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hypothetical protein A4C56_09090 [Elizabethkingia anophelis]
nuclear transport factor 2 family protein( domain architecture ID 233)
nuclear transport factor 2 (NTF2) family protein, similar to Aspergillus flavus scytalone dehydratases, Pseudomonas putida benzene 1,2-dioxygenase subunit beta, and many other members with similar structural details but divergent functions
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
NTF2_like super family | cl09109 | Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 ... |
21-133 | 9.31e-05 | |||
Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of divergent evolution wherein the proteins have many common structural details but diverge greatly in their function. For example, nuclear transport factor 2 (NTF2) mediates the nuclear import of RanGDP and binds to both RanGDP and FxFG repeat-containing nucleoporins while Ketosteroid isomerases catalyze the isomerization of delta-5-3-ketosteroid to delta-4-3-ketosteroid, by intramolecular transfer of the C4-beta proton to the C6-beta position. While the function of the beta sub-unit of the Ring hydroxylating dioxygenases is not known, Scytalone Dehydratases catalyzes two reactions in the biosynthetic pathway that produces fungal melanin. Members of the NTF2-like superfamily are widely distributed among bacteria, archaea and eukaryotes. The actual alignment was detected with superfamily member pfam12893: Pssm-ID: 471850 Cd Length: 116 Bit Score: 39.59 E-value: 9.31e-05
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Name | Accession | Description | Interval | E-value | |||
Lumazine_bd_2 | pfam12893 | Putative lumazine-binding; This is a family of uncharacterized proteins. However, the family ... |
21-133 | 9.31e-05 | |||
Putative lumazine-binding; This is a family of uncharacterized proteins. However, the family belongs to the NTF2-like superfamily of various enzymes, and some of the members of the family are putative dehydrogenases. Pssm-ID: 432859 Cd Length: 116 Bit Score: 39.59 E-value: 9.31e-05
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Name | Accession | Description | Interval | E-value | |||
Lumazine_bd_2 | pfam12893 | Putative lumazine-binding; This is a family of uncharacterized proteins. However, the family ... |
21-133 | 9.31e-05 | |||
Putative lumazine-binding; This is a family of uncharacterized proteins. However, the family belongs to the NTF2-like superfamily of various enzymes, and some of the members of the family are putative dehydrogenases. Pssm-ID: 432859 Cd Length: 116 Bit Score: 39.59 E-value: 9.31e-05
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DUF4440 | pfam14534 | Domain of unknown function (DUF4440); |
30-133 | 3.32e-03 | |||
Domain of unknown function (DUF4440); Pssm-ID: 434023 [Multi-domain] Cd Length: 107 Bit Score: 35.45 E-value: 3.32e-03
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Blast search parameters | ||||
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