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Conserved domains on  [gi|1024272130|gb|ANB54467|]
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chitobiase [Aeromonas veronii]

Protein Classification

E_set_Cellulase_N domain-containing protein( domain architecture ID 10120361)

E_set_Cellulase_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
E_set_Cellulase_N cd02850
N-terminal Early set domain associated with the catalytic domain of cellulase; E or "early" ...
 3-94 5.71e-20

N-terminal Early set domain associated with the catalytic domain of cellulase; E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.


:

Pssm-ID: 199881  Cd Length: 86  Bit Score: 84.61  E-value: 5.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024272130   3 LLINQVGYECDGHKVALLQTSPVPdlGGYVRLQRLDDGQILFETPLQPAGSVPgWQGRAYWRADFSAFKEPGHYRLEAIT 82
Cdd:cd02850     2 IRVNQVGYLPNAPKVAVVVGDETA--ASTFELVDAATGKVVYTGTLTPAGGDA-ASGETVYIADFSAVTTPGTYYLRVGG 78

                          90
                  ....*....|..
gi 1024272130  83 aqgiARSTLFAI 94
Cdd:cd02850    79 ----VRSYPFEI 86
Glyco_hydro_9 super family cl47592
Glycosyl hydrolase family 9;
104-218 4.45e-05

Glycosyl hydrolase family 9;


The actual alignment was detected with superfamily member pfam00759:

Pssm-ID: 459928 [Multi-domain]  Cd Length: 376  Bit Score: 46.04  E-value: 4.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024272130 104 LSDVIHYFKRQRaSGTFDR------------ADRNARLFGTDQHKDVHGGWFDAsGD-------MSKYLSHLSYANYLNP 164
Cdd:pfam00759   3 LQKSLLFFYAQR-SGKLPDnnrvawrgdshlDDGAAALSGDDGGVDLSGGWYDA-GDyvkfgvpMAFTVTMLLWAYEEFP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1024272130 165 QQtpmvvwallkcrellaprrdIDGVNLCKRLNDEALHGADFLCRMQDESGFFF 218
Cdd:pfam00759  81 DA--------------------YKAAGDLDHILDELKWGLDYLLKMHPSDGVLY 114
Glyco_hydro_9 super family cl47592
Glycosyl hydrolase family 9;
436-501 3.51e-04

Glycosyl hydrolase family 9;


The actual alignment was detected with superfamily member pfam00759:

Pssm-ID: 459928 [Multi-domain]  Cd Length: 376  Bit Score: 42.96  E-value: 3.51e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1024272130 436 NNESGYWWQGENARLASLAAMAFAGARHFPRQSQPLLTYGQRQLDWILGQNPFNACMLAGHGINNP 501
Cdd:pfam00759 249 STGWGFSWDNKVAGYAANAAFLLLVYADLLGDPSKYRDFAKSQIDYLLGDNPLGMSYVVGYGENSP 314
 
Name Accession Description Interval E-value
E_set_Cellulase_N cd02850
N-terminal Early set domain associated with the catalytic domain of cellulase; E or "early" ...
 3-94 5.71e-20

N-terminal Early set domain associated with the catalytic domain of cellulase; E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.


Pssm-ID: 199881  Cd Length: 86  Bit Score: 84.61  E-value: 5.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024272130   3 LLINQVGYECDGHKVALLQTSPVPdlGGYVRLQRLDDGQILFETPLQPAGSVPgWQGRAYWRADFSAFKEPGHYRLEAIT 82
Cdd:cd02850     2 IRVNQVGYLPNAPKVAVVVGDETA--ASTFELVDAATGKVVYTGTLTPAGGDA-ASGETVYIADFSAVTTPGTYYLRVGG 78

                          90
                  ....*....|..
gi 1024272130  83 aqgiARSTLFAI 94
Cdd:cd02850    79 ----VRSYPFEI 86
CelD_N pfam02927
Cellulase N-terminal ig-like domain;
5-80 3.23e-12

Cellulase N-terminal ig-like domain;


Pssm-ID: 427058  Cd Length: 83  Bit Score: 62.25  E-value: 3.23e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1024272130   5 INQVGYECDGHKVALLQTSPVPDLGGYvRLQRLDDGQILFETPLQPAGSVPgWQGRAYWRADFSAFKEPGHYRLEA 80
Cdd:pfam02927   5 VNQVGYLPNGPKVAVVVSTEATTPLSF-QLVDAATGKVVYTGTTTPAGVDA-SSGENVHTIDFSAVTTPGTYYLKV 78
Glyco_hydro_9 pfam00759
Glycosyl hydrolase family 9;
104-218 4.45e-05

Glycosyl hydrolase family 9;


Pssm-ID: 459928 [Multi-domain]  Cd Length: 376  Bit Score: 46.04  E-value: 4.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024272130 104 LSDVIHYFKRQRaSGTFDR------------ADRNARLFGTDQHKDVHGGWFDAsGD-------MSKYLSHLSYANYLNP 164
Cdd:pfam00759   3 LQKSLLFFYAQR-SGKLPDnnrvawrgdshlDDGAAALSGDDGGVDLSGGWYDA-GDyvkfgvpMAFTVTMLLWAYEEFP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1024272130 165 QQtpmvvwallkcrellaprrdIDGVNLCKRLNDEALHGADFLCRMQDESGFFF 218
Cdd:pfam00759  81 DA--------------------YKAAGDLDHILDELKWGLDYLLKMHPSDGVLY 114
Glyco_hydro_9 pfam00759
Glycosyl hydrolase family 9;
436-501 3.51e-04

Glycosyl hydrolase family 9;


Pssm-ID: 459928 [Multi-domain]  Cd Length: 376  Bit Score: 42.96  E-value: 3.51e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1024272130 436 NNESGYWWQGENARLASLAAMAFAGARHFPRQSQPLLTYGQRQLDWILGQNPFNACMLAGHGINNP 501
Cdd:pfam00759 249 STGWGFSWDNKVAGYAANAAFLLLVYADLLGDPSKYRDFAKSQIDYLLGDNPLGMSYVVGYGENSP 314
 
Name Accession Description Interval E-value
E_set_Cellulase_N cd02850
N-terminal Early set domain associated with the catalytic domain of cellulase; E or "early" ...
 3-94 5.71e-20

N-terminal Early set domain associated with the catalytic domain of cellulase; E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.


Pssm-ID: 199881  Cd Length: 86  Bit Score: 84.61  E-value: 5.71e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024272130   3 LLINQVGYECDGHKVALLQTSPVPdlGGYVRLQRLDDGQILFETPLQPAGSVPgWQGRAYWRADFSAFKEPGHYRLEAIT 82
Cdd:cd02850     2 IRVNQVGYLPNAPKVAVVVGDETA--ASTFELVDAATGKVVYTGTLTPAGGDA-ASGETVYIADFSAVTTPGTYYLRVGG 78

                          90
                  ....*....|..
gi 1024272130  83 aqgiARSTLFAI 94
Cdd:cd02850    79 ----VRSYPFEI 86
CelD_N pfam02927
Cellulase N-terminal ig-like domain;
5-80 3.23e-12

Cellulase N-terminal ig-like domain;


Pssm-ID: 427058  Cd Length: 83  Bit Score: 62.25  E-value: 3.23e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1024272130   5 INQVGYECDGHKVALLQTSPVPDLGGYvRLQRLDDGQILFETPLQPAGSVPgWQGRAYWRADFSAFKEPGHYRLEA 80
Cdd:pfam02927   5 VNQVGYLPNGPKVAVVVSTEATTPLSF-QLVDAATGKVVYTGTTTPAGVDA-SSGENVHTIDFSAVTTPGTYYLKV 78
Glyco_hydro_9 pfam00759
Glycosyl hydrolase family 9;
104-218 4.45e-05

Glycosyl hydrolase family 9;


Pssm-ID: 459928 [Multi-domain]  Cd Length: 376  Bit Score: 46.04  E-value: 4.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024272130 104 LSDVIHYFKRQRaSGTFDR------------ADRNARLFGTDQHKDVHGGWFDAsGD-------MSKYLSHLSYANYLNP 164
Cdd:pfam00759   3 LQKSLLFFYAQR-SGKLPDnnrvawrgdshlDDGAAALSGDDGGVDLSGGWYDA-GDyvkfgvpMAFTVTMLLWAYEEFP 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1024272130 165 QQtpmvvwallkcrellaprrdIDGVNLCKRLNDEALHGADFLCRMQDESGFFF 218
Cdd:pfam00759  81 DA--------------------YKAAGDLDHILDELKWGLDYLLKMHPSDGVLY 114
Glyco_hydro_9 pfam00759
Glycosyl hydrolase family 9;
436-501 3.51e-04

Glycosyl hydrolase family 9;


Pssm-ID: 459928 [Multi-domain]  Cd Length: 376  Bit Score: 42.96  E-value: 3.51e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1024272130 436 NNESGYWWQGENARLASLAAMAFAGARHFPRQSQPLLTYGQRQLDWILGQNPFNACMLAGHGINNP 501
Cdd:pfam00759 249 STGWGFSWDNKVAGYAANAAFLLLVYADLLGDPSKYRDFAKSQIDYLLGDNPLGMSYVVGYGENSP 314
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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