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Conserved domains on  [gi|973199831|gb|ALX09048|]
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response regulator receiver and ANTAR domain protein [Acetivibrio thermocellus AD2]

Protein Classification

ANTAR domain-containing response regulator( domain architecture ID 11467116)

response regulator with a signal receiver (REC) domain and RNA binding antiterminator (ANTAR) domain involved in transcriptional antitermination, similar to Mycobacterium tuberculosis transcriptional regulatory protein pdtaR that is a member of the two-component regulatory system pdtaR/pdtaS

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 3-189 2.55e-36

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


:

Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 125.07  E-value: 2.55e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831   3 SILIVSSSLKVSSTLEELLKfNSSYNEIVMARNAGEAKRILLDRDFDLCIINTPLTDEFGTNLAINIANRETSQVMLIVK 82
Cdd:COG3707    5 RVLVVDDEPLRRADLREGLR-EAGYEVVAEAADGEDAVELVRELKPDLVIVDIDMPDRDGLEAARQISEERPAPVILLTA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831  83 SELEDEISDKVEDYGIFVVAKPVNRQLFWSALKLISASHNRMKGLKKQNEQLQKKIEDIKFVDRAKCVLIEYLKMSEAEA 162
Cdd:COG3707   84 YSDPELIERALEAGVSAYLVKPLDPEDLLPALELALARFRELRALRRELAKLREALEERKLIERAKGILMERRGLSEDEA 163

                        170       180
                 ....*....|....*....|....*..
gi 973199831 163 HRFIEKQAMDLRVTKREIASRILKTYE 189
Cdd:COG3707  164 YRLLRKQAMDRRVKLAEVAEAILAAAE 190
 
Name Accession Description Interval E-value
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 3-189 2.55e-36

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 125.07  E-value: 2.55e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831   3 SILIVSSSLKVSSTLEELLKfNSSYNEIVMARNAGEAKRILLDRDFDLCIINTPLTDEFGTNLAINIANRETSQVMLIVK 82
Cdd:COG3707    5 RVLVVDDEPLRRADLREGLR-EAGYEVVAEAADGEDAVELVRELKPDLVIVDIDMPDRDGLEAARQISEERPAPVILLTA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831  83 SELEDEISDKVEDYGIFVVAKPVNRQLFWSALKLISASHNRMKGLKKQNEQLQKKIEDIKFVDRAKCVLIEYLKMSEAEA 162
Cdd:COG3707   84 YSDPELIERALEAGVSAYLVKPLDPEDLLPALELALARFRELRALRRELAKLREALEERKLIERAKGILMERRGLSEDEA 163

                        170       180
                 ....*....|....*....|....*..
gi 973199831 163 HRFIEKQAMDLRVTKREIASRILKTYE 189
Cdd:COG3707  164 YRLLRKQAMDRRVKLAEVAEAILAAAE 190
ANTAR pfam03861
ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding ...
 137-181 1.94e-12

ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.


Pssm-ID: 427550 [Multi-domain]  Cd Length: 46  Bit Score: 58.88  E-value: 1.94e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 973199831  137 KIEDIKFVDRAKCVLIEYLKMSEAEAHRFIEKQAMDLRVTKREIA 181
Cdd:pfam03861   1 ALESRKVIEQAKGILMERLGLSEDEAFRLLRKLSMDRNVKLREVA 45
ANTAR smart01012
ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found ...
 131-185 1.81e-11

ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins; The majority of the domain consists of a coiled-coil.


Pssm-ID: 198080 [Multi-domain]  Cd Length: 55  Bit Score: 56.72  E-value: 1.81e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 973199831   131 NEQLQKKIEDIKFVDRAKCVLIEYLKMSEAEAHRFIEKQAMDLRVTKREIASRIL 185
Cdd:smart01012   1 LEQLREALESRKVIEQAKGILMERRGLSEEEAFELLRKLAMDRNVKLRDVAEAIV 55
 
Name Accession Description Interval E-value
AmiR COG3707
Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding ...
 3-189 2.55e-36

Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains [Signal transduction mechanisms, Transcription];


Pssm-ID: 442921 [Multi-domain]  Cd Length: 194  Bit Score: 125.07  E-value: 2.55e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831   3 SILIVSSSLKVSSTLEELLKfNSSYNEIVMARNAGEAKRILLDRDFDLCIINTPLTDEFGTNLAINIANRETSQVMLIVK 82
Cdd:COG3707    5 RVLVVDDEPLRRADLREGLR-EAGYEVVAEAADGEDAVELVRELKPDLVIVDIDMPDRDGLEAARQISEERPAPVILLTA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831  83 SELEDEISDKVEDYGIFVVAKPVNRQLFWSALKLISASHNRMKGLKKQNEQLQKKIEDIKFVDRAKCVLIEYLKMSEAEA 162
Cdd:COG3707   84 YSDPELIERALEAGVSAYLVKPLDPEDLLPALELALARFRELRALRRELAKLREALEERKLIERAKGILMERRGLSEDEA 163

                        170       180
                 ....*....|....*....|....*..
gi 973199831 163 HRFIEKQAMDLRVTKREIASRILKTYE 189
Cdd:COG3707  164 YRLLRKQAMDRRVKLAEVAEAILAAAE 190
ANTAR pfam03861
ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding ...
 137-181 1.94e-12

ANTAR domain; ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.


Pssm-ID: 427550 [Multi-domain]  Cd Length: 46  Bit Score: 58.88  E-value: 1.94e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 973199831  137 KIEDIKFVDRAKCVLIEYLKMSEAEAHRFIEKQAMDLRVTKREIA 181
Cdd:pfam03861   1 ALESRKVIEQAKGILMERLGLSEDEAFRLLRKLSMDRNVKLREVA 45
ANTAR smart01012
ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found ...
 131-185 1.81e-11

ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins; The majority of the domain consists of a coiled-coil.


Pssm-ID: 198080 [Multi-domain]  Cd Length: 55  Bit Score: 56.72  E-value: 1.81e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 973199831   131 NEQLQKKIEDIKFVDRAKCVLIEYLKMSEAEAHRFIEKQAMDLRVTKREIASRIL 185
Cdd:smart01012   1 LEQLREALESRKVIEQAKGILMERRGLSEEEAFELLRKLAMDRNVKLRDVAEAIV 55
CitB COG4565
DNA-binding response regulator DpiB of citrate/malate metabolism [Transcription, Signal ...
 1-134 1.39e-03

DNA-binding response regulator DpiB of citrate/malate metabolism [Transcription, Signal transduction mechanisms];


Pssm-ID: 443622 [Multi-domain]  Cd Length: 138  Bit Score: 37.26  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973199831   1 MDSILIVSSSLKVSSTLEELLKFNSSYNEIVMARNAGEAKRILLDRDFDLCI--INTPltDEFGTNLAINIANRETSQVM 78
Cdd:COG4565    3 MIRVLIVEDDPMVAELLRRYLERLPGFEVVGVASSGEEALALLAEHRPDLILldIYLP--DGDGLELLRELRARGPDVDV 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 973199831  79 LIVKSELEDEISDKVEDYGIF-VVAKPVNRQLFWSALKLISASHNRMKGLkkQNEQL 134
Cdd:COG4565   81 IVITAARDPETVREALRAGVVdYLIKPFTFERLREALERYLEYRRLLRED--QEEDL 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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