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Conserved domains on  [gi|1407361710|gb|AWV98725.1|]
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hypothetical protein DJ013_11295 [Arcticibacterium luteifluviistationis]

Protein Classification

CHRD domain-containing protein( domain architecture ID 10538485)

CHRD domain-containing protein; CHRD is a domain found in chordin, an inhibitor of bone morphogenetic proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 25-133 9.15e-24

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


:

Pssm-ID: 462167  Cd Length: 118  Bit Score: 90.62  E-value: 9.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1407361710  25 SSTMNGGNEVPP-VETKGSGSLTGTYNARTNQITINASYSNLAaPPTGSHLHKAPAGANGSAIIFL------NATSGTIS 97
Cdd:pfam07452   2 SALLTGAQEVPPpVTTGAGGTAVLTLDDTENTLHYTLTFSGLS-VPTAAHIHAGAAGFNGPVVVPLeggprkTTLLAVPE 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1407361710  98 GTFTVAETDEPDLIA--GNVYINLHTNSFPGGEIRGQL 133
Cdd:pfam07452  81 GLATLTAAQLAALLAqqGELYVNVHTEGNPGGEIRGQI 118
 
Name Accession Description Interval E-value
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 25-133 9.15e-24

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


Pssm-ID: 462167  Cd Length: 118  Bit Score: 90.62  E-value: 9.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1407361710  25 SSTMNGGNEVPP-VETKGSGSLTGTYNARTNQITINASYSNLAaPPTGSHLHKAPAGANGSAIIFL------NATSGTIS 97
Cdd:pfam07452   2 SALLTGAQEVPPpVTTGAGGTAVLTLDDTENTLHYTLTFSGLS-VPTAAHIHAGAAGFNGPVVVPLeggprkTTLLAVPE 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1407361710  98 GTFTVAETDEPDLIA--GNVYINLHTNSFPGGEIRGQL 133
Cdd:pfam07452  81 GLATLTAAQLAALLAqqGELYVNVHTEGNPGGEIRGQI 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
25-134 3.08e-20

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 81.24  E-value: 3.08e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1407361710   25 SSTMNGGNEVPPVETKGSGSLTGTYNARTNqITINASYSNLAAPPTGSHLHKAPAGANGSAIIFL----NATSGTISGTF 100
Cdd:smart00754   4 SALLTGSQEVPPVNTGAVGGAWFTLDDDGS-LHYQVTLSGLSGPETAAHIHEGEIGTNGPVVRIPlpnpTSREGPFAGSV 82

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1407361710  101 TVAETDE-PDLIAGNVYINLHTNSFPGGEIRGQLA 134
Cdd:smart00754  83 KTLTDEElRQLLAGNLYVNVHTKANPGGEIRGQVA 117
 
Name Accession Description Interval E-value
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 25-133 9.15e-24

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


Pssm-ID: 462167  Cd Length: 118  Bit Score: 90.62  E-value: 9.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1407361710  25 SSTMNGGNEVPP-VETKGSGSLTGTYNARTNQITINASYSNLAaPPTGSHLHKAPAGANGSAIIFL------NATSGTIS 97
Cdd:pfam07452   2 SALLTGAQEVPPpVTTGAGGTAVLTLDDTENTLHYTLTFSGLS-VPTAAHIHAGAAGFNGPVVVPLeggprkTTLLAVPE 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1407361710  98 GTFTVAETDEPDLIA--GNVYINLHTNSFPGGEIRGQL 133
Cdd:pfam07452  81 GLATLTAAQLAALLAqqGELYVNVHTEGNPGGEIRGQI 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
25-134 3.08e-20

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 81.24  E-value: 3.08e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1407361710   25 SSTMNGGNEVPPVETKGSGSLTGTYNARTNqITINASYSNLAAPPTGSHLHKAPAGANGSAIIFL----NATSGTISGTF 100
Cdd:smart00754   4 SALLTGSQEVPPVNTGAVGGAWFTLDDDGS-LHYQVTLSGLSGPETAAHIHEGEIGTNGPVVRIPlpnpTSREGPFAGSV 82

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1407361710  101 TVAETDE-PDLIAGNVYINLHTNSFPGGEIRGQLA 134
Cdd:smart00754  83 KTLTDEElRQLLAGNLYVNVHTKANPGGEIRGQVA 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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