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Conserved domains on  [gi|1213400461|gb|ASG06908|]
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hypothetical protein CEQ50_04865 [Vibrio anguillarum]

Protein Classification

YbeD family protein( domain architecture ID 10012243)

YbeD family protein is a DUF493 domain-containing protein similar to Escherichia coli UPF0250 protein YbeD, which may play a role in the allosteric regulation of lipoic acid biosynthesis or the glycine cleavage system

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK04998 PRK04998
hypothetical protein; Provisional
7-92 6.62e-59

hypothetical protein; Provisional


:

Pssm-ID: 179912  Cd Length: 88  Bit Score: 174.71  E-value: 6.62e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461  7 DAKLKDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPGDYSPRVKPSAKGTYHSLSINITATSIEQVEILYKELGEID 86
Cdd:PRK04998   3 KTKLKELLEFPCSFTYKVMGLARPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITITATSIEQVETLYEELAKIE 82

                 ....*.
gi 1213400461 87 IVRMVL 92
Cdd:PRK04998  83 GVRMVL 88
 
Name Accession Description Interval E-value
PRK04998 PRK04998
hypothetical protein; Provisional
7-92 6.62e-59

hypothetical protein; Provisional


Pssm-ID: 179912  Cd Length: 88  Bit Score: 174.71  E-value: 6.62e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461  7 DAKLKDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPGDYSPRVKPSAKGTYHSLSINITATSIEQVEILYKELGEID 86
Cdd:PRK04998   3 KTKLKELLEFPCSFTYKVMGLARPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITITATSIEQVETLYEELAKIE 82

                 ....*.
gi 1213400461 87 IVRMVL 92
Cdd:PRK04998  83 GVRMVL 88
YbeD COG2921
Putative lipoate-binding regulatory protein, UPF0250 family [Signal transduction mechanisms];
7-92 2.50e-39

Putative lipoate-binding regulatory protein, UPF0250 family [Signal transduction mechanisms];


Pssm-ID: 442165  Cd Length: 88  Bit Score: 125.28  E-value: 2.50e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461  7 DAKLKDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPgDYSP---RVKPSAKGTYHSLSINITATSIEQVEILYKELG 83
Cdd:COG2921    1 STKEEPLIEFPCDFPIKVMGLADDDFVDAVVEVVQRHAP-DFDPetiSVRPSSKGKYLSVTVTITATSREQLDALYRALT 79

                 ....*....
gi 1213400461 84 EIDIVRMVL 92
Cdd:COG2921   80 AHPLVKMVL 88
DUF493 pfam04359
Protein of unknown function (DUF493); This domain is likely to act in a regulatory capacity ...
11-92 2.80e-34

Protein of unknown function (DUF493); This domain is likely to act in a regulatory capacity like pfam01842 domains. This domain has a remarkable property in that the C-terminal residue of every protein in the family lies up in the alignment. This suggests that the C-terminal residue plays some important functional role (Bateman A pers obs).


Pssm-ID: 461274  Cd Length: 84  Bit Score: 112.60  E-value: 2.80e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461 11 KDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPgDYSP---RVKPSAKGTYHSLSINITATSIEQVEILYKELGEIDI 87
Cdd:pfam04359  1 EPLIEFPCDFPIKVIGLAEDDFVDAVVEVVQRHAP-DFDPetvEVRPSSKGKYVSVTVTVTVTSREQLDAIYRALKAHPR 79

                 ....*
gi 1213400461 88 VRMVL 92
Cdd:pfam04359 80 VKMVL 84
 
Name Accession Description Interval E-value
PRK04998 PRK04998
hypothetical protein; Provisional
7-92 6.62e-59

hypothetical protein; Provisional


Pssm-ID: 179912  Cd Length: 88  Bit Score: 174.71  E-value: 6.62e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461  7 DAKLKDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPGDYSPRVKPSAKGTYHSLSINITATSIEQVEILYKELGEID 86
Cdd:PRK04998   3 KTKLKELLEFPCSFTYKVMGLARPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITITATSIEQVETLYEELAKIE 82

                 ....*.
gi 1213400461 87 IVRMVL 92
Cdd:PRK04998  83 GVRMVL 88
YbeD COG2921
Putative lipoate-binding regulatory protein, UPF0250 family [Signal transduction mechanisms];
7-92 2.50e-39

Putative lipoate-binding regulatory protein, UPF0250 family [Signal transduction mechanisms];


Pssm-ID: 442165  Cd Length: 88  Bit Score: 125.28  E-value: 2.50e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461  7 DAKLKDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPgDYSP---RVKPSAKGTYHSLSINITATSIEQVEILYKELG 83
Cdd:COG2921    1 STKEEPLIEFPCDFPIKVMGLADDDFVDAVVEVVQRHAP-DFDPetiSVRPSSKGKYLSVTVTITATSREQLDALYRALT 79

                 ....*....
gi 1213400461 84 EIDIVRMVL 92
Cdd:COG2921   80 AHPLVKMVL 88
DUF493 pfam04359
Protein of unknown function (DUF493); This domain is likely to act in a regulatory capacity ...
11-92 2.80e-34

Protein of unknown function (DUF493); This domain is likely to act in a regulatory capacity like pfam01842 domains. This domain has a remarkable property in that the C-terminal residue of every protein in the family lies up in the alignment. This suggests that the C-terminal residue plays some important functional role (Bateman A pers obs).


Pssm-ID: 461274  Cd Length: 84  Bit Score: 112.60  E-value: 2.80e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461 11 KDLLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPgDYSP---RVKPSAKGTYHSLSINITATSIEQVEILYKELGEIDI 87
Cdd:pfam04359  1 EPLIEFPCDFPIKVIGLAEDDFVDAVVEVVQRHAP-DFDPetvEVRPSSKGKYVSVTVTVTVTSREQLDAIYRALKAHPR 79

                 ....*
gi 1213400461 88 VRMVL 92
Cdd:pfam04359 80 VKMVL 84
PRK02047 PRK02047
hypothetical protein; Provisional
13-92 7.16e-16

hypothetical protein; Provisional


Pssm-ID: 179360  Cd Length: 91  Bit Score: 65.97  E-value: 7.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461 13 LLEFPCSFTYKVMGHAKPELPEKVLEVIQRHAPGDYSPRV--KPSAKGTYHSLSINITATSIEQVEILYKELGEIDIVRM 90
Cdd:PRK02047  10 LIEYPSDFPIKVMGKAHPEFADTIFKVVSVHDPEFDLEKIeeRPSSGGNYTGLTITVRATSREQLDNIYRALTGHPMVKV 89

                 ..
gi 1213400461 91 VL 92
Cdd:PRK02047  90 VL 91
PRK00341 PRK00341
DUF493 domain-containing protein;
14-92 1.43e-11

DUF493 domain-containing protein;


Pssm-ID: 166914  Cd Length: 91  Bit Score: 55.18  E-value: 1.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1213400461 14 LEFPC-SFTYKVMGHAKPELPEKVLEVIQRHAPGDYSP-RVKPSAKGTYHSLSINITATSIEQVEILYKELGEIDIVRMV 91
Cdd:PRK00341  11 IEFPCeDYPIKVIGDTGVGFKDLVIEILQKHADVDLSTlAERQSSNGKYTTVQLHIVATDEDQLQDINSALRATGRVHMV 90

                 .
gi 1213400461 92 L 92
Cdd:PRK00341  91 L 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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