|
Name |
Accession |
Description |
Interval |
E-value |
| MoeA |
COG0303 |
Molybdopterin Mo-transferase (molybdopterin biosynthesis) [Coenzyme transport and metabolism]; ... |
1-401 |
6.98e-123 |
|
Molybdopterin Mo-transferase (molybdopterin biosynthesis) [Coenzyme transport and metabolism]; Molybdopterin Mo-transferase (molybdopterin biosynthesis) is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 440072 [Multi-domain] Cd Length: 401 Bit Score: 361.71 E-value: 6.98e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 1 MIDYDDALRRLLDAAKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTAGEPIAAGTEFDVQGGRAA-GD 79
Cdd:COG0303 1 MISVEEALALILAAVRPLGTETVPLAEALGRVLAEDVVAPRDVPPFDNSAMDGYAVRAADLAGANPVTLRVVGEIAAgSP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 80 GAAQATSG-AWEIMTGARMPDGLDAIVPIEQVDVLDTdadgrpsRIRLTAAVTHAQHLRRAGEDIAAATTFASPGALIDP 158
Cdd:COG0303 81 PPGPLGPGeAVRIMTGAPLPEGADAVVMQEDTEREGD-------RVTIRKPVAPGENIRRAGEDIAAGDVLLPAGTRLTP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 159 AMRMLCASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAI 238
Cdd:COG0303 154 ADLGLLASLGIAEVPVYRRPRVAILSTGDELV-EPGEPLGPGQIYDSNSYMLAALLREAGAEVVDLGIVPDDPEALRAAL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 239 ASLPPHV-VILSTGAVSMGRFDFVPEALARLGATTLFHKVRIRPGKPILAATLPsGALFFGLPGNPASTAVGLRFFVEPV 317
Cdd:COG0303 233 REALAEAdLVITSGGVSVGDYDLVKEALEELGAEVLFHKVAMKPGKPLAFGRLG-GKPVFGLPGNPVSALVTFELFVRPA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 318 LRAMLGLPPEVATFLPLRAA--YTKRVPLRMHLKARVALDaDARAGVEVLGGQESFRIRPLLDANAWAVVEPDVDVLDAG 395
Cdd:COG0303 312 LRKLAGLPPPPPPRVRARLAedLPKKPGRTEFLRVRLERD-DGELVVEPLGGQGSGLLSSLAEADGLIVLPEGVEGVEAG 390
|
....*.
gi 1444371852 396 ARVRVM 401
Cdd:COG0303 391 EEVEVL 396
|
|
| MoeA |
cd00887 |
MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor ... |
4-401 |
1.58e-121 |
|
MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.
Pssm-ID: 238452 [Multi-domain] Cd Length: 394 Bit Score: 357.96 E-value: 1.58e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 4 YDDALRRLLDAAKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALR---TAGEP--------IAAGTEFDVQ 72
Cdd:cd00887 1 VEAARELLLALAPPLGTETVPLLEALGRVLAEDVVAPIDLPPFDNSAMDGYAVRaadTAGASvtlrvvgeIPAGEPPDGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 73 GGRAAgdgaaqatsgAWEIMTGARMPDGLDAIVPIEQVDVLDtdadgrpSRIRLTAAVTHAQHLRRAGEDIAAATTFASP 152
Cdd:cd00887 81 LGPGE----------AVRIMTGAPLPEGADAVVMVEDTEEEG-------GRVTITKPVKPGQNIRRAGEDIKAGDVLLPA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 153 GALIDPAMRMLCASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDID 232
Cdd:cd00887 144 GTRLTPADIGLLASLGIAEVPVYRRPRVAIISTGDELV-EPGEPLAPGQIYDSNSYMLAALLRELGAEVVDLGIVPDDPE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 233 AFLEAIASLPPHV-VILSTGAVSMGRFDFVPEALARLGATTLFHKVRIRPGKPILAATLPsGALFFGLPGNPASTAVGLR 311
Cdd:cd00887 223 ALREALEEALEEAdVVITSGGVSVGDYDFVKEVLEELGGEVLFHGVAMKPGKPLAFGRLG-GKPVFGLPGNPVSALVTFE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 312 FFVEPVLRAMLGLPPEVATFLPLRAA--YTKRVPLRMHLKARVALDaDARAGVEVLGGQESFRIRPLLDANAWAVVEPDV 389
Cdd:cd00887 302 LFVRPALRKLQGAPEPEPPRVKARLAedLKSKPGRREFLRVRLERD-EGGLVVAPPGGQGSGLLSSLARADGLIVIPEGV 380
|
410
....*....|..
gi 1444371852 390 DVLDAGARVRVM 401
Cdd:cd00887 381 EGLEAGEEVEVL 392
|
|
| PRK14498 |
PRK14498 |
putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing ... |
1-400 |
2.54e-69 |
|
putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; Provisional
Pssm-ID: 237732 [Multi-domain] Cd Length: 633 Bit Score: 230.49 E-value: 2.54e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 1 MIDYDDALRRLLDA--AKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTA---------------GEPI 63
Cdd:PRK14498 9 LVSLEEAREILESLlsELPLGTEEVPLEEALGRVLAEDVYAPIDVPPFDRSAMDGYAVRAAdtfgaseanpvrlklGGEV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 64 AAGTEFDVQGGRAAgdgaaqatsgAWEIMTGARMPDGLDAIVPIEQVDVLDTDAdgrpsrIRLTAAVTHAQHLRRAGEDI 143
Cdd:PRK14498 89 HAGEAPDVEVEPGE----------AVEIATGAPIPRGADAVVMVEDTEEVDDDT------VEIYRPVAPGENVRPAGEDI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 144 AAATTFASPGALIDP-AMRMLcASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVV 222
Cdd:PRK14498 153 VAGELILPKGTRLTPrDIGAL-AAGGVAEVPVYKKPRVGIISTGDELV-EPGEPLKPGKIYDVNSYTLAAAVEEAGGEPV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 223 GARTVGDDIDAFLEAI-ASLPPHVVILSTGAVSMGRFDFVPEALARLGaTTLFHKVRIRPGKPILAATLpSGALFFGLPG 301
Cdd:PRK14498 231 RYGIVPDDEEELEAALrKALKECDLVLLSGGTSAGAGDVTYRVIEELG-EVLVHGVAIKPGKPTILGVI-GGKPVVGLPG 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 302 NPASTAVGLRFFVEPVLRAMLGLPPevatflPLRAAYTKRVPLRMHLKA------RVAL--DADARAGVEVLGGQESfrI 373
Cdd:PRK14498 309 YPVSALTIFEEFVAPLLRKLAGLPP------PERATVKARLARRVRSELgreefvPVSLgrVGDGYVAYPLSRGSGA--I 380
|
410 420
....*....|....*....|....*..
gi 1444371852 374 RPLLDANAWAVVEPDVDVLDAGARVRV 400
Cdd:PRK14498 381 TSLVRADGFIEIPANTEGLEAGEEVEV 407
|
|
| MoeA_N |
pfam03453 |
MoeA N-terminal region (domain I and II); This family contains two structural domains. One of ... |
23-168 |
1.23e-30 |
|
MoeA N-terminal region (domain I and II); This family contains two structural domains. One of these contains the conserved DGXA motif. This region is found in proteins involved in biosynthesis of molybdopterin cofactor however the exact molecular function of this region is uncertain.
Pssm-ID: 460923 [Multi-domain] Cd Length: 147 Bit Score: 114.97 E-value: 1.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 23 IDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRtagepIAAGTEFDVQGGRAAGDGAAQATSG--AWEIMTGARMPDG 100
Cdd:pfam03453 11 LEALDALGRVLAEDVVAPRDVPPFDRSAMDGYAVR-----AADGFGASEVNPIAAGEPPGPLLPGgeAVRIMTGAPLPEG 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1444371852 101 LDAIVPIEQVDvldtdaDGRPSRIRLTAAVTHAQHLRRAGEDIAAATTFASPGALIDPAMRMLCASVG 168
Cdd:pfam03453 86 ADAVVMVEDTE------EGGGRTVEIRAPVAPGENVRRAGEDIKAGEVVLPAGTRLTPAEIGLLASLG 147
|
|
| molyb_syn |
TIGR00177 |
molybdenum cofactor synthesis domain; The Drosophila protein cinnamon, the Arabidopsis protein ... |
178-316 |
9.40e-29 |
|
molybdenum cofactor synthesis domain; The Drosophila protein cinnamon, the Arabidopsis protein cnx1, and rat protein gephyrin each have one domain like MoeA and one like MoaB and Mog. These domains are, however, distantly related to each other, as captured by this model. Gephyrin is unusual in that it seems to be a tubulin-binding neuroprotein involved in the clustering of both blycine receptors and GABA receptors, rather than a protein of molybdenum cofactor biosynthesis.
Pssm-ID: 272944 [Multi-domain] Cd Length: 148 Bit Score: 109.71 E-value: 9.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 178 PRVALINTGRELVDdPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAIASLPPHV-VILSTGAVSMG 256
Cdd:TIGR00177 1 PRVAVISVGDELVE-GGQPLEPGQIYDSNGPLLAALLQEAGFNVVRLGIVPDDPEEIREILRKAVDEAdVVLTTGGTGVG 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 257 RFDFVPEALARLGA----------TTLFHKVRIRPGKPILAATLpSGALFFGLPGNPASTAVGLRFFVEP 316
Cdd:TIGR00177 80 PRDVTPEALEELGEkeipgfgefrMLSSLPVLSRPGKPATAGVR-GGTLIFNLPGNPVSALVTFEVLILP 148
|
|
| MoCF_biosynth |
smart00852 |
Probable molybdopterin binding domain; This domain is found a variety of proteins involved in ... |
181-313 |
9.99e-26 |
|
Probable molybdopterin binding domain; This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor. The domain is presumed to bind molybdopterin. The structure of this domain is known, and it forms an alpha/beta structure. In the known structure of Gephyrin this domain mediates trimerisation.
Pssm-ID: 214856 [Multi-domain] Cd Length: 138 Bit Score: 101.13 E-value: 9.99e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 181 ALINTGRELVDdprqpldAGQIRNSNGPFLAARLQAASADVVGARTVG--DDIDAFLEAIASLPPHV-VILSTGAVSMGR 257
Cdd:smart00852 1 AIISTGDELLS-------GGQIRDSNGPMLAALLRELGIEVVRVVVVGgpDDPEAIREALREALAEAdVVITTGGTGPGP 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1444371852 258 FDFVPEALARLGATTL-FHKVRIRPGKPILAATLPSGA--------LFFGLPGNPASTAVGLRFF 313
Cdd:smart00852 74 DDLTPEALAELGGRELlGHGVAMRPGGPPGPLANLSGTapgvrgkkPVFGLPGNPVAALVMFEEL 138
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MoeA |
COG0303 |
Molybdopterin Mo-transferase (molybdopterin biosynthesis) [Coenzyme transport and metabolism]; ... |
1-401 |
6.98e-123 |
|
Molybdopterin Mo-transferase (molybdopterin biosynthesis) [Coenzyme transport and metabolism]; Molybdopterin Mo-transferase (molybdopterin biosynthesis) is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 440072 [Multi-domain] Cd Length: 401 Bit Score: 361.71 E-value: 6.98e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 1 MIDYDDALRRLLDAAKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTAGEPIAAGTEFDVQGGRAA-GD 79
Cdd:COG0303 1 MISVEEALALILAAVRPLGTETVPLAEALGRVLAEDVVAPRDVPPFDNSAMDGYAVRAADLAGANPVTLRVVGEIAAgSP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 80 GAAQATSG-AWEIMTGARMPDGLDAIVPIEQVDVLDTdadgrpsRIRLTAAVTHAQHLRRAGEDIAAATTFASPGALIDP 158
Cdd:COG0303 81 PPGPLGPGeAVRIMTGAPLPEGADAVVMQEDTEREGD-------RVTIRKPVAPGENIRRAGEDIAAGDVLLPAGTRLTP 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 159 AMRMLCASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAI 238
Cdd:COG0303 154 ADLGLLASLGIAEVPVYRRPRVAILSTGDELV-EPGEPLGPGQIYDSNSYMLAALLREAGAEVVDLGIVPDDPEALRAAL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 239 ASLPPHV-VILSTGAVSMGRFDFVPEALARLGATTLFHKVRIRPGKPILAATLPsGALFFGLPGNPASTAVGLRFFVEPV 317
Cdd:COG0303 233 REALAEAdLVITSGGVSVGDYDLVKEALEELGAEVLFHKVAMKPGKPLAFGRLG-GKPVFGLPGNPVSALVTFELFVRPA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 318 LRAMLGLPPEVATFLPLRAA--YTKRVPLRMHLKARVALDaDARAGVEVLGGQESFRIRPLLDANAWAVVEPDVDVLDAG 395
Cdd:COG0303 312 LRKLAGLPPPPPPRVRARLAedLPKKPGRTEFLRVRLERD-DGELVVEPLGGQGSGLLSSLAEADGLIVLPEGVEGVEAG 390
|
....*.
gi 1444371852 396 ARVRVM 401
Cdd:COG0303 391 EEVEVL 396
|
|
| MoeA |
cd00887 |
MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor ... |
4-401 |
1.58e-121 |
|
MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.
Pssm-ID: 238452 [Multi-domain] Cd Length: 394 Bit Score: 357.96 E-value: 1.58e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 4 YDDALRRLLDAAKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALR---TAGEP--------IAAGTEFDVQ 72
Cdd:cd00887 1 VEAARELLLALAPPLGTETVPLLEALGRVLAEDVVAPIDLPPFDNSAMDGYAVRaadTAGASvtlrvvgeIPAGEPPDGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 73 GGRAAgdgaaqatsgAWEIMTGARMPDGLDAIVPIEQVDVLDtdadgrpSRIRLTAAVTHAQHLRRAGEDIAAATTFASP 152
Cdd:cd00887 81 LGPGE----------AVRIMTGAPLPEGADAVVMVEDTEEEG-------GRVTITKPVKPGQNIRRAGEDIKAGDVLLPA 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 153 GALIDPAMRMLCASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDID 232
Cdd:cd00887 144 GTRLTPADIGLLASLGIAEVPVYRRPRVAIISTGDELV-EPGEPLAPGQIYDSNSYMLAALLRELGAEVVDLGIVPDDPE 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 233 AFLEAIASLPPHV-VILSTGAVSMGRFDFVPEALARLGATTLFHKVRIRPGKPILAATLPsGALFFGLPGNPASTAVGLR 311
Cdd:cd00887 223 ALREALEEALEEAdVVITSGGVSVGDYDFVKEVLEELGGEVLFHGVAMKPGKPLAFGRLG-GKPVFGLPGNPVSALVTFE 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 312 FFVEPVLRAMLGLPPEVATFLPLRAA--YTKRVPLRMHLKARVALDaDARAGVEVLGGQESFRIRPLLDANAWAVVEPDV 389
Cdd:cd00887 302 LFVRPALRKLQGAPEPEPPRVKARLAedLKSKPGRREFLRVRLERD-EGGLVVAPPGGQGSGLLSSLARADGLIVIPEGV 380
|
410
....*....|..
gi 1444371852 390 DVLDAGARVRVM 401
Cdd:cd00887 381 EGLEAGEEVEVL 392
|
|
| PRK14498 |
PRK14498 |
putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing ... |
1-400 |
2.54e-69 |
|
putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; Provisional
Pssm-ID: 237732 [Multi-domain] Cd Length: 633 Bit Score: 230.49 E-value: 2.54e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 1 MIDYDDALRRLLDA--AKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTA---------------GEPI 63
Cdd:PRK14498 9 LVSLEEAREILESLlsELPLGTEEVPLEEALGRVLAEDVYAPIDVPPFDRSAMDGYAVRAAdtfgaseanpvrlklGGEV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 64 AAGTEFDVQGGRAAgdgaaqatsgAWEIMTGARMPDGLDAIVPIEQVDVLDTDAdgrpsrIRLTAAVTHAQHLRRAGEDI 143
Cdd:PRK14498 89 HAGEAPDVEVEPGE----------AVEIATGAPIPRGADAVVMVEDTEEVDDDT------VEIYRPVAPGENVRPAGEDI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 144 AAATTFASPGALIDP-AMRMLcASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVV 222
Cdd:PRK14498 153 VAGELILPKGTRLTPrDIGAL-AAGGVAEVPVYKKPRVGIISTGDELV-EPGEPLKPGKIYDVNSYTLAAAVEEAGGEPV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 223 GARTVGDDIDAFLEAI-ASLPPHVVILSTGAVSMGRFDFVPEALARLGaTTLFHKVRIRPGKPILAATLpSGALFFGLPG 301
Cdd:PRK14498 231 RYGIVPDDEEELEAALrKALKECDLVLLSGGTSAGAGDVTYRVIEELG-EVLVHGVAIKPGKPTILGVI-GGKPVVGLPG 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 302 NPASTAVGLRFFVEPVLRAMLGLPPevatflPLRAAYTKRVPLRMHLKA------RVAL--DADARAGVEVLGGQESfrI 373
Cdd:PRK14498 309 YPVSALTIFEEFVAPLLRKLAGLPP------PERATVKARLARRVRSELgreefvPVSLgrVGDGYVAYPLSRGSGA--I 380
|
410 420
....*....|....*....|....*..
gi 1444371852 374 RPLLDANAWAVVEPDVDVLDAGARVRV 400
Cdd:PRK14498 381 TSLVRADGFIEIPANTEGLEAGEEVEV 407
|
|
| PRK14491 |
PRK14491 |
putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoeA; ... |
5-400 |
3.32e-61 |
|
putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoeA; Provisional
Pssm-ID: 237729 [Multi-domain] Cd Length: 597 Bit Score: 207.93 E-value: 3.32e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 5 DDALRRLLDAAKPLPS-ERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTA----------GEpIAAGTEFDvqg 73
Cdd:PRK14491 202 SQGLDKILSLVTPVTEtEDVALDELDGRVLAQDVISPVNVPQHTNSAMDGYAFRSDdlepesytlvGE-VLAGHQYD--- 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 74 graagdgAAQATSGAWEIMTGARMPDGLDAIVPIEQVDVLDtdadgrpSRIRLTAAVTHAQHLRRAGEDIA-AATTFASP 152
Cdd:PRK14491 278 -------GTLQAGEAVRIMTGAPVPAGADTVVMRELATQDG-------DKVSFDGGIKAGQNVRLAGEDLAqGQVALAAG 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 153 GALIDPAMRMLcASVGIATVDVVRRPRVALINTGRElVDDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDID 232
Cdd:PRK14491 344 TRLSAPEQGLL-ASLGFAEVPVFRRPKVAVFSTGDE-VQAPGETLKPNCIYDSNRFTIKAMAKKLGCEVIDLGIIEDSEA 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 233 AFLEAIASLPPHV-VILSTGAVSMGRFDFVPEALARLGATTlFHKVRIRPGKPiLAATLPSGALFFGLPGNPASTAVGLR 311
Cdd:PRK14491 422 ALEATLEQAAAQAdVVISSGGVSVGDADYIKTALAKLGQID-FWRINMRPGRP-LAFGQIGDSPFFGLPGNPVAVMVSFL 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 312 FFVEPVLRAMLGLPPEVATFLPLRAAYTKRV-PLRM-HLKARVALDADARAGVEVLGGQESFRIRPLLDANAWAVVEPDV 389
Cdd:PRK14491 500 QFVEPALRKLAGEQNWQPLLFPAIADETLRSrQGRTeFSRGIYHLGADGRLHVRTTGKQGSGILSSMSEANCLIEIGPAA 579
|
410
....*....|.
gi 1444371852 390 DVLDAGARVRV 400
Cdd:PRK14491 580 ETVNAGETVTI 590
|
|
| PRK10680 |
PRK10680 |
molybdopterin biosynthesis protein MoeA; Provisional |
1-406 |
1.27e-56 |
|
molybdopterin biosynthesis protein MoeA; Provisional
Pssm-ID: 182643 [Multi-domain] Cd Length: 411 Bit Score: 191.46 E-value: 1.27e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 1 MIDYDDALRRLLDAAKPLP-SERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTA------GEPIA----AGTEF 69
Cdd:PRK10680 7 LMSLETALTEMLSRVTPLTaTETLPLVQCFGRITASDIVSPLDVPGFDNSAMDGYAVRLAdlasgqPLPVAgkafAGQPF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 70 DvqggraagdgaaqatsGAW------EIMTGARMPDGLDAIVPIEQVDVLDTDadgrpsrIRLTAAVTHAQHLRRAGEDI 143
Cdd:PRK10680 87 H----------------GEWpagtciRIMTGAPVPEGCEAVVMQEQTEQTDDG-------VRFTAEVRSGQNIRRRGEDI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 144 AAATTFASPGALIDPAMRMLCASVGIATVDVVRRPRVALINTGRELvDDPRQPLDAGQIRNSNGpfLAAR--LQAASADV 221
Cdd:PRK10680 144 SQGAVVFPAGTRLTTAELPVLASLGIAEVPVVRKVRVALFSTGDEL-QLPGQPLGDGQIYDTNR--LAVHlmLEQLGCEV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 222 VGARTVGDDID----AFLEAIASLPphvVILSTGAVSMGRFDFVPEALARLGATTlFHKVRIRPGKPILAATLPSgALFF 297
Cdd:PRK10680 221 INLGIIRDDPHalraAFIEADSQAD---VVISSGGVSVGEADYTKTILEELGEIA-FWKLAIKPGKPFAFGKLSN-SWFC 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 298 GLPGNPASTAVGLRFFVEPVLRAMLGlppEVATFLPLR-----AAYTKRVPLRMHLKARVA-LDADARAGVEVLGGQESF 371
Cdd:PRK10680 296 GLPGNPVSAALTFYQLVQPLLAKLSG---NTASGLPPRqrvrtASRLKKTPGRLDFQRGILqRNADGELEVTTTGHQGSH 372
|
410 420 430
....*....|....*....|....*....|....*
gi 1444371852 372 RIRPLLDANAWAVVEPDVDVLDAGARVRVMSRGHL 406
Cdd:PRK10680 373 IFSSFSLGNCFIVLERERGNVEVGEWVEVEPFNAL 407
|
|
| PRK14497 |
PRK14497 |
putative molybdopterin biosynthesis protein MoeA/unknown domain fusion protein; Provisional |
5-342 |
3.06e-47 |
|
putative molybdopterin biosynthesis protein MoeA/unknown domain fusion protein; Provisional
Pssm-ID: 172968 [Multi-domain] Cd Length: 546 Bit Score: 169.60 E-value: 3.06e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 5 DDALRRLLDAAKPLP-SERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTAGEP--------IAAGTEFDVQGGR 75
Cdd:PRK14497 14 DEAIKVFLSSLNFKPkIVKVEVKDSFGYVSAEDLMSPIDYPPFSRSTVDGYALKSSCTPgefkvidkIGIGEFKEIHIKE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 76 AAgdgaaqatsgAWEIMTGARMPDGLDAIVPIEQVDVLDTDadgrpsRIRLTAAVTHAQHLRRAGEDIAAATTFASPGAL 155
Cdd:PRK14497 94 CE----------AVEVDTGSMIPMGADAVIKVENTKVINGN------FIKIDKKINFGQNIGWIGSDIPKGSIILRKGEV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 156 IDPAMRMLCASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFL 235
Cdd:PRK14497 158 ISHEKIGLLASLGISSVKVYEKPKIYLIATGDELV-EPGNSLSPGKIYESNLHYLYSKLKSEGYKIVGLSLLSDDKESIK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 236 EAI-ASLPPHVVILSTGAVSMGRFDFVPEALARLGaTTLFHKVRIRPGKPILAATLpSGALFFGLPGNPASTAVGLRFFV 314
Cdd:PRK14497 237 NEIkRAISVADVLILTGGTSAGEKDFVHQAIRELG-NIIVHGLKIKPGKPTILGIV-DGKPVIGLPGNIVSTMVVLNMVI 314
|
330 340
....*....|....*....|....*...
gi 1444371852 315 EPVLRAMLGLPPEVATFLPLRAAYTKRV 342
Cdd:PRK14497 315 LEYLKSLYPSRKEILGLGKIKARLALRV 342
|
|
| PLN02699 |
PLN02699 |
Bifunctional molybdopterin adenylyltransferase/molybdopterin molybdenumtransferase |
1-398 |
4.03e-46 |
|
Bifunctional molybdopterin adenylyltransferase/molybdopterin molybdenumtransferase
Pssm-ID: 215376 [Multi-domain] Cd Length: 659 Bit Score: 168.07 E-value: 4.03e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 1 MIDYDDALRRLLDAAKPLPSERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRTAGEPiaagTEFDVQGGRAAGDG 80
Cdd:PLN02699 7 MISVEEALSIVLSVAARLSPVIVPLHEALGKVLAEDIRAPDPLPPYPASVKDGYAVVASDGP----GEYPVITESRAGND 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 81 AAQAT----SGAWeIMTGARMPDGLDAIVPIEQVDVLDTDADGRpSRIRLTAAVTHAQHLRRAGEDIAAATTFASPGALI 156
Cdd:PLN02699 83 GLGVTltpgTVAY-VTTGGPIPDGADAVVQVEDTEVVEDPLDGS-KRVRILSQASKGQDIRPVGCDIEKDAKVLKAGERL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 157 DPAMRMLCASVGIATVDVVRRPRVALINTGRELVDDPRQPLDAGQIRNSNGPFLAARLQAASADVVG---ARTVGDDIDA 233
Cdd:PLN02699 161 GASEIGLLATVGVTMVKVYPRPTVAILSTGDELVEPTTGTLGRGQIRDSNRAMLLAAAIQQQCKVVDlgiARDDEEELER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 234 FLEAIASLPPHvVILSTGAVSMGRFDFVPEALARLGaTTLFHKVRIRPGKPILAATLPSGA--------LFFGLPGNPAS 305
Cdd:PLN02699 241 ILDEAISSGVD-ILLTSGGVSMGDRDFVKPLLEKRG-TVYFSKVLMKPGKPLTFAEIDAKSapsnskkmLAFGLPGNPVS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 306 TAVGLRFFVEPVLRAMLGlppevatflplraaYTKRVPLRMHLKARVALDADA------RAGV---------------EV 364
Cdd:PLN02699 319 CLVCFNLFVVPAIRYLAG--------------WSNPHLLRVQARLREPIKLDPvrpefhRAIIrwklndgsgnpgfvaES 384
|
410 420 430
....*....|....*....|....*....|....
gi 1444371852 365 LGGQESFRIRPLLDANAWAVVEPDVDVLDAGARV 398
Cdd:PLN02699 385 TGHQMSSRLLSMKSANALLELPATGNVLSAGTSV 418
|
|
| PRK14690 |
PRK14690 |
molybdopterin biosynthesis protein MoeA; Provisional |
5-399 |
1.30e-31 |
|
molybdopterin biosynthesis protein MoeA; Provisional
Pssm-ID: 237789 [Multi-domain] Cd Length: 419 Bit Score: 124.64 E-value: 1.30e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 5 DDALRRLLDAAKPLPS-ERIDAADAIGRILAAPLTSAESLPPFDNSAMDGFAL---RTAGEPI--------AAGTEFDvq 72
Cdd:PRK14690 26 DTALDLLRARLGPVTDiKELDLSDALGHVLAHDAVALRSNPPQANSAVDGYGFagaAPEGAQVlpliegraAAGVPFS-- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 73 ggraagdgAAQATSGAWEIMTGARMPDGLDAIVpieqvdvLDTDADGRPSRIRLTAAVTHAQHLRRAGEDIAAATTFASP 152
Cdd:PRK14690 104 --------GRVPEGMALRILTGAALPEGVDTVV-------LEEDVAGDGHRIAFHGPLKMGANTRKAGEDVIAGDVALPA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 153 GALIDPAMRMLCASVGIATVDVVRRPRVALINTGRELVdDPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDID 232
Cdd:PRK14690 169 GRRLTPADLALLSAVGLTRVSVRRPLRVAVLSTGDELV-EPGALAEVGQIYDANRPMLLALARRWGHAPVDLGRVGDDRA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 233 AFLEAIASLPPHV-VILSTGAVSMGRFDFVPEALARLGATTLFhKVRIRPGKPiLAATLPSGALFFGLPGNPASTAVGLR 311
Cdd:PRK14690 248 ALAARLDRAAAEAdVILTSGGASAGDEDHVSALLREAGAMQSW-RIALKPGRP-LALGLWQGVPVFGLPGNPVAALVCTL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 312 FFVEPVLRAMLGLPPEVATFLPLRAAYTKR--VPLRMHLKARValdadaRAG-VEVLGGQESFRIRPLldanAWAvvEPD 388
Cdd:PRK14690 326 VFARPAMSLLAGEGWSEPQGFTVPAAFEKRkkPGRREYLRARL------RQGhAEVFRSEGSGRISGL----SWA--EGL 393
|
410
....*....|.
gi 1444371852 389 VDVLDAGARVR 399
Cdd:PRK14690 394 VELGDGARRIA 404
|
|
| MoeA_N |
pfam03453 |
MoeA N-terminal region (domain I and II); This family contains two structural domains. One of ... |
23-168 |
1.23e-30 |
|
MoeA N-terminal region (domain I and II); This family contains two structural domains. One of these contains the conserved DGXA motif. This region is found in proteins involved in biosynthesis of molybdopterin cofactor however the exact molecular function of this region is uncertain.
Pssm-ID: 460923 [Multi-domain] Cd Length: 147 Bit Score: 114.97 E-value: 1.23e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 23 IDAADAIGRILAAPLTSAESLPPFDNSAMDGFALRtagepIAAGTEFDVQGGRAAGDGAAQATSG--AWEIMTGARMPDG 100
Cdd:pfam03453 11 LEALDALGRVLAEDVVAPRDVPPFDRSAMDGYAVR-----AADGFGASEVNPIAAGEPPGPLLPGgeAVRIMTGAPLPEG 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1444371852 101 LDAIVPIEQVDvldtdaDGRPSRIRLTAAVTHAQHLRRAGEDIAAATTFASPGALIDPAMRMLCASVG 168
Cdd:pfam03453 86 ADAVVMVEDTE------EGGGRTVEIRAPVAPGENVRRAGEDIKAGEVVLPAGTRLTPAEIGLLASLG 147
|
|
| MoCF_biosynth |
pfam00994 |
Probable molybdopterin binding domain; This domain is found a variety of proteins involved in ... |
181-320 |
2.41e-30 |
|
Probable molybdopterin binding domain; This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor. The domain is presumed to bind molybdopterin. The structure of this domain is known, and it forms an alpha/beta structure. In the known structure of Gephyrin this domain mediates trimerization.
Pssm-ID: 425979 [Multi-domain] Cd Length: 143 Bit Score: 113.88 E-value: 2.41e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 181 ALINTGRELVddprqpldAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAIASLPPHV-VILSTGAVSMGRFD 259
Cdd:pfam00994 1 AIITTGDELL--------PGQIRDTNGPLLAALLREAGAEVIRYGIVPDDPEAIKEALRAAAEEAdVVITTGGTGPGPDD 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1444371852 260 FVPEALARLGATTL------FHKVRIRPGKPILAATLPS----GALFFGLPGNPASTAVGLRFFVEPVLRA 320
Cdd:pfam00994 73 VTPEALAELGGRELpgfeelFRGVSLKPGKPVGTAPGAIlsraGKTVFGLPGSPVAAKVMFELLLLPLLRH 143
|
|
| molyb_syn |
TIGR00177 |
molybdenum cofactor synthesis domain; The Drosophila protein cinnamon, the Arabidopsis protein ... |
178-316 |
9.40e-29 |
|
molybdenum cofactor synthesis domain; The Drosophila protein cinnamon, the Arabidopsis protein cnx1, and rat protein gephyrin each have one domain like MoeA and one like MoaB and Mog. These domains are, however, distantly related to each other, as captured by this model. Gephyrin is unusual in that it seems to be a tubulin-binding neuroprotein involved in the clustering of both blycine receptors and GABA receptors, rather than a protein of molybdenum cofactor biosynthesis.
Pssm-ID: 272944 [Multi-domain] Cd Length: 148 Bit Score: 109.71 E-value: 9.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 178 PRVALINTGRELVDdPRQPLDAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAIASLPPHV-VILSTGAVSMG 256
Cdd:TIGR00177 1 PRVAVISVGDELVE-GGQPLEPGQIYDSNGPLLAALLQEAGFNVVRLGIVPDDPEEIREILRKAVDEAdVVLTTGGTGVG 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 257 RFDFVPEALARLGA----------TTLFHKVRIRPGKPILAATLpSGALFFGLPGNPASTAVGLRFFVEP 316
Cdd:TIGR00177 80 PRDVTPEALEELGEkeipgfgefrMLSSLPVLSRPGKPATAGVR-GGTLIFNLPGNPVSALVTFEVLILP 148
|
|
| MoCF_biosynth |
smart00852 |
Probable molybdopterin binding domain; This domain is found a variety of proteins involved in ... |
181-313 |
9.99e-26 |
|
Probable molybdopterin binding domain; This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor. The domain is presumed to bind molybdopterin. The structure of this domain is known, and it forms an alpha/beta structure. In the known structure of Gephyrin this domain mediates trimerisation.
Pssm-ID: 214856 [Multi-domain] Cd Length: 138 Bit Score: 101.13 E-value: 9.99e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 181 ALINTGRELVDdprqpldAGQIRNSNGPFLAARLQAASADVVGARTVG--DDIDAFLEAIASLPPHV-VILSTGAVSMGR 257
Cdd:smart00852 1 AIISTGDELLS-------GGQIRDSNGPMLAALLRELGIEVVRVVVVGgpDDPEAIREALREALAEAdVVITTGGTGPGP 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1444371852 258 FDFVPEALARLGATTL-FHKVRIRPGKPILAATLPSGA--------LFFGLPGNPASTAVGLRFF 313
Cdd:smart00852 74 DDLTPEALAELGGRELlGHGVAMRPGGPPGPLANLSGTapgvrgkkPVFGLPGNPVAALVMFEEL 138
|
|
| MoCF_BD |
cd00758 |
MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of ... |
179-318 |
1.64e-17 |
|
MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin.
Pssm-ID: 238387 [Multi-domain] Cd Length: 133 Bit Score: 78.54 E-value: 1.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 179 RVALINTGRELVddprqpldAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAIASLPPHV-VILSTGAVSMGR 257
Cdd:cd00758 1 RVAIVTVSDELS--------QGQIEDTNGPALEALLEDLGCEVIYAGVVPDDADSIRAALIEASREAdLVLTTGGTGVGR 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1444371852 258 FDFVPEALARLGATTL-FHKVRIRPGKPILAATLpSGALFFGLPGNPASTAVGLRFFVEPVL 318
Cdd:cd00758 73 RDVTPEALAELGEREAhGKGVALAPGSRTAFGII-GKVLIINLPGSPKSALTTFEALVLPAL 133
|
|
| MoeA_like |
cd03522 |
MoeA_like. This domain is similar to a domain found in a variety of proteins involved in ... |
123-301 |
1.41e-06 |
|
MoeA_like. This domain is similar to a domain found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. There this domain is presumed to bind molybdopterin. The exact function of this subgroup is unknown.
Pssm-ID: 239599 Cd Length: 312 Bit Score: 49.85 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 123 RIRLTAAVTHA--QHLRRAGEDIAAATT----FASPGALIDpAMRMLCASVGIATVDVVRRPRVALINTGRELvddprqp 196
Cdd:cd03522 100 ALNAIDAITLAtlHNNTPVEAGQMVATVkiipLAVPEALVE-RAEALARDGPLLRVAPFRPLRVGLIVTGSEV------- 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 197 lDAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAIASLPPH--VVILSTGAVSMGRFDFVPEALARLGATTLF 274
Cdd:cd03522 172 -YGGRIEDKFGPVLRARLAALGVELVEQVIVPHDEAAIAAAIAEALEAgaELLILTGGASVDPDDVTPAAIRAAGGEVIR 250
|
170 180
....*....|....*....|....*..
gi 1444371852 275 HKVRIRPGKPILAATLpSGALFFGLPG 301
Cdd:cd03522 251 YGMPVDPGNLLLLGYL-GGVPVIGLPG 276
|
|
| MoeA_C |
pfam03454 |
MoeA C-terminal region (domain IV); This domain is found in proteins involved in biosynthesis ... |
332-401 |
1.32e-05 |
|
MoeA C-terminal region (domain IV); This domain is found in proteins involved in biosynthesis of molybdopterin cofactor however the exact molecular function of this domain is uncertain. The structure of this domain is known and forms an incomplete beta barrel.
Pssm-ID: 460924 [Multi-domain] Cd Length: 72 Bit Score: 42.98 E-value: 1.32e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 332 LPLRAAYTKRVPLRMHLKARVAlDADARAGVEVLGGQESFRIRPLLDANAWAVVEPDVDVLDAGARVRVM 401
Cdd:pfam03454 2 ARLARDLKSDPGRREFVRVRLH-EEDGRYYAEPIGKQGSGMLSSLAEANGLIVVPEGTEGLEAGEEVEVI 70
|
|
| cinA |
cd00885 |
Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon ... |
179-315 |
1.57e-05 |
|
Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, where the domain is presumed to bind molybdopterin.
Pssm-ID: 238450 [Multi-domain] Cd Length: 170 Bit Score: 45.17 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1444371852 179 RVALINTGRELVddprqpldAGQIRNSNGPFLAARLQAASADVVGARTVGDDIDAFLEAIASLPPHV-VILSTG------ 251
Cdd:cd00885 1 TAEIIAIGDELL--------SGQIVDTNAAFLAKELAELGIEVYRVTVVGDDEDRIAEALRRASERAdLVITTGglgpth 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1444371852 252 ------AVSM--GR---FDfvPEALARLGAttlFHKVRIRPGKP--ILAATLPSGALFfgLPgNPASTAVGlrFFVE 315
Cdd:cd00885 73 ddltreAVAKafGRplvLD--EEALERIEA---RFARRGREMTEanLKQAMLPEGATL--LP-NPVGTAPG--FSVE 139
|
|
| |
