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Conserved domains on  [gi|1307934063|gb|AUE21426|]
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Permease protein of ABC transporter system for sugars [Bifidobacterium breve]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
15-320 3.79e-77

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 237.73  E-value: 3.79e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  15 RAAAKPKRSGAQKRENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFFRqvtegggaYGGGELVNKFVGFQNFQYVITSGN 94
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTD--------WNLLGPPPEFVGLDNYARLFTDPR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  95 FWSGVGRVLVYTLIQVPIMIIAALALAIVIDSfVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQISPIVKGLAAIGV 174
Cdd:COG1175    74 FWNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 175 -NVDFF-NKNIVLGSMANITTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVG 252
Cdd:COG1175   153 ePINWLgDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIG 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1307934063 253 TIQLFNEPQIMSTADPGISkSYTPMMMAMSTsqgSITPSGDGPASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:COG1175   233 ALQVFDLVYVLTGGGPGNS-TTTLVLYIYQT---AFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
15-320 3.79e-77

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 237.73  E-value: 3.79e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  15 RAAAKPKRSGAQKRENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFFRqvtegggaYGGGELVNKFVGFQNFQYVITSGN 94
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTD--------WNLLGPPPEFVGLDNYARLFTDPR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  95 FWSGVGRVLVYTLIQVPIMIIAALALAIVIDSfVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQISPIVKGLAAIGV 174
Cdd:COG1175    74 FWNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 175 -NVDFF-NKNIVLGSMANITTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVG 252
Cdd:COG1175   153 ePINWLgDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIG 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1307934063 253 TIQLFNEPQIMSTADPGISkSYTPMMMAMSTsqgSITPSGDGPASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:COG1175   233 ALQVFDLVYVLTGGGPGNS-TTTLVLYIYQT---AFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
malF PRK10999
maltose ABC transporter permease MalF;
80-236 1.43e-14

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 74.23  E-value: 1.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  80 FVGFQNFQYVITSGNFWSGVGRVLVYTLIQVPIMIIAALALAIVIDSFV----VKHVTGFRLGYFLPYAIPGVVASIIWV 155
Cdd:PRK10999  264 TIGWKNFTRVFTDEGIQKPFIAIFIWTVVFSLLTVVLTVAVGMVLACLVqweaLKGKAVYRVLLILPYAVPSFISILIFK 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 156 YLYN---GQISPIVKGLaaIGVNVDFFNKNIVLGSMANI-TTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIAT 231
Cdd:PRK10999  344 GLFNqsfGEINMMLSAL--FGIKPAWFSDPTLAKTMILIvNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFF 421


                  ....*
gi 1307934063 232 KIKLP 236
Cdd:PRK10999  422 KITLP 426
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 191-321 1.70e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.15  E-value: 1.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 191 ITTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNEPQIMsTADPGI 270
Cdd:pfam00528  58 LALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL-GSWPGL 136

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1307934063 271 SksytpmMMAMSTSQGSITPSGDGPASAIAIVMALIAGVLAVLYTLAERKV 321
Cdd:pfam00528 137 G------LLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 34-262 1.72e-09

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 58.54  E-value: 1.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  34 WAFMAPFAVLFAFVFILPIIWAIYSSFFRQVTEgggaygggelvnkFVGFQNFQYVITSGNFWSGVGRVLVYTLIQVPIM 113
Cdd:TIGR03262   4 RLLLAGMILALLLFLLLPLLALLTKSVYDSDGD-------------FIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 114 IIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQisPIVKGLAAIGVNVDFFNknIVLGSmaniTT 193
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQ--GLLKGLLGGFSIYGFWG--IVIGE----VF 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1307934063 194 WTFTgYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNEPQI 262
Cdd:TIGR03262 143 YTFP-HALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 103-257 8.39e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 51.51  E-value: 8.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 103 LVYTLIQVPIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYngqispivKGLAAIGVNVDFFNKN 182
Cdd:cd06261     5 LLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF--------GVLLGWGILPGLGLPA 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1307934063 183 IVLGSManittwTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLF 257
Cdd:cd06261    77 LILALL------LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
15-320 3.79e-77

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 237.73  E-value: 3.79e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  15 RAAAKPKRSGAQKRENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFFRqvtegggaYGGGELVNKFVGFQNFQYVITSGN 94
Cdd:COG1175     2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTD--------WNLLGPPPEFVGLDNYARLFTDPR 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  95 FWSGVGRVLVYTLIQVPIMIIAALALAIVIDSfVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQISPIVKGLAAIGV 174
Cdd:COG1175    74 FWNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 175 -NVDFF-NKNIVLGSMANITTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVG 252
Cdd:COG1175   153 ePINWLgDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIG 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1307934063 253 TIQLFNEPQIMSTADPGISkSYTPMMMAMSTsqgSITPSGDGPASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:COG1175   233 ALQVFDLVYVLTGGGPGNS-TTTLVLYIYQT---AFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 6-267 6.56e-24

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 99.39  E-value: 6.56e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063   6 TQAKGKAPRRAAAKPKRSGAQKRENRTGWAFMAPFAVLFAFVFILPIIWAIYS----SFFRQVTEgggaygggelvNKFV 81
Cdd:COG4209     2 STTAAKAKRKKKKRKKSFLKRLKRDWQLYLMLLPGLIYLLIFSYLPMYGIVIAfkdyNPFKGIFG-----------SPWV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  82 GFQNFQYVITSGNFWSGVGRVLVYTLIQVPIMIIAALALAIVIDSFVVKHvtgFRLGY----FLPYAIPGVVASIIWVYL 157
Cdd:COG4209    71 GLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILALLLNELRSKR---FKKTVqtisYLPHFLSWVVVAGIVYQF 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 158 YNGQISPIVKGLAAIGVN-VDFFNKN-----IVLGSmaniTTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIAT 231
Cdd:COG4209   148 LSPDTGLVNQLLRALGGEpINFLTEPkyfrpIYVFS----GIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIW 223

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1307934063 232 KIKLPNVRGAALLAMLLSI-----VGT--IQLFNEPQIMSTAD 267
Cdd:COG4209   224 HITLPGIRPTIVILLILNIgnilnVGFeqIYLLYNPLNYSTSD 266
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 28-323 1.41e-17

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 81.35  E-value: 1.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  28 RENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFFRQVTEGGGAYGggelvnkfVGFQNFQYVITSGNFWSGVGRVLVYTL 107
Cdd:COG1176     6 RRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPG--------FTLENYARLFTDPLYLKVLLRTLWIAL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 108 IQVPIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYL--YNGQISPIVKGLAAIGVNVDFFNKN--I 183
Cdd:COG1176    78 LTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLlgRNGLLNSLLLALGLIDEPLRLLYTEfaV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 184 VLGSmanitTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNEPQIM 263
Cdd:COG1176   158 VIGL-----VYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALL 232

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1307934063 264 STADpgisksytPMMMAMSTSQgSITPSGDGP-ASAIAIVMALIAGVLAVLYTLAERKVNE 323
Cdd:COG1176   233 GGGK--------VLMIGNLIYQ-QFLSALNWPlAAALAVVLLLIVLLVLLLYLRLLRRRRL 284
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
10-254 8.29e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 74.81  E-value: 8.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  10 GKAPRRAAAKPKRSGAQKRENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFfrqvtegggayggGELVNKFVGFQNFQYV 89
Cdd:COG1178   264 RRRRYATVGGRARRPRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSL-------------TKALDDNLTLDNYRFV 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  90 ITSGNFWSGVGRVLVYTLIQVPIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQISPIVKGL 169
Cdd:COG1178   331 LLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLLLYGT 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 170 AAIgvnvdffnknIVLGSMAnittwTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLS 249
Cdd:COG1178   411 LAI----------LVLAYVV-----RFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLV 475


                  ....*
gi 1307934063 250 IVGTI 254
Cdd:COG1178   476 FVTSM 480
malF PRK10999
maltose ABC transporter permease MalF;
80-236 1.43e-14

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 74.23  E-value: 1.43e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  80 FVGFQNFQYVITSGNFWSGVGRVLVYTLIQVPIMIIAALALAIVIDSFV----VKHVTGFRLGYFLPYAIPGVVASIIWV 155
Cdd:PRK10999  264 TIGWKNFTRVFTDEGIQKPFIAIFIWTVVFSLLTVVLTVAVGMVLACLVqweaLKGKAVYRVLLILPYAVPSFISILIFK 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 156 YLYN---GQISPIVKGLaaIGVNVDFFNKNIVLGSMANI-TTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIAT 231
Cdd:PRK10999  344 GLFNqsfGEINMMLSAL--FGIKPAWFSDPTLAKTMILIvNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFF 421


                  ....*
gi 1307934063 232 KIKLP 236
Cdd:PRK10999  422 KITLP 426
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
27-320 1.28e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 71.35  E-value: 1.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  27 KRENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFFrqvtegggaygggelvnkfVGFQNFQYVITSGNFWsgvgRVLVYT 106
Cdd:COG1178     3 TRPRRRPRLLLLLLALLLALLVLLPLLALLLRAFT-------------------DGLANFWALLSDPYLW----RALGNT 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 107 LIQV----PIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQisPIVKGLAAIGVNVDFFNkn 182
Cdd:COG1178    60 LLLAllvtLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPN--GLLNTLLRALFGLEPPD-- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 183 ivLGSMANIT---TWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNE 259
Cdd:COG1178   136 --IYGLGGIIlvlVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGT 213

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1307934063 260 PQIMStadpGISKSYTPMMMAMSTSQGSItpsgdGPASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:COG1178   214 PLVLG----GGYTTLTTAIYQAWLGDFDL-----GAAAALALVLLLLVLLLLLLERRLRRR 265
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
76-322 2.91e-13

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 68.70  E-value: 2.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  76 LVNKFVGFQNFQYVITSGNFWSGVGRVLVYTLIQVPIMIIAALALAIVIDsFVVKHVTGFRLGYFLPYAIPGVVASIIWV 155
Cdd:PRK10561   34 FSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVD-YVVRGSRFYQTLMLLPYAVAPAVAAVLWI 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 156 YLYNGQISPIVKGLAAIGVNVDFFNKN------IVLGSManittWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQI 229
Cdd:PRK10561  113 FLFNPGRGLITHFLAEFGYDWNHAQNSgqamflVVFASV-----WKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRR 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 230 ATKIKLPNVRGAALLAMLLSIVgtIQLFNEPQIMSTADPGISKSYTPMMMAMSTSQGSITPSGDGPASAIAIVMALIAGV 309
Cdd:PRK10561  188 FFKLALPLIAPVSFFLLVVNLV--YAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVL 265

                         250
                  ....*....|...
gi 1307934063 310 LAVLYTLAERKVN 322
Cdd:PRK10561  266 TVVQFRYVESKVR 278
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 30-320 1.82e-11

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 63.21  E-value: 1.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  30 NRTGWAFMAPFAVLFAFVFILPIIWAIYSSFFRQVTegggaygggeLVNKFVGF--QNFQYVITSGNFWSGVGRVLVYTL 107
Cdd:COG1177     2 SRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWF----------LTFPPEGFtlRWYAELFSDPRLLDALLNSLLIAL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 108 IQVPIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYngqispivkglAAIGVNVDFFNknIVLGS 187
Cdd:COG1177    72 LSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLF-----------SALGLSGGLWG--LILAH 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 188 maniTTWTFTgYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVR----GAALLAMLLSivgtiqlFNEPQIM 263
Cdd:COG1177   139 ----VVFTLP-FVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIApgilAGALLAFTLS-------FDEFVIT 206

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1307934063 264 S-TADPGISksyT-PMMMAMSTSQGsITPSgdgpASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:COG1177   207 LfLAGPGVT---TlPVYIYSMIRRG-ISPE----INALSTLLILLSLLLLLLAERLRRR 257
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 21-319 2.00e-11

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 63.58  E-value: 2.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  21 KRSGAQKRENRTGWAFMApFAVLFAFVFILPIIWAIYSSFFrqvTEGGGAYGGGELVNKFVGFQNFQYVITSGNFWSGVG 100
Cdd:COG0395     2 SATARRRRRRLGRILLYL-LLILLALLFLFPLYWMVVTSFK---PPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 101 RVLVYTLIQVPIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYN-----GQISPIVkgLAAIGVN 175
Cdd:COG0395    78 NSLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRqlgllNTYWGLI--LPYLAFG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 176 VDFfnknivlgsmaniTTWTFTGYnmliflaaLQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTiq 255
Cdd:COG0395   156 LPF-------------GIFLLRQF--------FRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGA-- 212

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1307934063 256 lFNE---PQIMSTadpgiSKSYTPMMMAMSTSQGSITPSgDGPASAIAIVMALiagVLAVLYTLAER 319
Cdd:COG0395   213 -WNDflwPLILLT-----SPDLRTLPVGLASFQGQYGTD-WGLLMAAAVIATL---PVLILFLFLQR 269
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 191-321 1.70e-09

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.15  E-value: 1.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 191 ITTWTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNEPQIMsTADPGI 270
Cdd:pfam00528  58 LALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL-GSWPGL 136

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1307934063 271 SksytpmMMAMSTSQGSITPSGDGPASAIAIVMALIAGVLAVLYTLAERKV 321
Cdd:pfam00528 137 G------LLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 34-262 1.72e-09

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 58.54  E-value: 1.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  34 WAFMAPFAVLFAFVFILPIIWAIYSSFFRQVTEgggaygggelvnkFVGFQNFQYVITSGNFWSGVGRVLVYTLIQVPIM 113
Cdd:TIGR03262   4 RLLLAGMILALLLFLLLPLLALLTKSVYDSDGD-------------FIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIV 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 114 IIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYNGQisPIVKGLAAIGVNVDFFNknIVLGSmaniTT 193
Cdd:TIGR03262  71 VPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQ--GLLKGLLGGFSIYGFWG--IVIGE----VF 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1307934063 194 WTFTgYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNEPQI 262
Cdd:TIGR03262 143 YTFP-HALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKV 210
permease_CysW TIGR02140
sulfate ABC transporter, permease protein CysW; This model represents CysW, one of two ...
 41-320 2.46e-08

sulfate ABC transporter, permease protein CysW; This model represents CysW, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysT (TIGR02139). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions]


Pssm-ID: 162725  Cd Length: 261  Bit Score: 53.93  E-value: 2.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  41 AVLFAFVFILPIIWAIYSSFFRQvtegggaygggelvnkfvGFQNFQYVITSGNFWSGVGRVLVYTLIQVPIMIIAALAL 120
Cdd:TIGR02140   9 ALGLLFLLLLLPLALIFQEAFEK------------------GFGVFFAAISDPDALSAIKLTLLVALIVVPLNTVFGVCA 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 121 AIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLY--NGQISPIvkgLAAIGVNVDFFNKNIVLGSManITTWTFTG 198
Cdd:TIGR02140  71 AWVLTRFQFPGKRLLLTIIDLPFSVSPVVAGLIFVLLYgsQGWLGPW---LEDLDIKIIFSLPGIVLATM--FVTCPFVA 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 199 YNMLiflAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLFNEPQIMSTADPGISKSYtPMM 278
Cdd:TIGR02140 146 RELI---PVMEEQGTEQEEAALTLGASWWQTFWRVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGKTNTL-PLH 221

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1307934063 279 MAMSTSQGSITpsgdgPASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:TIGR02140 222 VELLYNEYQSY-----AAFAAASLLALLALVTLVLKAILERR 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 103-257 8.39e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 51.51  E-value: 8.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 103 LVYTLIQVPIMIIAALALAIVIDSFVVKHVTGFRLGYFLPYAIPGVVASIIWVYLYngqispivKGLAAIGVNVDFFNKN 182
Cdd:cd06261     5 LLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF--------GVLLGWGILPGLGLPA 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1307934063 183 IVLGSManittwTFTGYNMLIFLAALQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLLSIVGTIQLF 257
Cdd:cd06261    77 LILALL------LIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 21-254 1.91e-06

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 48.61  E-value: 1.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063  21 KRSGAQKRENRTGWAFMAPFAVLFAFVFILPIIWAIYSSFfrqvtEGGGAYGGGELVNKFVGFQNFQYVITSGNFWSGVG 100
Cdd:COG3833     2 SRRKSRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASF-----NPGGSLYSSSLIPENFTLENYKKLFTETPFLRWFL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 101 RVLVY----TLIQVPIMIIAALALAividSFVVKHVTGFRLGYFLPYAIPGVvASIIWVY-------LYNGQISPIVKGL 169
Cdd:COG3833    77 NSLIVavvtAIISVFLAALAAYAFS----RFRFKGRKAGLLALLLLQMFPAF-LALVALYlllsalgLLNTLLGLILVYL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 170 A-AIGVNvdffnknivlgsmanitTWTFTGYnmliflaaLQAIPHDLYEAARIDGANGWQIATKIKLPNVRGAALLAMLL 248
Cdd:COG3833   152 GgAIPFN-----------------TWLMKGY--------FDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALL 206


                  ....*.
gi 1307934063 249 SIVGTI 254
Cdd:COG3833   207 SFIGPW 212
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 141-320 7.87e-05

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 43.59  E-value: 7.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 141 LPYAIPGVVASIIWVYLY--NGQISPIvkgLAAIGVNVDFFNKNIVLGSmanittwTFTG--YNMLIFLAALQAIPHDLY 216
Cdd:COG0555    98 LPFALPTAVAGIALLLLFgpNGWLGQL---LAPLGIKVAFTPLGIVLAQ-------TFVSlpFVVRTVQPVLEELDPELE 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1307934063 217 EAARIDGANGWQIATKIKLPNVRGAALLAMLLS-------------IVGTIQLFNEPqimstadpgisksyTPMMMAMST 283
Cdd:COG0555   168 EAAATLGASRWQTFRRVILPLLLPALLTGFALAfaralgefgavifIAGNLPMKTEI--------------LPLLIYLKL 233

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1307934063 284 SQGSITpsgdgPASAIAIVMALIAGVLAVLYTLAERK 320
Cdd:COG0555   234 EEGDYA-----GATAIALVLLLISFLLLLLINLLQRR 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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