value: 3.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKS----TLLGIIAGWTTPAEGQVTRQGID-----------------SMrwIFQ----- 73
Cdd:COG4172    27 KGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDllglserelrrirgnriAM--IFQepmts 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 -NPHgvaqRTAIDHVSLPL-LAKGLPRREAEEQARTLMDRfnlTRVTD--RRFA----ELSGGEAQRLMLARAFAAQPSL 145
Cdd:COG4172   105 lNPL----HTIGKQIAEVLrLHRGLSGAAARARALELLER---VGIPDpeRRLDayphQLSGGQRQRVMIAMALANEPDL 177

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRI-ARNDTIVVVSTHD 183
Cdd:COG4172   178 LIADEPTTALDVTVQAQILDLLKDLqRELGMALLLITHD 216
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
21-183 3.42e-14

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 70.06  E-value: 3.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---------------SMRWIFQNPHGVAQRTAID 85
Cdd:PRK10070   46 DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDiakisdaelrevrrkKIAMVFQSFALMPHMTVLD 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSE 165
Cdd:PRK10070  126 NTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQD 205

                         170
                  ....*....|....*....
gi 1447648657 166 SLSRI-ARNDTIVVVSTHD 183
Cdd:PRK10070  206 ELVKLqAKHQRTIVFISHD 224
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 15-181 3.76e-14

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 67.46  E-value: 3.76e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  15 GPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGvAQRTAIDHVSlpllak 94
Cdd:cd03215    12 VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRR---SPRD-AIRAGIAYVP------ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQARTLMDRFNLTRVtdrrfaeLSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARND 174
Cdd:cd03215    82 EDRKREGLVLDLSVAENIALSSL-------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAG 154


                  ....*...
gi 1447648657 175 T-IVVVST 181
Cdd:cd03215   155 KaVLLISS 162
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 19-194 5.16e-14

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 68.18  E-value: 5.16e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidSMRWIFQ-----NPhgvaQRTAIDHVSLPLLA 93
Cdd:COG1134    42 LKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNG--RVSALLElgagfHP----ELTGRENIYLNGRL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  94 KGLPRREAEEqartLMDrfnltRVTDrrFAEL-----------SGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:COG1134   116 LGLSRKEIDE----KFD-----EIVE--FAELgdfidqpvktySSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKK 184

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1447648657 163 VSESL-SRIARNDTIVVVStHDPNT-RDACTDII 194
Cdd:COG1134   185 CLARIrELRESGRTVIFVS-HSMGAvRRLCDRAI 217
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
2-180 8.46e-14

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 68.98  E-value: 8.46e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEG--------------QVTRQGI-- 65
Cdd:PRK10790  340 RIDIDNVSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGeirldgrplsslshSVLRQGVam 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  66 ---------DSMrwiFQN--------PHGVAQrtAIDHVSLPLLAKGLP---RREAEEQARTlmdrfnltrvtdrrfaeL 125
Cdd:PRK10790  420 vqqdpvvlaDTF---LANvtlgrdisEEQVWQ--ALETVQLAELARSLPdglYTPLGEQGNN-----------------L 477

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1447648657 126 SGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS 180
Cdd:PRK10790  478 SVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIA 532
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 3-183 9.19e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 67.85  E-value: 9.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRY-ADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQ-------VTRQGIDSMR----W 70
Cdd:PRK13648    8 IVFKNVSFQYqSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEifynnqaITDDNFEKLRkhigI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPHG--VAQRTAIDhVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK13648   88 VFQNPDNqfVGSIVKYD-VAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIIL 166

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1447648657 149 DEPTAQLDMHTAATVSESLSRIARNDTIVVVS-THD 183
Cdd:PRK13648  167 DEATSMLDPDARQNLLDLVRKVKSEHNITIISiTHD 202
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
19-152 9.51e-14

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 68.89  E-value: 9.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDSMRWIFQNP-----HGVA-------------Q 80
Cdd:COG1129   268 VRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIR---LDGKPVRIRSPrdairAGIAyvpedrkgeglvlD 344

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447648657  81 RTAIDHVSLPLLAKG-----LPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:COG1129   345 LSIRENITLASLDRLsrgglLDRRRERALAEEYIKRLRIkTPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPT 422
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 20-180 9.88e-14

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 67.49  E-value: 9.88e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGII--AGWTTP---AEGQVTRQG--IDSMR-----------WIFQNPHGVAQr 81
Cdd:PRK14239   22 NSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPevtITGSIVYNGhnIYSPRtdtvdlrkeigMVFQQPNPFPM- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 TAIDHVSLPLLAKGLPRREAEEQA--RTLMDRFNLTRVTDRRFAE---LSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:PRK14239  101 SIYENVVYGLRLKGIKDKQVLDEAveKSLKGASIWDEVKDRLHDSalgLSGGQQQRVCIARVLATSPKIILLDEPTSALD 180

                         170       180
                  ....*....|....*....|....
gi 1447648657 157 MHTAATVSESLSRIARNDTIVVVS 180
Cdd:PRK14239  181 PISAGKIEETLLGLKDDYTMLLVT 204
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 18-187 1.38e-13

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 66.11  E-value: 1.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAgwttpaegqvtrqgidsmrwifqnphgvaQRTAIDHVSLPLLAKGLP 97
Cdd:cd03232    22 LLNNISGYVKPGTLTALMGESGAGKTTLLDVLA-----------------------------GRKTAGVITGEILINGRP 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  98 RREA-------EEQARTLMDrfNLTRVTDRRFA----ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES 166
Cdd:cd03232    73 LDKNfqrstgyVEQQDVHSP--NLTVREALRFSallrGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRF 150

                         170       180
                  ....*....|....*....|.
gi 1447648657 167 LSRIARNDTIVVVSTHDPNTR 187
Cdd:cd03232   151 LKKLADSGQAILCTIHQPSAS 171
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
26-183 1.43e-13

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 68.30  E-value: 1.43e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  26 LMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQgIDsmrwIFQNPhgvaQRTAIDH---VSLPLlakglprREAE 102
Cdd:PRK13409  362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LK----ISYKP----QYIKPDYdgtVEDLL-------RSIT 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 103 EQART------LMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARND-- 174
Cdd:PRK13409  426 DDLGSsyykseIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEERea 505


                  ....*....
gi 1447648657 175 TIVVVStHD 183
Cdd:PRK13409  506 TALVVD-HD 513
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 21-172 1.54e-13

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 67.81  E-value: 1.54e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR-----W---------IFQNP-HGVAQRTAI- 84
Cdd:PRK15079   39 GVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGmkddeWravrsdiqmIFQDPlASLNPRMTIg 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHVSLPLLA--KGLPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAA 161
Cdd:PRK15079  119 EIIAEPLRTyhPKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQA 198

                         170
                  ....*....|.
gi 1447648657 162 TVSESLSRIAR 172
Cdd:PRK15079  199 QVVNLLQQLQR 209
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 18-189 1.91e-13

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 66.65  E-value: 1.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW-----------IFQNP-HGVAQRTAI- 84
Cdd:COG1101    21 ALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLpeykrakyigrVFQDPmMGTAPSMTIe 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHVSLPL-------LAKGLPRREaEEQARTLMDRFNL---TRVTDrRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:COG1101   101 ENLALAYrrgkrrgLRRGLTKKR-RELFRELLATLGLgleNRLDT-KVGLLSGGQRQALSLLMATLTKPKLLLLDEHTAA 178

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1447648657 155 LDMHTAATVSESLSRIARND---TIVVvsTHdpNTRDA 189
Cdd:COG1101   179 LDPKTAALVLELTEKIVEENnltTLMV--TH--NMEQA 212
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 3-183 2.04e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 66.94  E-value: 2.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADG-PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEG-------QVTRQGIDSMR----W 70
Cdd:PRK13632    8 IKVENVSFSYPNSeNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGeikidgiTISKENLKEIRkkigI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQNPH----GVaqrTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLM 146
Cdd:PRK13632   88 IFQNPDnqfiGA---TVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEII 164

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1447648657 147 LVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS-THD 183
Cdd:PRK13632  165 IFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISiTHD 202
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 29-183 2.58e-13

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 66.28  E-value: 2.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  29 GHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNPHGVA--QRTAIDHvslpLLAKGLPRREAEEQAR 106
Cdd:cd03237    25 SEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDT----VSYKPQYIKadYEGTVRD----LLSSITKDFYTHPYFK 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 107 T-LMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVStHD 183
Cdd:cd03237    97 TeIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENNekTAFVVE-HD 175
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 28-183 2.68e-13

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 67.50  E-value: 2.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG-----IDSMRWI-----FQNphgVAQ---RTA-----IDHVsl 89
Cdd:COG1245    98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYDEEPswdevLKRFRGTelqdyFKK---LANgeiKVAhkpqyVDLI-- 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  90 PLLAKGLPR---REAEE--QARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVS 164
Cdd:COG1245   173 PKVFKGTVRellEKVDErgKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVA 252

                         170
                  ....*....|....*....
gi 1447648657 165 ESLSRIARNDTIVVVSTHD 183
Cdd:COG1245   253 RLIRELAEEGKYVLVVEHD 271
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 21-190 3.00e-13

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 66.07  E-value: 3.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT---------------RQGIDsmrWIFQNPHGVAQRTAID 85
Cdd:PRK10895   21 DVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIiddedisllplharaRRGIG---YLPQEASIFRRLSVYD 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HVSLPL-LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVS 164
Cdd:PRK10895   98 NLMAVLqIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPISVIDIK 177

                         170       180
                  ....*....|....*....|....*..
gi 1447648657 165 ESLSRIARNDTIVVVSTHD-PNTRDAC 190
Cdd:PRK10895  178 RIIEHLRDSGLGVLITDHNvRETLAVC 204
cbiO PRK13643
energy-coupling factor transporter ATPase;
21-182 3.07e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 66.68  E-value: 3.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV-----------TRQGIDSMR----WIFQNPHG-VAQRTAI 84
Cdd:PRK13643   24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVtvgdivvsstsKQKEIKPVRkkvgVVFQFPESqLFEETVL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHVSLPLLAKGLPRREAEEQARTLMDRFNLTR-VTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATV 163
Cdd:PRK13643  104 KDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADeFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIEM 183

                         170
                  ....*....|....*....
gi 1447648657 164 SESLSRIARNDTIVVVSTH 182
Cdd:PRK13643  184 MQLFESIHQSGQTVVLVTH 202
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 5-183 3.67e-13

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 67.27  E-value: 3.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQ-GIdSMRWIFQNPH------- 76
Cdd:TIGR03719   7 MNRVSKVVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQpGI-KVGYLPQEPQldptktv 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 ------GVAQ-RTAIDHVSLPLLAKGLPRRE----AEEQARtLMDR------FNLTRVTDR------------RFAELSG 127
Cdd:TIGR03719  86 renveeGVAEiKDALDRFNEISAKYAEPDADfdklAAEQAE-LQEIidaadaWDLDSQLEIamdalrcppwdaDVTKLSG 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 128 GEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIArnDTIVVVsTHD 183
Cdd:TIGR03719 165 GERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYP--GTVVAV-THD 217
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 11-180 4.48e-13

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 65.13  E-value: 4.48e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYA-DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNP-HGVAQRTAI---D 85
Cdd:cd03369    15 RYApDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGID----ISTIPlEDLRSSLTIipqD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 hvslPLLAKGlprreaeeQARTLMDRFNltRVTDR------RFAE----LSGGEAQRLMLARAFAAQPSLMLVDEPTAQL 155
Cdd:cd03369    91 ----PTLFSG--------TIRSNLDPFD--EYSDEeiygalRVSEgglnLSQGQRQLLCLARALLKRPRVLVLDEATASI 156

                         170       180
                  ....*....|....*....|....*
gi 1447648657 156 DMHTAATVSESLSRIARNDTIVVVS 180
Cdd:cd03369   157 DYATDALIQKTIREEFTNSTILTIA 181
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 14-184 4.95e-13

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 66.75  E-value: 4.95e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTT--PAEGQV------------------------------T 61
Cdd:TIGR03269  11 DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGRIiyhvalcekcgyverpskvgepcpvcggtlE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  62 RQGID-----------SMRWI---FQNPHGV-AQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELS 126
Cdd:TIGR03269  91 PEEVDfwnlsdklrrrIRKRIaimLQRTFALyGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLSHRITHIARDLS 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657 127 GGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTI-VVVSTHDP 184
Cdd:TIGR03269 171 GGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGIsMVLTSHWP 229
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 25-163 5.05e-13

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 66.14  E-value: 5.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID--------------SMRWIFQNPHGV--AQRTAIDHVS 88
Cdd:PRK11308   37 TLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDllkadpeaqkllrqKIQIVFQNPYGSlnPRKKVGQILE 116

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447648657  89 LPLLAK-GLPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATV 163
Cdd:PRK11308  117 EPLLINtSLSAAERREKALAMMAKVGLrPEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQV 193
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 2-181 5.48e-13

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 66.59  E-value: 5.48e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV-------TRQGIDSMR----- 69
Cdd:COG3845   257 VLEVENLSVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIrldgediTGLSPRERRrlgva 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQNPHG--------VAQRTAIDHVSLPLLAKG--LPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARA 138
Cdd:COG3845   337 YIPEDRLGrglvpdmsVAENLILGRYRRPPFSRGgfLDRKAIRAFAEELIEEFDVrTPGPDTPARSLSGGNQQKVILARE 416

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLsrIARND---TIVVVST 181
Cdd:COG3845   417 LSRDPKLLIAAQPTRGLDVGAIEFIHQRL--LELRDagaAVLLISE 460
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
28-194 5.86e-13

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 66.37  E-value: 5.86e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG-----IDSMRW---------IFQNPHGVAQRT-AIDHvsLPLL 92
Cdd:PRK13409   98 EGKVTGILGPNGIGKTTAVKILSGELIPNLGDYEEEPswdevLKRFRGtelqnyfkkLYNGEIKVVHKPqYVDL--IPKV 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKG-----LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESL 167
Cdd:PRK13409  176 FKGkvrelLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNVARLI 255

                         170       180
                  ....*....|....*....|....*..
gi 1447648657 168 SRIARNDTIVVVStHDPNTRDACTDII 194
Cdd:PRK13409  256 RELAEGKYVLVVE-HDLAVLDYLADNV 281
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 2-180 6.12e-13

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 66.66  E-value: 6.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRY-ADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNphgvaQ 80
Cdd:TIGR02203 330 DVEFRNVTFRYpGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLAS-----L 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPL----------LAKGLPRREAEEQARTLMDRFNLTRVTDR-----------RFAELSGGEAQRLMLARAF 139
Cdd:TIGR02203 405 RRQVALVSQDVvlfndtiannIAYGRTEQADRAEIERALAAAYAQDFVDKlplgldtpigeNGVLLSGGQRQRLAIARAL 484

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 140 AAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS 180
Cdd:TIGR02203 485 LKDAPILILDEATSALDNESERLVQAALERLMQGRTTLVIA 525
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 30-183 7.04e-13

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 65.19  E-value: 7.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  30 HVYALTGPSGAGKSTLL-------GIIAGWTtpAEGQVTRQG-------IDSMR------WIFQNPHGVAqRTAIDHVSL 89
Cdd:PRK14243   37 QITAFIGPSGCGKSTILrcfnrlnDLIPGFR--VEGKVTFHGknlyapdVDPVEvrrrigMVFQKPNPFP-KSIYDNIAY 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  90 PLLAKGLPRREAEEQARTLMDRFNLTRVTDR---RFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES 166
Cdd:PRK14243  114 GARINGYKGDMDELVERSLRQAALWDEVKDKlkqSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEEL 193

                         170
                  ....*....|....*..
gi 1447648657 167 LSRIARNDTIVVVsTHD 183
Cdd:PRK14243  194 MHELKEQYTIIIV-THN 209
cbiO PRK13650
energy-coupling factor transporter ATPase;
21-183 8.17e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 65.14  E-value: 8.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG----IDSMrW--------IFQNP-HGVAQRTAIDHV 87
Cdd:PRK13650   25 DVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGdlltEENV-WdirhkigmVFQNPdNQFVGATVEDDV 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 SLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESL 167
Cdd:PRK13650  104 AFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTI 183

                         170
                  ....*....|....*..
gi 1447648657 168 SRIARNDTIVVVS-THD 183
Cdd:PRK13650  184 KGIRDDYQMTVISiTHD 200
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 8-156 1.03e-12

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 65.88  E-value: 1.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   8 VGHRYAdgpllFHDLTASLMPGHVYALTGPSGAGKST----LLGIIAgwttpAEGQVTRQGIDSMRW------------- 70
Cdd:PRK15134  296 VDHNVV-----VKNISFTLRPGETLGLVGESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLnrrqllpvrhriq 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 -IFQNPHG-------VAQrtaIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRF-AELSGGEAQRLMLARAFAA 141
Cdd:PRK15134  366 vVFQDPNSslnprlnVLQ---IIEEGLRVHQPTLSAAQREQQVIAVMEEVGLDPETRHRYpAEFSGGQRQRIAIARALIL 442

                         170
                  ....*....|....*
gi 1447648657 142 QPSLMLVDEPTAQLD 156
Cdd:PRK15134  443 KPSLIILDEPTSSLD 457
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
17-183 1.08e-12

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 64.79  E-value: 1.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  17 LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV----------TRQGI----DSMRWIFQNPHGVAQRT 82
Cdd:PRK11831   21 CIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEIlfdgenipamSRSRLytvrKRMSMLFQSGALFTDMN 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVSLPLLAKG-LPrrEAEEQARTLM--DRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHT 159
Cdd:PRK11831  101 VFDNVAYPLREHTqLP--APLLHSTVMMklEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPIT 178

                         170       180
                  ....*....|....*....|....*.
gi 1447648657 160 AATVSESLSRI--ARNDTIVVVStHD 183
Cdd:PRK11831  179 MGVLVKLISELnsALGVTCVVVS-HD 203
cbiO PRK13642
energy-coupling factor transporter ATPase;
25-183 1.97e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 64.34  E-value: 1.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEG-------QVTRQGIDSMR----WIFQNP-HGVAQRTAIDHVSLPLL 92
Cdd:PRK13642   29 SITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGkvkidgeLLTAENVWNLRrkigMVFQNPdNQFVGATVEDDVAFGME 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 AKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIAR 172
Cdd:PRK13642  109 NQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKE 188

                         170
                  ....*....|..
gi 1447648657 173 NDTIVVVS-THD 183
Cdd:PRK13642  189 KYQLTVLSiTHD 200
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
5-185 2.68e-12

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 63.65  E-value: 2.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYAdGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWifqNPHGVAQRTAI 84
Cdd:PRK10575   14 LRNVSFRVP-GRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESW---SSKAFARKVAY 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 DHVSLP---------LLAKG-------LPR-----REAEEQARTLMDrfnLTRVTDRRFAELSGGEAQRLMLARAFAAQP 143
Cdd:PRK10575   90 LPQQLPaaegmtvreLVAIGrypwhgaLGRfgaadREKVEEAISLVG---LKPLAHRLVDSLSGGERQRAWIAMLVAQDS 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1447648657 144 SLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVST-HDPN 185
Cdd:PRK10575  167 RCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVlHDIN 209
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 20-182 4.26e-12

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 62.16  E-value: 4.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGW--TTPAEGQVTRQGID---------SMRWI---FQNP---HGVaqrt 82
Cdd:cd03217    17 KGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDitdlppeerARLGIflaFQYPpeiPGV---- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 aidhvslpllakglprreaeeqarTLMDrfnLTRVTDRRFaelSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:cd03217    93 ------------------------KNAD---FLRYVNEGF---SGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRL 142

                         170       180
                  ....*....|....*....|
gi 1447648657 163 VSESLSRIARNDTIVVVSTH 182
Cdd:cd03217   143 VAEVINKLREEGKSVLIITH 162
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 14-180 4.98e-12

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 61.40  E-value: 4.98e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPG-HVYaLTGPSGAGKSTLLGIIAG-WTTpAEGQVTR-QGIDSMrwiFqnphgVAQRtaidhvslP 90
Cdd:cd03223    12 DGRVLLKDLSFEIKPGdRLL-ITGPSGTGKSSLFRALAGlWPW-GSGRIGMpEGEDLL---F-----LPQR--------P 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKGLPRreaeEQ-ARTLMDrfnltrvtdrrfaELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATvsesLSR 169
Cdd:cd03223    74 YLPLGTLR----EQlIYPWDD-------------VLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDR----LYQ 132

                         170
                  ....*....|.
gi 1447648657 170 IARNDTIVVVS 180
Cdd:cd03223   133 LLKELGITVIS 143
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
36-183 5.51e-12

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 63.51  E-value: 5.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  36 GPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDSMR------------WIFQN----PH-GVAqrtaiDHVSLPLLAKGLPR 98
Cdd:PRK11000   36 GPSGCGKSTLLRMIAGLEDITSGDLF---IGEKRmndvppaergvgMVFQSyalyPHlSVA-----ENMSFGLKLAGAKK 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  99 REAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDmhtAATVSESLSRIAR-----N 173
Cdd:PRK11000  108 EEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLD---AALRVQMRIEISRlhkrlG 184

                         170
                  ....*....|
gi 1447648657 174 DTIVVVsTHD 183
Cdd:PRK11000  185 RTMIYV-THD 193
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 25-183 5.94e-12

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 63.65  E-value: 5.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQ----------GIDSmrwifqnphgvaQRTAIDhvslpLLAK 94
Cdd:COG1245   362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDlkisykpqyiSPDY------------DGTVEE-----FLRS 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQART-LMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARN 173
Cdd:COG1245   425 ANTDDFGSSYYKTeIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAEN 504

                         170
                  ....*....|..
gi 1447648657 174 D--TIVVVStHD 183
Cdd:COG1245   505 RgkTAMVVD-HD 515
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
20-157 6.50e-12

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 62.97  E-value: 6.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASL-MPGH-VYALTGPSGAGKSTLLGIIAGWTTPAEGQV---------TRQGID------SMRWIFQN----PH-- 76
Cdd:PRK11144   13 LCLTVNLtLPAQgITAIFGRSGAGKTSLINAISGLTRPQKGRIvlngrvlfdAEKGIClppekrRIGYVFQDarlfPHyk 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  77 -------GVAQRTAI---DHVSL----PLLakglprreaeeqartlmDRFNLTrvtdrrfaeLSGGEAQRLMLARAFAAQ 142
Cdd:PRK11144   93 vrgnlryGMAKSMVAqfdKIVALlgiePLL-----------------DRYPGS---------LSGGEKQRVAIGRALLTA 146

                         170
                  ....*....|....*
gi 1447648657 143 PSLMLVDEPTAQLDM 157
Cdd:PRK11144  147 PELLLMDEPLASLDL 161
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 20-183 7.02e-12

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 62.80  E-value: 7.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-------RQGIDSMRWIfqnphGV--AQRT-------A 83
Cdd:COG4586    39 DDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRvlgyvpfKRRKEFARRI-----GVvfGQRSqlwwdlpA 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  84 IDhvSLPLLAK--GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAA 161
Cdd:COG4586   114 ID--SFRLLKAiyRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKE 191

                         170       180
                  ....*....|....*....|...
gi 1447648657 162 TVSESLSRI-ARNDTIVVVSTHD 183
Cdd:COG4586   192 AIREFLKEYnRERGTTILLTSHD 214
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 33-183 8.35e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 62.51  E-value: 8.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  33 ALTGPSGAGKSTLLGIIAGWTTPAEGQV-------TRQGIDSMR----WIFQNPHG------VAQRTAIDHVSLpllakG 95
Cdd:PRK13652   34 AVIGPNGAGKSTLFRHFNGILKPTSGSVlirgepiTKENIREVRkfvgLVFQNPDDqifsptVEQDIAFGPINL-----G 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  96 LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA-RND 174
Cdd:PRK13652  109 LDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPeTYG 188


                  ....*....
gi 1447648657 175 TIVVVSTHD 183
Cdd:PRK13652  189 MTVIFSTHQ 197
PLN03073 PLN03073
ABC transporter F family; Provisional
 12-157 8.61e-12

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 63.34  E-value: 8.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidSMRWIFQNPHGVaqrTAIDHVSLPL 91
Cdd:PLN03073  518 YPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSA--KVRMAVFSQHHV---DGLDLSSNPL 592

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447648657  92 LA-----KGLPrreaEEQARTLMDRFNLT-RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDM 157
Cdd:PLN03073  593 LYmmrcfPGVP----EQKLRAHLGSFGVTgNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDL 660
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 21-183 8.68e-12

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 62.82  E-value: 8.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKST-------LL---GIIAGWTT---------PaEGQVTRQGIDSMRWIFQ------NP 75
Cdd:PRK09473   34 DLNFSLRAGETLGIVGESGSGKSQtafalmgLLaanGRIGGSATfngreilnlP-EKELNKLRAEQISMIFQdpmtslNP 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  76 HgvaQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFA---ELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:PRK09473  113 Y---MRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKMPEARKRMKMyphEFSGGMRQRVMIAMALLCRPKLLIADEPT 189

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1447648657 153 AQLDMHTAATVSESLSRIARN-DTIVVVSTHD 183
Cdd:PRK09473  190 TALDVTVQAQIMTLLNELKREfNTAIIMITHD 221
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 31-183 1.16e-11

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 62.04  E-value: 1.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  31 VYALTGPSGAGKSTLLGI-------IAGWTTPAEGQVTRQGIDSMR----------WIFQNPHGVAQrTAIDHVSLPLLA 93
Cdd:PRK14271   49 VTSLMGPTGSGKTTFLRTlnrmndkVSGYRYSGDVLLGGRSIFNYRdvlefrrrvgMLFQRPNPFPM-SIMDNVLAGVRA 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  94 -KGLPRREAEEQARTLMDRFNL-----TRVTDRRFaELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESL 167
Cdd:PRK14271  128 hKLVPRKEFRGVAQARLTEVGLwdavkDRLSDSPF-RLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFI 206

                         170
                  ....*....|....*.
gi 1447648657 168 SRIARNDTIVVVsTHD 183
Cdd:PRK14271  207 RSLADRLTVIIV-THN 221
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
3-156 1.28e-11

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 62.17  E-value: 1.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDSMR------------W 70
Cdd:PRK11650    4 LKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIW---IGGRVvnelepadrdiaM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 IFQN----PH-GVAQRTAIDhvslpLLAKGLPRRE----AEEQARTLmdrfNLTRVTDRRFAELSGGEAQRLMLARAFAA 141
Cdd:PRK11650   81 VFQNyalyPHmSVRENMAYG-----LKIRGMPKAEieerVAEAARIL----ELEPLLDRKPRELSGGQRQRVAMGRAIVR 151

                         170
                  ....*....|....*
gi 1447648657 142 QPSLMLVDEPTAQLD 156
Cdd:PRK11650  152 EPAVFLFDEPLSNLD 166
PLN03140 PLN03140
ABC transporter G family member; Provisional
 18-185 1.42e-11

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 62.56  E-value: 1.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA--EGQVTRQGIDSMRWIFQNPHGVAQRTAIDH----VSLPL 91
Cdd:PLN03140   895 LLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGyiEGDIRISGFPKKQETFARISGYCEQNDIHSpqvtVRESL 974

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   92 LAKG---LPRREAEEQARTLMDR-FNLTRVTDRRFA--------ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHT 159
Cdd:PLN03140   975 IYSAflrLPKEVSKEEKMMFVDEvMELVELDNLKDAivglpgvtGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARA 1054

                          170       180       190
                   ....*....|....*....|....*....|
gi 1447648657  160 AATVseslSRIARN--DT--IVVVSTHDPN 185
Cdd:PLN03140  1055 AAIV----MRTVRNtvDTgrTVVCTIHQPS 1080
cbiO PRK13646
energy-coupling factor transporter ATPase;
1-185 2.53e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 60.95  E-value: 2.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADG-PLLF---HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR------- 69
Cdd:PRK13646    1 MTIRFDNVSYTYQKGtPYEHqaiHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHktkdkyi 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 --------WIFQNPHgvAQRTAiDHVSLPLLAK----GLPRREAEEQARTLMDRFNLTR-VTDRRFAELSGGEAQRLMLA 136
Cdd:PRK13646   81 rpvrkrigMVFQFPE--SQLFE-DTVEREIIFGpknfKMNLDEVKNYAHRLLMDLGFSRdVMSQSPFQMSGGQMRKIAIV 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 137 RAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA--RNDTIVVVsTHDPN 185
Cdd:PRK13646  158 SILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtdENKTIILV-SHDMN 207
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
19-155 3.41e-11

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 60.28  E-value: 3.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW---------IFQNPHG--VAQRTAIDHv 87
Cdd:PRK11614   21 LHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWqtakimreaVAIVPEGrrVFSRMTVEE- 99

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447648657  88 SLPLLAKGLPRREAEEQARTLMDRFnlTRVTDRRF---AELSGGEAQRLMLARAFAAQPSLMLVDEPTAQL 155
Cdd:PRK11614  100 NLAMGGFFAERDQFQERIKWVYELF--PRLHERRIqraGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGL 168
cbiO PRK13641
energy-coupling factor transporter ATPase;
1-156 4.28e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 60.61  E-value: 4.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLL----FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-----------RQGI 65
Cdd:PRK13641    1 MSIKFENVDYIYSPGTPMekkgLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITiagyhitpetgNKNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  66 DSMR----WIFQNPHG-VAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAF 139
Cdd:PRK13641   81 KKLRkkvsLVFQFPEAqLFENTVLKDVEFGPKNFGFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVM 160

                         170
                  ....*....|....*..
gi 1447648657 140 AAQPSLMLVDEPTAQLD 156
Cdd:PRK13641  161 AYEPEILCLDEPAAGLD 177
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 14-180 5.35e-11

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 61.11  E-value: 5.35e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidSMRWifqnphgVAQRTAIDHVSLP--- 90
Cdd:TIGR00957  649 DLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG--SVAY-------VPQQAWIQNDSLReni 719

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   91 LLAKGL--PRREAEEQARTLMDRFNLTRVTDR-----RFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH----- 158
Cdd:TIGR00957  720 LFGKALneKYYQQVLEACALLPDLEILPSGDRteigeKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHvgkhi 799

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1447648657  159 --------------TAATVSESLSRIARNDTIVVVS 180
Cdd:TIGR00957  800 fehvigpegvlknkTRILVTHGISYLPQVDVIIVMS 835
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 3-180 5.39e-11

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 60.91  E-value: 5.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMRWI 71
Cdd:TIGR01193 474 IVINDVSYSYGYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSlkdidrhtlrqFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  72 FQNPHgVAQRTAIDHvslpLLAKGLPRREAEE--------QARTLMDRFNL---TRVTDRRFAeLSGGEAQRLMLARAFA 140
Cdd:TIGR01193 554 PQEPY-IFSGSILEN----LLLGAKENVSQDEiwaaceiaEIKDDIENMPLgyqTELSEEGSS-ISGGQKQRIALARALL 627

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 141 AQPSLMLVDEPTAQLDMHTAATVSESLSRIaRNDTIVVVS 180
Cdd:TIGR01193 628 TDSKVLILDESTSNLDTITEKKIVNNLLNL-QDKTIIFVA 666
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
96-182 5.41e-11

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 60.52  E-value: 5.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  96 LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDT 175
Cdd:NF000106  116 LSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGA 195


                  ....*..
gi 1447648657 176 IVVVSTH 182
Cdd:NF000106  196 TVLLTTQ 202
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 3-183 6.40e-11

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 60.52  E-value: 6.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADgPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-------------RQGIDSMR 69
Cdd:PRK11819  325 IEAENLSKSFGD-RLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKigetvklayvdqsRDALDPNK 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQNPHGVAqrtaiDHVSLpllakGlprrEAEEQARTLMDRFNLtRVTD--RRFAELSGGEAQRLMLARAFAAQPSLML 147
Cdd:PRK11819  404 TVWEEISGGL-----DIIKV-----G----NREIPSRAYVGRFNF-KGGDqqKKVGVLSGGERNRLHLAKTLKQGGNVLL 468

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1447648657 148 VDEPTAQLDMHTAATVSESLSRIArnDTIVVVStHD 183
Cdd:PRK11819  469 LDEPTNDLDVETLRALEEALLEFP--GCAVVIS-HD 501
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 22-194 6.92e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 60.80  E-value: 6.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   22 LTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID---SMRWIFQNPHGVAQR-------TAIDHVSLPL 91
Cdd:TIGR01257  949 LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDietNLDAVRQSLGMCPQHnilfhhlTVAEHILFYA 1028

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   92 LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIa 171
Cdd:TIGR01257 1029 QLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKY- 1107

                          170       180
                   ....*....|....*....|...
gi 1447648657  172 RNDTIVVVSTHDPNTRDACTDII 194
Cdd:TIGR01257 1108 RSGRTIIMSTHHMDEADLLGDRI 1130
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3-155 1.01e-10

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 59.80  E-value: 1.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYadGPL-LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW----------- 70
Cdd:PRK09700    6 ISMAGIGKSF--GPVhALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLdhklaaqlgig 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 -IFQnphgvaQRTAIDHVSL-------PLLAK---GLP---RREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLA 136
Cdd:PRK09700   84 iIYQ------ELSVIDELTVlenlyigRHLTKkvcGVNiidWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIA 157

                         170
                  ....*....|....*....
gi 1447648657 137 RAFAAQPSLMLVDEPTAQL 155
Cdd:PRK09700  158 KTLMLDAKVIIMDEPTSSL 176
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
15-182 1.39e-10

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 58.32  E-value: 1.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  15 GPLLFHdltasLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG-----IDSMRWIFQNPHGVAQRTAIDHVSL 89
Cdd:PRK13543   28 GPLDFH-----VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGktatrGDRSRFMAYLGHLPGLKADLSTLEN 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  90 PLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSR 169
Cdd:PRK13543  103 LHFLCGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISA 182

                         170
                  ....*....|...
gi 1447648657 170 IARNDTIVVVSTH 182
Cdd:PRK13543  183 HLRGGGAALVTTH 195
cbiO PRK13637
energy-coupling factor transporter ATPase;
29-178 1.62e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 58.91  E-value: 1.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  29 GHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------SMRWI-------FQNP-HGVAQRTAIDHVSLPLLAK 94
Cdd:PRK13637   33 GEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDitdkkvKLSDIrkkvglvFQYPeYQLFEETIEKDIAFGPINL 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQARTLMDRFNLTRVT--DRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD-------------MH- 158
Cdd:PRK13637  113 GLSEEEIENRVKRAMNIVGLDYEDykDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDpkgrdeilnkikeLHk 192

                         170       180
                  ....*....|....*....|....*
gi 1447648657 159 ----TAATVSESLSRIAR-NDTIVV 178
Cdd:PRK13637  193 eynmTIILVSHSMEDVAKlADRIIV 217
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 14-198 1.95e-10

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 57.48  E-value: 1.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGidSMR------WI----------FQNPHG 77
Cdd:cd03250    16 ETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG--SIAyvsqepWIqngtirenilFGKPFD 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 vAQR--TAID----HVSLPLLAKGLprreaeeqartlmdrfnLTRVTDRRFAeLSGGEAQRLMLARAFAAQPSLMLVDEP 151
Cdd:cd03250    94 -EERyeKVIKacalEPDLEILPDGD-----------------LTEIGEKGIN-LSGGQKQRISLARAVYSDADIYLLDDP 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 152 TAQLDMHTAATVSES--LSRIARNDTIVVVsTHDPNTRDACTDIIDLKN 198
Cdd:cd03250   155 LSAVDAHVGRHIFENciLGLLLNNKTRILV-THQLQLLPHADQIVVLDN 202
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 12-196 2.01e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 59.19  E-value: 2.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLFH-DLTasLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGVAQRTAIDHVS-- 88
Cdd:PRK11147   13 FSDAPLLDNaELH--IEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVARLQQDPPRNVEGTVYDFVAeg 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  89 LPLLAKGLPRR-------EAEEQARTL---------MDRFNL----TRVT----------DRRFAELSGGEAQRLMLARA 138
Cdd:PRK11147   91 IEEQAEYLKRYhdishlvETDPSEKNLnelaklqeqLDHHNLwqleNRINevlaqlgldpDAALSSLSGGWLRKAALGRA 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLsrIARNDTIVVVStHDPN-TRDACTDIIDL 196
Cdd:PRK11147  171 LVSNPDVLLLDEPTNHLDIETIEWLEGFL--KTFQGSIIFIS-HDRSfIRNMATRIVDL 226
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
3-182 2.11e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 58.56  E-value: 2.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADG-----PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR----W--- 70
Cdd:PRK13633    5 IKCKNVSYKYESNeesteKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDeenlWdir 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  71 -----IFQNPHGVAQRTAIDH-VSLPLLAKGLPRREAEEQARTLMDRFNLTRVtdRRFAE--LSGGEAQRLMLARAFAAQ 142
Cdd:PRK13633   85 nkagmVFQNPDNQIVATIVEEdVAFGPENLGIPPEEIRERVDESLKKVGMYEY--RRHAPhlLSGGQKQRVAIAGILAMR 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTI-VVVSTH 182
Cdd:PRK13633  163 PECIIFDEPTAMLDPSGRREVVNTIKELNKKYGItIILITH 203
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 3-182 3.56e-10

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 58.30  E-value: 3.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPL-LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRW----IFQNPHG 77
Cdd:PRK11160  339 LTLNNVSFTYPDQPQpVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYseaaLRQAISV 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 VAQRTAIDHVSLP---LLAKGlprREAEEQARTLMDRFNLTRVTD-------------RrfaELSGGEAQRLMLARAFAA 141
Cdd:PRK11160  419 VSQRVHLFSATLRdnlLLAAP---NASDEALIEVLQQVGLEKLLEddkglnawlgeggR---QLSGGEQRRLGIARALLH 492

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 142 QPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVsTH 182
Cdd:PRK11160  493 DAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMI-TH 532
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 2-195 3.65e-10

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 57.12  E-value: 3.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADG-PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-----------SMR 69
Cdd:cd03244     2 DIEFKNVSLRYRPNlPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDiskiglhdlrsRIS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQN-------------PHGVAQRTAIDHVslpLLAKGLprREAEEQARTLMDrfnlTRVTDRRfAELSGGEAQRLMLA 136
Cdd:cd03244    82 IIPQDpvlfsgtirsnldPFGEYSDEELWQA---LERVGL--KEFVESLPGGLD----TVVEEGG-ENLSVGQRQLLCLA 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657 137 RAFAAQPSLMLVDEPTAQLDMHTAATVSESLsRIARNDTIVVVSTHDPNTrdactdIID 195
Cdd:cd03244   152 RALLRKSKILVLDEATASVDPETDALIQKTI-REAFKDCTVLTIAHRLDT------IID 203
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 31-182 4.61e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 57.55  E-value: 4.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  31 VYALTGPSGAGKSTLLGIIAGWTTPAEGQVtrqgidSMRWIFQNPHGVAQRTAIDHVSLPL------------------- 91
Cdd:PRK13631   54 IYFIIGNSGSGKSTLVTHFNGLIKSKYGTI------QVGDIYIGDKKNNHELITNPYSKKIknfkelrrrvsmvfqfpey 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  92 ---------------LAKGLPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQL 155
Cdd:PRK13631  128 qlfkdtiekdimfgpVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGL 207

                         170       180
                  ....*....|....*....|....*..
gi 1447648657 156 DMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:PRK13631  208 DPKGEHEMMQLILDAKANNKTVFVITH 234
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 20-182 5.16e-10

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 56.96  E-value: 5.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGwtTPA----EGQVTRQGID---------SMRWI---FQNPHGVAQRTA 83
Cdd:CHL00131   24 KGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAykilEGDILFKGESildlepeerAHLGIflaFQYPIEIPGVSN 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  84 IDHVSLPLLAK----GLPRREAEEQARTLMDRFNLTRVtDRRFAE------LSGGEAQRLMLARAFAAQPSLMLVDEPTA 153
Cdd:CHL00131  102 ADFLRLAYNSKrkfqGLPELDPLEFLEIINEKLKLVGM-DPSFLSrnvnegFSGGEKKRNEILQMALLDSELAILDETDS 180

                         170       180
                  ....*....|....*....|....*....
gi 1447648657 154 QLDMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:CHL00131  181 GLDIDALKIIAEGINKLMTSENSIILITH 209
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 21-183 6.02e-10

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 57.82  E-value: 6.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQ-GIdSMRWIFQNPH-------------GVAQRTAI-- 84
Cdd:PRK11819   25 DISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPApGI-KVGYLPQEPQldpektvrenveeGVAEVKAAld 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  85 --DHVSLpllAKGLPRRE----AEEQAR--TLMDRFNLTRVtDRRF----------------AELSGGEAQRLMLARAFA 140
Cdd:PRK11819  104 rfNEIYA---AYAEPDADfdalAAEQGElqEIIDAADAWDL-DSQLeiamdalrcppwdakvTKLSGGERRRVALCRLLL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1447648657 141 AQPSLMLVDEPTAQLDMHTAATVSESLSRIArnDTIVVVsTHD 183
Cdd:PRK11819  180 EKPDMLLLDEPTNHLDAESVAWLEQFLHDYP--GTVVAV-THD 219
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 4-183 6.86e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 57.65  E-value: 6.86e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   4 DLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV---TRQGI---DSMRWIFqNPhg 77
Cdd:PRK11147  321 EMENVNYQIDGKQLV-KDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIhcgTKLEVayfDQHRAEL-DP-- 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 vaQRTAIDHvslplLAKGlpRREAEEQARtlmDRFNLTRVTDRRFA---------ELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK11147  397 --EKTVMDN-----LAEG--KQEVMVNGR---PRHVLGYLQDFLFHpkramtpvkALSGGERNRLLLARLFLKPSNLLIL 464

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 149 DEPTAQLDMHTAATVSESLSriARNDTIVVVStHD 183
Cdd:PRK11147  465 DEPTNDLDVETLELLEELLD--SYQGTVLLVS-HD 496
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
3-152 7.68e-10

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 57.44  E-value: 7.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwifqnphgVAQRT 82
Cdd:NF033858    2 ARLEGVSHRYGKTVAL-DDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGD-----------MADAR 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIDHVS-----LPL-LAK-------------------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLAR 137
Cdd:NF033858   70 HRRAVCpriayMPQgLGKnlyptlsvfenldffgrlfGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCC 149

                         170
                  ....*....|....*
gi 1447648657 138 AFAAQPSLMLVDEPT 152
Cdd:NF033858  150 ALIHDPDLLILDEPT 164
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 28-188 7.95e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 55.07  E-value: 7.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVtrqgidsmrwIFQNPhgvaqrtaidhvslpllakglprreaeEQART 107
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV----------IYIDG---------------------------EDILE 43

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  108 LMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES------LSRIARNDTIVVVST 181
Cdd:smart00382  44 EVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrllLLLKSEKNLTVILTT 123


                   ....*..
gi 1447648657  182 HDPNTRD 188
Cdd:smart00382 124 NDEKDLG 130
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 20-163 9.06e-10

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 57.02  E-value: 9.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKS-TLLGIIAGWTTPA----------EGQV-------TRQGI--DSMRWIFQNPHgva 79
Cdd:PRK15134   26 NDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypsgdirfHGESllhaseqTLRGVrgNKIAMIFQEPM--- 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  80 qrtaidhVSL-PL------------LAKGLPRREAEEQARTLMDRFNLtRVTDRRFA----ELSGGEAQRLMLARAFAAQ 142
Cdd:PRK15134  103 -------VSLnPLhtlekqlyevlsLHRGMRREAARGEILNCLDRVGI-RQAAKRLTdyphQLSGGERQRVMIAMALLTR 174

                         170       180
                  ....*....|....*....|.
gi 1447648657 143 PSLMLVDEPTAQLDMHTAATV 163
Cdd:PRK15134  175 PELLIADEPTTALDVSVQAQI 195
hmuV PRK13547
heme ABC transporter ATP-binding protein;
14-185 9.71e-10

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 56.37  E-value: 9.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA--------EGQVTRQG-----IDSMRWIFQN---PHG 77
Cdd:PRK13547   12 RHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGeplaaIDAPRLARLRavlPQA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  78 VAQRTAIDHVSLPLLAK-------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFA---------A 141
Cdd:PRK13547   92 AQPAFAFSAREIVLLGRypharraGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAqlwpphdaaQ 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447648657 142 QPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVS-THDPN 185
Cdd:PRK13547  172 PPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAiVHDPN 216
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 12-182 9.74e-10

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 55.73  E-value: 9.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT--RQGIDSMRWIFQNPHG-VAQRTAIDhvs 88
Cdd:PRK13540   11 YHDQPLL-QQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILfeRQSIKKDLCTYQKQLCfVGHRSGIN--- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  89 lPLLA------KGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAAT 162
Cdd:PRK13540   87 -PYLTlrenclYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLT 165

                         170       180
                  ....*....|....*....|
gi 1447648657 163 VSESLSRIARNDTIVVVSTH 182
Cdd:PRK13540  166 IITKIQEHRAKGGAVLLTSH 185
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 26-157 1.42e-09

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 56.79  E-value: 1.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  26 LMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG--IDS------------MRWIFQNPHGV--AQRTAIDHVSL 89
Cdd:PRK10261  347 LWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGqrIDTlspgklqalrrdIQFIFQDPYASldPRQTVGDSIME 426

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  90 PLLAKGL-PRREAEEQARTLMDRFNLTRVTDRRFA-ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDM 157
Cdd:PRK10261  427 PLRVHGLlPGKAAAARVAWLLERVGLLPEHAWRYPhEFSGGQRQRICIARALALNPKVIIADEAVSALDV 496
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 16-197 1.60e-09

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 54.29  E-value: 1.60e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  16 PLLFHDLTASLMPGHVYALTGPSGAGKSTLL---GIIAGwttpaegqvtrqgidsMRWIFQNPHGVAQRTAIdhvslpll 92
Cdd:cd03227     8 PSYFVPNDVTFGEGSLTIITGPNGSGKSTILdaiGLALG----------------GAQSATRRRSGVKAGCI-------- 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  93 akgLPRREAEeqartlmdrFNLTRVTdrrfaeLSGGEAQRLMLARAFA----AQPSLMLVDEPTAQLDMHTAATVSESLS 168
Cdd:cd03227    64 ---VAAVSAE---------LIFTRLQ------LSGGEKELSALALILAlaslKPRPLYILDEIDRGLDPRDGQALAEAIL 125

                         170       180
                  ....*....|....*....|....*....
gi 1447648657 169 RIARNDTIVVVSTHDPNTRDACTDIIDLK 197
Cdd:cd03227   126 EHLVKGAQVIVITHLPELAELADKLIHIK 154
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
29-183 1.75e-09

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 56.07  E-value: 1.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  29 GHVYALTGPSGAGKSTLLGIIAGwTTPAEGQVTrqgIDSMRW-----------------------IFQNPhgvaqRTAID 85
Cdd:COG4170    33 GEIRGLVGESGSGKSLIAKAICG-ITKDNWHVT---ADRFRWngidllklsprerrkiigreiamIFQEP-----SSCLD 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 HvSLPL---LAKGLPRREAEeqaRTLMDRFN---------LTRV--TDRRFA------ELSGGEAQRLMLARAFAAQPSL 145
Cdd:COG4170   104 P-SAKIgdqLIEAIPSWTFK---GKWWQRFKwrkkraielLHRVgiKDHKDImnsyphELTEGECQKVMIAMAIANQPRL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVStHD 183
Cdd:COG4170   180 LIADEPTNAMESTTQAQIFRLLARLNQLQgtSILLIS-HD 218
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 25-161 2.28e-09

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 56.17  E-value: 2.28e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSmrwIFQNP-HGVAQRTAIDHVSLPLLAK--------- 94
Cdd:PRK10762   26 NVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEV---TFNGPkSSQEAGIGIIHQELNLIPQltiaenifl 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447648657  95 ---------GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQL-DMHTAA 161
Cdd:PRK10762  103 grefvnrfgRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALtDTETES 179
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
21-193 2.46e-09

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 55.21  E-value: 2.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMrwIFQNPHGVAQRTAIDHVSLPLLAKGLPRRE 100
Cdd:PRK13546   42 DISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSV--IAISAGLSGQLTGIENIEFKMLCMGFKRKE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 101 AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAatvSESLSRI----ARNDTI 176
Cdd:PRK13546  120 IKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFA---QKCLDKIyefkEQNKTI 196

                         170
                  ....*....|....*..
gi 1447648657 177 VVVSTHDPNTRDACTDI 193
Cdd:PRK13546  197 FFVSHNLGQVRQFCTKI 213
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 18-180 3.09e-09

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 54.19  E-value: 3.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPA---EGQVTRQGIDSMrwIFQNPHgvaQRTAI----DHVSLP 90
Cdd:cd03233    22 ILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYK--EFAEKY---PGEIIyvseEDVHFP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  91 LLAKGlprreaeeqaRTLmdRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTA---ATVSESL 167
Cdd:cd03233    97 TLTVR----------ETL--DFALRCKGNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTAleiLKCIRTM 164

                         170
                  ....*....|...
gi 1447648657 168 SRIARNDTIVVVS 180
Cdd:cd03233   165 ADVLKTTTFVSLY 177
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 3-157 3.38e-09

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 55.67  E-value: 3.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRYADGPLlFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVtrqgidsmRWIFQNPHGV-AQR 81
Cdd:PRK15064  320 LEVENLTKGFDNGPL-FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV--------KWSENANIGYyAQD 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 TAIDhvslplLAKGLPRREAEEQARTLMDRFNLTRVTDRR--FAE---------LSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:PRK15064  391 HAYD------FENDLTLFDWMSQWRQEGDDEQAVRGTLGRllFSQddikksvkvLSGGEKGRMLFGKLMMQKPNVLVMDE 464


                  ....*..
gi 1447648657 151 PTAQLDM 157
Cdd:PRK15064  465 PTNHMDM 471
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 12-183 3.96e-09

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 54.66  E-value: 3.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  12 YADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWT-----TPAEGQVT---------RQGIDSMR----WIFQ 73
Cdd:PRK14258   16 YYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNeleseVRVEGRVEffnqniyerRVNLNRLRrqvsMVHP 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  74 NPHgVAQRTAIDHVSLPLLAKGL-PRREAE---EQARTLMDRFNLTRVTDRRFA-ELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK14258   96 KPN-LFPMSVYDNVAYGVKIVGWrPKLEIDdivESALKDADLWDEIKHKIHKSAlDLSGGQQQRLCIARALAVKPKVLLM 174

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 149 DEPTAQLDMHTAATVsESL--SRIARNDTIVVVSTHD 183
Cdd:PRK14258  175 DEPCFGLDPIASMKV-ESLiqSLRLRSELTMVIVSHN 210
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 18-183 1.13e-08

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 54.13  E-value: 1.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGVAQRTAIDHV---------- 87
Cdd:PRK15064   16 LFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNERLGKLRQDQFAFEEFTVLDTVimghtelwev 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 --------SLP--------------------------------LLAKGLPrreaEEQARTLMdrfnltrvtdrrfAELSG 127
Cdd:PRK15064   96 kqerdriyALPemseedgmkvadlevkfaemdgytaearagelLLGVGIP----EEQHYGLM-------------SEVAP 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 128 GEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSriARNDTIVVVStHD 183
Cdd:PRK15064  159 GWKLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLN--ERNSTMIIIS-HD 211
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 28-184 1.16e-08

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 53.96  E-value: 1.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   28 PGHVYALTGPSGAGKSTLLGIIA-----GWTTPAEGQVTRQGIDSMrwiFQNPHGVAQRTAIdHV-------SLPLLA-- 93
Cdd:TIGR00956  788 PGTLTALMGASGAGKTTLLNVLAervttGVITGGDRLVNGRPLDSS---FQRSIGYVQQQDL-HLptstvreSLRFSAyl 863

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   94 ---KGLPRREAEEQARTLMDRFNLTRVTDRRFAE----LSGGEAQRLMLARAFAAQPSLML-VDEPTAQLDMHTAATVSE 165
Cdd:TIGR00956  864 rqpKSVSKSEKMEYVEEVIKLLEMESYADAVVGVpgegLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICK 943

                          170
                   ....*....|....*....
gi 1447648657  166 SLSRIARNDTIVVVSTHDP 184
Cdd:TIGR00956  944 LMRKLADHGQAILCTIHQP 962
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 5-183 3.12e-08

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 52.75  E-value: 3.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRY---ADGPLL---------FHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSmrwif 72
Cdd:PRK15439  253 LELPGNRRqqaAGAPVLtvedltgegFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEI----- 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 qNPHGVAQRTAIDHVSLP--LLAKGL-----------------------PRREA---EEQARTLMDRFNLTRVTDRRfae 124
Cdd:PRK15439  328 -NALSTAQRLARGLVYLPedRQSSGLyldaplawnvcalthnrrgfwikPARENavlERYRRALNIKFNHAEQAART--- 403

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657 125 LSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:PRK15439  404 LSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSD 462
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 26-179 3.31e-08

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 52.71  E-value: 3.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  26 LMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQgidsmrwiFQNPHGVA------------QRTAIDHVSLPLLA 93
Cdd:PRK10938   26 LNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQ--------FSHITRLSfeqlqklvsdewQRNNTDMLSPGEDD 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  94 KGLPRRE-------AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES 166
Cdd:PRK10938   98 TGRTTAEiiqdevkDPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAEL 177

                         170
                  ....*....|....
gi 1447648657 167 LSRIARND-TIVVV 179
Cdd:PRK10938  178 LASLHQSGiTLVLV 191
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 2-156 3.44e-08

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 52.32  E-value: 3.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGwTTPA--EGQVT----RQGIDSMRW-IFQN 74
Cdd:PRK10938  260 RIVLNNGVVSYNDRPIL-HNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQgySNDLTlfgrRRGSGETIWdIKKH 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  75 PHGVAQRTAIDH-VSLPLL---------AKGLPRREAEEQ---ARTLMDRFNL-TRVTDRRFAELSGGEaQRLML-ARAF 139
Cdd:PRK10938  338 IGYVSSSLHLDYrVSTSVRnvilsgffdSIGIYQAVSDRQqklAQQWLDILGIdKRTADAPFHSLSWGQ-QRLALiVRAL 416

                         170
                  ....*....|....*..
gi 1447648657 140 AAQPSLMLVDEPTAQLD 156
Cdd:PRK10938  417 VKHPTLLILDEPLQGLD 433
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
1-182 3.56e-08

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 52.41  E-value: 3.56e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVGHRYADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGI-------DSMRWIF- 72
Cdd:PRK10789  314 LDVNIRQFTYPQTDHPAL-ENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIpltklqlDSWRSRLa 392

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  73 ---QNPHGVAQRTAIDhvslplLAKGLP---RREAEEQARTLM---DRFNL-----TRVTDRRFAeLSGGEAQRLMLARA 138
Cdd:PRK10789  393 vvsQTPFLFSDTVANN------IALGRPdatQQEIEHVARLASvhdDILRLpqgydTEVGERGVM-LSGGQKQRISIARA 465

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447648657 139 FAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTiVVVSTH 182
Cdd:PRK10789  466 LLLNAEILILDDALSAVDGRTEHQILHNLRQWGEGRT-VIISAH 508
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 95-183 3.60e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 52.01  E-value: 3.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQARTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARN 173
Cdd:PRK13651  135 GVSKEEAKKRAAKYIELVGLdESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ 214

                          90
                  ....*....|
gi 1447648657 174 DTIVVVSTHD 183
Cdd:PRK13651  215 GKTIILVTHD 224
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
3-179 3.60e-08

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 52.33  E-value: 3.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   3 VDLDHVGHRY--ADGPLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID-------SMR---- 69
Cdd:PRK11176  342 IEFRNVTFTYpgKEVPAL-RNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDlrdytlaSLRnqva 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 WIFQNPH----GVAQRTAI---DHVSlpllakglpRREAEEQART--LMDRFN-----LTRVTDRRFAELSGGEAQRLML 135
Cdd:PRK11176  421 LVSQNVHlfndTIANNIAYartEQYS---------REQIEEAARMayAMDFINkmdngLDTVIGENGVLLSGGQRQRIAI 491

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447648657 136 ARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVV 179
Cdd:PRK11176  492 ARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVI 535
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 33-196 3.89e-08

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 50.78  E-value: 3.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  33 ALTGPSGAGKSTLLgiiagwttpaegqvtrqgidsmrwifqnphgvaqRTAIDHVSLPLLAKGLPRREAE-----EQART 107
Cdd:cd03238    25 VVTGVSGSGKSTLV----------------------------------NEGLYASGKARLISFLPKFSRNklifiDQLQF 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 108 LMDrFNLTRVT-DRRFAELSGGEAQRLMLARAFAAQP--SLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDP 184
Cdd:cd03238    71 LID-VGLGYLTlGQKLSTLSGGELQRVKLASELFSEPpgTLFILDEPSTGLHQQDINQLLEVIKGLIDLGNTVILIEHNL 149

                         170
                  ....*....|..
gi 1447648657 185 NTRDACTDIIDL 196
Cdd:cd03238   150 DVLSSADWIIDF 161
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
11-157 4.21e-08

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 51.71  E-value: 4.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYADGplLFH--------DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDS--------------M 68
Cdd:PRK15112   15 RYRTG--WFRrqtveavkPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELL---IDDhplhfgdysyrsqrI 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  69 RWIFQNP-HGVAQRTAIDHV-SLPL-LAKGLPRREAEEQARTLMDRFNLTRVTDRRFAE-LSGGEAQRLMLARAFAAQPS 144
Cdd:PRK15112   90 RMIFQDPsTSLNPRQRISQIlDFPLrLNTDLEPEQREKQIIETLRQVGLLPDHASYYPHmLAPGQKQRLGLARALILRPK 169

                         170
                  ....*....|...
gi 1447648657 145 LMLVDEPTAQLDM 157
Cdd:PRK15112  170 VIIADEALASLDM 182
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
124-183 4.65e-08

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 51.73  E-value: 4.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447648657 124 ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARND--TIVVVStHD 183
Cdd:PRK15093  158 ELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNntTILLIS-HD 218
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
28-172 5.17e-08

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 51.84  E-value: 5.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQV-----------TRQGIDS-MRWIFQNPHGVAQRTAIDHVSLPLL-AK 94
Cdd:PRK11288   29 AGQVHALMGENGAGKSTLLKILSGNYQPDAGSIlidgqemrfasTTAALAAgVAIIYQELHLVPEMTVAENLYLGQLpHK 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 G--LPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLdmhtAATVSESLSRIAR 172
Cdd:PRK11288  109 GgiVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSL----SAREIEQLFRVIR 184
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 16-181 6.04e-08

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 51.40  E-value: 6.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  16 PLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDS----MRWIFQNP------HGVAQ----- 80
Cdd:cd03291    51 PVL-KNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRISfssqFSWIMPGTikeniiFGVSYdeyry 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPLLAKGLPrreaeEQARTLMDRFNLTrvtdrrfaeLSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTA 160
Cdd:cd03291   130 KSVVKACQLEEDITKFP-----EKDNTVLGEGGIT---------LSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTE 195

                         170       180
                  ....*....|....*....|..
gi 1447648657 161 ATVSES-LSRIARNDTIVVVST 181
Cdd:cd03291   196 KEIFEScVCKLMANKTRILVTS 217
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 16-181 8.39e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 51.45  E-value: 8.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   16 PLLfHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDS----MRWIFQnphGVAQRTAI-----DH 86
Cdd:TIGR01271  440 PVL-KNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISfspqTSWIMP---GTIKDNIIfglsyDE 515

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   87 VSLPLLAKGLPRRE-----AEEQARTLMDrfnlTRVTdrrfaeLSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAA 161
Cdd:TIGR01271  516 YRYTSVIKACQLEEdialfPEKDKTVLGE----GGIT------LSGGQRARISLARAVYKDADLYLLDSPFTHLDVVTEK 585

                          170       180
                   ....*....|....*....|.
gi 1447648657  162 TVSES-LSRIARNDTIVVVST 181
Cdd:TIGR01271  586 EIFEScLCKLMSNKTRILVTS 606
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 124-183 1.25e-07

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 50.51  E-value: 1.25e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 124 ELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTI-VVVSTHD 183
Cdd:PRK11022  153 QLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMaLVLITHD 213
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 21-183 1.90e-07

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 50.24  E-value: 1.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKS-TLLGII-----AGWTTPAEGQV----TRQGID---------------SMRWIFQNP 75
Cdd:PRK10261   34 NLSFSLQRGETLAIVGESGSGKSvTALALMrlleqAGGLVQCDKMLlrrrSRQVIElseqsaaqmrhvrgaDMAMIFQEP 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  76 hgvaqRTAIDHVsLPL---------LAKGLPRREAEEQARTLMDRFNLTR---VTDRRFAELSGGEAQRLMLARAFAAQP 143
Cdd:PRK10261  114 -----MTSLNPV-FTVgeqiaesirLHQGASREEAMVEAKRMLDQVRIPEaqtILSRYPHQLSGGMRQRVMIAMALSCRP 187

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1447648657 144 SLMLVDEPTAQLDMHTAATVSESLSRIARNDTI-VVVSTHD 183
Cdd:PRK10261  188 AVLIADEPTTALDVTIQAQILQLIKVLQKEMSMgVIFITHD 228
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 21-185 2.32e-07

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 49.10  E-value: 2.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRwiFQNPHGvaqrTAIDH-----VSLPLLAKG 95
Cdd:PRK13541   18 DLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINN--IAKPYC----TYIGHnlglkLEMTVFENL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  96 LPRREAEEQARTL---MDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIAR 172
Cdd:PRK13541   92 KFWSEIYNSAETLyaaIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLIVMKAN 171

                         170
                  ....*....|...
gi 1447648657 173 NDTIVVVSTHDPN 185
Cdd:PRK13541  172 SGGIVLLSSHLES 184
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 10-194 2.74e-07

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 48.72  E-value: 2.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  10 HRYADGPLLFHdlTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIdsmrwifqnphgvaqrtaidhvsl 89
Cdd:cd03222     8 KRYGVFFLLVE--LGVVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGI------------------------ 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  90 pllakglprreaeeqartlmdrfnlTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSR 169
Cdd:cd03222    62 -------------------------TPVYKPQYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRR 116

                         170       180
                  ....*....|....*....|....*.
gi 1447648657 170 -IARNDTIVVVSTHDPNTRDACTDII 194
Cdd:cd03222   117 lSEEGKKTALVVEHDLAVLDYLSDRI 142
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 2-184 3.16e-07

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 49.75  E-value: 3.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   2 RVDLDHVGHRYADGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAG-WTTPAeGQVTRQGIDSMRWIFQNPHgVAQ 80
Cdd:TIGR00954 451 GIKFENIPLVTPNGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGElWPVYG-GRLTKPAKGKLFYVPQRPY-MTL 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHVSLPLLAKGLPRREAEEQA-RTLMDRFNLTRVTDRRFA---------ELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:TIGR00954 529 GTLRDQIIYPDSSEDMKRRGLSDKDlEQILDNVQLTHILEREGGwsavqdwmdVLSGGEKQRIAMARLFYHKPQFAILDE 608

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1447648657 151 PTAQLdmhtAATVSESLSRIARNDTIVVVS-THDP 184
Cdd:TIGR00954 609 CTSAV----SVDVEGYMYRLCREFGITLFSvSHRK 639
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 29-150 4.50e-07

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 49.12  E-value: 4.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  29 GHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGvaQRTAIDHVSLPLLAKGLPRREAEEQARTL 108
Cdd:PRK13545   50 GEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAALIAISSGLNG--QLTGIENIELKGLMMGLTKEKIKEIIPEI 127

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1447648657 109 MDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:PRK13545  128 IEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDE 169
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 33-196 5.24e-07

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 48.41  E-value: 5.24e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  33 ALTGPSGAGKSTLlgiiAGWTTPAEGQvtRQGIDSMRWIFQNPHGVAQRTAIDHVslpllaKGLPRREAEEQART----- 107
Cdd:cd03270    25 VITGVSGSGKSSL----AFDTIYAEGQ--RRYVESLSAYARQFLGQMDKPDVDSI------EGLSPAIAIDQKTTsrnpr 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 108 --------LMDRFNL--------TRVT------------DRRFAELSGGEAQRLMLARAFAAQPS--LMLVDEPTAQLDM 157
Cdd:cd03270    93 stvgtvteIYDYLRLlfarvgirERLGflvdvglgyltlSRSAPTLSGGEAQRIRLATQIGSGLTgvLYVLDEPSIGLHP 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1447648657 158 HTAATVSESLSRI-ARNDTIVVVStHDPNTRDACTDIIDL 196
Cdd:cd03270   173 RDNDRLIETLKRLrDLGNTVLVVE-HDEDTIRAADHVIDI 211
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
21-198 5.26e-07

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 49.01  E-value: 5.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID------------SMRWIFQNPH--------GVAQ 80
Cdd:PRK09700  281 DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDisprspldavkkGMAYITESRRdngffpnfSIAQ 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  81 RTAIDHV--------SLPLLAKGLPRREAEEQARTLMDRfnlTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPT 152
Cdd:PRK09700  361 NMAISRSlkdggykgAMGLFHEVDEQRTAENQRELLALK---CHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPT 437

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1447648657 153 AQLDMHTAATVSESLSRIARN-DTIVVVSTHDPNTRDACTDIIDLKN 198
Cdd:PRK09700  438 RGIDVGAKAEIYKVMRQLADDgKVILMVSSELPEIITVCDRIAVFCE 484
PLN03073 PLN03073
ABC transporter F family; Provisional
 101-198 6.23e-07

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 49.09  E-value: 6.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 101 AEEQARTLMDRFNLT-RVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARndTIVVV 179
Cdd:PLN03073  320 AEARAASILAGLSFTpEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPK--TFIVV 397

                          90
                  ....*....|....*....
gi 1447648657 180 STHDPNTRDACTDIIDLKN 198
Cdd:PLN03073  398 SHAREFLNTVVTDILHLHG 416
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 28-155 6.27e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 48.96  E-value: 6.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  28 PGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGID--------------SMrwIFQNPHGVAQRTAIDHVSL---P 90
Cdd:PRK10982   23 PHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEidfksskealengiSM--VHQELNLVLQRSVMDNMWLgryP 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1447648657  91 LLAKGLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQL 155
Cdd:PRK10982  101 TKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSL 165
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 22-182 6.94e-07

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 48.25  E-value: 6.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  22 LTASLMPGHVYALTGPSGAGKSTLLGIIAGWT--TPAEGQVTRQGIDSMRW------------IFQNP---HGVAQR--- 81
Cdd:PRK09580   20 LNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELspedragegifmAFQYPveiPGVSNQffl 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  82 -TAIDHVslpllakglprREAEEQARtlMDRFNLTRVTDRRFAEL---------------SGGEAQRLMLARAFAAQPSL 145
Cdd:PRK09580  100 qTALNAV-----------RSYRGQEP--LDRFDFQDLMEEKIALLkmpedlltrsvnvgfSGGEKKRNDILQMAVLEPEL 166

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1447648657 146 MLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTH 182
Cdd:PRK09580  167 CILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTH 203
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 125-185 7.83e-07

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 48.87  E-value: 7.83e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657  125 LSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH------------------TAATVSESLSRIARNDTIVVVSTHDPN 185
Cdd:PTZ00265  1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNsekliektivdikdkadkTIITIAHRIASIKRSDKIVVFNNPDRT 1437
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
95-182 9.12e-07

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 48.58  E-value: 9.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDmhtaaTVS-----ESLSR 169
Cdd:NF033858  368 HLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVD-----PVArdmfwRLLIE 442

                          90
                  ....*....|....*
gi 1447648657 170 IARND--TIvVVSTH 182
Cdd:NF033858  443 LSREDgvTI-FISTH 456
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 17-195 1.07e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 48.24  E-value: 1.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  17 LLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGVAQrTAIDHV--------- 87
Cdd:PRK10636   15 VLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNWQLAWVNQETPALPQ-PALEYVidgdreyrq 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  88 ---------------SLPLLAKGLPRREA---EEQARTLMDRFNLTRVT-DRRFAELSGGEAQRLMLARAFAAQPSLMLV 148
Cdd:PRK10636   94 leaqlhdanerndghAIATIHGKLDAIDAwtiRSRAASLLHGLGFSNEQlERPVSDFSGGWRMRLNLAQALICRSDLLLL 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1447648657 149 DEPTAQLDMHTAATVSESLSriARNDTIVVVStHDpntRDACTDIID 195
Cdd:PRK10636  174 DEPTNHLDLDAVIWLEKWLK--SYQGTLILIS-HD---RDFLDPIVD 214
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 25-155 1.12e-06

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 48.12  E-value: 1.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  25 SLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMR------------WIFQNPHGVAQRTAIDHVSLpll 92
Cdd:PRK15439   33 TLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARltpakahqlgiyLVPQEPLLFPNLSVKENILF--- 109

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1447648657  93 akGLPRRE-AEEQARTLMDRFNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQL 155
Cdd:PRK15439  110 --GLPKRQaSMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTASL 171
cbiO PRK13645
energy-coupling factor transporter ATPase;
5-156 1.22e-06

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 47.70  E-value: 1.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   5 LDHVGHRYADG-PLLFHDL---TASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT------RQGIDSMR----- 69
Cdd:PRK13645    9 LDNVSYTYAKKtPFEFKALnntSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIvgdyaiPANLKKIKevkrl 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  70 -----WIFQNP-HGVAQRTAIDHVSLPLLAKGLPRREAEEQARTLMDRFNLTRVTDRRFA-ELSGGEAQRLMLARAFAAQ 142
Cdd:PRK13645   89 rkeigLVFQFPeYQLFQETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPEDYVKRSPfELSGGQKRRVALAGIIAMD 168

                         170
                  ....*....|....
gi 1447648657 143 PSLMLVDEPTAQLD 156
Cdd:PRK13645  169 GNTLVLDEPTGGLD 182
PLN03232 PLN03232
ABC transporter C family member; Provisional
 11-200 1.94e-06

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 47.66  E-value: 1.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   11 RYADG-PLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNphgVAQRTAIDHVSl 89
Cdd:PLN03232  1243 RYRPGlPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTD---LRRVLSIIPQS- 1318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   90 PLLAKGLPR--------------REAEEQA--RTLMDR--FNLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEP 151
Cdd:PLN03232  1319 PVLFSGTVRfnidpfsehndadlWEALERAhiKDVIDRnpFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEA 1398

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1447648657  152 TAQLDMHTAATVSESLSRIARNDTIVVVStHDPNTRDACTDIIDLKNYQ 200
Cdd:PLN03232  1399 TASVDVRTDSLIQRTIREEFKSCTMLVIA-HRLNTIIDCDKILVLSSGQ 1446
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 124-196 2.36e-06

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 46.45  E-value: 2.36e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 124 ELSGGEAQRLMLARAFAAQ---PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDIIDL 196
Cdd:cd03271   169 TLSGGEAQRIKLAKELSKRstgKTLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIEHNLDVIKCADWIIDL 244
PLN03232 PLN03232
ABC transporter C family member; Provisional
 21-166 4.39e-06

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 46.51  E-value: 4.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAE-GQVTRQG----IDSMRWIFQnphgvaqRTAIDHVslpLLAKG 95
Cdd:PLN03232   635 DINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAEtSSVVIRGsvayVPQVSWIFN-------ATVRENI---LFGSD 704

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   96 LprrEAEEQARTL--------MDRF---NLTRVTDRRfAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVS 164
Cdd:PLN03232   705 F---ESERYWRAIdvtalqhdLDLLpgrDLTEIGERG-VNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVF 780


                   ..
gi 1447648657  165 ES 166
Cdd:PLN03232   781 DS 782
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 125-194 1.02e-05

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 44.52  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 125 LSGGE------AQRLMLARAFAAQPSLMLVDEPTAQLDmhtAATVSESLSRIAR------NDTIVVVsTHDPNTRDACTD 192
Cdd:cd03240   116 CSGGEkvlaslIIRLALAETFGSNCGILALDEPTTNLD---EENIEESLAEIIEerksqkNFQLIVI-THDEELVDAADH 191


                  ..
gi 1447648657 193 II 194
Cdd:cd03240   192 IY 193
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 123-198 1.08e-05

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 45.41  E-value: 1.08e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447648657  123 AELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDT-IVVVSTHDPNTRDACTDIIDLKN 198
Cdd:PTZ00265   578 SKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENrITIIIAHRLSTIRYANTIFVLSN 654
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 21-184 1.10e-05

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 45.20  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAG-WTTPAEGQV--------TRQGIDSMRW-IFQNP-----HGVAQRTAID 85
Cdd:TIGR02633 278 DVSFSLRRGEILGVAGLVGAGRTELVQALFGaYPGKFEGNVfingkpvdIRNPAQAIRAgIAMVPedrkrHGIVPILGVG 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  86 H-VSLPLL----AKGLPRREAEEQA-RTLMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH 158
Cdd:TIGR02633 358 KnITLSVLksfcFKMRIDAAAELQIiGSAIQRLKVkTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVG 437

                         170       180
                  ....*....|....*....|....*..
gi 1447648657 159 TAATVSESLSRIARND-TIVVVSTHDP 184
Cdd:TIGR02633 438 AKYEIYKLINQLAQEGvAIIVVSSELA 464
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 14-182 1.35e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 44.90  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   14 DGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTpAEGQVTrqgIDSMRW------IFQNPHGVAQRTAIdhV 87
Cdd:TIGR01271 1230 AGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQ---IDGVSWnsvtlqTWRKAFGVIPQKVF--I 1303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   88 SLPLLAKGLPRRE----------AEEQA-RTLMDRF--NLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQ 154
Cdd:TIGR01271 1304 FSGTFRKNLDPYEqwsdeeiwkvAEEVGlKSVIEQFpdKLDFVLVDGGYVLSNGHKQLMCLARSILSKAKILLLDEPSAH 1383

                          170       180
                   ....*....|....*....|....*...
gi 1447648657  155 LDMHTAATVSESLSRIARNDTiVVVSTH 182
Cdd:TIGR01271 1384 LDPVTLQIIRKTLKQSFSNCT-VILSEH 1410
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 125-196 1.43e-05

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 45.00  E-value: 1.43e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1447648657 125 LSGGEAQRLMLARAFAAQ---PSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDIIDL 196
Cdd:TIGR00630 830 LSGGEAQRIKLAKELSKRstgRTLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEHNLDVIKTADYIIDL 904
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 16-182 2.09e-05

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 43.74  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  16 PLLFHdLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDsmrwIFQNP-HGVAQRTAIDhVSLPLLAK 94
Cdd:cd03288    35 PVLKH-VKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGID----ISKLPlHTLRSRLSII-LQDPILFS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 GLPRREAEEQARTLMDRF------------------NLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:cd03288   109 GSIRFNLDPECKCTDDRLwealeiaqlknmvkslpgGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASID 188

                         170       180
                  ....*....|....*....|....*.
gi 1447648657 157 MHTaATVSESLSRIARNDTIVVVSTH 182
Cdd:cd03288   189 MAT-ENILQKVVMTAFADRTVVTIAH 213
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
 31-184 6.25e-05

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 42.26  E-value: 6.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  31 VYALTGPSGAGKSTLLGII--AGWttpaeGQVTRQGIDSMRWIFQNPhgvAQRTAidHVSLPLLAKGLPRR-------EA 101
Cdd:cd03279    30 LFLICGPTGAGKSTILDAItyALY-----GKTPRYGRQENLRSVFAP---GEDTA--EVSFTFQLGGKKYRversrglDY 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 102 EEQARTLM------DRFnLTRVTdrrfAELSGGEAQRLMLARAFA----AQPS------LMLVDEPTAQLDMHTAATVSE 165
Cdd:cd03279   100 DQFTRIVLlpqgefDRF-LARPV----STLSGGETFLASLSLALAlsevLQNRggarleALFIDEGFGTLDPEALEAVAT 174

                         170
                  ....*....|....*....
gi 1447648657 166 SLSRIARNDTIVVVSTHDP 184
Cdd:cd03279   175 ALELIRTENRMVGVISHVE 193
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 21-182 8.82e-05

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 41.93  E-value: 8.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  21 DLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQGIDSMRWIFQNPHGVAQRTAIDHVSLPLLAK------ 94
Cdd:cd03290    19 NINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYSVAYAAQKPWLLNatveen 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  95 ---GLP----RREAEEQARTLMDRFNLTRVTDR-----RFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTA-A 161
Cdd:cd03290    99 itfGSPfnkqRYKAVTDACSLQPDIDLLPFGDQteigeRGINLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSdH 178

                         170       180
                  ....*....|....*....|...
gi 1447648657 162 TVSESLSRIARND--TIVVVsTH 182
Cdd:cd03290   179 LMQEGILKFLQDDkrTLVLV-TH 200
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1-180 9.11e-05

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 42.21  E-value: 9.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   1 MRVDLDHVghryaDGPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTrqgIDSMRWIFQNP----- 75
Cdd:PRK11288  256 VRLRLDGL-----KGPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVY---LDGKPIDIRSPrdair 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  76 ------------------HGVAQRTAID----HVSLPLLAKglPRREAEeQARTLMDRFNL-TRVTDRRFAELSGGEAQR 132
Cdd:PRK11288  328 agimlcpedrkaegiipvHSVADNINISarrhHLRAGCLIN--NRWEAE-NADRFIRSLNIkTPSREQLIMNLSGGNQQK 404

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447648657 133 LMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIA-RNDTIVVVS 180
Cdd:PRK11288  405 AILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAaQGVAVLFVS 453
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
125-196 1.05e-04

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 42.32  E-value: 1.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657 125 LSGGEAQRLMLARAFA---AQPSLMLVDEPTAQLDMHTAATVSESLSR-IARNDTIVVVStHDPntrD--ACTD-IIDL 196
Cdd:COG0178   827 LSGGEAQRVKLASELSkrsTGKTLYILDEPTTGLHFHDIRKLLEVLHRlVDKGNTVVVIE-HNL---DviKTADwIIDL 901
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 120-196 1.32e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 42.12  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  120 RRFAELSGGEAQRLMLARAFAA---QPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDIIDL 196
Cdd:PRK00635   805 RPLSSLSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNMHVVKVADYVLEL 884
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 20-156 1.79e-04

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 41.53  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  20 HDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVT-----------RQGIDS-MRWIFQNPHG---VAQRTAI 84
Cdd:PRK10762  269 NDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTldghevvtrspQDGLANgIVYISEDRKRdglVLGMSVK 348

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447648657  85 DHVSLPLLAK-----GLPRREAEEQART-LMDRFNL-TRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLD 156
Cdd:PRK10762  349 ENMSLTALRYfsragGSLKHADEQQAVSdFIRLFNIkTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVD 427
AAA_29 pfam13555
P-loop containing region of AAA domain;
19-46 1.93e-04

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 37.96  E-value: 1.93e-04
                          10        20
                  ....*....|....*....|....*...
gi 1447648657  19 FHDLTASLMPGHVYALTGPSGAGKSTLL 46
Cdd:pfam13555  12 FDGHTIPIDPRGNTLLTGPSGSGKSTLL 39
SbcC_Walker_B pfam13558
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ...
 115-169 2.30e-04

SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.


Pssm-ID: 463921 [Multi-domain]  Cd Length: 90  Bit Score: 38.76  E-value: 2.30e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447648657 115 TRVTDRRFAELSGGEAQRLM---LARAFAAQ----------PSLMLVDEPTAQLDMHTAATVSESLSR 169
Cdd:pfam13558  23 EVETYRRSGGLSGGEKQLLAylpLAAALAAQygsaegrppaPRLVFLDEAFAKLDEENIRTALELLRA 90
PLN03130 PLN03130
ABC transporter C family member; Provisional
 28-180 2.86e-04

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 41.26  E-value: 2.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   28 PGHVYALTGPSGAGKSTLLGIIAGWTTP-AEGQVTRQG----IDSMRWIFQ----------NPHGVAQR------TAIDH 86
Cdd:PLN03130   642 VGSLVAIVGSTGEGKTSLISAMLGELPPrSDASVVIRGtvayVPQVSWIFNatvrdnilfgSPFDPERYeraidvTALQH 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   87 vSLPLLAKGlprreaeeqartlmdrfNLTRVTDRRfAELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSES 166
Cdd:PLN03130   722 -DLDLLPGG-----------------DLTEIGERG-VNISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFDK 782

                          170
                   ....*....|....*
gi 1447648657  167 -LSRIARNDTIVVVS 180
Cdd:PLN03130   783 cIKDELRGKTRVLVT 797
YjeQ_EngC cd01854
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ...
 24-46 6.04e-04

Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.


Pssm-ID: 206747 [Multi-domain]  Cd Length: 211  Bit Score: 39.30  E-value: 6.04e-04
                          10        20
                  ....*....|....*....|...
gi 1447648657  24 ASLMPGHVYALTGPSGAGKSTLL 46
Cdd:cd01854    80 RELLKGKTSVLVGQSGVGKSTLL 102
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 11-182 6.71e-04

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 39.45  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  11 RYAD-GPLLFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTpAEGQVTrqgIDSMRW------IFQNPHGV-AQRT 82
Cdd:cd03289    11 KYTEgGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQ---IDGVSWnsvplqKWRKAFGViPQKV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657  83 AIdhVSLPLLAKGLPR---------REAEEQA-RTLMDRF--NLTRVTDRRFAELSGGEAQRLMLARAFAAQPSLMLVDE 150
Cdd:cd03289    87 FI--FSGTFRKNLDPYgkwsdeeiwKVAEEVGlKSVIEQFpgQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDE 164

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1447648657 151 PTAQLDMHTAATVSESLsRIARNDTIVVVSTH 182
Cdd:cd03289   165 PSAHLDPITYQVIRKTL-KQAFADCTVILSEH 195
PTZ00243 PTZ00243
ABC transporter; Provisional
 18-182 1.34e-03

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 38.99  E-value: 1.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   18 LFHDLTASLMPGHVYALTGPSGAGKSTLLGIIAGWTTPAEGQVTRQG----IDSMRWI----------FQNPHGVAQRTA 83
Cdd:PTZ00243   675 LLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERsiayVPQQAWImnatvrgnilFFDEEDAARLAD 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657   84 IDHVS-----LPLLAKGLPRREAEEQArtlmdrfnltrvtdrrfaELSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMH 158
Cdd:PTZ00243   755 AVRVSqleadLAQLGGGLETEIGEKGV------------------NLSGGQKARVSLARAVYANRDVYLLDDPLSALDAH 816

                          170       180
                   ....*....|....*....|....
gi 1447648657  159 TAATVSESLSRIARNDTIVVVSTH 182
Cdd:PTZ00243   817 VGERVVEECFLGALAGKTRVLATH 840
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 125-184 1.99e-03

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 38.17  E-value: 1.99e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447648657 125 LSGGEAQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDT-IVVVSTHDP 184
Cdd:PRK10982  392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKgIIIISSEMP 452
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 119-196 2.90e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 38.07  E-value: 2.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 119 DRRFAELSGGEAQRLMLARAFAAQPS--LMLVDEPTAQLDMHTAATVSESLSRIaRN--DTIVVVStHDPNTRDACTDII 194
Cdd:TIGR00630 483 SRAAGTLSGGEAQRIRLATQIGSGLTgvLYVLDEPSIGLHQRDNRRLINTLKRL-RDlgNTLIVVE-HDEDTIRAADYVI 560


                  ..
gi 1447648657 195 DL 196
Cdd:TIGR00630 561 DI 562
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 111-185 3.60e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 37.29  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447648657 111 RFNLTRVTDRRFAELSGGEAQRLMLA--RAFA-----AQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHD 183
Cdd:COG3593   149 SLRIEDGKELPLDRLGSGFQRLILLAllSALAelkraPANPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQVIITTHS 228


                  ..
gi 1447648657 184 PN 185
Cdd:COG3593   229 PH 230
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
125-194 4.78e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 37.35  E-value: 4.78e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447648657 125 LSGGE------AQRLMLARAFAAQPSLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDPNTRDACTDII 194
Cdd:PRK03918  789 LSGGErialglAFRLALSLYLAGNIPLLILDEPTPFLDEERRRKLVDIMERYLRKIPQVIIVSHDEELKDAADYVI 864
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 122-184 5.93e-03

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 36.60  E-value: 5.93e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447648657 122 FAELSGGEaQRL--MLARAFAAQP--SLMLVDEPTAQLDMHTAATVSESLSRIARNDTIVVVSTHDP 184
Cdd:pfam13304 234 AFELSDGT-KRLlaLLAALLSALPkgGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSP 299
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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