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Conserved domains on  [gi|1143275849|gb|AQM42186|]
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ABC transporter substrate-binding protein [Bifidobacterium breve]

Protein Classification

ABC transporter substrate-binding protein( domain architecture ID 11447308)

ABC transporter substrate-binding protein functions as the initial receptor in the ABC transport of one or more from a variety of substrates including carbohydrates

Gene Ontology:  GO:0140359|GO:0042626|GO:0055052
PubMed:  26517916|24638992|25750732|26517916
SCOP:  3000083
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpB COG1653
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport ...
 16-361 6.47e-36

ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport and metabolism];


:

Pssm-ID: 441259 [Multi-domain]  Cd Length: 363  Bit Score: 135.94  E-value: 6.47e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  16 LVSVAALSFGALAACG---NTTAVDSSKGRVYYLNKKAEEQEKWEALAQAFQDET-GIE-TQIQLSATDYDQTLRSEMAK 90
Cdd:COG1653     5 ALALAAALALALAACGgggSGAAAAAGKVTLTVWHTGGGEAAALEALIKEFEAEHpGIKvEVESVPYDDYRTKLLTALAA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  91 DEAPTMFQADGPSFM-YSWLDYAADMSDS-KIYGELTDSYKDRTLKNA--DGKPVGIPYAVESYGIIYNKSLLKKYfdas 166
Cdd:COG1653    85 GNAPDVVQVDSGWLAeFAAAGALVPLDDLlDDDGLDKDDFLPGALDAGtyDGKLYGVPFNTDTLGLYYNKDLFEKA---- 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 167 wssvkSIDGLNNFKALKTVADEIQEHKDDMGvkgaFTSAGMDSSAFrynfhlpsLPLFYE-----YRDDG-VDMNSvPES 240
Cdd:COG1653   161 -----GLDPPKTWDELLAAAKKLKAKDGVYG----FALGGKDGAAW--------LDLLLSaggdlYDEDGkPAFDS-PEA 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 241 VKGtyVDYMQNIYDlyitDATVPASSLsGKTMDDATSEFALGEAVFFQDGVWIYSALQDQGfPDEDLGVLPIYMGVDGEE 320
Cdd:COG1653   223 VEA--LEFLKDLVK----DGYVPPGAL-GTDWDDARAAFASGKAAMMINGSWALGALKDAA-PDFDVGVAPLPGGPGGKK 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1143275849 321 KQGLnqVISNYWCVNSKSsqKDQEATQQFLEWLVTSDAARE 361
Cdd:COG1653   295 PASV--LGGSGLAIPKGS--KNPEAAWKFLKFLTSPEAQAK 331
 
Name Accession Description Interval E-value
UgpB COG1653
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport ...
 16-361 6.47e-36

ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport and metabolism];


Pssm-ID: 441259 [Multi-domain]  Cd Length: 363  Bit Score: 135.94  E-value: 6.47e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  16 LVSVAALSFGALAACG---NTTAVDSSKGRVYYLNKKAEEQEKWEALAQAFQDET-GIE-TQIQLSATDYDQTLRSEMAK 90
Cdd:COG1653     5 ALALAAALALALAACGgggSGAAAAAGKVTLTVWHTGGGEAAALEALIKEFEAEHpGIKvEVESVPYDDYRTKLLTALAA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  91 DEAPTMFQADGPSFM-YSWLDYAADMSDS-KIYGELTDSYKDRTLKNA--DGKPVGIPYAVESYGIIYNKSLLKKYfdas 166
Cdd:COG1653    85 GNAPDVVQVDSGWLAeFAAAGALVPLDDLlDDDGLDKDDFLPGALDAGtyDGKLYGVPFNTDTLGLYYNKDLFEKA---- 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 167 wssvkSIDGLNNFKALKTVADEIQEHKDDMGvkgaFTSAGMDSSAFrynfhlpsLPLFYE-----YRDDG-VDMNSvPES 240
Cdd:COG1653   161 -----GLDPPKTWDELLAAAKKLKAKDGVYG----FALGGKDGAAW--------LDLLLSaggdlYDEDGkPAFDS-PEA 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 241 VKGtyVDYMQNIYDlyitDATVPASSLsGKTMDDATSEFALGEAVFFQDGVWIYSALQDQGfPDEDLGVLPIYMGVDGEE 320
Cdd:COG1653   223 VEA--LEFLKDLVK----DGYVPPGAL-GTDWDDARAAFASGKAAMMINGSWALGALKDAA-PDFDVGVAPLPGGPGGKK 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1143275849 321 KQGLnqVISNYWCVNSKSsqKDQEATQQFLEWLVTSDAARE 361
Cdd:COG1653   295 PASV--LGGSGLAIPKGS--KNPEAAWKFLKFLTSPEAQAK 331
SBP_bac_8 pfam13416
Bacterial extracellular solute-binding protein; This family includes bacterial extracellular ...
 58-388 6.39e-26

Bacterial extracellular solute-binding protein; This family includes bacterial extracellular solute-binding proteins.


Pssm-ID: 433189 [Multi-domain]  Cd Length: 281  Bit Score: 106.34  E-value: 6.39e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  58 ALAQAFQDETGIETQIQLSAT-DYDQTLRSEMAKDEAPT--MFQADGPSFM-YSWLDYAADMSDSKIYGELTDSYKDRTL 133
Cdd:pfam13416   1 ALAKAFEKKTGVTVEVEPQASnDLQAKLLAAAAAGNAPDldVVWIAADQLAtLAEAGLLADLSDVDNLDDLPDALDAAGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 134 knaDGKPVGIPYAVES-YGIIYNKSLLKKyfdaSWSSVKSIDGLNNFKAlktvadeiqehkddmGVKGAFTSAgMDSSAF 212
Cdd:pfam13416  81 ---DGKLYGVPYAASTpTVLYYNKDLLKK----AGEDPKTWDELLAAAA---------------KLKGKTGLT-DPATGW 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 213 RYNFhlpslpLFYEYRDDGVDMNSVPESVKgtYVDYMQNIYDlyitDATVPASSlsgktmDDATSEFALGEAVFFQDGVW 292
Cdd:pfam13416 138 LLWA------LLADGVDLTDDGKGVEALDE--ALAYLKKLKD----NGKVYNTG------ADAVQLFANGEVAMTVNGTW 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 293 IYSALQDQGFPdedLGVLPIYMG--VDGEekqglnqvisnYWCVNSKSSqKDQEATQQFLEWLvTSDAARESISQDMGLV 370
Cdd:pfam13416 200 AAAAAKKAGKK---LGAVVPKDGsfLGGK-----------GLVVPAGAK-DPRLAALDFIKFL-TSPENQAALAEDTGYI 263

                         330
                  ....*....|....*...
gi 1143275849 371 TPFKTFDEEAYTVKNPLV 388
Cdd:pfam13416 264 PANKSAALSDEVKADPAL 281
PBP2_TMBP_like cd13585
The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and ...
 50-361 1.40e-17

The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold; This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270303 [Multi-domain]  Cd Length: 383  Bit Score: 83.99  E-value: 1.40e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  50 AEEQEKWEALAQAFQDE-TGIETQ-IQLSATDYDQTLRSEMAKDEAPTMFQADGPSF-MYSWLDYAADMSDSKIYGELTD 126
Cdd:cd13585    10 PAETAALKKLIDAFEKEnPGVKVEvVPVPYDDYWTKLTTAAAAGTAPDVFYVDGPWVpEFASNGALLDLDDYIEKDGLDD 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 127 SYKDRTLK--NADGKPVGIPYAVESYGIIYNKSLLKKYFDASwssvksidglnnfKALKTVADEI---QEHKDDMGVKGA 201
Cdd:cd13585    90 DFPPGLLDagTYDGKLYGLPFDADTLVLFYNKDLFDKAGPGP-------------KPPWTWDELLeaaKKLTDKKGGQYG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 202 FTSAGMDSSAFRYnfhlpsLPLFYEY------RDDG-VDMNSvPESVKGtyvdyMQNIYDLYiTDATVPASSLSGKtmDD 274
Cdd:cd13585   157 FALRGGSGGQTQW------YPFLWSNggdlldEDDGkATLNS-PEAVEA-----LQFYVDLY-KDGVAPSSATTGG--DE 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 275 ATSEFALGEAVFFQDGVWIYSALQDQGfPDEDLGVLPIYMGVDGEEKQGLNqviSNYWCVNSKSsqKDQEATQQFLEWLV 354
Cdd:cd13585   222 AVDLFASGKVAMMIDGPWALGTLKDSK-VKFKWGVAPLPAGPGGKRASVLG---GWGLAISKNS--KHPEAAWKFIKFLT 295


                  ....*..
gi 1143275849 355 TSDAARE 361
Cdd:cd13585   296 SKENQLK 302
malE PRK09474
maltose/maltodextrin ABC transporter substrate-binding protein MalE;
13-398 4.01e-06

maltose/maltodextrin ABC transporter substrate-binding protein MalE;


Pssm-ID: 236533 [Multi-domain]  Cd Length: 396  Bit Score: 48.85  E-value: 4.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  13 AIGLVSVAALSFGALAAC--GNTTA-VDSSKGrvyYlNKKAEEQEKWEAlaqafqdETGIETQIQL--SATD-YDQTlrs 86
Cdd:PRK09474   11 ALSALATLMFSASALAKIeeGKLVIwINGDKG---Y-NGLAEVGKKFEK-------DTGIKVTVEHpdKLEEkFPQV--- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  87 emakdeAPTmfqADGPSFMYSWLDYAADMSDSKIYGELTDS--YKDRTLKNA------DGKPVGIPYAVESYGIIYNKSL 158
Cdd:PRK09474   77 ------AAT---GDGPDIIFWAHDRFGGYAQSGLLAEVTPSkaFKDKLVPFTwdavryNGKLIGYPIAVEALSLIYNKDL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 159 LKKYfDASWSSVKSIDglnnfKALKTvadeiqehkddmgvKGaftsagmdSSAFRYNFHLP--SLPLF-------YEYRD 229
Cdd:PRK09474  148 VPTP-PKTWEEIPALD-----KELKA--------------KG--------KSAIMWNLQEPyfTWPLIaadggyaFKFEN 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 230 DGVDMNSVPESVKGTyVDYMQNIYDLyITDATVPAsslsgkTMDDATSE--FALGEAVFFQDGVWIYSALQDQGFpdeDL 307
Cdd:PRK09474  200 GGYDVKDVGVNNAGA-KAGLQFLVDL-VKNKHMNA------DTDYSIAEaaFNKGETAMTINGPWAWSNIDKSGI---NY 268

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 308 GVLPIyMGVDGEEKQGLNQVISNywCVNSKSSQKDqeATQQFLEWLVTSDAARESISQDMGL-VTPFKTFDEEayTVKNP 386
Cdd:PRK09474  269 GVTVL-PTFNGKPSKPFVGVLSA--GINAASPNKE--LAKEFLENYLLTDEGLETVNKDKPLgAVALKSFQEE--LAKDP 341

                         410
                  ....*....|..
gi 1143275849 387 LVEANREYQENG 398
Cdd:PRK09474  342 RIAATMDNAQNG 353
 
Name Accession Description Interval E-value
UgpB COG1653
ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport ...
 16-361 6.47e-36

ABC-type glycerol-3-phosphate transport system, periplasmic component [Carbohydrate transport and metabolism];


Pssm-ID: 441259 [Multi-domain]  Cd Length: 363  Bit Score: 135.94  E-value: 6.47e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  16 LVSVAALSFGALAACG---NTTAVDSSKGRVYYLNKKAEEQEKWEALAQAFQDET-GIE-TQIQLSATDYDQTLRSEMAK 90
Cdd:COG1653     5 ALALAAALALALAACGgggSGAAAAAGKVTLTVWHTGGGEAAALEALIKEFEAEHpGIKvEVESVPYDDYRTKLLTALAA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  91 DEAPTMFQADGPSFM-YSWLDYAADMSDS-KIYGELTDSYKDRTLKNA--DGKPVGIPYAVESYGIIYNKSLLKKYfdas 166
Cdd:COG1653    85 GNAPDVVQVDSGWLAeFAAAGALVPLDDLlDDDGLDKDDFLPGALDAGtyDGKLYGVPFNTDTLGLYYNKDLFEKA---- 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 167 wssvkSIDGLNNFKALKTVADEIQEHKDDMGvkgaFTSAGMDSSAFrynfhlpsLPLFYE-----YRDDG-VDMNSvPES 240
Cdd:COG1653   161 -----GLDPPKTWDELLAAAKKLKAKDGVYG----FALGGKDGAAW--------LDLLLSaggdlYDEDGkPAFDS-PEA 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 241 VKGtyVDYMQNIYDlyitDATVPASSLsGKTMDDATSEFALGEAVFFQDGVWIYSALQDQGfPDEDLGVLPIYMGVDGEE 320
Cdd:COG1653   223 VEA--LEFLKDLVK----DGYVPPGAL-GTDWDDARAAFASGKAAMMINGSWALGALKDAA-PDFDVGVAPLPGGPGGKK 294

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1143275849 321 KQGLnqVISNYWCVNSKSsqKDQEATQQFLEWLVTSDAARE 361
Cdd:COG1653   295 PASV--LGGSGLAIPKGS--KNPEAAWKFLKFLTSPEAQAK 331
MalE COG2182
Maltose-binding periplasmic protein MalE [Carbohydrate transport and metabolism];
12-443 4.44e-27

Maltose-binding periplasmic protein MalE [Carbohydrate transport and metabolism];


Pssm-ID: 441785 [Multi-domain]  Cd Length: 410  Bit Score: 112.35  E-value: 4.44e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  12 KAIGLVSVAALSFGALAACGNTTAVDSSKG--------RVYYlnkKAEEQEKWEALAQAFQDETGIETQIQ-LSATDYDQ 82
Cdd:COG2182     4 RLLAALALALALALALAACGSGSSSSGSSSaagaggtlTVWV---DDDEAEALEEAAAAFEEEPGIKVKVVeVPWDDLRE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  83 TLRSEMAKDEAPTMFQADGPsFMYSWLD--YAADMSDSKiygELTDSYKDRTLKNA--DGKPVGIPYAVESYGIIYNKSL 158
Cdd:COG2182    81 KLTTAAPAGKGPDVFVGAHD-WLGELAEagLLAPLDDDL---ADKDDFLPAALDAVtyDGKLYGVPYAVETLALYYNKDL 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 159 LKKyfdaswSSVKSIDGLnnFKALKTVADEiqehkddmGVKGaFTSAGMDSsafrynFHLPSL------PLFYEYRDDG- 231
Cdd:COG2182   157 VKA------EPPKTWDEL--IAAAKKLTAA--------GKYG-LAYDAGDA------YYFYPFlaafggYLFGKDGDDPk 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 232 -VDMNSvPESVKGtyVDYMQNIYDlyitDATVPASSlsgkTMDDATSEFALGEAVFFQDGVWIYSALQDQGfpDEDLGVL 310
Cdd:COG2182   214 dVGLNS-PGAVAA--LEYLKDLIK----DGVLPADA----DYDAADALFAEGKAAMIINGPWAAADLKKAL--GIDYGVA 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 311 PIYMGVDGEEKQGLNQVISnyWCVNSKSsqKDQEATQQFLEWLVTSDAAREsISQDMGLVTPFKTFDEEAYTVKNPLVEA 390
Cdd:COG2182   281 PLPTLAGGKPAKPFVGVKG--FGVSAYS--KNKEAAQEFAEYLTSPEAQKA-LFEATGRIPANKAAAEDAEVKADPLIAA 355

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143275849 391 NREYQENGYYdVISVSTVSHQWEkDLGSAELNYAQGQGD----WDAVKKVFTDDWAK 443
Cdd:COG2182   356 FAEQAEYAVP-MPNIPEMGAVWT-PLGTALQAIASGKADpaeaLDAAQKQIEAAIAQ 410
SBP_bac_8 pfam13416
Bacterial extracellular solute-binding protein; This family includes bacterial extracellular ...
 58-388 6.39e-26

Bacterial extracellular solute-binding protein; This family includes bacterial extracellular solute-binding proteins.


Pssm-ID: 433189 [Multi-domain]  Cd Length: 281  Bit Score: 106.34  E-value: 6.39e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  58 ALAQAFQDETGIETQIQLSAT-DYDQTLRSEMAKDEAPT--MFQADGPSFM-YSWLDYAADMSDSKIYGELTDSYKDRTL 133
Cdd:pfam13416   1 ALAKAFEKKTGVTVEVEPQASnDLQAKLLAAAAAGNAPDldVVWIAADQLAtLAEAGLLADLSDVDNLDDLPDALDAAGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 134 knaDGKPVGIPYAVES-YGIIYNKSLLKKyfdaSWSSVKSIDGLNNFKAlktvadeiqehkddmGVKGAFTSAgMDSSAF 212
Cdd:pfam13416  81 ---DGKLYGVPYAASTpTVLYYNKDLLKK----AGEDPKTWDELLAAAA---------------KLKGKTGLT-DPATGW 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 213 RYNFhlpslpLFYEYRDDGVDMNSVPESVKgtYVDYMQNIYDlyitDATVPASSlsgktmDDATSEFALGEAVFFQDGVW 292
Cdd:pfam13416 138 LLWA------LLADGVDLTDDGKGVEALDE--ALAYLKKLKD----NGKVYNTG------ADAVQLFANGEVAMTVNGTW 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 293 IYSALQDQGFPdedLGVLPIYMG--VDGEekqglnqvisnYWCVNSKSSqKDQEATQQFLEWLvTSDAARESISQDMGLV 370
Cdd:pfam13416 200 AAAAAKKAGKK---LGAVVPKDGsfLGGK-----------GLVVPAGAK-DPRLAALDFIKFL-TSPENQAALAEDTGYI 263

                         330
                  ....*....|....*...
gi 1143275849 371 TPFKTFDEEAYTVKNPLV 388
Cdd:pfam13416 264 PANKSAALSDEVKADPAL 281
PBP2_TMBP_like cd13585
The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and ...
 50-361 1.40e-17

The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold; This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270303 [Multi-domain]  Cd Length: 383  Bit Score: 83.99  E-value: 1.40e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  50 AEEQEKWEALAQAFQDE-TGIETQ-IQLSATDYDQTLRSEMAKDEAPTMFQADGPSF-MYSWLDYAADMSDSKIYGELTD 126
Cdd:cd13585    10 PAETAALKKLIDAFEKEnPGVKVEvVPVPYDDYWTKLTTAAAAGTAPDVFYVDGPWVpEFASNGALLDLDDYIEKDGLDD 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 127 SYKDRTLK--NADGKPVGIPYAVESYGIIYNKSLLKKYFDASwssvksidglnnfKALKTVADEI---QEHKDDMGVKGA 201
Cdd:cd13585    90 DFPPGLLDagTYDGKLYGLPFDADTLVLFYNKDLFDKAGPGP-------------KPPWTWDELLeaaKKLTDKKGGQYG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 202 FTSAGMDSSAFRYnfhlpsLPLFYEY------RDDG-VDMNSvPESVKGtyvdyMQNIYDLYiTDATVPASSLSGKtmDD 274
Cdd:cd13585   157 FALRGGSGGQTQW------YPFLWSNggdlldEDDGkATLNS-PEAVEA-----LQFYVDLY-KDGVAPSSATTGG--DE 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 275 ATSEFALGEAVFFQDGVWIYSALQDQGfPDEDLGVLPIYMGVDGEEKQGLNqviSNYWCVNSKSsqKDQEATQQFLEWLV 354
Cdd:cd13585   222 AVDLFASGKVAMMIDGPWALGTLKDSK-VKFKWGVAPLPAGPGGKRASVLG---GWGLAISKNS--KHPEAAWKFIKFLT 295


                  ....*..
gi 1143275849 355 TSDAARE 361
Cdd:cd13585   296 SKENQLK 302
PBP2_XBP1_like cd14749
The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; ...
 43-362 3.29e-13

The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold; This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270452 [Multi-domain]  Cd Length: 388  Bit Score: 70.87  E-value: 3.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  43 VYYLNKKAEEQEKWEALAQAFQDET-GIETQIQLSATDYDQT-LRSEMAKDEAPTMFQADGPSFMYSWLD--YAADMSDS 118
Cdd:cd14749     4 YWQYFTGDTKKKYMDELIADFEKENpNIKVKVVVFPYDNYKTkLKTAVAAGEGPDVFNLWPGGWLAEFVKagLLLPLTDY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 119 KIYGELTDSYKDRTLKNA--DGKPVGIPYAVESYGIIYNKSLLKKYfdaswssvksidglNNFKALKT---VADEIQEHK 193
Cdd:cd14749    84 LDPNGVDKRFLPGLADAVtfNGKVYGIPFAARALALFYNKDLFEEA--------------GGVKPPKTwdeLIEAAKKDK 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 194 DDMGVKGAFTSAGMDSSAFrynfhlpslpLFYEY--RDDGVDMNSVPESVKGTY-----VDYMQNIYDLYITDATVPAss 266
Cdd:cd14749   150 FKAKGQTGFGLLLGAQGGH----------WYFQYlvRQAGGGPLSDDGSGKATFndpafVQALQKLQDLVKAGAFQEG-- 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 267 LSGKTMDDATSEFALGEAVFFQDGVWIYSALqDQGFPDEDLGVLPIYMGVDGEEKQglnQVISNYWCVNSKSSQKDQEAT 346
Cdd:cd14749   218 FEGIDYDDAGQAFAQGKAAMNIGGSWDLGAI-KAGEPGGKIGVFPFPTVGKGAQTS---TIGGSDWAIAISANGKKKEAA 293

                         330
                  ....*....|....*.
gi 1143275849 347 QQFLEWLVTSDAARES 362
Cdd:cd14749   294 VKFLKYLTSPEVMKQY 309
PBP2_CMBP cd13658
The periplasmic binding component of ABC transport systems specific for cyclo/maltodextrin; ...
 125-390 3.45e-13

The periplasmic binding component of ABC transport systems specific for cyclo/maltodextrin; possess the type 2 periplasmic binding fold; This group includes the periplasmic cyclo/maltodextrin-binding protein of Thermoactinomyces vulgaris ATP-binding cassette transporter and related proteins. Cyclodextrins are a family of compounds composed of glucose units connected by 1, 4 glycosidic linkages to form a series of oligosaccharide rings, and their cavity is hydrophibic which allows cyclodextrins to accomodate hydrophobic molecules/moieties in the cavity. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270376 [Multi-domain]  Cd Length: 372  Bit Score: 70.59  E-value: 3.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 125 TDSYKDRTLK--NADGKPVGIPYAVESYGIIYNKSLLKkyfdaswssvksidglnnfKALKTVADEIQEHKDDMGVKGAF 202
Cdd:cd13658    83 KKGFTDQALKalTYDGKLYGLPAAVETLALYYNKDLVK-------------------NAPKTFDELEALAKDLTKEKGKQ 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 203 TSAGMDSSAFRYNFhlpslPLFYEY-------RDDGVDMNSV----PESVKGtyVDYMQNIYdlyiTDATVPAsSLSGKT 271
Cdd:cd13658   144 YGFLADATNFYYSY-----GLLAGNggyifkkNGSDLDINDIglnsPGAVKA--VKFLKKWY----TEGYLPK-GMTGDV 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 272 MDdatSEFALGEAVFFQDGVWIYSALQDQGFpdeDLGVLPIYMGVDGEEKQ----GLNQVISNYwcvnskssQKDQEATQ 347
Cdd:cd13658   212 IQ---GLFKEGKAAAVIDGPWAIQEYQEAGV---NYGVAPLPTLPNGKPMApflgVKGWYLSAY--------SKHKEWAQ 277

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1143275849 348 QFLEWLvTSDAARESISQDMGLVTPFKTFDEEAYTVKNPLVEA 390
Cdd:cd13658   278 KFMEFL-TSKENLKKRYDETNEIPPRKDVRSDPEIKNNPLTSA 319
SBP_bac_1 pfam01547
Bacterial extracellular solute-binding protein; This family also includes the bacterial ...
 51-359 4.37e-12

Bacterial extracellular solute-binding protein; This family also includes the bacterial extracellular solute-binding protein family POTD/POTF.


Pssm-ID: 460248 [Multi-domain]  Cd Length: 294  Bit Score: 66.67  E-value: 4.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  51 EEQEKWEALAQAFQ-DETGIETQIQ-LSATDYDQTLRSEMAKDEAPtmfqADgpsFMYSWLDYAADMSDSKIYGELtDSY 128
Cdd:pfam01547   5 TEAAALQALVKEFEkEHPGIKVEVEsVGSGSLAQKLTTAIAAGDGP----AD---VFASDNDWIAELAKAGLLLPL-DDY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 129 KDRTLKNADGKPVGIPYAVESYGIIYNKSLLKKYfdaswssvkSIDGLNNFKALKTVADEIQEHKDDMGVKGAFTSAGmD 208
Cdd:pfam01547  77 VANYLVLGVPKLYGVPLAAETLGLIYNKDLFKKA---------GLDPPKTWDELLEAAKKLKEKGKSPGGAGGGDASG-T 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 209 SSAFRYNFHLPSLPLFYEYRDDGVDmnsvpESVKGTYVDYMQNIYDLYITDATVPASSLSGKTMDDATSEFALGEAVFFQ 288
Cdd:pfam01547 147 LGYFTLALLASLGGPLFDKDGGGLD-----NPEAVDAITYYVDLYAKVLLLKKLKNPGVAGADGREALALFEQGKAAMGI 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1143275849 289 DGVWIYSALQDQG---FPDEDLGVLPIYMGVDGEEKQGLNQVISNYWCVNSKSsqKDQEATQQFLEWLVTSDAA 359
Cdd:pfam01547 222 VGPWAALAANKVKlkvAFAAPAPDPKGDVGYAPLPAGKGGKGGGYGLAIPKGS--KNKEAAKKFLDFLTSPEAQ 293
PBP2_Maltose_binding_like cd13586
The periplasmic-binding component of ABC transport systems specific for maltose and related ...
 51-390 9.72e-12

The periplasmic-binding component of ABC transport systems specific for maltose and related polysaccharides; possess type 2 periplasmic binding fold; This subfamily represents the periplasmic binding component of ABC transport systems involved in uptake of polysaccharides including maltose, maltodextrin, and cyclodextrin. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270304 [Multi-domain]  Cd Length: 367  Bit Score: 66.16  E-value: 9.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  51 EEQEKWEALAQAFQDETGIETQIQLSATDydqTLRSEMAKDeAPTmfqADGPSFMYSWLDYAADMSDSKIYGELtDSYKD 130
Cdd:cd13586    10 GELEYLKELAEEFEKKYGIKVEVVYVDSG---DTREKFITA-GPA---GKGPDVFFGPHDWLGELAAAGLLAPI-PEYLA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 131 RTLKNA---------DGKPVGIPYAVESYGIIYNKSLLKkyfdaswssvksidglnnfKALKTVADEIQEHKDDMGVKGa 201
Cdd:cd13586    82 VKIKNLpvalaavtyNGKLYGVPVSVETIALFYNKDLVP-------------------EPPKTWEELIALAKKFNDKAG- 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 202 ftsagmDSSAFRYNFHLP--SLPLF-----YEYRDDGVDMNSV----PESVKGtyvdyMQNIYDLyITDATVPASSLSGK 270
Cdd:cd13586   142 ------GKYGFAYDQTNPyfSYPFLaafggYVFGENGGDPTDIglnnEGAVKG-----LKFIKDL-KKKYKVLPPDLDYD 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 271 TMDdatSEFALGEAVFFQDGVWIYSALQDQGFpdeDLGVLPIYMgVDGeEKQGLNQVISNYWCVNSKSsqKDQEATQQFL 350
Cdd:cd13586   210 IAD---ALFKEGKAAMIINGPWDLADYKDAGI---NFGVAPLPT-LPG-GKQAAPFVGVQGAFVSAYS--KNKEAAVEFA 279

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1143275849 351 EWLvTSDAARESISQDMGLVTPFKTFDEEAYTVKNPLVEA 390
Cdd:cd13586   280 EYL-TSDEAQLLLFEKTGRIPALKDALNDAAVKNDPLVKA 318
PBP2_UgpB cd14748
The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; ...
 57-393 3.98e-09

The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold; This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270451 [Multi-domain]  Cd Length: 385  Bit Score: 58.07  E-value: 3.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  57 EALAQAF---QDETGIETQIQLSATDYDQTLRSEMAKDEAPTMFQADG---PSF--------MYSWLDyAADMSDSKIYG 122
Cdd:cd14748    17 EELVDEFnksHPDIKVKAVYQGSYDDTLTKLLAALAAGTAPDVAQVDAswvAQLadsgalepLDDYID-KDGVDDDDFYP 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 123 ELTDSYKDrtlknaDGKPVGIPYAVESYGIIYNKSLLKKYfdaswssvkSIDGLN---NFKALKTVADEIQEHKDDMGVK 199
Cdd:cd14748    96 AALDAGTY------DGKLYGLPFDTSTPVLYYNKDLFEEA---------GLDPEKppkTWDELEEAAKKLKDKGGKTGRY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 200 GaFTSAGMDSSAFRYNFHLPSLPLFYEYRDDGVDMNSvPESVKgtyvdYMQNIYDLYITDATVPasslsGKTMDDATSEF 279
Cdd:cd14748   161 G-FALPPGDGGWTFQALLWQNGGDLLDEDGGKVTFNS-PEGVE-----ALEFLVDLVGKDGVSP-----LNDWGDAQDAF 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 280 ALGEAVFFQDGVWIYSALQDQGfPDEDLGVLPIymgVDGEEKQGLNQVISNYWCVNSKSSqKDQEATQQFLEWLvTSDAA 359
Cdd:cd14748   229 ISGKVAMTINGTWSLAGIRDKG-AGFEYGVAPL---PAGKGKKGATPAGGASLVIPKGSS-KKKEAAWEFIKFL-TSPEN 302

                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 1143275849 360 RESISQDMGLVTPFKTF--DEEAYTVKNPLVEANRE 393
Cdd:cd14748   303 QAKWAKATGYLPVRKSAaeDPEEFLAENPNYKVAVD 338
PBP2_GacH cd14751
The periplasmic-binding component of the putative oligosacchride ABC transporter GacHFG; ...
 50-390 5.37e-09

The periplasmic-binding component of the putative oligosacchride ABC transporter GacHFG; possesses type 2 periplasmic binding fold; This group represents the periplasmic component GacH of an ABC import system. GacH is identified as a maltose/maltodextrin-binding protein with a low affinity for acarbose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270454 [Multi-domain]  Cd Length: 376  Bit Score: 57.77  E-value: 5.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  50 AEEQEKWEALAQAFQDETGietQIQLSAT--DYDQTL---RSEMAKDEAPTMFQAD---GPSFmySWLDYAADMSDSKIY 121
Cdd:cd14751    10 DEEKVLYEKLIPAFEKEYP---KIKVKAVrvPFDGLHnqiKTAAAGGQAPDVMRADiawVPEF--AKLGYLQPLDGTPAF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 122 GELTDsYKDRTLKNA--DGKPVGIPYAVESYGIIYNKSLLKkyfDASWSSVKSIDglnnfkALKTVADEIQEHKddmGVK 199
Cdd:cd14751    85 DDIVD-YLPGPMETNryNGHYYGVPQVTNTLALFYNKRLLE---EAGTEVPKTMD------ELVAAAKAIKKKK---GRY 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 200 GAFTSAgmDSSafrYNFhlpsLPLFYEYRDDGVD-------MNSvPESVKGtyvdyMQNIYDLYITDATVPASSLSGKTM 272
Cdd:cd14751   152 GLYISG--DGP---YWL----LPFLWSFGGDLTDekkatgyLNS-PESVRA-----LETIVDLYDEGAITPCASGGYPNM 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 273 DDAtseFALGEAVFFQDGVWIYSALQ-DQGF-PDEDLGVLPIYMGvdgeeKQGLNQVISNYWCVNSKSSQKDQEATqQFL 350
Cdd:cd14751   217 QDG---FKSGRYAMIVNGPWAYADILgGKEFkDPDNLGIAPVPAG-----PGGSGSPVGGEDLVIFKGSKNKDAAW-KFV 287

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1143275849 351 EWLvTSDAARESISQDMGLVTPFKTFDEEAYTVKNPLVEA 390
Cdd:cd14751   288 KFM-SSAEAQALTAAKLGLLPTRTSAYESPEVANNPMVAA 326
PBP2_Maltodextrin cd13657
The periplasmic binding component of ABC transport system specific for maltodextrin; This ...
 50-360 6.20e-07

The periplasmic binding component of ABC transport system specific for maltodextrin; This group includes the periplasmic maltodextrin-binding protein of a binding protein-dependent ATP-binding cassette transporter. Maltodextrin is a polysaccharide that is used as a food addtive and can be enzymatically produced from any starch . Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270375 [Multi-domain]  Cd Length: 368  Bit Score: 51.22  E-value: 6.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  50 AEEQEKWEALAQAFQDETGIET-QIQLSAT-DYDQTLRSEMAKDEAPTMFqadgpSFMYSWLDYAADMSDSK-IYGELTD 126
Cdd:cd13657    10 GAEEDALQQIIDEFEAKYPVPNvKVPFEKKpDLQNKLLTAIPAGEGPDLF-----IWAHDWIGQFAEAGLLVpISDYLSE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 127 SYKDRTLKNA------DGKPVGIPYAVESYGIIYNKSLLKKyfdaswssvksidglnnfkALKTVADEIQEHKDdmgvkg 200
Cdd:cd13657    85 DDFENYLPTAveavtyKGKVYGLPEAYETVALIYNKALVDQ-------------------PPETTDELLAIMKD------ 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 201 aFTSAGMDSSAFRYNFHLP--SLPLFY----EYRDDGVDMNSV--PESVKGtyVDYMQNIYDLYItdatvpASSLSGKTM 272
Cdd:cd13657   140 -HTDPAAGSYGLAYQVSDAyfVSAWIFgfggYYFDDETDKPGLdtPETIKG--IQFLKDFSWPYM------PSDPSYNTQ 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 273 ddaTSEFALGEAVFFQDGVWIYSALQDQGFpdeDLGVLPI-----------YMGVDGeekqglnqvisnyWCVNSKSSQK 341
Cdd:cd13657   211 ---TSLFNEGKAAMIINGPWFIGGIKAAGI---DLGVAPLptvdgtnpprpYSGVEG-------------IYVTKYAERK 271

                         330
                  ....*....|....*....
gi 1143275849 342 DQEATQQFLEWLVTSDAAR 360
Cdd:cd13657   272 NKEAALDFAKFFTTAEASK 290
malE PRK09474
maltose/maltodextrin ABC transporter substrate-binding protein MalE;
13-398 4.01e-06

maltose/maltodextrin ABC transporter substrate-binding protein MalE;


Pssm-ID: 236533 [Multi-domain]  Cd Length: 396  Bit Score: 48.85  E-value: 4.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  13 AIGLVSVAALSFGALAAC--GNTTA-VDSSKGrvyYlNKKAEEQEKWEAlaqafqdETGIETQIQL--SATD-YDQTlrs 86
Cdd:PRK09474   11 ALSALATLMFSASALAKIeeGKLVIwINGDKG---Y-NGLAEVGKKFEK-------DTGIKVTVEHpdKLEEkFPQV--- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  87 emakdeAPTmfqADGPSFMYSWLDYAADMSDSKIYGELTDS--YKDRTLKNA------DGKPVGIPYAVESYGIIYNKSL 158
Cdd:PRK09474   77 ------AAT---GDGPDIIFWAHDRFGGYAQSGLLAEVTPSkaFKDKLVPFTwdavryNGKLIGYPIAVEALSLIYNKDL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 159 LKKYfDASWSSVKSIDglnnfKALKTvadeiqehkddmgvKGaftsagmdSSAFRYNFHLP--SLPLF-------YEYRD 229
Cdd:PRK09474  148 VPTP-PKTWEEIPALD-----KELKA--------------KG--------KSAIMWNLQEPyfTWPLIaadggyaFKFEN 199

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 230 DGVDMNSVPESVKGTyVDYMQNIYDLyITDATVPAsslsgkTMDDATSE--FALGEAVFFQDGVWIYSALQDQGFpdeDL 307
Cdd:PRK09474  200 GGYDVKDVGVNNAGA-KAGLQFLVDL-VKNKHMNA------DTDYSIAEaaFNKGETAMTINGPWAWSNIDKSGI---NY 268

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 308 GVLPIyMGVDGEEKQGLNQVISNywCVNSKSSQKDqeATQQFLEWLVTSDAARESISQDMGL-VTPFKTFDEEayTVKNP 386
Cdd:PRK09474  269 GVTVL-PTFNGKPSKPFVGVLSA--GINAASPNKE--LAKEFLENYLLTDEGLETVNKDKPLgAVALKSFQEE--LAKDP 341

                         410
                  ....*....|..
gi 1143275849 387 LVEANREYQENG 398
Cdd:PRK09474  342 RIAATMDNAQNG 353
PBP2_TMBP cd14750
The periplasmic-binding component of ABC transport systems specific for trehalose/maltose; ...
 43-404 8.65e-06

The periplasmic-binding component of ABC transport systems specific for trehalose/maltose; possesses type 2 periplasmic binding fold; This group represents the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.


Pssm-ID: 270453 [Multi-domain]  Cd Length: 385  Bit Score: 47.67  E-value: 8.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  43 VYYLNKKAEEQEKWEALAQAFQDETGIET----QIQLSATDYDQTLRSEM-AKDEAPTMFQADGPsfmysWL-DYAADMS 116
Cdd:cd14750     3 TFAAGSDGQEGELLKKAIAAFEKKHPDIKveieELPASSDDQRQQLVTALaAGSSAPDVLGLDVI-----WIpEFAEAGW 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 117 DSKIYGELTDSYKDRTLKNA------DGKPVGIPYAVESYGIIYNKSLLKKYFD---ASWssvksidglnnfKALKTVAD 187
Cdd:cd14750    78 LLPLTEYLKEEEDDDFLPATveantyDGKLYALPWFTDAGLLYYRKDLLEKYGPeppKTW------------DELLEAAK 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 188 EIQEHKDDMgvkGAFTSAGMDSSAFRYNFhlpsLPLFYEYRDDGVD-------MNSvPESVKGtyVDYMQNIYDLYITda 260
Cdd:cd14750   146 KRKAGEPGI---WGYVFQGKQYEGLVCNF----LELLWSNGGDIFDddsgkvtVDS-PEALEA--LQFLRDLIGEGIS-- 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 261 tvPASSLSGKTmDDATSEFALGEAVFFQDGVWIYSALQDQGFPDED-LGVLPIYMGVDGEEKQ---GLNqvisnyWCVNS 336
Cdd:cd14750   214 --PKGVLTYGE-EEARAAFQAGKAAFMRNWPYAYALLQGPESAVAGkVGVAPLPAGPGGGSAStlgGWN------LAISA 284

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1143275849 337 KSsqKDQEATQQFLEWLVTSDAARESISQDMGLVTPFKTFDEEAYTVKNPLVEANREYQENG-------YYDVIS 404
Cdd:cd14750   285 NS--KHKEAAWEFVKFLTSPEVQKRRAINGGLPPTRRALYDDPEVLEAYPFLPALLEALENAvprpvtpKYPEVS 357
PotD COG0687
Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism];
20-168 5.29e-05

Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism];


Pssm-ID: 440451 [Multi-domain]  Cd Length: 348  Bit Score: 45.29  E-value: 5.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  20 AALSFGALAACGNTTAVDSSKGRVYYLNkkaeeqekW-----EALAQAFQDETGIETQIQLSATDydqtlrsemakDEAP 94
Cdd:COG0687     8 GLAAAALAAALAGGAPAAAAEGTLNVYN--------WggyidPDVLEPFEKETGIKVVYDTYDSN-----------EEML 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  95 TMFQADGPSF--MYSWLDYAADMSDSKIYGELTDS----YKD-----RTLKNADGKPVGIPYAVESYGIIYNKSLLKKYF 163
Cdd:COG0687    69 AKLRAGGSGYdvVVPSDYFVARLIKAGLLQPLDKSklpnLANldprfKDPPFDPGNVYGVPYTWGTTGIAYNTDKVKEPP 148


                  ....*
gi 1143275849 164 DaSWS 168
Cdd:COG0687   149 T-SWA 152
PBP2_AlgQ_like_1 cd13580
Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 ...
 61-358 1.75e-03

Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold; This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.


Pssm-ID: 270298 [Multi-domain]  Cd Length: 471  Bit Score: 40.77  E-value: 1.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  61 QAFQDETGIETQIQ-LSATDYDQTLRSEMAKDEAPTMFQADGPSFMYSWLDYAADMSDSKIYGELTDSYK----DRTLKN 135
Cdd:cd13580    26 KYLEEKTNIDVKVKwVPDSSYDEKLNLALASGDLPDIVVVNDPQLSITLVKQGALWDLTDYLDKYYPNLKkiieQEGWDS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 136 A--DGKPVGIPYAVESY---GIIYNKSLLKKYfdaswssvksidGLnnfKALKTVaDEIQE--------------HKDDM 196
Cdd:cd13580   106 AsvDGKIYGIPRKRPLIgrnGLWIRKDWLDKL------------GL---EVPKTL-DELYEvakaftekdpdgngKKDTY 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 197 GVKGAFTSAGMDSSAFRYNFHLPSLPLFYEyrDDGVDmnsVPESVKGTYVDYMQNIYDLY---------ITDATvpassl 267
Cdd:cd13580   170 GLTDTKDLIGSGFTGLFGAFGAPPNNWWKD--EDGKL---VPGSIQPEMKEALKFLKKLYkeglidpefAVNDG------ 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849 268 sgktmDDATSEFALGEAVFFQ----DGVWIYSALQDqGFPDEDLGVLPIYMGVDGEEKQGLNQVISNYWCVNSKSsqKDQ 343
Cdd:cd13580   239 -----TKANEKFISGKAGIFVgnwwDPAWPQASLKK-NDPDAEWVAVPIPSGPDGKYGVWAESGVNGFFVIPKKS--KKP 310

                         330
                  ....*....|....*
gi 1143275849 344 EATQQFLEWLVTSDA 358
Cdd:cd13580   311 EAILKLLDFLSDPEV 325
AfuA COG1840
ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; ...
 59-161 4.18e-03

ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism];


Pssm-ID: 441445 [Multi-domain]  Cd Length: 286  Bit Score: 39.15  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143275849  59 LAQAFQDETGIETQ-IQLSATDYDQTLRSEmAKDEAPTMFQADGPSFMYSW--LDYAADMsDSKIYGELTDSYKDrtlkn 135
Cdd:COG1840     1 LLEAFEKKTGIKVNvVRGGSGELLARLKAE-GGNPPADVVWSGDADALEQLanEGLLQPY-KSPELDAIPAEFRD----- 73

                          90       100
                  ....*....|....*....|....*.
gi 1143275849 136 ADGKPVGIpyAVESYGIIYNKSLLKK 161
Cdd:COG1840    74 PDGYWFGF--SVRARVIVYNTDLLKE 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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